Tatsumi Toshifumi 巽俊文

Researcher Number	80868232
Other IDs
Affiliation (Current)	2025: 東京大学, アイソトープ総合センター, 特任助教
Affiliation (based on the past Project Information) *help	2023 – 2025: 東京大学, アイソトープ総合センター, 特任助教 2020 – 2024: 東京大学, 大学院薬学系研究科(薬学部), 特別研究員 2020: 東京大学, 大学院薬学系研究科(薬学部), 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields / Medium-sized Section 52:General internal medicine and related fields / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator ドラッグデリバリーシステム / クリアランス薬剤 / 改変ストレプトアビジン / 改変ビオチン / プレターゲティング Except Principal Investigator α線放出核種 / タンパク分解 / 細胞連関 / オートファジー / アミロイド … More / 認知症 / セラノスティックス / ドラッグデリバリーシステム / セラノスティクス / PET / Antibody Drug Conjugate / HER2 / Axially Substituted / photosensitizer / Silicon Phthalocyanine / antibody mimetic / Psyche / Cupid / single domain antibody / antibody mimetics / duocarmyucin / nanobody / Yatakemycin / duocarmycin / antibody drug conjugate / DNAアルキル化剤 / duocarmycin SA / Ax-SiPc / VHH / Nanobody / Affibody / Cupid-Psyche / affibody / 抗体ミメティクス / 巻き戻し / デュオカルマイシン / 光増感剤 / VHH抗体 / ドラッグデリバリー / ドジメトリー / アスタチン-211 / アビジン / ビオチン / α線 / アイソトープ治療 / アスタチン / プレターゲティング / アクチニウム / ラジオセラノスティクス / 核医学治療 Less

Development of Cearing Agent to Innovate the Pre-targeting TherapyPrincipal Investigator
- Principal Investigator
  
  巽俊文
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  The University of Tokyo
α線放出核種と抗体ドラッグデリバリーシステムによる新規放射性医薬品の開発
- Principal Investigator
  
  和田洋一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  The University of Tokyo
Elucidation of the role of autophagy in photo-oxygenated amyloid degradation
- Principal Investigator
  
  富田泰輔
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
Creation of Next Generation Antibody Drug Conjugate Therapeutics for Advanced Cancer
- Principal Investigator
  
  Sugiyama Akira
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokyo
Collaborative Therapeutic Isotope Production and Radiopharmaceutical Synthesis
- Principal Investigator
  
  Wada Yuichiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  The University of Tokyo
Optimization of pretargeted alpha therapy for multiple types of cancer
- Principal Investigator
  
  Washiyama Kohshin
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Fukushima Medical University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] pH dependence of perturbed angular correlation in DOTA chelated $$^{111}$$In measured with ring-shape gamma-ray detectors2024
- Author(s)
  Shimazoe Kenji、Donghwan Kim、Mineo Tomoko、Sato Takeshi、Ohta Seiichi、Tatsumi Toshifumi、Sugiyama Akira、Yamatsugu Kenzo、Nomura Sachiyo、Terabayashi Ryohei、Tomita Hideki、Sonoda Tetsu、Shigekawa Yudai、Yokokita Takuya、Uenomachi Mizuki
- Journal Title
  
  Interactions
  
  Volume: 245 Issue: 1 Pages: 22-22
- DOI
  10.1007/s10751-024-01864-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18223, KAKENHI-PROJECT-20KK0174, KAKENHI-ORGANIZER-22H05017, KAKENHI-PLANNED-22H05018, KAKENHI-ORGANIZER-22H05021, KAKENHI-PLANNED-22H05022, KAKENHI-PLANNED-22H05024, KAKENHI-PROJECT-22H04961
[Journal Article] Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin2024
- Author(s)
  Sakata Juri、Tatsumi Toshifumi、Sugiyama Akira, et al.
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 214 Pages: 106375-106375
- DOI
  10.1016/j.pep.2023.106375
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15217, KAKENHI-PROJECT-22KJ0538, KAKENHI-PROJECT-20KK0174, KAKENHI-ORGANIZER-22H05017, KAKENHI-PLANNED-22H05018, KAKENHI-PLANNED-22H05024, KAKENHI-PROJECT-19H01032, KAKENHI-PROJECT-21H02601, KAKENHI-PROJECT-21H02779
[Journal Article] Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system2022
- Author(s)
  Yamatsugu Kenzo、Katoh Hiroto、Yamashita Takefumi、Takahashi Kazuki、Aki Sho、Tatsumi Toshifumi、Kaneko Yudai、Kawamura Takeshi、Miura Mai、Ishii Masazumi、Ohkubo Kei、Osawa Tsuyoshi、Kodama Tatsuhiko、Ishikawa Shumpei、Kanai Motomu、Sugiyama Akira
- Journal Title
  
