Kawashima Hidekazu 河嶋秀和

… Alternative Names

Researcher Number	70359438
Other IDs
Affiliation (Current)	2021: 京都薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2021: 京都薬科大学, 薬学部, 准教授 2015 – 2019: 京都薬科大学, 薬学部, 准教授 2017: 独立行政法人国立循環器病研究センター, 研究所, 室長 2015: 京都薬科大学, 放射性同位元素研究センター, 准教授 2014: 北海道医療大学, 薬学部, 准教授 … More
Review Section/Research Field	Principal Investigator Radiation science / Physical pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related Except Principal Investigator Radiation science / Radiation science / Physical pharmacy / Basic / Social brain science / Applied pharmacology / General internal medicine and related fields / Medical systems / Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator 放射線 / 分子イメージング / 腫瘍 / 転移性腫瘍 / 組織トラップ型薬剤 / 可視化 / 悪性度診断 / 代謝トラッピング / インビボ画像診断法 / アルツハイマー病 … More Except Principal Investigator 放射線 / 分子イメージング / PET / SPECT / 腫瘍 / 画像診断 / 核医学 / 脳腫瘍 / 悪性度診断 / ポジトロン断層法 / brain tumor / positron emission tomography / 5IA / インビボイメージング / 炎症 / 鑑別診断 / 核酸合成 / プロスタグランジン / チミジン / シクロオキシゲナーゼ / 低酸素領域 / 低酸素誘導因子 / ビオチン誘導体 / 放射性医薬品 / マイクロ・ナノデバイス / 医療・福祉 / 薬学 / 有機化学 / アルツハイマー病 / 放射線画像診断 / トランスレーショナルリサーチ / 痴呆 / 脳神経疾患 / リハビリテーション / マイクロアレイ / 移植・再生医療 / 膵島β細胞 / 糖尿病 / 早期診断 / フルオロデオキシグルコース / 乳癌 / 早期発見 / 高感度 / 高分解能 / FDG / 核医学診断 / チミジンホスホリラーゼ / 治療効果判定 / フッ素標識チミジン誘導体 / evaluation of malignant potential / evaluation of treatment effect / fluorinated thymidine derivative / 頭頚部悪性腫瘍 / 放射線治療 / 非侵襲性 / F18-フルオロチミジン / F18-FDG / 頭頚部腫瘍 / 非浸襲性 / Head and neck tumor / radiation therapy / Non-invasiveness / 18F-FLT / 18F-FDG / 脳内神経変性疾患 / 再生医療 / 効果判定 / パーキンソン病モデルラット / 胎仔脳移植 / ドーパミン神経機能 / ドーパ脱炭酸酵素 / 早期画像診断 / 神経変性疾患 / 早期検出 / 再生医療効果判定 / 放射性診断薬 / 神経化学的評価 / Neurodegeneration / Intrastriatal grafts / Early detection / Parkinsonism model rat / Dopaminergic neuron / Amino acid transport / Dopa decarboxylase / Imaging diagnosis / ニコチン / 喫煙 / 受容体 / ニコチン受容体 / nAChR / 定量 / 禁煙 / nicotine / smoking / neuroreceptor / チミジン誘導体 / thymidine derivative / malignant grade evaluation / 小動物 / 標準酸素 / 非侵襲 / 定量化 / 脳虚血 / 脳血流量 / 酸素代謝量 / 標識酸素 / 脳酸素代謝量 / がんTheranostics / フレキシブルTheranosticsプローブ / EGFR / EphA2 / PET/SPECTイメージング / EGFRvIII / Fzd3 / トランスポゾンシステムを用いたマウスモデル / がんの早期発見 / 画像診断法・治療法 / 医用画像 / 画像再構成アルゴリズム / 分子機能 / 高解像度 / ピンホールコリメータ / 医療 / 生体機能 / 画像 / アルゴリズム / 多発性骨髄腫 / エクソソーム / CD63 / 核酸医薬 / 抗体薬物複合体 Less

