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HAGA Hisashi  芳賀 永

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Researcher Number 00292045
Other IDs
Affiliation (Current) 2023: 北海道大学, 先端生命科学研究院, 教授
Affiliation (based on the past Project Information) *help 2016 – 2022: 北海道大学, 先端生命科学研究院, 教授
2013 – 2015: 北海道大学, 先端生命科学研究科(研究院), 教授
2014: 北海道大学, 先端生命科学研究科, 教授
2014: 北海道大学, 大学院先端生命科学研究院, 教授
2012: 北海道大学, 先端生命科学研究科(研究院), 准教授 … More
2012: 北海道大学, 先端生命科学研究科, 准教授
2012: 北海道大学, 大学院・生命科学院, 准教授
2010 – 2012: 北海道大学, 大学院・先端生命科学研究院, 准教授
2010: 北海道大学, 大学院・先端生命, 准教授
2007 – 2010: Hokkaido University, Graduate School of Science, Associate Professor
2009: 北海道大学, 大学院・理学研究科, 准教授
2006: 北海道大学, 大学院理学研究院, 助教授
2002 – 2004: 北海道大学, 大学院・理学研究科, 助教授
2002: 北海道大学, 大学院・理学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Tumor biology / Cell biology / Biophysics / Science and Engineering / Basic Section 50010:Tumor biology-related
Except Principal Investigator
Radiation science / Biological Sciences / Bioinformatics/Life informatics / Biophysics/Chemical physics … More / Structural biochemistry / Biophysics / Dynamics/Control / Basic Section 57040:Regenerative dentistry and dental engineering-related Less
Keywords
Principal Investigator
細胞・組織 / 集団運動 / コラーゲンゲル / がん細胞 / 上皮細胞 / 細胞運動 / メカノセンス / ゲル基質 / 上皮細胞シート / 電子顕微鏡 … More / 集団浸潤 / 走査型プローブ顕微鏡 / 結合組織 / 組織形成 / 細胞培養 / 集団性 / 接着構造 / 上皮管腔組織 / メカノセンシング / 浸潤 / 炎症性反応 / 転写調節因 / 転写調節因子 / 粘弾性培養基質 / 腸管絨毛構造 / 自己組織化 / アクトミオシン / 粘弾性基質 / ゾル基質 / 接触追従 / 細胞間接着構造 … More
Except Principal Investigator
細胞 / 細胞運動 / ミオシン / 走査型プローブ顕微鏡 / 放射線生物学 / irradiation / 放射線治療 / p53 / apoptosis / ATF5 / 形態形成 / 3次元 / 折り紙 / 回転 / 数理モデル / シミュレ―ション / 折り畳み / シミュレーション / 3次元 / 物理計測 / 三次元 / 発生 / システム / 力学平衡 / ホメオスタシス / リン酸化 / 細胞コロニー / 力学的応答 / 力学的メモリー効果 / p16 / repopulation / mitosis / MMP / HIF1-alpha / radiation / cancer stem cell / cell movement / Radiotherapy / TGFB-1 / 細胞形態 / 動体追跡 / 医学研究 / 生体の動き / 細胞遊走 / 胃癌 / 低酸素細胞 / 量子線シミュレーション / 電子線トラック解析 / モンテカルロ法 / プラスチック檢出器 / 体幹部定位放射線照射 / 非線形最適化 / プラスチック検出器 / X線結晶解析 / タンパク質結晶化 / アクチン / メカノセンシティビティ / メカノセンサー / 構造多型性 / 細胞極性 / MDシミュレーション / 蛍光プローブ / UTR / HIF / HIF-1a / trascription / translation / 低酸素 / HIF/alpha / 粘弾性 / 生体 / AFM / カンチレバー / フォースモジュレーション法 / 表面剛性 / 表面粘性 / visco-eleastic / cell / living material / atomic force microscopy / 放射線 / 放射線感受性 / 転写因子 / radiosensitivity / transcription factor / 3D形態形成 / クチクラ / 培養細胞の回転 / 昆虫 / 体節 / 外骨格 / 力学 / 3D形態 / メカノバイオロジー / システムバイオロジー / 3D形態形成 / カブトムシ / 形態 / 3D / 数理 / 工学 / CTスキャン / 班会議 / 合宿 / 3D / 計算科学 / 物理測定 / バーチャル研究所 / 数理生物学 / 口腔粘膜上皮細胞 / メカノトランスダクション / 足場材 / ヤング率 / 上皮角化 / 硬さ / 口腔ケラチノサイト / 遺伝子発現 / 運動能 / 口腔粘膜 / 角化 / 足場材硬さ Less
  • Research Projects

    (20 results)
  • Research Products

    (168 results)
  • Co-Researchers

    (112 People)
  •  Investigation of cell-cell adhesion structures and signaling pathways causing collective invasion in cancer cellsPrincipal Investigator

    • Principal Investigator
      芳賀 永
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Hokkaido University
  •  足場材の硬さの違いを利用した上皮角化・非角化様式解明と培養口腔粘膜作成法への応用

    • Principal Investigator
      泉 健次
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57040:Regenerative dentistry and dental engineering-related
    • Research Institution
      Niigata University
  •  The mechanism of contact following inducing cancer collective invasion and the verification of universalityPrincipal Investigator

    • Principal Investigator
      Haga Hisashi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Hokkaido University
  •  3D morphogenesis of epithelial cell sheets in vitroPrincipal Investigator

    • Principal Investigator
      Haga Hisashi
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Virtual laboratory to accelerate international collaboration on 3D morphological logic

    • Principal Investigator
      Kondo Shigeru
    • Project Period (FY)
      2015 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  3D morphologic

    • Principal Investigator
      Kondo Shigeru
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Stiff Substrates Enhances ATF5-Signaling-Mediated Invasive Ability in Cancer CellsPrincipal Investigator

    • Principal Investigator
      HAGA HISASHI
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Hokkaido University
  •  ゲル基質の軟らかさと粘性を利用した上皮シートの3次元組織構築Principal Investigator

    • Principal Investigator
      芳賀 永
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Hokkaido University
  •  多数の細胞の力と運動がもたらす管腔構造形成のロジックPrincipal Investigator

    • Principal Investigator
      芳賀 永
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Tension-induced conformational changes of actin filaments and their influence on actin binding and intracellular localization of myosin.

    • Principal Investigator
      UYEDA Taro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biophysics
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  がん細胞は自身の生存をかけ放射線域を逃れるべく上皮間葉移行をなしうるか

    • Principal Investigator
      西岡 健
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Hokkaido University
  •  Research for Real-time Tracking Medical Science

    • Principal Investigator
      SHIRATO Hiroki
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Radiation science
    • Research Institution
      Hokkaido University
  •  Collective migration of epithelial cells induced by softness of substratesPrincipal Investigator

    • Principal Investigator
      HAGA Hisashi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      Hokkaido University
  •  力学的応答測定を利用した極微小タンパク質結晶の判別・評価法の開発

    • Principal Investigator
      田中 勲
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Structural biochemistry
    • Research Institution
      Hokkaido University
  •  The secret of radiation-surviving cell : multidisciplinary approach to eradicate cancer

    • Principal Investigator
      NISHIOKA Takeshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Hokkaido University
  •  Mechanical memory effect of cells in colony

    • Principal Investigator
      KAWABATA Kazushige
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biophysics/Chemical physics
    • Research Institution
      Hokkaido University
  •  Radiation-induced highly-malignant cancer cells: the mechanism and how to deal with it

    • Principal Investigator
      NISHIOKA Takeshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Hokkaido University
  •  細胞システムにおける「力学平衡」モデルの実証

    • Principal Investigator
      KAWABATA Kazushige
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      Hokkaido University
  •  ナノ力学プローブ顕微鏡による結合組織の形成過程における力学的制御機構の解明Principal Investigator

    • Principal Investigator
      芳賀 永
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cell biology
    • Research Institution
      Hokkaido University
  •  Quantitative evaluation of visco-elastic distribution of living cells using scanning probe microscopy

    • Principal Investigator
      HIRAI Yoshihiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dynamics/Control
    • Research Institution
      Osaka Prefecture University

All 2022 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] 三次元培養における培養手法と周辺技術動向2019

    • Author(s)
      石原 誠一郎、芳賀 永
    • Total Pages
      197
    • Publisher
      情報機構
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Book] 医学のあゆみ2019

    • Author(s)
      芳賀 永
    • Total Pages
      70
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Book] 三次元培養における培養手法と周辺技術動向2019

    • Author(s)
      石原 誠一郎,芳賀 永
    • Total Pages
      197
    • Publisher
      情報機構
    • ISBN
      9784865021684
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Book] Chromosome Nanoscience and Technology2007

    • Author(s)
      K. Kawabata, K. Nomura, K. Ikeda. O. Hoshi, D. Fukushi, H. Haga and T. Ushiki
    • Publisher
      Taylor & Francis Group
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Matrix Stiffness Contributes to Cancer Progression by Regulating Transcription Factors2022

    • Author(s)
      Seiichiro Ishihara, Hisashi Haga
    • Journal Title

      Cancers

      Volume: 14 Pages: 1049-1049

    • DOI

      10.3390/cancers14041049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KK0234, KAKENHI-PROJECT-21K07142
  • [Journal Article] Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice2019

    • Author(s)
      Acebedo AR, Suzuki K, Hino S, Alcantara MC, Sato Y, Haga H, Matsumoto KI, Nakao M, Shimamura K, Takeo T, Nakagata N, Miyagawa S, Nishinakamura R, Adelstein RS, Yamada G.
    • Journal Title

      Commun Biol.

