MIKI Yoshio 三木義男

… Alternative Names

三木義男ミキヨシオ

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Researcher Number	10281594
Other IDs
External Links
Affiliation (Current)	2025: 筑波大学, プレシジョン・メディスン開発研究センター, 客員教授
Affiliation (based on the past Project Information) *help	2002 – 2022: 東京医科歯科大学, 難治疾患研究所, 教授 2004 – 2006: (財)癌研究会, 癌研究所・遺伝子診断研究部, 部長 2003: Cancer Institute, Department of Genetic Diagnosis, Chief (Researcher), 癌研究会研究所・遺伝子診断部, 部長(研究職) 2003: 癌研究会研究所遺伝子診断部, 部長(研究職) 2002 – 2003: 癌研究会, 癌研究所・遺伝子診断部, 主任研究員 … More 2002: 癌研究会, 研究所・遺伝子診断部, 部長(研究職) 2001: 財団法人癌研究会, 癌研究所・遺伝子診断研究部, 部長 2000 – 2001: The Cancer Institute, Japanese Foundation for Cancer Research Dept. of Molecular Diagonosis, Chief, 癌研究所・遺伝子診断研究部, 部長 1999: 財団法人癌研究会, 癌研究所・遺伝子診断研究部, 部長 1999: 財団法人癌研究会, 癌研究所・遺伝子診断部, 部長 1998: Cancer Institute, Japanese Foundation for Cancer Research Dcpt. Molecular Diagonosis, Chief, 癌研究所・遺伝子診断研究部, 部長 1998: 癌研究会, 癌研究所遺伝子診断研究部, 部長 1997: 財団法人癌研究会, 癌研究所・遺伝子診断研究部, 部長 1997: 財団法人癌研究會, 癌研究所・遺伝子診断研究部, 部長 1996: 財団法人癌研究會, 癌化学療法センター・ゲノム解析研究部, 主任研究員 Less
Review Section/Research Field	Principal Investigator Complex systems / Tumor biology / Tumor biology / Biological Sciences / Basic Section 50010:Tumor biology-related / Medium-sized Section 50:Oncology and related fields / Tumor diagnostics / Human genetics / Pathological medical chemistry Except Principal Investigator Digestive surgery … More / Digestive surgery / Basic Section 63020:Radiation influence-related / Basic Section 50010:Tumor biology-related / Human genetics / Statistical science / Experimental pathology / Statistical science / General surgery / Obstetrics and gynecology Less
Keywords	Principal Investigator BRCA2 / 乳がん / BRCA1 / BRCA1/2 / がん抑制遺伝子 / 遺伝性乳癌 / 乳癌 / BRCA1, BRCA2 / DNA損傷修復 / Rad51 … More / PARP阻害剤 / 合成致死療法 / 癌 / がん / Two-hybrid法 / BRAP1 / beta-catenin / 癌抑制遺伝子 / 抗がん剤 / 合成致死 / MT1-MMP / 抗がん剤感受性 / 中心体 / 14-3-3 / 遺伝性乳がん / 乳腺発がん / DNA相同組換え修復機能 / BRCA1, 2 / BRCA2遺伝子 / BRCA1遺伝子 / DNA相同組換え修復 / 耐性克服療法 / 相同組み換え修復 / 合成致死量法 / 転写調節メカニズ / BRCA1・2 / 転写調節 / 転写調節メカニズム / MEN1 / ヒストンメチル化 / 転写調節機構 / MLL / Menin / オートファジー / Mfn / マイトファジー / ミトコンドリア / 遺伝子 / DNA 損傷修復 / BRCA遺伝子 / 治療感受性 / 遺伝子発現 / ゲノム / 治療効果予測 / 抗がん剤治療 / エストロゲン受容体α / エストロゲン受容体 / エストロゲン / APOPTOSIS / CYTOSKELETON / CYTOKINESIS / DNA DAMAGE REPAIR / HEREDITARY BREAST CANCER / BRCA2関連タンパク / 核移行シグナル / mel-18 / 臨床検査 / DNA損傷 / NTKL / RFX4 / RNAi法 / 遺伝子発現プロファイル / Two hybrid法 / アポトーシス / 細胞骨格 / 細胞分裂 / Two-hybrid method / Hereditary breast cancer / 遺伝子乳癌 / GSK-38 / TSG101 / H-cadherin / Tumor suppressor gene / Breast cancer / Mutation Screening / H-カドヘリン / 予後予測 / LOH / β-カテニン / H-ガドヘリン / エンドサイトーシス / ESCRT複合体 / エンドサイトーシ / 感受性規定因子 / 分子サブタイプ / BRCA1/BRCA2 / BRCA1/2遺伝子 / 化合物ライブラリー / 発がん / ゲノム安定性 / 遺伝子発現情報 / バイオインフォマティクス / ゲノム情報処理 / 乳がんの個性診断 / SiGN-BN / 主成分分析法 / クラスタリング / サブタイプ分類 / ユビキチン化 / 酸化ストレス / トポイソメラーゼIIα / 細胞死 / shRNAライブラリー / c-Ab1 / TAF1 / c-Abl / 細胞死誘導 / γ-チューブリン / 中心体移行シグナル / リン酸化BRCA2 / Plk1 / 中心体複製 / 核外移行シグナル / アポトーシス誘導 / 癌精巣抗原 / BJ-HCC-20A / NMHC IIC / Plectin / BRCA1,BRCA2 / 細胞質分裂 / 中心体制御 / DNA修復 / Two hybrid method / retrotransposal event / 家族性乳癌 … More Except Principal Investigator Aurora kinase B / BRCA2 / Paclitaxel / HIF-1α / Endostatin / Grb7 / Conexin 43 / G binding protein / alpha-1-B-adrenergic receptor / プロテオーム / 大腸癌 / SNP / 肝癌 / 既存薬再開発 / 多剤併用 / 化学療法抵抗性 / 合成致死 / 転写制御 / 相乗効果 / エトポシド / DNA損傷修復 / Tioxolone / PARP阻害剤 / ステロイド / トポイソメラーゼII阻害剤 / 相乗的抗腫瘍効果 / 化合物併用 / DNA二本鎖切断 / 化合物スクリーニング / 合成致死性 / 核輸送 / Importinβ / KPNA7 / 蛋白質 / 細胞・組織 / 遺伝学 / 癌 / BRCA / リサイクリングエンドソーム / 乳がん / False Discovery Rate / 多重検定法 / SNP解析 / 遺伝子発現解析 / クラスタリング / マイクロアレイ / 遺伝子間相互作用 / ゲノムワイド関連解析 / 多重検定 / Angiogenesis / Endogenous angiogenesis inhibitor / Metastatic tumor / Low-dose chemotherapy / 血管新生 / 内因性血管新生抑制分子 / 転移性がん / 低用量化学療法 / Iκkinase B / Molecular target / Recurrence / Pancreas cancer / Hepatocellular carcinoma / 分子標的剤 / ミラノ基準 / Array-CGH / cDNA Microarray / オミックス解析 / I κ kinase B / Molecular Target / 再発 / 膵臓癌 / 肝臓癌 / intestinal metaplasia / gastric cancer / MS-RDA / genome wide analysis / DNA methylation / colorectal cancer / 細胞増殖抑制能 / 若年大腸癌 / 異常メチル化 / 腸上皮化生 / 胃癌 / MS-RDA法 / 網羅的遺伝子検索 / DNAメチル化 / Machine Learning / Statistics / Clinical Information / Mass Spectrometry / Proteome / OMICSデータ / 統計的手法 / タンパク発現 / タンパク / 臨床 / 統計数学 / 機械学習 / 統計学 / 臨床情報 / 質量分析計 / hepatic hilar lymph node / liver resection / genetic diagnosis / colorectal liver metastasis / 転移性肝癌 / 肝門リンパ節 / 肝切除術式 / 遺伝子診断 / 大腸癌肝転移 / BRCA gene / Genetic test / Familial Breast Cancer / RET oncogene / Medullary Carcinoma / BRCA遺伝子 / 癌遺伝子検査 / 遺伝性乳癌 / RET癌遺伝子 / 甲状腺髄様癌 / radiosensitivity / microsatellite instability / Radiation induced colorectal cancer / 射線誘発大腸癌 / 遺伝子多型 / 放射線感受性 / マイクロサテライト不安定性 / 放射線誘発大腸癌 / predictive marker / 細胞アレイ / 薬剤耐性 / プラチナ製剤 / パクリタキセル / 上皮性卵巣癌 / トランスフェクションアレイ / 効果予測 / TC療法 / 上皮性卵巣がん / 婦人科腫瘍学 / CGHマイクロアレイ / cDNAアレイ / 門脈浸潤 / ゲノム不安定性 / 細胞分裂 / プロテアゾーム / stem cell marker / 癌幹細胞 / miRNA / Importin family / CYP1A2 / 分子標的治療 / 酸化ストレス / EpCAM / 幹細胞 / microRNA / DNAマイクロアレイ / 膵癌 / 充実型低分化腺癌(STPDC) / FLEP療法 / 予知指標 / 化学療法感受性 / 高度進行胃癌 Less

DNA修復分子の核内輸送機構を標的とする新たな合成致死がん治療の開発基盤研究
- Principal Investigator
  
  中西啓
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Medical and Dental University
Development of novel cancer treatment to overcome acquired resistance mechanisms in synthetic lethal therapy targeting DNA repair
- Principal Investigator
  
  Sunada Shigeaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Juntendo University
  Tokyo Medical and Dental University
Development of a Novel Synthetic Lethal Therapy for Breast Cancer by Targeting DNA Homologous Recombination Repair.Principal Investigator
- Principal Investigator
  
  Miki Yoshio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tokyo Medical and Dental University
Study on novel mechanism of breast cancer development by modulation of mitochondrial controlPrincipal Investigator
- Principal Investigator
  
  Miki Yoshio
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Tokyo Medical and Dental University
MLL-Menin-BRCA2複合体によるがん抑制機能ネットワークの解析Principal Investigator
- Principal Investigator
  
  三木義男
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Tokyo Medical and Dental University
システム的統合理解に基づく乳がん術前化学療法の応答性予測Principal Investigator
- Principal Investigator
  
  三木義男
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Medical and Dental University
Study on new treatment of breast cancer targeting BRCA gene functionPrincipal Investigator
- Principal Investigator
  
