HAGA Hisashi 芳賀永

Researcher Number	00292045
Other IDs
Affiliation *help	2015 – 2017 : 北海道大学, 先端生命科学研究院, 教授 2013 – 2016 : 北海道大学, 先端生命科学研究科(研究院), 教授 2014 : 北海道大学, 先端生命科学研究科, 教授 2014 : 北海道大学, 大学院先端生命科学研究院, 教授 2011 – 2013 : Hokkaido University, 先端生命科学研究科(研究院), 准教授 … More
Review Section/Research Field	Principal Investigator Tumor biology / Biological Sciences / Cell biology / Science and Engineering / Biophysics Except Principal Investigator Radiation science / Biological Sciences / Dynamics/Control / Biophysics / Biophysics/Chemical physics / Bioinformatics/Life informatics / Structural biochemistry
Keywords	Principal Investigator 細胞・組織 / 集団運動 / コラーゲンゲル / がん細胞 / メカノセンス / 上皮細胞 / ゲル基質 / 上皮細胞シート / 細胞運動 / 転写調節因子 … More Except Principal Investigator 細胞 / 放射線治療 / ３次元 / apoptosis / irradiation / ミオシン / 放射線生物学 / 走査型プローブ顕微鏡 / p53 / 細胞運動 / 形態形成 / 数理モデル / 発生 / ATF5 / 細胞コロニー / 細胞遊走 / visco-eleastic / 細胞極性 / 粘弾性 / メカノバイオロジー / システムバイオロジー / メカノセンシティビティ / 数理 / p16 / atomic force microscopy / ３Ｄ / 蛍光プローブ / 力学 / アクチン / 動体追跡 / MDシミュレーション / システム / 低酸素 / 表面剛性 / cell movement / 電子線トラック解析 / cell / ホメオスタシス / AFM / 転写因子 / メカノセンサー / HIF1-alpha / living material / 放射線感受性 / 表面粘性 / 形態 / TGFB-1 / 生体の動き / HIF/alpha / 医学研究 / 工学 / 力学的メモリー効果 / 低酸素細胞 / フォースモジュレーション法 / HIF-1a / mitosis / X線結晶解析 / repopulation / タンパク質結晶化 / 非線形最適化 / シミュレーション / リン酸化 / 物理計測 / 計算科学 / 細胞形態 / translation / trascription / MMP / cancer stem cell / 物理測定 / ３Ｄ形態 / モンテカルロ法 / プラスチック檢出器 / radiation / HIF / radiosensitivity / transcription factor / 胃癌 / 生体 / UTR / 体幹部定位放射線照射 / プラスチック検出器 / 量子線シミュレーション / バーチャル研究所 / 構造多型性 / 放射線 / 力学平衡 / 力学的応答 / Radiotherapy / カンチレバー Less

がん細胞に集団浸潤を誘引する接触追従の機序解明と普遍性の検証Principal InvestigatorOngoing
- Principal Investigator
  
  芳賀永
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Hokkaido University
3D morphologicOngoing
- Principal Investigator
  
  近藤滋
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
３Ｄ形態ロジックの国際共同研究を加速するバーチャル研究所Ongoing
- Principal Investigator
  
  近藤滋
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
インビトロ系における細胞シートからの３Ｄ形態形成Principal InvestigatorOngoing
- Principal Investigator
  
  芳賀永
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Stiff Substrates Enhances ATF5-Signaling-Mediated Invasive Ability in Cancer CellsPrincipal Investigator
- Principal Investigator
  
  HAGA HISASHI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Hokkaido University
ゲル基質の軟らかさと粘性を利用した上皮シートの3次元組織構築Principal Investigator
- Principal Investigator
  
  芳賀永
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
多数の細胞の力と運動がもたらす管腔構造形成のロジックPrincipal Investigator
- Principal Investigator
  
  芳賀永
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Tension-induced conformational changes of actin filaments and their influence on actin binding and intracellular localization of myosin.
- Principal Investigator
  
  UYEDA Taro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  National Institute of Advanced Industrial Science and Technology
がん細胞は自身の生存をかけ放射線域を逃れるべく上皮間葉移行をなしうるか
- Principal Investigator
  
  西岡健
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Research for Real-time Tracking Medical Science
- Principal Investigator
  
  SHIRATO Hiroki
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Collective migration of epithelial cells induced by softness of substratesPrincipal Investigator
- Principal Investigator
  
  HAGA Hisashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Hokkaido University
力学的応答測定を利用した極微小タンパク質結晶の判別・評価法の開発
- Principal Investigator
  
  田中勲
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Hokkaido University
The secret of radiation-surviving cell : multidisciplinary approach to eradicate cancer
- Principal Investigator
  
  NISHIOKA Takeshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
Mechanical memory effect of cells in colony
- Principal Investigator
  
  KAWABATA Kazushige
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics/Chemical physics
- Research Institution
  Hokkaido University
Radiation-induced highly-malignant cancer cells: the mechanism and how to deal with it
- Principal Investigator
  
  NISHIOKA Takeshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hokkaido University
細胞システムにおける「力学平衡」モデルの実証
- Principal Investigator
  
  KAWABATA Kazushige
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bioinformatics/Life informatics
- Research Institution
  Hokkaido University
ナノ力学プローブ顕微鏡による結合組織の形成過程における力学的制御機構の解明Principal Investigator
- Principal Investigator
  
