Aoki Miho 粟生木美穂

… Alternative Names

粟生木美穂アオキミホ

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Researcher Number	10783227
Affiliation (Current)	2026: 福島県立医科大学, 公私立大学の部局等, 助手
Affiliation (based on the past Project Information) *help	2023: 福島県立医科大学, 公私立大学の部局等, 助手 2016 – 2021: 福島県立医科大学, 公私立大学の部局等, 助手
Review Section/Research Field	Principal Investigator Radiation science Except Principal Investigator Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator 加速器 / 核医学 / 放射線、Ｘ線、粒子線 / 前立腺がん / α線 / 放射性薬剤 / 分析科学 / 放射線 / 内用放射線治療 / 癌 / GRP受容体 / ペプチド … More Except Principal Investigator … More アスタチン / アスタチン-211 / RI内用療法 / 核医学治療 / 抗CD82抗体 / α線放出核種 / 抗CDX抗体 / アスタチン-211標識抗体 / 標的アルファ線治療 / 急性骨髄性白血病 / 抗CD82抗体α線標的治療 / ヒト化白血病モデルマウス / 抗hCD82ヒト化キメラmAb / 急性白血病 / 白血病幹細胞 / アルファ線標的治療 / CD82抗原 / ドジメトリー / アビジン / ビオチン / α線 / アイソトープ治療 / プレターゲティング / 癌 / 治療用放射性薬剤 / チミジンホスホリラーゼ / アルファ線 / 内用療法 / イメージング / ペプチド / プローブ / セラノスティクス / がん / 核医学 Less

Optimization of pretargeted alpha therapy for multiple types of cancer
- Principal Investigator
  
  Washiyama Kohshin
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Fukushima Medical University
Development of an innovative leukemia therapy using alpha-particle-emitting nuclides targeting cancer stem cells
- Principal Investigator
  
  ZHAO Songji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Fukushima Medical University
PD-ECGF targeted tumor treatment with new At-211 radiolabeled uracil derivatives
- Principal Investigator
  
  NISHIJIMA Ken-ichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Fukushima Medical University
Establishment of comprehensive cancer diagnosis and therapy using radio halogen
- Principal Investigator
  
  OGAWA KAZUMA
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
Investigation for diagnosis and treatment of prostate cancer using radiohalogen labeled Bombesin derivativePrincipal Investigator
- Principal Investigator
  
  Aoki Miho
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Radiation science
- Research Institution
  Fukushima Medical University

All 2024 2023 2022 2021 2020 2019 2017

All Journal Article Presentation

[Journal Article] In vivo-stable bis-iminobiotin for targeted radionuclide delivery with the mutant streptavidin2024
- Author(s)
  Toshifumi Tatsumi, Songji Zhao, Akitomo Kasahara, Miho Aoki, Ken-ichi Nishijima, Naoyuki Ukon, Tatsuhiko Kodama, Kazuhiro Takahashi, Akira Sugiyama, Kohshin Washiyama, Kenzo Yamatsugu, Motomu Kanai
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 108 Pages: 129803-129803
- DOI
  10.1016/j.bmcl.2024.129803
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627, KAKENHI-ORGANIZER-22H05017, KAKENHI-PLANNED-22H05018, KAKENHI-PLANNED-22H05024, KAKENHI-PROJECT-22K07800, KAKENHI-PROJECT-21K15831, KAKENHI-PROJECT-24K18788
[Journal Article] Preliminary Evaluation of Astatine-211-Labeled Bombesin Derivatives for Targeted Alpha Therapy2020
- Author(s)
  Aoki Miho、Zhao Songji、Takahashi Kazuhiro、Washiyama Kohshin、Ukon Naoyuki、Tan Chengbo、Shimoyama Saki、Nishijima Ken-ichi、Ogawa Kazuma
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 68 Issue: 6 Pages: 538-545
- DOI
  10.1248/cpb.c20-00077
- NAID
  130007850061
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2020-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08180, KAKENHI-PROJECT-18K07630, KAKENHI-PROJECT-20H03626
[Journal Article] Human dosimetry of free 211At and meta-[211At]astatobenzylguanidine (211At-MABG) estimated using preclinical biodistribution from normal mice2020
- Author(s)
  Ukon Naoyuki、Zhao Songji、Washiyama Kohshin、Oriuchi Noboru、Tan Chengbo、Shimoyama Saki、Aoki Miho、Kubo Hitoshi、Takahashi Kazuhiro、Ito Hiroshi
- Journal Title
  