  MIKI Yoshio
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tokyo Medical and Dental University
遺伝性乳がん原因遺伝子産物ＢＲＣＡ２のリサイクリングエンドソームにおける機能解析
- Principal Investigator
  
  高岡美帆
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Medical and Dental University
Role of BRCA2 in the process of estrogen-dependent cell proliferationPrincipal Investigator
- Principal Investigator
  
  MIKI Yoshio
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor diagnostics
- Research Institution
  Tokyo Medical and Dental University
乳がん分子サブタイプの細胞機能特性の描出と個別化治療への展開Principal Investigator
- Principal Investigator
  
  三木義男
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Medical and Dental University
Elucidation of the new mechanism for breast carcinogenesis associated with early endosome.Principal Investigator
- Principal Investigator
  
  MIKI Yoshio
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Tokyo Medical and Dental University
Development of statistical methods for detecting gene-gene interactions from large-scale genomic data
- Principal Investigator
  
  USHIJIMA Masaru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Statistical science
- Research Institution
  Japanese Foundation for Cancer Research
Functional analysis of BRCA genes and searching for molecular partner for synthetic lethality.Principal Investigator
- Principal Investigator
  
  MIKI Yoshio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tokyo Medical and Dental University
乳癌の分子サブタイプ分類と個別化抗癌剤治療の開発Principal Investigator
- Principal Investigator
  
  三木義男
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Medical and Dental University
Analysis for a new mechanism of neoplastic cell transformation through the centrosome control with MT1-MMPPrincipal Investigator
- Principal Investigator
  
  MIKI Yoshio
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Tokyo Medical and Dental University
Establishment of gene scoring model to predict the effect of anticancer drug in ovarian cancer and the screening of the new molecular target
- Principal Investigator
  
  TSUDA Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Keio University
Study on the molecular diagnosis of metastasis and recurrence and molecular targeted therapy for intractable hepato-pancreatic cancer
- Principal Investigator
  
  ARII Shigeki
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University
Regulatory mechanisms of breast cancer cells in the apoptotic response to DNA damagePrincipal Investigator
- Principal Investigator
  
  MIKI Yoshio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
Multidisciplinary research for molecular mechanism of cancer progression and development of diagnostic and therapeutic tool
- Principal Investigator
  
  ARII Shigeki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University
Endostatin contributes to low-dose paclitaxel-mediated tumor growth and angiogenesis suppression
- Principal Investigator
  
  HAMANO Yuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Chiba University
Functional analysis of BRCA1 and BRCA2 on the mechanism of breast carcinogenesis.Principal Investigator
- Principal Investigator
  
  MIKI Yoshio
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Development of Statistical methodology for searching disease related factors based on proteomic and clinical information
- Principal Investigator
  
  MATSUURA Masaaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Statistical science
- Research Institution
  Japanese Foundation for Cancer Research
Genome wide analysis of DNA methylation in colorectal cancers in elderly and young patients
- Principal Investigator
  
  KONISHI Fumio
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Jichi Medical University
New Genetic Test and Surgery for Inherited Thyroid Garcinoma and Breast Cancer
- Principal Investigator
  
  TAKAMI Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Teikyo University
Genetic study on mode of tumor spread from colorectal metastasis in the liver -standardization of surgical procedure
- Principal Investigator
  
  KOKUDO Norihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
Genetic alterations in radiation-induced colorectal cancers and susceptibility to irradiation
- Principal Investigator
  
  ARAI Masami
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Japanese Foundation for Cancer Research
IDENTIFICATION AND FUNCTIONAL ANALYSES OF THE GENES RELATED TO HEREDITARY BREAST CANCERPrincipal Investigator
- Principal Investigator
  
  YOSHO Miki
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  TOKYO MEDICAL AND DENTAL UNIVERSITY
  Japanese Foundation For Cancer Research
胃癌の化学療法感受性の予知指標
- Principal Investigator
  
  KATO You
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Japanese Foundation For Cancer Research
Analysis of tumor suppressor genes for breast cancerPrincipal Investigator
- Principal Investigator
  
  MIKI Yoshio
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Japanese Foundation For Cancer Research
ヒト乳癌のおける癌抑制遺伝子の単離と遺伝子診断Principal Investigator
- Principal Investigator
  
  三木義男
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Japanese Foundation For Cancer Research
Analysis of genes related to human breast carcinogenesisPrincipal Investigator
- Principal Investigator
  
  MIKI Yoshino
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  Cancer Institute, Japanese Foundation for Cancer Research
ヒト乳癌における癌抑制遺伝子の単離と遺伝子診断Principal Investigator
- Principal Investigator
  
  三木義男
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Japanese Foundation For Cancer Research

[Book] がんの分子標的2008
- Author(s)
  磯村実, 三木義男
- Total Pages
  5
- Publisher
  遣伝子多型解析
- Data Source
  KAKENHI-PROJECT-19390083
[Book] がんの分子標的2008
- Author(s)
  磯村実、三木義男
- Total Pages
  5
- Publisher
  遺伝子多型解析
- Data Source
  KAKENHI-PROJECT-17013027
[Book] 消化器病学の進歩2005-モノグラフ- 消化管編2005
- Author(s)
  野田弘志, 小西文雄, 三木義男
- Total Pages
  276
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-16591348
[Journal Article] Discovery of novel DNA-damaging agents through phenotypic screening for DNA double-strand break2023
- Author(s)
  Zhang Doudou, Takashi Shimokawa, Qianqian Guo, Shingo Dan, Yoshio Miki, Shigeaki Sunada
- Journal Title
  
  Cancer Science
  
  Volume: 113(4) Issue: 3 Pages: 1108-1117
- DOI
  10.1111/cas.15659
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H04333
[Journal Article] BRCA2 represses the transcriptional activity of pS2 by E2-ERα.2022
- Author(s)
  Fukuda M, Tojo Y, Sato A, Saito H, Nakanishi A, Miki Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 588 Pages: 75-82
- DOI
  10.1016/j.bbrc.2021.12.054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03497
[Journal Article] The BRCA2 missense mutation K2497R suppressed self-degradation and increased ATP production and cell proliferation.2022
- Author(s)
  Enkhbat G, Nakanishi A, Miki Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 590 Pages: 27-33
- DOI
  10.1016/j.bbrc.2021.12.073
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03497
[Journal Article] 総論　遺伝性腫瘍総論2022
- Author(s)
  三木　義男
- Journal Title
  
  遺伝子医学【遺伝性腫瘍学入門　遺伝性腫瘍の基礎知識】
  
  Volume: 別冊 Pages: 22-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03497
[Journal Article] Regulation of Intrinsic Functions of PD-L1 by Post-Translational Modification in Tumors.2022
- Author(s)
  Nihira NT, Miki Y.
- Journal Title
  
  Front Oncol.
  
  Volume: 12 Pages: 825284-825284
- DOI
  10.3389/fonc.2022.825284
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03497, KAKENHI-PROJECT-20J40010
[Journal Article] Pathogenicity assessment of variants for breast cancer susceptibility genes based on BRCAness of tumor sample2021
- Author(s)
  Yoshida R, Hagio T, Kaneyasu T, Gotoh O, Osako T, Tanaka N, Amino S, Yaguchi N, Nakashima E, Kitagawa D, Ueno T, Ohno S, Nakajima T, Nakamura S, Miki Y, Hirota T, Takahashi S, Matsuura M, Noda T, Mori S.
- Journal Title
  
  Cancer Sci.
  
  Volume: 112(3) Issue: 3 Pages: 1310-1319
- DOI
  10.1111/cas.14803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03497, KAKENHI-PROJECT-18K07338, KAKENHI-PROJECT-18H04034, KAKENHI-PROJECT-19H01806, KAKENHI-PROJECT-21H02793, KAKENHI-PROJECT-19K07766
[Journal Article] CDK1 inhibitor controls G2/M phase transition and reverses DNA damage sensitivity.2021
- Author(s)
  Sunada S, Saito H, Zhang D, Xu Z, Miki Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 550 Pages: 56-61
- DOI
  10.1016/j.bbrc.2021.02.117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03497, KAKENHI-PROJECT-20H04333
[Journal Article] PARP Inhibitors: Mechanism of Action2021
- Author(s)
  Sunada Shigeaki、Miki Yoshio
- Journal Title
  
  Hereditary Breast and Ovarian Cancer
  
  Volume: 1 Pages: 281-292
- DOI
  10.1007/978-981-16-4521-1_18
- ISBN
  9789811645204, 9789811645211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04333
[Journal Article] Integrative cancer genomics in the era of precision cancer medicine.2021
- Author(s)
  Inazawa J, Miki Y, Nakamura Y.
- Journal Title
  
  J Hum Genet.
  
  Volume: 66 Issue: 9 Pages: 843-843
- DOI
  10.1038/s10038-021-00970-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03497
[Journal Article] Ultradeep targeted sequencing of circulating tumor DNA in plasma of early and advanced breast cancer2020
- Author(s)
  Chin Yoon Ming、Takahashi Yoko、Chan Hiu Ting、Otaki Masumi、Fujishima Makoto、Shibayama Tomoko、Miki Yoshio、Ueno Takayuki、Nakamura Yusuke、Low Siew‐Kee
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 1 Pages: 454-464
- DOI
  10.1111/cas.14697
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07709, KAKENHI-PROJECT-19H03497
[Journal Article] Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy2020
- Author(s)
  Gao Y, Nihira NT, Bu X, Chu C, Zhang J, Kolodziejczyk A, Fan Y, Chan NT, Ma L, Liu J, Wang D, Dai X, Liu H, Ono M, Nakanishi A, Inuzuka H, North BJ, Huang YH, Sharma S, Geng Y, Xu W, Liu XS, Li L, Miki Y, Sicinski P, Freeman GJ, Wei W.
- Journal Title
  
  Nat Cell Biol.
  
  Volume: 22(9) Issue: 9 Pages: 1064-1075
- DOI
  10.1038/s41556-020-0562-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03497, KAKENHI-PROJECT-19H03834
[Journal Article] Estradiol/GPER affects the integrity of mammary duct-like structures in vitro.2020
- Author(s)
  Deng Y, Miki Y*, Nakanishi A.
- Journal Title
  
  Sci Rep.
  
