HOTOKEZAKA Yuka 佛坂由可

… Alternative Names

光田由可

Less

Researcher Number	10244089
Other IDs
Affiliation (Current)	2025: 長崎大学, 病院(歯学系), 講師
Affiliation (based on the past Project Information) *help	2014 – 2024: 長崎大学, 病院(歯学系), 講師 2009 – 2013: 長崎大学, 大学病院, 講師 2012: 長崎大学, 病院, 講師 2010 – 2011: 長崎大学, 長崎大学病院, 講師 2010: 長崎大学, 病院, 講師 … More 2006 – 2008: Nagasaki University, Hospital of Medicine and Dentistry, Assistant Professor, 医学部・歯学部附属病院, 講師 2003 – 2006: 長崎大学, 医学部・歯学部附属病院, 助手 2004: 長崎大学, 大学院・医歯薬学総合研究科, 助手 1995 – 1997: 長崎大学, 歯学部, 助手 Less
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology / Basic Section 57070:Developmental dentistry-related / Basic Section 57060:Surgical dentistry-related / 咀嚼 / 病態科学系歯学(含放射線系歯学) Except Principal Investigator Pathobiological dentistry/Dental radiology / Basic Section 57060:Surgical dentistry-related / Basic Section 57070:Developmental dentistry-related / 病態科学系歯学(含放射線系歯学)
Keywords	Principal Investigator ER stress / 細胞死 / αNAC / hypoxia / HIF-1α / 低酸素 / cPLA2 / siRNA / アポトーシス / apoptosis … More / QCT / γ-taxilin / リボゾーム / 破歯細胞 / GSK3β / 歯根吸収 / 低酸素領域 / 口腔がん / がん治療 / ノックアウト　マウス / HIF-1 / がんの進展 / cpla2 / がん / UV / ribosome / p54^<nrb> / repair DNA / ionizing radiation / p28^<nrp> / p54^<nrb>蛋白質 / 白血病細胞 / DNA障害 / 電離放射線 / p28^<nrp>蛋白質 / Bone mineral density / mandible / 骨密度 / 下顎骨 / MUC1 / cleaved alpha NAC / alpha NAC / DNA障害修復 / アルツハイマー病 / Alzheimer’s diseases / hyoxia / p35 protein / Hypoxia / p21 / 細胞死(アポトーシス) / 放射線 … More Except Principal Investigator cPLA2 / MRI / FEN1 / 歯の移動 / 歯根吸収 / Tip60 / HIF-1α / 矯正歯科治療 / 拡散強調MRI / 細胞質型ホスホリパーゼA2 / PPARγ / atherosclerosis / 電離放射線 / 細胞死 / ADC / p53 / 細胞老化 / ストレス応答 / マイクロRNA / 紫外線 / 拡散強調撮像 / アセチル化 / DNA障害 / 低酸素細胞 / 放射線抵抗性 / ATM / 低酸素 / 細胞小器官 / 破歯細胞 / 拡散強調撮MRI / MRONJ / ARONJ / 骨吸収薬剤関連顎骨壊死 / ダイナミック造影MRI / 骨吸収抑制薬剤関連顎骨壊死 / 矯正力 / HIF-1 / 矯正 / hif-1a / 細胞死シグナル / 細胞生存シグナル / 制限拡散 / 細胞内拡散 / 骨代謝 / 分子イメージング / 骨代謝異常 / 破骨細胞 / odontology / radiology / signaling passway / histology and cell biology / regenerative medicine / 歯学 / 放射線 / シグナル伝達 / 細胞・組織 / 再生医学 / UV / DNA damage / acetylation / macrophage / ionizing radiation / atheroselerosis / マクロファージ / gender / age / spine / quantitative computed tomography / bone mineral density / mandibular condyle / ホルモン / 咬合力 / 下顎骨 / 骨髄 / 性差 / 年齢 / 脊椎 / 定量CT / 骨密度 / 下顎顎関節突起 / fat deposition / salivary gland / Sjogren's syndrome / 診断基準 / テクスチャー解析 / MR / 脂肪変性 / 唾液腺 / Sjogren症候群 / tau / シェーグレン / ＦＤＧ / ＰＥＴ／ＣＴ / FDG-PET / リンパ節転移 / ＭＲＩ / 転移リンパ節 / ＦＤＧ－ＰＥＴ / SUV / 拡散係数 / SDL仮説 / 糖タンパク / 糖蛋白 / 細胞膜 / GAP結合 / MUC1 / knock-outマウス / ｃPLA2 / 非アポトーシス / アポトーシス / リンパ節転移節外進展 / HYPOXIA / 口腔扁平上皮癌患 / 細胞壊死 / 細胞浮腫 / hypoxia / マイクロＲＮＡ / cPLA2α / ギャップ結合 / 細胞間情報交換 / DNA切断 / 老化促進 / 細胞周期 / DAN切断 / テロメア / P53 / 腫瘍 / マウスモデル / XBP=1 / ERストレス / IQIマウス / 自己免疫疾患 / H2AX / cPLA_2 / メカニズム / 癌 / 転移 / リンパ節 / 骨粗鬆症 / 脱毛 / トランスジェニックマウス / 老化 / FEN-1 Less