  EJNMMI Physics
  
  Volume: 7 Issue: 1 Pages: 58-58
- DOI
  10.1186/s40658-020-00326-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08031, KAKENHI-PROJECT-19H03605, KAKENHI-PROJECT-18K15556, KAKENHI-PROJECT-20H03627, KAKENHI-PROJECT-20H03626
[Journal Article] Possibility of cancer-stem-cell-targeted radioimmunotherapy for acute myelogenous leukemia using 211At-CXCR4 monoclonal antibody.2020
- Author(s)
  Oriuchi N
- Journal Title
  
  Sci. Rep.
  
  Volume: 10 Issue: 1 Pages: 6810-6810
- DOI
  10.1038/s41598-020-63557-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03548, KAKENHI-PROJECT-19K08180, KAKENHI-PROJECT-20K08031, KAKENHI-PROJECT-20K21582, KAKENHI-PROJECT-19H03605, KAKENHI-PROJECT-20H03626
[Presentation] Pretargeted alpha radioimmunotherapy for the treatment of gastric cancer using low-immunogenic mutated streptavidin and 211At labeled modified bis-iminobiotin2023
- Author(s)
  Kohshin Washiyama, Toshifumi Tatsumi, Akira Sugiyama, Songji Zhao, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  12th International Symposium on Targeted Alpha Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] Effects of single and repeated 211At-MABG treatments on tumor growth suppression in a pheochromocytoma xenograft2022
- Author(s)
  Zhao S, Aoki M, Ukon N, Shimoyama S, Nishijima KI, Joho T, Washiyama K, Washino K, Shiga T, Oriuchi N, Takahashi K, Higashi T, Ito H.
- Organizer
  The 69th Society of Nuclear Medicine Annual Meeting- Virtual Edition (SNMMI 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] Synthesis and evaluation of 211At-labeled bis-iminobiotin for pretargeted alpha radioimmunotherapy2022
- Author(s)
  Washiyama K, Sugiyama A, Tatsumi T, Zhao S, Aoki M, Yamatsugu K, Ukon N, Shimoyama S, Nishijima K, Joho T, Shiga T, Inano A, Oriuchi N, Kanai M, Takahashi K, Kodama T
- Organizer
  The 69th Society of Nuclear Medicine Annual Meeting- Virtual Edition (SNMMI 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] 急性骨髄性白血病における211At標識抗CD82抗体の治療効果2022
- Author(s)
  趙松吉、粟生木美穂、趙　景敏、右近直之、下山彩希、西嶋剣一、鷲山幸信、高橋和弘、伊藤　浩、織内　昇、池添隆之
- Organizer
  第３回放射線災害・医科学研究拠点ワークショップ
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] Synthesis of an 211At labelled bis-iminobiotin derivativewith enhanced plasma stability2022
- Author(s)
  Kohshin Washiyama, Toshifumi Tatsumi, Akira Sugiyama, Songji Zhao, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  2022 JSNM Annual Meeting
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] Synthesis and evaluation of 211At-labeled bis-iminobiotin for pretargeted alpha radioimmunotherapy2022
- Author(s)
  Kohshin Washiyama, Toshifumi Tatsumi, Akira Sugiyama, Songji Zhao, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  2022 SNMMI Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 低免疫原性ストレプトアビジン変異体と改変ビオチンを用いるプレターゲティングシステムの開発2022
- Author(s)
  巽俊文、山次健三、杉山暁、趙松吉、粟生木美穂、西嶋剣一、右近直之、下山彩希、譚成博、城寶大輝、織内昇、高橋和弘、清水洋平、高橋和希、安藝翔、児玉龍彦、鷲山幸信、金井求
- Organizer