スカベンジャー受容体のイメージングに基づく生活習慣病および悪性腫瘍の評価Principal InvestigatorOngoing
- Principal Investigator
  
  河嶋秀和
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kyoto Pharmaceutical University
Development of exosome-capturing antibody-conjugated nucleic acid medicines against multiple myelomaOngoing
- Principal Investigator
  
  芦原英司
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Pharmaceutical University
Development and application of novel chemical compounds to materialize the cancer theranostics
- Principal Investigator
  
  Yasui Hiroyuki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  General internal medicine and related fields
- Research Institution
  Kyoto Pharmaceutical University
Development of 125I-labeled probe for the detection of macrophage-like cells in inflammatory lesionPrincipal Investigator
- Principal Investigator
  
  Kawashima Hidekazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto Pharmaceutical University
Usefulness of imaging tumor-specific enzyme expression by radiopharmaceuticals with thymidine phosphorylase inhibitory potency
- Principal Investigator
  
  Ohkua Kazue
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Health Sciences University of Hokkaido
Development of an image reconstruction algorithm for image improvement of ultra-high spatial resolution SPECT for molecular functional quantitation in a selected small region
- Principal Investigator
  
  ZENIYA Tsutomu
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  Hirosaki University
  National Cardiovascular Center Research Institute
Development of noninvasive PET system with 15O labeled gas tracers in small animals for understanding cerebral ischemic disease
- Principal Investigator
  
  Moriguchi Tetsuaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Basic / Social brain science
  Applied pharmacology
- Research Institution
  University of Tsukuba
  National Cardiovascular Center Research Institute
Development of molecular imaging probes for measurement of mass in pancreatic islets.
- Principal Investigator
  
  SAJI Hideo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Diagnostic imaging of breast cancer using newly-developed dedicated PET scanners.
- Principal Investigator
  
  NAKAMOTO Yuji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
Synthesis and evaluation of an in vivo imaging probe for tumor based on the intracellular transporting systemPrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Hidekazu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  National Cardiovascular Center Research Institute
Development of probes for the systematic analysis of Alzheimer's disease : establishment of a new diagnostic imaging.
- Principal Investigator
  
  SAJI Hideo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
脳機能再生機構の解析と分子イメージング~臨床画像診断の実現を目指して~
- Principal Investigator
  
  久下裕司
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Development of a brain β-secretase imaging probe for the very early detection of Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Hidekazu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
マイクロリアクタによるポジトロンプローブの合成:チップ型自動合成装置の開発へ
- Principal Investigator
  
  久下裕司
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
酸素応答分解型タンパクを用いる低酸素領域のインビボ放射性イメージング法の開発
- Principal Investigator
  
  佐治英郎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
腫瘍の悪性度・転位能の評価を目的とした新規組織トラップ型核医学診断薬剤の開発Principal Investigator
- Principal Investigator
  
  河嶋秀和
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
DEVELOPMENT OF NOVEL RADIOPHARMACEUTICALS FOR EARLY STAGE DIAGNOSIS OF CEREBRAL NEURODEGENERATION AND FUNCTIONAL RECOVERRY AFTER INTRASTRIATAL GRAFTS
- Principal Investigator
  
  KAWAI Keiichi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kanazawa University
Quantitative Analysis of Nicotinic Acetylcholine Receptors in Human Brain ; Effects of Aging and Smoking Cessation
- Principal Investigator
  
  ISHIZU Koichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University
ESTABLISHMENT AND CLINICAL APPLICATION OF PROLIFERATION ACTIVITY AND MALIGNANT GRADE EVALUATION WITH POSITRON EMISSION TOMOGRAPHY.
- Principal Investigator
  
  SAGA TSUNEO
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES
  Kyoto University
EVALUATION OF THERAPEUTIC EFFECT BY POSITRON EMISSION TOMOGRAPHY USING FLUORINATED THYMIDINE DELIVATIVE
- Principal Investigator
  
