Takenaka Shigeo 竹中重雄

… Alternative Names

TAKENAKA Shigeo 竹中重雄

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Researcher Number	10280067
Other IDs
External Links
Affiliation (Current)	2025: 大阪公立大学, 大学院生活科学研究科 , 教授
Affiliation (based on the past Project Information) *help	2025: 大阪公立大学, 大学院生活科学研究科, 教授 2022 – 2023: 大阪公立大学, 大学院生活科学研究科, 教授 2017 – 2021: 大阪府立大学, 総合リハビリテーション学研究科, 教授 2017: 大阪府立大学, 公私立大学の部局等, 教授 2013 – 2016: 大阪府立大学, 生命環境科学研究科, 准教授 … More 2011 – 2016: 大阪府立大学, 生命環境科学研究科(系), 准教授 2007 – 2011: Osaka Prefecture University, Graduate School of Life and Environmental Science, Associate Professor 2010: 大阪府立大学, 大学院・生命環境科学研究科, 准教授 2005 – 2006: Osaka Prefecture University, Graduate School of Life and Environmental Sciences, Associate Professor, 生命環境科学研究科, 助教授 2003 – 2004: Osaka Prefecture University, Graduate School of Agriculture and Biosciences, Associate Professor, 農学生命科学研究科, 助手 2002: 大阪府立大学, 大学院・農学生命科学研究科, 助手 1999 – 2001: 羽衣学園短期大学, 人間生活学科, 助教授 1996 – 1998: 羽衣学園短期大学, 家政学科・食物専攻, 講師 Less
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Integrative animal science / Basic veterinary science/Basic zootechnical science Except Principal Investigator Veterinary medical science / Clinical veterinary science / Basic Section 55050:Anesthesiology-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 42020:Veterinary medical science-related / Basic Section 58070:Lifelong developmental nursing-related / Anesthesiology … More / Applied veterinary science / Applied molecular and cellular biology / Applied molecular and cellular biology / 食生活 / Risk sciences of radiation and chemicals / Anesthesiology/Resuscitation studies / Risk sciences of radiation/Chemicals / Science and Engineering / 家政学 Less
Keywords	Principal Investigator RNAi / ビタミンB12 / 神経細胞分化 / 神経細胞 / 覚醒 / 睡眠 / LCMS / 代謝解析 / 代謝 / 補酵素型 … More / 赤芽球 / CRISPR/CAS9 / 酸化ストレス / 代謝異常 / 神経疾患 / 欠乏 / 認知機能 / GCMS / SH-SY5 / アデノシルB12 / エネルギー代謝 / メチルマロン酸 / レイチノイン酸 / 分化 / 神経 … More Except Principal Investigator マクロファージ / 海馬 / 肝線維化 / 筋線維芽細胞 / FT-MS / 腎線維化 / メタボロミクス / アストロサイト / ミクログリア / TGF-β / Smad / 全脳虚血 / 薬剤性肝障害 / 炎症 / 慢性肝疾患 / 鉄過剰 / P450 / FT-ICR MS / 質量分析 / 虚血耐性 / 脳虚血 / 脳神経疾患 / ラット / 線維化 / EMT / ノックダウン / 脱塩基部位 / グリコシラーゼ / 塩基除去修復 / 細胞骨格 / 抗原提示マクロファージ / 創傷治癒線維化 / Thy-1 / アンセリン / ビタミンB_<12> / スサビノリ / オレイン酸 / cis-バクセン酸 / 一価不飽和脂肪酸 / グリア細胞 / TGF-beta / 細胞保護作用 / 細胞保護機構 / 薬物性肝障害 / 脂肪肝 / 細胞死 / 脂肪性肝疾患 / 肝毒性 / 肝鉄過剰 / 就労女性 / 微量栄養素 / 健康診断 / 栄養調査 / プレコンセプション / 助産師 / 栄養分析 / 葉酸 / ビタミンB12 / ビタミンB6 / 食事歴 / 食生活 / リテラシー / 栄養素摂取 / 教育プログラム / プレコンセプションケア / 脳内炎症反応 / 酸化ストレス / 肝障害 / 肝硬変 / 薬剤性肝傷害 / 代謝性肝疾患 / アルドラーゼ / アコニターゼ / 海馬神経細胞 / 再生獣医療 / 獣医再生医療 / センダイウイルスベクター / 血液 / ネコ / イヌ / 獣医学 / 再生医療 / 多能性幹細胞 / iPS細胞 / neural stem cell / regeneration / myelin / demvelination / 神経幹細胞 / 再生 / ミエリン / 脱髄 / Fourier Transform Ion Cyclotron Mass Spectrometry / Metabolomics / 多変量解析 / フーリエ変換質量分離装置 / Arabidopsis / plat / mass spectrometry / metabolomics / cytochrome P450 / シロイヌナズナ / ミトコンドリア / フェレドキシン還元酵素 / フェレドキシン / ミトクロムP450 / ゲノム / 植物 / シトクロムP450 / usujilene / anserine / methylmakonic acid / vitamin B_<12>-deficientrat / Porphyra yezoensis / antioxidant / vitamin B_<12> analogue / chemiluminescence / 過酸化ペルオキシド / 補酵素型B_<12> / ウスジレン / メチルマロン酸 / B_<12>欠乏ラット / 抗酸化物質 / ビタミンB_<12>アナログ / ケミルミネッセンス / 難治性疾患 / 上皮‐間葉転換 / 臓器横断的解析 / 臓器横断的 / 皮膚線維化 / 病理学 / DNA修復制御 / 修復複合体 / ノックダウン細胞 / ＨｅＬａ細胞 / マウス胎児線維芽細胞 / ＤＮＡ修復 / DNA損傷 / AP site / ATM / ｐ53 / タンパク質間相互作用 / APEX / Pol beta / タンパク質相互作用 / RPA2 / PIKK / MPG / DSB / プロテオーム解析 / プロテオーム / 膵線維化 / 遡及現象 / 線維化腎 / α-平滑筋アクチン / betaーカテニン / 萎縮腎 / 獣医病理学 / PGE2 / 平滑筋アクチン / 幹細胞 / 毛根鞘細胞 / 体性幹細胞 / 毛嚢上皮 / 胆管上皮 / 尿細管上皮 / 上皮－間葉転換 / Galactin-3 / HSP25 / 抗原提示能 / カルポニン / Hsp25 / 皮膚創傷治癒 / 胆管周囲線維化 / 皮膚創傷治癒線維化 / 慢性腎臓病 / プロスタグランデン / 尿細管再生 / MHCクラスII / 誘導因子 / snRNA / 蛍光ARP / shRNA / 化学物質 / 放射線 / 修復酵素 / ノックアウトMEF / ARP / FARP-1 / DAN polymeraseβ / RNAi / 細胞周期 / FARP法 / ARP法 / AP部位 / 細胞モデル / MCP-1 / EP4 / シクロオキシゲー / 血管新生 / 骨髄幹細胞 / 腎線維化モデル / 応用動物学 / 病理発生 / 病態 / 同定 / 微量定量 / 内生メタボライト / MSMSフラグメント / MS / FT-ICR / 抗菌性 / ケミカルルミネッセンス / コバルト / メチルマロン酸尿症 / ビタミンB_<12>欠乏ラット / 抗酸化性 / カルノシン / ビタミンC Less