  芳賀永
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Hokkaido University
Quantitative evaluation of visco-elastic distribution of living cells using scanning probe microscopy
- Principal Investigator
  
  HIRAI Yoshihiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dynamics/Control
- Research Institution
  Osaka Prefecture University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] Chromosome Nanoscience and Technology2007
- Author(s)
  K. Kawabata, K. Nomura, K. Ikeda. O. Hoshi, D. Fukushi, H. Haga and T. Ushiki
- Publisher
  Taylor & Francis Group
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Role of ATF5 in the invasive potential of diverse human cancer cell lines2016
- Author(s)
  Akihiro Nukuda, Hiroki Endoh, Motoaki Yasuda, Takeomi Mizutani, Kazushige Kawabata, Hisashi Haga
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume : 474 Issue : 3 Pages : 509-514
- Publisher
  Elsevier
- Year and Date
  2016-06-03
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25287106, KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-15K15010
[Journal Article] Data set for comparison of cellular dynamics between human AAVS1 locus-modified and wild-type cells2016
- Author(s)
  Takeomi Mizutani, Hisashi Haga, Kazushige Kawabata
- Journal Title
  
  Data in Brief
  
  Volume : 6 Pages : 793-798
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15010, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-25287106, KAKENHI-PLANNED-15H05858, KAKENHI-PROJECT-26430104, KAKENHI-INTERNATIONAL-15K21726
[Journal Article] An improved method for western blotting when extracting proteins from mammalian cells cultured on a collagen gel under serum-free conditions2016
- Author(s)
  S. Ishihara, M. Yasuda, A. Ishizu, M. Ishikawa, H. Shirato, H. Haga
- Journal Title
  
  Cytotechnology
  
  Volume : 68 Issue : 1 Pages : 25-32
- Publisher
  Springer
- PMID
  info:pmid/25005915
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390285, KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106, KAKENHI-PROJECT-26430104
[Journal Article] Conformational Plasticity of JRAB/MICAL-L2 Provides 'Law and Order'2016
- Author(s)
  A. Sakane, S. Yoshizawa, M. Nishimura, Y. Tsuchiya, N. Matsushita, K. Miyake, K. Horikawa, I. Imoto, C. Mizuguchi, H. Saito, T. Ueno, S. Matsushita, H. Haga, S. Deguchi, K. Mizuguchi, H.
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume : 27 Pages : 3095-3108
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-15H05858, KAKENHI-PLANNED-15H05954, KAKENHI-PROJECT-15H03004, KAKENHI-PROJECT-16J01828, KAKENHI-PROJECT-25293006, KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-26460370, KAKENHI-PROJECT-15K15084, KAKENHI-PROJECT-16K12872, KAKENHI-INTERNATIONAL-15K21726
[Journal Article] Receptor activator of NF-κB ligand induces cell adhesion and integrin α2 expression via NF-κB in head and neck cancers2016
- Author(s)
  T.Yamada, M. Tsuda, T. Wagatsuma, Y. Fujioka, M. Fujioka, A. O. Satoh, K. Horiuchi, S. Nishide, A. Nanbo, Y. Totsuka, H. Haga, S. Tanaka, M. Shindoh, and Y. Ohba
- Journal Title
  
  Scientific reports
  
  Volume : 6 Pages : 23545
- Publisher
  Nature Publishing Group
- Year and Date
  2016-03-24
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-26460545, KAKENHI-PROJECT-15K15106, KAKENHI-PUBLICLY-26115701, KAKENHI-PROJECT-26670414, KAKENHI-PROJECT-26860254, KAKENHI-PROJECT-26861539, KAKENHI-PUBLICLY-15H01248, KAKENHI-PROJECT-26293041, KAKENHI-PROJECT-15K15023, KAKENHI-PROJECT-15KK0290
[Journal Article] Three-dimensional morphogenesis of MDCK cells induced by cellular contractile forces on a viscous substrate2015
- Author(s)
  Misako Imai, Kazuya Furusawa, Takeomi Mizutani, Kazushige Kawabata, Hisashi Haga
- Journal Title
  
  Scientific reports
  
  Volume : 5 Pages : 14208
- Publisher
  Nature Publishing Group
- Year and Date
  2015-09-16
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15010, KAKENHI-PROJECT-15K16330, KAKENHI-PLANNED-15H05858, KAKENHI-PUBLICLY-26106703, KAKENHI-PROJECT-25287106, KAKENHI-PUBLICLY-26106702, KAKENHI-ORGANIZER-15H05856
[Journal Article] Transgene integration into the human AAVS1 locus enhances myosin II-dependent contractile force by reducing expression of myosin binding subunit 852015
- Author(s)
  T. Mizutani, R. Li, H. Haga, and K. Kawabata
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume : 465 Issue : 2 Pages : 270-274
- Publisher
  Elsevier
- PMID
  info:pmid/26260320
- Year and Date
  2015-09-18
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-15K15010, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-25287106, KAKENHI-PUBLICLY-26106702, KAKENHI-ORGANIZER-15H05856
[Journal Article] Activating Transcription Factor 5 Enhances Radioresistance and Malignancy in Cancer Cells2015
- Author(s)
  S. Ishihara, M. Yasuda, A. Ishizu, M. Ishikawa, H. Shirato, and H. Haga
- Journal Title
  
