Kuge Yuji 久下裕司

… Alternative Names

KUGE Yuji 久下裕司

KUGA Yuji 久下祐司

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Researcher Number	70321958
Other IDs
Affiliation (Current)	2025: 北海道大学, アイソトープ総合センター, 教授
Affiliation (based on the past Project Information) *help	2008 – 2025: 北海道大学, アイソトープ総合センター, 教授 2012: 北海道大学, 大学院・医学研究科, 教授 2007 – 2010: 北海道大学, 医学研究科, 教授 2009: アイソトープ総合センター, 教授 2009: 北海道大学, 学内共同利用施設, 教授 … More 2008: 北海道大学, アイソトープ総合研究センター, 教授 2007 – 2008: Hokkaido University, Graduate school of Medicine, Professor 2007: 北海道大学, 大学院・医学研究科・先端医学講座・トレーサ情報分析学分野, 教授 2005 – 2006: Kyoto University Graduate School of Pharmaceutical Science, Department of Patho-Functional Bioanalysis, Associate Professor, 大学院・薬学研究科病態機能分析学, 助教授 2002 – 2006: 京都大学, 薬学研究科, 助教授 2003 – 2004: 京都大学, 大学院・薬学研究科, 助教授 2000 – 2003: 北海道大学, 大学院・医学研究科, 寄附講座教員 2002: 北海道大学, 大学院・医学研究科, 助教授 Less
Review Section/Research Field	Principal Investigator Radiation science / Radiation science / Basic Section 52040:Radiological sciences-related / Medium-sized Section 52:General internal medicine and related fields / General internal medicine and related fields Except Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related / Basic Section 63020:Radiation influence-related / Medium-sized Section 52:General internal medicine and related fields / Plastic surgery … More / Cerebral neurosurgery / Radiation science / Basic Section 56010:Neurosurgery-related / Basic Section 52010:General internal medicine-related / Basic Section 90130:Medical systems-related / Surgical dentistry / Physical pharmacy / Respiratory organ internal medicine Less
Keywords	Principal Investigator 放射線 / 核医学診断 / PET / 組織因子 / 分子イメージング / 動脈硬化 / フェロトーシス / 不安定プラーク / 癌 / プロスタグランジン … More / がん治療 / 核医学 / 治療 / ポジトロンCT(PET) / シングルフォトンCT(SPECT) / シクロオキシゲナーゼ(COX-2) / イメージンング / 不安定性評価 / イメージング / ディスポ・チップ型 / PET薬剤合成装置 / ディスポチップ / 自己遮蔽型 / オン・デマンド / 薬剤合成装置 / RI内用療法 / Therapy / Molecular imaging / Cancer / Radioisotope / single photon CT (SPECT) / positron CT (PET) / cyclooxygenase-2(COX-2) / prostaglandins / molecular imaging / pathophysiology of cerebral ischemia / シクロオキシナーゼ(COX-2) / 脳虚血病態 / インテグリンαvβ3 / インテグリンαvβ３ / マクロファージ / 低酸素イメージング / 人工抗体 / 臨床 / 生体分子 / 移植・再生医療 / マイクロアレイ / リハビリテーション / 脳神経疾患 / 有機化学 / 薬学 / 医療・福祉 / マイクロ・ナノデバイス / シンロオキシゲナーゼ(COX-2) / シクロオキシゲナーゼ / チミジン / 核酸合成 / 鑑別診断 / 炎症 / 腫瘍 / インビボイメージング / positron emission tomography / fluorodeoxyglucose / insulin / glucose / inflammation / tumor … More Except Principal Investigator 放射線 / PET / イメージング / 腫瘍 / 分子イメージング / チミジンホスホリラーゼ / 癌 / 核医学 / 動脈硬化 / 核医学診断 / アポトーシス / tumor / レドックス / 治療戦略 / 5-フルオロウラシル / がん治療 / がん / 血管新生 / 不安定プラーク / 画像診断 / 放射線治療 / glucose metabolism / deoxyglucose / 生体金属 / 治療用放射性薬剤 / 核医学治療 / 光治療 / 化学療法 / 低酸素 / Prostaglandin / JTE-522 / S100A9 / Rat / Spreading depression / Cyclooxygenase-2 / FDG / inflammation / positron emission tomography / 核医学診断薬 / 治療効果予測 / 治療効果 / 低酸素細胞 / 悪性黒色腫 / デオキシグルコース / エミッショントモグラフィ / rat / 非線形最適化 / 体幹部定位放射線照射 / プラスチック検出器 / モンテカルロ法 / 電子線トラック解析 / 量子線シミュレーション / 放射性医薬品 / emission tomography / がん特異的代謝 / ラジオミクス / セノリティクス / 幹細胞シート / 間葉系幹細胞 / 脳虚血 / シート / 幹細胞 / もやもや病 / がん微小環境 / 乳酸 / エネルギー代謝 / 微小環境 / がん免疫 / 酸化ストレス / EPRイメージング / O-15水 / 定量 / ポジトロン断層法 / deep neural network / 血流 / 糖代謝 / FDG-PET/CT / deep learning / 人工知能 / ESR / 核医学プローブ / 移植腫瘍 / フェロトーシス / 光音響 / 光音響イメージング / プロテオーム / 質量分析イメージング / Id-1 / 細胞老化 / アスタチン / トランスポーター / 個別化医療 / 有機カチオントランスポーター / イメージング剤 / がん治療効果予測 / α線医薬品 / サイクロトロン / ラジオアイソトープ / α線内用療法 / 自動化 / アルファ線放出核種 / 自動化装置 / 加速器 / 短寿命α線放出核種 / 包括的映像法 / PET-MRI / MRI / PET-CT / 活動性病変 / 低酸素イメージング / 治療開発 / 再酸素化 / 抗腫瘍効果 / エリブリン / 低酸素改善 / 薬学 / がんのイメージング / がんイメージング / 細胞周期制御因子 / サイクリン依存性キナーゼ / CDK2 / がんのイメジング / 治療 / 核医学イメージング / Theranostics / 自動合成 / 放射性診断薬剤 / 放射性薬剤 / ＰＥＴ／ＳＰＥＣＴ / IIMU / がんの核医学的分子イメージング / ５－FUプロドラッグ / 5-フルオロウラシル（5-FU） / 担癌モデル動物 / 抗がん剤Paclitaxel / プロドラッグ / 5－フルオロウラシル（5-FU) / SPECTイメージング / ヨウ素標識IIMU / チミジンホスホリラーゼ（TP） / 核医学（PET) / 核医学（PET） / FIMISO / 核医学 (PET) / 核医学(PET) / 動物モデル / 臨床研究 / 口腔がん / FMISO / 頭頸部癌 / 治療抵抗性 / 遺伝子応答 / 遺伝子イメージング / チミジンホスホリラーゼ阻害薬 / がんの悪性度評価 / F-18標識プローブ / 心血管疾患 / 循環器 / radiolabeled molecular probe / macrophage / lectine-like oxidized LDL receptor / glucose derivative / radiation detector / molecular imaging / vulnerable plaque / thrombosis / F-18 / LOX-1 / 超小型放射線検出器 / 放射性プローブ / マクロファージ / スカベンジャー受容体 / グルコース誘導体 / 放射線検出器 / 血栓 / benzodiazepine receptor / neuronal viability / iomazenil / cerebral blood flow / focal ischemia / cyclooxygenase-2 / MAPK phosphatase / Neurogenesis / Environmental enrichment / Focal ischemia / RAT / stereoselective synthesis / imaging / single photon computed tomography / nucleoside / nitroimidazole / hypoxia / 低酸素細胞親和性 / 生体内分布 / 立体選択的合成 / X線結晶構造解析 / ヌクレオシド / シングルフォトンCT / 腫瘍診断薬剤 / ニトロイミダゾール / glucose transporter / ARG / ヘキソキナーゼ / グルコーストランスポータ / ステロイド / 非感染症炎症 / 感染症炎症 / glucose transortor / glucose transportor / radiopharmaceutical / Radioiodine / Rhodacyanine derivative / lipophilic cation / membrane potentia / mitochondria / 脂溶性カオチン / ログシアニン誘導体 / 放射性ヨウ素 / ロダシアニン誘導体 / 脂溶性カチオン / 膜電位 / ミトコンドリア / SPECT / ドキシフルリジン / カペシタビン / 抗がん剤 / 神経化学的評価 / 放射性診断薬 / 分子標的 / 治療効果判定 / 個体差 / 放射性画像診断薬 / 個別化薬物療法 / 薬物代謝酵素活性 / 個体差要因 / 遺伝子発現解析 / 精神神経疾患 / 内用放射線治療 / ＳＰＥＣＴ / ＰＥＴ / SPECT/CT / PET/CT / 細胞増殖 / がんの分子標的療法 / がん分子イメージング / 癌転移 / リンパ節 / 転移 / in-transit転移 / マウス / in-transit 転移 / リンパ浮腫 / 半導体PET / FDG(フルオロデオキシグルコース) / 予後 / FMISO(フルオロミソニダゾール) / PET・PET-CT / 腫瘍内低酸素 / プラスチック檢出器 / 胃癌 / 細胞遊走 / 生体の動き / 医学研究 / 動体追跡 / ポジトロンCT / 代謝 / 頭部外傷 / 核医学(PETを含む) / 循環器・高血圧 / 悪性黒色種 / ヒアルロン酸 / リンパ行性転移 / 皮膚癌 / ドラッグデリバリーシステム / 再生医学 / 痴呆 / トランスレーショナルリサーチ / 放射線画像診断 / アルツハイマー病 / brain derived neurotrophic factor / focal brain ischemia / enrich environment / Enrich environment / Brain derived neurotrophic factor / Enrich environme / Enriched environment Brain derived neurotrophic factor / 局所脳虚血 / リハビリテーション / 量子線シュミレーション / ヘリコバクター・ピロリ / 炎症性発癌 / 分子標的療法 / 放射線医薬品 / 放射線照射 / 癌免疫賦活 / 放射線ホルメシス / CGP-12177 / トレーサー実験 / 卵白アルブミン / 喘息 / 気道過敏性 / 気管支喘息 / β受容体 Less

The dynamic analysis and control of radiation-induced cell death through the intervention of biomolecular metal redox and cancer-specific metabolism.
- Principal Investigator
  
  安井博宣
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Hokkaido University
Prediction and assessment of ferroptosis-inducing cancer therapy using a novel PET probe targeting Tf-receptorPrincipal Investigator
- Principal Investigator
  
  久下裕司
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hokkaido University
Development of PET/EPR functional imaging method for early diagnosis of cancer
- Principal Investigator
  
  藤井博匡
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Health Sciences University of Hokkaido
間葉系幹細胞シートを用いたもやもや病の間接血行再建術における包括的研究
- Principal Investigator
  
  藤村幹
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
Research for local control and high accuracy of cancer senolytic therapy by non-invasive imaging
- Principal Investigator
  
  安井博宣
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Hokkaido University
血管新生因子PD-ECGFを標的としたAt-211標識治療用放射性薬剤の基礎検討
- Principal Investigator
  
  西嶋剣一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Fukushima Medical University
エネルギー代謝に着目した核医学イメージングによるがん微小環境評価
- Principal Investigator
  
  小川美香子
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hokkaido University
Spatio-temporal dynamics analysis of cell death induction due to disruption of biometal homeostasis and its application to radiotherapy
- Principal Investigator
  
  安井博宣
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Hokkaido University
Ferroptosis imaging with PET: Challenge to assess vulnerability of atherosclerotic plaquesPrincipal Investigator
- Principal Investigator
  
  KUGE YUJI
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Hokkaido University
PET imaging for cancer treatment inducing ferrotosisPrincipal Investigator
- Principal Investigator
  
  久下裕司
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hokkaido University
Use of digital PET and deep learning for simultaneous quantification of tumor blood flow and metabolism from FDG PET
- Principal Investigator
  
  Hirata Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hokkaido University
Development of thymidine phosphorylase imaging techniques precisely targeted to the tumor for personalized medicine
- Principal Investigator
  
  Akizawa Hiromichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Showa Pharmaceutical University
PD-ECGF targeted tumor treatment with new At-211 radiolabeled uracil derivatives
- Principal Investigator
  
  NISHIJIMA Ken-ichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Fukushima Medical University
Development of a MS imaging-based diagnosis for novel cancer senotherapy
- Principal Investigator
  
  Yasui Hironobu
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Hokkaido University
Elucidation of the Mechanism of Photoimmunotherapy Using Molecular Imaging and Development of New Drugs
- Principal Investigator
  
  Ogawa Mikako
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hokkaido University
Development of a novel radiotherapy targeting iron-dependent cell death ferroptosis
- Principal Investigator
  
  YASUI HIRONOBU
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Hokkaido University
Development of new therapeutic strategies for hypoxic tumors
- Principal Investigator
  
  Shiga Tohru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Fukushima Medical University
  Hokkaido University
Assessment of unstable plaque by PET, CT, and MRI combination
- Principal Investigator
  
  Tamaki Nagara
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto Prefectural University of Medicine
Development of Robotic Purification and Labeling Technology to Reduce Radiation Exposure in Short-lived Alpha-ray Drug Manufacturing Process
- Principal Investigator
  
  wada youichiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  The University of Tokyo
Development of a radioactive probe targeting the cell cycle regulatory factor CDK2
- Principal Investigator
  
  Kitaura Hirotake
- Project Period (FY)
  2017 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Health Sciences University of Hokkaido
A new disposable chip type PET drug synthesizer for on-demand PET examinationPrincipal Investigator
- Principal Investigator
  
  KUGE YUJI
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  General internal medicine and related fields
- Research Institution
  Hokkaido University
New strategy for oral cancer based on molecular imaging reflecting therapeutic resistance
- Principal Investigator
  
  KITAGAWA Yoshimasa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hokkaido University
Prediction of response to anticancer therapy by thymidine phosphorylase imaging: pre-clinical proof of concept
- Principal Investigator
  
  Zhao Songji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Fukushima Medical University
Theranostics by combination with nuclear and optical methods
- Principal Investigator
  
  Ogawa Mikako
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
A Challenge of radio-isotope therapy for atherosclerosis: Development of a radiopharmaceutical to suppress macrophage infiltrationPrincipal Investigator
- Principal Investigator
  
  KUGE YUJI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Vulnerability Assessment of Atherosclerosis by PET
- Principal Investigator
  
  Tamaki Nagara
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto Prefectural University of Medicine
  Hokkaido University
がん悪性度診断ための新規PET用チミジンホスホリラーゼＦ18イメージング剤の開発
- Principal Investigator
  
  馮飛
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Nuclear medicine imaging toward therapeutic strategy of atherosclerosis: Experimental research to establish EBMPrincipal Investigator
- Principal Investigator
  
  KUGE Yuji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Usefulness of imaging tumor-specific enzyme expression by radiopharmaceuticals with thymidine phosphorylase inhibitory potency
- Principal Investigator
  
  Ohkua Kazue
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Health Sciences University of Hokkaido
PD-ECDF-targeted tumor imaging: Development of production system for I-123 labeled compound
- Principal Investigator
  
  Nishijima Ken-ichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Development of a molecular targeted radiolabeled diagnostic agent useful for personalized drug therapy of psychoneurotic diseases
- Principal Investigator
  
  KAWAI Keiichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Prediction of efficacy of anticancer agents by in vivo imaging of thymidine phosphorylase
- Principal Investigator
  
  AKIZAWA Hiromichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Showa Pharmaceutical University
Specific imaging of vulnerable atherosclerotic plaque: development of a novel SPECT probe using low molecular artificial antibodyPrincipal Investigator
- Principal Investigator
  
  KUGE YUJI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Molecular imaging in tumor proliferation and angiogenesis: Development of a early assessment tool for measuring the tumor response to treatment with molecular targeted drugs
- Principal Investigator
  
  ZHAO SONGJI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Development of radioiolabeled uracil derivatives as radionuclide therapeutic agents for thymidine phosphorylase expressing tumors
- Principal Investigator
  
  OHKURA Kazue
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Health Sciences University of Hokkaido
Early andspecific detection of unstable atherosclerotic pl:aqTuiesssue factor imaging using pre-targeting systemsPrincipal Investigator
- Principal Investigator
  
  KUGE Yuji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Clarifying the metastatic mechanisms of melanoma by imaging techniques
- Principal Investigator
  
  FURUKAWA Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Plastic surgery
- Research Institution
  Hokkaido University
Research for Real-time Tracking Medical Science
- Principal Investigator
  
  SHIRATO Hiroki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
腫瘍内低酸素イメージングによる「がん」のプロファイリング
- Principal Investigator
  
  TAKEI Toshiki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
低酸素領域と血管新生因子のダブルターゲティング標識薬剤によるRI治療への挑戦Principal Investigator
- Principal Investigator
  