      Volume: eCollection Pages: 95-95

    • DOI

      10.1038/s42003-019-0336-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06837, KAKENHI-PROJECT-18K19479, KAKENHI-PLANNED-17H06432, KAKENHI-PROJECT-18H02618, KAKENHI-PROJECT-16K07215, KAKENHI-PROJECT-16K07375, KAKENHI-PROJECT-18K06938, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-PLANNED-15H05858, KAKENHI-PROJECT-18H02474
  • [Journal Article] The intercellular expression of type-XVII collagen, laminin-332, and integrin-b1 promote contact following during the collective invation of a cancer cell population2019

    • Author(s)
      Yuji Kumagai, Junko Nio-Kobayashi, Sumire Ishida-Ishihara, Hiromi Tachibana, Ryosuke Omori, Atsushi Enomoto, Seiichiro Ishihara, Hisashi Haga
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 514 Pages: 1115-1121

    • DOI

      10.1016/j.bbrc.2019.05.058

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07150, KAKENHI-PROJECT-17K08502
  • [Journal Article] Modulation and Characterization of the Double Network Hydrogel Surface-Bulk Transition2019

    • Author(s)
      Frauenlob M, King DR, Guo H, Ishihara S, Tsuda M, Kurokawa T, Haga H, Tanaka S, Gong JP.
    • Journal Title

      Macromolecules

      Volume: 52 Pages: 6704-6713

    • DOI

      10.1021/acs.macromol.9b01399

    • NAID

      120006885161

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07059, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-PLANNED-15H05858, KAKENHI-PROJECT-17H06144
  • [Journal Article] Differential contributions of nonmuscle myosin IIA and IIB to cytokinesis in human immortalized fibroblasts2019

    • Author(s)
      Yamamoto K., Otomo K., Nemoto T., Ishihara S., Haga H., Nagasaki A., Murakami Y., Takahashi M.
    • Journal Title

      Experimental Cell Research

      Volume: 376 Pages: 67-76

    • DOI

      10.1016/j.yexcr.2019.01.020

    • NAID

      120006803950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06200, KAKENHI-PROJECT-18K06591, KAKENHI-PLANNED-15H05953, KAKENHI-PROJECT-16H06280, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-PLANNED-15H05858
  • [Journal Article] Long-term Culture of Human iPS Cell-derived Telencephalic Neuron Aggregates on Collagen Gel2018

    • Author(s)
      Oyama Hiroshi、Takahashi Koji、Tanaka Yoshikazu、Takemoto Hiroshi、Haga Hisashi
    • Journal Title

      Cell Structure and Function

      Volume: 43 Issue: 1 Pages: 85-94

    • DOI

      10.1247/csf.18002

    • NAID

      130006742880

    • ISSN
      0386-7196, 1347-3700
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856, KAKENHI-PLANNED-15H05858
  • [Journal Article] Anisotropic Multi-channel Collagen Gel (MCCG) Guides the Growth Direction of the Neurite-like Processes of PC12 Cells2018

    • Author(s)
      Koh Isabel、Furusawa Kazuya、Haga Hisashi
    • Journal Title

      Scientific Reports

      Volume: 8

    • DOI

      10.1038/s41598-018-32156-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856, KAKENHI-PLANNED-15H05858
  • [Journal Article] Glycosphingolipid GM2 Induces Invasiveness in Irradiation-tolerant Lung Cancer Cells2018

    • Author(s)
      Ishihara Seiichiro、Aoki Kei、Mizutani Takeomi、Amano Maho、Nishimura Shin-Ichiro、Haga Hisashi
    • Journal Title

      Cell Structure and Function

      Volume: 43 Issue: 2 Pages: 177-185

    • DOI

      10.1247/csf.18026

    • NAID

      130007507045

    • ISSN
      0386-7196, 1347-3700
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Journal Article] Girdin/GIV regulates collective cancer cell migration by controlling cell adhesion and cytoskeletal organization2018

    • Author(s)
      Wang Xiaoze、Enomoto Atsushi、Weng Liang、Mizutani Yasuyuki、Abudureyimu Shaniya、Esaki Nobutoshi、Tsuyuki Yuta、Chen Chen、Mii Shinji、Asai Naoya、Haga Hisashi、Ishida Sumire、Yokota Kenji、Akiyama Masashi、Takahashi Masahide
    • Journal Title

      Cancer Science

      Volume: 109 Pages: 3643-3656

    • DOI

      10.1111/cas.13795

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07150, KAKENHI-PROJECT-26221304
  • [Journal Article] Collective Movement and 3D Morphogenesis of Epithelial Cells Induced by Softness of the Extracellular Matrix2018

    • Author(s)
      芳賀 永
    • Journal Title

      Biophysics

      Volume: 58 Issue: 4 Pages: 196-199

    • DOI

      10.2142/biophys.58.196

    • NAID

      130007420830

    • ISSN
      0582-4052, 1347-4219
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856, KAKENHI-PLANNED-15H05858
  • [Journal Article] Mesenchymal Stem Cells in Breast Cancer: Response to Chemical and Mechanical Stimuli2017

    • Author(s)
      Ishihara S., Ponik S. M., Haga H.
    • Journal Title

      Oncoscience

      Volume: 4 Pages: 158-159

    • DOI

      10.18632/oncoscience.381

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Journal Article] Mathematical model of collective cell migrations based on cell polarity2017

    • Author(s)
      M. Akiyama, T. Sushida, S. Ishida, H. Haga
    • Journal Title

      Development, Growth & Differentiation

      Volume: 59 Pages: 471-490

    • DOI

      10.1111/dgd.12381

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-INTERNATIONAL-15K21726, KAKENHI-PLANNED-15H05857, KAKENHI-PLANNED-15H05858, KAKENHI-PROJECT-17J06276, KAKENHI-ORGANIZER-15H05856
  • [Journal Article] Data Set for Comparison of Cellular Dynamics between Human AAVS1 Locus-modified and Wild-type Cells2016

    • Author(s)
      Takeomi Mizutani, Hisashi Haga, Kazushige Kawabata
    • Journal Title

      Data in Brief

      Volume: 6 Pages: 793-798

    • DOI

      10.1016/j.dib.2015.12.053

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15010, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-25287106, KAKENHI-PLANNED-15H05858, KAKENHI-PROJECT-26430104, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856
  • [Journal Article] Role of ATF5 in the Invasive Potential of Diverse Human Cancer Cell Lines2016

    • Author(s)
      Akihiro Nukuda, Hiroki Endoh, Motoaki Yasuda, Takeomi Mizutani, Kazushige Kawabata, Hisashi Haga
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 474(3) Pages: 509-514

    • DOI

      10.1016/j.bbrc.2016.04.131

    • NAID

      120006219898

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25287106, KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-15K15010
  • [Journal Article] Conformational plasticity of JRAB/MICAL-L2 provides 'law and order in collective cell migration2016

    • Author(s)
      A. Sakane, S. Yoshizawa, M. Nishimura, Y. Tsuchiya, N. Matsushita, K. Miyake, K. Horikawa, I. Imoto, C. Mizuguchi, H. Saito, T. Ueno, S. Matsushita, H. Haga, S. Deguchi, K. Mizuguchi, H.
    • Journal Title

      Mol. Biol. Cell

      Volume: 27 Pages: 3095-3108

    • DOI

      10.1091/mbc.e16-05-0332

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05858, KAKENHI-PLANNED-15H05954, KAKENHI-PROJECT-15H03004, KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-26460370, KAKENHI-PROJECT-15K15084, KAKENHI-PROJECT-16K12872, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-ORGANIZER-15H05856
  • [Journal Article] Receptor activator of NF-κB ligand induces cell adhesion and integrin α2 expression via NF-κB in head and neck cancers.2016