天然の健康成分：n-5系・n-6系・n-7系一価不飽和脂肪酸の細胞内動態解析
- Principal Investigator
  
  岩城俊雄
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Osaka Metropolitan University
全脳虚血後海馬グリア細胞におけるTGF-β1/Smadシグナルの機能的意義の解明
- Principal Investigator
  
  中島崇行
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Function of Vitamin B12 in BrainPrincipal Investigator
- Principal Investigator
  
  Takenaka Shigeo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Elucidation of novel mechanism for hepatoprotection by iron overload
- Principal Investigator
  
  Izawa Takeshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Development of a nutritional status improvement program for working women based on preconception care
- Principal Investigator
  
  Watanabe Kaori
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58070:Lifelong developmental nursing-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
The relationship between Smad signaling and ischemia-induced brain inflammation
- Principal Investigator
  
  Nakajima Takayuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Osaka Prefecture University
Elucidation of the mechanism for disease modulation by iron overload in chronic liver diseases
- Principal Investigator
  
  Izawa Takeshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Osaka Prefecture University
Investigation of erythroid differentiation using transgene-free canine and feline induced pluripotent stem cells
- Principal Investigator
  
  Hatoya Shingo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Osaka Prefecture University
Vitamin B12 metabolism and its relation for neural and cognitive functionsPrincipal Investigator
- Principal Investigator
  
  Takenaka Shigeo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  Osaka Prefecture University
In vitro study of the functinal significane of ischemic tolerance-induced changes in the expression level of aconitase2 and aldolase A
- Principal Investigator
  
  Nakajima Takayuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Osaka Prefecture University
Based on the axis between macrophages and myofibroblasts, the organ-cross pathogenesis of incurable fibrosis
- Principal Investigator
  