  Volume: 10 Issue: 1 Pages: 1386-1386
- DOI
  10.1038/s41598-020-57819-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04898, KAKENHI-PROJECT-18K19473, KAKENHI-PROJECT-19H03497
[Journal Article] 遺伝性腫瘍　遺伝子バリアント解釈の問題点2019
- Author(s)
  三木義男
- Journal Title
  
  腫瘍内科
  
  Volume: 24 Pages: 370-377
- Data Source
  KAKENHI-PROJECT-18K19473
[Journal Article] Germline pathogenic variants of 11 breast cancer genes in 7,051 Japanese patients and 11,241 controls.2019
- Author(s)
  Momozawa Y, Iwasaki Y, Parsons MT, Kamatani Y, Takahashi A, Tamura C, Katagiri T, Yoshida T, Nakamura S, Sugano K, Miki Y, Hirata M, Matsuda K, Spurdle AB, Kubo M.
- Journal Title
  
  Nat Commun.
  
  Volume: 9 Issue: 1 Pages: 4083-4083
- DOI
  10.1038/s41467-018-06581-8
- NAID
  120006949472
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19473, KAKENHI-PLANNED-17H06419, KAKENHI-PUBLICLY-18H04898, KAKENHI-PROJECT-16H04693, KAKENHI-PROJECT-16H05153, KAKENHI-PROJECT-17K19601, KAKENHI-PROJECT-17H03596
[Journal Article] Non-V600E BRAF mutations and EGFR signaling pathway in colorectal cancer.2019
- Author(s)
  Osumi H, Shinozaki E, Wakatsuki T, Suenaga M, Ichimura T, Ogura M, Takahari D, Ooki A, Suzuki T, Ota Y, Nakayama I, Chin K, Miki Y, Yamaguchi K.
- Journal Title
  
  Int J Cancer.
  
  Volume: 145 Issue: 9 Pages: 2488-2495
- DOI
  10.1002/ijc.32320
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04898, KAKENHI-PROJECT-19H03497, KAKENHI-PROJECT-18K19473
[Journal Article] Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population2019
- Author(s)
  Low Siew-Kee、Chin Yoon Ming、Ito Hidemi、Matsuo Keitaro、et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 17332-17332
- DOI
  10.1038/s41598-019-53654-9
- NAID
  120006875665
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K10037, KAKENHI-PROJECT-19K10655, KAKENHI-PROJECT-19K22525, KAKENHI-PLANNED-15H05908, KAKENHI-PLANNED-17H06419, KAKENHI-PUBLICLY-18H04898, KAKENHI-PROJECT-18H02688, KAKENHI-PROJECT-19H03497, KAKENHI-PROJECT-19H03881, KAKENHI-PROJECT-18K19473, KAKENHI-PROJECT-18K15332, KAKENHI-PROJECT-16H06277
[Journal Article] 遺伝性腫瘍　遺伝子バリアント解釈の問題点2019
- Author(s)
  三木義男
- Journal Title
  
  腫瘍内科
  
  Volume: 24 Pages: 370-377
- Data Source
  KAKENHI-PROJECT-19H03497
[Journal Article] 遺伝性腫瘍　遺伝子バリアント解釈の問題点2019
- Author(s)
  三木義男
- Journal Title
  
  腫瘍内科
  
  Volume: 24 Pages: 370-377
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Journal Article] Crosstalk of DNA double-strand break repair pathways in poly(ADP-ribose) polymerase inhibitor treatment of breast cancer susceptibility gene 1/2-mutated cancer.2018
- Author(s)
  Sunada S, Nakanishi A, Miki Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 109 Issue: 4 Pages: 893-899
- DOI
  10.1111/cas.13530
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19473, KAKENHI-PUBLICLY-18H04898, KAKENHI-PROJECT-16H04693, KAKENHI-PROJECT-17H06651
[Journal Article] BRCA1 gene: function and deficiency.2018
- Author(s)
  Takaoka M, Miki Y.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 23 Issue: 1 Pages: 36-44
- DOI
  10.1007/s10147-017-1182-2
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01570, KAKENHI-PROJECT-18K19473, KAKENHI-PUBLICLY-18H04898, KAKENHI-PROJECT-16H04693
[Journal Article] Phase II trial of biweekly cetuximab and irinotecan as third-line therapy for pretreated KRAS exon 2 wild-type colorectal cancer.2018
- Author(s)
  Osumi H, Shinozaki E, Mashima T, Wakatsuki T, Suenaga M, Ichimura T, Ogura M, Ota Y, Nakayama I, Takahari D, Chin K, Miki Y, Yamaguchi K
- Journal Title
  
  Cancer Sci.
  
  Volume: 109 Issue: 8 Pages: 2567-2575
- DOI
  10.1111/cas.13698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19473, KAKENHI-PUBLICLY-18H04898, KAKENHI-PROJECT-16H04693
[Journal Article] Detection of KRAS Mutations in Plasma DNA Using a fully Automated Rapid Detection System in Colorectal Cancer Patients.2017
- Author(s)
  Hosoya K, Matsusaka S, Kashiwada T, Suzuki K, Ureshino N, Sato A, Miki Y, Kitera K, Hirai M, Hatake K, Kimura S, Sueoka-Aragane N.
- Journal Title
  
  Pathol Oncol Res.
  
  Volume: 23 Issue: 4 Pages: 737-744
- DOI
  10.1007/s12253-016-0175-1
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01570, KAKENHI-PROJECT-16H04693
[Journal Article] Mutation status of RAD51C, PALB2 and BRIP1 in 100 Japanese familial breast cancer cases without BRCA1 and BRCA2 mutations.2017
- Author(s)
  Sato K, Koyasu M, Nomura S, Sato Y, Kita M, Ashihara Y, Adachi Y, Ohno S, Iwase T, Kitagawa D, Nakashima E, Yoshida R, Miki Y, Arai M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 108 Issue: 11 Pages: 2287-2294
- DOI
  10.1111/cas.13350
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01570, KAKENHI-PROJECT-16H04693
[Journal Article] FKBP51 regulates cell motility and invasion via RhoA signaling.2017
- Author(s)
  Takaoka M, Ito S, Miki Y, Nakanishi A.
- Journal Title
  
  Cancer Sci.
  
  Volume: 103 Issue: 3 Pages: 380-389
- DOI
  10.1111/cas.13153
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14394, KAKENHI-PROJECT-16K08639, KAKENHI-PUBLICLY-16H01570, KAKENHI-PROJECT-16H04693
[Journal Article] Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors.2016
- Author(s)
  Wang J, Ding Q, Fujimori H, Motegi A, Miki Y, Masutani M.
- Journal Title
  
  Oncotarget.
  
  Volume: 7 Issue: 7 Pages: 7701-7714
- DOI
  10.18632/oncotarget.6715
- NAID
  120005820856
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04693, KAKENHI-PROJECT-25340030, KAKENHI-PROJECT-15K14394
[Journal Article] BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein.2016
- Author(s)
  Malik S, Saito H, Takaoka M, Miki Y, Nakanishi A.
- Journal Title
  
  Cell Cycle
  
  Volume: 15 Pages: 2145-2156
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H04693
[Journal Article] BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein.2016
- Author(s)
  Malik S, Saito H, Takaoka M, Miki Y, Nakanishi A.
- Journal Title
  
  Cell Cycle.
  
  Volume: 15 Pages: 2145-2156
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14394
[Journal Article] BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein.2016
- Author(s)
  Malik S, Saito H, Takaoka M, Miki Y, Nakanishi A.
- Journal Title
  
  Cell Cycle
  
  Volume: 15 Pages: 2145-2156
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01570
[Journal Article] RAS mutation is a prognostic biomarker in colorectal cancer patients with metastasectomy.2016
- Author(s)
  Osumi H, Shinozaki E, Suenaga M, Matsusaka S, Konishi T, Akiyoshi T, Fujimoto Y, Nagayama S, Fukunaga Y, Ueno M, Mise Y, Ishizawa T, Inoue Y, Takahashi Y, Saiura A, Uehara H, Mun M, Okumura S, Mizunuma N, Miki Y, Yamaguchi T.
- Journal Title
  
  Int J Cancer
  
  Volume: Epub ahead of print Issue: 4 Pages: 803-811
- DOI
  10.1002/ijc.30106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14394, KAKENHI-PROJECT-15K10156
[Journal Article] RAS mutation is a prognostic biomarker in colorectal cancer patients with metastasectomy.2016
- Author(s)
  Osumi H, Shinozaki E, Suenaga M, Matsusaka S, Konishi T, Akiyoshi T, Fujimoto Y, Nagayama S, Fukunaga Y, Ueno M, Mise Y, Ishizawa T, Inoue Y, Takahashi Y, Saiura A, Uehara H, Mun M, Okumura S, Mizunuma N, Miki Y, Yamaguchi T.
- Journal Title
  
  Int J Cancer.
  
  Volume: 139 Pages: 803-811
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04693
[Journal Article] Prevalence and differentiation of hereditary breast and ovarian cancers in Japan.2015
- Author(s)
  Nakamura S, Takahashi M, Tozaki M, Nakayama T, Nomizu T, Miki Y, Murakami Y, Aoki D, Iwase T, Nishimura S, Yamauchi H, Ohsumi S, Baba S, Shimizu T.
- Journal Title
  
  Breast Cancer
  
  Volume: 22 Issue: 5 Pages: 462-8
- DOI
  10.1007/s12282-013-0503-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14394
[Journal Article] Periostin suppression induces decorin secretion leading to reduced breast cancer cell motility and invasion.2014
- Author(s)
  Ishiba T, Nagahara M, Nakagawa T, Sato T, Ishikawa T, Uetake H, Sugihara K, Miki Y, Nakanishi A.
- Journal Title
  
  Sci Rep
  
  Volume: 4 Issue: 1 Pages: 7069-7069
- DOI
  10.1038/srep07069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24300328, KAKENHI-PUBLICLY-25134709
[Journal Article] Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients.2014
- Author(s)
  Tan TZ, Miow QH, Miki Y, Noda T, Mori S, Huang RY, Thiery JP.
- Journal Title
  
  EMBO Mol Med.
  