  Protein Expression and Purification
  
  Volume: 192 Pages: 106043-106043
- DOI
  10.1016/j.pep.2021.106043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03510, KAKENHI-PROJECT-21H02779, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-20H02779, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-21K19399, KAKENHI-PUBLICLY-20H04819
[Journal Article] Pathological complete remission of relapsed tumor by photo‐activating antibody-mimetic drug conjugate treatment2022
- Author(s)
  Kaneko Yudai、Yamatsugu Kenzo、Yamashita Takefumi、Takahashi Kazuki、Tanaka Toshiya、Aki Sho、Tatsumi Toshifumi、Kawamura Takeshi、Miura Mai、Ishii Masazumi、Ohkubo Kei、Osawa Tsuyoshi、Kodama Tatsuhiko、Ishikawa Shumpei、Tsukagoshi Masanobu、Chansler Michael、Sugiyama Akira、Kanai Motomu、Katoh Hiroto
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 12 Pages: 4350-4362
- DOI
  10.1111/cas.15565
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05024, KAKENHI-PROJECT-19H01032, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-20H02779, KAKENHI-PROJECT-21H02779, KAKENHI-PROJECT-20K07260, KAKENHI-PROJECT-21K19399, KAKENHI-PUBLICLY-20H04819, KAKENHI-ORGANIZER-22H05017
[Presentation] 胃癌腹膜播種モデルマウスを用いた腹膜播種に対するAt-211標識抗FGFR4抗体による放射線免疫療法の検討2024
- Author(s)
  ４、久下恒明、杜婉瑩、増田寛喜、保田智彦、杉山暁、巽俊文、羽場宏光、瀬戸泰之、吉田寛、秋光信佳、熊倉嘉貴、和田洋一郎、野村幸世
- Organizer
  第96回日本胃癌学会総会
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] 胃癌腹膜播種モデルマウスを用いた211At標識抗FGFR4抗体による放射線免疫療法の有効性2023
- Author(s)
  久下恒明、増田寛喜杜婉瑩保田智彦杉山暁羽場宏光巽俊文秋光信佳熊倉嘉貴吉田寛瀬戸泰之和田洋一郎野村幸世
- Organizer
  第78回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] タウタンパク質の凝集への塩添加効果2023
- Author(s)
  高橋知未、山根大典、巽理紗、堀由起子、富田泰輔、栗田玲
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-23KK0133
[Presentation] Pretargeted alpha radioimmunotherapy for the treatment of gastric cancer using low-immunogenic mutated streptavidin and 211At labeled modified bis-iminobiotin2023
- Author(s)
  Kohshin Washiyama, Toshifumi Tatsumi, Akira Sugiyama, Songji Zhao, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  12th International Symposium on Targeted Alpha Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] Antibody Mimetic Drug Conjugateによるがん治療法開発2023
- Author(s)
  坂田樹理、巽俊文、金井求、児玉龍彦、徳山英利、山次健三、杉山暁
- Organizer
  日本抗体学会
- Data Source
  KAKENHI-PROJECT-21H02779
[Presentation] RADIOIMMUNOTHERAPY OF AT-211-LABELED ANTI-FIBROBLAST GROWTH FACTOR RECEPTOR 4 (FGFR4) ANTIBODY IS A PROMISING TREATMENT FOR PERITONEAL DISSEMINATION OF GASTRIC CANCER: IN IMMUNOCOMPETENT MICE STUDY2023
- Author(s)
  Komei Kuge, Hiroki Masuda,, Wan-Ying Du, Tomohiko Yasuda, Akira Sugiyama, Hiromitsu Haba, Toshifumi Tatsumi, Nobuyoshi Akimitsu, Yoshitaka Kumakura, Hiroshi Yoshida, Yasuyuki Seto, Youichiro Wada, Sachiyo Nomura
- Organizer
  DDW2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] 胃癌腹膜播種モデルマウスを用いた腹膜播種に対するAt-211標識抗FGFR4抗体による放射線免疫療法の検討2023
- Author(s)
  久下恒明、増田寛喜、杜婉瑩、保田智彦、杉山暁、巽俊文、羽場宏光、熊倉嘉貴、瀬戸泰之、吉田寛、秋光信佳、和田洋一郎、野村幸世
- Organizer