  Yamate Jyoji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Osaka Prefecture University
Regulation of the initiation of base excision repair by the protein-protein interactions
- Principal Investigator
  
  KUBO KIHEI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Osaka Prefecture University
Function of vitamin B12 on neural cell differentiation and an insight on cognitive symptom.Principal Investigator
- Principal Investigator
  
  TAKENAKA Shigeo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Osaka Prefecture University
Molecular mechanisms of ischemic tolerance in the brain
- Principal Investigator
  
  TAKAYUKI Nakajima
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Osaka Prefecture University
Pathogenesis of epithelial-mesenchymal transition relating to progressing fibrosis and its clinical significance
- Principal Investigator
  
  YAMATE Jyoji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Clinical veterinary science
- Research Institution
  Osaka Prefecture University
The pathogenesis of progressive chronic renal disease and therapeutic strategies, based on the axis of macrophages and myofibroblasts
- Principal Investigator
  
  YAMATE Jyoji
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Osaka Prefecture University
Analysis of cell cycle-dependent base excision repair by a novel direct method for detecting the intracellular AP sites
- Principal Investigator
  
  KUBO Kihei
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Osaka Prefecture University
フーリエ変換質量分析による超微量生体分子の検出と同定・定量システムの基盤創造
- Principal Investigator
  
  OHTA Daisaku
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka Prefecture University
Based on the relationship of macrophages-myofibroblasts, the pathogenesis of renal fibrosis and its therapeutic strategies
- Principal Investigator
  
  YAMATE Jyoji
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Osaka Prefecture University
Studies on the mechanism of myelin regeneration using mutant rats with myelin disorders
- Principal Investigator
  
  KUWAMURA Mitsuru
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  Osaka Prefecture University
Plant Metabolomics Research on a basis of Fourier Transform Ion Cyclotron Mass Spectrometry
- Principal Investigator
  
  OHTA Daisaku
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Osaka Prefecture University
Plant Metabolomics towards understanding of the molecular diversity and functional specificity of the P450 containing electron trnasfer chain
- Principal Investigator
  
  OHTA Daisaku
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Osaka Prefecture University
Fund-Nutritional Properties of Physiological Functions of Vitamin Biz and Antioxidative Substances of Algae
- Principal Investigator
  
  TAMURA Yoshiyuki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  食生活
- Research Institution
  Hagoromo Gakuen Junior College
藻類のビタミンB_<12>の蓄積機構と食品栄養的機能性への利用について
- Principal Investigator
  
  TAMURA Yoshiyuki
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  家政学
- Research Institution
  Hagoromo Gakuen Junior College

[Journal Article] Oxygen-glucose deprivation-induced glial cell reactivity in the rat primary neuron-glia co-culture2023
- Author(s)
  Inoue M, Tanida T, Kondo T, Takenaka S, Nakajima T.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 85 Issue: 8 Pages: 799-808
- DOI
  10.1292/jvms.23-0175
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08927, KAKENHI-PROJECT-23K07340, KAKENHI-PROJECT-20K08186
[Journal Article] The expression and phosphorylation of SMAD3 protein in microglia and astrocytes of the rat hippocampus after transient global cerebral ischemia2022
- Author(s)
  Nakajima T, Tanaka Y, Takahashi Y, Kondo T, Takenaka S.
- Journal Title
  
  J Chem Neuroanat.
  
  Volume: 125 Pages: 102146-102146
- DOI
  10.1016/j.jchemneu.2022.102146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08927
[Journal Article] Changes in Smad1/5/9 expression and phosphorylation in astrocytes of the rat hippocampus after transient global cerebral ischemia2021
- Author(s)
  Nakajima T, Kunieda Y, Takahashi Y, Tanaka Y, Kondo T, Takenaka S.
- Journal Title
  
  J Chem Neuroanat.
  