  SAGA Tsuneo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
Monitoring radiation therapy to the head and neck tumor by FLT-PET.
- Principal Investigator
  
  SAKAMOTO Setsu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Foundation of biomedical research and innovation
核酸合成・PG合成酵素のインビボイメージング:腫瘍・炎症の鑑別診断への挑戦
- Principal Investigator
  
  KUGE Yuji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kyoto University

All 2018 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Patent

[Journal Article] 123I-labeled oxLDL is widely distributed throughout the whole body in mice2018
- Author(s)
  Nakano Atushi、Kawashima Hidekazu、Miyake Yoshinori、Zeniya Tsutomu、Yamamoto Akihide、Koshino Kazuhiro、Temma Takashi、Fukuda Tetsuya、Fujita Yoshiko、Kakino Akemi、Kanaya Shigehiko、Sawamura Tatsuya、Iida Hidehiro
- Journal Title
  
  Nuclear Medicine and Molecular Imaging
  
  Volume: 52 Pages: 144-153
- DOI
  10.1007/s13139-017-0497-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01309, KAKENHI-PROJECT-17K19670, KAKENHI-PROJECT-26350558
[Journal Article] Evaluation of 18F-labeled exendin(9-39) derivatives targeting glucagon-like peptide-1 receptor for pancreatic β-cell imaging2018
- Author(s)
  Kimura H, Ogawa Y, Fujimoto H, Mukai E, Kawashima H, Arimitsu K, Toyoda K, Fujita N, Yagi Y, Hamamatsu K, Murakami T, Murakami A, Ono M, Nakamoto Y, Togashi K, Inagaki N, Saji H.
- Journal Title
  
  Diabetes Res Clin Pract
  
  Volume: 26 Pages: 143-149
- DOI
  10.1016/j.bmc.2017.12.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08488, KAKENHI-PROJECT-16H05326, KAKENHI-PROJECT-17K19670
[Journal Article] Microwave-Assisted Synthesis of Organometallic Complexes of 99mTc(CO)3 and Re(CO)3: Its Application to Radiopharmaceuticals2012
- Author(s)
  Hiroyuki Kimura, Daisuke Mori, Naoya Harada, Masahiro Ono, Yoshiro Ohmomo, Tetsuya Kajimoto, Hidekazu Kawashima, Hideo Saji
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 60(1) Issue: 1 Pages: 79-85
- DOI
  10.1248/cpb.60.79
- NAID
  130001852351
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249046, KAKENHI-PROJECT-23791413
[Journal Article] Microwave-assisted Synthesis of Organometallic Complexes of ^99mTc(CO)_3 and Re(CO)_3: Its Application to Radiopharmaceuticals.2012
- Author(s)
  Hiroyuki Kimura, Daisuke Mori, Naoya harada, .Masahiro Ono, Yoshiro Ohmomo, Tetsuya Kajimoto, Hidekazu Kawashima, Hideo Saji
- Journal Title
  
  Chemical & Pharmaceutical Bulletin
  
  Volume: 60(1) Pages: 79-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249046
[Journal Article] Fluoro-pegylated chalcones as positron emission tomography probes for in vivo imaging of β-amyloid plaques in Alzheimer's disease2009
- Author(s)
  Ono M, Watanabe R, Kawashima H, et al.
- Journal Title
  
  Journal of Medicinal Chemistry 52
  
  Pages: 6394-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] ^<18>F-labeled flavones for in vivo imaging of beta-amyloid plaques in Alzheimer's brains2009
- Author(s)
  Ono M, Watanabe R, Kawashima H, et al
- Journal Title
  
  Bioorganic Medicinal Chemistry 17
  
  Pages: 2069-2076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209041
[Journal Article] 5-Iodo-A-85380, a specific ligand for α_4β_2 nicotinic acetylcholine receptors, prevents glutamate neurotoxicitv in rat cortical cultured neurons.2008
- Author(s)
  Ueda M., Iida Y., Kitamura Y., Kawashima H., Ogawa M., Maeata Y, Saji H.
- Journal Title
  
