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HANAWA Hideki  塙 秀樹

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… Alternative Names

塙 秀樹  ハナワ ヒデキ

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Researcher Number 10256977
Affiliation (based on the past Project Information) *help 2007: Nippon Medical School, Medical Department, Assistant
2003 – 2006: 日本医科大学, 医学部, 助手
1996: 日本医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Human genetics / Hematology
Except Principal Investigator
Pediatrics / Biological Sciences
Keywords
Principal Investigator
Leukemia / Insertional mutaeenesis / HIV-1 vector / Retrovirus vector / Sever combined immunodeficiency / Gene theranv / エキソントラップ / インスレーター / SINベクター / MLVベクター … More / HIV1ベクター / 白血病 / 挿入変異 / HIV-1ベクター / レトロウイルスベクター / 重症複合型先天性免疫不全症 / 遺伝子治療 / パルスフィールド法 / c-kit / TEL / t(4;12)(q12;p13)転座 … More
Except Principal Investigator
ウイルスベクター / 遺伝子治療 / Metachromatic leukodystrophy / Mannose-6 phosp[hate receptor / Lysosomal diseases / Blood brain barrier / Viral vector / Gene therapy / トランスサイトーシス / マンノース6リン酸 / アリルスルファターゼ / 異染性白質ジストロフィー / マンノース-6-リン酸受容体 / リソゾーム病 / 血液脳関門 / ATL / エイズ / アデノウイルスベクター / 骨髄幹細胞 / 血管新生抑制因子 / 非分裂細胞 / 白血病 / アンギオスタチン / エンドスタチン / 血管新生阻害 / 膵癌 / 多発性骨髄腫 / リンパ腫 / 血管新生 / 挿入変異 / HIVベクター Less
  • Research Projects

    (4 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (6 People)
  •  Development of assay system to quantify insertional mutagendsis for development of safe retrovirus vectorPrincipal Investigator

    • Principal Investigator
      HANAWA Hideki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human genetics
    • Research Institution
      Nippon Medical School
  •  Non-invasive gene therapy for inherited neurodegenerative disorders (How to cross the BBB?)

    • Principal Investigator
      SHIMADA Takashi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Nippon Medical School
  •  HIVベクターの開発

    • Principal Investigator
      SHIMADA Takashi
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nippon Medical School
  •  t(4;12)転座白血病のTEL/X遺伝子の同定Principal Investigator

    • Principal Investigator
      塙 秀樹
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Hematology
    • Research Institution
      Nippon Medical School

All 2009 2007 2006 Other

All Journal Article Presentation

  • [Journal Article] Leukemogenesis of b2a2-type p210 BCR/ABL in a bone marrow transplantation mouse model using a lentiviral vector2009

    • Author(s)
      Uchida, N., Hanawa, H., Dan, K., Inokuchi, K., Shimada, T.
    • Journal Title

      J Nippon Med Sch. (In press)

    • NAID

      130004146984

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390305
  • [Journal Article] Long-term inhibition of glycosphingolipid accumulation in Fabry model mice by a single systemic injection of AAV1 vector in the neonatal period2009

    • Author(s)
      Ogawa, K., Hirai, Y., Ishizaki, M., Takahashi, H., Hanawa, H., Fukunaga, Y., Shimada, T.
    • Journal Title

      Mol.Genet.Metab. 96

      Pages: 91-96

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390305
  • [Journal Article] Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element2009

    • Author(s)
      Hanawa, H., Yamamoto, M., Zhao, H., Shimada, T., Persons, DA.
    • Journal Title

      Mol.Ther. (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390305
  • [Journal Article] Differential Characteristics of HIV-based vs.SIV-based lentiviral vector systems : gene delivery to neurons and axonal transport of expressed gene2007

    • Author(s)
      Kitagawa, R., Miyachi, S., Hanawa, H., Takada, M., Shimada, T.
    • Journal Title

      Neurosciece Res. 57

      Pages: 550-558

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390305
  • [Journal Article] Systemic Cancer Gene Therapy Using Adeno-associated Virus Type 1 Vector Expressing MDA-7/IL242007

    • Author(s)
      Tahara, I., Miyake, K., Hanawa, H., Kurai, T., Hirai, Y., Ishizaki, M., Uchida, E., Tajiri, T., Shimada, T.
    • Journal Title

      Mol Ther. 15

      Pages: 1805-1811

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390305
  • [Journal Article] Efficient Gene Transfer via Retrograde Transport in Rodent and Primate Brains by an HIV-1-Based Vector Pseudotyped with Rabies Virus Glycoprotein2007

    • Author(s)
      Kato, s., Inoue, K., Kobayashi, K., Yasoshima, Y., Miyachi, S., Inoue, S., Hanawa, H., Shimada, T., Takada, M., Kobayashi, K.
    • Journal Title

      Hum.Gene Ther. 18

      Pages: 1141-1151

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390305
  • [Journal Article] Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element.

    • Author(s)
      Hanawa,H., et al.
    • Journal Title

      Mol.Ther.In press

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390305
  • [Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene therapy2007

    • Author(s)
      Hanawa, H.
    • Organizer
      The 13th Annual Meeting of Japan Society of Gene Therapy
    • Place of Presentation
      名古屋
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590314
  • [Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene the rapy2007

    • Author(s)
      Hanawa, H.
    • Organizer
      American Society of Gene Therapy 10th Annual Meeting
    • Place of Presentation
      Seattle,USA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590314
  • [Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene therapy2007

    • Author(s)
      Hanawa, H
    • Organizer
      American Society of Gene Therapy 10th Annual Meeting
    • Place of Presentation
      Seattle
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590314
  • [Presentation] Development of the insulated HIV-1 vector, which improved in both infectivity and safety2007

    • Author(s)
      Hanawa, H
    • Organizer
      The 52nd Annual Meeting of the Japan Society of Human Genetics
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590314
  • [Presentation] 感染効率と安全性を両立させたインスレーターを導入したHIV-1ベクターの開発2007

    • Author(s)
      塙 秀樹
    • Organizer
      第52回日本人類遺伝学会
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590314
  • [Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene therapy2007

    • Author(s)
      Hanawa, H
    • Organizer
      The 13th Annual Meeting of Japan Society of Gene Therapy
    • Place of Presentation
      Nagoya
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590314
  • [Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene the rapy2007

    • Author(s)
      Hanawa, H.
    • Organizer
      American Society of Gene Therapy 10th Annual Meeting
    • Place of Presentation
      Seattle, USA
    • Data Source
      KAKENHI-PROJECT-18590314
  • [Presentation] The MSCV-U3 Internal Promoter Strongly Activates Surrounding Cellular Promoter in Combination with Self-Inactivating (SIN)-MSCV Vector Backbone2006

    • Author(s)
      Hanawa, H
    • Organizer
      American Society of Gene Therapy 9th Annual Meeting
    • Place of Presentation
      Baltimore
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590314
  • [Presentation] The MSCV-U3 Internal Promoter Strongly Activates Surrounding Cellular Promoter in Combination with Self-Inactivating(SIN)-MSCV Vector Backbone2006

    • Author(s)
      Hanawa, H.
    • Organizer
      American Society of Gene Therapy 9th Annual Meeting
    • Place of Presentation
      Baltimore
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590314
  • 1.  SHIMADA Takashi (20125074)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 2.  MIYAKE Koichi (90267211)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  MIGITA Makoto (50256963)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  WATANABE Atsushi (10307952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MOCHIZUKI Hideki (90230044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  久安 早苗 (00089616)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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