  Volume: 113 Pages: 101941-101941
- DOI
  10.1016/j.jchemneu.2021.101941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08862
[Journal Article] Cytochrome P450 2A6 and other human P450 enzymes in the oxidation of flavone and flavanone2018
- Author(s)
  Kakimoto Kensaku、Murayama Norie、Takenaka Shigeo、Nagayoshi Haruna、Lim Young-Ran、Kim Vitchan、Kim Donghak、Yamazaki Hiroshi、Komori Masayuki、Guengerich F. Peter、Shimada Tsutomu
- Journal Title
  
  Xenobiotica
  
  Volume: 48 Issue: 2 Pages: 1-12
- DOI
  10.1080/00498254.2018.1426133
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07770, KAKENHI-PROJECT-16K09119, KAKENHI-PROJECT-17K08426
[Journal Article] Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants2017
- Author(s)
  Shimada Tsutomu、Murayama Norie、Kakimoto Kensaku、Takenaka Shigeo、Lim Young-Ran、Yeom Sora、Kim Donghak、Yamazaki Hiroshi、Guengerich F. Peter、Komori Masayuki
- Journal Title
  
  Xenobiotica
  
  Volume: 49 Issue: 6 Pages: 1-11
- DOI
  10.1080/00498254.2017.1347306
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07770, KAKENHI-PROJECT-16K09119
[Journal Article] Production of feline leukemia inhibitory factor with biological activity in Escherichia coli.2016
- Author(s)
  Kanegi R, Hatoya S, Tsujimoto Y, Takenaka S, Nishimura T, Wijewardana V, Sugiura K, Takahashi M, Kawate N, Tamada H, Inaba T.
- Journal Title
  
  Theriogenology
  
  Volume: 印刷中 Issue: 2 Pages: 604-611
- DOI
  10.1016/j.theriogenology.2016.02.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07747, KAKENHI-PROJECT-15K14888, KAKENHI-PROJECT-24380172, KAKENHI-PROJECT-16H05044, KAKENHI-PROJECT-15K07738
[Journal Article] AP endonuclease knockdown enhances methyl methanesulfonate hypersensitivity of DNA polymerase β knockout mouse embryonic fibroblast2015
- Author(s)
  Yamamoto, R., Umetsu, M., Yamamoto, M., Matsuyama, S., Takenaka, S., Ide, H., Kubo, K.
- Journal Title
  
  Jounal of Radiation Research
  
  Volume: 56 Issue: 3 Pages: 462-466
- DOI
  10.1093/jrr/rru125
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25340036
[Journal Article] Profiling of plasma metabolites in canine oral melanoma using gas chromatography-mass spectrometry2015
- Author(s)
  Kawabe M, Baba Y, Tamai R, Yamamoto R, Komori M, Mori T, Takenaka S.
- Journal Title
  
  Journal of veterinary Medical Science
  
  Volume: 77 Pages: 1025-8
- NAID
  130005094686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25340036
[Journal Article] Oxidation of Acenaphthene and Acenaphthylene by Human Cytochrome P450 Enzymes.2015
- Author(s)
  Shimada T, Takenaka S, Murayama N, Yamazaki H, Kim JH, Kim D, Yoshimoto FK, Guengerich FP, Komori M.
- Journal Title
  
  Chem Res Toxicol.
  
  Volume: 28 Issue: 2 Pages: 268-278
- DOI
  10.1021/tx500505y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24580428
[Journal Article] Profiling of plasma metabolites in canine oral melanoma using gas chromatography-mass spectrometry2015
- Author(s)
  Kawabe, M., Baba, Y., Tamai, R., Yamamoto, R., Komori, M., Takenaka, S.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 77 Issue: 8 Pages: 1025-1028
- DOI
  10.1292/jvms.14-0641
- NAID
  130005094686
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07770
[Journal Article] Proteomic analysis of the hippocampus in naive and ischemic-preconditioned rat2015
- Author(s)
  Nakajima T, Hata R, Kondo T, Takenaka S
- Journal Title
  
  Journal of Neurological Science
  
  Volume: 358 Issue: 1-2 Pages: 158-171
- DOI
  10.1016/j.jns.2015.08.1530
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10520
[Journal Article] Profiling of plasma metabolites in canine oral melanoma using gas chromatography-mass spectrometry.2015
- Author(s)
  Kawabe M, Baba Y, Tamai R, Yamamoto R, Komori M, Mori T, Takenaka S.
- Journal Title
  
  J Vet Med Sci.
  
  Volume: 77
- NAID
  130005094686
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24580428
[Journal Article] Abundance of BER-related proteins depends on the cellular proliferation status and presence of DNA polymerase β2015
- Author(s)
  Yamamoto, M., Yamamoto, R., Takenaka, S., Matsuyama, S., Kubo, K.
- Journal Title
  
  Jounal of Radiation Research
  
  Volume: 56 Issue: 4 Pages: 707-712
- DOI
  10.1093/jrr/rrv010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25340036
[Journal Article] Gas chromatography-mass spectrometry-based metabolic profiling of cerebrospinal fluid from epileptic dogs.2014
- Author(s)
  Hasegawa T, Sumita M, Horitani Y, Tamai R, Tanaka K, Komori M, Takenaka S.
- Journal Title
  
  J Vet Med Sci.
  