  第34回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] がん治療にα線をどう使うか：α線治療薬2022
- Author(s)
  久下恒明、杜婉瑩、保田智彦、杉山暁、羽場宏光、巽俊文、秋光信佳、熊倉嘉貴、吉田寛、瀬戸泰之、和田洋一郎、野村幸世
- Organizer
  第81回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] 胃癌腹膜播種モデルマウスを用いた腹膜播種に対する211At標識抗FGFR4抗体による放射線免疫療法2022
- Author(s)
  久下恒明、杜　婉瑩、杉山暁、巽俊文、羽場宏光、秋光信佳、熊倉嘉貴、和田洋一郎、野村幸世　他
- Organizer
  第33回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] 胃癌腹膜播種モデルマウスを用いた　211At標識抗FGFR4抗体による　放射線免疫療法の検討2022
- Author(s)
  久下恒明、杉山暁，羽場宏光，巽俊文、熊倉嘉貴、和田洋一郎，野村幸世　他
- Organizer
  第66回日本放射化学討論会
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] 胃癌腹膜播種モデルマウスを用いた腹膜播種に対する211At標識抗FGFR4抗体による放射線免疫療法の検討2022
- Author(s)
  久下恒明、杜婉瑩、保田智彦、杉山暁、羽場宏光、巽俊文、秋光信佳、熊倉嘉貴、吉田寛、瀬戸泰之、和田洋一郎、野村幸
- Organizer
  第81回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] Synthesis of an 211At labelled bis-iminobiotin derivativewith enhanced plasma stability2022
- Author(s)
  Kohshin Washiyama, Toshifumi Tatsumi, Akira Sugiyama, Songji Zhao, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  2022 JSNM Annual Meeting
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 改変ストレプトアビジン-イミノビオチンを用いた抗体ミメティクス薬物複合体と近赤外治療法への展開2022
- Author(s)
  山次健三、高橋和希、加藤洋人、山下雄史、安藝翔、巽俊文、金子雄大、川村猛、三浦麻衣、石井正純、大久保敬、大澤毅、児玉龍彦、石川俊平、杉山暁、金井求
- Organizer
  第39回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-21H02779
[Presentation] 低免疫原性ストレプトアビジン変異体と改変ビオチンを用いるプレターゲティングシステムの開発2022
- Author(s)
  巽俊文、鷲山幸信、金井求他
- Organizer
  日本放射化学会第66回討論会
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] 改変ストレプトアビジン－イミノビオチンを用いた抗体ミメティクス薬物複合体と近赤外治療法への展開2022
- Author(s)
  山次健三、高橋和希、加藤洋人、山下雄史、安藝翔、巽俊文、金子雄大、川村猛、三浦麻衣、石井正純、大久保敬、大澤毅、児玉龍彦、石川俊平、杉山暁、金井求
- Organizer
  日本ケミカルバイオロジー学会第16回年会
- Data Source
  KAKENHI-PROJECT-21H02779
[Presentation] Synthesis and evaluation of 211At-labeled bis-iminobiotin for pretargeted alpha radioimmunotherapy2022
- Author(s)
  Kohshin Washiyama, Toshifumi Tatsumi, Akira Sugiyama, Songji Zhao, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  2022 SNMMI Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 改変ストレプトアビジン―イミノビオチン薬物送達システムを用いた近赤外治療法の開発(Near-infrared Phototherapy Using Modified Streptavidin-iminobiotin drug delivery system.)2022
- Author(s)
  山次健三, 加藤洋人, 山下雄史,安藝翔3, 巽俊文, 高橋和希, 金子雄大, 三浦麻衣, 石井正純, 大久保　敬, 大澤毅, 児玉龍彦, 石川俊平, 金井求, 杉山暁
- Organizer
  日本薬学会第142回年会
- Data Source
  KAKENHI-PROJECT-21H02779
[Presentation] 胃癌腹膜播種モデルマウスを用いた腹膜播種に対する211At標識抗FGFR4抗体による放射線免疫療法2022
- Author(s)
  久下恒明、杜　婉瑩、増田寛喜、保田智彦、杉山暁、巽俊文、羽場宏光、瀬戸泰之、吉田寛、秋光信佳、熊倉嘉貴、和田洋一郎、野村幸世
- Organizer
  第33回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] Targeted delivery of 211At with low immunogenic mutant streptavidin-bisiminobiotin pre-targeting system2021
- Author(s)
  Toshifumi Tatsumi, Kenzo Yamatsugu, Akira Sugiyama, Songji Zhao, Miho Aok, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Chengbo Tan, Fengying Gao, Taiki Joho, Noboru Oriuchi, Kazuhiro Takahash, Motomu Kanai, Tatsuhiko Kodama, Kohshin Washiyama