    • Author(s)
      T.Yamada, M. Tsuda, T. Wagatsuma, Y. Fujioka, M. Fujioka, A. O. Satoh, K. Horiuchi, S. Nishide, A. Nanbo, Y. Totsuka, H. Haga, S. Tanaka, M. Shindoh, and Y. Ohba
    • Journal Title

      SCIENTIFIC REPORTS

      Volume: 6 Pages: 1-16

    • DOI

      10.1038/srep23545

    • NAID

      120005753715

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-26460545, KAKENHI-PROJECT-15K15106, KAKENHI-PUBLICLY-26115701, KAKENHI-PROJECT-26670414, KAKENHI-PROJECT-26860254, KAKENHI-PROJECT-26861539, KAKENHI-PUBLICLY-15H01248, KAKENHI-PROJECT-26293041, KAKENHI-PROJECT-15K15023, KAKENHI-PROJECT-15KK0290
  • [Journal Article] Compressive Stress Induces Dephosphorylation of the Myosin Regulatory Light Chain via RhoA Phosphorylation by the Adenylyl Cyclase/Protein Kinase A Signaling Pathway2015

    • Author(s)
      Takemoto, T., Ishihara, S., Mizutani, T., Kawabata, K., Haga, H.
    • Journal Title

      PLoS ONE

      Volume: 10

    • DOI

      10.1371/journal.pone.0117937

    • NAID

      120005613567

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-25127701, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-26430104, KAKENHI-PUBLICLY-26106702
  • [Journal Article] Three-dimensional morphogenesis of MDCK cells induced by cellular contractile forces on a viscous substrate2015

    • Author(s)
      Misako Imai, Kazuya Furusawa, Takeomi Mizutani, Kazushige Kawabata, Hisashi Haga
    • Journal Title

      Scientific Reports

      Volume: 5 Pages: 14208-14208

    • DOI

      10.1038/srep14208

    • NAID

      120005682122

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15010, KAKENHI-PROJECT-15K16330, KAKENHI-PLANNED-15H05858, KAKENHI-PUBLICLY-26106703, KAKENHI-PROJECT-25287106, KAKENHI-PUBLICLY-26106702, KAKENHI-ORGANIZER-15H05856
  • [Journal Article] Stiff substrates increase YAP-signaling-mediated matrix metalloproteinase-7 expression.2015

    • Author(s)
      A. Nukuda, C. Sasaki, S. Ishihara, T. Mizutani, K. Nakamura, T. Ayabe, K. Kawabata, and H. Haga
    • Journal Title

      Oncogenesis

      Volume: 4

    • DOI

      10.1038/oncsis.2015.24

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-26462831, KAKENHI-PROJECT-25287106
  • [Journal Article] Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K2015

    • Author(s)
      N. Yamaguchi, T. Mizutani, K. Kawabata, and H. Haga
    • Journal Title

      Scientific Reports

      Volume: 5 Pages: 7656-7656

    • DOI

      10.1038/srep07656

    • NAID

      120005567742

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25127701, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-26430104, KAKENHI-PUBLICLY-26106702
  • [Journal Article] Activating Transcription Factor 5 Enhances Radioresistance and Malignancy in Cancer Cells2015

    • Author(s)
      S. Ishihara, M. Yasuda, A. Ishizu, M. Ishikawa, H. Shirato, and H. Haga
    • Journal Title

      Oncotarget

      Volume: 6 Pages: 4602-4614

    • NAID

      120005613573

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430104
  • [Journal Article] Transgene integration into the human AAVS1 locus enhances myosin II-dependent contractile force by reducing expression of myosin binding subunit 852015

    • Author(s)
      T. Mizutani, R. Li, H. Haga, and K. Kawabata
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 465 Pages: 270-274

    • DOI

      10.1016/j.bbrc.2015.08.018

    • NAID

      120005906854

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-15K15010, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-25287106, KAKENHI-PUBLICLY-26106702, KAKENHI-ORGANIZER-15H05856
  • [Journal Article] Filamin B Enhances the Invasiveness of Cancer Cells into 3D Collagen Matrices2015

    • Author(s)
      Y. Iguchi, S. Ishihara, Y. Uchida, K. Tajima, T. Mizutani, K. Kawabata, and H. Haga
    • Journal Title

      Cell Structure and Function

      Volume: 40 Issue: 2 Pages: 61-67

    • DOI

      10.1247/csf.15001

    • NAID

      130005086307

    • ISSN
      0386-7196, 1347-3700
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430104
  • [Journal Article] An Improved Glass Substrate for Cell Culture: Coating of Extracellular Matrix on a Glass Substrate by (3-aminopropyl)triethoxysilane Treatment2014

    • Author(s)
      Masuda, H.T., Ishihara, S., Harada, I., Mizutani, T., Ishikawa, M., Kawabata, K., Haga, H..
    • Journal Title

      BioTechniques

      Volume: 56 Pages: 172-179

    • DOI

      10.2144/000114156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106
  • [Journal Article] An Improved Method for Western Blotting When Extracting Proteins from Mammalian Cells Cultured on a Collagen Gel under Serum-free Conditions2014

    • Author(s)
      S.Ishihara, T.Mizutani, K.Kawabata, and H.Haga
    • Journal Title

      Cytotechnology

      Volume: 09 Jul. Pages: 1-8

    • NAID

      120005905602

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-26106702
  • [Journal Article] Modulation of extracellular conditions prevents the mutilayering of the simple epithelium.2014

    • Author(s)
      T. Mizutani, K. Takeda, H. Haga, M. Todo, K. Kawabata
    • Journal Title

      Histochem. Cell Biol.

      Volume: Vol. 141(5) Pages: 459-471

    • DOI

      10.1007/s00418-013-1176-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770167, KAKENHI-PUBLICLY-24106502, KAKENHI-PROJECT-24370069, KAKENHI-PROJECT-25287106
  • [Journal Article] An Improved Method for Western Blotting When Extracting Proteins from Mammalian Cells Cultured on a Collagen Gel under Serum-free Conditions2014

    • Author(s)
      S. Ishihara, M. Yasuda, A. Ishizu, M. Ishikawa, H. Shirato, H. Haga
    • Journal Title

      Cytotechnology

      Volume: 09 Jul Pages: 1-8

    • DOI

      10.1007/s10616-014-9766-4

    • NAID

      120005613573

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390285, KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106, KAKENHI-PROJECT-26430104
  • [Journal Article] Epithelial sheet folding induces lumen formation by Madin-Darby canine kidney cells in a collagen gel2014

    • Author(s)
      S. Ishida, R. Tanaka, N. Yamaguchi, G. Ogata, T. Mizutani, K. Kawabata, and H. Haga
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0099655

    • NAID

      120005476150

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106, KAKENHI-PUBLICLY-26106702
  • [Journal Article] Irradiation-tolerant Lung Cancer Cells Acquire Invasive Ability Dependent on Dephosphorylation of the Myosin Regulatory Light Chain2013

    • Author(s)
      S. Ishihara, M. Yasuda, T. Nishioka, T. Mizutani, K. Kawabata, H. Shirato and H. Haga
    • Journal Title

      FEBS Letters

      Volume: 587 Pages: 732-736

    • NAID

      120005228631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Journal Article] Lung cancer cells that survive ionizing radiation show increased integrin α2β1- and EGFR-dependent invasiveness.2013

    • Author(s)
      Xue Li, Seiichiro Ishihara, Motoaki Yasuda, Takeshi Nishioka, Takeomi Mizutani, Masayori Ishikawa, Kazushige Kawabata, Hiroki Shirato, Hisashi Haga
    • Journal Title

      PLoS One.

      Volume: 8(8) Pages: 1-12

    • DOI

      10.1371/journal.pone.0070905

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770167, KAKENHI-PUBLICLY-24106502, KAKENHI-PROJECT-24390285, KAKENHI-PROJECT-25287106
  • [Journal Article] Substrate stiffness regulates temporary NF-kB activation via actomyosin contractions.2013

    • Author(s)
      Seiichiro Ishihara, Motoaki Yasuda, Ichiro Harada, Takeomi Mizutani, Kazushige Kawabata, Hisashi Haga
    • Journal Title

      Exp. Cell Res.

      Volume: 319(19) Pages: 2916-2927

    • DOI

      10.1016/j.yexcr.2013.09.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770167, KAKENHI-PUBLICLY-24106502, KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106
  • [Journal Article] Irradiation-tolerant Lung Cancer Cells Acquire Invasive Ability Dependent on Dephosphorylation of the Myosin Regulatory Light Chain2013

    • Author(s)
      Ishihara S, Yasuda M, Nishioka T, Mizutani T, Kawabata K, Shirato H, Haga H
    • Journal Title

      FEBS Lett.