  Volume: 6 Issue: 12 Pages: 1279-1293
- DOI
  10.4161/cc.28896
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24300328, KAKENHI-PUBLICLY-25134709, KAKENHI-PROJECT-25640061
[Journal Article] BRCA2 phosphorylated by PLK1 moves to the midbody to regulate cytokinesis mediated by nonmuscle myosin IIC.2014
- Author(s)
  Takaoka, Saito, Takenaka, Miki, and Nakanishi
- Journal Title
  
  Cancer Research
  
  Volume: 74 Issue: 5 Pages: 1518-1528
- DOI
  10.1158/0008-5472.can-13-0504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590355, KAKENHI-PROJECT-24300328, KAKENHI-PUBLICLY-25134709, KAKENHI-PROJECT-25640061
[Journal Article] Centrosomal BRCA2 is a target protein of membrane type-1 matrix metalloproteinase (MT1-MMP).2014
- Author(s)
  Wali N, Hosokawa K, Malik S, Saito H, Miyaguchi K, Imajoh-Ohmi S, Miki Y, Nakanishi A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 443 Issue: 4 Pages: 1148-1154
- DOI
  10.1016/j.bbrc.2013.12.103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300328, KAKENHI-PUBLICLY-25134709, KAKENHI-PROJECT-25640061
[Journal Article] Epithelial-mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients.2014
- Author(s)
  Tan TZ, Miow QH, Miki Y, Noda T, Mori S, Huang RY, Thiery JP.
- Journal Title
  
  EMBO Mol Med
  
  Volume: 6 Issue: 10 Pages: 1279-1293
- DOI
  10.15252/emmm.201404208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25134709
[Journal Article] Transforming mutations of RAC guanosine triphosphatases in human cancers2013
- Author(s)
  Kawazu, M., Ueno, T., Kontani, K., Ogita, Y., Ando, M., Fukumura, K., Yamato, A., Soda, M., Takeuchi, K., Miki, Y., Yamaguchi, H., Yasuda, T., Naoe, T., Yamashita, Y., Katada, T., Choi, Y.L. and Mano, H
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 110 Pages: 3029-34
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article]2013
- Author(s)
  Kawazu M, Ueno T, Kontani K, Ogita Y, Ando M, Fukumura K, Yamato A, Soda M, Takeuchi K, Miki Y, Yamaguchi H, Yasuda T, Naoe T,Yamashita Y, Katada T, Choi YL, Mano H,
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 110 Issue: 8 Pages: 3029-3034
- DOI
  10.1073/pnas.1216141110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300326, KAKENHI-PROJECT-23229001, KAKENHI-PROJECT-23370083, KAKENHI-PROJECT-23650592, KAKENHI-PROJECT-23689043, KAKENHI-PROJECT-24300328, KAKENHI-PROJECT-24657081, KAKENHI-PUBLICLY-23113706, KAKENHI-PUBLICLY-23121505, KAKENHI-PUBLICLY-23134503
[Journal Article] DYRK2 controls epithelial-mesenchymal transition in breast cancer by degrading Snail2013
- Author(s)
  Mimoto R, Taira N, Takahashi H, Yamaguchi T, Okabe M, Uchida K, Miki Y, Yoshida K
- Journal Title
  
  Cancer Lett
  
  Volume: 339 Issue: 2 Pages: 214-225
- DOI
  10.1016/j.canlet.2013.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300347, KAKENHI-PROJECT-24300328, KAKENHI-PUBLICLY-25134709, KAKENHI-PROJECT-25640080
[Journal Article] Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms2012
- Author(s)
  Sakamoto, K., Fujii, T., Kawachi, H., Miki, Y., Omura, K., Morita, K., Kayamori, K., Katsube, K. and Yamaguchi, A
- Journal Title
  
  Lab Invest
  
  Volume: 92 Pages: 688-702
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells2012
- Author(s)
  Taira, N., Mimoto, R., Kurata, M., Yamaguchi, T., Kitagawa, M., Miki, Y. and Yoshida, K
- Journal Title
  
  J Clin Invest
  
  Volume: 122 Pages: 859-72
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] ［がん種別の個別化治療の最前線］BRCA遺伝子と個別化治療2012
- Author(s)
  三木　義男
- Journal Title
  
  がん分子標的治療
  
  Volume: １０ Pages: 13-18
- Data Source
  KAKENHI-PUBLICLY-23134503
[Journal Article] A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese2012
- Author(s)
  Elgazzar, S., Zembutsu, H., Takahashi, A., Kubo, M., Aki, F., Hirata, K., Takatsuka, Y., Okazaki, M., Ohsumi, S., Yamakawa, T., Sasa, M., Katagiri, T., Miki, Y. and Nakamura, Y
- Journal Title
  
  J Hum Genet
  
  Volume: 57 Pages: 766-71
- NAID
  10031145883
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] Clinical impact of intraoperative detection of carcinoembryonic antigen mRNA in pleural lavage specimens from nonsmall cell lung cancer patients2012
- Author(s)
  Satoh, Y., Sugai, S., Uehara, H., Mun, M., Sakao, Y., Okumura, S., Nakagawa, K., Ishikawa, Y., Miki, Y. and Miyata, S
- Journal Title
  
  Thorac Cardiovasc Surg
  
  Volume: 60 Pages: 533-40
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with2012
- Author(s)
  Elgazzar S,
- Journal Title
  
  J Hum Genet
  
  Volume: 57 Issue: 12 Pages: 766-71
- DOI
  10.1038/jhg.2012.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650592, KAKENHI-PROJECT-24300328, KAKENHI-PROJECT-24300338, KAKENHI-PUBLICLY-23134503
[Journal Article] Expression of basal cell keratin 15 and keratin 19 in oral squamous neoplasms represents diverse pathophysiologies2012
- Author(s)
  Khanom, R., Sakamoto, K., Pal, S.K., Shimada, Y., Morita, K., Omura, K., Miki, Y. and Yamaguchi, A
- Journal Title
  
  Histol Histopathol
  
  Volume: 27 Pages: 949-59
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency2012
- Author(s)
  Wang L, Tsutsumi S, Kawaguchi T,Nagasaki K, Tatsuno K, Yamamoto S, SangF, Sonoda K, Sugawara M, Saiura A,Hirono S, Yamaue H, Miki Y, Isomura M,Totoki Y, Nagae G, Isagawa T, Ueda H,Murayama-Hosokawa S, Shibata T,Sakamoto H, Kanai Y, Kaneda A, Noda T,Aburatani H
- Journal Title
  
  Genome Research
  
  Volume: 22(2) Issue: 2 Pages: 208-19
- DOI
  10.1101/gr.123109.111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221009, KAKENHI-PROJECT-23650592, KAKENHI-PROJECT-23790775, KAKENHI-PROJECT-24300328, KAKENHI-PUBLICLY-23134503
[Journal Article] High level of miR-21, miR-10b, and miR-31 expression in bilateral vs.unilateral breast carcinomas2012
- Author(s)
  Iyevleva AG, Kuligina ESh, Mitiushkina NV, Togo AV, Miki Y, Imyanitov EN
- Journal Title
  
  Breast Cancer Res Treat
  
  Volume: 131 Pages: 1049-59
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23134503
[Journal Article] Programmed cell death 6, a novel p53-responsive gene, targets to the nucleus in the apoptotic response to DNA damage.2012
- Author(s)
  Kazuho Suzuki
- Journal Title
  
  Cancer Sci.
  
  Volume: 103 Issue: 10 Pages: 1788-1794
- DOI
  10.1111/j.1349-7006.2012.02362.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300347, KAKENHI-PROJECT-23650592, KAKENHI-PROJECT-23650612, KAKENHI-PROJECT-24300328, KAKENHI-PUBLICLY-23117515, KAKENHI-PUBLICLY-23134503
[Journal Article] Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency2012
- Author(s)
  Wang, L., Tsutsumi, S., Kawaguchi, T., Nagasaki, K., Tatsuno, K., Yamamoto, S., Sang, F., Sonoda, K., Sugawara, M., Saiura, A., Hirono, S., Yamaue, H., Miki, Y., Isomura, M., Totoki, Y., Nagae, G., Isagawa, T., Ueda, H., Murayama-Hosokawa, S., Shibata, T., Sakamoto, H., Kanai, Y., Kaneda, A., Noda, T. and Aburatani, H
- Journal Title
  
  Genome Res
  
  Volume: 22 Pages: 208-19
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] BRCA遺伝子と個別化治療.がん分子標的治療2012
- Author(s)
  三木義男
- Journal Title
  
  がん種別の個別化治療の最前線
  
  Volume: 10巻1号 Pages: 13-18
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms2012
- Author(s)
  Sakamoto K, Fujii T, Kawachi H, Miki Y, Omura K, Morita KI, Kayamori K, Katsube KI, Yamaguchi A
- Journal Title
  
  Laboratory investigation
  
  Volume: (Epub ahead of print) Issue: 5 Pages: 688-702
- DOI
  10.1038/labinvest.2012.9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592320, KAKENHI-PROJECT-22249061, KAKENHI-PROJECT-23592462, KAKENHI-PROJECT-23650592, KAKENHI-PROJECT-24300328, KAKENHI-PUBLICLY-23134503
[Journal Article] Programmed cell death 6, a novel p53-responsive gene, targets to the nucleus in the apoptotic response to DNA damage2012
- Author(s)
  Suzuki, K., Dashzeveg, N., Lu, Z.G.,Taira, N., Miki, Y. and Yoshida, K
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Pages: 1788-94
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells2012
- Author(s)
  Taira N, Mimoto R, Kurata M, Yamaguchi T, Kitagawa M, Miki Y, Yoshida K
- Journal Title
  
  J Clin Invest
  
  Volume: 122 Pages: 859-72
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23134503
[Journal Article] ［遺伝性乳癌卵巣癌診療の新時代］BRCA1とBRCA2遺伝子産物の機能　基礎から臨床2012
- Author(s)
  三木　義男
- Journal Title
  
  癌と化学療法
  
  Volume: 39 Pages: 498-501
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency2012
- Author(s)
  Wang L, …, Miki Y, …, Aburatani H
- Journal Title
  
  Genome Res
  
  Volume: 22 Pages: 208-19
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23134503
[Journal Article] Expression of basal eel 1 kerat in 15 and kerat in 19 in oral squamous neoplasms represents diverse pathophysiologies.2012
- Author(s)
  Khanom R, Sakamoto K, Pal SK, Shimada Y, MoritaK, Omura K, Miki Y, Yamaguchi A.
- Journal Title
  
  Histol Histopathol.
  
  Volume: 27 Pages: 949-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300328
[Journal Article] 乳癌の分子生物学と発癌機序発癌機序乳癌の発癌機序概論2012
- Author(s)
  斉藤広子,三木義男
- Journal Title
  
  乳癌(第2版)-基礎と臨床の最新研究動向-
  
  Volume: 70巻増刊7 Pages: 92-96
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] High level of miR-21, miR-10b, and miR-31 expression in bilateral vs. unilateral breast carcinomas.2012
- Author(s)
  Iyevleva AG,
- Journal Title
  
  Breast Cancer Res Treat.
  