  Oncotarget
  
  Volume : 6 Pages : 4602-4614
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26430104
[Journal Article] Filamin B Enhances the Invasiveness of Cancer Cells into 3D Collagen Matrices2015
- Author(s)
  Y. Iguchi, S. Ishihara, Y. Uchida, K. Tajima, T. Mizutani, K. Kawabata, and H. Haga
- Journal Title
  
  Cell Structure and Function
  
  Volume : 40 Pages : 61-67
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26430104
[Journal Article] Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin beta 1 and PI3K2015
- Author(s)
  N. Yamaguchi, T. Mizutani, K. Kawabata, and H. Haga
- Journal Title
  
  Scientific reports
  
  Volume : 5 Pages : 7656
- Publisher
  Nature Publishing Group
- Year and Date
  2015-01-07
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25127701, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-26430104, KAKENHI-PUBLICLY-26106702
[Journal Article] Stiff substrates increase YAP-signaling-mediated matrix metalloproteinase-7 expression2015
- Author(s)
  A. Nukuda, C. Sasaki, S. Ishihara, T. Mizutani, K. Nakamura, T. Ayabe, K. Kawabata, and H. Haga
- Journal Title
  
  Oncogenesis
  
  Volume : 4 Pages : e165
- Publisher
  Nature Publishing Group
- PMID
  info:pmid/26344692
- Year and Date
  2015-09-07
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26430104, KAKENHI-PROJECT-26462831, KAKENHI-PROJECT-25287106
[Journal Article] Compressive Stress Induces Dephosphorylation of the Myosin Regulatory Light Chain via RhoA Phosphorylation by the Adenylyl Cyclase/Protein Kinase A Signaling Pathway2015
- Author(s)
  Takemoto, T., Ishihara, S., Mizutani, T., Kawabata, K., Haga, H.
- Journal Title
  
  PLOS ONE
  
  Volume : 10 Issue : 3 Pages : e0117937
- Publisher
  PUBLIC LIBRARY SCIENCE
- PMID
  info:pmid/25734240
- Year and Date
  2015-03-03
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-25127701, KAKENHI-PUBLICLY-26106704, KAKENHI-PROJECT-26430104, KAKENHI-PUBLICLY-26106702
[Journal Article] Modulation of extracellular conditions prevents the multilayering of the simple epithelium2014
- Author(s)
  T. Mizutani, K. Takeda, H. Haga, M. Todo, K. Kawabata
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume : Vol. 141(5) Pages : 459-471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770167, KAKENHI-PUBLICLY-24106502, KAKENHI-PROJECT-24370069, KAKENHI-PROJECT-25287106
[Journal Article] Epithelial Sheet Folding Induces Lumen Formation by Madin-Darby Canine Kidney Cells in a Collagen Gel2014
- Author(s)
  S. Ishida, R. Tanaka, N. Yamaguchi, G. Ogata, T. Mizutani, K. Kawabata, and H. Haga
- Journal Title
  
  PLOS ONE
  
  Volume : 9 Issue : 8 Pages : e99655
- Publisher
  Public Library of Science
- Year and Date
  2014-08-29
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106, KAKENHI-PUBLICLY-26106702
[Journal Article] An Improved Method for Western Blotting When Extracting Proteins from Mammalian Cells Cultured on a Collagen Gel under Serum-free Conditions2014
- Author(s)
  S.Ishihara, T.Mizutani, K.Kawabata, and H.Haga
- Journal Title
  
  Cytotechnology
  
  Volume : 09 Jul. Pages : 1-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-26106702
[Journal Article] Coating extracelular matrix proteins on a (3-aminopropyl)triethoxysilane-treated glass substrate for improved cell culture.2014
- Author(s)
  Masuda, H.T., Ishihara, S., Harada, I., Mizutani, T., Ishikawa, M., Kawabata, K., Haga, H..
- Journal Title
  
  Biotechniques
  
  Volume : 56 Pages : 172-179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106
[Journal Article] Irradiation-tolerant Lung Cancer Cells Acquire Invasive Ability Dependent on Dephosphorylation of the Myosin Regulatory Light Chain2013
- Author(s)
  S. Ishihara, M. Yasuda, T. Nishioka, T. Mizutani, K. Kawabata, H. Shirato and H. Haga
- Journal Title
  
  FEBS Letters
  
  Volume : 587 Pages : 732-736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Substrate stiffness regulates temporary NF-kappa B activation via actomyosin contractions2013
- Author(s)
  Seiichiro Ishihara, Motoaki Yasuda, Ichiro Harada, Takeomi Mizutani, Kazushige Kawabata, Hisashi Haga
- Journal Title
  
  Experimental cell research
  
  Volume : 319 Issue : 19 Pages : 2916-2927
- Publisher
  Elsevier inc
- Year and Date
  2013-11-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770167, KAKENHI-PUBLICLY-24106502, KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-25127701, KAKENHI-PROJECT-25287106
[Journal Article] Lung Cancer Cells That Survive Ionizing Radiation Show Increased Integrin alpha 2 beta 1-and EGFR-Dependent Invasiveness2013
- Author(s)
  Xue Li, Seiichiro Ishihara, Motoaki Yasuda, Takeshi Nishioka, Takeomi Mizutani, Masayori Ishikawa, Kazushige Kawabata, Hiroki Shirato, Hisashi Haga
- Journal Title
  