GSK3β阻害による歯根吸収抑制機構の解明－細胞死と破歯細胞活性を標的にして－Principal Investigator
- Principal Investigator
  
  佛坂由可
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Nagasaki University
歯根吸収発症における細胞小器官分解システム関連蛋白の役割
- Principal Investigator
  
  佛坂斉祉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Nagasaki University
低酸素細胞の放射線抵抗性におけるcPLA2の働き
- Principal Investigator
  
  片山郁夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
口腔がんの進展・転移における低酸素環境下でのcPLA2の働きPrincipal Investigator
- Principal Investigator
  
  佛坂由可
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
Role of cPLA2 in Inhibition of Root Resorption - Targeting hyalinization and Odontoclast Activity
- Principal Investigator
  
  Hotokezaka Hitoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Nagasaki University
The role of MRI on the diagnosis of anti-resorptive agents-related osteonecrosis of the jaw
- Principal Investigator
  
  佐々木美穂
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
The role of cPLA2 activated by irradiation
- Principal Investigator
  
  KATAYAMA Ikuo
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
inhibition of orthodontically induced root resorption by HIF-1a inhibition
- Principal Investigator
  
  Hashimoto Megumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Nagasaki University
Estimation of the sub-cellular diffusion using multi-exponential fitting model
- Principal Investigator
  
  SASAKI Miho
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
the function of cPLA2 in progress and metastasis of tumorPrincipal Investigator
- Principal Investigator
  
  HOTOKEZAKA Yuka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Bone metabolism disorders of cPLA2 knockout mice
- Principal Investigator
  
  KATAYAMA Ikuo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
An analysis of the characteristics of SUV uptakes of the metastatic lymph nodes
- Principal Investigator
  
  SASAKI Miho
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
The role of tau protein in the pathogenesis of salivary gland of SS patients
- Principal Investigator
  
  NAKAMURA Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
dual-function stress response proteinPrincipal Investigator
- Principal Investigator
  
  HOTOKEZAKA Yuka
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
The fate of cells dependent on p53 and FEN1
- Principal Investigator
  
  KATAYAMA Ikuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Role of MUC1 regulated by stress-responsed micro RNA
- Principal Investigator
  
  TASHIRO Shigeki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Glycoprotein of intact plasma membrane determines the diffusion properties of cellular water
- Principal Investigator
  
  EIDA Sato
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Involvement of cPLA2 in apoptotic and non-apoptotic cell death
- Principal Investigator
  
  NAKAMURA Takashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Eftective detection of extranodal spread-positive squamous cellcarcinoma nodes using hypoxia tracer
- Principal Investigator
  
  NAKAMURA Takashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Micro RNA for stress response in cell- cell communication
- Principal Investigator
  
  TASHIRO Shigeki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
ER stress pathway in apoptosis of DNA damagePrincipal Investigator
- Principal Investigator
  
