ISHIHARA Katsuhiko 石原克彦

… Alternative Names

Katsuhiko Ishihara 石原克彦

ISHIHARA Katsuhito 石原克彦

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Researcher Number	10263245
Other IDs
External Links
Affiliation (Current)	2025: 川崎医療福祉大学, 医療福祉マネジメント学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2021: 川崎医科大学, 医学部, 教授 2007 – 2011: Kawasaki Medical School, 医学部, 教授 2008: Kawasaki Medical School, 教授 2002 – 2006: 大阪大学, 生命機能研究科, 助教授 2003: 阪大, 助教授 … More 2001: 大阪大学, 医学系研究科, 助教授 1999: Osaka University Graduate School of Medicine, Associate Professor, 医学系研究科, 助教授 1998: 大阪大学, 医学部, 助教授 1996: Osaka University, Medical School, Assistant Professor, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Experimental pathology / Biological Sciences / Immunology / Immunology / 免疫の制御機構 Except Principal Investigator Basic Section 54030:Infectious disease medicine-related / Biological Sciences / Experimental pathology / 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator gp130 / IL-6 / 関節リウマチ / STAT3 / ノックインマウス / CD157 / ノックアウトマウス / CD38 / pX / HTLV-1 … More / Rheumatoid arthritis / BST-1/CD157 / ADPリボシルシクラーゼ / マウスモデル / 疾患モデル動物 / 自己免疫疾患 / 樹状細胞 / クラスII MHC / BST-1 / 滑膜 / 関節リウマチモデル / CD157レポーターマウス / CX3CR1 / 単球・マクロファージ亜集団 / マクロファージ様滑膜細胞 / gp130F759 / 骨髄系細胞特異的BST-1欠損 / Bst1-flox / TLR2 / ROS産生 / 可溶性BST-1 / 血管新生 / IL-6/gp130 / 末梢血単球亜集団 / マクロファージ / 滑膜炎 / preclinical phase / 線維化 / 滑膜細胞 / IL-6/gp130/STAT3 / 活性酸素 / Toll様受容体2 / 単球・マクロファージ / 結核 / dendritic cell / mouse models / トランスジェニックマウス / HTLV-1pX / 自己免疫疾患マウスモデル / knockout mouse / B cell / stromal cell / ストロ-マ細胞 / ectoenzyme / 抗体産生 / 慢性関節リウマチ / B細胞 / ストローマ細胞 / 腸内常在細菌叢 / 無菌化(germ free) / 1型胸腺非依存性抗原 / メタボローム解析 / 腸管内常在細菌叢 / 無菌マウス / 腸内細菌叢 / IL-17 / サイトカイン / 滑膜繊維芽細胞 / 免疫学 / 滑膜線維芽細胞 / 抗腫瘍免疫 / 抗原提示 / IL-12 / 樹状細胞(BMDC) / チロシンリン酸化 / 受容体 / 骨髄球 / リンパ球前駆細胞 … More Except Principal Investigator IL-6 / サイトカイン / cytokine / BST-1 / 炎症 / TLR / B細胞 / 細胞膜外酵素 / 自然免疫 / 抗体産生 / マクロファージ / 辺縁帯B細胞 / second messenger / intracellular signaling / Zinc / homeostatic proliferation of T cells / memory T cells / 自己免疫疾患 / gp130 / T細胞 / 樹状細胞 / 細胞運動 / 免疫 / STAT3 / GP130 / T 細胞の恒常的な増殖 / メモリー T 細胞 / セカンドメッセンジャー / 細胞内信号 / 亜鉛 / T細胞の恒常的な増殖 / メモリーT細胞 / inflammation / gene expression / signal transduction / bone marrow stromal cell / rheumatoid arthritis / 遺伝子発現 / シグナル伝達 / 骨髄ストローマ / 慢性関節リウマチ / 血圧 / TNFα / NAD(P)H oxidase / 酸化ストレス / うっ血性心不全 / 心肥大 / 血管障害 / 活性酸素 / 内皮機能 / アンジオテンシン / 関節炎モデル / アジュバント関節炎 / 関節リウマチ Less

A novel regulatory mechanism for innate immune signals by ectoenzymes BST-1 and CD38
- Principal Investigator
  
  Iseki Masanori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kawasaki Medical School
Roles for CD157 in functions of macrophage lineage cells and early pathophysiology of a rheumatoid arthritis modelPrincipal Investigator
- Principal Investigator
  
  Ishihara Katsuhiko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kawasaki Medical School
Function of extracellular ADP-ribosyl cyclase BST-1/CD157 in the intestinePrincipal Investigator
- Principal Investigator
  
  Katsuhiko Ishihara
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kawasaki Medical School
Spatiotemporal pathophysiology of systemic immunological disorders and autoimmune arthritis caused by aberrant cytokine signalingPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Katsuhiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kawasaki Medical School
Investigation of the mechanism of cardiovascular damage in a rat model of arthritis
- Principal Investigator
  
  MORITA Yoshitaka
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kawasaki Medical School
Abnormality of synovial mesenchymal cells in autoimmune arthritisPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Katsuhiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kawasaki Medical School
HTLV-1感染による関節炎の増悪機構Principal Investigator
- Principal Investigator
  