  Volume: 13 Issue: 3 Pages: 1049-59
- DOI
  10.1007/s10549-011-1845-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650592, KAKENHI-PROJECT-24300328, KAKENHI-PUBLICLY-23134503
[Journal Article] DYRK2 priming phosphorylat ion of c-Jun and c-Myc modulates eell cycleprogression in human cancer cells.2012
- Author(s)
  Taira N, Mimoto R, Kurata M, Yamaguchi T, Kitagawa M, Miki Y, Yoshida K.
- Journal Title
  
  J Clin Invest.
  
  Volume: 122 Pages: 859-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300328
[Journal Article] 遺伝性乳癌卵巣癌診療の新時代2012
- Author(s)
  三木義男
- Journal Title
  
  BRCA1とBRCA2遺伝子産物の機能基礎から臨床.癌と化学療法
  
  Volume: 39巻4号 Pages: 498-501
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] High level of miR-21, miR-10b, and miR-31 expression in bilateral vs. unilateral breast carcinomas.2012
- Author(s)
  Iyevleva AG, Kuligina ESh, Mitiushkina NV, Togo AV, Miki Y, Imyanitov EN.
- Journal Title
  
  Breast Cancer Res Treat.
  
  Volume: 131 Pages: 1049-1059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] High level of miR-21, miR-10b, and miR-31 expression in bilateral vs. unilateral breast carcinomas2012
- Author(s)
  Iyevleva, A.G., Kuligina, E., Mitiushkina, N.V., Togo, A.V., Miki, Y. and Imyanitov, E.N
- Journal Title
  
  Breast Cancer Res Treat
  
  Volume: 131 Pages: 1049-59
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] ［遺伝性乳癌卵巣癌診療の新時代］BRCA1とBRCA2遺伝子産物の機能　基礎から臨床2012
- Author(s)
  三木　義男
- Journal Title
  
  癌と化学療法
  
  Volume: ３９ Pages: 498-501
- Data Source
  KAKENHI-PUBLICLY-23134503
[Journal Article] ［がん種別の個別化治療の最前線］BRCA遺伝子と個別化治療2012
- Author(s)
  三木　義男
- Journal Title
  
  がん分子標的治療
  
  Volume: 10 Pages: 13-18
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] BRCA2 and nucleophosmin coregulate centrosome amplification and form a complex with the Rho effector kinase ROCK22011
- Author(s)
  Wang HF, Takenaka K, Nakanishi A, Miki Y
- Journal Title
  
  Cancer Res
  
  Volume: 71 Pages: 68-77
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23134503
[Journal Article] BRCA2 and nucleophosmin coregulate centrosome amplification and form a complex with the Rho effector kinase ROCK2.2011
- Author(s)
  Wang HF, Takenaka K, Nakanishi A, Miki Y.
- Journal Title
  
  Cancer Res.
  
  Volume: 71 Pages: 68-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] PKCδ regulates Mdm2 independently of p53 in the apoptotic response to DNA damage2011
- Author(s)
  Hew HC, Liu H, Miki Y, Yoshida K
- Journal Title
  
  Mol Carcinog
  
  Volume: 50 Pages: 719-31
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23134503
[Journal Article] Gene expression signature of the gross morphology in hepatocellular carcinoma2011
- Author(s)
  Murakata A, Tanaka S, Mogushi K, YasenM, Noguchi N, Kudo A, Nakamura N, ItoK, Miki Y, Inazawa J, Tanaka H, AriiS
- Journal Title
  
  Annals of Surgery
  
  Volume: 253(1) Pages: 94-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249061
[Journal Article] Prospective randomized phase II study determines the clinical usefulness of genetic biomarkers for sensitivity to primary chemotherapy with paclitaxel in breast cancer.2011
- Author(s)
  Ito Y, Nagasaki K, Miki Y, Iwase T, Akiyama F, Matsuura M, Horii R, Makita M, Tokudome N, Ushijima M, Yoshimoto M, Takahashi S, Noda T, Hatake K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 130-6
- NAID
  10029288759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] PKCδ regulates Mdm2 independently of p53 in the apoptotic response to DNA damage.2011
- Author(s)
  Hew HC, Liu H, Miki Y, Yoshida K.
- Journal Title
  
  Mol Carcinog.
  
  Volume: 50 Pages: 719-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650592
[Journal Article] 7.Prospective randomized phase II study determines the clinical usefulness of genetic biomarkers for sensitivity to primary chemotherapy with paclitaxel in breast cancer2011
- Author(s)
  Ito Y, Nagasaki K, Miki Y, …, Hatake K
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 130-6
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23134503
[Journal Article] Gene expression phenotypes for vascular invasiveness of hepatocellular carcinomas.2010
- Author(s)
  Tanaka S, Mogushi K, Yasen M, Noguchi N, Kudo A, Nakamura N, Ito K, Miki Y, Inazawa J, Tanaka H, Arii S.
- Journal Title
  
  Surgery 147(3)
  
  Pages: 405-414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249061
[Journal Article] Gene-expression phenotypes for vascular invasiveness of hepatocellular carcinomas.2010
- Author(s)
  Tanaka S, Mogushi K, Yasen M, Noguchi N, Kudo A, Nakamura N, Ito K, Miki Y, Inazawa J, Tanaka H, Arii S.
- Journal Title
  
  Surgery. 147(3) Epub 2009 Nov 27.
  
  Pages: 405-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249061
[Journal Article] Gene expression phenotypes for vascular invasiveness of hepatocellular carcinomas2010
- Author(s)
  Tanaka S, Mogushi K, Yasen M, NoguchiN, Kudo A, Nakamura N, Ito K, Miki Y, Inazawa J, Tanaka H, Arii S
- Journal Title
  
  Surgery
  
  Volume: 147 Pages: 405-414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249061
[Journal Article] ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage.2009
- Author(s)
  Taira, N., Yamamoto, H., Yamaguchi, T., Miki, Y. *, Yoshida, K
- Journal Title
  
  J Biol Chem (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] DNA damage signalling recruits RREB-1 to the p53 tumour suppressor promoter.2009
- Author(s)
  Liu, H., Hew, H.C., Lu, Z.G., Yamaguchi, T., Miki, Y. *, Yoshida, K
- Journal Title
  
  Biochem J 422
  
  Pages: 543-51
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] BRCA2 interacts with the cytoskeletal linker protein plectin to form a complex controlling centrosome localization.2009
- Author(s)
  Niwa, T., Saito, H., Imajoh-ohmi, S., Kaminishi, M., Seto, Y., Miki, Y. *, Nakanishi, A
- Journal Title
  
  Cancer Sci 100
  
  Pages: 2115-25
- NAID
  10027197002
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates.2009
- Author(s)
  Takenaka, K., Miki, Y
- Journal Title
  
  FEBS Lett 583
  
  Pages: 661-4
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Abnormal collagen deposition in fibromas from patient with juvenile hyaline fibromatosis.2009
- Author(s)
  Tanaka K, Ebihara T, Kusubata M, Adachi E, Arai M, Kawaguchi N, Utsunomiya J, Miki Y, Hiramoto M, Hattori S, Irie S
- Journal Title
  
  J Dermatol Sci 55(3
  
  Pages: 197-200
- NAID
  10029371887
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Protein kinase Cdelta activates RelA/p65 and nuclear factor-kappaB signaling in response to tumor necrosis factor-alpha.2009
- Author(s)
  Lu, Z.G., Liu, H., Yamaguchi, T., Miki, Y. *, Yoshida, K.
- Journal Title
  
  Cancer Res 69
  
  Pages: 5927-35
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Pim-1 controls NF-kappaB signalling by stabilizing RelA/p652009
- Author(s)
  Nihira, K., Ando, Y., Yamaguchi, T., Kagami, Y., Miki, Y, Yoshida, K.
- Journal Title
  
  Cell Death Differ
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Molecular epidemiological and mutational analysis of DNA mismatch repair (MMR) genes in endometrial cancer patients with HNPCC-associated familial predisposition to cancer.2008
- Author(s)
  Hirai, Y., Banno, K., Suzuki, M., Ichikawa, Y., Udagawa, Y., Sugano, K., Miki, Y
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1715-9
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] IL12RB2 and ABCA1 genes are associated with susceptibility to radiation dermatitis.2008
- Author(s)
  Isomura, M., Oya, N., Tachiiri, S., Kaneyasu, Y., Nishimura, Y., Akimoto, T., Hareyama, M., Sugita, T., Mitsuhashi, N., Yamashita, T., Aoki, M., Sai, H., Hirokawa, Y., Sakata, K., Karasawa, K., Tomida, A., Tsuruo, T., Miki, Y., * Noda, T., Hiraoka, M
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 6683-9
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] BRCA1-mediated ubiquitination inhibits topoisomerase II alpha activity in response to oxidative stress.2008
- Author(s)
  Shinagawa, H., Miki, Y., * Yoshida, K.
- Journal Title
  
  Antioxid Redox Signal 10
  
  Pages: 939-49
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] BRCA1-mediated ubiquitination inhibits topoisomerase II alpha activity in response to oxidative stress2008
- Author(s)
  Shinagawa, H., Miki, Y.,*and Yoshida, K
- Journal Title
  
  Antioxid Redox Signal 10
  
  Pages: 939-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Aurora kinase B is a predictive factor for aggressive recurrence of hepatocellular carcinoma after curative hepatectomy2008
- Author(s)
  Tanaka S, Arii S, Yasen M, Mogusi K, Su N-T, Zhao C, Imoto I, Eishi Y, Inazawa J, Miki Y, Tanaka H
- Journal Title
  
  Brit J Surg
  
  Volume: 95 Pages: 61-619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249061
[Journal Article] Novel BRCA2-interacting protein BJ-HCC-20A inhibits the induction of apoptosis in response to DNA damage.2008
- Author(s)
  omiyoshi, G., Nakanishi, A., Takenaka, K., Yoshida, K., Miki, Y
- Journal Title
  
  Cancer Sci 99
  
  Pages: 747-54
- NAID
  10024004963
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] A Japanese patient with Li-Fraumeni syndrome who had nine primary malignancies associated with a germline mutation of the p53 tumor-suppressor gene2008
- Author(s)
  Izawa, N., Matsumoto, S., Manabe, J., Tanizawa, T., Hoshi, M., Shigemitsu, T., Machinami, R., Kanda, H., Takeuchi, K., Miki, Y., Arai, M., Shirahama, S., and Kawaguchi, N
- Journal Title
  