  久下裕司
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Molecular imaging for dynamic analysis of cancer pathological states : Toward clinical molecular imagingPrincipal Investigator
- Principal Investigator
  
  KUGE Yuji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Radionuclide imaging for tissue characterization and treatment effect of experimental atherosclerosis
- Principal Investigator
  
  TAMAKI Nagara
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
The relationship between the effect of rehabilitation and loss of neuronal integrity in patients with brain injury.
- Principal Investigator
  
  SHIGA Tohru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Development of a radiolabeled uracil derivative as a potential PET tracer for angiogenesis imaging.
- Principal Investigator
  
  OHKURA Kazue
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Health Sciences University of Hokkaido
Development of probes for the systematic analysis of Alzheimer's disease : establishment of a new diagnostic imaging.
- Principal Investigator
  
  SAJI Hideo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
New lymphatic imaging with indocyanine green (ICG) dye labeled hyaluronic acid derivative
- Principal Investigator
  
  FURUKAWA Hiroshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Plastic surgery
- Research Institution
  Hokkaido University
脳機能再生機構の解析と分子イメージング~臨床画像診断の実現を目指して~Principal Investigator
- Principal Investigator
  
  久下裕司
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
不安定動脈硬化プラークの描出を目的とするSPECT分子イメージングプローブの開発
- Principal Investigator
  
  佐治英郎
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Interactive Radiotherapy
- Principal Investigator
  
  SHIRATO Hiroki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Gene expression and protein synthesis after transient focal ischemia under an enriched environment in rats
- Principal Investigator
  
  YOKOTA Chiaki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  National Cardiovascular Center Research Institute
核医学的手法を用いたプラーク性状評価に関する研究
- Principal Investigator
  
  玉木長良
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
マイクロリアクタによるポジトロンプローブの合成:チップ型自動合成装置の開発へPrincipal Investigator
- Principal Investigator
  
  久下裕司
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
核医学的手法を用いた放射線ホルメシスによる癌免疫賦活(アポトーシス)の検討
- Principal Investigator
  
  MORITA Koichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
癌の分子標的療法:分子イメージングによる早期治療効果の評価
- Principal Investigator
  
  NAKADA Kunihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Molecular imaging and strategies for cancer treatment: A Study to achieve noninvasive in vivo pathological evaluation by molecular imagingPrincipal Investigator
- Principal Investigator
  
  KUGE Yuji
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
  Kyoto University
動脈硬化病態の解析と分子イメージング:プロスタグランジン合成酵素を標的としてPrincipal Investigator
- Principal Investigator
  
  久下裕司
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Molecular imaging for noninvasive evaluation of atherosclerotic plaque vulnerability
- Principal Investigator
  
  SAJI Hideo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Development of novel labeled nucleosides for spect imaging of tumor tissue.
- Principal Investigator
  
  OHKURA Kazue
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Health Sciences University of Hokkaido
Prostaglandin synthesis in response to spreading depression and focal brain ischemia
- Principal Investigator
  
  YOKOTA Chiaki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  National Cardiovascular Center Research Institute
喘息肺β受容体の発現に関する核医学的研究
- Principal Investigator
  
  山口悦郎
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Aichi Medical University
  Hokkaido University
核酸合成・PG合成酵素のインビボイメージング:腫瘍・炎症の鑑別診断への挑戦Principal Investigator
- Principal Investigator
  
  久下裕司
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
FDG-PET検査の改良による腫瘍の鑑別診断法の開発:膜輸送遺伝子・酵素学的検討
- Principal Investigator
  
  玉木長良
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Basic study and application of differentiating malignant tumors from inflammation using PET drugs
- Principal Investigator
  
  NAKADA Kunihiro, 塚本江利子
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Molecular imaging and patho-functional analysis of cerebral ischemia : focused on prostaglandin synthasesPrincipal Investigator
- Principal Investigator
  
  KUGE Yuji
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
Development of a radioiodinated lipophilic cation as a new SPECT radiopharmaceutical for cancer diagnosis.
- Principal Investigator
  
  SAJI Hideo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
腫瘍/炎症内ブドウ糖代謝・膜輸送遺伝子と背景因子:腫瘍鑑別診断のための基礎的研究Principal Investigator
- Principal Investigator
  
  久下裕司
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University

[Book] Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy2016
- Author(s)
  Shimizu Y, Hanzawa H, Zhao Y, Nishijima K, Fukura S, Sakamoto T, Zhao S, Tamaki N, Kuge Y. (Kuge Y, Shiga T, Tamaki, eds)
- Total Pages
  326
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15H04898
[Book] Perspectives on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy2016
- Author(s)
  Shimizu Y, Hanzawa H, Zhao Y, Nishijima K, Fukura S, Sakamoto T, Zhao S, Tamaki N, Kuge Y
- Total Pages
  326
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-26293268
[Book] Molecular Imaging for the Assessment of Tumor Malignancy and Response to Therapy2010
- Author(s)
  Kuge Y et al.
- Publisher
  Tamaki N, Kuge Y eds. Springer (Springer Science+Business Media), Heidelberger
- Data Source
  KAKENHI-PROJECT-21249065
[Book] In Molecular Imaging for Integrated Medical Therapy and Drug Development.-Molecular imaging for the assessment of tumor malignancy and response to therapy.(分担執筆)2010
- Author(s)
  Kuge Y, Zhao S, Takei T
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-21591539
[Book] Molecular Imaging for Integrated Medical Therapy and Drug Development(Tamaki N, Kuge Y eds.)(Molecular Imaging for the Assessment of Tumor Malignancy and Response to Therapy.)2010
- Author(s)
  Kuge Y, Zhao S, Takei T, Tamaki N
- Publisher
  Springer (Springer Science+Business Media), Heidelberger
- Data Source
  KAKENHI-PROJECT-20390320
[Book] Molecular Imaging for Integrated Medical Therapy and Drug Development. State of the art and future perspectives.2010
- Author(s)
  Tamaki N, Kuge Y (eds.)
- Total Pages
  303
- Publisher
  Springer, Tokyo
- Data Source
  KAKENHI-PROJECT-20390321
[Book] Molecular Imaging for Integrated Medical Therapy and Drug Development.State of the art and future perspectives.2010
- Author(s)
  Talnaki N, Kuge Y編集
- Total Pages
  303
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20390321
[Book] PET and Molecular Imaging -State of the art and future perspectives-2004
- Author(s)
  Kuge Y et al.
- Total Pages
  285
- Publisher
  Elsevier Science B.V.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370266
[Book] PET and Molecular Imaging -State of the art and future perspectives-2004
- Author(s)
  Kuge Y 他
- Total Pages
  285
- Publisher
  Elsevier Science B.V
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370266
[Book] PET and Molecular Imaging : State of the art and future perspectives.2004
- Author(s)
  Kuge Y, Kaji T, Hikosaka K, Yokota C, et al.
- Publisher
  Elsevier Science
- Data Source
  KAKENHI-PROJECT-15591559
[Journal Article] Application of copper (I) selective ligands for PET imaging of reactive oxygen species through metabolic trapping2024
- Author(s)
  Tada Tetsuro、Mizuno Yuki、Shibata Yuki、Yasui Hironobu、Kuge Yuji
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 134-135 Pages: 108914-108914
- DOI
  10.1016/j.nucmedbio.2024.108914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19433
[Journal Article] In vivo imaging of acute physiological responses after treatment of cancer with near-infrared photoimmunotherapy2023
- Author(s)
  Nakajima Kohei、Sugikawa Akiyo、Yasui Hironobu、Higashikawa Kei、Suzuki Chie、Natsume Takahiro、Suzuki Motofumi、Takakura Hideo、Tomita Mayu、Takahashi Sachi、Hirata Kenji、Magata Yasuhiro、Kuge Yuji、Ogawa Mikako
- Journal Title
  
  Molecular Imaging and Biology
  
  Volume: 25 Issue: 4 Pages: 648-658
- DOI
  10.1007/s11307-023-01822-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18259, KAKENHI-PROJECT-23K14332, KAKENHI-PROJECT-23K24270, KAKENHI-PROJECT-23K24994
[Journal Article] Eribulin improves tumor oxygenation demonstrated by 18F-DiFA hypoxia imaging, leading to radio-sensitization in human cancer xenograft models2021
- Author(s)
  Bo Tomoki、Yasui Hironobu、Shiga Tohru、Shibata Yuki、Fujimoto Masaki、Suzuki Motofumi、Higashikawa Kei、Miyamoto Naoki、Inanami Osamu、Kuge Yuji
- Journal Title
  
  European Journal of Nuclear Medicine and Molecular Imaging
  
  Volume: 49 Issue: 3 Pages: 821-833
- DOI
  10.1007/s00259-021-05544-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00443, KAKENHI-PROJECT-19H04264, KAKENHI-PROJECT-20KK0250
[Journal Article] Transferrin-based radiolabeled probe predicts the sensitivity of human renal cancer cell lines to ferroptosis inducer erastin2021
- Author(s)
  Shibata Yuki、Yasui Hironobu、Higashikawa Kei、Kuge Yuji
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 26 Pages: 100957-100957
- DOI
  10.1016/j.bbrep.2021.100957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19254, KAKENHI-PROJECT-20H00443, KAKENHI-PROJECT-19H04264, KAKENHI-PROJECT-20KK0250
[Journal Article] Biodistribution and internal radiation dosimetry of a novel probe for thymidine phosphorylase imaging, [123I]IIMU, in healthy volunteers2020
- Author(s)
  Watanabe Shiro、Nishijima Ken-ichi、Okamoto Shozo、Magota Keiichi、Hirata Kenji、Toyonaga Takuya、Shiga Tohru、Kuge Yuji、Tamaki Nagara
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 34 Issue: 8 Pages: 595-599
- DOI
  10.1007/s12149-020-01469-4
- Data Source
  KAKENHI-PROJECT-19K08180
[Journal Article] Preclinical investigation of potential use of thymidine phosphorylase-targeting tracer for diagnosis of nonalcoholic steatohepatitis2020
- Author(s)
  Higashikawa Kei、Horiguchi Sawako、Tarisawa Makoto、Shibata Yuki、Ohkura Kazue、Yasui Hironobu、Takeda Hiroshi、Kuge Yuji
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 82-83 Pages: 25-32
- DOI
  10.1016/j.nucmedbio.2019.12.006
- NAID
  120006980029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17255, KAKENHI-PROJECT-20H00443, KAKENHI-PROJECT-18H03548, KAKENHI-PROJECT-18K19254
[Journal Article] Voxel based comparison and texture analysis of 18F-FDG and 18F-FMISO PET of patients with head-and-neck cancer2019
- Author(s)
  Kroenke Markus、Hirata Kenji、Gafita Andrei、Watanabe Shiro、Okamoto Shozo、Magota Keiichi、Shiga Tohru、Kuge Yuji、Tamaki Nagara
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 2 Pages: e0213111-e0213111
- DOI
  10.1371/journal.pone.0213111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02757
[Journal Article] Biodistribution and radiation dosimetry of the novel hypoxia PET probe [18F]DiFA and comparison with [18F]FMISO2019
- Author(s)
  Watanabe Shiro、Shiga Tohru、Hirata Kenji、Magota Keiichi、Okamoto Shozo、Toyonaga Takuya、Higashikawa Kei、Yasui Hironobu、Kobayashi Jun、Nishijima Ken-ichi、Iseki Ken、Matsumoto Hiroki、Kuge Yuji、Tamaki Nagara
- Journal Title
  
  EJNMMI Research
  
  Volume: 9 Issue: 1 Pages: 60-60
- DOI
  10.1186/s13550-019-0525-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08180, KAKENHI-PROJECT-17K10428
[Journal Article] Accumulation of hypoxia imaging probe “18F-FMISO” in macrophages depends on macrophage polarization in addition to hypoxic state2019
- Author(s)
  Shimizu Yoichi、Motomura Arata、Takakura Hideo、Tamaki Nagara、Kuge Yuji、Ogawa Mikako
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: in press Issue: 5 Pages: 362-367
- DOI
  10.1007/s12149-019-01332-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19799, KAKENHI-PROJECT-19H03593
[Journal Article] Elimination of tumor hypoxia by eribulin demonstrated by 18F-FMISO hypoxia imaging in human tumor xenograft models2019
- Author(s)
  Zhao S, Yu W, Ukon N, Tan C, Nishijima K, Shimizu Y, Higashikawa K, Shiga T, Yamashita H, Tamaki N, Kuge Y.
- Journal Title
  
  EJNMMI Res
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Journal Article] Erastin, a ferroptosis-inducing agent, sensitized cancer cells to X-ray irradiation via glutathione starvation in vitro and in vivo2019
- Author(s)
  Shibata Yuki、Yasui Hironobu、Higashikawa Kei、Miyamoto Naoki、Kuge Yuji
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 8 Pages: 2826-2836
- DOI
  10.1371/journal.pone.0225931
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04264, KAKENHI-PROJECT-19K10358
[Journal Article] Comparative evaluation of 18F-DiFA and its analogues as novel hypoxia positron emission tomography and 18F-FMISO as the standard.2019
- Author(s)
  Nakata N, Kiriu M, Okumura Y, Zhao S, Nishijima K, Shiga T, Tamaki N, Kuge Y, Matsumoto H.
- Journal Title
  
  Nucl Med Biol
  
  Volume: 70 Pages: 39-45
- DOI
  10.1016/j.nucmedbio.2019.01.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Journal Article] A novel PET probe [18F]DiFA accumulates in hypoxic region via glutathione conjugation following reductive metabolism.2019
- Author(s)
  Shimizu Y, Zhao S, Yasui H, Nishijima K, Matsumoto H, Siga T, Tamaki N, Ogawa M, Kuge Y.
- Journal Title
  
  Mol Imaging Biol
  
  Volume: 21 Issue: 1 Pages: 122-129
- DOI
  10.1007/s11307-018-1214-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Journal Article] Imaging modalities for drug-related osteonecrosis of the jaw (3), Positron emission tomography imaging for the diagnosis of medication-related osteonecrosis of the jaw.2019
- Author(s)
  Kitagawa Y, Ohga N, Asaka T, Sato J, Hata H, Helman J, Tsuboi K, Amizuka N, Kuge Y, Shiga T
- Journal Title
  
  Jpn Dent Sci Rev
  
  Volume: 55 Issue: 1 Pages: 65-70
- DOI
  10.1016/j.jdsr.2018.12.001
- NAID
  50014414221
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05536, KAKENHI-PROJECT-16K11669, KAKENHI-PROJECT-16K11671, KAKENHI-PROJECT-17K11820
[Journal Article] Elimination of tumor hypoxia by eribulin demonstrated by 18F-FMISO hypoxia imaging in human tumor xenograft models2019
- Author(s)
  Zhao Songji、Yu Wenwen、Ukon Naoyuki、Tan Chengbo、Nishijima Ken-ichi、Shimizu Yoichi、Higashikawa Kei、Shiga Tohru、Yamashita Hiroko、Tamaki Nagara、Kuge Yuji
- Journal Title
  
  EJNMMI Research
  
  Volume: 9 Issue: 1 Pages: 51-51
- DOI
  10.1186/s13550-019-0521-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08180, KAKENHI-PROJECT-18H02757
[Journal Article] In vitro uptake and metabolism of [14C]acetate in rabbit atherosclerotic arteries: biological basis for atherosclerosis imaging with [11C]acetate.2018
- Author(s)
  Yamasaki K, Yamashita A, Zhao Y, Shimizu Y, Nishii R, Kawai K, Tamaki N, Zhao S, Asada Y, Kuge Y.
- Journal Title
  
  Nucl Med Biol.
  