  HOTOKEZAKA Yuka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
The elucidation of the aging promotion mechanism by FEN1 control
- Principal Investigator
  
  KATAYAMA Ikuo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Hypoxia diagnosis by MR spectroscopy and Diffusion Weighted Imaging
- Principal Investigator
  
  EIDA Sato
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
FEN1-related senescence
- Principal Investigator
  
  NAKAMURA Takashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Autoimmune Disease of FEN1 Transgenic Mouse
- Principal Investigator
  
  KIMURA Yasuo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Tip60 acetyltransferase in DNA damage response
- Principal Investigator
  
  TASHIRO Shigeki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Identification of a noble ER stress pathway in hypoxiaPrincipal Investigator
- Principal Investigator
  
  HOTOKEZAKA Yuka
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Is FEN1 involved in the anti-ageing machinery?
- Principal Investigator
  
  NAKAMURA Takashi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
リンパ節転移のWhen,Where,How
- Principal Investigator
  
  中村卓
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
A role of cPLA_2 in the process when extraction socket is repaired.
- Principal Investigator
  
  SUMI Tadateru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
A novel apoptotic pathway dependent on ribosomePrincipal Investigator
- Principal Investigator
  
  HOTOKEZAKA Yuka
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Graduate School of Biomedical Sciences
- Principal Investigator
  
  TASHIRO Shigeki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki university
Investigation of mechanism on radiation-induced atheroma
- Principal Investigator
  
  KATAYAMA Ikuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  NAGASAKI UNIVERSITY
Role of novel protein (p28^<nrp>) induced by ionizing radiationPrincipal Investigator
- Principal Investigator
  
  HOTOKEZAKA Yuka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  NAGASAKI UNIVERSITY
Mandibular condyle bone mineral density measurement by quantitative computed tomography
- Principal Investigator
  
  NAKAMURA Takashi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nagasaki University
放射線による細胞死(アポトーシス)におけるp21遺伝子の役割Principal Investigator
- Principal Investigator
  
  佛坂由可
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nagasaki University
Relaction ship btween occlusion function and bone mineral density of the mancibular condylePrincipal Investigator
- Principal Investigator
  
  HOTOKEZAKA Yuka, 山田美穂
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  咀嚼
- Research Institution
  Nagasaki University
Diagnostic accuracy of digitized dental radiographs
- Principal Investigator
  
  NAKAMURA Takashi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Nagasaki University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] A case of periosteal fasciitis located in the mandible in a child2021
- Author(s)
  Eida Sato、Hotokezaka Yuka、Sasaki Miho、Hotokezaka Hitoshi、Fujita Shuichi、Katayama Ikuo、Takagi Yukinori、Sumi Misa
- Journal Title
  
  Oral Radiology
  
  Volume: 38 Issue: 1 Pages: 175-181
- DOI
  10.1007/s11282-021-00544-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10316, KAKENHI-PROJECT-21K10141
[Journal Article] An approach to estimate the subcellular water diffusivity using high b-value diffusion-weighted magnetic resonance imaging with multiexponential fitting algorithms2021
- Author(s)
  Miho Sasaki, Yuka Hotokezaka, Nobuyuki Inadomi, Ikuo Katayama, Sato Eida, Yukinori Takagi, Misa Sumi
- Journal Title
  
  Oral Science International
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K10144
[Journal Article] Traumatic myositis ossificans: multifocal lesions suggesting malignancy on FDG-PET/CT; a case report2021
- Author(s)
  Miho Sasaki, Yuka Hotokezaka, Reiko Ideguchi, Masataka Uetani, Shuichi Fujita
- Journal Title
  
  Skeletal Radiology
  
  Volume: 50 Issue: 1 Pages: 249-254
- DOI
  10.1007/s00256-020-03521-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10144, KAKENHI-PROJECT-21K10141
[Journal Article] A case of tophaceous pseudogout of the temporomandibular joint extending into the cranium2020
- Author(s)
  Yuka Hotokezaka, Hitoshi Hotokezaka, Ikuo Katayama, Shuichi Fujita, Miho Sasaki, Sato Eida, Masataka Uetani
- Journal Title
  