- Organizer
  The 2021 International Chemical Congress of Pacific Basin Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] Targeted delivery of 211-At with low immunogenic mutant streptavidin-bisiminobiotin pre-targeting therapy2021
- Author(s)
  Toshifumi Tatsumi, Kenzo Yamatsugu, Yohei Shimizu, Akira Sugiyama, Songji Zhao, Ken-ichi Nishijima, Naoyuki Ukon, Noboru Oriuchi, Kazuhiro Takahashi, Kohshin Washiyama, Tatsuhiko Kodama,Motomu Kanai
- Organizer
  AIMECS 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02779
[Presentation] Targeted delivery of 211-At with low immunogenic mutant streptavidin-bisiminobiotin pre-targeting therapy2021
- Author(s)
  Toshifumi Tatsumi, Kenzo Yamatsugu, Yohei Shimizu, Akira Sugiyama, Songji Zhao, Ken-ichi Nishijima, Naoyuki Ukon, Noboru Oriuchi, Kazuhiro Takahashi,Kohshin Washiyama, Tatsuhiko Kodama, Motomu Kanai
- Organizer
  AIMECS 2021: 13th AFMC INTERNATIONAL MEDICINAL CHEMISTRY SYMPOSIUM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] Targeted delivery of At-211 with low immunogenic mutant streptavidin-bisiminobiotin pre-targeting system2021
- Author(s)
  Toshifumi Tatsumi, Kenzo Yamatsugu, Akira Sugiyama, Songji Zhao, Miho Aoki, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Chengbo Tan, Fengying Gao, Taiki Joho, Noboru Oriuchi, Kazuhiro Takahashi, Motomu Kanai, Tatsuhiko Kodama, Kohshin Washiyama
- Organizer
  Pacifichem 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02779
[Presentation] Targeted delivery of 211At with low immunogenic mutant streptavidin-bisiminobiotin pre-targeting system2021
- Author(s)
  Toshifumi Tatsumi, Kenzo Yamatsugu, Akira Sugiyama, Songji Zhao, Miho Aoki, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Chengbo Tan, Fengying Gao, Taiki Joho, Noboru Oriuchi, Kazuhiro Takahashi, Motomu Kanai, Tatsuhiko Kodama, Kohshin Washiyama
- Organizer
  The 2021 International Chemical Congress of Pacific Basin Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] イミノビオチン誘導体の合成とアスタチン標識の検討2020
- Author(s)
  粟生木美穂, 巽俊文, 西嶋剣一, 山次健三, 城寶大輝, 趙松吉, 杉山暁, 児玉龍彦, 高橋和弘, 金井求, 鷲山幸信
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] プレターゲティングへの応用を目指した211At標識改変イミノビオチンの体内分布測定2020
- Author(s)
  鷲山幸信, 巽俊文, 杉山暁, 粟生木美穂, 譚成博, 下山彩希, 山次健三, 金井求, 児玉龍彦, 趙松吉, 高橋和弘
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 進行癌におけるCupidと211At標識Psyche-Bを用いたプレターゲティング法の治療効果評価2020
- Author(s)
  趙松吉, 右近直之, 織内昇, 高峰英, 下山彩希, 高橋和弘, 巽俊文, 山次健三, 金井求, 杉山暁, 児玉龍彦
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 低免疫原性を持つストレプトアビジンとRI標識イミノビオチンを用いたプレターゲティング法の開発2020
- Author(s)
  杉山暁・山次健三・巽俊文・鷲山幸信・金井求・児玉龍彦・清水洋平・溝端栄一・井上豪
- Organizer
  第60回日本核医学会学術総会,
- Data Source
  KAKENHI-PROJECT-20KK0174
[Presentation] Development of a pre-targeting strategy of low-immunogenic mutated streptavidin with 211At labeled modified biotin for advanced cancer treatment2020
- Author(s)