  Brain Res. 1199
  
  Pages: 46-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] 5-Iodo-A-85380, a specific ligand for α_4β_2 nicotinic acetylcholine receptors, prevents glutamate neurotoxicity in rat cortical cultured neurons.2008
- Author(s)
  Ueda M., Kawashima H., Magata Y., et al.
- Journal Title
  
  Brain Res. 1199
  
  Pages: 46-52
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] PET O-15 cerebral blood flow and metabolism after acute stroke in spontaneously hypertensive rats.2008
- Author(s)
  Temma T,. Kuge Y, Sano K., Kamihashi J., Obokata N., Kawashima H,. Magata Y., Saji H.
- Journal Title
  
  Brain Res. 1212
  
  Pages: 18-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] PET O-15 cerebral blood flow and metabolism after acute stroke in spontaneously hypertensive rats.2008
- Author(s)
  Temma T., Kawashima H., Magata Y., et al.
- Journal Title
  
  Brain Res. 1212
  
  Pages: 18-24
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] Extensive FDG uptake and its modification with corticosteroid in a granuloma rat model : An experimental study for differentiating granuloma from tumors.2007
- Author(s)
  Zhao S., Kawashima H., Temma T., et al.
- Journal Title
  
  Eur. J. Nucl. Med. Mol. Imaging 34
  
  Pages: 2096-2105
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] Applicability of a high-resolution small semiconductor gamma camera to small animal imaging. Applicability of a high-resolution small semiconductor gamma camera to small animal imaging.2007
- Author(s)
  Kiyono Y., Kawashima H., Magata Y., et al.
- Journal Title
  
  Nucl. Med. Commun. 28
  
  Pages: 736-741
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] Extensive FDG uptake and its modification with corticosteroid in a granuloma rat model : An experimental study for differentiating granuloma from tumors.2007
- Author(s)
  Zhao S., Kuge Y., Kohanawa M, Takahashi T., Kawashima H., Temma T., Takei T., Zhao Y., Seki K., Tamaki N.
- Journal Title
  
  Eur. J. Nucl. Med. Mol. Imaging 34
  
  Pages: 2096-2105
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] Applicability of a high-resolution small semiconductor gamma camera to small animal imaging.2007
- Author(s)
  Kiyono Y., Kuge Y., Katada Y., Kawashima H., Magata Y., Saji H.
- Journal Title
  
  Nucl Med. Commun. 28
  
  Pages: 736-741
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] Radio-iodinated VEGF to image tumor angiogenesis in a LS180 tumor xenograft model.2006
- Author(s)
  Yoshimoto M., Kinuya S., Kawashima A., Nishii R., Yokoyama K., Kawai K.
- Journal Title
  
  Nucl. Med. Biol. 33
  
  Pages: 963-969
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] Change of central cholinergic receptors following lesions of nucleus basalis magnocellularis in rats : Search for an imaging index suitable for the early detection of Alzheimer's disease.2006
- Author(s)
  Ogawa M., Kawashima H., Magata Y., et al.
- Journal Title
  
  Nucl. Med. Biol. 33
  
  Pages: 249-254
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] Estimation of oxygen metabolism in a rat model of permanent ischemia using positron emission tomography with injectable ^<15>O-O_2.2006
- Author(s)
  Temma T., Magata Y., Kuge Y., Shimonaka S., Sano K., Katada Y., Kawashima H., Mukai T., Watabe H., lida H., Saji H.
- Journal Title
  
  J. Cereb. Blood Flow Metab. 26
  
  Pages: 1577-1583
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] Change of central cholinergic receptors following lesions of nucleus basalis magnocellularis in rats : Search for an imaging index suitable for the early detection of Alzheimer's disease.2006
- Author(s)
  Ogawa M., Iida Y, Nakagawa M., Kuge Y., Kawashima H., Tominaga A., Ueda M., Magata Y., Saji H.
- Journal Title
  