  Oral Radiology
  
  Volume: 36 Issue: 2 Pages: 203-208
- DOI
  10.1007/s11282-019-00410-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10317
[Journal Article] ATM-associated signalling triggers the unfolded protein response and cell death in response to stress2020
- Author(s)
  Hotokezaka Yuka、Katayama Ikuo、Nakamura Takashi
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 378-378
- DOI
  10.1038/s42003-020-1102-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10317
[Journal Article] Magnetic resonance perfusion and diffusion characteristics of granulomatous disease mimic those of malignant lesions: six case reports2018
- Author(s)
  Sumi Misa, Takagi Yukinori, Sasaki Miho, Eida Sato, Katayama Ikuo, Hotokezaka Yuka, Nakamura Takashi
- Journal Title
  
  Oral Radiology
  
  Volume: 34(1) Issue: 1 Pages: 73-82
- DOI
  10.1007/s11282-017-0271-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11078, KAKENHI-PROJECT-16K11512
[Journal Article] Lithium chloride reduces orthodontically induced root resorption and affects tooth root movement in rats2018
- Author(s)
  Ino-Kondo A, Hotokezaka H, Kondo T, Arizono K, Hashimoto M, Hotokezaka Y, Kurohama T, Morita Y, Yoshida N
- Journal Title
  
  The Angle Orthodontist
  
  Volume: 88 Pages: 474-482
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11511
[Journal Article] Length of intact plasma membrane determines the diffusion properties of cellular water2016
- Author(s)
  Sato Eida, Marc Van Cauteren, Yuka Hotokezaka, Ikuo Katayama, Miho Sasaki, Makoto Obara, Tomoyuki Okuaki, Misa Sumi, Takashi Nakamura
- Journal Title
  
  Scientific Reports
  
  Volume: 6 ;19051 Issue: 1 Pages: 1-10
- DOI
  10.1038/srep19051
- NAID
  120006987227
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462845, KAKENHI-PROJECT-25462921, KAKENHI-PROJECT-25462922, KAKENHI-PROJECT-25462924, KAKENHI-PROJECT-26670819
[Journal Article] GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses.2015
- Author(s)
  Hotokezaka Y, Katayama I, van Leyen K, Nakamura T
- Journal Title
  
  Cell Death and Disese
  
  Volume: 6
- NAID
  120006987615
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462921
[Journal Article] GSK3-β-dependent downregulation of γ-taxillin and αNAC merge to regulate ER stresss responses.2015
- Author(s)
  Hotokezaka Y, Katayama I, van Leyen K, Nakamura T
- Journal Title
  
  Cell Death and Disese
  
  Volume: 6
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462922
[Journal Article] GSK3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses.2015
- Author(s)
  Hotokezaka Y, Katayama I, van Leyen K, Nakamura T
- Journal Title
  
  Cell Death Dis
  
  Volume: 6
- NAID
  120006987615
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670819
[Journal Article] GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses.2015
- Author(s)
  Hotokezaka Y, Katayama I, van Leyen K, Nakamura T.
- Journal Title
  
  Cell Death Dis
  
  Volume: 6 Issue: 4 Pages: e1719-e1719
- DOI
  10.1038/cddis.2015.90
- NAID
  120006987615
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390421, KAKENHI-PROJECT-25462921
[Journal Article] Simple and reliable determination of intravoxel incoherent motion parameters for the differential diagnosis of head and neck tumors.2014
- Author(s)
  Sasaki M, Sumi M, Eida S, Katayama I, Hotokezaka Y, Nakamura T
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 11 Pages: 1-11
- DOI
  10.1371/journal.pone.0112866
- NAID
  120006986329
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592837, KAKENHI-PROJECT-26462845
[Journal Article] Comparison between ultrasonography and MR imaging for discriminating squamous cell carcinoma nodes with extranodal spread in the neck2012
- Author(s)
  Katayama I, Sasaki M, Kimura Y, Hotokezaka Y, Eida S, Tashiro S, Sumi M, Nakamura T
- Journal Title
  