  Int J Clin Oncol 13
  
  Pages: 78-82
- NAID
  10024141710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Identification of novel deletion polymorphisms in breast cancer.2008
- Author(s)
  Komatsu, A., Nagasaki, K., Fujimori, M., Amano, J., Miki, Y
- Journal Title
  
  Int J Oncol 33
  
  Pages: 261-70
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Novel BRCA2-interacting protein BJ-HCC-20A inhibits the induction of apoptosis in response to DNA damage2008
- Author(s)
  Tomiyoshi, G., Nakanishi, A., Takenaka, K., Yoshida, K., and Miki, Y
- Journal Title
  
  Cancer Sci 99
  
  Pages: 747-54
- NAID
  10024004963
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] A CRM1-mediated nuclear export signal governs cytoplasmic localization of BRCA2 and is essential for centrosomal localization of BRCA2.2008
- Author(s)
  Han, X., Saito, H., Miki, Y., *, Nakanishi, A
- Journal Title
  
  Oncogene 27
  
  Pages: 2969-77
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Molecular prediction of the therapeutic response to neoadjuvant chemotherapy in breast cancer.2008
- Author(s)
  Nagasaki, K., Miki, Y
- Journal Title
  
  Breast Cancer 15
  
  Pages: 117-20
- NAID
  10025371689
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Aurora kinase B is a predictive factor for aggressive recurrence of hepatocellular carcinoma after curative hepatectomy.2008
- Author(s)
  Tanaka S, Arii S, Yasen M, Mogusi K, Su N-T, Zhao C, Imoto I, Eishi Y, Inazawa J, Miki Y, Tanaka H.
- Journal Title
  
  Brit J Surg 95
  
  Pages: 611-619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249061
[Journal Article] Identification of the molecular mechanisms for dedifferentiation at the invasion front of colorectal cancer by a gene expression analysis2008
- Author(s)
  Oku, Y., Shimoji, T., Takifuji, K., Hotta, T., Yokoyama, S., Matsuda, K., Higashiguchi, T., Tominaga, T., Nasu, T., Tamura, K., Matsuura, M., Miyata, S., Kato, Y., Yamaue, H., and Miki, Y
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 7215-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] A functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress.2008
- Author(s)
  Kimura, J., Nguyen, S.T., Liu, H., Taira, N., Miki, Y., *, Yoshida, K
- Journal Title
  
  Nucleic Acids Res 36
  
  Pages: 5250-9
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Molecular epidemiological and mutational analysis of DNA mismatch repair(MMR)genes in endometrial cancer patients with HNPCC-associated familial predisposition to cancer2008
- Author(s)
  Hirai, Y., Banno, K., Suzuki, M., Ichikawa, Y., Udagawa, Y., Sugano, K., and Miki, Y
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1715-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] A functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress2008
- Author(s)
  Kimura, J., Nguyen, S. T., Liu, H., Taira, N., Miki, Y.,*and Yoshida, K
- Journal Title
  
  Nucleic Acids Res 36
  
  Pages: 5250-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Recurrence pattern and rapid intraoperative detection of carcinoembryonic antigen(CEA)mRNA in pleural lavage in patients with non-small cell lung cancer(NSCLC)2008
- Author(s)
  Sugai, S., Satoh, Y., Komatsu, M., Okumura, S., Nakagawa, K., Ishikawa, Y., and Miki, Y
- Journal Title
  
  Rinsho Byori 56
  
  Pages: 851-7
- NAID
  10024960497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] TTK/Mps1 controls nuclear targeting of c-Abl by 14-3-3-coupled phosphorylation in response to oxidative stress2008
- Author(s)
  Nihira, K., Taira, N., Miki, Y.,*and Yoshida, K
- Journal Title
  
  Oncogene 27
  
  Pages: 7285-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] IL12RB2 and ABCA1 genes are associated with susceptibility to radiation dermatitis2008
- Author(s)
  Isomura, M., Oya, N., Tachiiri, S., Kaneyasu, Y., Nishimura, Y., Akimoto, T., Hareyama, M., Sugita, T., Mitsuhashi, N., Yamashita, T., Aoki, M., Sai, H., Hirokawa, Y., Sakata, K., Karasawa, K., Tomida, A., Tsuruo, T., Miki, Y.,* Noda, T., and Hiraoka, M
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 6683-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Aurora kinase B is a predictive factor for the aggressive recurrence of hepatocellular carcinoma after curative hepatectomy2008
- Author(s)
  Tanaka, S., Arii, S., Yasen, M., Mogushi, K., Su, N. T., Zhao, C., Imoto, I., Eishi, Y., Inazawa, J., Miki, Y., and Tanaka, H
- Journal Title
  
  Br J Surg 95
  
  Pages: 611-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Recurrence pattern and rapid intraoperative detection of carcinoembryonic antigen (CEA) mRNA in pleural lavage in patients with non-small cell lung cancer (NSCLC)2008
- Author(s)
  Sugai, S., Satoh, Y., Komatsu, M., Okumura, S., Nakagawa, K., Ishikawa, Y., Miki, Y
- Journal Title
  
  Rinsho Byori 56
  
  Pages: 851-7
- NAID
  10024960497
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Aurora kinase B is a predictive factor for aggressive recurrence of hepatocellular carcinoma after curative hepatectomy2008
- Author(s)
  Tanaka S, Arii S, Yasen M, Mogusi K, Su N-T, Zhao C, Imoto I, Eishi Y, Inazawa J, Miki Y, Tanaka H.
- Journal Title
  
  Brit J Surg 95
  
  Pages: 611-619
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18209043
[Journal Article] Identification of the molecular mechanisms for dedifferentiation at the invasion front of colorectal cancer by a gene expression analysis.2008
- Author(s)
  Oku, Y., Shimoji, T., Takifuji, K., Hotta, T., Yokoyama, S., Matsuda, K., Higashiguchi, T., Tominaga, T., Nasu, T., Tamura, K., Matsuura, M., Miyata, S., Kato, Y., Yamaue, H., Miki, Y
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 7215-22
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] TTK/Mps1 controls nuclear targeting of c-Abl by 14-3-3-coupled phosphorylation in response to oxidative stress.2008
- Author(s)
  Nihira, K., Taira, N., Miki, Y., * Yoshida, K
- Journal Title
  
  Oncogene 27
  
  Pages: 7285-95
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Cross-sectional analysis of germline BRCA1 and BRCA2 mutations in Japanese patients suspected to have hereditary breast/ovarian cancer.2008
- Author(s)
  Sugano, K., Nakamura, S., Ando, J.,Takayama, S., Kamata, H., Sekiguchi, I.,Ubukata, M., Kodama, T., Arai, M., Kasumi,F., Hirai, Y., Ikeda, T., Jinno, H.,Kitajima, M., Aoki, D., Hirasawa, A.,Takeda, Y., Yazaki, K., Fukutomi, T.,Kinoshita, T., Tsunematsu, R., Yoshida, T.,Izumi, M., Umezawa, S., Yagata, H.,Komatsu, H., Arimori, N., Matoba, N.,Gondo, N., Yokoyama, S., Miki, Y.
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1967-76
- NAID
  10024011931
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Aurora kinase B is a predictive factor for aggressive recurrence of hepa tocellular carcinoma after curative hepatectomy2008
- Author(s)
  Tanaka S, Arii S, Yasen M, Mogusi K, Su N-T, Zhao C, Imoto I, Eishi Y, Inazawa J, Miki Y, Tanaka H.
- Journal Title
  
  Brit J Surg 95
  
  Pages: 611-619
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209043
[Journal Article] A CRM1-mediated nuclear export signal governs cytoplasmic localization of BRCA2 and is essential for centrosomal localization of BRCA22008
- Author(s)
  Han, X., Saito, H., Miki, Y.,*and Nakanishi, A
- Journal Title
  
  Oncogene 27
  
  Pages: 2969-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Aurora kinase B is a predictive factor for the aggressive recurrence of hepatocellular carcinoma after curative hepatectomy.2008
- Author(s)
  Tanaka, S., Arii, S., Yasen, M., Mogushi, K., Su, N.T., Zhao, C., Imoto, I., Eishi, Y., Inazawa, J., Miki, Y., Tanaka, H
- Journal Title
  
  Br J Surg 95
  
  Pages: 611-9
- Data Source
  KAKENHI-PROJECT-17013027
[Journal Article] Cross-sectional analysis of germline BRCA1 and BRCA2 mutations in Japanese patients suspected to have hereditary breast/ovarian cancer2008
- Author(s)
  Sugano, K., Nakamura, S., Ando, J., Takayama, S., Kamata, H., Sekiguchi, I., Ubukata, M., Kodama, T., Arai, M., Kasumi, F., Hirai, Y., Ikeda, T., Jinno, H., Kitajima, M., Aoki, D., Hirasawa, A., Takeda, Y., Yazaki, K., Fukutomi, T., Kinoshita, T., Tsunematsu, R., Yoshida, T., Izumi, M., Umezawa, S., Yagata, H., Komatsu, H., Arimori, N., Matoba, N., Gondo, N., Yokoyama, S., and Miki, Y
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1967-76
- NAID
  10024011931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Molecular prediction of the therapeutic response to neoadjuvant chemotherapy in breast cancer2008
- Author(s)
  Nagasaki, K., and Miki, Y
- Journal Title
  
  Breast Cancer 15
  
  Pages: 117-20
- NAID
  10025371689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Frequent reduced expression of alpha-1B-adrenergic receptor caused by aberrant promoter methylation in gastric cancers2007
- Author(s)
  Noda H, Miyaji Y, Nakanishi A, Konishi F, Miki Y
- Journal Title
  
  Br J Cancer 96
  
  Pages: 383-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Histological features of breast cancer, highly sensitive to chemotherapy2007
- Author(s)
  Horii R, Akiyama F, Ito Y, Matsuura M, Miki Y, Iwase T
- Journal Title
  
  Breast Cancer 14
  
  Pages: 393-400
- NAID
  10019800584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Protein kinase C delta activates IkappaB-kinase alpha to induce the p53 tumor suppressor in response to oxidative stress2007
- Author(s)
  Yamaguchi T, Miki Y, * Yoshida K
- Journal Title
  