      Volume: 587(6) Pages: 732-6

    • DOI

      10.1016/j.febslet.2013.01.055

    • NAID

      120005228631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-23651099, KAKENHI-PROJECT-23770167, KAKENHI-PROJECT-24370069, KAKENHI-PROJECT-24390285
  • [Journal Article] Tempo-Spatial Change of Cellular Stiffness and Geometry in the Process of Developing Epithelial Cell-Cell Adhesion Measured by Atomic Force Microscopy2013

    • Author(s)
      R. Tanaka, T. Mizutani, H. Haga, and K. Kawabata
    • Journal Title

      pn. J. Appl. Phys. Conf. Proc.

      Volume: 1 Pages: 11004-11004

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-25127701
  • [Journal Article] The Number of Cyclic Stretch Regulates Cellular Elasticity in C2C12 Myoblasts2012

    • Author(s)
      Matsushima, A. & Tanaka, M.
    • Journal Title

      Open J. Cell Biol.

      Volume: 24 Pages: 1-10

    • DOI

      10.4236/cellbio.2012.11001

    • NAID

      120005090600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-23651099, KAKENHI-PROJECT-23770167, KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-24106502
  • [Journal Article] Relationship Between Diffusion-Weighted Magnetic Resonance Imaging and Histolog ical Tumor Grading of Hepatocellular Carcinoma2012

    • Author(s)
      Nakanishi M, Chuma M, Hige S, Omatsu T, Yokoo H, Nakanishi K, Kamiyama T, Kubota K, Haga H, Matsuno Y, Onodera Y, Kato M, Asaka M.
    • Journal Title

      Ann Surg Oncol

      Volume: 19 Pages: 1302-1309

    • DOI

      10.1245/s10434-011-2066-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-21390369
  • [Journal Article] Radiation-induced cancer cell repopulation : a possible mechanism implied by experiments using transplantable mouse-derived sarcoma cell line.2011

    • Author(s)
      Nishioka T, Yasuda M, Takeshima T, Haga H, Miyai Y, Shibata K, Yamazaki R, Shirato H, Teduka M, Date H.
    • Journal Title

      Cell Struct Funct. 36

      Pages: 13-20

    • NAID

      40019163767

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390319
  • [Journal Article] Radiation-induced Cancer Cell Repopulation : A possible mechanism implied by experiments using trasplantable mouse-derived sarcoma cell line2011

    • Author(s)
      T.Nishioka, M.Yasuda, T.Takeshima, H.Haga, Y.Miyai, K.Shibata, H.Shirato, M, Teduka, H.Date.
    • Journal Title

      Cell Structure and Function

      Volume: 36 Pages: 13-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Journal Article] Active fluctuation in the cortical cytoskeleton observed by high-speedlive-cell scanning probe microscopy2011

    • Author(s)
      K.Tamura, T.Mizutani, H.Haga, K.Kawabata
    • Journal Title

      Acta Biomaterialia

      Volume: 7 Pages: 3766-3772

    • DOI

      10.1016/j.actbio.2011.06.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-21570158, KAKENHI-PROJECT-23651099, KAKENHI-PROJECT-23770167
  • [Journal Article] Integrin betal-dependent invasive migration of irradiation-tolerant human lung adenocarcinoma cells in 3D collagen matrix.2010

    • Author(s)
      Ishihara S, Haga H, Yasuda M, Mizutani T, Kawabata K, Shirato H, Nishioka T.
    • Journal Title

      Biochem Biophys Res. 396

      Pages: 651-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390319
  • [Journal Article] Nano-mechanical Properties of Living Cells Expressing Constitutively Active RhoA Effectors2010

    • Author(s)
      K. Tamura, T. Mizutani, H. Haga, and K. Kawabata
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 403巻 Pages: 363-367

    • DOI

      10.1016/j.bbrc.2010.11.036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Journal Article] Integrin β1-dependent Invasive Migration of Irradiation-tolerant Human Lung Adenocarcinoma Cells in 3D Collagen Matrix2010

    • Author(s)
      S.Ishihara, H.Haga, M.Yasuda, T.Mizutani, K.Kawabata, H.Shirato, T.Nishioka
    • Journal Title

      Biochem.Biophys.Res.Commun.

      Volume: 396 Pages: 651-655

    • NAID

      120002223716

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Journal Article] Superselective high-dose cisplatin infusion with concomitant radiotherapy in patients with advanced cancer of the nasal cavity and paranasal sinuses : a single institution experience.2009

    • Author(s)
      Tsutsumi K, Tsuda M, Yazawa N, Nakamura H, Ishihara S, Haga H, Yasuda M, Yamazaki R, Shirato H, Kawaguchi H, Nishioka T
    • Journal Title

      Cell Structure and Function 34

      Pages: 86-96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390319
  • [Journal Article] Regulation of Cellular Contractile Force in Response t Mechanical Stretch by Diphosphorylation of Myosin Regulatory Light Chain via RhoA Signaling Cascade2009

    • Author(s)
      T. Mizutani, K.Kawabata, Y. Koyama, M. Takahashi, H. Haga
    • Journal Title

      Cell Motility and the Cytoskeleton (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Novel Function of Transcripion Factor ATF5 : Blockade of p53-dependent Apoptosis Induced by Ionizing Irradation2009

    • Author(s)
      T. Ni shioka, Y. Miyai, H. Haga, K. Kawabata, H. Shirato, A. Homma, K. Shibata and M. Yasuda
    • Journal Title

      Cell Structre and Function 34

      Pages: 17-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Regulation of Cellular Contractile Force in Response to Mechanical Stretch by Diphosphorylation of Myosin Regulatory Light Chain via RhoA Signaling Cascade2009

    • Author(s)
      T. Mizutani, K. Kawabata, Y. Koyama, M. Takahashi, and H. Haga
    • Journal Title

      Cell Motility and the Cytoskeleton

      Volume: 66巻 Pages: 389-397

    • DOI

      10.1002/cm.20378

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Journal Article] Nishioka T, Miyai Y, Haga H, Kawabata K, Shirato H, Homma A, Shibata K, and Yasuda M2009

    • Author(s)
      Nishioka T, Miyai Y, Haga H
    • Journal Title

      Cell Struct Funct 34

      Pages: 17-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390319
  • [Journal Article] Mechanical Response of Sinle Myoblasts to Various Stretching Patterns Visualized by Scanning Proe Microscoy2009

    • Author(s)
      W. Mitsui, K. Tamura, T. Mizutani,Haga and K. Kawabata
    • Journal Title

      Archivesof Histology and Cytology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Mechanical Response to Isotropic Shrinkage of Fibroblasts Measured by canning Probe Microscopy2008

    • Author(s)
      T. Kawamoto, H. Haga, K. Tamura, T.Mizutani and K. Kawabata
    • Journal Title

      Japanese Journal of Applied Physics 47

      Pages: 6173-6176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Collective Movement and Morphogenesis of Epithelial Cells2007

    • Author(s)
      H. Haga and K. Kawabata
    • Journal Title

      Proceedings of the international symposium on topological aspects of critical systems and netwrks

      Pages: 82-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Collective Movement and Morphogenesis of Epithelial Cells2007

    • Author(s)
      H. Haga
    • Journal Title

      Proceedings of the international symposium on topological aspects of critical systems and networks

      Pages: 82-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Visualization of stretch-induc intracellular teal response of single fibroblasts by mechanical scaning probe microscopy2007

    • Author(s)
      K. Tamura, T. Mizutani, H. Haga, K.Kawabata
    • Journal Title

      Japanese Journal of Applied Physics 46

      Pages: 5631-5635

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Development of a Device to Stretch Tissue-like Materials and to Measure Their Mechanical Properties by Scanning Probe Microscopy2007

    • Author(s)
      T. Mizutani, H. Haga, K. Kawabta
    • Journal Title

      Acta Biomaterialia 3

      Pages: 485-493

    • NAID

      120000971009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Imaging Mechanical Properties of Living Cells by Scanning Probe Microscoy2007

    • Author(s)
      H. Haga, M. Nagayama and K. Kawabata
    • Journal Title

      Crent Nanoscien 3

      Pages: 97-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Imaging Mechanical Properties of Living Cells by Scanning Probe Microscopy2007

    • Author(s)
      H. Haga
    • Journal Title

      Current Nanoscience 3

      Pages: 97-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] The Role of Actin-Binding Protein Filamin A in Cellular Stiffness and Morphology Studied by Wide-Range Scanning Probe Microscopy2006