  Volume: 76 Pages: 517-522
- NAID
  130003382409
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24580428
[Journal Article] Gas Chromatography-Mass Spectrometry-Based Metabolic Profiling of Cerebrospinal Fluid from Epileptic Dogs2014
- Author(s)
  Hasegawa T, Sumita M, Horitani Y, Tamai R, Tanaka K, Komori M, Takenaka S.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 76 Issue: 4 Pages: 517-522
- DOI
  10.1292/jvms.13-0520
- NAID
  130003382409
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580428, KAKENHI-PROJECT-25513007
[Journal Article] Profiling of serum metabolites in canine lymphoma using gas chromatography mass spectrometry.2014
- Author(s)
  Tamai R, Furuya M, Hatoya S, Akiyoshi H, Yamamoto R, Komori Y, Yokoi S, Tani K, Hirano Y, Komori M, Takenaka S.
- Journal Title
  
  J Vet Med Sci.
  
  Volume: 76 Pages: 1513-1518
- NAID
  130004677727
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24580428
[Journal Article] Distribution of cells labelled by a novel somatic stem cell-recognizing antibody (A3) in pulmonary genesis and bleomycin induced pulmonary fibrosis in rats2013
- Author(s)
  Hori, M., Juniantito, V., Izawa, T., Ichikawa, C., Tanaka, M., Tanaka, K., Takenaka, S., Kuwamura, M., Yamate, J
- Journal Title
  
  J Comp Pathol
  
  Volume: 148 Issue: 4 Pages: 385-395
- DOI
  10.1016/j.jcpa.2012.09.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380173, KAKENHI-PROJECT-23658265
[Journal Article] Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: a possible marker of hair follicle development.2013
- Author(s)
  Ichikawa C, Izawa T, Juniantito V, Tanaka M, Hori M, Tanaka K, Takenaka S, Kuwamura M, Yamate J.
- Journal Title
  
  Histol Histopathol.
  
  Volume: 28 Pages: 257-268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658265
[Journal Article] Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody : a possible marker of hair follicle development2013
- Author(s)
  Ichikawa, C., Izawa, T., Juniantito, V., Tanaka, M., Hori, M., Tanaka, K., Takenaka, S., Kuwamura, M., Yamate, J
- Journal Title
  
  Histol Histopathol
  
  Volume: 28 Pages: 257-268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658265
[Journal Article] Distribution of Cells Labelled by a Novel Somatic Stem Cell-recognizing Antibody (A3) in Pulmonary Genesis and Bleomycin induced Pulmonary Fibrosis in Rats.2012
- Author(s)
  Hori M, Juniantito V, Izawa T, Ichikawa C, Tanaka M, Tanaka K, Takenaka S, Kuwamura M, Yamate J.
- Journal Title
  
  J Comp Pathol.
  
  Volume: 147 Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658265
[Journal Article] A general expression of the polarization factor for multi-diffraction processes.2010
- Author(s)
  Tanaka K, Takenaka Y, Funahashi S, Sakakura T, Komori T
- Journal Title
  
  Acta Crystallogr.A.
  
  Volume: 66 Pages: 438-440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510054
[Journal Article] A general express ionof the polarization factor for multi-diffracti on processes.2010
- Author(s)
  S. Takenaka, 他4名2番目
- Journal Title
  
  Acta Crystallogr. A 66
  
  Pages: 438-440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510054
[Journal Article] Metabolic Fingerprinting in Toxicological Assessment using FT-ICR MS2010
- Author(s)
  S. Takenaka, 他4名5番目
- Journal Title
  
  J.Toxicol.Pathol 23(2)
  
  Pages: 67-74
- NAID
  10030978709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510054
[Journal Article] Participation of functionally-different macrophage populations and monocyte chemoattractant protein-1 in early stages of thioacetamide-induced rat hepatic injury2009
- Author(s)
  Mori Y, Izawa T, Takenaka S, Kuwamura M and Yamate J.
- Journal Title
  
  Toxicol Pathol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380188
[Journal Article] Participation of functionally-different macrophage populations and monocyte chemoattractant protein-1 in early stages of thioacetamide-induced rat hepatic injury.2009
- Author(s)
  Mori Y, Izawa T, Takenaka S, Kuwamura M, Yamate J
- Journal Title
  
  Toxicol Pathol 37(4)
  