  日本放射線化学会第66回討論会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] [211At]MABG注射液の品質試験：LCMSを用いた確認試験法の開発2021
- Author(s)
  西嶋剣一、粟生木美穂、城寶大輝、鷲山幸信、佐々木茂範、望月一優、塩入大護、髙橋和弘
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] 急性骨髄性白血病における211At標識抗CD82抗体の治療効果2021
- Author(s)
  趙松吉、粟生木美穂、趙　景敏、右近直之、下山彩希、西嶋剣一、鷲山幸信、高橋和弘、伊藤　浩、織内　昇、池添隆之。
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] ヒト急性白血病モデルマウスにおける211At-CD33の体内動態2021
- Author(s)
  下山彩希、粟生木美穂、趙　景敏、右近直之、西嶋剣一、鷲山幸信、高橋和弘、伊藤　浩、織内　昇、池添隆之、趙松吉
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] Evaluation of acute radiotoxicity profile of alpha-particle-emitting meta-211At-astato-benzylguanidine (211At-MABG) in normal BALB/c mice2021
- Author(s)
  Zhao S, Washino k, Aoki M, Ukon N, Shimoyama S, Nishijima K, Washiyama K, Ito N, Yoshioka N, Tamura N, Takahashi K, Higashi T, Ito H
- Organizer
  The 68th Society of Nuclear Medicine Annual Meeting- Virtual Edition (SNMMI 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] 褐色細胞腫モデルにおける211At-MABGの反復投与による腫瘍成長の抑制効果の評価2021
- Author(s)
  趙松吉;粟生木美穂;下山彩希、右近直之、西嶋剣一、鷲野弘明、志賀哲、織内昇、髙橋和弘、東達也、伊藤浩
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] 正常マウスにおけるフリー 211Atの臓器毒性評価2021
- Author(s)
  趙松吉、粟生木美穂、右近直之、下山　彩希、西嶋剣一、鷲山　幸信、志賀　哲、織内　昇、高橋和弘、伊藤　浩
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] ヒト急性白血病モデルマウスにおける211At-CD82の体内動態2021
- Author(s)
  趙松吉、粟生木美穂、下山彩希、趙　景敏、右近直之、西嶋剣一、鷲山幸信、高橋和弘、伊藤　浩、織内　昇、池添隆之
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] Targeted delivery of 211At with low immunogenic mutant streptavidin-bisiminobiotin pre-targeting system2021
- Author(s)
  Toshifumi Tatsumi, Kenzo Yamatsugu, Akira Sugiyama, Songji Zhao, Miho Aoki, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Chengbo Tan, Fengying Gao, Taiki Joho, Noboru Oriuchi, Kazuhiro Takahashi, Motomu Kanai, Tatsuhiko Kodama, Kohshin Washiyama
- Organizer
  The 2021 International Chemical Congress of Pacific Basin Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] Feasibility of cancer stem cells-targeted radioimmunotherapy for acute myelogenous leukemia with 211At-CXCR4 monoclonal antibody.2020
- Author(s)
  Oriuchi N, Aoki M, Ukon N, Washiyama K, Shimoyama S, Nishijima K, Takahashi K, Ito H, Ikezoe K, Zhao S
- Organizer
  2020米国核医学・分子イメージング学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] イミノビオチン誘導体の合成とアスタチン標識の検討2020
- Author(s)
  粟生木美穂, 巽俊文, 西嶋剣一, 山次健三, 城寶大輝, 趙松吉, 杉山暁, 児玉龍彦, 高橋和弘, 金井求, 鷲山幸信
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] プレターゲティングへの応用を目指した211At標識改変イミノビオチンの体内分布測定2020
- Author(s)
  鷲山幸信, 巽俊文, 杉山暁, 粟生木美穂, 譚成博, 下山彩希, 山次健三, 金井求, 児玉龍彦, 趙松吉, 高橋和弘
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] コンパニオン診断薬としての123I-MIBGから推定した211At-MABGの線量評価検討2020
- Author(s)
  右近直之、趙松吉、鷲野弘明、吉永恵一郎、粟生木美穂、西嶋剣一、鷲山幸信、織内昇、高橋和弘、東達也、伊藤浩
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] 正常マウスにおける211At-MABG と123I-MIBGの放射線線量の比較評価2020
- Author(s)