  Kohshin Washiyama, Akira Sugiyama, Songji Zhao, Toshifumi Tatsumi, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Chengbo Tan, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  SNMMI 2020 Annual Meeting - Virtual Edition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] Search for the optimal bis-iminobiotin for the pretargeting strategy using a mutated low immunogenic streptavidin2020
- Author(s)
  K. Washiyama, T. Tatsumi, S. Zhao, A. Sugiyama, M. Aoki, K. Yamatsugu, N. Ukon, K. Nishijima, S. Shimoyama, C. Tan, T. Joho, N. Oriuchi, M. Kanai, K. Takahashi, T. Kodama
- Organizer
  33th Annual Congress of the European Association of Nuclear Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 211At標識イミノビオチンを用いたプリターゲティング法の最適化投与間隔による薬物動態評価2020
- Author(s)
  右近直之, 鷲山幸信, 杉山暁, 巽俊文, 山次健三, 下山彩希, 織内昇, 金井求, 児玉龍彦, 高橋和弘, 趙松吉
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] Biodistribution and dosimetry studies for the optimization of pre-targeted radionuclide therapy using 211At-labeled modified biotin2020
- Author(s)
  Kohshin Washiyama, Akira Sugiyama, Songji Zhao, Toshifumi Tatsumi, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  33th Annual Congress of the European Association of Nuclear Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 低免疫原性を持つストレプトアビジンとRI標識イミノビオチンを用いたプレターゲティング法の開発2020
- Author(s)
  杉山暁、山次健三、巽俊文、鷲山幸信、金井求、児玉龍彦、清水洋平、溝端栄一、井上豪
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] α放射体211At標識イミノビオチンの作成と安定性評価2020
- Author(s)
  鷲山幸信、粟生木美穂、巽俊文、山次健三、杉山暁、西嶋剣一、城寶大輝、高峰英、趙松吉、金井求、児玉龍彦、高橋和弘
- Organizer
  日本放射化学会第64回討論会(2020)
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 進行がん治療を指向した低免疫原性ストレプトアビジン変異体と 211At標識イミノビオチンを用いるプレターゲティングシステムの開発2020
- Author(s)
  巽俊文, 山次健三, 清水洋平, 杉山暁, 趙松吉, 粟生木美穂, 西嶋剣一, 右近直之, 高橋和弘, 児玉龍彦, 鷲山幸信, 金井求
- Organizer
  反応と合成の進歩2020特別企画シンポジウム|
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] α放射体211Atを用いたプレターゲティング法による進行がんの治療2020
- Author(s)
  Kohshin Washiyama, Akira Sugiyama, Kenzo Yamatsugu, Songji Zhao, Toshifumi Tatsumi, Miho Aoki, Naoyuki Ukon, Saki Shimoyama, Ken-ichi Nishijima, Chengbo Tan, Taiki Joho, Fengying Gao, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
- Organizer
  日本放射線影響学会第63回大会
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] Evaluation of therapeutic effect of the targeted alpha therapy using Cupid-211At-labeled Psyche-B pretargeting system in a human gastric cancer cell xenograft2020
- Author(s)
  Songji Zhao, Akira Sugiyama, Naoyuki Ukon, Saki Shimoyama, Toshifumi Tatsumi, Miho Aoki, Fengying Gao, Kenzo Yamatsugu, Ken-ichi Nishijima, Taiki Joho, Noboru Oriuchi, Kazuhiro Takahashi, Motomu Kanai, Tatsuhiko Kodama, Kohshin Washiyama
- Organizer
  33th Annual Congress of the European Association of Nuclear Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03627
[Presentation] 進行がん治療を指向した低免疫原性ストレプトアビジン変異体と211At 標識イミノビオチンを用いるプレターゲティングシステムの開発2020
- Author(s)
  巽俊文・山次健三・清水洋平・杉山暁・趙松吉・粟生木美穂・西嶋剣一・右近直之・高橋和弘・児玉龍彦・鷲山幸信・金井求
- Organizer
  反応と合成の進歩2020特別企画シンポジウム
- Data Source
  KAKENHI-PROJECT-20KK0174