    • Author(s)
      K. Kato, Y. Ohmori, T. Mizutani, H. Haga Kohashi, T. Ito, and K. Kawabata
    • Journal Title

      Japanese Journal of Applied Physics 45

      Pages: 2328-2332

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Observation of Stiff Domain Structure on Collagen Gels by Wide-Range Scanning Probe Microscopy2006

    • Author(s)
      T. Mizutani, H. Haga, K. Kato, K. Matsuda, and K. Kawabata
    • Journal Title

      Japanese Journal of Applied Physics 45

      Pages: 2353-2356

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Diphosphorylation of the Myosin Regulatory Light Chain Enhancs the Tension Acting on Stress Fibers in Fibroblasts2006

    • Author(s)
      T. Mizutani, H. Haga. Y. Koyama, M.Takahashi, K. Kawabata
    • Journal Title

      Journal of Cellular Physiology 209

      Pages: 726-731

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Journal Article] Collective Movement of Epithelial Cells on a Collagen Gel Substrate2005

    • Author(s)
      Hisashi Haga
    • Journal Title

      Biophys.J. 88

      Pages: 2250-2256

    • Data Source
      KAKENHI-PROJECT-14780536
  • [Journal Article] Collective Movement of Epithelial Cells on a Collagen Gel Substrate2005

    • Author(s)
      Hisashi Haga
    • Journal Title

      Biophys.J. 88

      Pages: 2250-2256

    • Data Source
      KAKENHI-PROJECT-15650051
  • [Patent] ゲルの製造方法及びコラーゲンゲル2018

    • Inventor(s)
      古澤 和也、芳賀 永、立花 真美
    • Industrial Property Rights Holder
      古澤 和也、芳賀 永、立花 真美
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-007402
    • Filing Date
      2018
    • Data Source
      KAKENHI-INTERNATIONAL-15K21726
  • [Presentation] STAT1活性化細胞により誘引される皮膚扁平上皮がんの集団浸潤2021

    • Author(s)
      熊谷 祐二, 小林 純子, 石原 誠一郎, 榎本 篤, 芳賀 永
    • Organizer
      患者由来がんモデル研究会2021
    • Data Source
      KAKENHI-PROJECT-21K07142
  • [Presentation] I型インターフェロン経路の亢進は扁平上皮がん由来サブクローン細胞の集団浸潤を引き起こす2021

    • Author(s)
      熊谷 祐二, 石原 誠一郎, 芳賀 永
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K07142
  • [Presentation] STAT1活性化は皮膚扁平上皮癌の集団浸潤を促進する2021

    • Author(s)
      熊谷 祐二, 小林 純子, 石原 誠一郎, 芳賀 永
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21K07142
  • [Presentation] がん細胞の集団浸潤:接触追従におけるintegrin-β1の機能解析2019

    • Author(s)
      熊谷 祐二,小林 純子,石原 誠一郎,芳賀 永
    • Organizer
      第56回 日本生化学会北海道支部例会
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] 球形の細胞シートでみられる細胞張力依存的な変形2019

    • Author(s)
      山村 芳央、石原 誠一郎、古澤 和也、芳賀 永
    • Organizer
      第56回 日本生化学会北海道支部例会
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] ゲル基質上の上皮細胞シートが引き起こす浸透圧勾配依存的なドーム形成2019

    • Author(s)
      石原(石田)すみれ、秋山 正和、須志田 隆道、古澤 和也、名黒 功、立野 浩輝、石原 誠一郎、芳賀 永
    • Organizer
      第56回 日本生化学会北海道支部例会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] Osmotic stimuli triggered the dome formation of epithelial cells2019

    • Author(s)
      Sumire Ishida-Ishihara, Masakazu Akiyama, Kazuya Furusawa, Isao Naguro, Hiroki Ryuno, Takamichi Sushida, Seiichiro Ishihara, Hisashi Haga
    • Organizer
      北海道大学ライフサイエンスフォーラム 2019
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] 広い細胞間隙が惹起するがん細胞の集団浸潤2019

    • Author(s)
      熊谷 祐二,小林 純子,石原 誠一郎,芳賀 永
    • Organizer
      第16回 日本病理学会カンファレンス
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] 浸透圧勾配が引き起こす上皮細胞シートのドーム形成2019

    • Author(s)
      石原(石田)すみれ、秋山正和、須志田隆道、古澤和也、名黒功、立野浩輝、石原誠一郎、芳賀永
    • Organizer
      日本生物物理学会北海道支部会例会
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] 浸透圧勾配が引き起こす上皮細胞シートのドーム形成2019

    • Author(s)
      石原(石田)すみれ、秋山正和、須志田隆道、古澤和也、名黒功、立野浩輝、石原誠一郎、芳賀永
    • Organizer
      日本生物物理学会北海道支部会例会
    • Data Source
      KAKENHI-INTERNATIONAL-15K21726
  • [Presentation] Collective Movement and 3D Morphology of Epithelial Cells on Viscoelastic Substrates2019

    • Author(s)
      芳賀 永
    • Organizer
      GSS International Symposium(invited speaker),札幌
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05856
  • [Presentation] 浸透圧勾配が引き起こす上皮細胞シートのドーム形成2019

    • Author(s)
      石原(石田)すみれ、秋山正和、須志田隆道、古澤和也、名黒功、立野浩輝、石原誠一郎、芳賀永
    • Organizer
      日本生物物理学会北海道支部会例会
    • Data Source
      KAKENHI-ORGANIZER-15H05856
  • [Presentation] Integrin-β1 promotes contact following in collective invasion of squamous carcinoma cells2019

    • Author(s)
      Yuji Kumagai, Junko Nio-Kobayashi, Seiichiro Ishihara, Hisashi Haga
    • Organizer
      第71回 日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] FSCN1 promotes breast cancer cell invasion via expression of LGR52019

    • Author(s)
      Yuki Ito, Seiichiro Ishihara, Masayuki Kano, Hisahiro Matsubara, Hisashi Haga
    • Organizer
      第71回 日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] Development of collagen gels with adjustable stiffness by genipin crosslinking2019

    • Author(s)
      Haruna Kurosawa, Seiichiro Ishihara, Hisashi Haga
    • Organizer
      7th International Life-Science Symposium
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] 細胞集団に自発的な3次元形態形成を促す培養技術の開発2018

    • Author(s)
      芳賀 永,古澤 和也
    • Organizer
      帝人21世紀フォーラム
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-15H05856
  • [Presentation] 細胞の集団運動と3次元形態形成2018

    • Author(s)
      芳賀 永
    • Organizer
      AIMaP研究会「反応拡散系と実験の融合」
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] ascin-1 promotes breast cancer cell invasion by regulating expression of LGR52018

    • Author(s)
      Yuki Ito, Seiichiro Ishihara, Hisashi Haga
    • Organizer
      第77回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] 多細胞系のメカノバイオロジー2018

    • Author(s)
      芳賀 永
    • Organizer
      CSJ化学フェスタ
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] 細胞集団に自発的な3次元形態形成を促す培養技術の開発2018

    • Author(s)
      芳賀 永,古澤 和也
    • Organizer
      帝人21世紀フォーラム
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] 細胞の集団運動と3次元形態形成2018

    • Author(s)
      芳賀 永
    • Organizer
      AIMaP研究会「反応拡散系と実験の融合」
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-15H05856
  • [Presentation] 細胞の基質牽引力と基質の粘弾性がもたらす上皮細胞の集団運動と3D形態形成2018

    • Author(s)
      芳賀 永
    • Organizer
      第95回日本生理学会大会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-15H05856
  • [Presentation] A mathematical model of collective cell migrations based on cell polarity2018

    • Author(s)
      Masakazu Akiyama,Takamaichi (Hokkaido University),Hitomi Mori(Hokkaido University),Sumire (Hokkaido University),Hisashi Haga(Hokkaido University)
    • Organizer
      11th European Conference on Mathematical and Theoretical Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21726
  • [Presentation] Intercellular ECM proteins promote collective invasion in human squamous carcinoma cells through the activation of intercellular integrin-β12018

    • Author(s)
      Yuji Kumagai, Junko Nio-Kobayashi, Seiichiro Ishihara, Hisashi Haga
    • Organizer
      第41回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] 多細胞系のメカノバイオロジー2018

    • Author(s)
      芳賀 永
    • Organizer
      CSJ化学フェスタ
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-15H05856
  • [Presentation] FSCN1-LGR5経路により誘導される乳がん細胞の浸潤機構2018

    • Author(s)
      伊東 祐紀, 石原 誠一郎, 芳賀 永
    • Organizer
      第41回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] 細胞の基質牽引力と基質の粘弾性がもたらす上皮細胞の集団運動と3D形態形成2018