  Pages: 463-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380188
[Journal Article] Adipogenic, osteogenic and myofibrogenic differentiations of a rat malignant fibrous histiocytoma (MFH)-derived cell line, and a relationship of MFH cells with embryonal mesenchymal, perivascular and bone marrow stem cells.2007
- Author(s)
  Yamate J, Ogata K, Yuasa T, Kuwamura M, Takenaka S, Kumagai D, Itoh K, LaMarre J
- Journal Title
  
  Eur J Cancer 43(18)
  
  Pages: 2747-2756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380188
[Journal Article] Adipogenic, osteogenic and myofibrogenic differentiations of a rat malignant fibrous histiocytoma (MFH)-derived cell line, and a relationship of MFH cells with embryonal mesenchymal, perivascular and bone marrow stem cells2007
- Author(s)
  Yamate J, Ogata K, Yuasa T, Kuwamura M, Takenaka S, Kumagai D, Itoh K and LaMarre J.
- Journal Title
  
  Eur J Cancer. 43(18)
  
  Pages: 2747-2756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380188
[Presentation] 先天性ビタミンB12代謝異常症原因遺伝子cblB RNAiによるヒト神経芽腫細胞の代謝変動2023
- Author(s)
  溝端早紀，高松愛梨，中野寧々，松村成暢，叶内宏明，竹中重雄
- Organizer
  日本栄養食糧学会近畿支部大会
- Data Source
  KAKENHI-PROJECT-21K11649
[Presentation] 先天性ビタミンB12代謝異常症原因遺伝子群RNAiによるヒト神経芽細胞腫の分化抑制2022
- Author(s)
  高松愛梨，岡本彩希，松村成暢，岩城俊雄，叶内宏明，竹中重雄
- Organizer
  日本ビタミン学会
- Data Source
  KAKENHI-PROJECT-21K11649
[Presentation] Serum Metabolic Profiling of Rat Fed Folate and Vitamin B12 Depleted Diet2022
- Author(s)
  Takenaka, S., Natsuhara, M., Fujita, K., Okamoto, S., Matsumura, S., Iwaki, T., Kanouchi, H.,Tanaka, M., Izawa, T., Kuwamura, M.
- Organizer
  International Conference of Nutrition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11649
[Presentation] 全脳虚血後の海馬グリア細胞におけるSmadの発現とその活性について2020
- Author(s)
  中島崇行、髙橋勇祐、竹中重雄
- Organizer
  日本解剖学会
- Data Source
  KAKENHI-PROJECT-18K08862
[Presentation] 全脳虚血後の海馬グリア細胞におけるSmadの発現とその活性について2020
- Author(s)
  中島崇行、髙橋勇祐、竹中重雄
- Organizer
  第125回日本解剖学会
- Data Source
  KAKENHI-PROJECT-18K08862
[Presentation] The Expression and Activation of Smad proteins in Glial Cells of the Rat Hippocampus After Transient Global Cerebral Ischemia2019
- Author(s)
  Yusuke Takahashi, Shigeo Takenaka and Takayuki Nakajima
- Organizer
  7th Congress for Asian Association of Veterinary Anatomists (AAVA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08862
[Presentation] 虚血性プレコンディショニング後のラット海馬CA1領域におけるタンパク質発現の変化2017
- Author(s)
  中島崇行、竹中重雄
- Organizer
  日本病態生理学会
- Data Source
  KAKENHI-PROJECT-15K10520
[Presentation] 食餌による葉酸とビタミンB12欠乏モデルマウス作製の試み2017
- Author(s)
  小栁友和、平岩　悟、小森雅之、竹中重雄
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07770
[Presentation] CRISPR/Cas9法によるビタミンB12代謝関連遺伝子ノックアウト細胞作製2017
- Author(s)
  平岩　悟、小栁友和、小森雅之、竹中重雄
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-15K07770
[Presentation] ビタミンB12代謝異常がヒト慢性骨髄性白血病細胞の分化に及ぼす影響2017
- Author(s)
  巨海竜一、平岩　悟、小柳友和、小森雅之、竹中重雄
- Organizer
  日本ビタミン学会第69回大会
- Data Source
  KAKENHI-PROJECT-15K07770
[Presentation] ヒト神経芽腫細胞SH-SY5YにおけるビタミンB12代謝異常と酸化ストレス2016
- Author(s)
  竹中重雄，山木隆裕，巨海竜一，小森雅之
- Organizer
  日本ビタミン学会
- Place of Presentation
  富山国際会議場
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K07770
[Presentation] ビタミンB12代謝異常と低酸素による慢性骨髄性白血病細胞分化への影響2016
- Author(s)
  海竜一，平岩悟，小柳友和，小森雅之，竹中重雄
- Organizer
  日本獣医学会
- Place of Presentation
  日本大学資源科学部（湘南キャンパス）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-15K07770
[Presentation] 虚血性プレコンディショニング後のラット海馬におけるタンパク質発現の変化2015
- Author(s)
  中島崇行、竹中重雄
- Organizer
  第１５８回日本獣医学会
- Place of Presentation
  北里大学獣医学部（青森県十和田市）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-15K10520
[Presentation] Abundance of BER-related proteins depends on cell proliferation status and the presence of DNA polymerase β2015
- Author(s)
  Yamamoto, M., Yamamoto, R., Takenaka, S., Matsuyama, S. and Kubo, K.
- Organizer
  15th international congress of radiation research
- Place of Presentation
  国立京都国際会館（京都市左京区）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25340036
[Presentation] メチル化剤がマウスMPGの物理的相互作用に及ぼす影響の検討2015
- Author(s)
  山本瑞樹、松山聡、久保喜平、山本亮平、竹中重雄
- Organizer
  日本放射線影響学会ワークショップ
- Place of Presentation
  富山大学黒田講堂（富山市）
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-25340036