  Zhao S, Ukon N, Yoshinaga K, Washino K, Aoki M, Nishijima K, Shimoyama S, Tan C, Washiyama K, Oriuchi N, Ito N, Yoshioka N, Tamura N, Takahashi K, Higashi T, Ito H
- Organizer
  日本放射線影響学会第63回大会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] コンパニオン診断薬としての123I-MIBGから推定した211At-MABGの線量評価検討2020
- Author(s)
  右近直之, 趙松吉, 鷲野弘明, 吉永恵一郎, 粟生木美穂, 西嶋剣一, 鷲山幸信, 織内昇, 高橋和弘, 東達也, 伊藤浩
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] Development of a pre-targeting strategy of low-immunogenic mutated streptavidin with 211At labeled modified biotin for advanced cancer treatment2020
- Author(s)
  Kohshin Washiyama, Akira Sugiyama, Songji Zhao, Toshifumi Tatsumi, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Chengbo Tan, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  SNMMI 2020 Annual Meeting - Virtual Edition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 色細胞腫モデルにおける211At-MABGと 131I-MIBGの抗腫瘍効果および暗線性の比較2020
- Author(s)
  Yoshinaga K, Zhao S, Washino K, Aoki M, Nishijima K, Shimoyama S, Ukon N, Gao F, Washiyama K, Ito N, Yoshioka N, Tamura N, Takahashi K, Higashi T, Ito H
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] Differences and similarities in biodistribution, pharmacokinetics and metabolites of 211At-MABG versus 123I-MIBG in normal mice2020
- Author(s)
  Washino K, Zhao S, Yoshinaga K, Ito Y, Aoki M, Ukon N, Shimoyama S, Nishijima K, Washiyama K, Ito N, Yoshioka N, Tamura N, Takahashi K, Ito H, Higashi T
- Organizer
  The 67th Society of Nuclear Medicine Annual Meeting (SNMMI 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] Search for the optimal bis-iminobiotin for the pretargeting strategy using a mutated low immunogenic streptavidin2020
- Author(s)
  K. Washiyama, T. Tatsumi, S. Zhao, A. Sugiyama, M. Aoki, K. Yamatsugu, N. Ukon, K. Nishijima, S. Shimoyama, C. Tan, T. Joho, N. Oriuchi, M. Kanai, K. Takahashi, T. Kodama
- Organizer
  33th Annual Congress of the European Association of Nuclear Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] Biodistribution and dosimetry studies for the optimization of pre-targeted radionuclide therapy using 211At-labeled modified biotin2020
- Author(s)
  Kohshin Washiyama, Akira Sugiyama, Songji Zhao, Toshifumi Tatsumi, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  33th Annual Congress of the European Association of Nuclear Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 褐色細胞腫モデルにおける211At-MABGと 131I-MIBGの抗腫瘍効果および安全性の比較2020
- Author(s)
  Yoshinaga K, Zhao S, Washino K, Aoki M, Nishijima K, Shimoyama S, Ukon N, Gao F, Washiyama K, Ito N, Yoshioka N, Tamura N, Takahashi K, Higashi T, Ito H
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] α放射体211At標識イミノビオチンの作成と安定性評価2020
- Author(s)
  鷲山幸信、粟生木美穂、巽俊文、山次健三、杉山暁、西嶋剣一、城寶大輝、高峰英、趙松吉、金井求、児玉龍彦、高橋和弘
- Organizer
  日本放射化学会第64回討論会(2020)
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 進行がん治療を指向した低免疫原性ストレプトアビジン変異体と 211At標識イミノビオチンを用いるプレターゲティングシステムの開発2020
- Author(s)
  巽俊文, 山次健三, 清水洋平, 杉山暁, 趙松吉, 粟生木美穂, 西嶋剣一, 右近直之, 高橋和弘, 児玉龍彦, 鷲山幸信, 金井求