  Eur J Radiol
  
  Volume: 81(11) Pages: 3326-3331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592087
[Journal Article] Apparent diffusion coefficient characterization of the fluid areas in cystic and abscess lesions of the neck2012
- Author(s)
  Ichikawa Y, Sumi M, Eida S, Takagi Y, Tashiro S, Hotokezaka Y, Katayama I, Nakamura T
- Journal Title
  
  Oral Radiol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592087
[Journal Article] Apparent diffusion coefficient-based differentiation of cystic lesions of the mandible2012
- Author(s)
  Eida S, Hotokezaka Y, Katayama I, Ichikawa Y, Tashiro S, Sumi T, Sumi M, Nakamura T
- Journal Title
  
  Oral Radiol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592087
[Journal Article] Comparison between ultrasonography and MR imaging for discriminating squamous cell carcinoma nodes with extranodal spread in the neck.2012
- Author(s)
  Katayama I, Sasaki M, Kimura Y, Hotokezaka Y, Eida S, Tashiro S, Sumi M, Nakamura T
- Journal Title
  
  European Journal of Radiology
  
  Volume: 81 Issue: 11 Pages: 3326-3331
- DOI
  10.1016/j.ejrad.2012.06.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592087, KAKENHI-PROJECT-23659881
[Journal Article] Comparison between ultrasonography and MR imaging for discriminating squamous cell carcinomanodes with extranodal spread in the neck2012
- Author(s)
  Katayama I, Sasaki M, Kimura Y,Hotokezaka Y,Eida S, Tashiro S, Sumi M, Nakamura T
- Journal Title
  
  Eur J Radiol
  
  Volume: 81巻 Pages: 3326-3331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659881
[Journal Article] Apparent diffusion coefficient characterization of the fluid areas in cystic and abscess lesions of the neck.2012
- Author(s)
  Ichikawa Y, Sumi M, Eida S, Takagi Y, Tashiro S, Hotokezaka Y, Katayama I, Nakamura T
- Journal Title
  
  Oral Radiology
  
  Volume: 28 Issue: 1 Pages: 62-69
- DOI
  10.1007/s11282-012-0082-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592087
[Journal Article] Apparent diffusion coefficient-based differentiation of cystic lesions of the mandible.2012
- Author(s)
  Eida S, Hotokezaka Y, Katayama I, Ichikawa Y, Tashiro S, Sumi T, Sumi M, Nakamura T
- Journal Title
  
  Oral Radiology
  
  Volume: 28 Issue: 2 Pages: 109-114
- DOI
  10.1007/s11282-012-0095-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592087
[Journal Article] αNAC depletion as an initiation of ER stress-induced apoptosiinHypoxia.2009
- Author(s)
  Hotokezaka Y, Nakamura T, etc
- Journal Title
  
  Cell Death Differ 16
  
  Pages: 1505-1514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390504
[Journal Article] αNAC depletion as an initiation of ER stress-induced apoptosis in Hypoxia2009
- Author(s)
  佛坂由可、van leyen K、Lo EH、Beatrix B、片山郁夫、Jin G, 中村卓
- Journal Title
  
  Cell Death Differ
  
  Volume: 16(11) Pages: 1505-1514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390504
[Journal Article] Ionizing radiation induces macrophage foam cell formation and Aggregation through JNK-dependent activation of CD36 scavenger Receptors2008
- Author(s)
  Katayama I, Hotokezaka Y Matsuyama T, Sumi T Nakamura T
- Journal Title
  
  Int J Radiat Oncol Boil Phys 70
  
  Pages: 835-846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390500
[Journal Article] Ionizing radiation induces macrophage foam cell formation and aggregation through JNK-dependent activation of CD36 scavenger receptors.2008
- Author(s)
  Katayama I, Hotokezaka Y, Matsuyama T, Sumi T, Nakamura T
- Journal Title
  
  Int J Radiat Oncol Biol Phys 70(3)
  