  Plos one
  
  Volume : 8 Issue : 8 Pages : 1-12
- Publisher
  Public library science
- Year and Date
  2013-08-08
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770167, KAKENHI-PUBLICLY-24106502, KAKENHI-PROJECT-24390285, KAKENHI-PROJECT-25287106
[Journal Article] Irradiation-tolerant lung cancer cells acquire invasive ability dependent on dephosphorylation of the myosin regulatory light chain2013
- Author(s)
  Ishihara S, Yasuda M, Nishioka T, Mizutani T, Kawabata K, Shirato H, Haga H
- Journal Title
  
  FEBS Letters
  
  Volume : 587 Issue : 6 Pages : 732-736
- Publisher
  Elsevier
- Year and Date
  2013-03-18
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-23651099, KAKENHI-PROJECT-23770167, KAKENHI-PROJECT-24370069, KAKENHI-PROJECT-24390285
[Journal Article] Tempo-Spatial Change of Cellular Stiffness and Geometry in the Process of Developing Epithelial Cell-Cell Adhesion Measured by Atomic Force Microscopy2013
- Author(s)
  R. Tanaka, T. Mizutani, H. Haga, and K. Kawabata
- Journal Title
  
  pn. J. Appl. Phys. Conf. Proc.
  
  Volume : 1 Pages : 11004-11004
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25127701
[Journal Article] Neuronal correlates of multiple top-down signals during covert tracking of moving objects in macaque prefrontal cortex2012
- Author(s)
  Matsushima, A. & Tanaka, M.
- Journal Title
  
  J. Cogn. Neurosci
  
  Volume : 24 Pages : 2043-2056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-23651099, KAKENHI-PROJECT-23770167, KAKENHI-PROJECT-24370069, KAKENHI-PUBLICLY-24106502
[Journal Article] Relationship between Diffusion-Weighted　Magnetic　Resonance Imaging and Histological Tumor Grading of Hepatocellular Carcinoma2012
- Author(s)
  Nakanishi M, Chuma M, Hige S, Omatsu T, Yokoo H, Nakanishi K, Kamiyama T, Kubota K, Haga H, Matsuno Y, Onodera Y, Kato M, Asaka M.
- Journal Title
  
  Ann Surg Oncol
  
  Volume : 19 Pages : 1302-1309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-21390369
[Journal Article] Active fluctuation in the cortical cytoskeleton observed by high-speed live-cell scanning probe microscopy2011
- Author(s)
  K.Tamura, T.Mizutani, H.Haga, K.Kawabata
- Journal Title
  
  Acta Biomater.
  
  Volume : 7 Pages : 3766-3772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065, KAKENHI-PROJECT-21570158, KAKENHI-PROJECT-23651099, KAKENHI-PROJECT-23770167
[Journal Article] Radiation-induced cancer cell repopulation : a possible mechanism implied by experiments using transplantable mouse-derived sarcoma cell line.2011
- Author(s)
  Nishioka T, Yasuda M, Takeshima T, Haga H, Miyai Y, Shibata K, Yamazaki R, Shirato H, Teduka M, Date H.
- Journal Title
  
  Cell Struct Funct. 36
  
  Pages : 13-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390319
[Journal Article] Radiation-induced Cancer Cell Repopulation : A possible mechanism implied by experiments using trasplantable mouse-derived sarcoma cell line2011
- Author(s)
  T.Nishioka, M.Yasuda, T.Takeshima, H.Haga, Y.Miyai, K.Shibata, H.Shirato, M, Teduka, H.Date.
- Journal Title
  
  Cell Structure and Function
  
  Volume : 36 Pages : 13-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Integrin betal-dependent invasive migration of irradiation-tolerant human lung adenocarcinoma cells in 3D collagen matrix.2010
- Author(s)
  Ishihara S, Haga H, Yasuda M, Mizutani T, Kawabata K, Shirato H, Nishioka T.
- Journal Title
  
  Biochem Biophys Res. 396
  
  Pages : 651-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390319
[Journal Article] Nano-mechanical Properties of Living Cells Expressing Constitutively Active RhoA Effectors2010
- Author(s)
  K. Tamura, T. Mizutani, H. Haga, and K. Kawabata
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume : 403巻 Pages : 363-367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570158
[Journal Article] Integrin β1-dependent Invasive Migration of Irradiation-tolerant Human Lung Adenocarcinoma Cells in 3D Collagen Matrix2010
- Author(s)
  S.Ishihara, H.Haga, M.Yasuda, T.Mizutani, K.Kawabata, H.Shirato, T.Nishioka
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume : 396 Pages : 651-655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249065
[Journal Article] Mechanical Response of Sinle Myoblasts to Various Stretching Patterns Visualized by Scanning Proe Microscoy2009
- Author(s)
  W. Mitsui, K. Tamura, T. Mizutani,Haga and K. Kawabata
- Journal Title
  
  Archivesof Histology and Cytology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Novel Function of Transcripion Factor ATF5 : Blockade of p53-dependent Apoptosis Induced by Ionizing Irradation2009
- Author(s)
  T. Ni shioka, Y. Miyai, H. Haga, K. Kawabata, H. Shirato, A. Homma, K. Shibata and M. Yasuda
- Journal Title
  
  Cell Structre and Function 34
  
  Pages : 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Regulation of Cellular Contractile Force in Response t Mechanical Stretch by Diphosphorylation of Myosin Regulatory Light Chain via RhoA Signaling Cascade2009
- Author(s)
  T. Mizutani, K.Kawabata, Y. Koyama, M. Takahashi, H. Haga
- Journal Title
  