- Organizer
  反応と合成の進歩2020特別企画シンポジウム|
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 正常マウスにおける211At-MABGの血液毒性の用量反応関係2020
- Author(s)
  鷲野弘明, 趙松吉, 下山彩希, 吉岡菜穂, 伊東奈津江, 粟生木美穂, 右近直之, 吉永恵一郎, 高橋和弘, 伊藤浩, 東達也
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] Effects of alpha-emitting meta-211At-astato-benzylguanidine (211At-MABG) compared to 131I-meta-iodobenzylguanidine (131I-MIBG) on tumor growth suppression in a pheochromocytoma mouse model2020
- Author(s)
  Yoshinaga K, Zhao S, Washino K, Aoki M, Nishijima K, Shimoyama S, Ukon N, Gao F, Washiyama K, Ito N, Yoshioka N, Tamura N, Takahashi K, Ito H, Higashi T
- Organizer
  ENDO2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] α放射体211Atを用いたプレターゲティング法による進行がんの治療2020
- Author(s)
  Kohshin Washiyama, Akira Sugiyama, Kenzo Yamatsugu, Songji Zhao, Toshifumi Tatsumi, Miho Aoki, Naoyuki Ukon, Saki Shimoyama, Ken-ichi Nishijima, Chengbo Tan, Taiki Joho, Fengying Gao, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  日本放射線影響学会第63回大会
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] Effects and safety of alpha-emitting meta-211At-astato-benzylguanidine (211At-MABG) compared with 131I-meta-iodobenzylguanidine (131I-MIBG) on tumor growth suppression in a pheochromocytoma mouse model2020
- Author(s)
  Zhao S, Yoshinaga K, Washino K, Aoki M, Nishijima K, Shimoyama S, Ukon N, Gao F, Washiyama K, Ito N, Yoshioka N, Tamura N, Takahashi K, Higashi T, Ito H
- Organizer
  The 67th Society of Nuclear Medicine Annual Meeting (SNMMI 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] Effects and safety of alpha-emitting meta-211At-astato-benzylguanidine (211At-MABG) compared with 131I-meta-iodobenzylguanidine (131I-MIBG) on tumor growth suppression in a pheochromocytoma mouse model.2020
- Author(s)
  Zhao S, Yoshinaga K, Washino K, Aoki M, Nishijima K, Shimoyama S, Ukon N, Gao F, Washiyama K, Ito N, Yoshioka N, Tamura N, Takahashi K, Higashi T, Ito H
- Organizer
  2020米国核医学・分子イメージング学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] Evaluation of therapeutic effect of the targeted alpha therapy using Cupid-211At-labeled Psyche-B pretargeting system in a human gastric cancer cell xenograft2020
- Author(s)
  Zhao S, Sugiyama A, Ukon N, Shimoyama S, Tatsumi T, Aoki M, Gao F, Yamatsugu K, Nishijima K, Joho T, Oriuchi N, Takahashi K, Kanai M, Kodama T, Washiyama K
- Organizer
  Annual Congress of the European Association of Nuclear Medicine (EANM'20)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] Feasibility of cancer stem cells-targeted radioimmunotherapy for acute myelogenous leukemia with 211At-CXCR4 monoclonal antibody2020
- Author(s)
  Oriuchi N, Aoki M, Ukon N, Washiyama K, Shimoyama S, Nishijima K, Takahashi K, Ito H, Ikezoe K, Zhao S
- Organizer
  The 67th Society of Nuclear Medicine Annual Meeting (SNMMI 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] ヒト胃癌細胞移植担癌モデル動物におけるドラッグデリバリーシステム（Cupid-Psycheシステム）を用いたアルファ線の治療効果。2020