[Presentation] ビタミンB12代謝異常と酸化ストレスのヒト神経芽腫細胞への影響2015
- Author(s)
  山木隆裕，巨海竜一，小森雅之，竹中重雄
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K07770
[Presentation] 先天性ビタミンB12代謝異常症遺伝子群RNAiによるヒト神経芽腫細胞の分化抑制2015
- Author(s)
  山木隆裕、馬場雄大、巨海竜一、小森雅之、竹中重雄、渡辺文雄、中野長久
- Organizer
  日本ビタミン学会第66回大会
- Place of Presentation
  奈良県新公会堂（奈良県奈良市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15K07770
[Presentation] ビタミンB12代謝遺伝子RNAiはヒト神経芽腫細胞のストレス感受性を増加させる2015
- Author(s)
  山木隆裕、巨海竜一、小森雅之、竹中重雄
- Organizer
  第158回日本獣医学会学術集会
- Place of Presentation
  北里大学獣医学部（青森県十和田市）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-15K07770
[Presentation] ラット海馬CA1領域とCA3/DG領域間で発現レベルが異なるタンパク質のプロテオーム解析による探索2015
- Author(s)
  中島崇行、竹中重雄
- Organizer
  第２５回日本病態生理学会
- Place of Presentation
  愛媛大学（愛媛県松山市）
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-15K10520
[Presentation] ラット脳におけるビタミンB12とB12依存酵素メチルマロニルCoAムターゼとメチオニンシンターゼの日内変動2013
- Author(s)
  梶村　俊介，伊佐　桃子，森田大樹，馬場雄大，田舞理央、小森雅之，竹中重雄
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24580428
[Presentation] アデノシルコバラミン合成酵素RNAiによる2013
- Author(s)
  森田大樹、田舞理央、梶村俊介、馬場雄大、小森雅之、竹中重雄
- Organizer
  日本獣医学会第156回学術集会
- Place of Presentation
  岐阜大学
- Data Source
  KAKENHI-PROJECT-24580428
[Presentation] ラット脳における補酵素型ビタミンB12の日内変化2013
- Author(s)
  竹中重雄、伊佐桃子、梶村俊介、森田大樹、田舞理央、田中勝啓、小森雅之、桂博美、渡辺文雄、中野長久
- Organizer
  日本ビタミン学会　第65回大会
- Place of Presentation
  一橋大学・一橋講堂
- Data Source
  KAKENHI-PROJECT-24580428
[Presentation] ビタミンB12代謝異常症原因遺伝子MMABノックダウンによる細胞代謝への影響2012
- Author(s)
  竹中重雄, 楠本一仁, 鈴來佑介, 角田真穂, 伊佐桃子, 田舞理央, 田中勝啓, 小森雅之, 渡辺文雄, 中野長久
- Organizer
  日本ビタミン学会
- Place of Presentation
  長良川国際会議場
- Data Source
  KAKENHI-PROJECT-24580428
[Presentation] ラット体性幹細胞標識抗体A3 が認識する毛発生過程における上皮細胞の特性解明2012
- Author(s)
  市川智彩, 井澤武史, 田中勝啓, 竹中重雄, 桑村充, 山手丈至
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] ラット体性幹細胞標識抗体A3が認識する毛発生過程における上皮細胞の特性解明 .2012
- Author(s)
  市川智彩、井澤武史、田中勝啓、竹中重雄、桑村充、山手丈至
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-23658265
[Presentation] DNA塩基損傷修復酵素MPGと関連タンパク質の相互作用の検討2010
- Author(s)
  橋平奈穂子、山本瑞希、山本亮平、竹中重雄、松山聡、久保喜平
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都
- Year and Date
  2010-10-21
- Data Source
  KAKENHI-PROJECT-20510054
[Presentation] Macrophage appearance and monocyte chemoattractant protein-1 in thioacetamide-induced rat hepatic injury.2008
- Author(s)
  Yamate J, Mori Y, zawa T, Takenaka S, Kuwamura M
- Organizer
  The 27th Annual Meeting of the Society of Toxicologic Pathology (STP)
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-18380188
[Presentation] Macrophage appearance and monocyte chemoattractant protein-1 in thioacetamide-induced rat hepatic injury2008
- Author(s)
  Yamate J, Mori Y, zawa T, Takenaka S and Kuwamura M.
- Organizer
  The 27th Annual Meeting of the Society of Toxicologic Pathology (STP)
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-18380188
[Presentation] Proteomic analysis of the molecular basis of the ischemic tolerance in the rat hippocampus
- Author(s)
  中島崇行　竹中重雄
- Organizer
  第１２０回日本解剖学会
- Place of Presentation
  神戸国際会議場・展示場
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-24592314
[Presentation] Methypurine DNA glycosylaseとその関連タンパク量は細胞の増殖状態およびDNA polymerase βの有無に影響される
- Author(s)
  山本瑞希、山本亮平、竹中重雄、松山聡、久保喜平
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  かごしま県民交流センター（鹿児島県・鹿児島市）
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-25340036
[Presentation] 犬のリンパ腫における血清代謝物プロファイル
- Author(s)
  田舞理央、竹中重雄、他9名
- Organizer
  獣医内科学アカデミー
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-02-20 – 2015-02-21
- Data Source
  KAKENHI-PROJECT-24580428
[Presentation] 細胞の増殖状態およびDNA polymerase β（Polβ）の存在が他のBER関連タンパク量に与える影響
- Author(s)
  山本瑞希、山本亮平、竹中重雄、松山聡、久保喜平
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学（北海道・札幌市）
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25340036
[Presentation] アデノシルコバラミン合成酵素RNAiによる神経細胞の分化抑制
- Author(s)
  竹中重雄、森田大樹、馬場雄太、田舞理央、小森雅之、渡辺文雄、中野長久
- Organizer
  日本ビタミン学会
- Place of Presentation
  姫路商工会議所
- Year and Date
  2014-06-13 – 2014-06-14
- Data Source
  KAKENHI-PROJECT-24580428
[Presentation] 先天性ビタミンB12代謝異常症遺伝子群のRNAiによるヒト神経芽細胞腫の分化抑制
- Author(s)
  馬場雄大、山木降裕、田舞理央、小森雅之、竹中重雄
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-24580428