  Cell Motility and the Cytoskeleton (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Superselective high-dose cisplatin infusion with concomitant radiotherapy in patients with advanced cancer of the nasal cavity and paranasal sinuses : a single institution experience.2009
- Author(s)
  Tsutsumi K, Tsuda M, Yazawa N, Nakamura H, Ishihara S, Haga H, Yasuda M, Yamazaki R, Shirato H, Kawaguchi H, Nishioka T
- Journal Title
  
  Cell Structure and Function 34
  
  Pages : 86-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390319
[Journal Article] Nishioka T, Miyai Y, Haga H, Kawabata K, Shirato H, Homma A, Shibata K, and Yasuda M2009
- Author(s)
  Nishioka T, Miyai Y, Haga H
- Journal Title
  
  Cell Struct Funct 34
  
  Pages : 17-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390319
[Journal Article] Regulation of Cellular Contractile Force in Response to Mechanical Stretch by Diphosphorylation of Myosin Regulatory Light Chain via RhoA Signaling Cascade2009
- Author(s)
  T. Mizutani, K. Kawabata, Y. Koyama, M. Takahashi, and H. Haga
- Journal Title
  
  Cell Motility and the Cytoskeleton
  
  Volume : 66巻 Pages : 389-397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570158
[Journal Article] Mechanical Response to Isotropic Shrinkage of Fibroblasts Measured by canning Probe Microscopy2008
- Author(s)
  T. Kawamoto, H. Haga, K. Tamura, T.Mizutani and K. Kawabata
- Journal Title
  
  Japanese Journal of Applied Physics 47
  
  Pages : 6173-6176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Development of a Device to Stretch Tissue-like Materials and to Measure Their Mechanical Properties by Scanning Probe Microscopy2007
- Author(s)
  T. Mizutani, H. Haga, K. Kawabta
- Journal Title
  
  Acta Biomaterialia 3
  
  Pages : 485-493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Collective Movement and Morphogenesis of Epithelial Cells2007
- Author(s)
  H. Haga and K. Kawabata
- Journal Title
  
  Proceedings of the international symposium on topological aspects of critical systems and netwrks
  
  Pages : 82-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Visualization of stretch-induc intracellular teal response of single fibroblasts by mechanical scaning probe microscopy2007
- Author(s)
  K. Tamura, T. Mizutani, H. Haga, K.Kawabata
- Journal Title
  
  Japanese Journal of Applied Physics 46
  
  Pages : 5631-5635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Imaging Mechanical Properties of Living Cells by Scanning Probe Microscoy2007
- Author(s)
  H. Haga, M. Nagayama and K. Kawabata
- Journal Title
  
  Crent Nanoscien 3
  
  Pages : 97-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Collective Movement and Morphogenesis of Epithelial Cells2007
- Author(s)
  H. Haga
- Journal Title
  
  Proceedings of the international symposium on topological aspects of critical systems and networks
  
  Pages : 82-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Imaging Mechanical Properties of Living Cells by Scanning Probe Microscopy2007
- Author(s)
  H. Haga
- Journal Title
  
  Current Nanoscience 3
  
  Pages : 97-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] The Role of Actin-Binding Protein Filamin A in Cellular Stiffness and Morphology Studied by Wide-Range Scanning Probe Microscopy2006
- Author(s)
  K. Kato, Y. Ohmori, T. Mizutani, H. Haga Kohashi, T. Ito, and K. Kawabata
- Journal Title
  
  Japanese Journal of Applied Physics 45
  
  Pages : 2328-2332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Diphosphorylation of the Myosin Regulatory Light Chain Enhancs the Tension Acting on Stress Fibers in Fibroblasts2006
- Author(s)
  T. Mizutani, H. Haga. Y. Koyama, M.Takahashi, K. Kawabata
- Journal Title
  
  Journal of Cellular Physiology 209
  
  Pages : 726-731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Observation of Stiff Domain Structure on Collagen Gels by Wide-Range Scanning Probe Microscopy2006
- Author(s)
  T. Mizutani, H. Haga, K. Kato, K. Matsuda, and K. Kawabata
- Journal Title
  
  Japanese Journal of Applied Physics 45
  
  Pages : 2353-2356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18340122
[Journal Article] Collective Movement of Epithelial Cells on a Collagen Gel Substrate2005
- Author(s)
  Hisashi Haga
- Journal Title
  
  Biophys.J. 88
  
  Pages : 2250-2256
- Data Source
  KAKENHI-PROJECT-14780536
[Journal Article] Collective Movement of Epithelial Cells on a Collagen Gel Substrate2005
- Author(s)
  Hisashi Haga
- Journal Title
  