- Author(s)
  Zhao S, Sugiyama A, Shimoyama S, Tatsumi T, Ukon N, Gao F, Aoki M, Yamatsugu K, Takahashi K, Kanai M, Washiyama K
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] 正常マウスにおける211At-MABGの血液毒性の用量反応関係2020
- Author(s)
  鷲野　弘明、趙松吉、下山彩希、吉岡菜穂、伊東奈津江、粟生木美穂、右近直之、吉永恵一郎、高橋和弘、伊藤浩、東達也
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] 正常マウスにおける211At-MABGの毒性評価2020
- Author(s)
  趙松吉, 吉永恵一郎, 粟生木美穂, 右近直之, 下山彩希, 西嶋剣一, 鷲山幸信, 鷲野弘明, 高橋和弘, 東達也, 伊藤浩
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] Evaluation of therapeutic effect of the targeted alpha therapy using Cupid-211At-labeled Psyche-B pretargeting system in a human gastric cancer cell xenograft2020
- Author(s)
  Songji Zhao, Akira Sugiyama, Naoyuki Ukon, Saki Shimoyama, Toshifumi Tatsumi, Miho Aoki, Fengying Gao, Kenzo Yamatsugu, Ken-ichi Nishijima, Taiki Joho, Noboru Oriuchi, Kazuhiro Takahashi, Motomu Kanai, Tatsuhiko Kodama, Kohshin Washiyama
- Organizer
  33th Annual Congress of the European Association of Nuclear Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 正常マウスにおける211At-MABGの毒性評価2020
- Author(s)
  趙松吉、吉永恵一郎、粟生木美穂、右近直之、下山彩希、西嶋剣一、鷲山幸信、鷲野弘明、高橋和弘、東達也、伊藤浩
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03626
[Presentation] 211At-MABG吸収線量評価におけるコンパニオン診断薬123I-MIBGの活用核医学2019
- Author(s)
  吉永恵一郎, 趙松吉, 粟生木美穂, 右近直之, 下山彩希, 西嶋剣一, 鷲山幸信, 鷲野弘明, 高橋和弘, 伊藤浩, 東達也
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] Synthesis of [211At]MABG Using Remote-controlled Synthesizer and Quality Evaluation2019
- Author(s)
  M. Aoki, K. Minegishi, K. Nishijima, H. Suzuki, S. Sasaki, K. Washiyama, S. Zhao, K. Nagatsu, M. Zhang, K. Takahashi
- Organizer
  The 23rd International Symposium on Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] 正常マウスにおける123I-MIBGと211At-MABGの体内動態の評価2019
- Author(s)
  趙松吉, 吉永恵一郎, 粟生木美穂, 右近直之, 下山彩希, 西嶋剣一, 鷲山幸信, 鷲野弘明, 高橋和弘, 東達也, 伊藤浩
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] 211At標識抗CXCR4抗体の腫瘍移植マウスにおける体内分布2019
- Author(s)
  織内昇, 趙松吉, 粟生木美穂, 譚成博, 右近直之, 西嶋剣一, 鷲山幸信, 高橋和弘, 池添隆之, 伊藤浩
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] 小動物用SPECT装置を用いた211Atによる画像化の基礎検討2019
- Author(s)
  右近直之, 趙松吉, 鷲山幸信, 織内昇, 粟生木美穂, 西嶋剣一, 譚成博, 下山彩希, 久保均, 高橋和弘, 伊藤浩
- Organizer
  第14回日本分子イメージング学会学術総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] 正常マウスにおける211At-MABGの薬物動態と代謝産物の予備的評価2019
- Author(s)
  鷲野弘明, 趙松吉, 粟生木美穂, 右近直之, 下山彩希, 西嶋剣一, 鷲山幸信, 吉永恵一郎, 高橋和弘, 伊藤浩, 東達也
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] [211At]MABGの薄層クロマトグラフィー手順の探索2019
- Author(s)
  粟生木美穂, 西嶋剣一, 鷲山幸信, 城寶大輝, 下山彩希, 右近直之, 趙松吉, 鷲野弘明, 高橋和弘, 東達也, 伊藤浩
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08180
[Presentation] The Production of 211At at Fukushima Medical University2017
- Author(s)
  Aoki Miho, Tominaga Hideyuki, Kato Jun, Oda Takashi, Zhao Songji, Hiasa Toshikazu, Oriuchi Noboru, Seiichi Takenoshita
- Organizer
  10th International Symposium on Targeted Alpha Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07099