  石原克彦
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
樹状細胞による自己および抗腫瘍免疫制御機構の解析Principal Investigator
- Principal Investigator
  
  石原克彦
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Regulation of Immune responses and autoimmune diseases by cytokines
- Principal Investigator
  
  HIRANO Toshio
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Mechanisms to facilitate the development of autoimmune arthritis by over-expression of HTLV-1pX.Principal Investigator
- Principal Investigator
  
  ISHIHARA Katsuhiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Gp130からのシグナルによる樹状細胞の抗腫瘍活性及び自己免疫の制御Principal Investigator
- Principal Investigator
  
  石原克彦
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Gp130からのシグナルによる樹状細胞抗原提示機能の制御機構の解析Principal Investigator
- Principal Investigator
  
  石原克彦
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Analysis of the function of bone marrow stromal cell antigen, BST-1 (CD157) to support B cellsPrincipal Investigator
- Principal Investigator
  
  ISHIHARA Katsuhiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Bリンパ球初期分化を制御する情報伝達機構Principal Investigator
- Principal Investigator
  
  石原克彦
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  免疫の制御機構
- Research Institution
  Osaka University
Molecular mechanisms of chronic inflammaroty proliferative disease
- Principal Investigator
  
  HIRANO Toshio
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Osaka University

[Book] Molecular mechanisms of rheumatoid arthritis revealed by categorizing subtypes of fibroblast-like synoviocytes. in Rheumatoid Arthritis-Etiology, and Consequences and Co-morbidities2012
- Author(s)
  Ishihara K & Igarashi H
- Publisher
  InTech
- URL
  http://www.intechopen.com/articles/show/title/molecular-mechanisms-of-rheumatoid-arthritis-revealed-by-categorizing-subtypes-of-fibroblast-like-sy
- Data Source
  KAKENHI-PROJECT-21590448
[Book] Molecular mechanisms of rheumatoid arthritis revealed by categorizing subtypes of fibroblast-like synoviocytes. in Rheumatoid Arthritis-Etiology, and Consequences and Co-morbidities2012
- Author(s)
  Ishihara K, Igarashi H
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-21590448
[Book] 免疫生物学 15章免疫応答の人為的制御2010
- Author(s)
  石原克彦, 平野俊夫
- Total Pages
  900
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21590448
[Book] Reviews of Physiology, Biochemistry and Pharmacology2003
- Author(s)
  Kamimura, D., Ishihara, K., Hirano, T.
- Total Pages
  38
- Publisher
  Springer-Verlag
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Journal Article] Imatinib has minimal effects on inflammatory and osteopenic phenotypes in a murine cherubism model2021
- Author(s)
  Mukai Tomoyuki、Akagi Takahiko、Hiramatsu Asano Sumie、Tosa Ikue、Ono Mitsuaki、Kittaka Mizuho、Ueki Yasuyoshi、Yahagi Ayano、Iseki Masanori、Oohashi Toshitaka、Ishihara Katsuhiko、Morita Yoshitaka
- Journal Title
  
  Oral Diseases
  
  Volume: － Issue: 3 Pages: 0-0
- DOI
  10.1111/odi.14073
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-19H03842, KAKENHI-PROJECT-21K08484, KAKENHI-PROJECT-20K21678
[Journal Article] Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages.2020
- Author(s)
  Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, Kim IJ, Silva E, Vitangcol K, Shin KO, Lee YM, Riley R, Ben-Sahra I, Ott M, Ishihara K, Quake SR, Newman J, Brenner C, Campisi J, Verdin E. et al
- Journal Title
  
  Nat Metab
  
  Volume: 2 Issue: 11 Pages: 1265-1283
- DOI
  10.1038/s42255-020-00305-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Journal Article] Distinct physical condition and social behavior phenotypes of CD157 and CD38 knockout mice during aging.2020
- Author(s)
  2.Maria Gerasimenko; Olga Lopatina; Anna A. Shabalova; Stanislav M. Cherepanov; Alla B. Salmina; Shigeru Yokoyama; Hisanori Goto; Hiroshi Okamoto; Yasuhiko Yamamoto; Katsuhiko Ishihara; Haruhiro Higashida.
- Journal Title
  
  PLoS One
  
  Volume: 15(12) Issue: 8 Pages: 4169-4169
- DOI
  10.3390/ijms22084169
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798, KAKENHI-PROJECT-18K08398, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-21K08484
[Journal Article] Functional analysis of a novel G87V TNFRSF1A mutation in patients with TNF receptor-associated periodic syndrome2019
- Author(s)
  Tsuji, S. Matsuzaki, H. Iseki, M. Nagasu, A. Hirano, H. Ishihara, K. Ueda, N. Honda, Y. Horiuchi, T. Nishikomori, R. Morita, Y. Mukai, T.
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 198 Issue: 3 Pages: 416-429
- DOI
  10.1111/cei.13365
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08299, KAKENHI-PROJECT-19K08923, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-19H03564
[Journal Article] Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice2019
- Author(s)
  Nagasu Akiko、Mukai Tomoyuki、Iseki Masanori、Kawahara Kyoko、Tsuji Shoko、Nagasu Hajime、Ueki Yasuyoshi、Ishihara Katsuhiko、Kashihara Naoki、Morita Yoshitaka
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 5 Pages: 402-402
- DOI
  10.3390/cells8050402
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08398, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-18H02828
[Journal Article] IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis2019
- Author(s)
  Yahagi Ayano、Saika Taro、Hirano Hiroyasu、Takai-Imamura Miwa、Tsuji Fumio、Aono Hiroyuki、Iseki Masanori、Morita Yoshitaka、Igarashi Hideya、Saeki Yukihiko、Ishihara Katsuhiko
- Journal Title
  