  Cell Signal 19
  
  Pages: 2088-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage2007
- Author(s)
  Taira N, Nihira K, Yamaguchi T, Miki Y, Yoshida K
- Journal Title
  
  Mol Cell 25
  
  Pages: 725-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma2007
- Author(s)
  Nguyen ST, Hasegawa S, Tsuda H, Tomioka H, Ushijima M, Noda M, Omura K, Miki Y
- Journal Title
  
  Cancer Sci 98
  
  Pages: 740-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage2007
- Author(s)
  Liu H, Lu ZG, Miki Y, * Yoshida K
- Journal Title
  
  Mol Cell Biol 27
  
  Pages: 8480-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Identifying haplotype block structure using an ancestor-derived model2007
- Author(s)
  Fujisawa H, Isomura M, Eguchi S, Ushijima M, Miyata S, Miki Y, Matsuura M
- Journal Title
  
  J Hum Gene 52
  
  Pages: 738-46
- NAID
  10019812610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Functional pathway characterized by gene expression analysis of supraclavicular lymph node metastasis-positive breast cancer2007
- Author(s)
  Oishi Y, Nagasaki K, Miyata S, Matsuura M, Nishimura S, Akiyama F, Iwai T, Miki Y
- Journal Title
  
  J Hum Genet 52
  
  Pages: 271-9
- NAID
  10018554326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] The Deubiquitinating Enzyme USP11 Controls an I{kappa}B Kinase{alpha}(IKK {alpha})-p53 Signaling Pathway in Response to Tumor Necrosis Factor{alpha}(TNF {alpha})2007
- Author(s)
  Yamaguchi T, Kimura J, Miki Y, * Yoshida K
- Journal Title
  
  J Biol Chem 282
  
  Pages: 33943-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Interference with BRCA2, which localizes to the centrosome during S and early M phase, leads to abnormal nuclear division2007
- Author(s)
  Nakanishi A, Han X, Saito H, Taguchi K, Ohta Y, Imajoh-Ohmi S, Miki Y
- Journal Title
  
  Biochem Biophys Res Commun 355
  
  Pages: 34-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Reduced Levels of ATF-2 Predispose Mice to Mammary Tumors2007
- Author(s)
  Maekawa T, Shinagawa T, Sano Y, Sakuma T, Nomura S, Nagasaki K, Miki Y, Saito-Ohara F, Inazawa J, Kohno T, Yokota J, Ishii S
- Journal Title
  
  Mol Cell Biol 27
  
  Pages: 1730-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Journal Article] Frequent reduced expression of alpha-1B-adrenergic receptor caused by aberrant promoter methylation in gastric cancers2007
- Author(s)
  Noda H, Miyaji Y, Nakanishi A, Konishi, Miki Y
- Journal Title
  
  British Journal of Cancer 96
  
  Pages: 383-390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591348
[Journal Article] Frequent Involvement of Ras-signalling Pathways in Both Polypoid-type and Flat-type Early-stage Colorectal2006
- Author(s)
  Noda H, Kato Y, Yoshikawa H, Arai M, Togashi K, Nagai H, Konishi F, Miki Y
- Journal Title
  
  J. Exp. Clin. Cancer Res 25
  
  Pages: 235-242
- Data Source
  KAKENHI-PROJECT-16591348
[Journal Article] Frequent Involvement of Ras-signalling Pathways in Both Polypoid-type and Flat-type Early-stage Colorectal2006
- Author(s)
  Noda H, Kato Y, Yoshikawa H, Arai M, Togashi K, Nagai H, Konishi F, Miki Y
- Journal Title
  
  J.Exp.Clin.Cancer Res 25-2
  
  Pages: 235-242
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591348
[Journal Article] Microsatellite Instability Caused by hMLH1 Promoter Methylation Increases with Tumor Progression in Right-Sided Sporadic Colorectal Cancer2005
- Author(s)
  Noda H, Kato Y, Yoshikawa H, Arai M, Togashi K, Nagai H, Konishi F, Miki Y
- Journal Title
  
  Oncology 69・4
  
  Pages: 354-362
- Data Source
  KAKENHI-PROJECT-16591348
[Journal Article] Microsatellite Instability Caused by hMLH1 Promoter Methylation Increases with Tumor Progression in Right-Sided Sporadic Colorectal Cancer2005
- Author(s)
  Noda H, Kato Y, Yoshikawa H, Arai M, Togashi K, Nagai H, Konishi F, Miki Y
- Journal Title
  
  Oncology 9-4
  
  Pages: 354-362
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591348
[Journal Article] JNK phosphorylation of 14-3-3 regulates nuclear targeting of c-Abl In the apoptotic response to DNA damage.2005
- Author(s)
  Yoshida, K., Yamaguchi, T., Natsume, T., Kufe, D., Miki Y.
- Journal Title
  
  Nat Cell Biol. 7
  
  Pages: 278-285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213141
[Journal Article] Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers.2004
- Author(s)
  Onda, M., Emi, M., Nagai, H., Nagahata, T., Tsumagari, K., Fujimoto, T., Akiyama, F., Sakamoto, G., Makita, M., Kasumi, F., Miki Y Tanaka, T., Tsunoda, T., Nakamura, Y.
- Journal Title
  
  J.Cancer Res.Clin.Oncol. 130
  
  Pages: 537-545
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213141
[Journal Article] Genome-wide gene-expression profiles of breast-cancer cells purified with laser microbeam microdissection : identification of genes associated with progression and metastasis.2004
- Author(s)
  Nishidate, T., Katagiri, T., Lin, M.L., Mano, Y., Miki.Y.Kasumi, F., Yoshimoto, M., Tsunoda, T., Hirata, K., Nakamura, Y.
- Journal Title
  
  Int J Oncol. 25
  
  Pages: 797-819
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213141
[Journal Article] Expression profiling to predict postoperative prognosis for estrogen receptor-negative breast cancers by analysis of 25,344 genes on a cDNA microarray.2004
- Author(s)
  Nagahata, T., Onda, M., Emi, M., Nagai, H., Tsumagari, K., Fujimoto, T., Hirano, A., Sato, T., Nishikawa, K., Akiyama, F., Sakamoto, G., Kasumi, F., Miki.Y..Tanaka, T., Tsunoda, T.
- Journal Title
  
  Cancer Sci. 95
  
  Pages: 218-225
- NAID
  10013721729
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213141
[Journal Article] Genotyping of Single Nucleotide Polymorphisms Based on a Mathematical Model for Two-Dimensional Data2004
- Author(s)
  Satoh K., Otani K., Ushijima M., Isomura M, Matsuura M., Miki Y., Ohtaki M.
- Journal Title
  
  計量生物学 25
  
  Pages: 61-67
- NAID
  10014334851
- Data Source
  KAKENHI-PROJECT-16300090
[Journal Article] Relatively common mutations of the Bloom syndrome gene in the Japanese population.2004
- Author(s)
  Kaneko, H., Isogai, K., Fukao, T., Matsui, E., Kasahara, K., Yachie, A., Seki, H., Koizumi, S., Arai, M., Utsunomiya, J., Miki.Y., Kondo, N.
- Journal Title
  
  Int.J.Mol.Med. 14
  
  Pages: 439-442
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213141
[Journal Article] Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage.2004
- Author(s)
  Yoshida, K., Miki. Y.
- Journal Title
  
  Cancer Sci. 95
  
  Pages: 866-871
- NAID
  10014197645
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213141
[Journal Article] Genotyping of single nucleotide polymorphism using model-based clustering.2004
- Author(s)
  Fujisawa, H., Eguchi, S., Ushijima, M., Miyata, S., Miki.Y., Muto, T., Matsuura, M.
- Journal Title
  
  Bioinformatics. 20
  
  Pages: 718-726
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213141
[Journal Article] Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage.2004
- Author(s)
  Yoshida, K., Miki, Y.
- Journal Title
  
  Cancer Sci. 95
  
  Pages: 866-871
- NAID
  10014197645
- Data Source
  KAKENHI-PROJECT-12213141
[Journal Article] Familial breast and ovarian cancers.2004
- Author(s)
  Arai, M., Utsunomiya, J., Miki.Y.
- Journal Title
  
  Int J Clin Oncol. 4
  
  Pages: 270-282
- NAID
  10013569457
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12213141
[Journal Article] Identification of novel deletion polymorphisms in breast cancer
- Author(s)
  Komatsu, A., Nagasaki, K., Fujimori, M., Amano, J., and Miki, Y
- Journal Title
  