    • Author(s)
      芳賀 永
    • Organizer
      第95回日本生理学会大会
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] Activation of intercellular integrin-β1 promotes collective invasion in human squamous carcinoma cells2018

    • Author(s)
      Yuji Kumagai, Seiichiro Ishihara, Hisashi Haga
    • Organizer
      第77回 日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] Collective Movement and 3D Morphogenesis of Epithelial Cells Responding to Viscoelastic Substrates2018

    • Author(s)
      Hisashi Haga
    • Organizer
      Japan-Toronto Morphogenesis Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] 多細胞系のメカノバイオロジー2018

    • Author(s)
      芳賀 永
    • Organizer
      CSJ化学フェスタ
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-15K21726
  • [Presentation] The role of intercellular gaps for collective invasion in cancer cell population2018

    • Author(s)
      Yuji Kumagai, Junko Nio-Kobayashi, Seiichiro Ishihara, Hisashi Haga
    • Organizer
      第70回 日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] A self-propelled particle model for representing collective cell migrations2018

    • Author(s)
      T. Sushida, H. Mori, S. Ishida, H.Haga, M. Akiyama
    • Organizer
      13th SIAM East Asian Section Conference 2018: June 22-25, 2018.
    • Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05856
  • [Presentation] Mechanosensitive Response of Cancer and Epithelial Cells Induced by in/on Viscoelastic Substrates2018

    • Author(s)
      芳賀 永
    • Organizer
      The 33rd Biomechanics Seminar
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] Epithelial cell polarity essential for collective migration and 3D morphogenesis of cell sheets2017

    • Author(s)
      Hisashi Haga
    • Organizer
      The 18th RIES-HOKUDAI International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05856
  • [Presentation] Collective movement and 3D morphogenesis of epithelial cells induced by viscoelasticity of the extracellular matrix2017

    • Author(s)
      Hisashi HAGA
    • Organizer
      Japan-UCI Meeting on 3D Morphogenesis
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] Substrate stiffness enhances cancer progression through transcription factor YAP and ATF52017

    • Author(s)
      Hisashi Haga
    • Organizer
      HU-KSMCB Joint Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] The role of integrin-α2β1 in the collective invasion of human A431 squamous carcinoma cells2017

    • Author(s)
      Yuji Kumagai, Junko Nio-Kobayashi, Hisashi Haga
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] The role of integrins in the collective invasion of human A431 squamous carcinoma cells2017

    • Author(s)
      Yuji Kumagai, Hisashi Haga
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] メカニカルなストレスによって促進されるがん細胞の悪性化2017

    • Author(s)
      芳賀 永
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] Epithelial cell polarity essential for collective migration and 3D morphogenesis of cell sheets2017

    • Author(s)
      芳賀 永
    • Organizer
      The 18th RIES-HOKUDAI International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] Investigation of the cell-cell adhesion mechanism of A431 cells with collective invasive potential2017

    • Author(s)
      Yuji Kumagai, Junko Nio-Kobayashi, Seiichiro Ishihara, Hisashi Haga
    • Organizer
      5th International Life-Science Symposium
    • Data Source
      KAKENHI-PROJECT-17K07150
  • [Presentation] 基底膜に覆われた細胞群の回転運動を表現するための数理モデル2017

    • Author(s)
      須志田隆道,森瞳,石田すみれ,古澤和也,芳賀永,秋山正和
    • Organizer
      2017年度応用数学合同研究集会
    • Data Source
      KAKENHI-ORGANIZER-15H05856
  • [Presentation] Role of ATF5 in cancer cell invasion of several diverse human cancer cell lines2016

    • Author(s)
      Akihiro Nukuda, Motoaki Yasuda, and Hisashi Haga
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Data Source
      KAKENHI-PROJECT-26430104
  • [Presentation] 細胞外基質の粘弾性に応答する上皮細胞の集団運動と3次元形態形成2016

    • Author(s)
      芳賀 永
    • Organizer
      第54回日本生物物理学会年会シンポジウム
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Invited
    • Data Source
      KAKENHI-INTERNATIONAL-15K21726
  • [Presentation] 細胞外基質の粘弾性に応答する上皮細胞の集団運動と3次元形態形成2016

    • Author(s)
      芳賀 永
    • Organizer
      第54回日本生物物理学会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-15H05856
  • [Presentation] Fascin-1 promotes cancer cell invasion via activation of Stat32016

    • Author(s)
      Toshiki Takahashi, Akihiro Nukuda, Masayuki Kano, Hisahiro Matsubara, and Hisashi Haga
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Data Source
      KAKENHI-PROJECT-26430104
  • [Presentation] 3D morphogensis of epithelial cells responding to viscoelasticity of the extracellular matrix2016

    • Author(s)
      Hisashi Haga
    • Organizer
      Japan-Austria joint meeting "Understanding the logic behind developmental dynamics
    • Place of Presentation
      IST, Klosterneuburg(Austria)
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] 転写因子ATF5による多様ながん細胞株の浸潤促進2016

    • Author(s)
      温田 晃弘, 安田 元昭, 水谷 武臣, 川端 和重, 芳賀 永
    • Organizer
      第68回日本細胞生物学会大会
    • Place of Presentation
      京都テルサ(京都府・京都市)
    • Data Source
      KAKENHI-PROJECT-26430104
  • [Presentation] 細胞外基質の粘弾性に応答する上皮細胞の集団運動と3次元形態形成2016

    • Author(s)
      芳賀 永
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場(茨城県・つくば市)
    • Invited
    • Data Source
      KAKENHI-PLANNED-15H05858
  • [Presentation] Activating transcription factor 5 promotes invasion of cancer cells via transcriptional activation of integrins2015

    • Author(s)
      Akihiro Nukuda, Seiichiro Ishihara, Motoaki Yasuda, and Hisashi Haga
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26430104
  • [Presentation] Activating transcription factor 5 promotes cancer cell invasion through transcriptional activation of integrins2015

    • Author(s)
      Akihiro Nukuda, Hiroki Endo, Seiichiro Ishihara, Motoaki Yasuda, Takeomi Mizutani, Kazushige Kawabata, and Hisashi Haga
    • Organizer
      2015 Annual Meeting of the American Society for Cell Biology
    • Place of Presentation
      サンディエゴ(アメリカ合衆国)
    • Year and Date
      2015-12-12
    • Data Source
      KAKENHI-PROJECT-26430104
  • [Presentation] 基質の硬さによって促進される大腸がん細胞の悪性化: 転写因子YAPを介した基質分解酵素MMP-7の発現亢進2015

    • Author(s)
      温田 晃弘, 石原 誠一郎, 水谷 武臣, 中村 公則, 綾部 時芳, 川端 和重, 芳賀 永
    • Organizer
      第67回日本細胞生物学会大会
    • Place of Presentation
      タワーホール船堀(東京都江戸川区)
    • Year and Date
      2015-06-30
    • Data Source
      KAKENHI-PROJECT-26430104
  • [Presentation] Collective migration of Madin-Darby canine kidney cells led by leader cells is dependent on Rac1,integrin beta1,and PI3K2014

    • Author(s)
      N.Yamaguchi, T.Mizutani, K.Kawabata, and H.Haga
    • Organizer
      第66回日本細胞生物学会大会
    • Place of Presentation
      奈良県新公会堂(奈良県春日野町)
    • Year and Date
      2014-06-11
    • Data Source
      KAKENHI-PUBLICLY-26106702
  • [Presentation] Epithelial sheet folding triggers a luminal structure of Madin-Darby canine kidney cells in a collagen gel2014

    • Author(s)
      S. Ishida, R. Tanaka, N. Yamaguchi, N. Ishikawa, G. Ogata, T. Mizutani, K. Kawabata, and H. Haga
    • Organizer
      International Symposium on 3D Tissue Fabrication
    • Place of Presentation
      東京大学生産技術研究(東京都)
    • Data Source
      KAKENHI-PUBLICLY-25127701
  • [Presentation] 3D tulip hat-like morphogenesis on deformable substrate induced by cellular contractile force2014

    • Author(s)
      M. Imai, T. Mizutani, K. Kawabata, and H. Haga
    • Organizer
      International Symposium on 3D Tissue Fabrication
    • Place of Presentation
      東京大学生産技術研究(東京都)
    • Data Source
      KAKENHI-PUBLICLY-25127701
  • [Presentation] Invasive migration of irradiation-survived human lung adenocarcinoma cells in 3D matrix2012

    • Author(s)
      芳賀永
    • Organizer
      第31回札幌国際がんシンポジウム
    • Place of Presentation
      北海道大学(札幌市)(招待講演)
    • Data Source
      KAKENHI-PROJECT-24370069
  • [Presentation] Integrin α2 dependent increased invasiveness of lung adenocarcinoma cells that survived 10 Gy ionizing radiation2012