  Nucl. Med Biol. 33
  
  Pages: 249-254
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390329
[Journal Article] Estimation of oxygen metabolism in a rat model of permanent ischemia using positron emission tomography with injectable^<15>O-O_2.2006
- Author(s)
  Temma T., Magata Y., Kawashima H., et al.
- Journal Title
  
  J. Cereb. Blood Flow Metab. 26
  
  Pages: 1577-1583
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390329
[Patent] ベンゾチアゾール誘導体含有診断用組成物2009
- Inventor(s)
  佐治英郎, 小野正博, 河嶋秀和, 木村寛之
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2009-037773
- Filing Date
  2009-02-20
- Data Source
  KAKENHI-PROJECT-19209041
[Patent] コンフォメーション病診断のための組成物2009
- Inventor(s)
  佐治英郎、小野正博、木村寛之、河嶋秀和
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2009-222156
- Acquisition Date
  2009-09-28
- Data Source
  KAKENHI-PROJECT-19209041
[Patent] アゼチジニルメトキシピリミジン誘導体の製造法及びその使用2009
- Inventor(s)
  佐治英郎、木村寛之、小野正博、河嶋秀和、森大輔、原田直弥
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2009-228646
- Acquisition Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] 膵β細胞 GLP-1 受容体を標的とする PET 用イメージングプローブとしての18^F 標識 Exendin-4 誘導体の開発2012
- Author(s)
  小川祐, 木村寛之, 河嶋秀和, 豊田健太郎,向英理, 藤本裕之, 松田洋和, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] 膵β細胞 GLP-1受容体を標的とする SPECT 用イメージングプローブの開発2011
- Author(s)
  小川祐, 木村寛之, 河嶋秀和, 豊田健太郎, 向英里, 藤本裕之, 平尾佳, 松田洋和, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Synthesis and evaluation of radioiodinated exendin derivatives for the imaging of GLP-1 receptor expression in pancreatic islets2011
- Author(s)
  Kimura H, Ogawa Y, Kawashima H, Mukai E, Toyoda K, Fujimoto H, Hirao K, Ono M, Inagaki N, Saji H
- Organizer
  Society of Nuclear Medicine 57th Annual Meeting
- Place of Presentation
  Salt Lake City
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] 膵β細胞 GLP-1 受容体標的放射性プローブとしての I-123 標識Exendin-4 誘導体2011
- Author(s)
  小川祐, 木村寛之, 河嶋秀和, 豊田健太郎,向英理, 藤本裕之, 松田洋和, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第9回次世代を担う若手のためのフィジカル・ファーマフォーラム(PPF2011)
- Place of Presentation
  箱根
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] 膵β細胞GLP-1受容体を標的とするSPECT用イメージングプローブの開発2011
- Author(s)
  小川祐、木村寛之、河嶋秀和、豊田健太郎、向英里、藤本裕之、平尾佳、松田洋和、小野正博、稲垣暢也、佐治英郎
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市、グランシップ
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] 膵β細胞 GLP-1 受容体を標的とする SPECT 用イメージングプローブ Exendin(9-39)誘導体の開発2011
- Author(s)
  小川祐, 木村寛之, 河嶋秀和, 豊田健太郎,向英理, 藤本裕之, 松田洋和, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第51回日本核医学会学術総会
- Place of Presentation
  筑波
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Synthesis and evaluation of F-18 labeled peptidergic compound as a novel tumor peptide transporter imaging probe2010
- Author(s)
  Kawashima H, Toshikawa K, Mori D, Kimura H, Ono M, Saji H
- Organizer
  2010 Society of Nuclear Medicine
- Place of Presentation
  Salt Lake City(USA)
- Year and Date
  2010-06-08
- Data Source
  KAKENHI-PROJECT-22790035
[Presentation] Non-Invasive PET Imaging of Pancreatic Islets Targeting Glucagon-Like Peptide-1 Receptors2010
- Author(s)
  Toyoda K, Kimura H, Mukai E, Fujimoto H, Ogawa Y, Kawashima H, Ueda M, Temma T, Hirao K, Nagakawa K, Seino Y, Saji H, Inagaki N
- Organizer
  8th IDF WPR Congress
- Place of Presentation
  Busan, Korea
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Synthesis and evaluation of F-18 labeled peptidergic compound as a novel tumor peptide transporter imaging probe2010
- Author(s)
  Kawashima H, Toshikawa K, et al.
- Organizer
  2010 Society of Nuclear Medicine
- Place of Presentation
  Salt Palace Convention Center (Salt Lake City)
- Year and Date
  2010-06-08