  Volume: 56 Pages: 21-25
- DOI
  10.1016/j.nucmedbio.2017.08.003
- NAID
  120006546743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08670, KAKENHI-PROJECT-16K10335, KAKENHI-PROJECT-16H05163, KAKENHI-PROJECT-18K19508
[Journal Article] [18F]DPA-714 PET imaging shows immunomodulatory effect of intravenous administration of bone marrow stromal cells after transient focal ischemia2018
- Author(s)
  Tan C, Zhao S, Higashikawa K, Wang Z, Kawabori M, Abumiya T, Nakayama N, Kazumata K, Ukon N, Yasui H, Tamaki N, Kuge Y, Shichinohe H, Houkin K
- Journal Title
  
  EJNMMI Res
  
  Volume: ８ Issue: 1 Pages: 35-35
- DOI
  10.1186/s13550-018-0392-6
- NAID
  120006482581
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Journal Article] A novel PET probe [18F]DiFA accumulates in hypoxic region via glutathione conjugation following reductive metabolism2018
- Author(s)
  Shimizu Y, Zhao S, Yasui H, Nishijima K, Matsumoto H, Siga T, Tamaki N, Ogawa M, Kuge Y.
- Journal Title
  
  Mol Imaging Biol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10335
[Journal Article] 特集薬剤関連顎骨壊死の画像診断up to date 薬剤関連顎骨壊死のPET検査2018
- Author(s)
  北川善政、浅香卓哉、佐藤　淳秦　浩信、坪井香奈子、網塚憲生、久下裕司、志賀　哲
- Journal Title
  
  臨床放射線
  
  Volume: 63 Issue: 10 Pages: 1071-1081
- DOI
  10.18888/rp.0000000575
- ISSN
  0009-9252
- Year and Date
  2018-10-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05536
[Journal Article] Altered glucose metabolism and hypoxic response in alloxan-induced diabetic atherosclerosis in rabbits.2017
- Author(s)
  Matsuura Y, Yamashita A, Zhao Y, Iwakiri T, Yamasaki K, Sugita C, Koshimoto C, Kitamura K, Kawai K, Tamaki N, Zhao S, Kuge Y, Asada Y.
- Journal Title
  
  PLos One.
  
  Volume: 12(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04898
[Journal Article] Immunoglobulin G (IgG)-based imaging probe accumulates in M1 macrophage-infiltrated atherosclerotic plaques independent of IgG target molecule expression.2017
- Author(s)
  Shimizu Y, Hanzawa H, Zhao Y, Fukura S, Nishijima KI, Sakamoto T, Zhao S, Tamaki N, Ogawa M, Kuge Y.
- Journal Title
  
  Mol Imaging Biol.
  
  Volume: 19(4) Pages: 531-539
- NAID
  120006491485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04898
[Journal Article] 18F-Fluoromisonidazole positron emission tomography (FMISO-PET) may reflect hypoxia and cell proliferation activity in oral squamous cell carcinoma.2017
- Author(s)
  Sato J, Kitagawa Y, Watanabe S, Asaka T, Ohga N, Hirata K, Okamoto S, Shiga T, Shindoh M, Kuge Y, Tamaki N.
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol
  
  Volume: 124(3) Issue: 3 Pages: 261-270
- DOI
  10.1016/j.oooo.2017.05.506
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11820, KAKENHI-PROJECT-16H05536, KAKENHI-PROJECT-15F15420
[Journal Article] Immunoglobulin G (IgG)-Based Imaging Probe Accumulates in M1 Macrophage-Infiltrated Atherosclerotic Plaques Independent of IgG Target Molecule Expression2017
- Author(s)
  Shimizu Yoichi、Hanzawa Hiroko、Zhao Yan、Fukura Sagiri、Nishijima Ken-ichi、Sakamoto Takeshi、Zhao Songji、Tamaki Nagara、Ogawa Mikako、Kuge Yuji
- Journal Title
  
  Mol Imaging Biol
  
  Volume: 19 Issue: 4 Pages: 531-539
- DOI
  10.1007/s11307-016-1036-8
- NAID
  120006491485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293268
[Journal Article] Changes in tumor oxygen states after sorafenib therapy evaluated by 18F-fluoromisonidazole hypoxia imaging in a renal cell cancer xenograft2017
- Author(s)
  Yu W, Zhao S*, Zhao Y, Fatema CN, Murakami M, Nishijima K, Kitagawa Y, Tamaki N, Kuge Y
- Journal Title
  
  Oncol Lett
  
  Volume: 14 Issue: 2 Pages: 2341-2346
- DOI
  10.3892/ol.2017.6371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10335, KAKENHI-PROJECT-15F15420
[Journal Article] Redesign of negatively charged 111In-DTPA-octreotide derivative to reduce renal radioactivity2017
- Author(s)
  Oshima N., Akizawa H., Kawashima H., Zhao S., Zhao Y., Nishijima K. I., Kitamura Y., Arano Y., Kuge Y. and Ohkura K.
- Journal Title
  
  Nuclear medicine and biology
  
  Volume: 48 Pages: 16-25
- DOI
  10.1016/j.nucmedbio.2017.01.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09886, KAKENHI-PROJECT-15K19810, KAKENHI-PROJECT-16K10335
[Journal Article] Recent Advances in the Development of PET/SPECT Probes for Atherosclerosis Imaging2016
- Author(s)
  Shimizu Y, Kuge Y
- Journal Title
  
  Nuclear Medicine and Molecular Imaging
  
  Volume: 50 Issue: 4 Pages: 284-291
- DOI
  10.1007/s13139-016-0418-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293268
[Journal Article] Changes in tumor oxygen state after sorafenib therapy evaluated by 18F-fluoromisonidazole hypoxia imaging of renal cell carcinoma xenograft2016
- Author(s)
  Wenwen Yu, Songji Zhao, Yan Zhao, Chowdhury Nusrat Fatema, Masahiro Murakami, Ken-ichi Nishijima, Yoshimasa Kitagawa, Nagara Tamaki, and Yuji Kuge
- Journal Title
  
  Oncology Letters
  
  Volume: epub
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05536
[Journal Article] Dynamic PET evaluation of elevated FLT level after sorafenib treatment in mice bearing human renal cell carcinoma xenograft.2016
- Author(s)
  Ukon N, Zhao S, Yu W, Shimizu Y, Nishijima KI, Kubo N, Kitagawa Y, Tamaki N, Higashikawa K, Yasui H, Kuge Y
- Journal Title
  
  EJNMMI Res
  
  Volume: 6(1) Issue: 1 Pages: 90-90
- DOI
  10.1186/s13550-016-0246-z
- NAID
  120005972935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05536
[Journal Article] The reoxygenation of hypoxia and the reduction of glucose metabolism in head and neck cancer by fractionated radiotherapy with intensity-modulated radiation therapy.2016
- Author(s)
  Okamoto S, Shiga T, Yasuda K, Watanabe S, Hirata K, Nishijima KI, Magota K, Kasai K, Onimaru R, Tuchiya K, Kuge Y, Shirato H, Tamaki N.
- Journal Title
  
  Eur J Nucl Med Mol Imaging
  
  Volume: 43(12) Issue: 12 Pages: 2147-2154
- DOI
  10.1007/s00259-016-3431-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05536
[Journal Article] The Thymidine Phosphorylase Imaging Agent 123I-IIMU Predicts the Efficacy of Capecitabine.2016
- Author(s)
  Kobashi N, Matsumoto H, Zhao S, Meike S, Okumura Y, Abe T, Akizawa H, Ohkura K, Nishijima K, Tamaki N, Kuge Y.
- Journal Title
  
  Journal of Nuclear Medicine
  
  Volume: 8 Issue: 8 Pages: 1276-1281
- DOI
  10.2967/jnumed.115.165811
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461782
[Journal Article] Combined Plasma and Tissue Proteomic Study of Atherogenic Model Mouse: Approach To Elucidate Molecular Determinants in Atherosclerosis Development.2015
- Author(s)
  Hanzawa H, Sakamoto T, Kaneko A, Manri N, Zhao Y, Zhao S, Tamaki N, Kuge Y
- Journal Title
  
  J Proteome Res.
  
  Volume: 14 Issue: 10 Pages: 4257-4269
- DOI
  10.1021/acs.jproteome.5b00405
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04898
[Journal Article] イメージングによる“がん”の治療効果予測 ―新規核医学診断薬（［123I］IIMU）の臨床研究への歩み―2015
- Author(s)
  久下　裕司，西嶋　剣一，大倉　一枝，志賀　　哲，玉木　長良
- Journal Title
  
  Isotope News
  
  Volume: 1 Pages: 16-20
- Open Access
- Data Source
  KAKENHI-PROJECT-26461782
[Journal Article] Irbesartan Attenuates Atherosclerosis in Watanabe Heritable Hyperlipidemic Rabbits: Noninvasive Imaging of Inflammation by 18F-Fluorodeoxyglucose Positron Emission Tomography.2015
- Author(s)
  Zhao Y, Fukao K, Zhao S, Watanabe A, Yamasaki K, Shimizu Y, Kubo N, Ukon N, Nakano T, Tamaki N, Kuge Y
- Journal Title
  
  Molecular Imaging
  
  Volume: 14 Issue: 5 Pages: 1-8
- DOI
  10.2310/7290.2015.00004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293268
[Journal Article] Relationship between biodistribution of a novel thymidine phosphorylase (TP) probe and TP expression levels in normal mice2015
- Author(s)
  Zhao Ｓ., Li H.,Nishijima K.,,Zhao Y., Akizawa H,,Shimizu Y., Ohkura K., Tamaki N., KugeY.
- Journal Title
  
  Anal.Nucl.Med
  
  Volume: 29 Issue: 7 Pages: 582-587
- DOI
  10.1007/s12149-015-0981-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461802
[Journal Article] Increased metabolite levels of glycolysis and pentose phosphate pathway in rabbit atherosclerotic arteries and hypoxic macrophage2014
- Author(s)
  Atsushi Yamashita, Yan Zhao, Yunosuke Matsuura, Kazuaki Yamasaki, Sayaka Moriguchi-Goto, Chihiro Sugita, Takashi Iwakiri, Nozomi Okuyama, Chihiro Koshimoto, Keiichi Kawai, Nagara Tamaki, Songji Zhao, Yuji Kuge, Yujiro Asada
- Journal Title
  
  PLos One
  
  Volume: 9 Issue: 1 Pages: e86426-e86426
- DOI
  10.1371/journal.pone.0086426
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300158, KAKENHI-PROJECT-23380167, KAKENHI-PROJECT-24659558, KAKENHI-PROJECT-24790354, KAKENHI-PROJECT-25293260, KAKENHI-PROJECT-25460440, KAKENHI-PROJECT-26292170
[Journal Article] Design, synthesis and biological evaluation of negatively charged 111In-DTPA-octreotide derivatives2014
- Author(s)
  Oshima N, Akizawa H, Zhao S, Nishijima K, Kitamura Y, Arano Y, Kuge Y, Ohkura K
- Journal Title
  
  Bioorgan Med Chem
  
  Volume: 22 Issue: 4 Pages: 1377-1382
- DOI
  10.1016/j.bmc.2013.12.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591742, KAKENHI-PROJECT-24591812, KAKENHI-PROJECT-24791329
[Journal Article] Biological characteristics of intratumoral [F-18] fluoromisonidazole distribution in a rodent model of glioma2013
- Author(s)
  Hatano T, Zhao S, Zhao Y, Nishijima K, Kuno N, Hanzawa H, Sakamoto T, Tamaki N, Kuge Y
- Journal Title
  
  Int J Oncol
  
  Volume: 42卷 Issue: 3 Pages: 823-830
- DOI
  10.3892/ijo.2013.1781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-23591742
[Journal Article] Monitoring tumor proliferative response to radiotherapy using (18)F-fluorothymidine in human head and neck cancer xenograft in comparison with Ki-672013
- Author(s)
  Fatema CN, Zhao S, Zhao Y, Murakami M, Yu W, Nishijima KI, Tamaki N, Kitagawa Y, Kuge Y
- Journal Title
  
  Ann Nucl Med
  
  Volume: -
- NAID
  10031176143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Monitoring intratumoral proliferative responses to radiotherapy by 18F-fluorothymidine in a human head and neck cancer xenograft: comparison with Ki-67.2013
- Author(s)
  Fatema CN, Zhao S, Zhao Y, Murakami M, Yu W, Nishijima K, Tamaki N, Kitagawa Y, Kuge Y.
- Journal Title
  
  Ann Nucl Med
  
  Volume: 27 Issue: 4 Pages: 355-362
- DOI
  10.1007/s12149-013-0693-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591742, KAKENHI-PROJECT-25293406
[Journal Article] Arterial 18F-Fluorodeoxyglucose Uptake Reflects Balloon Catheter-Induced Thrombus Formation and Tissue Factor Expression via Nuclear Factor-κB in Rabbit Atherosclerotic Lesions.2013
- Author(s)
  Yamashita A., Zhao Y., Zhao S., Matsuura Y., Sugita C., Iwakiri T., Okuyama N., Ohe K., Koshimoto C., Kawai K., Tamaki N., Kuge Y., Asada Y.
- Journal Title
  
  Circ. J.
  
  Volume: 77(10) Pages: 2626-2635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293260
[Journal Article] Increased intratumoral fluorothymidine uptake levels following multikinase inhibitor sorafenib treatment in a human renal cell carcinoma xenograft model2013
- Author(s)
  Murakami M, Zhao S, Zhao Y, Chowdhury NF, Yu W, Nishijima K, Masahiro Yamasaki, Takiguchi M, Tamaki N, Kuge Y
- Journal Title
  
  Oncology letters
  
  Volume: 6 Issue: 3 Pages: 667-672
- DOI
  10.3892/ol.2013.1459
- NAID
  120005385304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591742
[Journal Article] Pathophysiological characteristics of melanoma in-transit metastasis in a lymphedema mouse model2013
- Author(s)
  Oashi, K., Furukawa, H., Nishihara, H., Ozaki, M., Oyama, A., Funayama, E., Hayashi, T., Kuge, Y., Yamamoto, Y
- Journal Title
  
  J Invest Dermatol
  
  Volume: 133 (2) Pages: 537-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390330
[Journal Article] Increased intratumoral fluorothymidine (FLT) uptake level after multikinase inhibitor sorafenib treatment in a human renal cell carcinoma xenograft.2013
- Author(s)
  Murakami M, Zhao S, Zhao Y, Chowdhury NF, Yu W, Nishijima K, Masahiro Yamasaki, Takiguchi M, Tamaki N, Kuge Y.
- Journal Title
  
  Oncology letters
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591742
[Journal Article] High reproducibility of tumor hypoxia evaluated by18F-fluoromisonidazole PET for head and neck cancer2013
- Author(s)
  Okamoto S, Shiga T, Yasuda K, Ito YM, Magota K, Kasai K, Kuge Y, Shirato H, Tamaki N
- Journal Title
  
  J Nucl Med
  
  Volume: 54 Issue: 2 Pages: 201-207
- DOI
  10.2967/jnumed.112.109330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-23591744
[Journal Article] Reoxygenation-induced nitric oxide mitigates tumor hypoxia and radioresistance in a murine SCCVII tumor model2013
- Author(s)
  Nagane M, Yasui H, Yamamori T, Zhao S, Kuge Y, Tamaki N, Kameya H, Nakamura H, Fujii H, Hirata H, Inanami O
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 437 Issue: 3 Pages: 420-425
- DOI
  10.1016/j.bbrc.2013.06.093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591742, KAKENHI-PROJECT-24654112, KAKENHI-PROJECT-24659551, KAKENHI-PROJECT-25861045
[Journal Article] Assessment of early changes in 3H-fluorothymidine uptake after treatment with gefitinib in human tumor xenograft in comparison with Ki-67 and phospho-EGFR expression2013
- Author(s)
  Zhao S, Kuge Y, Zhao Y, Takeuchi S, Hirata K, Takei T, Shiga T, Dsaka-Akita H and Tamaki N
- Journal Title
  
  BMC Cancer
  
  Volume: 13 Issue: 1 Pages: 525-525
- DOI
  10.1186/1471-2407-13-525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591742
[Journal Article] Evaluation of changes in the tumor microenvironment after sorafenib therapy by sequential histology and 18F-fluoromisonidazole hypoxia imaging in renal cell carcinoma2012
- Author(s)
  Murakami M, Zhao S, Zhao Y, Chowdhury NF, Yu W, Nishijima K, Takiguchi M, Tamaki N, Kuge Y
- Journal Title
  
  Int J Oncol
  
  Volume: 41卷 Issue: 5 Pages: 1593-1600
- DOI
  10.3892/ijo.2012.1624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-23591742
[Journal Article] 18F-Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas2012
- Author(s)
  Hirata K, Terasaka S, Shiga T, Hattori N, Magota K, Kobayashi H, Yamaguchi S, Houkin K, Tanaka S, Kuge Y, Tamaki N
- Journal Title
  
  Eur J Nucl Med Mol Imaging
  
  Volume: (In press) Issue: 5 Pages: 760-770
- DOI
  10.1007/s00259-011-2037-0
- NAID
  120005228670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] 医薬品開発（又は創薬・育薬）における分子イメージング技術の現状と進歩2012
- Author(s)
  久下裕司、西嶋剣一、孫田恵一、趙松吉、玉木長良
- Journal Title
  
  医薬品医療機器レギュラトリーサイエンス
  
  Volume: 43 Pages: 308-313
- Data Source
  KAKENHI-PROJECT-23591742
[Journal Article] 医薬品開発（又は創薬・育薬）における分子イメージング技術の現状と進歩2012
- Author(s)
  久下裕司、西嶋剣一、孫田恵一、趙松吉、玉木長良
- Journal Title
  