    • Author(s)
      李 雪、石原 誠一郎、山田 泰士、安田 元昭、水谷 武臣、川端 和重、西岡 健、芳賀 永
    • Organizer
      第64回日本細胞生物学会大会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] EGFR and Integrin α2β1 Dependent Invasiveness of Lung Adenocarcinoma Cells that Survived 10 Gy Ionizing Radiation2012

    • Author(s)
      X. Li, S. Ishihara, M. Yasuda, T. Mizutani, K. Kawabata, T. Nishioka, H. Haga
    • Organizer
      第52回米国細胞生物学会年会
    • Place of Presentation
      モスコーンセンター(米国)
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Collective behavior of epithelial cells responding to stiffness, roughness and composition of extracellular matrix2012

    • Author(s)
      芳賀 永
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Involvement of cell polarity in folding phenomena of epithelial sheets2012

    • Author(s)
      石田すみれ、田中良昌、水谷武臣、川端和重、芳賀永
    • Organizer
      第64回日本細胞生物学会大会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Data Source
      KAKENHI-PROJECT-24370069
  • [Presentation] A stiff substrate activates transcription factor NF-B and increases the adhesion area in cancer cells2012

    • Author(s)
      石原 誠一郎、安田 元昭、芳賀 永
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      さっぽろ芸文館(北海道)
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Invasive migration of irradiation-survived human lung adenocarcinoma cells in 3D matrix2012

    • Author(s)
      芳賀 永
    • Organizer
      第31回札幌国際がんシンポジウム
    • Place of Presentation
      北海道大学(札幌市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Substrate stiffness enhances MMP-7 expression and ECM degradation in cancer cells2012

    • Author(s)
      佐々木 千絵、桝田 浩孝、中村 公則、綾部 時芳、水谷 武臣、川端 和重、芳賀 永
    • Organizer
      第64回日本細胞生物学会大会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Collective behavior of epithelial cells responding to stiffness, roughness and Composition of extracellular matrix2012

    • Author(s)
      芳賀永
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場(福岡市)(招待講演)
    • Data Source
      KAKENHI-PROJECT-24370069
  • [Presentation] Live cell imaging of collective migration in 3D morphogenesis of epithelial cells2012

    • Author(s)
      今井 美沙子、水谷 武臣、川端 和重、芳賀 永
    • Organizer
      第64回日本細胞生物学会大会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Live cell imaging of collective migration in 3D morphogenesis of epithelial cells2012

    • Author(s)
      今井美沙子、水谷武臣、川端和重、芳賀永
    • Organizer
      第64回日本細胞生物学会大会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Data Source
      KAKENHI-PROJECT-24370069
  • [Presentation] Invasive Migration ofIrradiation Survived Human LungAdenocarcinoma Cells in 3D Matrix2012

    • Author(s)
      芳賀永
    • Organizer
      第31回札幌国際がんシンポジウム(招待講演)
    • Place of Presentation
      北海道大学(札幌市)
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Involvement of cell polarity and cell migration in folding phenomena of epith elial sheets2012

    • Author(s)
      S. Ishida, R. Tanaka, N. Yamaguchi, T. Mizutani, K. Kawabata, H. Haga
    • Organizer
      第52回米国細胞生物学会年会
    • Place of Presentation
      モスコーンセンター(米国,サンフランシスコ)
    • Data Source
      KAKENHI-PROJECT-24370069
  • [Presentation] Involvement of cell polarity in folding phenomena of epithelial sheets2012

    • Author(s)
      石田 すみれ、田中 良昌、水谷 武臣、川端 和重、芳賀 永
    • Organizer
      第64回日本細胞生物学会大会
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Involvement of cell polarity and cell migration in folding phenomena of epithelial sheets2012

    • Author(s)
      S. Ishida, R. Tanaka, N. Yamaguchi, T. Mizutani, K. Kawabata, H. Haga
    • Organizer
      第52回米国細胞生物学会年会
    • Place of Presentation
      モスコーンセンター(米国)
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] 軟らかい基質がもたらす上皮細胞集団の協調運動2011

    • Author(s)
      芳賀永
    • Organizer
      日本動物学会第82回大会
    • Place of Presentation
      旭川市大雪クリスタルホール(北海道)(招待講演)
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] 細胞外基質の硬さ・表面形状・組成に応答する上皮細胞の集団協調運動2011

    • Author(s)
      芳賀永
    • Organizer
      口腔先端応用医科学研究会第3回学術会議
    • Place of Presentation
      東京医科歯科大(東京都) 招待講演
    • Year and Date
      2011-01-22
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] 細胞外基質の硬さ・表面形状・組成に応答する上皮細胞の集団協調運動2011

    • Author(s)
      芳賀永
    • Organizer
      口腔先端応用医科学研究会第3回学術会議
    • Place of Presentation
      東京医科歯科大(東京都) 招待講演
    • Year and Date
      2011-01-22
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] 軟らかい基質がもたらす上皮細胞集団の協調運動2011

    • Author(s)
      芳賀永
    • Organizer
      日本動物学会第82回大会
    • Place of Presentation
      旭川市大雪クリスタルホール
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] Collective behavior of epithelial cells responding to stiffness of the extracellular matrix2011

    • Author(s)
      芳賀永
    • Organizer
      第63回日本細胞生物学会大会
    • Place of Presentation
      北海道大学
    • Year and Date
      2011-06-27
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] 細胞外基質の硬さ・表面形状・組成に応答する上皮細胞の集団協調運動2011

    • Author(s)
      芳賀永
    • Organizer
      口腔先端応用医科学研究会第3回学術会議
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2011-01-22
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] 軟らかい基質がもたらす上皮細胞集団の協調運動2011

    • Author(s)
      芳賀永
    • Organizer
      日本動物学会第82回大会
    • Place of Presentation
      旭川市大雪クリスタルホール(北海道)(招待講演)
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] Substrate stiffness regulates NF-k B expression and malignancy in cancer cells2011

    • Author(s)
      石原誠一郎、安田元昭、水谷武臣、川端和重、芳賀永
    • Organizer
      第63回日本細胞生物学会大会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2011-06-27
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] NF-k B expression in cancer cells regulated by substrate stiffness2011

    • Author(s)
      石原誠一郎、安田元昭、水谷武臣、川端和重、芳賀永
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Collective behavior of epithelial cells responding to stiffness of the extracellular matrix2011

    • Author(s)
      芳賀永
    • Organizer
      第63回日本細胞生物学会大会
    • Place of Presentation
      北海道大学(札幌市)(招待講演)
    • Year and Date
      2011-06-27
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Substrate stiffness regulates NF-k B expression and activity in cancer cells2011

    • Author(s)
      S.Ishihara, M.Yasuda, T.Mizutani, K.Kawabata, H.Haga
    • Organizer
      第51回米国細胞生物学会年会
    • Place of Presentation
      Colorado Convention Center (USA)
    • Year and Date
      2011-12-03
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Collective behavior of epithelial cells responding to stiffness of the extracellular matrix2011

    • Author(s)
      芳賀永
    • Organizer
      第63回日本細胞生物学会大会
    • Place of Presentation
      北海道大学(札幌市)(招待講演)
    • Year and Date
      2011-06-27
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] 3次元培養環境においてみられる放射線照射後に生残した肺がん細胞の浸潤機構2010

    • Author(s)
      石原誠一郎、安田元昭、武島嗣英、水谷武臣、川端和重、西岡健、芳賀永
    • Organizer
      第62回日本細胞生物学会大会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2010-05-19
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Integrin Dependent Invasive Mmigration in 3D Collagen Matrix of Human Lung Adenocarcinoma Cells that Survived 10Gy Iirradiation2010

    • Author(s)
      S.Ishihara, M.Yasuda, T.Takeshima, T.Mizutani, K.Kawabata, T.Nishioka, H.Haga
    • Organizer
      札幌国際がんシンポジウム2010
    • Place of Presentation
      北海道大学(札幌)
    • Year and Date
      2010-06-28
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] 培養基質の硬さがもたらす細胞集団の協調運動と形態形成2010

    • Author(s)
      芳賀永
    • Organizer
      第1回バイオエンジニアリングサマースクール
    • Place of Presentation
      北海道医療大学・サテライトキャンパス
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] 細胞外基質の硬さおよび組成に応答する細胞集団の協調挙動と形態形成2010

    • Author(s)
      芳賀永
    • Organizer
      北海道医療大学個体差研セミナー
    • Place of Presentation
      北海道医療大学(当別町) 招待講演
    • Year and Date
      2010-04-02
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] 細胞外基質の硬さおよび組成に応答する細胞集団の協調挙動と形態形成2010