  Pages: 835-846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390500
[Journal Article] Ionizing radiation induces macrophage foam cell formation and aggregation through JNK-dependent activation of CD36 scavenger receptors2008
- Author(s)
  片山郁夫、佛坂由可、松山俊文、角忠輝、中村卓
- Journal Title
  
  Int J Radiat Oncol Biol Phys 70(3)
  
  Pages: 835-846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390500
[Presentation] Enhanced fixation of orthodontic anchor screws using β-TCP-an experiment using rats.2021
- Author(s)
  Nishioka K, Hotokezaka H, Nashiro Y, Funaki M, Hotokezaka Y, Ohba S, Yoshida N.
- Organizer
  The 80th Annual Meeting of Japanese Orthodontic Society & The 5th International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K10141
[Presentation] Suppression of orthodontic root resorption by lithium and elucidation of its mechanism.2021
- Author(s)
  Ueda Y, Hotokezaka H, Miyazaki T, Moriishi T, Hotokezaka Y, Arizono K, Nakamura T, Yoshida N
- Organizer
  The 80th Annual Meeting of Japanese Orthodontic Society & The 5th International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K10141
[Presentation] Effect of administration of botulinum toxin type A in masseter on tooth movement in rats.2021
- Author(s)
  Ueda Y, Hotokezaka H, Arizono K, Nashiro Y, Morita Y, Hotokezaka Y, Yoshimi T, Yoshimi K, Yoshida N.
- Organizer
  The 80th Annual Meeting of Japanese Orthodontic Society & The 5th International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K10141
[Presentation] Investigation of threshold of narrowing of periodontal ligament space causing root resorption by orthodontic force.2021
- Author(s)
  Nakamura T, Hotokezaka H, Hotokezaka Y, Ueda Y, Nishioka K, Nashiro Y, Yoshida N
- Organizer
  The 80th Annual Meeting of Japanese Orthodontic Society & The 5th International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K10141
[Presentation] 3テスラ超高b値拡散強調MRIを用いた細胞内拡散係数の推定2021
- Author(s)
  佐々木美穂、佛坂由可
- Organizer
  第75回NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11674
[Presentation] Effects of Lithium chloride on alveolar bone morphometry, tooth movement and root resorption in rats.2021
- Author(s)
  Kondo A, Hotokezaka H, Hotokezaka Y, Kondo T, Arizono K, Hashimoto M, Yoshida N.
- Organizer
  The 80th Annual Meeting of Japanese Orthodontic Society & The 5th International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K10141
[Presentation] ３テスラ超高b値拡散強調MRIを用いた細胞内拡散係数の推定2021
- Author(s)
  佐々木美穂, 佛坂由可
- Organizer
  第75回 NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-20K10144
[Presentation] 高磁場・超高b値拡散強調MRIを用いた細胞内拡散系数の推定2019
- Author(s)
  佐々木　美穗、佛坂　由可、片山　郁夫、榮田　智、高木　幸則、角　美佐、中村　卓
- Organizer
  日本歯科放射線学会第６０回学術大会
- Data Source
  KAKENHI-PROJECT-17K11674
[Presentation] 高磁場・超高ｂ値拡散強調MRIを用いた細胞内拡散係数の推定2019
- Author(s)
  佐々木　美穗、佛坂　由可、片山　郁夫、榮田　智、高木　幸則、角　美佐、中村　卓
- Organizer
  日本歯科放射線学会　第60回学術大会・第16回定例総会
- Data Source
  KAKENHI-PROJECT-17K11674
[Presentation] DNA損傷と低酸素ストレスに共通するdeath signal経路の同定2018
- Author(s)
  佛坂由可, 片山郁夫, 中村　卓
- Organizer
  日本歯科放射線学会　第59回学術大会・第15回定例総会
- Data Source
  KAKENHI-PROJECT-16K11511
[Presentation] 矯正力負荷時における歯根周囲骨代謝への塩化リチウムの影響―ラットを用いた実験―2018
- Author(s)
  佛坂斉祉, 有薗ケイラ, 佛坂由可, 小原悠
- Organizer
  第36回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16K11511
[Presentation] Lithium chloride affects tooth root movement and reduces root resorption by orthodontics force in rats2018
- Author(s)
  Airi I Kondo, Hitoshi Hotokezaka, Takanobu Kondo, Yuka Hotokezaka, Noriaki Yoshida
- Organizer
