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AKIYOSHI Shigeyasu  秋吉 秀保

ORCIDConnect your ORCID iD *help
… Alternative Names

秋吉 秀保  アキヨシ ヒデオ

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Researcher Number 50420740
Other IDs
Affiliation (based on the past Project Information) *help 2022 – 2023: 大阪公立大学, 大学院獣医学研究科, 教授
2022: 大阪公立大学, 生命環境科学研究科, 教授
2017 – 2021: 大阪府立大学, 生命環境科学研究科, 教授
2011 – 2016: 大阪府立大学, 生命環境科学研究科(系), 准教授
2013: 大阪府立大学, 生命環境科学研究科, 准教授 … More
2011: 大阪府立大学, 生命環境科学研究科, 准教授
2010: 大阪府立大学, 生命環境科学研究科, 助教
2007: Osaka Prefecture University, 生命環境科学研究科, 助教
2006: 大阪府立大学, 生命環境科学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Clinical veterinary science
Except Principal Investigator
Basic Section 42020:Veterinary medical science-related / Veterinary medical science / Basic Section 52040:Radiological sciences-related / Veterinary medical science, Animal science, and related fields / Clinical veterinary science
Keywords
Principal Investigator
犬 / 抗体薬 / 分子標的薬 / キメラ抗体 / 分子標的治療薬 / リンパ腫 / バイオマーカー / クロモグラニンA / 腫瘍 / ストレス … More
Except Principal Investigator
… More 再生医療 / 間葉系幹細胞 / エクソソーム / 肝線維化 / 筋線維芽細胞 / マクロファージ / 腎線維化 / 画像検査 / 犬 / 分子イメージング / 網羅的遺伝子解析 / Radiogenomics / RNA sequence / CT / 肝細胞癌 / 獣医臨床 / 薬剤溶出性ビーズ / 伴侶動物 / バルーン閉塞下抗癌剤動注療法 / バルーン閉塞下動注化学療法 / 浸潤性膀胱癌 / 動物実験 / CDDP / バルーン閉塞下動注療法 / 膀胱癌 / 徐放化 / 抗炎症 / イヌ / ハイドロゲル / 徐放 / 脊髄損傷 / 細胞外小胞 / 臨床 / 脳・神経 / 移植・再生医療 / 抗炎症作用 / 分離 / 幹細胞 / トランスレーショナルリサーチ / 中枢神経再生 / アルツハイマー型認知症 / モデル動物 / 獣医薬理 / 凝集 / アミロイド / 不安 / GAPDHカスケード / ネコGAPDH / GAPDH / 老齢ネコ / ゲノム編集 / アルツハイマー病 / 難治性疾患 / 上皮‐間葉転換 / 臓器横断的解析 / 臓器横断的 / 皮膚線維化 / 線維化 / 病理学 / Galactin-3 / HSP25 / 創傷治癒線維化 / 抗原提示能 / カルポニン / Hsp25 / 皮膚創傷治癒 / 胆管周囲線維化 / 細胞骨格 / 抗原提示マクロファージ / 皮膚創傷治癒線維化 / 慢性腎臓病 / プロスタグランデン / 尿細管再生 / EMT / MHCクラスII / 誘導因子 Less
  • Research Projects

    (9 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (22 People)
  •  Contrast-enhanced CT as molecular imaging in canine hepatocellular carcinoma

    • Principal Investigator
      田中 利幸
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Osaka Metropolitan University
  •  Verification of Bladder Cancer Arterial Therapy under Balloon Occlusion and Development of a New Therapeutic Approach: Toward the Establishment of a Medical-Veterinary Cooperative Model

    • Principal Investigator
      Yamamoto Kiyohito
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
  •  Development of controlled release technology of stem cell-derived exosomes for spinal cord injury

    • Principal Investigator
      Nishida Hidetaka
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Osaka Metropolitan University
      Osaka Prefecture University
  •  Development of a new model of cat GAPDH knock-in Alzheimer's disease mice by the latest genome editing method

    • Principal Investigator
      Nakajima Hidemitsu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Veterinary medical science, Animal science, and related fields
    • Research Institution
      Osaka Prefecture University
  •  Development of method for central nervous regeneration using stem cell-derived exosomes

    • Principal Investigator
      Nishida Hidetaka
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Osaka Prefecture University
      Gifu University
  •  Based on the axis between macrophages and myofibroblasts, the organ-cross pathogenesis of incurable fibrosis

    • Principal Investigator
      Yamate Jyoji
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Osaka Prefecture University
  •  Development of novel molecular targeted therapy in canine malignant lymphomaPrincipal Investigator