  Biophys.J. 88
  
  Pages : 2250-2256
- Data Source
  KAKENHI-PROJECT-15650051
[Presentation] 細胞外基質の粘弾性に応答する上皮細胞の集団運動と3次元形態形成2016
- Author(s)
  芳賀　永
- Organizer
  第54回日本生物物理学会年会シンポジウム
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Invited
- Data Source
  KAKENHI-INTERNATIONAL-15K21726
[Presentation] Fascin-1 promotes cancer cell invasion via activation of Stat32016
- Author(s)
  Toshiki Takahashi, Akihiro Nukuda, Masayuki Kano, Hisahiro Matsubara, and Hisashi Haga
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] 転写因子ATF5による多様ながん細胞株の浸潤促進2016
- Author(s)
  温田晃弘, 安田元昭, 水谷武臣, 川端和重, 芳賀永
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] Role of ATF5 in cancer cell invasion of several diverse human cancer cell lines2016
- Author(s)
  Akihiro Nukuda, Motoaki Yasuda, and Hisashi Haga
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] 細胞外基質の粘弾性に応答する上皮細胞の集団運動と3次元形態形成2016
- Author(s)
  芳賀永
- Organizer
  第54回日本生物物理学会年会
- Place of Presentation
  つくば国際会議場（茨城県・つくば市）
- Invited
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] 3D morphogensis of epithelial cells responding to viscoelasticity of the extracellular matrix2016
- Author(s)
  Hisashi Haga
- Organizer
  Japan-Austria joint meeting "Understanding the logic behind developmental dynamics
- Place of Presentation
  IST, Klosterneuburg（Austria）
- Invited
- Data Source
  KAKENHI-PLANNED-15H05858
[Presentation] Activating transcription factor 5 promotes cancer cell invasion through transcriptional activation of integrins2015
- Author(s)
  Akihiro Nukuda, Hiroki Endo, Seiichiro Ishihara, Motoaki Yasuda, Takeomi Mizutani, Kazushige Kawabata, and Hisashi Haga
- Organizer
  2015 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  サンディエゴ（アメリカ合衆国）
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] 基質の硬さによって促進される大腸がん細胞の悪性化：転写因子YAPを介した基質分解酵素MMP-7の発現亢進2015
- Author(s)
  温田晃弘, 石原誠一郎, 水谷武臣, 中村公則, 綾部時芳, 川端和重, 芳賀永
- Organizer
  第67回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] Activating transcription factor 5 promotes invasion of cancer cells via transcriptional activation of integrins2015
- Author(s)
  Akihiro Nukuda, Seiichiro Ishihara, Motoaki Yasuda, and Hisashi Haga
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] Collective migration of Madin-Darby canine kidney cells led by leader cells is dependent on Rac1,integrin beta1,and PI3K2014
- Author(s)
  N.Yamaguchi, T.Mizutani, K.Kawabata, and H.Haga
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良県新公会堂（奈良県春日野町）
- Year and Date
  2014-06-11
- Data Source
  KAKENHI-PUBLICLY-26106702
[Presentation] 3D tulip hat-like morphogenesis on deformable substrate induced by cellular contractile force2014
- Author(s)
  M. Imai, T. Mizutani, K. Kawabata, and H. Haga
- Organizer
  International Symposium on 3D Tissue Fabrication
- Place of Presentation
  東京大学生産技術研究（東京都）
- Data Source
  KAKENHI-PUBLICLY-25127701
[Presentation] Epithelial sheet folding triggers a luminal structure of Madin-Darby canine kidney cells in a collagen gel2014
- Author(s)
  S. Ishida, R. Tanaka, N. Yamaguchi, N. Ishikawa, G. Ogata, T. Mizutani, K. Kawabata, and H. Haga
- Organizer
  International Symposium on 3D Tissue Fabrication
- Place of Presentation
  東京大学生産技術研究（東京都）
- Data Source
  KAKENHI-PUBLICLY-25127701
[Presentation] Live cell imaging of collective migration in 3D morphogenesis of epithelial cells2012
- Author(s)
  今井美沙子、水谷武臣、川端和重、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Involvement of cell polarity in folding phenomena of epithelial sheets2012
- Author(s)
  石田すみれ、田中良昌、水谷武臣、川端和重、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-24370069
[Presentation] Involvement of cell polarity and cell migration in folding phenomena of epith elial sheets2012
- Author(s)
  S. Ishida, R. Tanaka, N. Yamaguchi, T. Mizutani, K. Kawabata, H. Haga
- Organizer
  第52回米国細胞生物学会年会
- Place of Presentation
  モスコーンセンター(米国,サンフランシスコ)
- Data Source
  KAKENHI-PROJECT-24370069
[Presentation] Live cell imaging of collective migration in 3D morphogenesis of epithelial cells2012
- Author(s)
  今井美沙子、水谷武臣、川端和重、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-24370069
[Presentation] Invasive migration of irradiation-survived human lung adenocarcinoma cells in 3D matrix2012
- Author(s)
  芳賀永
- Organizer
  第31回札幌国際がんシンポジウム
- Place of Presentation
  北海道大学（札幌市）
- Invited
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Collective behavior of epithelial cells responding to stiffness, roughness and composition of extracellular matrix2012
- Author(s)
  芳賀永
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡市）
- Invited
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] A stiff substrate activates transcription factor NF-B and increases the adhesion area in cancer cells2012
- Author(s)
  石原誠一郎、安田元昭、芳賀永
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  さっぽろ芸文館（北海道）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] EGFR and Integrin α2β1 Dependent Invasiveness of Lung Adenocarcinoma Cells that Survived 10 Gy Ionizing Radiation2012
- Author(s)
  X. Li, S. Ishihara, M. Yasuda, T. Mizutani, K. Kawabata, T. Nishioka, H. Haga
- Organizer