  RMD Open
  
  Volume: 5 Issue: 2 Pages: e000853-e000853
- DOI
  10.1136/rmdopen-2018-000853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08798, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-17K16217
[Journal Article] CD157 Confers Host Resistance to Mycobacterium tuberculosis via TLR2-CD157-PKCzeta-Induced Reactive Oxygen Species Production2019
- Author(s)
  Yang Qianting、Liao Mingfeng、Wang Wenfei、Zhang Mingxia、Chen Qi、Guo Jiubiao、Peng Bin、Huang Jian、Liu Haiying、Yahagi Ayano、Xu Xingzhi、Ishihara Katsuhiko、Cooper Andrea、Chen Xinchun、Cai Yi
- Journal Title
  
  mBio
  
  Volume: 10 Issue: 4
- DOI
  10.1128/mbio.01949-19
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-17K16217
[Journal Article] CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties.2018
- Author(s)
  Wakabayashi T, Naito H, Suehiro JI, Lin Y, Kawaji H, Iba T, Kouno T, Ishikawa-Kato S, Furuno M, Takara K, Muramatsu F, Weizhen J, Kidoya H, Ishihara K, Hayashizaki Y, Nishida K, Yoder MC, Takakura N.
- Journal Title
  
  Cell Stem Cell.
  
  Volume: 22 Issue: 3 Pages: 348-397
- DOI
  10.1016/j.stem.2018.01.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798, KAKENHI-PROJECT-16K20317, KAKENHI-PROJECT-16H02470, KAKENHI-PROJECT-25253093, KAKENHI-PROJECT-17H06838, KAKENHI-PROJECT-16H06147
[Journal Article] Communication impairment in ultrasonic vocal repertoire during the suckling period of Cd157 knockout mice: transient improvement by oxytocin,2017
- Author(s)
  Olga Lopatina, Kazumi Furuhara, Katsuhiko Ishihara, Alla B. Salmina, Haruhiro Higashida.
- Journal Title
  
  Front. Neurosci.
  
  Volume: -
- DOI
  10.3389/fnins.2017.00266
- NAID
  120006343974
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Journal Article] An immunohistochemical, enzymatic, and behavioral study of CD157/BST-1 as a neuroregulator.2017
- Author(s)
  Haruhiro Higashida, Mingkun Liang, Toru Yoshihara, Shirin Akther, Azam Fakhrul, Cherepanov Stanislav, Tae-Sik Nam, Uh-Hyun Kim, Satoka Kasai, Tomoko Nishimura, Naila Al Mahmuda, Shigeru Yokoyama, Katsuhiko Ishihara, Maria Gerasimenko, Alla Salmina, Jing Zhong, Takahiro Tsuji, Chiharu Tsuji and Olga Lopatina.
- Journal Title
  
  BMC Neuroscience
  
  Volume: 18 Issue: 1 Pages: 35-35
- DOI
  10.1186/s12868-017-0350-7
- NAID
  120006306237
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460499, KAKENHI-PROJECT-16K07090
[Journal Article] Selegiline Ameliorates Depression-Like Behavior in Mice Lacking the CD157/BST1 Gene, a Risk Factor for Parkinson’s Disease2017
- Author(s)
  Kasai, S., Yoshiara, T., Lopatina, O., Ishihara, K. and Higashida, H.
- Journal Title
  
  Frontiers in Behavioral Neuroscience
  
  Volume: 印刷中
- DOI
  10.3389/fnbeh.2017.00075
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07090, KAKENHI-PROJECT-17K08798
[Journal Article] TNF receptor type 2 transmits caspase-dependent apoptotic signals in fibroblast-like synoviocytes derived from rheumatoid arthritis.2015
- Author(s)
  Hiroyasu HIRANO, Hideya IGARASHI, Yoshitaka MORITA, Katsuhiko ISHIHARA
- Journal Title
  
  Kawasaki Medical Journal
  
  Volume: 41(2) Pages: 29-40
- NAID
  110009986978
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460499
[Journal Article] Lipo-oxytocin-1, A Novel Oxytocin Analog Conjugated with Two Palmitoyl Groups, Has Long-lasting Effects on Anxiety-related Behavior and Social Avoidance in CD157 Knockout Mice.2015
- Author(s)
  A. Mizuno, S. M. Cherepanov, Y. Kikuchi, A. Fakhrul, S. Akther, K. Deguchi, T. Yoshihara, K. Ishihara, S. Shuto , H. Higashida
- Journal Title
  