    • Principal Investigator
      AKIYOSHI Hideo
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Clinical veterinary science
    • Research Institution
      Osaka Prefecture University
  •  The pathogenesis of progressive chronic renal disease and therapeutic strategies, based on the axis of macrophages and myofibroblasts

    • Principal Investigator
      YAMATE Jyoji
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Clinical veterinary science
    • Research Institution
      Osaka Prefecture University
  •  犬におけるストレス・腫瘍診断マーカーとしてのクロモグラニンAに関する研究Principal Investigator

    • Principal Investigator
      秋吉 秀保
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      Clinical veterinary science
    • Research Institution
      Osaka Prefecture University

All 2022 2021 2020 2019 2018 2007

All Journal Article Presentation

  • [Journal Article] Case Report: Detection of Transferrin in a Dog Suspected of Having Cerebrospinal Fluid Rhinorrhea2022

    • Author(s)
      Kinoshita Kosuke、Nishida Hidetaka、Kanegi Ryoji、Nakamoto Yuya、Tanaka Toshiyuki、Shimamura Shunsuke、Kusumoto Kazuhito、Akiyoshi Hideo
    • Journal Title

      Frontiers in Veterinary Science

      Volume: 9 Pages: 845809-845809

    • DOI

      10.3389/fvets.2022.845809

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06405, KAKENHI-PROJECT-21K14974
  • [Journal Article] Spinal epidural empyema concurrent with sequestrum in a cat: a case report2022

    • Author(s)
      Kosuke Kinoshita, Hidetaka Nishida, Ryoji Kanegi, Yuya Nakamoto, Toshiyuki Tanaka, Tamiko Fumimoto, Mitsuru Kuwamura, Yasuo Ogawa, Hideo Akiyoshi
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 84 Issue: 10 Pages: 1368-1372

    • DOI

      10.1292/jvms.22-0264

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K14974, KAKENHI-PROJECT-19K06405
  • [Journal Article] Controlled release of canine MSC-derived extracellular vesicles by cationized gelatin hydrogels2022

    • Author(s)
      Yoshizaki Karin, Nishida Hidetaka, Tabata Yasuhiko, Jo Junichiro, Nakase Ikuhiko, Akiyoshi Hideo.
    • Journal Title

      Regenerative Therapy

      Volume: 22 Pages: 1-6

    • DOI

      10.1016/j.reth.2022.11.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06405, KAKENHI-PROJECT-23K23789
  • [Journal Article] Extracellular Vesicles Derived From Canine Mesenchymal Stromal Cells in Serum Free Culture Medium Have Anti-inflammatory Effect on Microglial Cells2021

    • Author(s)
      Kuwahara Yukina、Yoshizaki Karin、Nishida Hidetaka、Kamishina Hiroaki、Maeda Sadatoshi、Takano Katsura、Fujita Naoki、Nishimura Ryohei、Jo Jun-ichiro、Tabata Yasuhiko、Akiyoshi Hideo
    • Journal Title

      Frontiers in Veterinary Science

      Volume: 8 Pages: 633426-633426

    • DOI

      10.3389/fvets.2021.633426

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06405
  • [Journal Article] Expression of microRNAs in plasma and in extracellular vesicles derived from plasma for dogs with glioma and dogs with other brain diseases.2020

    • Author(s)
      Narita M, Nishida H, Asahina R, Nakata K, Yano H, Dickinson PJ, Tanaka T, Akiyoshi H, Maeda S, Kamishina H.
    • Journal Title

      American Journal of Veterinary Research

      Volume: 81 Issue: 4 Pages: 355-360

    • DOI

      10.2460/ajvr.81.4.355

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06405
  • [Journal Article] Canine mesenchymal stromal cell-conditioned medium promotes survival and neurite outgrowth of neural stem cells2020

    • Author(s)
      Nakamura Michi, Nishida Hidetaka, Yoshizaki Karin, Akiyoshi Hideo, Hatoya Shingo, Sugiura Kikuya, Inaba Toshio
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 82 Issue: 5 Pages: 668-672

    • DOI

      10.1292/jvms.19-0141

    • NAID

      130007844440

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19274, KAKENHI-PROJECT-19K06405, KAKENHI-PROJECT-18H02349, KAKENHI-PROJECT-18K19273
  • [Journal Article] Identification of reference genes for microRNAs of extracellular vesicles isolated from plasma samples of healthy dogs by ultracentrifugation, precipitation, and membrane affinity chromatography methods2019