    • Author(s)
      芳賀永
    • Organizer
      北海道医療大学個体差研セミナー
    • Place of Presentation
      北海道医療大学(石狩) 招待講演
    • Year and Date
      2010-04-02
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] 培養基質の硬さがもたらす細胞集団の協調運動と形態形成2010

    • Author(s)
      芳賀永
    • Organizer
      第1回バイオエンジニアリングサマースクールin Sapporo
    • Place of Presentation
      北海道医療大学サテライトキャンパス(石狩) 招待講演
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] 上皮細胞の集団運動と3次元形態形成2010

    • Author(s)
      芳賀永
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] 培養基質の硬さがもたらす細胞集団の協調運動と形態形成2010

    • Author(s)
      芳賀永
    • Organizer
      第1回バイオエンジニアリングサマースクールin Sapporo
    • Place of Presentation
      北海道医療大学・サテライトキャンパス(札幌市) 招待講演
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] 細胞外基質の硬さおよび組成に応答する細胞集団の協調挙動と形態形成2010

    • Author(s)
      芳賀永
    • Organizer
      北海道医療大学個体差研セミナー
    • Place of Presentation
      北海道医療大学
    • Year and Date
      2010-04-02
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] Enhancement of NE- EIB Expression and Malignancy of Cancer Cells Induced by Substrate Stiffness2010

    • Author(s)
      S.Ishihara, M.Yasuda, T.Mizutani, K.Kawabata, H.Haga
    • Organizer
      第50回米国細胞生物学会年会
    • Place of Presentation
      Pennsylvania Convention Center(アメリカ)
    • Year and Date
      2010-12-13
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] Invasive Mechanism of Lung Adenocarcinoma Cells Revealed by 3D Collagen Culture2010

    • Author(s)
      S.Ishihara, M.Yasuda, T.Takeshima, T.Mizutani, K.Kawabata, T.Nishioka, H.Haga
    • Organizer
      第57回マトリックス研究会大会
    • Place of Presentation
      秋田拠点センター・アルヴェ(秋田)
    • Year and Date
      2010-08-19
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] 上皮細胞の集団運動と3次元形態形成2010

    • Author(s)
      芳賀永
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場(神戸) 招待講演
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] 基質の硬さがもたらす転写因子NF-κBの発現2010

    • Author(s)
      石原誠一郎、安田元昭、水谷武臣、川端和重、芳賀永
    • Organizer
      第5回メカノセンシング研究会
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2010-11-26
    • Data Source
      KAKENHI-PROJECT-21249065
  • [Presentation] 上皮細胞の集団運動と3次元形態形成2010

    • Author(s)
      芳賀永
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場(神戸市) 招待講演
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] 3D Morphogenesis and Collective Migration of Epithelial Cells Observed on a Soft Substrate Containing Laminin2009

    • Author(s)
      芳賀永
    • Organizer
      第49回米国細胞生物学会年会
    • Place of Presentation
      サンディエゴコンベンションセンター
    • Year and Date
      2009-12-08
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] 3D Morphogenesis and Collective Migration of Epithelial Cells Observed on a Soft Substrate Containing Laminin2009

    • Author(s)
      H.Haga, et al.
    • Organizer
      第49回米国細胞生物学会年会
    • Place of Presentation
      米国・サンディエゴ市・コンベンションセンター
    • Year and Date
      2009-12-08
    • Data Source
      KAKENHI-PROJECT-21570158
  • [Presentation] 細胞系における協調運動に伴う局所弾性率の時空間測定2007

    • Author(s)
      芳賀 永
    • Organizer
      日本表面科学会 第27回表面科学講演大会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-01
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Presentation] 細胞系における協調運動に伴う局所弾性率の時空間測定2007

    • Author(s)
      芳賀永
    • Organizer
      日本表面科学会第27回表面科学講演大会招待講演
    • Place of Presentation
      東京都
    • Year and Date
      2007-11-01
    • Data Source
      KAKENHI-PROJECT-18340122
  • [Presentation] Invasive ability is regulated by activating transcription factor 5 in high invasive cancer cells

    • Author(s)
      H. Endoh, S. Ishihara, T. Nishioka, M. Yasuda, and H. Haga
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26430104
  • [Presentation] Activating transcription factor 5 enhances radioresistance and malignant phenotypes in lung cancer cells

    • Author(s)
      S. Ishihara, M. Yasuda, T. Nishioka, and H. Haga
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26430104
  • [Presentation] Collective migration of Madin-Darby canine kidney cells led by leader cells is dependent on Rac1, integrin beta1, and PI3K

    • Author(s)
      N. Yamaguchi, T. Mizutani, K. Kawabata, and H.i Haga
    • Organizer
      第66回日本細胞生物学会大会
    • Place of Presentation
      奈良県新公会堂(奈良県春日野町)
    • Year and Date
      2014-06-11 – 2014-06-13
    • Data Source
      KAKENHI-PUBLICLY-25127701
  • [Presentation] Substrate stiffness enhances expression of matrix metalloproteinase 7 via myosin phosphorylation in colon cancer cells

    • Author(s)
      A. Nukuda, S. Ishihara, K. Nakamura, T. Ayabe, and H. Haga
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26430104
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    # of Collaborated Products: 1 results
  • 52.  KHIN KHIN Tha (20451445)
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  • 53.  NAM Jin-min (60414132)
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    # of Collaborated Products: 0 results
  • 54.  SABE Hisataka (40187282)
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    # of Collaborated Products: 0 results
  • 55.  INUBUSHI Masayuki (70399830)
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  • 56.  SHINAGAWA Naofumi (20431372)
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  • 57.  KENNETH Sutherland (30451446)
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  • 58.  UYEDA Taro (90356551)
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  • 59.  YUMURA Shigehiko (70183986)
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  • 60.  NOGUCHI Taro (90615866)
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  • 61.  ADACHI Taiji (40243323)
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  • 62.  HIRAI Yoshihiko (50285300)
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  • 63.  KAWATA Hiroaki (90186099)
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  • 64.  KIKUTA Hisao (10214743)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 65.  TANAKA Yoshio (60081246)
    # of Collaborated Projects: 1 results
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  • 66.  田中 勲 (70093052)
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  • 67.  武島 嗣英 (10360950)
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  • 68.  古澤 和也 (00510017)
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  • 69.  泉 健次 (80242436)
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  • 70.  加来 賢 (30547542)
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  • 71.  佐藤 大祐 (70778703)
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  • 72.  凌 一葦 (70804540)
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  • 73.  鈴木 絢子 (70869916)
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  • 74.  YOSHIZAWA Shin
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  • 75.  YOKOTA Hideo
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  • 76.  SAKANE Ayuko
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  • 77.  SUSHIDA Takamichi
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  • 78.  YAMADA tamaki
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  • 79.  NISHIDE Shinya
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  • 80.  Fujioka Mari
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  • 81.  Horiuchi Kosui
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  • 82.  Satoh Aya O.
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  • 83.  SUZUKI Kentaro
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  • 84.  MIYAGAWA Shinichi
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  • 85.  HINO Shinjiro
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  • 86.  HINO Yuko
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  • 87.  KUROKAWA Takayuki
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  • 88.  NAKANISHI Kazuaki
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    # of Collaborated Products: 1 results
  • 89.  KAMIYAMA Toshiya
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  • 90.  YOKOO Hideki
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    # of Collaborated Products: 1 results
  • 91.  ENOMOTO Atsushi
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  • 92.  水谷 武臣
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    # of Collaborated Products: 16 results
  • 93.  中村 公則
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  • 94.  出口 真次
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    # of Collaborated Products: 1 results
  • 95.  斎藤 博幸
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    # of Collaborated Products: 1 results
  • 96.  佐々木 卓也
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    # of Collaborated Products: 1 results
  • 97.  南保 明日香
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    # of Collaborated Products: 1 results
  • 98.  津田 真寿美
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    # of Collaborated Products: 2 results
  • 99.  大場 雄介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 100.  藤岡 容一朗
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    # of Collaborated Products: 1 results
  • 101.  中尾 光善
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    # of Collaborated Products: 1 results
  • 102.  山田 源
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    # of Collaborated Products: 1 results
  • 103.  嶋村 健児
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 104.  田中 伸哉
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    # of Collaborated Products: 1 results
  • 105.  ぐん 剣萍
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 106.  高橋 正行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 107.  大友 康平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 108.  根本 知己
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 109.  中垣 俊之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 110.  青木 茂樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 111.  浅井 直也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 112.  高橋 雅英
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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