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TSUKAMOTO Toshiyuki  塚本 俊彦

ORCIDConnect your ORCID iD *help
Researcher Number 10236862
Affiliation (based on the past Project Information) *help 1996 – 2005: 北里大学, 薬学部, 助教授
2002: 山梨大学, 薬学部, 助教授
1995: 自治医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Biological Sciences / Structural biochemistry / Applied genomics / Digestive surgery
Except Principal Investigator
Digestive surgery / Human pathology / Virology / 免疫の制御機構
Keywords
Principal Investigator
大腸癌 / 突然変異 / Transcription / RNA polymerase II / RNA processing / mRNA cap structure / mRNA cap methyltransferase / mRNA capping enzyme / 転写 / RNAポリメラーゼII … More / RNAプロセシング / mRNAキャップ構造 / mRNAキャップメチルトランスフェラーゼ / mRNAキャッピング酵素 / Mutation / クローニング / キャッピング酵素 / キャップ構造 / mRNA / RNA editing / エピトープライブラリー / 腫瘍マーカー … More
Except Principal Investigator
Cyclin / EGFR / Japanese clinical criteria / aberrant crypt foci / K ras / Chk / Fyn / Pyk2 / チロシンキナーゼ / Cdk / Lung carcinoma / Apoptosis / Cell cycle / Soft tissue tumors / AMF / cdk抑制因子 / アポトーシス / 細胞周期 / 肺癌 / 骨軟部肉腫 / BRAF / hMLH1 methylation / hMSH2 / hMLH1 / Hereditary nonpolyposis colorectal carcinoma (HNPCC) / Mismatch repair genes / E.coli Muts / 大腸菌Mut S蛋白 / マイクロサテライト不安定性 / Japan clinical criteria / HNPCC / BRAF遺伝子 / hMLH1メチル化 / hMSH2遺伝子 / hMLH1遺伝子 / 遺伝性非ポリポーシス大腸癌(HNPCC) / ミスマッチ修復遺伝子 / 大腸菌MutS蛋白 / colonoscopy / hyperplastic polyp / adenoma / 大腸癌 / 拡大内視鏡 / 鋸歯状腺種 / 大腸腺種 / K-ras / 大腸内視鏡検査 / 過形成性ポリープ / 大腸腺腫 / aderrant crypt foci / tubulin / mRNA cap / transcription / host factor / RNA-dependent RNA polymerase / negative-strand RNA genome / Sendai virus / Paramyxovirus / in vitro転写反応 / パラミクソウイルス科 / パラミフソウイルス / mRNAキャッピング / ウイルスmRNA / マイナス鎮RNAゲノム / ウイルスLタンパク質 / キャップメチル化酵素 / mRNAキャップ構造 / ウイルスmRNA合成 / チューブリン / mRNAキャップ / 転写 / 宿主因子 / RNA依存RNAポリメラーゼ / マイナス鎖RNAゲノム / センダイウイルス / パラミクソウイルス / AIDS / Salmonella / Infection Immunity / Isoform / Tyrosine Kinase / マクロファージ分化 / エイズ / サルモネラ / 感染免疫 / アイソフォーム / レチノイン酸(retinoic acid) / 抗生物質(antibiotics) / adhesion(接着) / apoptosis(アポトーシス) / Leukemia(白血病) Less
  • Research Projects

    (13 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (15 People)
  •  DNA修復酵素を用いた突然変異特異的クローニング法の確立Principal Investigator

    • Principal Investigator
      塚本 俊彦
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kitasato University
  •  Development of a novel strategy for mutation-specific cloning using DNA repair enzymePrincipal Investigator

    • Principal Investigator
      TSUKAMOTO Toshihiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied genomics
    • Research Institution
      Kitasato University
  •  DNA修復酵素を用いた突然変異特異的クローニング法の確立Principal Investigator

    • Principal Investigator
      塚本 俊彦
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kitasato University
  •  DNA修復酵素を用いた突然変異特異的クローニング法の確立Principal Investigator

    • Principal Investigator
      塚本 俊彦
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kitasato University
  •  Analyses for abnormality of cell cycle regulator molecules and their application to diagnosis and therapy in bone and soft tissue tumors

    • Principal Investigator
      DOBASHI Yoh
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      University of Yamanashi
      山梨医科大学
  •  Prevalence and Molecular Biological Feature of Human Aberrant Crypt Foci

    • Principal Investigator
      TOGASHI Kazutomo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      JICHI MEDICAL SCHOOL
  •  A new method for detection of gene mutations using both E.coli MutS protein and resolvase

    • Principal Investigator
      SHITOH Kazuhisa, 小島 正幸
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      JICHI MEDICAL SCHOOL
  •  Structure and function of mRNA capping enzyme systemPrincipal Investigator

    • Principal Investigator
      TSUKAMOTO Toshihiko
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kitasato University
  •  Mechanism of transcription of Paramyxovirus genome : Purification and characterization of host factors

    • Principal Investigator
      MIZUMOTO Kiyohisa
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Kitasato University
  •  Structure and function of mRNA capping enzymePrincipal Investigator

    • Principal Investigator
      TSUKAMOTO Toshihiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kitasato University
  •  Role of Tyrosine Kinase in Infection Immunity

    • Principal Investigator
      MORIKAWA Yuko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      免疫の制御機構
    • Research Institution
      The Kitasato Institute
  •  白血病細胞のアポトーシス誘導ならびに浸潤阻止のための制御技術と天然薬物の開発

    • Principal Investigator
      KATAGIRI Takuya
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kitasato Institute
  •  エピトープライブラリーを使用した大腸癌腫瘍マーカーの開発Principal Investigator

    • Principal Investigator
      塚本 俊彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Jichi Medical University

All Other

All Journal Article

  • [Journal Article] Clinicopathological characteristics of colorectal cancers with loss of imprinting of insulin-like growth factor 2.