1. ZHAO Songji (80374239)

# of Collaborated Projects: 3 results

# of Collaborated Products: 48 results
2. OGAWA Kazuma (30347471)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NISHIJIMA Ken-ichi (60364254)

# of Collaborated Projects: 2 results

# of Collaborated Products: 32 results
4. Washiyama Kohshin (80313675)

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
5. 高橋和弘 (20370257)

# of Collaborated Projects: 2 results

# of Collaborated Products: 35 results
6. 杉山暁 (40562715)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
7. 右近直之 (70792985)

# of Collaborated Projects: 2 results

# of Collaborated Products: 31 results
8. 三代憲司 (60776079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 東川桂 (10756878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 久下裕司 (70321958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 山下雄史 (50615622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 横山明彦 (80230655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 巽俊文 (80868232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
14. 池添隆之 (80294833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
15. 織内昇 (40292586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
16. ITO Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 久保均

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Aoki Miho 粟生木 美穂

粟生木 美穂 アオキ ミホ

Research Projects

Research Products

Co-Researchers

Optimization of pretargeted alpha therapy for multiple types of cancer

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Development of an innovative leukemia therapy using alpha-particle-emitting nuclides targeting cancer stem cells

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PD-ECGF targeted tumor treatment with new At-211 radiolabeled uracil derivatives

Principal Investigator

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Review Section

Research Institution

Establishment of comprehensive cancer diagnosis and therapy using radio halogen

Principal Investigator

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Review Section

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Investigation for diagnosis and treatment of prostate cancer using radiohalogen labeled Bombesin derivativePrincipal Investigator

Principal Investigator

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[Journal Article] In vivo-stable bis-iminobiotin for targeted radionuclide delivery with the mutant streptavidin2024

Author(s)

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DOI

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[Journal Article] Preliminary Evaluation of Astatine-211-Labeled Bombesin Derivatives for Targeted Alpha Therapy2020

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[Journal Article] Human dosimetry of free 211At and meta-[211At]astatobenzylguanidine (211At-MABG) estimated using preclinical biodistribution from normal mice2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Possibility of cancer-stem-cell-targeted radioimmunotherapy for acute myelogenous leukemia using 211At-CXCR4 monoclonal antibody.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Pretargeted alpha radioimmunotherapy for the treatment of gastric cancer using low-immunogenic mutated streptavidin and 211At labeled modified bis-iminobiotin2023

Author(s)

Organizer

Data Source

[Presentation] Effects of single and repeated 211At-MABG treatments on tumor growth suppression in a pheochromocytoma xenograft2022

Author(s)

Organizer

Data Source

[Presentation] Synthesis and evaluation of 211At-labeled bis-iminobiotin for pretargeted alpha radioimmunotherapy2022

Author(s)

Organizer

Data Source

[Presentation] 急性骨髄性白血病における211At標識抗CD82抗体の治療効果2022

Author(s)

Organizer

Data Source

[Presentation] Synthesis of an 211At labelled bis-iminobiotin derivativewith enhanced plasma stability2022

Author(s)

Organizer

Data Source

[Presentation] Synthesis and evaluation of 211At-labeled bis-iminobiotin for pretargeted alpha radioimmunotherapy2022

Aoki Miho 粟生木美穂

粟生木美穂アオキミホ