  Brain Sci
  
  Volume: 5 Issue: 1 Pages: 3-13
- DOI
  10.3390/brainsci5010003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390023, KAKENHI-PROJECT-26460499, KAKENHI-PROJECT-15H02495
[Journal Article] Infection-Immunity Liaison: Pathogen-driven autoimmune-mimicry (PDAIM)2014
- Author(s)
  Saeki Y, Ishihara K
- Journal Title
  
  Autoimmunity Reviews
  
  Volume: 13 Issue: 10 Pages: 1064-9
- DOI
  10.1016/j.autrev.2014.08.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460499
[Journal Article] Anxiety- and depression-like behavior in mice lacking the CD157/BST1 gene, a risk factor for Parkinson's disease.2014
- Author(s)
  Lopatina O, Yoshihara T, Nishimura T, Zhong J, Akther S, Fakhrul AA, Liang M, Higashida C, Sumi K, Furuhara K, Inahata Y, Huang JJ, Koizumi K, Yokoyama S, Tsuji T, Petugina Y, Sumarokov A, Salmina AB, Hashida K, Kitao Y, Hori O, Asano M, Kitamura Y, Kozaka T, Shiba K, Zhong F, Xie MJ, Sato M, Ishihara K, Higashida H.
- Journal Title
  
  Front Behav Neurosci
  
  Volume: 8 Pages: 1-18
- DOI
  10.3389/fnbeh.2014.00133
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J40171, KAKENHI-PROJECT-23500440, KAKENHI-PROJECT-23700509, KAKENHI-PROJECT-24500419, KAKENHI-PROJECT-24591812, KAKENHI-PROJECT-25293043, KAKENHI-PROJECT-25670091, KAKENHI-PROJECT-26430069, KAKENHI-PROJECT-26460499
[Journal Article] A pro-inflammatoty role for A20 and ABIN family proteins in human fibroblast-like synoviocytes in rheumatoid arthritis2011
- Author(s)
  Igarashi H, Ishihara K, et al
- Journal Title
  
  Immunol.Lett.
  
  Volume: 141 Issue: 2 Pages: 246-253
- DOI
  10.1016/j.imlet.2011.10.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590448, KAKENHI-PROJECT-22591685
[Journal Article] A pro-inflammatory role for A20 and ABIN family proteins in human fibroblast-like synoviocytes in rheumatoid arthritis2011
- Author(s)
  Igarashi H, Yahagi A, Saika T, Hashimoto J, Tomita T, Yoshikawa H, Ishihara K.
- Journal Title
  
  Immunol. Lett
  
  Volume: 141 Pages: 246-253
- URL
  http://dx.doi.org/10.1016/j.imlet.2011.10.011
- Data Source
  KAKENHI-PROJECT-21590448
[Journal Article] TP53 mutations coincide with the ectopic expression of activation-induced cytidine deaminase in the fibroblast-like synoviocytes derivedfrom a fraction of patients with rheumatoid arthritis2010
- Author(s)
  Igarashi H, Hashimoto J, Tomita T, Yoshikawa H, Ishihara K.
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 161 Issue: 1 Pages: 71-80
- DOI
  10.1111/j.1365-2249.2010.04163.x
- Data Source
  KAKENHI-PROJECT-21590448
[Journal Article] TP53 mutations coincide with the ectopic expression of activation-induced cytidine deaminase in the fibroblast-like synoviocytes derived from a fraction of patients with rheumatoid arthritis.2010
- Author(s)
  Hideya Igarashi, Katsuhiko Ishihara, et al.
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 161 Pages: 71-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590448
[Journal Article] Point mutation of tyrosine 759 of the IL-6 family cytokine receptor, gp130, augments collagen-induced arthritis in DBA/1J mice2009
- Author(s)
  Tsuji F, Yoshimi M, Katsura O, Takai M, Ishihara K, Aono H.
- Journal Title
  
  BMC Musculoskelet Dissord
  
  Volume: 10(23)
- URL
  http://www.biomedcentral.com/1471-2474/10/23
- Data Source
  KAKENHI-PROJECT-21590448
[Journal Article] Point mutation of tyrosine 759 of the IL-6 family cytokine receptor, gp130, augments collagen-induced arthritis in DBA/1J mice2009
- Author(s)
  Tsuji F, Yoshimi M, Katsura O, Takai M, Ishihara k, Aono H.
- Journal Title
  
  BMC Musculo -skelet Dissord 10
  
  Pages: 23-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590390
[Journal Article] Point mutation of tyrosine 759 of the IL-6 femily eytokine receptor. gp130, augments collagen-induced arthritis in DBA/1J mice.2009
- Author(s)
  Fumio Tsuji, Katsuhiko Ishihara, Hiroyuki Aono, et al.
- Journal Title
  
  BMC Musculoskeltal disorders 10
  
  Pages: 23-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590390
[Journal Article] Interleukin-6 directly inhibits osteoclast differentiation by suppressing receptor activator of NF-κB signaling pathways.2008
- Author(s)
  Fumio Yoshitake, Shousaku Itoh, Katsuhiko Ishihara, et al.
- Journal Title
  