  医薬品医療機器レギュラトリーサイエンス
  
  Volume: 43卷 Pages: 308-313
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Dynamic 11 C-methionine PET analysis has an additional value for differentiating malignant tumors from granulomas : an experimental study using small animal PET2011
- Author(s)
  Zhao S, Kuge Y, Yi M, Zhao Y, Hatano T, Magota K, Nishijima K, Kohanawa M, Tamaki N
- Journal Title
  
  Eur J Nucl Med Mol Imaging
  
  Volume: 38 Issue: 10 Pages: 1876-1886
- DOI
  10.1007/s00259-011-1865-2
- NAID
  120004710960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-23591742
[Journal Article] Raiolabeled uracil derivatives as a novel SPECT probe for thymidine phosphorylase suppresses accumulation into tumor cells by target gene knockdown2011
- Author(s)
  Li H., Zhao S., Jin Y., Nishijima K., Akizawa H., Ohkura K., Tamaki N., Kuge Y
- Journal Title
  
  Nucl. Med. Commun
  
  Volume: 32 Pages: 1211-1215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591826
[Journal Article] Localization of deoxyglucose and annexin A5 in experimental atheroma correlates with macrophage infiltration but not lipid deposition in the lesion.2011
- Author(s)
  Zhao Y, Zhao S, Kuge Y, Strauss WH, Blankenberg FG, Tamaki N.
- Journal Title
  
  Mol Imaging Biol. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390321
[Journal Article] Performance characterization of the Inveon preclinical small-animal PET/SPECT/CT system for multimodality imagine2011
- Author(s)
  Magota K, Kubo N, Kuge Y, Nishijima K, Zhao S, Tamaki N
- Journal Title
  
  Eur J Nucl Med Mol Imaging
  
  Volume: 38 Issue: 4 Pages: 742-752
- DOI
  10.1007/s00259-010-1683-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] ^<18>F-Fluorothymidine PET/CT as an early predictor of tumor response to treatment with cetuximab in human lung cancer xenografts2011
- Author(s)
  Takeuchi S, Zhao S, Kuge Y, Zhao Y, Nishijima K, Hatano T, Shimizu Y, Kinoshita I, Tamaki N, Dosaka-Akita H
- Journal Title
  
  Oncol Rep
  
  Volume: 26 Pages: 725-730
- DOI
  10.3892/or.2011.1338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591742
[Journal Article] アポートーシスイメージングプローブ2011
- Author(s)
  久下裕司、竹井俊樹、趙松吉
- Journal Title
  
  PET Journal
  
  Volume: No.13 Pages: 23-25
- Data Source
  KAKENHI-PROJECT-21591539
[Journal Article] Semiquantitative analysis of C-11 methionine PET may distinguish brain tumor recurrence from radiation necrosis even in small lesions2011
- Author(s)
  Okamoto S, Shiga T, Hattori N, Kubo N, Takei T, Katoh N, Sawamura Y, Nishijima K, Kuge Y, Tamaki N
- Journal Title
  
  Ann Nuci Med
  
  Volume: 25 Issue: 3 Pages: 213-220
- DOI
  10.1007/s12149-010-0450-2
- NAID
  10028999449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Semiquantitative analysis of C-11 methionine PET may distinguish brain tumor recurrence from radiation necrosis even in small lesions.2011
- Author(s)
  Okamoto S, Shiga T, Hattori N, Kubo N, Takei T, Katoh N, Sawamura Y, Nishijima,K, Kuge Y, Tamaki N.
- Journal Title
  
  Ann Nucl Med. 25(3)
  
  Pages: 213-20
- NAID
  10028999449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591429
[Journal Article] Radiolabeled uracil derivative as a novel SPECT probe for thymidine phosphorylase : suppressed accumulation into tumor cells by target gene knockdown2011
- Author(s)
  Li H, Zhao S, Jin Y, Nishijima K, Akizawa H, Ohkura K, Tamaki N, Kuge Y
- Journal Title
  
  Nucl Med Commun
  
  Volume: 32 Issue: 12 Pages: 1211-1215
- DOI
  10.1097/mnm.0b013e32834b7ea7
- NAID
  120004979488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591742, KAKENHI-PROJECT-23591811, KAKENHI-PROJECT-23591826
[Journal Article] Semiquantitative analysis of C-11 methionine PET may distinguish brain tumor recurrence from radiation necrosis even in small lesions2011
- Author(s)
  Okamoto S, Shiga T, Hattori N, Kubo N, Takei T, Katoh N, Sawamura Y, Nishijima K, Kuge Y, Tamaki N
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 25(3) Pages: 213-220
- NAID
  10028999449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591429
[Journal Article] Molecular Imaging for the Assessment of Tumor Malignancy and Response to Therapy. 20102010
- Author(s)
  Kuge Y, et al.
- Journal Title
  
  Springer Science+Business Media, Heidelberger(Tamaki N, Kuge Y eds.)(Springer)
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] In vitro and in vivo evaluations of a radioiodinated thymidine phosphorylase inhibitor as a tumor diagnostic agent for angiogenic enzyme imaging.2010
- Author(s)
  Akizawa H, Zhao S, Takahashi M, Nishijima K, Kuge Y, Tamaki N, Seki K, Ohkura K.
- Journal Title
  
  Nucl Med Biol. 37(4)
  
  Pages: 427-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390321
[Journal Article] Molecular imaging of apoptosis with Radio-Labeled Annexin A5 focused on the evaluation of tumor response to chemotherapy.2010
- Author(s)
  Kuge Y
- Journal Title
  
  Anti-Cancer Agents in Medicinal Chemistry (9)
  
  Pages: 1003-1011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390321
[Journal Article]2010
- Author(s)
  Kuge Y, et al.
- Journal Title
  
  Molecular Imaging for the Assessment of Tumor Malignancy and Response to Therapy. In : Molecular Imaging for Integrated Medical Therapy and Drug Development(Tamaki N, kuge Y, eds.)(Springer(Springer Science+Business Media), Heidelberger Kuge Y et al.)
- Data Source
  KAKENHI-PROJECT-20390320
[Journal Article] In vitro and in vivo evaluations of a radioiodinated thymidine phosphorylase inhibitor as a tumor diagnostic agent for angiogenic enzyme imaging.2010
- Author(s)
  Akizawa H, Zhao S, Takahashi M, Nishijima K, Kuge Y, Tamaki N, Seki K, Ohkura K
- Journal Title
  
  Nucl Med Biol. 37
  
  Pages: 427-432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390320
[Journal Article] Synthesis and evaluation of a radioiodinated lumiracoxib derivative for the imaging of cyclooxygenase-2 expression2009
- Author(s)
  Kuge Y, Obokata N, Kimura H, et al.
- Journal Title
  
  Nuclear Medicine and Biology 36
  
  Pages: 869-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] Molecular Imaging of Apoptosis with Radio-Labeled Annexin A5 Focused on the Evaluation of Tumor Response to Chemotherapy.2009
- Author(s)
  Kuge Y, Zhao S, Takei T, Tamaki N.
- Journal Title
  
  Anti-Cancer Agents in Medicinal Chemistry. 9
  
  Pages: 1003-1011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390320
[Journal Article] Molecular Imaging of Apoptosis with Radio-Labeled Annexin A5 Focused on the Evaluation of Tumor Response to Chemotherapy2009
- Author(s)
  Kuge Y, et al.
- Journal Title
  
  Anti-Cancer Agents in Medicinal Chemistry 9
  
  Pages: 1003-1011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390320
[Journal Article] Synthesis and evaluation of a radioiodinated lumiracoxib derivative for the imaging of cyclooxygenase-2 expression.2009
- Author(s)
  Kuge Y, Obokata N, Kimura H, Katada Y, Temma T, Suginoto Y, Aita K, Seki K, Tamaki N, Saji H
- Journal Title
  
  Nucl Med Biol 36(8)
  
  Pages: 869-876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390321
[Journal Article] New [^<11>C] phosgene based synthesis of [^<11>C] pyrimidines for positron emission tomography2009
- Author(s)
  Seki K., Nishijima K., Sanoki K., Kuge Y., Takahashi M., Akizawa H., Tamaki N., Wiebe LI., Ohkura K.
- Journal Title
  
  Heterocycles 77
  
  Pages: 1307-1321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591457
[Journal Article] Synthesis and evaluation of a radioiodinated Lumiracoxib derivative for the imaging of cyclooxygenase-2 expression.2009
- Author(s)
  Kuge Y, et al.
- Journal Title
  
  Nucl Med Biol. 36(8)
  
  Pages: 869-876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Clinical value and limitations of 11C-methionine PET for detection and localization of suspected parathyroid adenomas2009
- Author(s)
  Hermann K, Takei T, Kanegae K, Shiga T, Buck AK, Altomonte J, Schwaiger M, Schuster T, Nishijima K, Kuge Y, Tamaki N
- Journal Title
  
  Mol Imaging Biol 11(5)
  
  Pages: 356-363
- NAID
  120002383243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Synthesis and evaluation of a radioiodinated Lumiracoxib derivative for the imaging of cyclooxygenase-2 expression.2009
- Author(s)
  Kuge Y, et al.
- Journal Title
  
  Nucl Med Biol. 36(8)
  
  Pages: 869-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390320
[Journal Article] Synthesis and evaluation of a radioiodinated lumiracoxib derivative for the imaging of cyclooxygenase-2 expression2009
- Author(s)
  Kuge Y, Obokata N, Kimura H, Saji H, et al.
- Journal Title
  
  Nuclear Medicine and Biology Vol.36
  
  Pages: 869-876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] New [11C] phosgene based synthesis of [11C]- pyrimidines for positron emission tomography2009
- Author(s)
  Seki K., Nishijima K., Sanoki K., Kuge Y., Takahashi M., Akizawa H., Tamaki N., Wiebe LI., Ohkura K.
- Journal Title
  
  Heterocycles 77
  
  Pages: 1307-1321
- Data Source
  KAKENHI-PROJECT-20591457
[Journal Article] Development of PET/SPECT probes for radiotherapy: Focused on hypoxia imaging.2008
- Author(s)
  Kuge Y, et. al.
- Journal Title
  
  Japanese Journal of Cancer Clinics 54(2)
  
  Pages: 105-108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390332
[Journal Article] Prominent lectin-like oxidized low density lipoprotein (LDL) receptor-1 (LOX-1) expression in atherosclerotic lesions is associated with tissue factor expression and apoptosis in hypercholesterolemic rabbits.2008
- Author(s)
  Kuge Y, et al.
- Journal Title
  
  Biol Pharm Bull 31
  
  Pages: 1475-82
- NAID
  110006839004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659311
[Journal Article] 放射線治療を指向したPET/SPECTプローブの開発〜低酸素イメージングを中心に〜。2008
- Author(s)
  久下裕司, 他。
- Journal Title
  
  癌の臨床 54(2)
  
  Pages: 105-108
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390332
[Journal Article] Synthesis of 11C-labeled uracil derivative for a pet tracer targeting thymidine phosphorylase2008
- Author(s)
  Takahashi M., Seki K., Nishijima K., Kuge Y., Tamaki N., Ohkura K.
- Journal Title
  
  Hetero- cycles 76
  
  Pages: 237-241
- Data Source
  KAKENHI-PROJECT-20591457
[Journal Article] 11C-methionine, not 18F-FDG or 18F-FLT can differentiate tumors from granulomas in experimental rat models.2008
- Author(s)
  Zhao S, Kuge Y, Kohanawa M, Takahashi T, Zhao Y, Yi M, Kanegae K, Seki KI, Tamaki N
- Journal Title
  
  J Nucl Med 49(1)
  
  Pages: 135-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209039
[Journal Article] Usefulness of ^<11>C-methionine for differentiating tumors from granulomas in experimental rat models : a comparison with ^<18>F-FDG and ^<18>F-FLT.2008
- Author(s)
  Zhao S, Kuge Y, Kohanawa M, Takahashi T, Zhao Y, Yi M, Kanegae K, Seki KI, Tamaki N
- Journal Title
  
  J Nucl Med 49(1)
  
  Pages: 135-141
- NAID
  120003118186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390321
[Journal Article] 11C-methionine, not 18F-FDG or 18F-FLT can differentiate tumors from granulomas in experimental rat models2008
- Author(s)
  Zhao S, Kuge Y, Kohanawa M, Takahashi T, Zhao Y, Yi M, Kanegae K, Seki KI, Tamaki N
- Journal Title
  
  J Nucl Med 49(1)
  
  Pages: 135-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209039
[Journal Article] Synthesis of ^<11>C-labeled uracil derivative for a pet tracer targeting thymidine phosphorylase.2008
- Author(s)
  Takahashi M., Seki K., Nishijima K., Kuge Y., Tamaki N., Ohkura K.
- Journal Title
  
  Heterocycles 76
  
  Pages: 237-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591457
[Journal Article] Prolonged high-fat feeding enhances aortic ^<18>F-FDG and ^<99m>Tc-annexin A5 uptake in apolipoprotein E-deficient and wild-type C57BL/6J mice.2008
- Author(s)
  Zhao Y, Kuge Y, Zhao S, Strauss HW, Blankenberg FG, Tamaki N
- Journal Title
  
  J Nucl Med 49(10)
  
  Pages: 1707-14
- NAID
  120003118185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390321
[Journal Article] (99m)Tc-Annexin A5 for noninvasive characterization of atherosclerotic lesions : imaging and histological studies in myocardial infarction-prone Watanabe heritable hyperlipidemic rabbits.2007
- Author(s)
  S Ishino, Y Kuge, N Takai, N Tamaki, SH W trauss, FG Blankenberg, M Shiomi, H.Saji
- Journal Title
  
  Eur. J. Nucl. Med., Mol Imaging 34(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] Molecular imaging and strategies for cancer treatment: A Study to achieve noninvasive in vivo pathological evaluation by molecular imaging.2007
- Author(s)
  Kuge Y, et. al.
- Journal Title
  
  INNERVISION 22(7)
  
  Pages: 42-42
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390332
[Journal Article] Comparison of (99m)Tc-annexin A5 with (18)F-FDG for the detection of atherosclerosis in ApoE-/- mice.2007
- Author(s)
  Yuji Kuge
- Journal Title
  
  Eur J Nucl Med Mol Imaging 34(印刷中)
- NAID
  120000955826
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] A novel and efficient synthesis of [2-11C]5-fluorouracil for prognosis of cancer chemotherapy.2007
- Author(s)
  Seki K, Nishijima K, Kuge Y, Tamaki N, Wiebe LI, Ohkura K
- Journal Title
  
  J Pharm Pharmaceut Sci. 10(2)
  
  Pages: 181-185
- Data Source
  KAKENHI-PROJECT-17390332
[Journal Article] Distribution Profiles of Membrane Type-1 Matrix Metalloproteinase (MT1-MMP), Matrix Metalloproteinase-2 (MMP-2) and Cyclooxygenase-2 (COX-2) in Rabbit Atherosclerosis: Comparison with Plaque Instability Analysis.2007
- Author(s)
  Kuge Y, et. al.
- Journal Title
  
  Biol Pharm Bull 30
  
  Pages: 1634-40
- NAID
  110006380241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659311
[Journal Article] ^<99m>Tc-Annexin A5 for noninvasive characterization of atherosclerotic lesions : imaging and histological studies in myocardial infarction-prone Watanabe heritable hyperlipidemic rabbits.2007
- Author(s)
  Ishino S, Kuge Y, Takai N, Tamaki N, Strauss HW, Blankenberg FG, Shiomi M, Saji H.
- Journal Title
  
  Eur J Nucl Med Mol Imaging. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] A novel and efficient synthesis of [2-11C]5-fluorouracil for prognosis of cancer chemotherapy.2007
- Author(s)
  Seki K, Nishijima K, Kuge Y, Tamaki N, Wiebe LI, Ohkura K
- Journal Title
  
  J Pharm Pharmaceut Sci. 10(2)
  
  Pages: 181-185
- Data Source
  KAKENHI-PROJECT-18659345
[Journal Article] Lectin-like oxidized LDL receptor-1 (LOX-1) expression is associated with atherosclerotic plaque instability-analysis in hypercholesterolemic rabbits.2007
- Author(s)
  S.Ishino, T.Mukai, N.Kume, D.Asano, M.Ogawa, Y.Kuge, M.Minami, T.Kita, M.Shiomi, H.Saji.
- Journal Title
  
  Atherosclerosis (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] 分子イメージングとがん治療戦略:イメージングによるインビボ組織染色を目指して。2007
- Author(s)
  久下裕司, 他。
- Journal Title
  
  INNERVISION. 22(7)
  