    • Author(s)
      Narita M, Nishida H, Asahina R, Nakata K, Yano H, Ueda T, Inden M, Akiyoshi H, Maeda S, Kamishima H
    • Journal Title

      American Journal of Veterinary Research

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15378
  • [Presentation] イヌ間葉系幹細胞由来Extracellular Vesicle徐放化技術を用いた治療法の開発2020

    • Author(s)
      吉﨑香琳、西田英高、三重慧一郎、城潤一郎、田畑泰彦、秋吉秀保
    • Organizer
      第10回DDS再生医療研究会
    • Data Source
      KAKENHI-PROJECT-19K06405
  • [Presentation] ゼラチンハイドロゲルを用いたイヌ間葉系幹細胞由来Extracellular Vesicle徐放化技術の開発2020

    • Author(s)
      吉﨑香琳、西田英高、三重慧一郎、城潤一郎、田畑泰彦、秋吉秀保
    • Organizer
      第19回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-19K06405
  • [Presentation] 無血清培地条件下で回収されたイヌ間葉系幹細胞由来Extracellular Vesicleの抗炎症効果2019

    • Author(s)
      吉崎香琳、桑原由季菜、西田英高、神志那弘明、前田貞俊、三重慧一郎、秋吉秀保
    • Organizer
      第162回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K06405
  • [Presentation] 無血清培地におけるイヌ骨髄間葉系幹細胞由来Extracellular Vesicleの回収法の検討2019

    • Author(s)
      吉﨑香琳、西田英高、桑原由季菜、三重慧一郎、秋吉秀保、城潤一郎、田畑泰彦
    • Organizer
      第18回日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-17K15378
  • [Presentation] Anti-inflammatory effect of extracellular vesicles derived from canine mesenchymal stem/stromal cells in serum free culture medium2019

    • Author(s)
      Yoshizaki K, Kuwahara Y, Nishida H, Kamishina H, Maeda S, Mie K, Akiyoshi H
    • Organizer
      The 6th Asian Meeting of Animal Medicine Specialties
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06405
  • [Presentation] Development of novel therapy for spinal cord injury using extracellular vesicles derived from mesenchymal stem/stromal cells in dogs2018

    • Author(s)
      Nishida H, Yoshiazaki K, Kuwahara Y, Mie K, Akiyoshi H
    • Organizer
      8th Annual Congress of Asia Society of Veterinary Surgery
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15378
  • [Presentation] 犬の頚部椎間板ヘルニアに対するMRI伸延撮像法の検討2018

    • Author(s)
      西田英高、中田浩平、山﨑緑、中野有希子、田中宏、中山正成、秋吉秀保、前田貞俊、神志那弘明
    • Organizer
      第 44 回獣医神経病学会
    • Data Source
      KAKENHI-PROJECT-17K15378
  • [Presentation] 幹細胞由来Extracellular Vesicleを用いた中枢神経治療法の開発2018

    • Author(s)
      西田英高、吉﨑香琳、桑原由季菜、三重慧一郎、秋吉秀保、Kim Dong-Ki、Prockop Darwin
    • Organizer
      第8回DDS再生医療研究会
    • Data Source
      KAKENHI-PROJECT-17K15378
  • [Presentation] 新しいストレスマーカー・腫瘍診断マーカー-小動物へのクロモグラニンAの応用-2007

    • Author(s)
      秋吉 秀保
    • Organizer
      第4回獣医内科学
    • Place of Presentation
      東京都新宿区
    • Year and Date
      2007-08-12
    • Data Source
      KAKENHI-PROJECT-18880023
  • 1.  YAMATE Jyoji (50150115)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  KUWAMURA Mitsuru (20244668)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  TAKANAKA Shigeo (10280067)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  IZAWA Takeshi (20580369)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  HATOYA Shingo (40453138)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  Nishida Hidetaka (00622804)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 7.  Nakajima Hidemitsu (30405360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MAEDA Sadatoshi (50377694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  KAMISHINA Hiroaki (50506847)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  Yamamoto Kiyohito (80779710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  田畑 泰彦 (50211371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 12.  城 潤一郎 (60511243)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 13.  大須賀 慶悟 (90332741)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  山本 和宏 (00288721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  中井 豪 (80388298)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  重里 寛 (80794768)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  松谷 裕貴 (80869587)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  三重 慧一郎 (30791082)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  前田 真一郎 (60452398)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  田中 利幸 (10833121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  野口 俊助 (10701295)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  Prockop Darwin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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