  Journal of biological chemistry 283
  
  Pages: 11535-11540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590390
[Journal Article] サイトカインとは2008
- Author(s)
  石原克彦
- Journal Title
  
  小児科診療 71
  
  Pages: 2093-2102
- Data Source
  KAKENHI-PROJECT-19590390
[Journal Article] IL-6-gp130-STAT3 in Tcells directs the development of IL-17+T helper cells with a minimum effect on that of Treg in the steady state.2007
- Author(s)
  Nishihara, M., et. al.
- Journal Title
  
  Int. Immunol. 19
  
  Pages: 695-702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002008
[Journal Article] IL-6-gpl30-STAT3 in T cells directs the development of IL-17+Thelper cells with a minimum effect on that of Treg in the steady state.2007
- Author(s)
  Nishihara, M., et al.
- Journal Title
  
  Int. Immunol. 19
  
  Pages: 695-702
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002008
[Journal Article] Homeostatic proliferating CD4 T cells are involved in the pathogenesis of an Omenn syndrome murine model.2007
- Author(s)
  Khiong, K., M.Murakami, K.Ishihara, T.Hirano, et al.
- Journal Title
  
  J. Clin. Invest (in press)
- Data Source
  KAKENHI-PROJECT-15002008
[Journal Article] IL-6-gp130-STAT3 in T cells directs the development of IL-17+T helper cells with a minimum effect on that of Treg in the steady state.2007
- Author(s)
  Nishihara, M.
- Journal Title
  
  Int. Immunol. 19
  
  Pages: 695-702
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Journal Article] TRIF-GEFH1-RhoB cascade regulates surface expression of MHC class II in dendritic cells that is critical for CD4+ T cell activation.2006
- Author(s)
  Kamon, H., T.K.Ishihara, M., Murakami, T.Hirano, et al.
- Journal Title
  
  EMBO J. 25
  
  Pages: 4108-4119
- Data Source
  KAKENHI-PROJECT-15002008
[Journal Article] Autoimmune arthritis associated with mutated IL-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T.2006
- Author(s)
  Sawa, S., Ishihara, M.Murakami, T.Hirano, et al.
- Journal Title
  
  J. Exp. Med. 203
  
  Pages: 1459-1470
- Data Source
  KAKENHI-PROJECT-15002008
[Journal Article] The point mutation of Y759 of the IL-6 family receptor gpl30synergizes with HTLV-1 pX in promoting RA-like arthritis.2004
- Author(s)
  Ishihara, K., et al.
- Journal Title
  
  Int. Immunol. 16
  
  Pages: 455-465
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002008
[Journal Article] The point mutation of Y759 of the IL-6 family receptor gp130 synergizes with HTLV-1 pX in promoting RA-like arth2004
- Author(s)
  Ishihara, K., T.Hirano, et al.
- Journal Title
  
  Int.Immunol. 16
  
  Pages: 455-465
- Data Source
  KAKENHI-PROJECT-15002008
[Journal Article] The point mutation of Y759 of the IL-6 family receptor gp130 synergizes with HTLV-1 pX in promoting RA-like arthritis.2004
- Author(s)
  Ishihara K, et al.
- Journal Title
  
  Int.Immunol. 16
  
  Pages: 455-465
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590439
[Journal Article] The point mutation of Y759 of the IL-6 family receptor gp130 synergizes with HTLV-1 pX in promoting RA-like arthritis.2004
- Author(s)
  Ishihara, K.
- Journal Title
  
  Int. Immunol. 16
  
  Pages: 455-465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Journal Article] The point mutation of Y759 of the IL-6 family receptor gp130 synergizes with HTLV-1 pX in promoting RA-like arthritis.2004
- Author(s)
  Ishihara, K., et al.
- Journal Title
  
  Int.Immunol 16・3
  
  Pages: 455-465
- Data Source
  KAKENHI-PROJECT-15590439
[Journal Article] IL-6 signal transduction and its physiological roles : The signal orchestration model.2003
- Author(s)
  Kamimura, D., K. Ishihara, T. Hirano.
- Journal Title
  