  Pages: 42-42
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390332
[Journal Article] Lectin-like oxidized LDL receptor-1 (LOX-1) expression is associated with atherosclerotic plaque instability-analysis in hypercholesterolemic rabbits.2007
- Author(s)
  Ishino S, Mukai T, Kume N, Asano D, Ogawa M, Kuge Y, Minami M, Kita T, Shiomi M, Saji H.
- Journal Title
  
  Atherosclerosis. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] A new convenient method for the synthesis of [2-11C]thymine utilizing [11C]phosgene.2006
- Author(s)
  Ohkura K, Nishijima K, Sanoki K, Kuge Y, Tamaki N, Seki K
- Journal Title
  
  Tetrahedron Letters 47
  
  Pages: 5321-5323
- Data Source
  KAKENHI-PROJECT-18659345
[Journal Article] Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression2006
- Author(s)
  Kuge Y, Katada Y, Simonaka S, Temma T, Kimura H, Kiyono Y, Yokota C, Minematsu K, Seki K, Tamaki N, Ohkura K, Saji H
- Journal Title
  
  Nuclear Medicine and Biology 33
  
  Pages: 21-27
- Data Source
  KAKENHI-PROJECT-18591619
[Journal Article] Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression.2006
- Author(s)
  Kuge Y et al.
- Journal Title
  
  Nucl Med Biol 33(1)
  
  Pages: 21-27
- Data Source
  KAKENHI-PROJECT-16659315
[Journal Article] A new convenient method for the synthesis of [2-11C]thymine utilizing [11C]phosgene.2006
- Author(s)
  Ohkura K, Nishijima K, Sanoki K, Kuge Y, Tamaki N, Seki K
- Journal Title
  
  Tetrahedron Letters. 47
  
  Pages: 5321-5323
- Data Source
  KAKENHI-PROJECT-17390332
[Journal Article] Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression.2006
- Author(s)
  Kuge, Y., et al.
- Journal Title
  
  Nucl Med Biol 33・1
  
  Pages: 21-27
- Data Source
  KAKENHI-PROJECT-18209039
[Journal Article] Photochemical synthesis of polycyclic pyrimidines through the acid catalyzed cycloaddition of 6-chloro-1-methyluracil to methyl substituted bezenes.2006
- Author(s)
  Ohkura K, Yamaguchi T, Nishijima K, Kuge Y, Seki K
- Journal Title
  
  Heterocycles 70
  
  Pages: 501-508
- Data Source
  KAKENHI-PROJECT-18659345
[Journal Article] Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression2006
- Author(s)
  Kuge Y, Katada Y, Simonaka S, Temma T, Kimura Y, Kiyono Y, Yokota C, Minematsu K, Seki K, Tamaki N, Ohkura K, Saiji H
- Journal Title
  
  Nucl Med and Biology 33
  
  Pages: 21-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591559
[Journal Article] Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression.2006
- Author(s)
  Kuge Y et al.
- Journal Title
  
  Nucl Med Biol. 33(1)
  
  Pages: 21-27
- Data Source
  KAKENHI-PROJECT-17390332
[Journal Article] Photochemical synthesis of polycyclic pyrimidines through the acid catalyzed cycloaddition of 6-chloro-1-methyluracil to methyl substituted bezenes.2006
- Author(s)
  Ohkura K, Yamaguchi T, Nishijima K, Kuge Y, Seki K
- Journal Title
  
  Heterocycles. 70
  
  Pages: 501-508
- Data Source
  KAKENHI-PROJECT-17390332
[Journal Article] Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression2006
- Author(s)
  Kuge Y, Katada Y, Simonaka S, Temma T, Kimura H, Kiyono Y, Yokota C, Minematsu K, Seki K, Tamaki N, Ohkura K, Saji H
- Journal Title
  
  Nucl Med and Biology 33
  
  Pages: 21-27
- Data Source
  KAKENHI-PROJECT-18591619
[Journal Article] Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression.2006
- Author(s)
  Kuge Y , et. al.
- Journal Title
  
  Nucl Med Biol. 33(1)
  
  Pages: 21-27
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390332
[Journal Article] Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression,2006
- Author(s)
  Kuge Y, Katada Y, Simonaka S, Temma T, Kimura Y, Kiyono Y, Yokota C, Minematsu K, Seki K, Tamaki N, Ohkura K, Saiji H
- Journal Title
  
  Nucl Med and Biology 33
  
  Pages: 21-27
- Data Source
  KAKENHI-PROJECT-15591559
[Journal Article] Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression.2006
- Author(s)
  Kuge Y , et. al.
- Journal Title
  
  Nucl Med Biol 33(1)
  
  Pages: 21-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390332
[Journal Article] Aggravation of hemorrhagic transformation by early intraarterial infusion of low-dose vascular endothelial growth factor after transient focal cerebral ischemia in rats2005
- Author(s)
  Abumiya T, Yokota C, Kuge Y, Minematsu K
- Journal Title
  
  Brain Research 1049
  
  Pages: 95-103
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591559
[Journal Article] 99m-Tc-Annexin 5 for noninvasive characterization of atherosclerotic lesions : imaging and histological studies in Watanabe heritavle2005
- Author(s)
  Yuji Kuge
- Journal Title
  
  J.Nucl.Med. 46・S2
- Data Source
  KAKENHI-PROJECT-16390337
[Journal Article] Bilateral induction of the S-100A9 gene in response to spreading detiression is modulated by the cyclooxygenase-2 activity2005
- Author(s)
  Yokota C, Kuge Y, Inoue H, Tamaki N, Minematsu K
- Journal Title
  
  Journal of the Neurological Sciences 234
  
  Pages: 11-16
- Data Source
  KAKENHI-PROJECT-15591559
[Journal Article] Bilateral induction of the S-100A9 gene in response to spreading depression is modulated by the cyclooxygenase-2 activity2005
- Author(s)
  Yokota C, Kuge Y, Inoue H, Tamaki N, Minematsu K
- Journal Title
  
  Journal of the Neurological Sciences 234
  
  Pages: 11-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591559
[Journal Article] Aggravation of hemorrhagic transformation by early intraarterial infusion of low-close vascular endothelial growth factor after transient focal cerebral ischemia in rats2005
- Author(s)
  Abumiya T, Yokota C, Kuge Y, Minematsu K
- Journal Title
  
  Brain Research 1049
  
  Pages: 95-103
- Data Source
  KAKENHI-PROJECT-15591559
[Journal Article] Feasibility of 99mTc-annexin V for repetitive detection of apoptotic tumor response to chemotherapy : an experimental study using a rat tumor model.2004
- Author(s)
  Kuge T
- Journal Title
  
  J Nucl Med 45(2)
  
  Pages: 309-312
- Data Source
  KAKENHI-PROJECT-14370265
[Journal Article] Feasibility of ^<99m>Tc-annexin V for repetitive detection of apoptotic tumor response to chemotherapy : An experimental study using a rat tumor model.2004
- Author(s)
  Kuge Y
- Journal Title
  
  J Nucl Med 45(2)
  
  Pages: 309-312
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370265
[Journal Article] Temporal and topographic profiles of cyclooxygenase-2 expression during 24 hours of focal brain ischemia in rats.2004
- Author(s)
  Yokota C, Kaji T, Kuge Y, Inoue H, Tamaki N, Minematsu K
- Journal Title
  
  Neuroscience Letters 357
  
  Pages: 219-222
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591559
[Journal Article] Characterisation of [^<123>I] iomazenil distribution in a rat model ofocal cerebral ischaemia in relation to histopathological findings2004
- Author(s)
  Kaji T, Kuge Y, Yokota C, Tagaya M, Inoue H, Shiga T, Minematsu K, Tamaki N
- Journal Title
  
  European Journal of Nuclear Medicine and Molecular Imaging 31
  
  Pages: 64-70
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591559
[Journal Article] Post-ischemic cyclooxygenase-2 expression is regulated by the extent of cerebral blood flow reduction in non-human primates2003
- Author(s)
  Yokota C, Kuge Y, Inoue H, Tagaya M, Kite G, Susumu T, Tamaki N, Minematsu K
- Journal Title
  
  Neuroscience Letters 341
  
  Pages: 37-40
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591559
[Journal Article] Characteristic brain distribution of [1-^<14>C]octanoate in a rat model of focal cerebral ischemia in comparison with those of [^<123>I]IMP and [^<123>I]iomazenil.2003
- Author(s)
  Kuge Y et al.
- Journal Title
  
  J Nucl Med 44-7
  
  Pages: 1168-1175
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370266
[Journal Article] Cyclooxygenase-2 expression associated with spreading depression in a primate model.2003
- Author(s)
  Yokota C, Inoue H, Kuge Y, Abumiya T, Tagaya M, Hasegawa Y, Ejima N, Tamaki N, Minematsu K
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism 23
  
  Pages: 395-398
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591559
[Journal Article] Characteristic Brain Distribution of [1-^<14>C]Octanoate in a Rat Model of Focal Cerebral Ischemia in Comparison with Those of [^<123>I]IMP and [^<123>I]Iomazenil.2003
- Author(s)
  Kuge Y 他
- Journal Title
  
  J Nucl Med. 44(7)
  
  Pages: 1168-1175
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370266
[Journal Article] Chemical impurities in [^<18>F]FDG preparations produced by solid-phase ^<18>F-fluorination.2002
- Author(s)
  Kuge Y
- Journal Title
  
  Nucl Med Biol 29(2)
  
  Pages: 275-279
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370265
[Journal Article] Arterial 18F-fluorodeoxyglucose uptake reflects thrombus formation and tissue factor expression via nuclear factor-κB in rabbit atherosclerotic lesions
- Author(s)
  Atsushi Yamashita, Yan Zhao, Songji Zhao, Yunosuke Matsuura, Chihiro Sugita, Takashi Iwakiri, Nozomi Okuyama, Kazuyo Ohe, Chihiro Koshimoto, Keiichi Kawai, Nagara Tamaki, Yuji Kuge, and Yujiro Asada
- Journal Title
  
  Circulation Journal
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-23659573
[Journal Article] Performance characterization of the Inveon preclinical small-animal PET/SPECT/CT system for multimodality imaging.
- Author(s)
  Magota K, Kubo N, Kuge Y, Nishijima K, Zhao S, Tamaki N
- Journal Title
  
  Eur J Nucl Med Mol Imaging. (印刷中)
- NAID
  120003918916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390320
[Journal Article] Semiquantitative analysis of C-11 methionine PET may distinguish brain tumor recurrence from radiation necrosis even in small lesions.
- Author(s)
  Okamoto S, Shiga T, Hattori N, Kubo N, Takei T, Katoh N, Sawamura Y, Nishijima K, Kuge Y, Tamaki N
- Journal Title
  