- Data Source
  KAKENHI-PROJECT-22790035
[Presentation] SUR1受容体を標的とした膵β細胞イメージング用放射性プローブの開発2010
- Author(s)
  松田洋和、木村寛之、小川祐、河嶋秀和、豊田健太郎、向英里、藤本裕之、平尾佳、小野正博、稲垣暢也、佐治英郎
- Organizer
  第50回日本核医学会学術総会
- Place of Presentation
  さいたま市、大宮ソニックシティ
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] SUR1 受容体を標的とした膵β細胞イメージング用放射性プローブの開発2010
- Author(s)
  松田洋和, 木村寛之, 小川祐, 河嶋秀和, 豊田健太郎, 向英里, 藤本裕之, 平尾佳, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第50回日本核医学会学術総会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Synthesis and evaluation of radioiodinated exendin derivatives for the imaging of GLP-1 receptor expression in pancreatic islets.2010
- Author(s)
  Kimura H, Ogawa Y, Kawashima H, Mukai E, Toyoda K, Fujimoto H, Hirao K, Ono M, Inagaki N, Saji H
- Organizer
  Society of Nuclear Medicine 57^<th> Annual Meeting
- Place of Presentation
  Salt Lake City, USA
- Year and Date
  2010-06-08
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Microwaveを利用した^<99m>TcまたはReトリカルボニル錯体の迅速合成法の検討2010
- Author(s)
  森大輔、木村寛之、河嶋秀和, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山県桃太郎アリーナ(岡山)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] GLP-1 受容体を標的とする放射性ヨウ素標識イメージングプローブの開発2010
- Author(s)
  小川祐, 木村寛之, 河嶋秀和, 豊田健太郎, 向英里, 藤本裕之, 平尾佳, 松田洋和, 小野正博, 稲垣暢也, 佐治英郎
- Organizer
  第50回日本核医学会学術総会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] Non-Invasive PET Imaging of Pancreatic Islets Targeting Glucagon-Like Peptide-1 Receptors2010
- Author(s)
  Toyoda K, Kimura H, Mukai E, Fujimoto H, Ogawa Y, Kawashima H, Ueda M, Temma T, Hirao K, Nagakawa K, Seino Y, Saji H, Inagaki N
- Organizer
  American Diabetes Association 70th Scientific Sessions
- Place of Presentation
  Orland, USA
- Year and Date
  2010-06-28
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] GLP-1受容体を標的とする放射性ヨウ素標識イメージングプローブの開発2010
- Author(s)
  小川祐、木村寛之、河嶋秀和、豊田健太郎、向英里、藤本裕之、平尾佳、松田洋和、小野正博、稲垣暢也、佐治英郎
- Organizer
  第50回日本核医学会学術総会
- Place of Presentation
  さいたま市、大宮ソニックシティ
- Data Source
  KAKENHI-PROJECT-22249046
[Presentation] A novel radioiodinated hydroxyethylamine dipeptide isoster derivative as potential SPECT imaging probe for β-secretase detection in Alzheimer's disease brain2009
- Author(s)
  Kawashima H, Kawai T, Kimura H, et al.
- Organizer
  2009 Society of Nuclear Medicine
- Place of Presentation
  Metro Toronto Convention Centre(Toronto, Canada)
- Year and Date
  2009-06-14
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] アルツハイマー病における脳内β-セクレターゼイメージングを目的としたhydroxyethylamine dipeptide isoster誘導体の合成と評価2009
- Author(s)
  河合知喜、河嶋秀和、木村寛之、小野正博、佐治英郎
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19790867
[Presentation] アルツハイマー病における脳内β-セクレターゼイメージングを目的としたhydroxyethylamine dipeptide isoster誘導体の合成と評価2009
- Author(s)
  河合知喜, 河嶋秀和, 木村寛之, 小野正博, 佐治英郎
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] 多機能性βアミロイドイメージングプローブの開発を目的としたベンゾチアソール誘導体の合成と評価2009
- Author(s)
  林瞬, 小野正博, 木村寛之, 河嶋秀和, 中山守雄, 佐治英郎
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] [^<11>C]Galanthamineの合成と脳内分布評価2009
- Author(s)
  小川祐, 河合知喜, 木村寛之, 河嶋秀和, 濱島好男, 野出學, 小野正博, 佐治英郎
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] A Novel Non-peptidergic Tracer for PET Imaging of BACE1 Density in Alzheimer's Disease Brain2008
- Author(s)
  Kawashima H, Kawai T, Kuge Y, Saji H
- Organizer
  2008 World Molecular Imaging Congress
- Place of Presentation
  Nice(France)
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19790867
[Presentation] アルツハイマー病における脳内β-セクレターゼイメージングを目的としたhydroxyethylamine dipeptide isoster誘導体の標識合成2008
- Author(s)
  河合知喜、河嶋秀和、木村寛之、久下裕司、佐治英郎
- Organizer
  日本分子イメージング学会第4回学術総会
- Place of Presentation
  埼玉