  Reviews of Physiology, Biochemistry and Pharmacology 149
  
  Pages: 1-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Presentation] The investigation of the pathogenesis of TNF Receptor-Associated Periodic Syndrome (TRAPS) using murine TRAPS models2021
- Author(s)
  赤木貴彦, 向井知之, 浅野澄恵, 井関將典, 矢作綾野, 平野紘康, 中野和久, 石原克彦, 守田吉孝
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology（JSI2021）
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] 関節リウマチモデルgp130F759の最初期滑膜細胞におけるシングルセルRNA-seq解析2021
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第65回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] Lack of bone marrow stromal cell antigen-1 (BST-1)/CD157 ameliorated colitis induced by dextran sodium sulfate (DSS)2021
- Author(s)
  Katsuhiko Ishihara , Ayano Yahagi , Masanori Iseki , Ryo Katsumata , Akiko Shiotani
- Organizer
  Virtual Immunology 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] 関節リウマチモデルgp130F759の最初期滑膜細胞のシングルセルRNA-seq解析2021
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第65回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] Lack of bone marrow stromal cell antigen-1 (BST-1)/CD157 ameliorated colitis induced by dextran sodium sulfate (DSS)2021
- Author(s)
  Katsuhiko Ishihara, Ayano Yahagi, Ryo Katsumata, Akiko Shiotani, Masanori Iseki
- Organizer
  VIRTUAL IMMUNOLOGY2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] 関節リウマチモデルgp130F759の最初期病変におけるIL-6-PAD4連関2020
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] BST-1/CD157の欠損による滑膜線維芽細胞のIL-6産生低下により、GP130F759の関節炎における線維化が軽減した。2020
- Author(s)
  石原克彦, 矢作綾野, 井関將典
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] BST-1/CD157はDSS誘発性大腸炎における腸上皮の傷害を促進させる2020
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] BST-1/CD157の欠損による滑膜線維芽細胞のIL-6産生低下により、GP130F759の関節炎における線維化が軽減した。2020
- Author(s)
  石原克彦, 矢作綾野, 井関將典
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] BST-1/CD157はDSS誘発性大腸炎における腸上皮の傷害を促進させる2020
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] 関節リウマチモデルgp130F759の最初期病変におけるIL-6-PAD4連関 -滑膜線維芽細胞と好中球の相互作用-2020
- Author(s)
  矢作綾野、井関將典、石原克彦
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] CX3CR1-eGFP+macrophage-like synoviocytes in gp130F759, a mouse model for rheumatoid arthritis2019
- Author(s)
  Ayano Yahagi, Yujiro Yokoyama, Noritaka Tsunematsu, Masanori Iseki, Katsuhiko Ishihara.
- Organizer
  The 26th International Symposium on Molecular Cell Biology of Macrophages
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] Toll-like receptor-induced Ab production from marginal zone B cells is negatively regulated by ADP-ribosyl cyclase BST-1/CD1572019
- Author(s)
  Masanori Iseki, Ayano Yahagi, Katsuhiko Ishihara
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19K08943
[Presentation] Toll-like receptor-induced Ab production from marginal zone B cells is negatively regulated by ADP-ribosyl cyclase BST-1/CD1572019
- Author(s)
  Masanori Iseki, Ayano Yahagi, Katsuhiko Ishihara
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] IL-6-PAD4 axis: IL-6 dependent PAD4 production in neutrophils at the earliest phase of arthritis in gp130F759.2019
- Author(s)
  Ayano Yahagi, Taro Saika, Masanori Iseki, Katsuhiko Ishihara
- Organizer
  The 48th Annual Meeting of the Japanese for Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] BST-1/CD157 negatively regulates marginal zone B cell survival and Ab production induced with Toll-like receptor stimulation2018
- Author(s)
  Masanori Iseki, Ayano Yahagi, Katsuhiko Ishihara
- Organizer
  The 47th Annual Meeting of the Japanese Society for Immunology, Fukuoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] Elongation of the small intestine and enlargement of the mesenteric lymph nodes in Bst1Cd38 double knockout mice.2018
- Author(s)
  Katsuhiko Ishihara, Ayano Yahagi, Masanori Iseki
- Organizer
  The 47th Annual Meeting of the Japanese Society for Immunology, Fukuoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] Deletion of padi4 exacerbated the arthritis in gp130F759.2018
- Author(s)
  Ayano Yahagi, Masanori Iseki, Kazuhiko Yamamoto, Katsuhiko Ishihara
- Organizer
  The 47th Annual Meeting of the Japanese Society for Immunology, Fukuoka
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] A novel function of ADP-ribosyl cyclases to regulate the length of the small intestine revealed in CD38/CD157 double knockout mice.2018
- Author(s)
  Katsuhiko Ishihara, Ayano Yahagi, Masanori Iseki
- Organizer
  IMMUNOLOGY 2018, 2018.5.4-8, Austin,Texas
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] 関節リウマチモデルgp130F759の初期病態において関節のPadi4遺伝子が増強する2017
- Author(s)
  矢作綾野, 石原克彦
- Organizer
  第28回日本生体防御学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] Bone Marrow Stromal Cell Antigen-1 Identified by RNA-Seq and ChIP-Seq Is important for Inducing Renal Ischemia-Reperfusion Injury and Fibrosis2017
- Author(s)
  Inoue Tsuyoshi, Huang Liping, Rosin Diane L.,Ishihara Katsuhiko, Wada Youichiro, Okusa Mark D.
- Organizer
  Kidney week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] BST-1/CD157 on B cells negatively regulates Toll-like receptor signaling2017
- Author(s)
  Masanori Iseki, Ayano Yahagi, Katsuhiko Ishihara
- Organizer
  第46回日本免疫学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08798
[Presentation] Systemic infection with Mycoplasma fermentans facilitates development of arthritis in the knock-in mice gp130F759 through the action of neutrophils.2016
- Author(s)
  Ayano YAHAGI, Hiroyasu HIRANO, Katsuhiko ISHIHARA
- Organizer
  8th International forum on rheumatoid arthritis 2016
- Place of Presentation
  品川プリンスホテル(東京)
- Year and Date
  2016-10-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460499
[Presentation] Eosinophils are not essential for pathological reactions in experimental allergic rhinitis, but suppress IgE production.2016
- Author(s)
  Taro Saika, Ayano Yahagi, Katsuhiko Ishihara, Yukiyoshi Hyo, Tamotsu Harada
- Organizer
  日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター(宜野湾市)
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460499
[Presentation] Lack of microbiota revealed the role for BST-1/CD157 to maintain the homeostasis at mucosa-MLN interface2016
- Author(s)
  Katsuhiko ISHIHARA, Ayano YAHAGI, Takaaki NISHIMOTO, Masanori ISEKI
- Organizer
  日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター(宜野湾市)
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460499
[Presentation] Mycoplasma fermentans感染により早期化するgp130F759の関節炎発症は好中球依存性である2016
- Author(s)
  矢作　綾野、石原　克彦
- Organizer
  第27回日本生体防御学会
- Place of Presentation