  Ann Nucl Med. (印刷中)
- NAID
  10028999449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390320
[Patent] 18Ｆ標識放射性化合物の製造における効率的な18Ｆ化法2018
- Inventor(s)
  久下裕司, 阿保憲史, 桐生真登
- Industrial Property Rights Holder
  日本メジフィジックス
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-155850
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K19640
[Patent] 無水18Ｆ精製溶液による放射性核種18Ｆの精製法2018
- Inventor(s)
  久下裕司, 阿保憲史, 平田雄一
- Industrial Property Rights Holder
  北海道大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-163034
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K19640
[Patent] ウラシル化合物又はその塩、これらを有効成分として含有するイメージング剤、およびこれらを有効成分として含有する腫瘍診断をするためのイメージング剤2012
- Inventor(s)
  発明者:大倉一枝、関興一、西嶋剣一、高橋正幸、久下裕司、玉木長良、趙松吉
- Industrial Property Rights Holder
  国立大学法人北海道大学学校法人東日本学園・北海道医療大学
- Industrial Property Rights Type
  特許
- Acquisition Date
  2012-01-18
- Overseas
- Data Source
  KAKENHI-PROJECT-23591826
[Patent] ウラシル化合物又はその塩、これらを有効成分として含有するイメージング剤、およびこれらを有効成分として含有する腫瘍診断をするためのイメージング剤2007
- Inventor(s)
  大倉一枝、関興一、西嶋剣一、高橋正幸、久下裕司、玉木長良、趙松吉
- Industrial Property Rights Holder
  大倉一枝、関興一、西嶋剣一、高橋正幸、久下裕司、玉木長良、趙松吉
- Industrial Property Number
  2007-229002
- Filing Date
  2007-09-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390332
[Presentation] Synthesis of [64Cu]Cu+ complex for redox imaging and evaluation of its reactivity with reactive oxygen species.2023
- Author(s)
  Tada T, Mizuno Y, Shibata Y, Yasui H, Kuge Y
- Organizer
  The 25th International Symposium of Radiopharmaceutical Sciences (iSRS 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19433
[Presentation] Cystine-dense peptide TfRB1G3 のTfR1への親和性評価と68Ga標識に向けたHBED-CC結合体の合成2023
- Author(s)
  林龍昕、水野雄貴、久下裕司、柴田悠貴、安井博宣
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K19433
[Presentation] The synthesis and evaluation of [68Ga]Ga-HBED-CC-TfRB1G3 for TfR1 imaging.2023
- Author(s)
  Lin L., Mizuno Y., Shibata Y., Yasui H., Kuge Y.
- Organizer
  The 25th International Symposium on Radiopharmaceutical Sciences (ISRS2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24994
[Presentation] Cystine-dense peptide TfRB1G3 のTfR1への親和性評価と68Ga標識に向けたHBED-CC結合体の合成2023
- Author(s)
  林龍昕、水野雄貴、久下裕司、柴田悠貴、安井博宣
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K21417
[Presentation] The synthesis and evaluation of [68Ga]Ga-HBED-CC-TfRB1G3 for TfR1 imaging.2023
- Author(s)
  Lin L, Mizuno Y, Shibata Y, Yasui H, Kuge Y
- Organizer
  The 25th International Symposium of Radiopharmaceutical Sciences (iSRS 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K21417
[Presentation] Synthesis of [64Cu]Cu+ complex for redox imaging and evaluation of its reactivity with reactive oxygen species2023
- Author(s)
  Tada T., Mizuno Y., Shibata Y., Yasui H., Kuge Y.
- Organizer
  The 25th International Symposium on Radiopharmaceutical Sciences (ISRS2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24994
[Presentation] Redox imaging of tumors with a novel compact and portable EPRI device and its potential for multimodal imaging2023
- Author(s)
  Kato K., Yasui H., Sato-Akaba H., Emoto MC., Fujii HG., Mizuno Y., Kuge Y., Nagane M., Yamashita T., Inanami O.
- Organizer
  The Annual Meeting of the Society for Free Radical Biology and Medicine 2023 & SFRRI 21st Biennial Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24994
[Presentation] 18F-FDG PET/MRI によるマウス網膜変性疾患モデルの評価2023
- Author(s)
  松元慎吾，須藤志保，安井博宣，水野雄貴，久下裕司，山田健一，平田拓
- Organizer
  第17 回日本分子イメージング学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-23K18259
[Presentation] ROSイメージングを目的とした[64Cu]Cu+錯体の合成と評価：配位子構造が錯体の安定性に与える影響2022
- Author(s)
  多田哲朗、水野雄貴、柴田悠貴、安井博宣、久下裕司
- Organizer
  第62回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K19433
[Presentation] Cystine-dense peptideを母体としたTfR1イメージング薬剤開発に向けた基礎的検討2022
- Author(s)
  林龍昕、水野雄貴、柴田悠貴、安井博宣、久下裕司
- Organizer
  第8回北大・部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19433
[Presentation] ROSイメージングを目的としたメタボリックトラップ型PETプローブの開発：CuI-BCA錯体の利用2022
- Author(s)
  多田哲朗, 水野雄貴, 柴田悠貴, 安井博宣, 久下裕司
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K19433
[Presentation] トランスフェリン受容体認識直鎖ペプチドを母体とした68Ga標識プローブの合成と評価2022
- Author(s)
  水野雄貴, 三浦春香, 安井博宣, 柴田悠貴, 大久保直登, 前原経, 武田宏司, 大西俊介, 久下裕司
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-23K21417
[Presentation] トランスフェリン受容体認識直鎖ペプチドを母体とした68Ga標識プローブの合成と評価2022
- Author(s)
  水野雄貴, 三浦春香, 安井博宣, 柴田悠貴, 大久保直登, 前原経, 武田宏司, 大西俊介, 久下裕司
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K19433
[Presentation] トランスポーター高発現細胞を用いたチミジンホスホリラーゼ標的放射性プローブ[123I] IIMUの取り込み機構に関する検討2022
- Author(s)
  長谷川舞衣, 宿里充穗, 尾江悟, 水野雄貴, 久下裕司, 秋澤宏行
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K08105
[Presentation] レドックスイメージングを目的とした[64Cu][CuI(BCS)2]+の合成とROSとの反応性評価2022
- Author(s)
  多田哲朗、水野雄貴、柴田悠貴、安井博宣、久下裕司
- Organizer
  第5回日本核医学会分科会放射性薬品科学研究会
- Data Source
  KAKENHI-PROJECT-21K19433
[Presentation] Cystine-dense peptideを母体としたTfR1イメージング薬剤開発に向けた基礎的検討2022
- Author(s)
  林龍昕、水野雄貴、柴田悠貴、安井博宣、久下裕司
- Organizer
  第8回北大・部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-23K21417
[Presentation] 68Ga標識トランスフェリン受容体認識ペプチドによるがんイメージングの検討2021
- Author(s)
  三浦春香, 水野雄貴, 髙橋春香, 大久保直登, 前原経, 久下裕司, 武田宏司, 大西俊介
- Organizer
  第7回北大・部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-23K21417
[Presentation] ROSイメージングを目的としたメタボリックトラップ型PETプローブの開発：CuI-イソニトリル錯体の利用2021
- Author(s)
  多田哲朗, 水野雄貴, 柴田悠貴, 安井博宣, 久下裕司
- Organizer
  第7回北大・部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19433
[Presentation] 68Ga標識トランスフェリン受容体認識ペプチドによるがんイメージングの検討2021
- Author(s)
  三浦春香, 水野雄貴, 髙橋春香, 大久保直登, 前原経, 久下裕司, 武田宏司, 大西俊介
- Organizer
  第7回北大・部局横断シンポジウム
- Data Source
  KAKENHI-PROJECT-21K19433
[Presentation] マウス乳がんモデルにおけるエリブリンと放射線の併用療法に対する18F-DiFA PET低酸素イメージングを用いた効果判定予測に関する検討2021
- Author(s)
  安井博宣，房知輝，志賀哲，柴田悠貴，藤本政毅，鈴木基史，東川桂，宮本直樹，稲波修，久下裕司
- Organizer
  第58回生物部会学術大会・第49回放射線による制癌シンポジウム
- Data Source
  KAKENHI-PROJECT-19H04264
[Presentation] 18 F-DiFA PET/CTイメージングを用いたエリブリンによる腫瘍内低酸素解除効果の解析と放射線増感作用の検討2020
- Author(s)
  房知輝、安井博宣、志賀哲、柴田悠貴、藤本政毅、鈴木基史、東川桂、宮本直樹、稲波修、久下裕司
- Organizer
  日本放射線影響学会第63回大会
- Data Source
  KAKENHI-PROJECT-18H02757
[Presentation] A basic study on PET imaging technique for predicting cancer sensitivity to ferroptosis-targeting cancer therapy2019
- Author(s)
  Shibata Yuki、Higashikawa Kei、Yasui Hironobu、Kuge Yuji
- Organizer
  The 26th Annual Meeting of the Society for Free Radical Biology and Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04264
[Presentation] がんのフェロトーシス感受性評価のためのイメージング法開発に向けた基礎的検討2019
- Author(s)
  柴田悠貴、東川桂、安井博宣、久下裕司
- Organizer
  第14 回日本分子イメージング学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19H04264
[Presentation] 核医学診療に用いる放射性核種・放射性医薬品の基礎と今後の方向性2019
- Author(s)
  久下裕司
- Organizer
  第27回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-18H03548
[Presentation] 核医学治療に用いる放射性核種・放射性医薬品の基礎と今後の方向性2019
- Author(s)
  久下裕司
- Organizer
  第40回日本病院薬剤師会近畿学術大会
- Data Source
  KAKENHI-PROJECT-18H03548
[Presentation] 光免疫療法が腫瘍に及ぼす変化に関する[18F]FDGと[18F]FMISOを用いた検討2019
- Author(s)
  中島孝平、安井博宣、東川桂、高倉栄男、久下裕司、小川美香子
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03593
[Presentation] 光免疫療法による腫瘍環境の変化に関する[18F]FDG と[18F]FMISO を用いた検討2019
- Author(s)
  中島孝平、杉川晃代、安井博宣、東川桂、高倉栄男、志賀哲、久下裕司、小川美香子
- Organizer
  分子イメージング学会
- Data Source
  KAKENHI-PROJECT-19H03593
[Presentation] 含水18Ｆ溶液と濃縮18Ｆ化法による18-FMISOの18Ｆ化反応の検討2019
- Author(s)
  阿保憲史，桐生真登，東川桂，志賀哲，久下裕司
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K19640
[Presentation] 放射線治療を併用したフェロトーシス誘導がん治療法の検討2019
- Author(s)
  柴田悠貴、安井博宣、東川桂、宮本直樹、久下裕司
- Organizer
  第72回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-19H04264
[Presentation] Potentials of a thymidine phosphorylase imaging agent in the diagnosis of nonalcoholic steatohepatitis.2018
- Author(s)
  Higashikawa K, Horiguchi S, Uehara R, Tarisawa M, Shibata Y, Kitaura H, Yasui H, Takeda H, Kuge Y.
- Organizer
  The Tenth China-Japan-Korea Symposium on Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Presentation] チミジンホスホリラーゼイメージングプローブによる非アルコール性脂肪肝炎の診断法の開発研究。2018
- Author(s)
  東川桂、堀口紗和子、足澤誠、小松由紀子、大倉一枝、安井博宣、武田宏司、久下裕司。
- Organizer
  第13回日本分子イメージング学会
- Data Source
  KAKENHI-PROJECT-16K10335
[Presentation] Feasibility and potentials of thymidine phosphorylase (TP) as an imaging biomarker and its nuclear medicine imaging for the diagnosis of non-alcoholic　steatohepatitis.2018
- Author(s)
  Higashikawa K, Horiguchi S, Ebita Y, Tarisawa M, Komatsu Y, Ohkura K, Yasui H, Takeda H, Kuge Y.
- Organizer
  Society of Nuclear Medicine and Molecular Imaging 2018 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Presentation] Investigation of the influence of intratumoral glutathione status on the distribution of a hypoxic probe [18F]FMISO.2018
- Author(s)
  Yasui H, Higashikawa K, Shimizu Y, Shibata Y, Zhao S, Matsumoto H, Shiga T, Tamaki N, Kuge Y.
- Organizer
  WFNMB 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Presentation] チミジンホスホリラーゼ標的放射性プローブ[125I]IIMUの取り込みに対する有機カチオントランスポーターの影響2018
- Author(s)
  中山賢志、宿里充穂、東川桂、尾江悟、水野雄貴、大倉一枝、久下裕司、秋澤宏行
- Organizer
  日本薬学会第１３８年会（金沢）
- Data Source
  KAKENHI-PROJECT-26461802
[Presentation] マクロファージの極性化が18F-FMISOと125I-BMIPPの集積に及ぼす影響2017
- Author(s)
  1.本村新，志水陽一，高倉栄男，安井博宣，東川桂，玉木長良，久下裕司，小川美香子
- Organizer
  第1回放射性薬品科学研究会(京都市)
- Data Source
  KAKENHI-PROJECT-26293268
[Presentation] Effect of eribulin on remodeling of tumor vasculature confirmed by FMISO PET imaging-Small-animal PET study in human breast cancer cell xenograft-2017
- Author(s)
  Zhao S, Yu W, Ukon N, Nishijima K, Shimizu Y, Higashikawa K, Yamashita H, Tamaki N, Kuge Y.
- Organizer
  The 64th Society of Nuclear Medicine Annual Meeting in Denver
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Presentation] 小動物インビボイメージングの有用性2017
- Author(s)
  趙　松吉、久下　裕司、玉木　長良
- Organizer
  第26回日本バイオイメージング学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K10335
[Presentation] Accumulation mechanism of novel PET imaging probe “[18F]DiFA” in hypoxic cells revealed by imaging mass spectrometry.2017
- Author(s)
  Shimizu Y, Zhao S, Kishi R, Yasui H, Nishijima K, Matsumoto H, Tamaki N, Ogawa M, Kuge Y.
- Organizer
  The 64th Society of Nuclear Medicine Annual Meeting in Denver
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10335
[Presentation] Prognostic value of MET-PET in oral cancer2017
- Author(s)
  Chowdhury Nusrat Fatema, Kuroshima Takeshi, Asaka Takuya, Abe Takahiro, Sato Jun, Shiga Tohru, Kuge Yuji, Tamaki Nagara, Kitagawa, Yoshimasa
- Organizer
  The 64th Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05536
[Presentation] 18F-Fluoromisonidazole positron emission tomography (FMISO-PET) may better reflect hypoxia and cell proliferation activity in oral squamous cell carcinoma than 18F-fluoro-2-deoxyglucose (FDG)-PET: third study.2017
- Author(s)
  Sato Jun, Kitagawa Yoshimasa, Watanabe Shiro, Okamoto Shozo, Ohga, Noritaka, Asaka Takuya, Miyakoshi Masaaki, Hirata Kenji, Shiga Tohru, Kuge Yuji, Shindoh Masanobu, Tamaki Nagara
- Organizer
  The 64th Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05536
[Presentation] Metabolic Aspects of [14C]Acetete in Rabbit Atherosclerotic Arteries at Different Feeding Conditions: In Vitro Evaluation for Atherosclerosis Imaging with [11C]Acetate.2016
- Author(s)
  Yamasaki K, Yamashita A, Zhao Y, Shimizu Y, Kawai K, Tamaki N, Zhao S, Asada Y, Kuge Y.
- Organizer
  The Society of Nuclear Medicine 63th Annual Meeting
- Place of Presentation
  San Diego Convention Center, San Diego, California, U.S.A.
- Year and Date
  2016-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293260
[Presentation] Preclinical and translational researchs novel PET and SPECT tracers: 18F-Difa and 123I-IIMU for hypoxia and thymidine phosphorylase imaging2015
- Author(s)
  Zhao S., Nishijima K., Matsumoto H., Akizawa H., Ohkura K., Tamaki N., Kuge Y.
- Organizer
  アジアオセアニア核医学・生物学会（AOCNMB 2015）
- Place of Presentation
  韓国チェジュ
- Year and Date
  2015-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461802
[Presentation] 動脈硬化病変における放射性標識化免疫グロブリンG集積機序の探索2015
- Author(s)
  志水陽一、半澤宏子、趙芫、趙松吉、福良沙霧、西嶋剣一、坂本健、玉木長良、小川美香子、久下裕司
- Organizer
  第10回日本分子イメージング学会総会・学術総会、
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-26293268
[Presentation] Preclinical evaluation of thymidine phosphorylase imaging probe, [123I]IIMU, A road to First-in-human clinical study2015
- Author(s)
  Nishijima K, Zhao S, Matsumoto H, Akizawa H, Ohkura K, Shiga T, Hirata K, Watanabe S, Okamoto S, Tamaki N, Kuge Y
- Organizer
  Ninth Japan-China Joint Seminar on Radiopharmaceutical Chemistry
- Place of Presentation
  放射線医学総合研究所（千葉県・稲毛市）
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461782
[Presentation] Accumulation mechanism of non-targeted immunoglobulin G in atherosclerotic legions2015
- Author(s)
  Yoichi Shimizu, Hiroko Hanzawa, Yan Zhao, Songji Zhao, Sagiri Fukura, Ken-ichi Nishijima, Takeshi Sakamoto, Nagara Tamaki, and Yuji Kuge
- Organizer
  Annual Meeting of Society of Nuclear Medicine and Molecular Imaging
- Place of Presentation
  Baltimore Convention Center (Baltimore, Maryland)
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293268
[Presentation] Radiolabeled immunoglobulin G visualizes active inflammation in atherosclerosis2015
- Author(s)
  Sagiri Fukura, Yoichi Shimizu, Hiroko Hanzawa, Ken-ichi Nishijima, Takeshi Sakamoto, Songji Zhao, Mikako Ogawa, Yuji Kuge
- Organizer
  Ninth Japan-China Joint Seminar on Radiopharmaceutical Chemistry
- Place of Presentation
  National Institute of Radiological Sciences (Chiba, Japan)
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293268
[Presentation] Increased Metabolite Levels of Glycolysis and Pentose Phosphate Pathway in Rabbit Atherosclerotic Arteries and Hypoxic Macrophage.2014
- Author(s)
  Yamashita A., Zhao Y., Matsuura Y., Yamasaki K., Moriguchi-Goto S., Iwakiri T., Okuyama N., Koshimoto C., Kawai K., Tamaki N., Zhao S., Kuge Y., Asada Y.
- Organizer
  Arteriosclerosis, Thrombosis and Vascular Biology
- Place of Presentation
  Sheraton Centre Toronto Hotel, Toronto, Canada
- Year and Date
  2014-05-01
- Data Source
  KAKENHI-PROJECT-25293260
[Presentation] 肉芽腫・腫瘍の鑑別診断における18F-FMISO低酸素イメージング：小動物用PETを用いたラットモデルにおける14C-FDGとの比較2014
- Author(s)
  趙　松吉、久下　裕司、伊敏、趙　芫、西嶋　剣一、于　聞文、孫田　恵一、玉木　長良
- Organizer
  日本分子イメージング学会第９回総会・学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪市）
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] 抗血管新生剤(sorafenib)の抗腫瘍効果の機序：肺癌細胞移植モデルにおけるFMISOによる腫瘍内酸素状態の評価2013
- Author(s)
  于聞文、趙　松吉、村上　正紘、趙　芫、ファティマチョウドリヌスッラト、西嶋　剣一、北川　善政、玉木　長良、久下　裕司
- Organizer
  第５３回日本核医学学術総会
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] FMISO PET reflects antiangiogenic tumor response after sorafenib treatment in human renal cell carcinoma xenograft2013