1. KUWAMURA Mitsuru (20244668)

# of Collaborated Projects: 7 results

# of Collaborated Products: 12 results
2. YAMATE Jyoji (50150115)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
3. IZAWA Takeshi (20580369)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
4. TAKAYUKI Nakajima (30333644)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
5. OHTA Daisaku (10305659)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. YAMAMOTO Ryouhei (20457998)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. TAMURA Yoshiyuki (40105036)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NAKAYAMA Rei (00189086)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KUBO Kihei (40117619)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
10. AKIYOSHI Shigeyasu (50420740)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 近藤友宏 (40585238)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. IWASAKI Tadashi (70336808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MATUYAMA Satoshi (10254442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. Hatoya Shingo (40453138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. NAKANISHI Mahito (10172355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. HISASUE Masaharu (80333144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Watanabe Kaori (30281273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 山中博之 (00085656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 杉浦喜久弥 (30171143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 桑原晶子 (00582602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 川村千恵子 (20281272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 岩城俊雄 (20295728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Takenaka Shigeo 竹中 重雄

TAKENAKA Shigeo 竹中 重雄

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Function of Vitamin B12 in BrainPrincipal Investigator

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Vitamin B12 metabolism and its relation for neural and cognitive functionsPrincipal Investigator

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Function of vitamin B12 on neural cell differentiation and an insight on cognitive symptom.Principal Investigator

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Takenaka Shigeo 竹中重雄

TAKENAKA Shigeo 竹中重雄