1. Sugiyama Akira (40562715)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. Wada Yuichiro (10322033)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. 野村幸世 (70301819)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 熊倉嘉貴 (90517773)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. Washiyama Kohshin (80313675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
6. 桧垣正吾 (50444097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 高橋和弘 (20370257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
8. 山下雄史 (50615622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 右近直之 (70792985)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
10. 横山明彦 (80230655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 趙松吉 (80374239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
12. 粟生木美穂 (10783227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
13. 田中十志也 (20396930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 坂田樹理 (20772700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 秋光信佳 (40294962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 羽場宏光 (60360624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 富田泰輔 (30292957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 金井求 (20243264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 堀由起子 (80610683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. マラフスカカタジナ・ヨアンナ (90986374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 上ノ町水紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tatsumi Toshifumi 巽 俊文

Research Projects

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Co-Researchers

Development of Cearing Agent to Innovate the Pre-targeting TherapyPrincipal Investigator

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α線放出核種と抗体ドラッグデリバリーシステムによる新規放射性医薬品の開発

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Elucidation of the role of autophagy in photo-oxygenated amyloid degradation

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Creation of Next Generation Antibody Drug Conjugate Therapeutics for Advanced Cancer

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Collaborative Therapeutic Isotope Production and Radiopharmaceutical Synthesis

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Optimization of pretargeted alpha therapy for multiple types of cancer

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[Journal Article] pH dependence of perturbed angular correlation in DOTA chelated $$^{111}$$In measured with ring-shape gamma-ray detectors2024

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[Journal Article] Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin2024

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[Journal Article] Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system2022

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[Journal Article] Pathological complete remission of relapsed tumor by photo‐activating antibody-mimetic drug conjugate treatment2022

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[Presentation] 胃癌腹膜播種モデルマウスを用いた腹膜播種に対するAt-211標識抗FGFR4抗体による 放射線免疫療法の検討2024

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[Presentation] 胃癌腹膜播種モデルマウスを用いた211At標識抗FGFR4抗体による放射線免疫療法の有効性2023

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[Presentation] タウタンパク質の凝集への塩添加効果2023

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[Presentation] Pretargeted alpha radioimmunotherapy for the treatment of gastric cancer using low-immunogenic mutated streptavidin and 211At labeled modified bis-iminobiotin2023

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[Presentation] Antibody Mimetic Drug Conjugateによるがん治療法開発2023

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Tatsumi Toshifumi 巽俊文

[Presentation] 胃癌腹膜播種モデルマウスを用いた腹膜播種に対するAt-211標識抗FGFR4抗体による放射線免疫療法の検討2024

[Presentation] 胃癌腹膜播種モデルマウスを用いた　211At標識抗FGFR4抗体による　放射線免疫療法の検討2022