  第52回米国細胞生物学会年会
- Place of Presentation
  モスコーンセンター（米国）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Involvement of cell polarity and cell migration in folding phenomena of epithelial sheets2012
- Author(s)
  S. Ishida, R. Tanaka, N. Yamaguchi, T. Mizutani, K. Kawabata, H. Haga
- Organizer
  第52回米国細胞生物学会年会
- Place of Presentation
  モスコーンセンター（米国）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Invasive Migration ofIrradiation Survived Human LungAdenocarcinoma Cells in 3D Matrix2012
- Author(s)
  芳賀永
- Organizer
  第31回札幌国際がんシンポジウム(招待講演)
- Place of Presentation
  北海道大学(札幌市)
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Substrate stiffness enhances MMP-7 expression and ECM degradation in cancer cells2012
- Author(s)
  佐々木千絵、桝田浩孝、中村公則、綾部時芳、水谷武臣、川端和重、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Integrin α2 dependent increased invasiveness of lung adenocarcinoma cells that survived 10 Gy ionizing radiation2012
- Author(s)
  李雪、石原誠一郎、山田泰士、安田元昭、水谷武臣、川端和重、西岡健、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Involvement of cell polarity in folding phenomena of epithelial sheets2012
- Author(s)
  石田すみれ、田中良昌、水谷武臣、川端和重、芳賀永
- Organizer
  第64回日本細胞生物学会大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Collective behavior of epithelial cells responding to stiffness, roughness and Composition of extracellular matrix2012
- Author(s)
  芳賀永
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場(福岡市)(招待講演)
- Data Source
  KAKENHI-PROJECT-24370069
[Presentation] Invasive migration of irradiation-survived human lung adenocarcinoma cells in 3D matrix2012
- Author(s)
  芳賀永
- Organizer
  第31回札幌国際がんシンポジウム
- Place of Presentation
  北海道大学(札幌市)(招待講演)
- Data Source
  KAKENHI-PROJECT-24370069
[Presentation] 細胞外基質の硬さ・表面形状・組成に応答する上皮細胞の集団協調運動2011
- Author(s)
  芳賀永
- Organizer
  口腔先端応用医科学研究会第3回学術会議
- Place of Presentation
  東京医科歯科大(東京都) 招待講演
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] NF-k B expression in cancer cells regulated by substrate stiffness2011
- Author(s)
  石原誠一郎、安田元昭、水谷武臣、川端和重、芳賀永
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 軟らかい基質がもたらす上皮細胞集団の協調運動2011
- Author(s)
  芳賀永
- Organizer
  日本動物学会第82回大会
- Place of Presentation
  旭川市大雪クリスタルホール(北海道)(招待講演)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Collective behavior of epithelial cells responding to stiffness of the extracellular matrix2011
- Author(s)
  芳賀永
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学(札幌市)(招待講演)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Substrate stiffness regulates NF-k B expression and malignancy in cancer cells2011
- Author(s)
  石原誠一郎、安田元昭、水谷武臣、川端和重、芳賀永
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 細胞外基質の硬さ・表面形状・組成に応答する上皮細胞の集団協調運動2011
- Author(s)
  芳賀永
- Organizer
  口腔先端応用医科学研究会第3回学術会議
- Place of Presentation
  東京医科歯科大(東京都) 招待講演
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] Collective behavior of epithelial cells responding to stiffness of the extracellular matrix2011
- Author(s)
  芳賀永
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学(札幌市)(招待講演)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 軟らかい基質がもたらす上皮細胞集団の協調運動2011
- Author(s)
  芳賀永
- Organizer
  日本動物学会第82回大会
- Place of Presentation
  旭川市大雪クリスタルホール(北海道)(招待講演)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 細胞外基質の硬さ・表面形状・組成に応答する上皮細胞の集団協調運動2011
- Author(s)
  芳賀永
- Organizer
  口腔先端応用医科学研究会第3回学術会議
- Place of Presentation
  東京医科歯科大学
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] Collective behavior of epithelial cells responding to stiffness of the extracellular matrix2011
- Author(s)
  芳賀永
- Organizer
  第63回日本細胞生物学会大会
- Place of Presentation
  北海道大学
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 軟らかい基質がもたらす上皮細胞集団の協調運動2011
- Author(s)
  芳賀永
- Organizer
  日本動物学会第82回大会
- Place of Presentation
  旭川市大雪クリスタルホール
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] Substrate stiffness regulates NF-k B expression and activity in cancer cells2011
- Author(s)
  S.Ishihara, M.Yasuda, T.Mizutani, K.Kawabata, H.Haga
- Organizer
  第51回米国細胞生物学会年会
- Place of Presentation
  Colorado Convention Center (USA)
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 上皮細胞の集団運動と3次元形態形成2010
- Author(s)
  芳賀永
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場(神戸) 招待講演
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Enhancement of NE- EIB Expression and Malignancy of Cancer Cells Induced by Substrate Stiffness2010
- Author(s)
  S.Ishihara, M.Yasuda, T.Mizutani, K.Kawabata, H.Haga
- Organizer
  第50回米国細胞生物学会年会
- Place of Presentation
  Pennsylvania Convention Center(アメリカ)
- Year and Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 培養基質の硬さがもたらす細胞集団の協調運動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  第1回バイオエンジニアリングサマースクールin Sapporo
- Place of Presentation
  北海道医療大学サテライトキャンパス(石狩) 招待講演
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 基質の硬さがもたらす転写因子NF-κBの発現2010
- Author(s)
  石原誠一郎、安田元昭、水谷武臣、川端和重、芳賀永
- Organizer
  第5回メカノセンシング研究会
- Place of Presentation
  京都大学(京都)
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 培養基質の硬さがもたらす細胞集団の協調運動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  第1回バイオエンジニアリングサマースクールin Sapporo