  94rd Congress of the European Orthodontic Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11511
[Presentation] DNA損傷と低酸素ストレスに共通するdeath signal経路の同定2018
- Author(s)
  佛坂由可, 片山郁夫, 中村　卓
- Organizer
  日本歯科放射線学会　第59回学術大会・第15回定例総会
- Data Source
  KAKENHI-PROJECT-16K11512
[Presentation] 高磁場・超高ｂ値における拡散強調撮像法2017
- Author(s)
  佐々木　美穗、佛坂　由可、片山　郁夫、榮田　智、角　美佐、中村　卓
- Organizer
  日本歯科放射線学会第58回学術大会
- Data Source
  KAKENHI-PROJECT-17K11674
[Presentation] DNA傷害と低酸素ストレスに共通するdeath Signal経路の同定2016
- Author(s)
  佛坂由可,　片山郁夫, 中村　卓
- Organizer
  日本歯科放射線学会　第57回学術大会・第13回定例総会
- Place of Presentation
  大阪国際会議場「グランキューブ大阪」(大阪府・大阪市)
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26462845
[Presentation] モニタ診断に対応した歯学部臨床実習生への読影教育システムの構築2016
- Author(s)
  佐々木美穗、片山郁夫、佛坂由可、高木幸則、榮田　智、角　美佐、中村　卓
- Organizer
  日本歯科放射線学会　第36回関西・九州合同地方会
- Place of Presentation
  AQUA博多(福岡県・福岡市)
- Data Source
  KAKENHI-PROJECT-26462845
[Presentation] ｃPLA2欠損マウスにおける破骨細胞形成と活性について2016
- Author(s)
  片山郁夫, 佛坂由可, 田代茂樹, 氏家眞幸, 中村　卓
- Organizer
  日本歯科放射線学会　第57回学術大会・第13回定例総会
- Place of Presentation
  大阪国際会議場「グランキューブ大阪」(大阪府・大阪市)
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26462845
[Presentation] ｃPLA2欠損マウスにおける破骨細胞形成と活性について2016
- Author(s)
  片山郁夫, 佛坂由可, 田代茂樹, 氏家眞幸, 中村　卓
- Organizer
  日本歯科放射線学会　第57回学術大会
- Place of Presentation
  大阪国際会議場「グランキューブ大阪」（大阪府・大阪市）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K11512
[Presentation] FEN1欠損によって惹起される細胞老化のp53依存性について2013
- Author(s)
  片山郁夫、佛坂由可、中村　卓
- Organizer
  日本歯科放射線学会第54回総会・学術大会
- Place of Presentation
  福岡県立ももち文化センター（福岡市）
- Data Source
  KAKENHI-PROJECT-25462922
[Presentation] 低酸素状態応答におけるγ-taxilinの役割2012
- Author(s)
  佛坂由可, 片山郁夫, 中村卓
- Organizer
  第53回日本歯科放射線学会総会・学術大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-22592088
[Presentation] 拡散強調を左右する細胞学的要因について2012
- Author(s)
  榮田智,佛坂由可,片山郁夫, 山田敏朗 ,中村卓
- Organizer
  第53回日本歯科放射線学会総会・学術大会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-22592091
[Presentation] 細胞ストレス応答におけるg-taxilinの関与日本歯科放射線学会2011
- Author(s)
  佛坂由可, 片山郁夫, 中村卓
- Organizer
  第31回関西・九州合同地方会
- Place of Presentation
  名古屋
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-21390504
[Presentation] 細胞ストレス応答におけるγ-taxilin の関与2011
- Author(s)
  佛坂由可,片山郁夫,中村卓
- Organizer
  日本歯科放射線学会第31回関西・九州合同地方会
- Place of Presentation
  名古屋
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22592088
[Presentation] In vitro measurement of diffusion coefficient2011
- Author(s)
  榮田智, 佛坂由可, 片山郁夫, 山田敏朗, 中村卓
- Organizer
  第52回日本歯科放射線学会総会・学術大会第18回国際歯顎顔面放射線学会併催
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-22592091
[Presentation] In vitro measurement of diffusion coefficient2011
- Author(s)
  榮田智, 佛坂由可, 片山郁夫, 山田敏朗, 中村卓
- Organizer
  第52回日本歯科放射線学会総会・学術大会第18回国際歯顎顔面放射線学会併催
- Place of Presentation
  広島
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-21390504
[Presentation] 細胞ストレス応答におけるγ-taxilinの関与2011
- Author(s)
  佛坂由可
- Organizer
  日本歯科放射線学会第31回関西・九州合同地方会
- Place of Presentation
  名古屋
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22592088
[Presentation] FEN1活性抑制による細胞老化について2010
- Author(s)
  片山郁夫, 佛坂由可, 中村卓
- Organizer
  第51回日本歯科放射線学会総会・学術大会
- Place of Presentation
  横浜
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21390504
[Presentation] αNAC の低下によってはじまるERストレス由来のアポトーシス2007
- Author(s)
  佛坂由可
- Organizer
  第48回日本歯科放射線学会総会・学術大会
- Place of Presentation
  大宮
- Year and Date
  2007-05-11
- Data Source
  KAKENHI-PROJECT-19592173
[Presentation] αNACの低下によってはじまるERストレス由来のアポトーシス2007
- Author(s)
  佛坂由可、中村卓
- Organizer
  第48回日本歯科放射線学会総会・学術
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-19592173