    • Author(s)
      Sasaki, J., Konishi, F., Kawamura, Y, Kai., T., Takata, O., Tsukamoto, T.
    • Journal Title

      Int J Cancer In press

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16510149
  • [Journal Article] The majority of human aberrant crypt foci in the lower rectum are precursors of hyperplastic polyps.

    • Author(s)
      Togashi, K., Konishi, F., Kojima, M., Nagai, H., Tsukamoto, T.
    • Journal Title

      Dis Colon Rec (In press)

    • Data Source
      KAKENHI-PROJECT-16510149
  • [Journal Article] Overexpression in colorectal cancer of two lysosomal enzymes, CLN2 and CLN1, involved in neuronal ceroid lipofuscinosis.

    • Author(s)
      Tsukamoto, T., Iida, J., Dobashi, Y., Furukawa, T., Konishi, F.
    • Journal Title

      Cancer In press

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16510149
  • [Journal Article] cDNA array analysis for diagnosis of hepatic metastasis of colorectal carcinoma using tissue samples obtained from primary tumors.

    • Author(s)
      Takata, O., Kawamura, Y., Konishi, F., Sasaki, J., Kai, T., Miyakura, Y., Nagai, H., Tsukamoto, T.
    • Journal Title

      Surgery Today (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16510149
  • [Journal Article] The majority of human aberrant crypt foci in the lower rectum are precursors of hyperplastic polyps.

    • Author(s)
      Togashi, K., Konishi, F., Kojima, M., Nagai, H., Tsukamoto, T.
    • Journal Title

      Dis Colon Rec In press

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16510149
  • [Journal Article] cDNA array analysis for diagnosis of hepatic metastasis of colorectal carcinoma using tissue samples obtained from primary tumors.

    • Author(s)
      Takata, O., Kawamura, Y., Konishi, F., Sasaki, J., Kai, T., Miyakura, Y., Nagai, H., Tsukamoto, T.
    • Journal Title

      Surgery Today In press

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16510149
  • [Journal Article] The majority of human aberrant crypt foci in the lower rectum are precursors of hyperplastic polyps.

    • Author(s)
      Togashi, K., Konishi, F., Kojima, M., Nagai, H., Tsukamoto, T.
    • Journal Title

      Dis Colon Rectum (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16510149
  • [Journal Article] Clinicopathological characteristics of colorectal cancers with loss of imprinting of insulin-like growth factor 2.

    • Author(s)
      Sasaki, J., Konishi, F., Kawamura, Y., Kai, T., Takata, O., Tsukamoto, T.
    • Journal Title

      Int J Cancer (In press)

    • Data Source
      KAKENHI-PROJECT-16510149
  • [Journal Article] Overexpression in colorectal cancer of two lysosomal enzymes, CLN2 and CLN1, involved in neuronal ceroid lipofuscinosis.

    • Author(s)
      Tsukamoto, T., Iida, J., Dobashi, Y., Furukawa, T., Konishi, F.
    • Journal Title

      Cancer (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16510149
  • [Journal Article] Overexpression in colorectal cancer of two lysosomal enzymes, CLN2 and CLN1, involved in neuronal ceroid lipofuscinosis.

    • Author(s)
      Tsukamoto, T., Iida, J., Dobashi, Y., Furukawa, T., Konishi, F.
    • Journal Title

      Cancer (In press)

    • Data Source
      KAKENHI-PROJECT-16510149
  • [Journal Article] cDNA array analysis for diagnosis of hepatic metastasis of colorectal carcinoma using tissue samples obtained from primary tumors.

    • Author(s)
      Takata, O., Kawamura, Y., Konishi, F., Sasaki, J., Kai, T., Miyakura, Y., Nagai, H., Tsukamoto, T.
    • Journal Title

      Surgery Today (In press)

    • Data Source
      KAKENHI-PROJECT-16510149
  • [Journal Article] Clinicopathological characteristics of colorectal cancers with loss of imprinting of insulin-like growth factor 2.

    • Author(s)
      Sasaki, J., Konishi, F., Kawamura, Y, Kai., T., Takata, O., Tsukamoto, T.
    • Journal Title

      Int J Cancer. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16510149
  • 1.  MIZUMOTO Kiyohisa (80092344)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  KATAGIRI Takuya (70126100)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  SHITOH Kazuhisa (90285792)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  林 正彦 (20164965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  供田 洋 (70164043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MORIKAWA Yuko (20191017)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  DANBARA Hirofumi (40114558)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MATSUI Hidenori (30219373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KIKUCHI Yuji (60262078)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OGINO Tomoaki (80312213)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  IWAMA Minako (10223421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TOGASHI Kazutomo (10316531)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  SATO Tomoyuki (50225976)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  小島 正幸 (00316530)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  DOBASHI Yoh (90231456)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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