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19790867
[Presentation] A Novel Non-peptidergic Tracer for PET Imaging of BACE1 Density in Alzheimer's Disease Brain2008
- Author(s)
  Kawashima H, Kawai T, Kuge Y, Saji H, et al.
- Organizer
  World Molecular Imaging Congress
- Place of Presentation
  Nice
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] A Novel Non-peptidergic Tracer for PET Imaging of BACEl Density in Alzheimer's Disease Brain2008
- Author(s)
  Kawashima H, Kawai T, Kuge Y, Saji H
- Organizer
  2008 World Molecular Imaging Congress
- Place of Presentation
  Nice (France)
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] アルツハイマー病における脳内β-セクレクーゼイメージングを目的としたhydroxyethylamine dipeptide isoster誘導体の標識合成2008
- Author(s)
  河合知喜, 河嶋秀和, 木村寛之, 久下裕司, 佐治英郎
- Organizer
  日本分子イメージング学会第4回学術総会
- Place of Presentation
  埼玉
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] A novel low molecular weight radiotracer for apoptosis imaging: radioiodinated isatin sulfonamide targeting2007
- Author(s)
  Kawashima H.
- Organizer
  2007 The Society of Nuclear Medicine Annual Meeting
- Place of Presentation
  Washington D.C.
- Year and Date
  2007-06-06
- Data Source
  KAKENHI-PROJECT-19209041
[Presentation] Estimation of oxygen metabolism with injectable ^<15>O-O_2 in a rat model of permanent cerebral ischemia.2005
- Author(s)
  Temma T., Magata Y., Kawashima H., et al.
- Organizer
  The Society of Nuclear Medicine 52nd Annual Meeting
- Place of Presentation
  Toronto, Canada
- Year and Date
  2005-06-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390329
[Presentation] Estimation of Oxygen Metabolism with Injectable ^<15>O-O2 in a Rat Model of Permanent Cerebral Ischemia.2005
- Author(s)
  Temma T,. Magata Y., Kuge Y., Kawashima H,. Mukai T., Ueda M., Ogawa M., Watabe H., Iida H., Saji H.
- Organizer
  The Society of Nuclear Medicine 52nd Annual Meeting
- Year and Date
  2005-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390329
[Presentation] Estimation of Oxygen Metabolism with Injectable ^<15>O-O_2 in a Rat Model of Permanent Cerebral Ischemia.2005
- Author(s)
  Tenuna T., Magata Y., Kuge Y., Kawashima H., Mukai T., Ueda M., Ogawa M., Watabe H., Iida H., Saji H.
- Organizer
  The Society of Nuclear Medicine 52nd Annual Meeting, Jun.
- Year and Date
  2005-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390329
[Presentation] The hybrid PET and MR imaging of cerebral hemodynamids in rats with hypoxic-ischemic brain injury
- Author(s)
  Makiko Ohsima, Jun-ichiro Enmi, Masahiro Tsuji, Tetsuaki Moriguchi, Hajime Fukuda, Yoshiko Hashikawa, Tsutomu Zeniya, Hidekazu Kawashima, Kazuhiro Koshino, Hidehiro Iida.
- Organizer
  XIII Turku PET Symposium
- Place of Presentation
  Turku PET Center (Finland)
- Year and Date
  2014-05-24 – 2014-05-27
- Data Source
  KAKENHI-PROJECT-25871237
[Presentation] In vivo imaging-supported development of an intraluminal suture-based technique.
- Author(s)
  Jun‐ichiro Enmi1, Yoshiko Hashikawa, Hajime Fukuda, Tetsuaki Moriguchi, Makiko Ohshima, Kazuhiro Koshino, Hidekazu Kawashima, Tsutomu Zeniya, Masahiro Tsuji, Hidehiro Iida
- Organizer
  World Molecular Imaging Congress (WMIC2014)
- Place of Presentation
  COEX Convention Center (Soul, Korea)
- Year and Date
  2014-09-17 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25871237
[Presentation] ハイブリッドPET/MR システムによるラット脳梗塞巣に集積する貪食細胞のイメージング
- Author(s)
  大嶌麻妃子、河嶋　秀和、銭谷　勉、越野　一博、圓見　純一郎、森口　哲朗、辻　雅弘、飯田　秀博
- Organizer
  第９回分子イメージング学会総会・学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府）
- Year and Date
  2014-05-22 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-25871237