- Author(s)
  Murakami M, Zhao S, Zhao Y, Chowdhury NF, Yu W, Nishijima K, Takiguchi M, Tamaki N, Kuge Y
- Organizer
  The 60^<th> Society of Nuclear Medicine and Molecular Imaging Annual Meeting
- Place of Presentation
  Vancouver
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] 抗血管新生剤(sorafenib)の抗腫瘍効果の機序:肺癌細胞移植モデルにおけるFMISOによる腫瘍内酸素状態の評価2013
- Author(s)
  于聞文、趙松吉、村上正紘、趙芫、ファティマチョウドリヌスッラト、西嶋剣一、北川善政、玉木長良、久下裕司
- Organizer
  第53回日本核医学学術総会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] FMISO PET reflects antiangiogenic tumor response after sorafenib treatment in human renal cell carcinoma xenograft2013
- Author(s)
  Murakami M, Zhao S, Zhao Y, Chowdhury NF, Yu W, Nishijima K, Takiguchi M, Tamaki N, Kuge Y
- Organizer
  The 60th Society of Nuclear Medicine and Molecular Imaging Annual Meeting
- Place of Presentation
  Vancouver Convention Center (Vancouver, Canada)
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] Preparation and evaluation of [123I]IIMU for SPECT imaging of thymidine phosphorylase expression in tumors.2013
- Author(s)
  Nishijima K, Zhao S, Zhao Y, Feng F, Shimizu Y, Abo N, Akizawa H, Ohkura K, Tamaki N, and Kuge Y
- Organizer
  20th International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] 腎細胞癌移植モデルにおける抗血管新生剤（sorafenib）の治療反応のFMISO PETによる評価2013
- Author(s)
  趙　松吉、于　聞文、村上　正紘、趙　芫、ファティマ　チョウドリ　ヌスラット、西嶋　剣一、右近　直之、久保　直樹、玉木　長良、久下　裕司
- Organizer
  第５３回日本核医学学術総会
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] Preparation and evaluation of IIMU for SPECT imaging thymidine phosphorylase expression in tumors2013
- Author(s)
  Nishijima K, Zhao S, Zhao Y, Feng F, Shimizu Y, Abo N, Akizawa H, Ohkura K, Tamaki N, Kuge Y
- Organizer
  20^<th> International Synposium on Radiopharmaceutical Sciences
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] チミジンホスホリラーゼイメージング剤[^<123>I]IIMUによるCapecitabineの治療効果予測2013
- Author(s)
  小橋信弥,女池俊介,奥村侑紀,阿部務,秋澤宏行,大倉一枝,西嶋剣一,趙松吉,久下裕司,松本博樹
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] 18F-FLT can predict tumor proliferation response to radiotherapy in human head and neck cancer xenograft in comparison with Ki-672013
- Author(s)
  Chowdhury NF, Zhao S, Zhao Y, Murakami M, Yu W, Nishijima K, Tamaki N, Kitagawa Y, Kuge Y
- Organizer
  日本薬学会第133回年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] Preparation and evaluation of [^<123>I]IIMU for SPECT imaging of thymidine phosphorylase expression in tumors2013
- Author(s)
  Nishijima K, Zhao S, Zhao Y, Feng F, Shimizu Y, Abo N, Akizawa H, Ohkura K, Tamaki N, Kuge Y
- Organizer
  The 20^<th> International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] Preparation and evaluation of [123I]IIMU for SPECT imaging of thymidine phosphorylase expression in tumors2013
- Author(s)
  Nishijima K, Zhao S, Zhao Y, Feng F, Shimizu Y, Abo N, Akizawa H, Ohkura K, Tamaki N, Kuge Y
- Organizer
  The 20th International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  Jeju International Convention Center (Jeju, Korea)
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] Sequential evaluation of intratumoral proliferative activity after radiotherapy by FLT in human head and neck cancer xenograft2013
- Author(s)
  Fatema CN, Zhao S, Zhao Y, Murakami M, Yu W, Nishijima K, Kitagawa Y, Tamaki N, Kuge Y
- Organizer
  The 60th Society of Nuclear Medicine and Molecular Imaging Annual Meeting
- Place of Presentation
  Vancouver Convention Center (Vancouver, Canada)
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] 腎細胞癌移植モデルにおける抗血管新生剤(sorafenib)の治療反応のFMISO PETによる評価2013
- Author(s)
  趙松吉、于聞文、村上正紘、趙芫、ファティマチョウドリヌスラット、西嶋剣一、右近直之、久保直樹、玉木長良、久下裕司
- Organizer
  第53回日本核医学学術総会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] FLT can early reflect response of tumor proliferation to multikinase inhibitor (sorafenib) treatment in a human renal cell carcinoma xenograft : comparison with Ki-672012
- Author(s)
  Murakami M, Zhao S, Zhao Y, Chowdhury NF, Yu W, Nishijima K, Takiguchi M, Tamaki N, Kuge Y
- Organizer
  The 2012 World Molecular Imaging Congress
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] 特別講演１．癌の診断・治療効果評価におけるPETの応用～基礎研究を中心に～　口腔顔面核医学フォーラム20122012
- Author(s)
  趙松吉、久下裕司、玉木長良
- Organizer
  第52回日本核医学会学術総会
- Place of Presentation
  ロイトン札幌（札幌市）
- Invited
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] チミジンホスホリラーゼを標的とする新規腫瘍イメージング剤（123I-IIMU）の開発：マウス組織におけるチミジンホスホリラーゼ発現と123I-IIMU集積との関係。2012
- Author(s)
  趙松吉、李花、西嶋剣一、秋澤宏行、大倉一枝、玉木長良、久下裕司
- Organizer
  第7回日本分子イメージング学会総会・学術集会
- Place of Presentation
  アクトシティ浜松（浜松市）
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] 固形腫瘍内における放射線誘導性再酸素化の動態の評価2012
- Author(s)
  永根大幹、安井博宣、趙松吉、久保直樹、玉木長良、久下裕司、稲波修
- Organizer
  第52回日本核医学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 特別講演１．癌の診断・治療効果評価におけるPETの応用～基礎研究を中心に～　口腔顔面核医学フォーラム20122012
- Author(s)
  趙松吉、久下裕司、玉木長良
- Organizer
  第52回日本核医学会学術総会
- Place of Presentation
  ロイトン札幌（札幌市）
- Invited
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] FLT can early reflect response of tumor proliferation to multikinase inhibitor (sorafenib) treatment in a human renal cell carcinoma xenograft: comparison with Ki-672012
- Author(s)
  Murakami M, Zhao S, Zhao Y, Nusrat C, Yu W, Nishijima K, Takiguchi M, Tamaki N, Kuge Y
- Organizer
  The 2012 World Molecular Imaging Congress
- Place of Presentation
  The Convention Centre Dublin - CCD( Ireland)
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Radiation-induced nitric oxide contributes to the tumor reoxygenation in SCCVII tumors2012
- Author(s)
  Nagane M, Yasui H, Yamamori T, Zhao S, Kuge Y, Kameya H, Nakamura H, and Inanami O N, Kuge Y
- Organizer
  The 59th Annual Meeting, Society of Nuclear Medicine
- Place of Presentation
  Miami, the Miami Beach Convention Center(US)
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 腫瘍・肉芽腫における18F-FMISO集積の特徴：18F-FDG及び組織学的比較2012
- Author(s)
  趙松吉、伊敏、趙芫、西嶋剣一、村上正紘、于聞文、チョウドリヌスラットファティマ、孫田恵、小華和柾志、玉木長良、久下裕司
- Organizer
  第52回日本核医学会学術総会
- Place of Presentation
  ロイトン札幌（札幌市）
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] FMISO PET reflects antiangiogenic tumor response to multi-kinase inhibitor (sorafenib) in human renal cell carcinoma xenograft2012
- Author(s)
  Murakami M, Zhao S, Zhao Y, Nusrat C, Yu W, Nishijima K, Takiguchi T, Tamaki N, Kuge Y
- Organizer
  The 59th Annual Meeting, Society of Nuclear Medicine
- Place of Presentation
  the Miami Beach Convention Center (Miami, US)
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] 腫瘍・肉芽腫における18F-FMISO集積の特徴：18F-FDG及び組織学的比較2012
- Author(s)
  趙松吉、伊敏、趙芫、西嶋剣一、村上正紘、于聞文、チョウドリヌスラットファティマ、孫田恵、小華和柾志、玉木長良、久下裕司
- Organizer
  第52回日本核医学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] チミジンホスホリラーゼイメージング剤[^<123>I]5-iodo-6-[(2-iminoimidazolidiny l)methyl]uracilの開発:タンパク結合測定と画像化の検討2012
- Author(s)
  西嶋剣一、越田早織、趙松吉、秋澤宏行、大倉一枝、松本博樹、志賀哲、玉木長良、久下裕司
- Organizer
  日本薬学会第132回年会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] FMISO PET reflects antiangiogenic tumor response to multi-kinase inhibitor (sorafenib) in human renal cell carcinoma xenograft2012
- Author(s)
  Murakami M, Zhao S, Zhao Y, Nusrat C, Yu W, Nishijima K, Takiguchi T, Tamaki N, Kuge Y
- Organizer
  The 59th Annual Meeting, Society of Nuclear Medicine
- Place of Presentation
  Miami, the Miami Beach Convention Center(US)
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] チミジンホスホリラーゼを標的とする新規腫瘍イメージング剤^<123>I-IIMUの開発:マウス組織におけるチミジンホスホリラーゼ発現と^<123/125>I-IIMU集積との関係2012
- Author(s)
  趙松吉,李花,西嶋剣一,秋澤宏行,大倉一枝,玉木長良,久下裕司
- Organizer
  第7回分子イメージング学会学術集会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] 18F-fluorodeoxyglucose uptake reflects thrombus formation and tissue factor expression via nuclear factor-kB in rabbit atherosclerotic lesions2012
- Author(s)
  Atsushi Yamashita, Yan Zhao, Yunosuke Matsuura, Kazuaki Yamasaki Chihiro Sugita, Keiichi Kawai, Nagara Tamaki, Songji Zhao, Yuji Kuge, Yujiro Asada
- Organizer
  American Heart Association Scientific Sessions 2012
- Place of Presentation
  Los Angeles Convention Center, Los Angeles, CA, U.S.A
- Data Source
  KAKENHI-PROJECT-23659573
[Presentation] 動脈血栓能を反映する18F-フルオロデオキシグルコースの血管集積2012
- Author(s)
  山下篤、趙芫、趙松吉、松浦祐之介、川井恵一、玉木長良、久下裕司、浅田祐士郎
- Organizer
  第52回日本核医学会学術総会。
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23659573
[Presentation] Reproducibility of hypoxic evaluation using FMISO-PET for head and neck cancer2012
- Author(s)
  Okamoto S, Shiga T, Yasuda K, Kasai K, Magota K, Kuge K, Shirato H, Tamaki
- Organizer
  The 59th Annual Meeting, Society of Nuclear Medicine
- Place of Presentation
  Miami, the Miami Beach Convention Center(US)
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] チミジンホスホリラーゼイメージング剤[^<123>I]5-iodo-6[(2-iminoimidazoli- dinyl)methyl]uracilの開発;タンパク結合測定と画像化の検討2012
- Author(s)
  西嶋剣一, 越田早織, 趙松吉, 秋澤宏行, 大倉一枝, 松本博樹, 志賀哲, 玉木長良, 久下裕司
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591826
[Presentation] チミジンホスホリラーゼを標的とする新規腫瘍イメージング剤(^<123>I-IIMU)の開発:マウス組織におけるチミジンホスホリラーゼ発現と^<123>I-IIMU集積との関係2012
- Author(s)
  趙松吉、李花、西嶋剣一、秋澤宏行、大倉一枝、玉木長良、久下裕司
- Organizer
  日本分子イメージング学会第7回総会・学術集会
- Place of Presentation
  浜松市
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] 腎細胞癌移植マウスにおけるマルチキナーゼ阻害剤Sorafenib治療後のFLTによる治療反応評価2012
- Author(s)
  村上正紘、趙松吉、趙芫、マチョウドリヌスラットファティ、于聞文、西嶋剣一、久保直樹、滝口満喜、玉木長良、久下裕司
- Organizer
  第52回日本核医学学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] FLT can early reflect response of tumor proliferation to multikinase inhibitor (sorafenib) treatment in a human renal cell carcinoma xenograft: comparison with Ki-672012
- Author(s)
  Murakami M, Zhao S, Zhao Y, Nusrat C, Yu W, Nishijima K, Takiguchi M, Tamaki N, Kuge Y
- Organizer
  The 2012 World Molecular Imaging Congress
- Place of Presentation
  The Convention Centre (Dublin, Ireland)
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] ^<18>F-FMISOを用いた腎細胞癌移植モデルにおける抗血管新生療法(sorafenib)の早期治療反応の評価2012
- Author(s)
  村上正紘、趙松吉、趙芫、チョウドリヌスラットファティマ、于聞文、西嶋剣一、滝口満喜、玉木長良、久下裕司
- Organizer
  日本分子イメージング学会第7回総会・学術集会
- Place of Presentation
  浜松市
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] The relationship between the pretreatment uptake area of FMISO and local recurrence site in nasopharyngeal cancer2012
- Author(s)
  Yasuda K, Tsuchiya K, Okamoto S, Onimaru R, Shiga T, Katoh N, Suzuki R, Harada K, Kuge Y, Tamaki N, Shirato H
- Organizer
  The 10th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  北海道医学部学友会館「フラテ」（札幌市）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] FMISO PET reflects antiangiogenic tumor response to multi-kinase inhibitor (sorafenib) in human renal cell carcinoma xenograft2012
- Author(s)
  Murakami M, Zhao S, Zhao Y, Chowdhury NF, Yu W, Nishijima K, Takiguchi M, Tamaki N, Kuge Y
- Organizer
  The 59^<th> Society of Nuclear Medicine Annual Meeting
- Place of Presentation
  Miami
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] チミジンホスホリラーゼイメージング剤[123I]5-iodo-6-[(2-iminoimidazolidinyl)methyl]uracilの開発：タンパク結合測定と画像化の検討2012
- Author(s)
  西嶋剣一、越田早織、趙松吉、秋澤宏行、大倉一枝、松本博樹、志賀　哲、玉木長良、久下裕司
- Organizer
  日本薬学会　第132年会
- Place of Presentation
  北海道大学（札幌）
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] FMISO PET can early evaluate antiangiogenic response to anti-EGFR molecular-targeting therapy (cetuximab) in human lung cancer xenograft2011
- Author(s)
  Zhao S, Kuge Y, Zhao Y, Takeuchi S, Murakami M, Li H, Nusrat F Chouwdhury, Nishijima K, Dosaka-Akita H, Tamaki N
- Organizer
  The 58th Annual Meeting, Society of Nuclear Medicine
- Place of Presentation
  The H.B.Gonzalez Convention Center (USA)
- Year and Date
  2011-06-06
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] ^<18>F-Fluorothymidine (18F-FLT) as early predictor of tumor response for anti-epidermal growth factor receptor antibody in human lung cancer xenograft2011
- Author(s)
  Takeuchi S, Zhao S, Kuge Y, Zhao Y, Nishijima K, Shimizu Y, Kinoshita I, Tamaki N, Dosaka-Akita H
- Organizer
  The 14^<th> World Conference on Lung Cancer
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] IGRTにPETを用いるための基礎研究。シンポジウム高精度放射線治療におけるPET/CTの役割2011
- Author(s)
  久下裕司
- Organizer
  第51回日本核医学会学術総会
- Place of Presentation
  つくば国際会議場(茨城)(招待講演)
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] ヒト癌移植マウスにおける抗EGFR抗体（Cetuximab）による分子標的療法：18F-FMISOを用いた早期治療効果評価。2011
- Author(s)
  趙　松吉、久下　裕司、趙　芫、竹内　啓、村上　正紘、李　花、チョウドリヌスラット　ファティマ、西嶋　剣一、竹井　俊樹、秋田　弘俊、玉木　長良。
- Organizer
  第5１回日本核医学会学術総会
- Place of Presentation
  つくば国際会議場（茨城）
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] ヒト癌移植マウスにおける抗EGFR抗体(Cetuximab)による分子標的療法:^<18>F-FMISOを用いた早期治療効果評価2011
- Author(s)
  趙松吉、久下裕司、趙芫、竹内啓、村上正紘、李花、チョウドリヌスラットファティマ、西嶋剣一、竹井俊樹、秋田弘俊、玉木長良
- Organizer
  第51回日本核医学会学術総会
- Place of Presentation
  つくば市
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] FMISO PET can early evaluate antiangiogenic response to anti-EGFR molecular-targeting therapy (cetuximab) in human lung cancer xenograft.2011
- Author(s)
  Zhao S, Kuge Y, Zhao Y, Takeuchi S, Murakami M, Li H, Nusrat F Chouwdhury, Nishijima K, Dosaka-Akita H, Tamaki N.
- Organizer
  The 58th Annual Meeting, Society of Nuclear Medicine
- Place of Presentation
  The H.B. Gonzalez Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] ^<18>F-FMISO accumulates in gliobalstoma multiforme but not in grade III or less malignant gliomas2011
- Author(s)
  Hirata K, Hattori N, Shiga T, Usui R, Yamaguchi S, Terasaka S, Narita T, Tanaka S, Kuge Y, Tamaki N
- Organizer
  The 58th Annual Meeting, Society of Nuclear Medicine
- Place of Presentation
  The H.B.Gonzalez Convention Center (USA)
- Year and Date
  2011-06-06
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] IGRTにPETを用いるための基礎研究。シンポジウム高精度放射線治療におけるPET/CTの役割2011
- Author(s)
  久下裕司
- Organizer
  第51回日本核医学会学術総会
- Place of Presentation
  つくば国際会議場(つくば)
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 18F-Fluorothymidine PET/CT as early predictor of tumor response for anti-epidermal growth factor receptor antibody in human lung cancer xenograft.2011
- Author(s)
  Takeuchi S, Zhao S, Kuge Y, Zhao Y, Nishijima K, Shimizu Y, Kinoshita I, Tamaki N and Dosaka-Akita H.
- Organizer
  The AACR 102nd Annual Meeting
- Place of Presentation
  The Orange County Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] FMISO PET can early evaluate antiangiogenic response to anti-EGFR molecular-targeting therapy (cetuximab) in human lung cancer xenograft2011
- Author(s)
  Zhao S, Kuge Y, Zhao Y, Takeuchi S, Murakami M, Li H, Nusrat C, Nishijima K, Dosaka-Akita H, Tamaki N
- Organizer
  The 58^<th> Society of Nuclear Medicine Annual Meeting
- Place of Presentation