- Place of Presentation
  北海道医療大学・サテライトキャンパス(札幌市) 招待講演
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 細胞外基質の硬さおよび組成に応答する細胞集団の協調挙動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  北海道医療大学個体差研セミナー
- Place of Presentation
  北海道医療大学(当別町) 招待講演
- Year and Date
  2010-04-02
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 上皮細胞の集団運動と3次元形態形成2010
- Author(s)
  芳賀永
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場(神戸市) 招待講演
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 細胞外基質の硬さおよび組成に応答する細胞集団の協調挙動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  北海道医療大学個体差研セミナー
- Place of Presentation
  北海道医療大学(石狩) 招待講演
- Year and Date
  2010-04-02
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 3次元培養環境においてみられる放射線照射後に生残した肺がん細胞の浸潤機構2010
- Author(s)
  石原誠一郎、安田元昭、武島嗣英、水谷武臣、川端和重、西岡健、芳賀永
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Integrin Dependent Invasive Mmigration in 3D Collagen Matrix of Human Lung Adenocarcinoma Cells that Survived 10Gy Iirradiation2010
- Author(s)
  S.Ishihara, M.Yasuda, T.Takeshima, T.Mizutani, K.Kawabata, T.Nishioka, H.Haga
- Organizer
  札幌国際がんシンポジウム2010
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2010-06-28
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] Invasive Mechanism of Lung Adenocarcinoma Cells Revealed by 3D Collagen Culture2010
- Author(s)
  S.Ishihara, M.Yasuda, T.Takeshima, T.Mizutani, K.Kawabata, T.Nishioka, H.Haga
- Organizer
  第57回マトリックス研究会大会
- Place of Presentation
  秋田拠点センター・アルヴェ(秋田)
- Year and Date
  2010-08-19
- Data Source
  KAKENHI-PROJECT-21249065
[Presentation] 上皮細胞の集団運動と3次元形態形成2010
- Author(s)
  芳賀永
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 細胞外基質の硬さおよび組成に応答する細胞集団の協調挙動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  北海道医療大学個体差研セミナー
- Place of Presentation
  北海道医療大学
- Year and Date
  2010-04-02
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 培養基質の硬さがもたらす細胞集団の協調運動と形態形成2010
- Author(s)
  芳賀永
- Organizer
  第1回バイオエンジニアリングサマースクール
- Place of Presentation
  北海道医療大学・サテライトキャンパス
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 3D Morphogenesis and Collective Migration of Epithelial Cells Observed on a Soft Substrate Containing Laminin2009
- Author(s)
  H.Haga, et al.
- Organizer
  第49回米国細胞生物学会年会
- Place of Presentation
  米国・サンディエゴ市・コンベンションセンター
- Year and Date
  2009-12-08
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 3D Morphogenesis and Collective Migration of Epithelial Cells Observed on a Soft Substrate Containing Laminin2009
- Author(s)
  芳賀永
- Organizer
  第49回米国細胞生物学会年会
- Place of Presentation
  サンディエゴコンベンションセンター
- Year and Date
  2009-12-08
- Data Source
  KAKENHI-PROJECT-21570158
[Presentation] 細胞系における協調運動に伴う局所弾性率の時空間測定2007
- Author(s)
  芳賀永
- Organizer
  日本表面科学会第27回表面科学講演大会招待講演
- Place of Presentation
  東京都
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-18340122
[Presentation] 細胞系における協調運動に伴う局所弾性率の時空間測定2007
- Author(s)
  芳賀永
- Organizer
  日本表面科学会第27回表面科学講演大会
- Place of Presentation
  東京
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-18340122
[Presentation] Activating transcription factor 5 enhances radioresistance and malignant phenotypes in lung cancer cells
- Author(s)
  S. Ishihara, M. Yasuda, T. Nishioka, and H. Haga
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] Invasive ability is regulated by activating transcription factor 5 in high invasive cancer cells
- Author(s)
  H. Endoh, S. Ishihara, T. Nishioka, M. Yasuda, and H. Haga
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] Substrate stiffness enhances expression of matrix metalloproteinase 7 via myosin phosphorylation in colon cancer cells
- Author(s)
  A. Nukuda, S. Ishihara, K. Nakamura, T. Ayabe, and H. Haga
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26430104
[Presentation] Collective migration of Madin-Darby canine kidney cells led by leader cells is dependent on Rac1, integrin beta1, and PI3K
- Author(s)
  N. Yamaguchi, T. Mizutani, K. Kawabata, and H.i Haga
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良県新公会堂（奈良県春日野町）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PUBLICLY-25127701

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HAGA Hisashi 芳賀 永

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がん細胞に集団浸潤を誘引する接触追従の機序解明と普遍性の検証Principal InvestigatorOngoing

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3D morphologicOngoing

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３Ｄ形態ロジックの国際共同研究を加速するバーチャル研究所Ongoing

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インビトロ系における細胞シートからの３Ｄ形態形成Principal InvestigatorOngoing

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Stiff Substrates Enhances ATF5-Signaling-Mediated Invasive Ability in Cancer CellsPrincipal Investigator

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ゲル基質の軟らかさと粘性を利用した上皮シートの3次元組織構築Principal Investigator

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多数の細胞の力と運動がもたらす管腔構造形成のロジックPrincipal Investigator

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Collective migration of epithelial cells induced by softness of substratesPrincipal Investigator

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HAGA Hisashi 芳賀永