  九州大学病院キャンパスコラボステーションI(福岡市)
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-26460499
[Presentation] Padi4 expression by neutrophils in the synovium appears in the earliest phase of arthritis in gp130F7592016
- Author(s)
  Ayano YAHAGI, Taro SAIKA, Katsuhiko ISHIHARA
- Organizer
  日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター(宜野湾市)
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460499
[Presentation] Enhanced TI-1 antigen responses in BST-1/CD157 knock-out mice of C57BL/6J background.2015
- Author(s)
  Katsuhiko Ishihara, Ayano Yahagi, Takaaki Nishimoto.
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌市)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26460499
[Presentation] Critical roles of neutrophils for development of arthritis in the knock-in mouse gp130F759 induced by systemic infection of Mycoplasma fermentans2015
- Author(s)
  Ayano YAHAGI, Hiroyasu HIRANO, Hideya IGARASHI, Katsuhiko ISHIHARA
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター(北海道・札幌市)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26460499
[Presentation] 線維芽細胞様滑膜細胞株亜型に発現するRA関連遺伝子の探索2011
- Author(s)
  五十嵐英哉、石原克彦, ら
- Organizer
  日本リウマチ学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] RA滑膜線維芽細胞株においてABIN1は炎症促進性に機能する2011
- Author(s)
  五十嵐英哉、石原克彦
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  ポートピアホテル(神戸)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] gp130F759マウスの関節における網羅的発現遺伝子解析2011
- Author(s)
  石原克彦、五十嵐英哉, ら
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  ポートピアホテル(神戸)
- Year and Date
  2011-07-20
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] The pro-inflammatory function of A20 and ABINs in a subtype of fibro blast-like synoviocytes derived from rheumatoid arthritis2011
- Author(s)
  Igarashi H, Ishihara K, et al
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] gp130F759マウスの関節における網羅的発現遺伝子解析2011
- Author(s)
  石原克彦
- Organizer
  第55回日本リウマチ学会総会・学術集会
- Place of Presentation
  神戸ポートピアホテル(神戸)
- Year and Date
  2011-07-20
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] Heterogeneity of gene expression profiles in fibroblast-like synoviocytes of rheumatoid arthritis and osteoarthritis2010
- Author(s)
  Katsuhiko Ishihara
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸ポートピアホテル(神戸)
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] gp130F759マウスの自己免疫性関節炎自然発症経過におけるIL-17の産生2010
- Author(s)
  石原克彦
- Organizer
  第54回日本リウマチ学会
- Place of Presentation
  神戸ポートピアホテル(神戸)
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] Heterogeneity of gene expression profiles in fibroblast-like synoviocytes of rheumatoid arthritis and osteoarthritis2010
- Author(s)
  Katsuhiko Ishihara, Hideya Igarashi
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] Comparative analysis of gene expression in a subtype of fibrobtast-like synoviocytes between rheumatoid arthritis and osteoarthritis2010
- Author(s)
  Hideya Igarashi, Katsuhiko Ishihara
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] gp130F759マウスの自己免疫性関節炎自然発症経過におけるIL-17の産生2010
- Author(s)
  石原克彦、五十嵐英哉, ら
- Organizer
  日本リウマチ学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] 関節リウマチ及び変形性関節症に由来する滑膜線維芽細胞株の亜型別発現遺伝子解析2009
- Author(s)
  石原克彦
- Organizer
  日本免疫学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] 関節リウマチ及び変形性関節症に由来する滑膜線維芽細胞株の亜型別発現遺伝子解析2009
- Author(s)
  Ishihara K
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] 滑膜線維芽細胞様細胞の亜型およびRA特異的な発現遣伝子の網羅的解析2009
- Author(s)
  石原克彦
- Organizer
  リウマチ学会
- Place of Presentation
  国際館パミール(東京都)
- Year and Date
  2009-04-25
- Data Source
  KAKENHI-PROJECT-21590448
[Presentation] Search for cell-intrinsic abnormalities of synovial fibroblasts in rheumatoid arthritis2007
- Author(s)
  Katsuhiko Ishihara, Hideya Igarashi, Toshiyuki Fukada, Masaaki Murakami and Toshio Hirano
- Organizer
  第37回日本免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590390
[Presentation] Involvement of STAT3 signaling for IL-6-mediated development of IL-17 producing CD4 T cells.2006
- Author(s)
  Nishihara, M.
- Organizer
  The 36^<th> Annual Meting of the Japanese Society for Immunology
- Place of Presentation
  Osaka International Convention Center, Osaka, Japan.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Presentation] Aberrant signal of gpl30 and autoimmune arthritis2004
- Author(s)
  石原克彦
- Organizer
  シンポジウム「The Forefront of B Cell Research」
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2004-10-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Presentation] サイトカインシグナル異常による関節リウマチマウスモデル2004
- Author(s)
  石原克彦
- Organizer
  第6回なにわ骨代謝・骨腫瘍研究会特別講演
- Place of Presentation
  ホテルニューオータニ大阪
- Year and Date
  2004-10-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Presentation] A mouse model of rheumatoid arthritis developed by aberrant cytokine signaling.2004
- Author(s)
  Ishihara, K.
- Organizer
  The 6^<th> Naniwa Society for Bone metabolism and tumor. Special lecture
- Place of Presentation
  Hotel New Otani Osaka, Japan.
- Year and Date
  2004-10-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Presentation] Aberrant signal of gp130 and autoimmune arthritis2004
- Author(s)
  Ishihara, K.
- Organizer
  Symposium 「The Forefront of B Cell Research」
- Place of Presentation
  The Institute of Medical Science, The University of Tokyo, Japan.
- Year and Date
  2004-10-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Presentation] サイトカイン受容体gpl30の点変異に由来する自己免疫性関節炎マウスの滑膜組織における免疫担当細胞の局在2003
- Author(s)
  石原克彦
- Organizer
  第33回日本免疫学会総会・学術集会
- Place of Presentation
  福岡国際会議場マリンメッセ福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Presentation] Localization of immune cells in the synovial tissues of autoimmune rheumatoid arthritis-gp130^<F759/F759> mice.2003
- Author(s)
  Ishihara, K.
- Organizer
  The 33^<th> Annual Meting of the Japanese Society for Immunology
- Place of Presentation
  Fukuoka International Convention Center, Fukuoka, Japan.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Presentation] A mouse model of rheumatoid arthritis developed by aberrant signal of cytokine receptor gp130.2003
- Author(s)
  Ishihara, K.
- Organizer
  The 9^<th> Autoimmunity Workshop
- Place of Presentation
  Tokai University Alumni Hall, Japan.
- Year and Date
  2003-07-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002008
[Presentation] サイトカイン受容体gpl30のシグナル異常により発症する関節リウマチマウスモデル2003
- Author(s)
  石原克彦
- Organizer
  第9回自己免疫研究会
- Place of Presentation
  東海大学校学友館
- Year and Date
  2003-07-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15002008