1. SAJI Hideo (40115853)

# of Collaborated Projects: 6 results

# of Collaborated Products: 21 results
2. TEMMA Takashi (90378787)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
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# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
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# of Collaborated Projects: 3 results

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# of Collaborated Projects: 3 results

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# of Collaborated Projects: 2 results

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# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
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27. ISHIDA Yasushi (20212897)

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28. MAGATA Yasuhiro (20209399)

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29. ARAKI Norio (20362486)

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# of Collaborated Projects: 1 results

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60. 向英里

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61. 稲垣暢也

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Kawashima Hidekazu 河嶋 秀和

河嶋 秀和 カワシマ ヒデカズ

KAWASHIMA HIDEKAZU 河嶋 秀和

KAWASHIMA Hidekazu 河嶋 秀和

河島 秀和 カワシマ ヒデカズ

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Co-Researchers

スカベンジャー受容体のイメージングに基づく生活習慣病および悪性腫瘍の評価Principal InvestigatorOngoing

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Development of exosome-capturing antibody-conjugated nucleic acid medicines against multiple myelomaOngoing

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Development of 125I-labeled probe for the detection of macrophage-like cells in inflammatory lesionPrincipal Investigator

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Synthesis and evaluation of an in vivo imaging probe for tumor based on the intracellular transporting systemPrincipal Investigator

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Development of a brain β-secretase imaging probe for the very early detection of Alzheimer's diseasePrincipal Investigator

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Kawashima Hidekazu 河嶋秀和

河嶋秀和カワシマヒデカズ

KAWASHIMA HIDEKAZU 河嶋秀和

KAWASHIMA Hidekazu 河嶋秀和

河島秀和カワシマヒデカズ