  San Antonio
- Data Source
  KAKENHI-PROJECT-23591742
[Presentation] Careful assessment of FDG uptake due to elevated FDG concentration in the blood and organs by high dose ARB administration: Experiment in mice given telmisartan2010
- Author(s)
  Zhao Y, Zhao S, Kuge Y, Tamaki N
- Organizer
  56 th Annual Meeting, Society of Nuclear Medicine
- Place of Presentation
  Salt Lake City
- Data Source
  KAKENHI-PROJECT-20390321
[Presentation] [^<11>C] phosgeneを用いるoxoimidazolidinylmethyluracilの合成とがんイメージングプローブへの応用2010
- Author(s)
  関興一・西嶋剣一・高橋正幸・趙松吉・向田理恵・秋澤宏行・久下裕司・玉木長良・大倉一枝
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  大阪(近畿大学)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20591457
[Presentation] 頭部外傷患者におけるIMZ SPECTとFMZ PETとの比較2010
- Author(s)
  志賀哲、生駒一憲、臼居礼子、平田健司、服部直哉、加藤千恵次、久下祐司、玉木長良
- Organizer
  第50回日本核医学会総会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-20591429
[Presentation] 頭部外傷患者におけるIMZ SPECTとFMZ PETとの比較2010
- Author(s)
  志賀哲、生駒一憲、臼居礼子、平田健司、服部直哉、加藤千恵次、久下祐司、玉木長良
- Organizer
  第122回日本医学放射線学会北日本地方会
- Place of Presentation
  仙台
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-20591429
[Presentation] A novel radiolabeled probe for molecular imaging of thymidine phosphorylase : Suppressed accumulation into tumor cells by target gene knockdown.2010
- Author(s)
  Li H, Zhao S, Jin Y, Nishijima K, Akizawa H, Ohkura K, Seki K, Tamaki N, Kuge Y
- Organizer
  2010 World Molecular Imaging Congress
- Place of Presentation
  Kyoto, Japan.
- Data Source
  KAKENHI-PROJECT-20390320
[Presentation] I-123 IMZ SPECT may detect loss of neuronal integrity in patients with traumatic brain injury.2010
- Author(s)
  Tohru Shiga, Katsunori Ikoma, Reiko Usuil, Kenji Hirata, Naoya Hattori, Yuji Kuge, Satoshi Terae, Nagara Tamaki
- Organizer
  The 57th Annual Meeting, Society of nuclear medicine.
- Place of Presentation
  Salt lake city
- Data Source
  KAKENHI-PROJECT-20591429
[Presentation] [11C]phosgene を用いるoxo-imidazolidinylmethyluracil の合成とがんイメージングプローブへの応用2010
- Author(s)
  関興一・西嶋剣一・高橋正幸・趙松吉・向田理恵・秋澤宏行・久下裕司・玉木長良・大倉一枝
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20591457
[Presentation] Hyoxia imaging with ^<18>F-fluoromisonidazole (FMISO) for differentiating tumors from granulomas : A comparison with FDG in experimental rat models using small animal PET.2010
- Author(s)
  Zhao S, Kuge Y, Zhao Y, Yi M, Hatano T, Suzuki K, Magota K, Nishijima K, Kohanawa M, Tamaki N
- Organizer
  57th Annual Meeting of the Society of Nuclear Medicine
- Place of Presentation
  Salt Lake City.
- Data Source
  KAKENHI-PROJECT-20390320
[Presentation] 動物用PETを用いた分子イメージング研究-「腫瘍の診断と治療効果評価-2010
- Author(s)
  久下裕司, 他
- Organizer
  日本放射線安全管理学会第9回学術大会
- Place of Presentation
  東広島(広島大学) 招待講演
- Data Source
  KAKENHI-PROJECT-20390320
[Presentation] Biologic aspects of intratumoral [^<18>F]FMISO distribution in a rodent model of glioma.2010
- Author(s)
  Hatano T, Zhao S, Zhao Y, Nishijima K, Kuno K, Hanzawa H, Sakamoto T, Tamaki N, Kuge Y
- Organizer
  57th Annual Meeting of the Society of Nuclear Medicine
- Place of Presentation
  Salt Lake City.
- Data Source
  KAKENHI-PROJECT-20390320
[Presentation] FLT PET can early predict antiproliferative response to anti-EGFR moleculartargeting therapy (cetuximab) in human lung cancer xenograft.2010
- Author(s)
  Zhao S, Takeuchi S, Kuge Y, Zhao Y, Hatano T, Li H, Nishijima K, Kinoshita I, Dosaka-Akita H, Tamaki N
- Organizer
  57th Annual Meeting of the Society of Nuclear Medicine
- Place of Presentation
  Salt Lake City.
- Data Source
  KAKENHI-PROJECT-20390320
[Presentation] 分子イメージング装置を用いた研究とその成果～動物用PETを中心に～2010
- Author(s)
  久下裕司, 他
- Organizer
  日本動物技術者協会第44回全国総会
- Place of Presentation
  旭川(旭川市民会館) 招待講演
- Data Source
  KAKENHI-PROJECT-20390320
[Presentation] A radioiodinated lumiracoxib derivative: synthesis and in vitro/in vivo evaluation as a SPECT tracer for cyclooxygenase-2 expression2009
- Author(s)
  Kuge Y, Obokata N, Kimura H, Saji H, et al.
- Organizer
  International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  Edmonton
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] A radioiodinated lumiracoxib derivative : synthesis and in vitro/in vivo evaluation as a SPECT tracer for cyclooxygenase-2 expression2009
- Author(s)
  Kuge Y, et al.
- Organizer
  18th International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  Edmonton, Canada
- Data Source
  KAKENHI-PROJECT-20390320
[Presentation] A radioiodinated lumiracoxib derivative : synthesis and in vitro/in vivo evaluation as a SPECT tracer for cyclooxygenase-2 expression2009
- Author(s)
  Kuge Y, Obokata N, Kimura H, et al.
- Organizer
  18th International Symposium on Radiopharmaceutical Sciences
- Place of Presentation
  Shaw Convention Centre(Edmonton, Canada)
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] Prediction of early antiproliferative response to anti-VEGF monoclonal antibody molecular-targeting therapy (bevacizumab) in human tumor xenograft using FLT.2009
- Author(s)
  Zhao S, Kuge Y, Zhao Y, Takeuchi S, Jin Y, Hatano T, Kinoshita I, Dosaka-Akita H, Tamaki N
- Organizer
  56th Annual Meeting of the Society of Nuclear Medicine
- Place of Presentation
  Tronto.
- Data Source
  KAKENHI-PROJECT-20390320
[Presentation] A Novel Non-peptidergic Tracer for PET Imaging of BACEl Density in Alzheimer's Disease Brain2008
- Author(s)
  Kawashima H, Kawai T, Kuge Y, Saji H
- Organizer
  2008 World Molecular Imaging Congress
- Place of Presentation
  Nice (France)
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] Brain derived neurotrophic factor (BDNF) の発現低下は脳虚血後の環境刺激による神経機能回復に関係する2008
- Author(s)
  生野雄二, 横田千晶, 久下裕司, 井上裕康, 小亀浩一, 木戸慎介, 原田晃名, 堀田真理子, 佐治英郎, 峰松一夫
- Organizer
  第20回日本脳循環代謝学会総会
- Place of Presentation
  東京ドームホテル東京都
- Data Source
  KAKENHI-PROJECT-18591619
[Presentation] Synthesis of a Potential SPECT Tracer for Angiogenic Enzyme Expression Graduate School of Medicine.2008
- Author(s)
  Seki K, Takahashi M, Zhao S, Nishijima K, Kuge Y, Tamaki N, Ohkura K
- Organizer
  2008 World Molecular Imaging Congress
- Place of Presentation
  Nice.
- Data Source
  KAKENHI-PROJECT-20390320
[Presentation] A Novel Non-peptidergic Tracer for PET Imaging of BACE1 Density in Alzheimer's Disease Brain2008
- Author(s)
  Kawashima H, Kawai T, Kuge Y, Saji H, et al.
- Organizer
  World Molecular Imaging Congress
- Place of Presentation
  Nice
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] アルツハイマー病における脳内β-セクレクーゼイメージングを目的としたhydroxyethylamine dipeptide isoster誘導体の標識合成2008
- Author(s)
  河合知喜, 河嶋秀和, 木村寛之, 久下裕司, 佐治英郎
- Organizer
  日本分子イメージング学会第4回学術総会
- Place of Presentation
  埼玉
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] Brainderived neurotrophic factor (BDNF)の発現低下は脳虚血後の環境刺激による神経機能回復に関係する2008
- Author(s)
  生野雄二、横田千晶、久下裕司、井上裕康、小亀浩一、木戸慎介、原田晃名、堀田真理子、佐治英郎、峰松一夫
- Organizer
  第20 回日本脳循環代謝学会総会
- Place of Presentation
  第20 回日本脳循環代謝学会総会東京ドームホテル東京都
- Data Source
  KAKENHI-PROJECT-18591619
[Presentation] Decrease in brain derived neurotrophic factor expression is associated with functional recovery in an enriched environment after experimental stroke2008
- Author(s)
  Shono Y, Kuge Y, Yokota C, Harada A, Kido S, Kokame K, Inoue H, Hotta M, Saji H, Minematsu K
- Organizer
  International Stroke Conference 2008
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-18591619
[Presentation] 細胞の増殖脳の評価及び腫瘍と肉芽腫の鑑別診断における11C-メチオニンの有用性:18F-FDGとの比較2007
- Author(s)
  趙松吉, 久下裕司, 小華和柾志, 趙芫, 鐘ケ江香久子, 関興一, 玉木長良
- Organizer
  第2回日本分子イメージング学会総合・学術集会
- Place of Presentation
  福井福井フェニックスプラザ
- Data Source
  KAKENHI-PROJECT-18209039
[Presentation] Analysis of gene expression related to enrich environment after transient focal brain ischemia in rats2007
- Author(s)
  Shono Y, Kuge Y, Yokota C, Kido S, Kokame K, Inoue H, Hotta M, Minematsu K, Saji H
- Organizer
  Brain'07 & BrainPET '07
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-18591619
[Presentation] Membrane type-1 matrix metalloproteinase (MT1-MMP), a potential target for radioimmuno-detection and therapy of malignant tumors: Evaluation in experimental rat models.2007
- Author(s)
  Kuge Y , et. al.
- Organizer
  Joint Molecular Imaging Conference
- Place of Presentation
  Providence, Rhode Island Convention Center
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390332
[Presentation] Evaluation of the effects of hypertension on cerebral metabolic functions after the onset of stroke in spontaneously hypertensive rats (SHR)2007
- Author(s)
  Temma T, Kuge Y, Sano K, Obokata N, Kamihashi J, Kawashima H, Magata Y, Saji H
- Organizer
  54th Annual Meeting of the Society of Nuclear Medicine
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-18591619
[Presentation] 放射線治療後の脳腫瘍再発と放射線性壊死の鑑別におけるmethionine PETの有用性2007
- Author(s)
  岡本祥三, 志賀哲, 鐘ケ江香久子, 吉永恵一郎, 犬伏正幸, 井上哲也, 平田健司, 真鍋治, 久下裕司, 玉木長良
- Organizer
  第47回日本核医学会学術総会
- Place of Presentation
  仙台,仙台国際センター
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-18209039
[Presentation] Analysis of gene expression related to enrich environment after transient focal brain ischemia in rats.2007
- Author(s)
  Shono Y, Kuge Y, Yokota C, Kido S, Kokame K, Inoue H, Hotta M, Minematsu K, Saji H
- Organizer
  Brain '07 & BrainPET '07
- Place of Presentation
  Osaka, Japan
- Data Source
  KAKENHI-PROJECT-18591619
[Presentation] Membrane type-1 matrix metalloproteinase(MT1-MMP), a potential tanget for radioimmuno-detection and therapy of malignant tumors: Evaluation in experimental rat models.2007
- Author(s)
  Kuge Y , et. al.
- Organizer
  Joint Molecular Imaging Conference
- Place of Presentation
  Providence・Rhode Island Convention Center
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390332
[Presentation] Usefulness of 11C-methionine in evaluating cellular proliferation and differential diagnosis of tumor and granuloma: An experimental study in comparison with 18F-FDG2007
- Author(s)
  Zhao S, Kuge Y, Kohanawa M, Zhao Y, Kanegae K, Seki K, Tamaki N
- Organizer
  The 54th Annual Meeting, Society of Nuclear Medicine
- Place of Presentation
  Washington DCワシントン条約センター
- Year and Date
  2007-06-03
- Data Source
  KAKENHI-PROJECT-18209039
[Presentation] Evaluation of the effects of hypertension on cerebral metabolic functions after the onset of stroke in spontaneously hypertensive rats(SHR)2007
- Author(s)
  Temma T, Kuge Y, Sano K, Obokata N, Kamihashi J, Kawashima H, Magata Y, Saji H
- Organizer
  54th Annual Meeting of the Society of Nuclear Medicine
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-18591619
[Presentation] 細胞増殖能評価、腫瘍-肉芽腫の鑑別診断における11C-methionineと18F-FDGの比較2007
- Author(s)
  趙松吉, 久下裕司, 趙芫, 竹井俊樹, 加藤誠一, 鐘ケ江香久子, 岡本祥三, 加藤千恵次, 関興一, 玉木長良
- Organizer
  第47回日本核医学会学術総会
- Place of Presentation
  仙台,仙台国際センター
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-18209039
[Presentation] Membrane type-1 matrix metalloproteinase(MT1-MMP), a potential target for radioimmuno-detection and therapy of malignant tumors: Evaluation in experimental rat models. Joint Molecular Imaging Conference, September, 2007, providence.2007
- Author(s)
  Kuge Y, et. al.
- Organizer
  Joint Molecular Imaging Conference
- Place of Presentation
  Providence・Rhode Island Convention Center
- Data Source
  KAKENHI-PROJECT-17390332
[Presentation] Complementary role of methionine-PET and FDG-PET for differentiation between benign lesions lung cancer in patients with pneumoconiosis.2007
- Author(s)
  Kanegae K, Nakano I, Kimura K, Kaji H, Kuge Y, Shiga T, Zhao S, Okamoto S, Tamaki N
- Organizer
  The 54th Annual Meeting, Society of Nuclear Medicine
- Place of Presentation
  Washington DCワシントン条約センター
- Year and Date
  2007-06-04
- Data Source
  KAKENHI-PROJECT-18209039
[Presentation] Membrane type-1 matrix metalloproteinase (MT1-MMP), a potential target for radioimmuno-detection and therapy of malignant tumors: Evaluation in experimental rat models.2007
- Author(s)
  Kuge Y, et. al.
- Organizer
  Joint Molecular Imaging Conference
- Place of Presentation
  Providence, Rhode Island Convention Center
- Data Source
  KAKENHI-PROJECT-18209039
[Presentation] 3H-FLTによる癌の分子標的療法の早期評価:胆がんマウスにおける投与量依存性の検討2007
- Author(s)
  趙松吉, 久下裕司, 趙芫, 竹井俊樹, 鐘ケ江香久子, 犬伏正幸, 志賀哲, 加藤千恵次, 関興一, 玉木長良
- Organizer
  第47回日本核医学会学術総会
- Place of Presentation
  仙台,仙台国際センター
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-18209039
[Presentation] 塵肺合併肺癌の検出におけるFDG-PET後期像追加の意義の検討2007
- Author(s)
  鐘ケ江香久子, 志賀哲, 中野郁夫, 木村清延, 加地浩, 岡本祥三, 真鍋治, 趙松吉, 久下裕司, 玉木長良
- Organizer
  第47回日本核医学会学術総会
- Place of Presentation
  仙台,仙台国際センター
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-18209039
[Presentation] 18F-FLT but not 18F-FDG can early and dose-dependently detect antiproliferative responses of human tumor xenograft to epidermal growth factor receptor targeting with a tyrosine kinase inhibitor, gefitinib2007
- Author(s)
  Zhao S, Kuge Y, Zhao Y, Takei T, Kanegae K, Inubushi M, Shiga T, Seki K, Tamaki N
- Organizer
  The 54th Annual Meeting, Society of Nuclear Medicine
- Place of Presentation
  Washington DCワシントン条約センター
- Year and Date
  2007-06-04
- Data Source
  KAKENHI-PROJECT-18209039
[Presentation] 多目的自動合成装置を用いたクリック反応による18F-標識ペプチドの合成：5-[18F]fluoro-1-pentyneの合成検討
- Author(s)
  大曲茂生, 小松由紀子,西嶋剣一, 志水陽一, 馮飛, 玉木長良, 久下裕司
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県・神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26293268
[Presentation] Preclinical evaluation of thymidine phosphorylase imaging probe, 123I-IIMU for the First-in-Human clinical trials.
- Author(s)
  Nishijima K, Zhao S, Feng F, Shimizu Y, Akizawa H, Ohkura K, Kobashi N. Abe T, Matsumoto H, Tamaki N, Kuge Y
- Organizer
  The 12th International Symposium for Future Drug Discovery and Medical Care, Perspectives of Molecular and Target Therapy
- Place of Presentation
  Sapporo
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-26461802

1. TAMAKI Nagara (30171888)

# of Collaborated Projects: 21 results

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Kuge Yuji 久下 裕司

KUGE Yuji 久下 裕司

KUGA Yuji 久下 祐司

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Prediction and assessment of ferroptosis-inducing cancer therapy using a novel PET probe targeting Tf-receptorPrincipal Investigator

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Ferroptosis imaging with PET: Challenge to assess vulnerability of atherosclerotic plaquesPrincipal Investigator

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PET imaging for cancer treatment inducing ferrotosisPrincipal Investigator

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Kuge Yuji 久下裕司

KUGE Yuji 久下裕司

KUGA Yuji 久下祐司