1. NAKAMURA Takashi (30172406)

# of Collaborated Projects: 29 results

# of Collaborated Products: 37 results
2. KATAYAMA Ikuo (80295089)

# of Collaborated Projects: 26 results

# of Collaborated Products: 31 results
3. TASHIRO Shigeki (20300882)

# of Collaborated Projects: 21 results

# of Collaborated Products: 6 results
4. SUMI Tadateru (80284701)

# of Collaborated Projects: 15 results

# of Collaborated Products: 11 results
5. SASAKI Miho (10437874)

# of Collaborated Projects: 15 results

# of Collaborated Products: 13 results
6. SUMI Misa (90284702)

# of Collaborated Projects: 11 results

# of Collaborated Products: 13 results
7. EIDA Sato (80325662)

# of Collaborated Projects: 9 results

# of Collaborated Products: 13 results
8. ICHIKAWA Youko (90380857)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
9. TAKAGI Yukinori (30295084)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
10. Hotokezaka Hitoshi (90199513)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
11. KIMURA Yasuo (30253686)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. IZUMI Masahiro (40212956)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. TAGAWA Kazuo (00380931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SHIBATA Yoshiyuki (20253685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SATO Hironobu (00145955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YONETSU Kouichi (70167039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. YAMAMOTO Kazuo (70255123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MATSUYAMA Toshifumi (30165922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. Hashimoto Megumi (80724517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 有地淑子 (60232063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 有地榮一郎 (00150459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 山田美穂 (80200749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 宮崎敏博 (10174161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 近藤愛理 (70827633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 近藤崇伸 (20814106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 林田咲 (40644050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 稲富信之 (00868127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. 梅田正博 (60301280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 森石武史 (20380983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 藤田修一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HOTOKEZAKA Yuka 佛坂 由可

光田 由可

Research Projects

Research Products

Co-Researchers

GSK3β阻害による歯根吸収抑制機構の解明－細胞死と破歯細胞活性を標的にして－Principal Investigator

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口腔がんの進展・転移における低酸素環境下でのcPLA2の働きPrincipal Investigator

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the function of cPLA2 in progress and metastasis of tumorPrincipal Investigator

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dual-function stress response proteinPrincipal Investigator

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HOTOKEZAKA Yuka 佛坂由可

光田由可