1. IGARASHI Hideya (40291538)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
2. 矢作綾野 (10584873)

# of Collaborated Projects: 3 results

# of Collaborated Products: 31 results
3. HIRANO Toshio (40136718)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. Iseki Masanori (30532353)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
5. MORITA Yoshitaka (50346441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. SATOH Minoru (70449891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YADA Toyotaka (00210279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MURAKAMI Masaaki (00250514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. YAMASHITA Susumu (90346148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HIRANO Hiroyasu

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 西小森隆太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 向井知之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 長洲一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 周東智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 東田陽博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIHARA Katsuhiko 石原 克彦

Katsuhiko Ishihara 石原 克彦

ISHIHARA Katsuhito 石原 克彦

Research Projects

Research Products

Co-Researchers

A novel regulatory mechanism for innate immune signals by ectoenzymes BST-1 and CD38

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Roles for CD157 in functions of macrophage lineage cells and early pathophysiology of a rheumatoid arthritis modelPrincipal Investigator

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Function of extracellular ADP-ribosyl cyclase BST-1/CD157 in the intestinePrincipal Investigator

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Spatiotemporal pathophysiology of systemic immunological disorders and autoimmune arthritis caused by aberrant cytokine signalingPrincipal Investigator

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Investigation of the mechanism of cardiovascular damage in a rat model of arthritis

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Abnormality of synovial mesenchymal cells in autoimmune arthritisPrincipal Investigator

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HTLV-1感染による関節炎の増悪機構Principal Investigator

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樹状細胞による自己および抗腫瘍免疫制御機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Regulation of Immune responses and autoimmune diseases by cytokines

Principal Investigator

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Research Institution

Mechanisms to facilitate the development of autoimmune arthritis by over-expression of HTLV-1pX.Principal Investigator

Principal Investigator

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Gp130からのシグナルによる樹状細胞の抗腫瘍活性及び自己免疫の制御Principal Investigator

Principal Investigator

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Review Section

Research Institution

Gp130からのシグナルによる樹状細胞抗原提示機能の制御機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the function of bone marrow stromal cell antigen, BST-1 (CD157) to support B cellsPrincipal Investigator

Principal Investigator

ISHIHARA Katsuhiko 石原克彦

Katsuhiko Ishihara 石原克彦

ISHIHARA Katsuhito 石原克彦

[Book] 免疫生物学 15章免疫応答の人為的制御2010