  Int J Oncol 33
  
  Pages: 2008-2008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390083
[Patent] 悪性腫瘍治療剤2022
- Inventor(s)
  砂田成章, 三木義男
- Industrial Property Rights Holder
  砂田成章, 三木義男
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-144405
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20H04333
[Presentation] ステロイドはTop2毒を促進することでトポイソメラーゼ2阻害剤による細胞感受性を増強する(Steroids sensitize Top2 inhibitor treated tumor cells by potentiating Top2 poisons)2022
- Author(s)
  砂田成章, 趙ニン, 張抖抖, 三木義男
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PROJECT-20H04333
[Presentation] 臨床的意義不明なBRCA1/2バリアントの相同組み換え活性(Homologous Recombination Activity of BRCA1/2 VUSs)2022
- Author(s)
  郭倩倩, 姫しゅうてい, 斉藤広子, 三木義男, 砂田成章
- Organizer
  第81回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-20H04333
[Presentation] Elucidation of the BRCA2 nuclear transport system2021
- Author(s)
  Shiori Hirayama, Ami Sato, Yu Deng, Akira Nakanishi, Yoshio Miki
- Organizer
  第８０回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02759
[Presentation] 臨床的意義不明なBRCA2バリアントの相同組換え活性2021
- Author(s)
  郭倩倩, 徐澤宇, 斉藤広子, 砂田成章, 三木義男
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03497
[Presentation] PD-L1の核内移行制御に対する分子標的薬は抗PD抗体による癌免疫治療の効果を向上させる2021
- Author(s)
  仁平直江, 三木義男, Wei Wenyi
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03497
[Presentation] 遺伝性乳がん原因遺伝子BRCA2タンパク質の核輸送システムの解明2021
- Author(s)
  平山栞, 佐藤亜美, トウ・ウ , 中西啓, 三木義男
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03497
[Presentation] S期における中心体隣接の生理的役割2021
- Author(s)
  東條陽, 中西啓, 三木義男
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03497
[Presentation] 臨床的意義不明なBRCA2バリアントの相同組換え活性2020
- Author(s)
  郭倩倩, 徐澤宇, 斉藤広子, 砂田成章, 三木義男
- Organizer
  第79回癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H04333
[Presentation] ステロイドホルモンはトポイソメラーゼ2機能不全に伴う毒性を増強する2020
- Author(s)
  趙ニン, 砂田成章, 三木義男
- Organizer
  第79回癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H04333
[Presentation] Tioxoloneによる新たな合成致死療法の開発2020
- Author(s)
  張抖抖, 砂田成章, 三木義男
- Organizer
  第79回癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H04333
[Presentation] 遺伝子修復を標的とする新しい治療法の開発2020
- Author(s)
  三木義男, 砂田成章, 中西啓
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03497
[Presentation] Familial Cancer - Molecular Basis and its Implications for Clinical Practice -2019
- Author(s)
  Yoshio Miki
- Organizer
  the 78th Annual Meeting of the Japanese Cancer Association
- Invited
- Data Source
  KAKENHI-PROJECT-18K19473
[Presentation] ゲノム情報を基盤としたこれからの乳がん治療2019
- Author(s)
  三木義男
- Organizer
  第 27 回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19473
[Presentation] ゲノム情報を基盤としたこれからの乳がん治療2019
- Author(s)
  三木義男
- Organizer
  第 27 回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Presentation] BRCA1 and BRCA2 responsible for HBOC: molecular mechanisms and clinical impact in cancer therapy2019
- Author(s)
  Yoshio Miki
- Organizer
  Academic Session, National Institute of Genomic Medicine, Mexico
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Presentation] 細胞周期依存的なDNA修復機構を利用したがん特異的な放射線増感法の開発,2019
- Author(s)
  砂田成章, 斉藤広子, 三木義男
- Organizer
  日本放射線影響学会第61回大会
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] BRCA1 and BRCA2 responsible for HBOC: molecular mechanisms and clinical impact in cancer therapy2019
- Author(s)
  Yoshio Miki
- Organizer
  6th Annual Meeting, DEL COLEGIO MEXICANO PARA, LA INVESTIGACION DEL CANCER
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19473
[Presentation] BRCA1 and BRCA2 responsible for HBOC: molecular mechanisms and clinical impact in cancer therapy2019
- Author(s)
  Yoshio Miki
- Organizer
  6th Annual Meeting, DEL COLEGIO MEXICANO PARA, LA INVESTIGACION DEL CANCER
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03497
[Presentation] BRCA1 and BRCA2 responsible for HBOC: molecular mechanisms and clinical impact in cancer therapy2019
- Author(s)
  Yoshio Miki
- Organizer
  Academic Session, National Institute of Genomic Medicine, Mexico
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19473
[Presentation] BRCA VUSに対する機能的評価の取り組み2019
- Author(s)
  三木義男
- Organizer
  第 27 回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Presentation] 遺伝性乳がんの分子標的治療－現状と将来展望－2019
- Author(s)
  三木義男、中西啓
- Organizer
  第119回日本外科学会定期学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Presentation] 遺伝性乳がんの分子標的治療－現状と将来展望－2019
- Author(s)
  三木義男、中西啓
- Organizer
  第119回日本外科学会定期学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03497
[Presentation] Familial Cancer - Molecular Basis and its Implications for Clinical Practice -2019
- Author(s)
  Yoshio Miki
- Organizer
  the 78th Annual Meeting of the Japanese Cancer Association
- Invited
- Data Source
  KAKENHI-PROJECT-19H03497
[Presentation] BRCA1 and BRCA2 responsible for HBOC: molecular mechanisms and clinical impact in cancer therapy2019
- Author(s)
  Yoshio Miki
- Organizer
  Academic Session, National Institute of Genomic Medicine, Mexico
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03497
[Presentation] 遺伝性乳がんの分子標的治療－現状と将来展望－2019
- Author(s)
  三木義男、中西啓
- Organizer
  第119回日本外科学会定期学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19473
[Presentation] BRCA VUSに対する機能的評価の取り組み2019
- Author(s)
  三木義男
- Organizer
  第 27 回日本乳癌学会学術総会、
- Invited
- Data Source
  KAKENHI-PROJECT-19H03497
[Presentation] 細胞周期依存的なDNA修復機構を利用したがん特異的な放射線増感法の開発2019
- Author(s)
  砂田成章, 斉藤広子, 三木義男
- Organizer
  日本放射線影響学会第61回大会
- Data Source
  KAKENHI-PROJECT-18K19473
[Presentation] ゲノム情報を基盤としたこれからの乳がん治療2019
- Author(s)
  三木義男
- Organizer
  第 27 回日本乳癌学会学術総会、
- Invited
- Data Source
  KAKENHI-PROJECT-19H03497
[Presentation] Familial Cancer - Molecular Basis and its Implications for Clinical Practice -2019
- Author(s)
  Yoshio Miki
- Organizer
  the 78th Annual Meeting of the Japanese Cancer Association
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Presentation] BRCA VUSに対する機能的評価の取り組み2019
- Author(s)
  三木義男
- Organizer
  第 27 回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19473
[Presentation] BRCA1 and BRCA2 responsible for HBOC: molecular mechanisms and clinical impact in cancer therapy2019
- Author(s)
  Yoshio Miki
- Organizer
  6th Annual Meeting, DEL COLEGIO MEXICANO PARA, LA INVESTIGACION DEL CANCER
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Presentation] 乳癌の治療戦略 DNA損傷応答を標的とした新たな乳がん治療戦略2018
- Author(s)
  三木義男, 中西啓
- Organizer
  第26回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Presentation] 遺伝子パネルによる乳がん発症危険度の遺伝学的検査2018
- Author(s)
  三木義男
- Organizer
  第56回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19473
[Presentation] エストロゲンによる乳管及び基底膜崩壊機構の解析2018
- Author(s)
  Deng Yu, 中西啓, 三木義男
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] エストロゲンによる乳管及び基底膜崩壊機構の解析2018
- Author(s)
  Deng Yu, 中西啓, 三木義男
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Presentation] DNA損傷修復機構　がん抑制機能と新たながん治療への応用2018
- Author(s)
  三木義男
- Organizer
  第26回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Presentation] 遺伝子パネルによる乳がん発症危険度の遺伝学的検査　有効性，2018
- Author(s)
  三木義男
- Organizer
  第56回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] 乳癌の治療戦略 DNA損傷応答を標的とした新たな乳がん治療戦略，2018
- Author(s)
  三木義男, 中西啓
- Organizer
  第26回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19473
[Presentation] エストロゲンによる乳管及び基底膜崩壊機構の解析2018
- Author(s)
  Deng Yu, 中西啓, 三木義男
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19473
[Presentation] 遺伝子パネルによる乳がん発症危険度の遺伝学的検査2018
- Author(s)
  三木義男
- Organizer
  第56回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Presentation] DNA損傷修復機構　がん抑制機能と新たながん治療への応用2018
- Author(s)
  三木義男
- Organizer
  第26回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19473
[Presentation] DNA損傷修復機構　がん抑制機能と新たながん治療への応用2018
- Author(s)
  三木義男
- Organizer
  第26回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] 細胞周期依存的なDNA修復機構を利用したがん特異的な放射線増感法の開発2018
- Author(s)
  砂田成章, 斉藤広子, 三木義男
- Organizer
  日本放射線影響学会第61回大会
- Data Source
  KAKENHI-PUBLICLY-18H04898
[Presentation] 乳癌の治療戦略 DNA損傷応答を標的とした新たな乳がん治療戦略，2018
- Author(s)
  三木義男, 中西啓
- Organizer
  第26回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] FKBP51 のRhoAシグナル経路を通した細胞の遊走能、浸潤能の制御2017
- Author(s)
  髙岡美帆、伊藤駿、中西啓、三木義男
- Organizer
  第７６回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2017-09-28
- Data Source
  KAKENHI-PROJECT-16K08639
[Presentation] 遺伝性乳がん、卵巣がんの遺伝学的検査　―現状と展望―2017
- Author(s)
  三木義男
- Organizer
  第23回日本家族性腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01570
[Presentation] BRCA2とエストロゲン受容体相互作用による生理的役割2017
- Author(s)
  東條陽、佐藤亜美、高岡美帆、中西啓、三木義男
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] 乳癌の遺伝子発現・変異 BRCA1/2遺伝子の機能不全と乳癌2017
- Author(s)
  三木義男
- Organizer
  第25回日本乳癌学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] BRCA2とエストロゲン受容体相互作用による生理的役割2017
- Author(s)
  東條陽、佐藤亜美、高岡美帆、中西啓、三木義男
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01570
[Presentation] BRCA2ノックダウン細胞に対するパクリタキセルによる合成致死誘導機構の解明2017
- Author(s)
  山田翔太、高岡美帆、中西啓、三木義男
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01570
[Presentation] BRCA2ノックダウン細胞に対するパクリタキセルによる合成致死誘導機構の解明2017
- Author(s)
  山田翔太、高岡美帆、中西啓、三木義男
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] 遺伝性乳がん、卵巣がんの遺伝学的検査　―現状と展望―2017
- Author(s)
  三木義男
- Organizer
  第23回日本家族性腫瘍学会学術集
- Invited
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] 三次元基底膜培養のMCF-10A乳腺上皮腺房に対するエストロゲンの作用効果2017
- Author(s)
  Yu Deng、高岡美帆、中西啓、三木義男
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] 三次元基底膜培養のMCF-10A乳腺上皮腺房に対するエストロゲンの作用効果2017
- Author(s)
  Yu Deng、高岡美帆、中西啓、三木義男
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01570
[Presentation] 乳癌の遺伝子発現・変異 BRCA1/2遺伝子の機能不全と乳癌2017
- Author(s)
  三木義男
- Organizer
  第25回日本乳癌学会総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01570
[Presentation] DNA ２本鎖切断修復のシグナリング制御へのポリADP-リボシル化の関与2016
- Author(s)
  益谷美都子，Junhui Wang，佐々木由香，小野寺貴恵，藤森浩彰、三木義男，茂木章
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K14394
[Presentation] DNA ２本鎖切断修復のシグナリング制御へのポリADP-リボシル化の関与2016
- Author(s)
  益谷美都子，Junhui Wang，佐々木由香，小野寺貴恵，藤森浩彰、三木義男，茂木章
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] HBOC発症の分子機構と新規治療戦略2016
- Author(s)
  三木義男, 中西啓
- Organizer
  第24回日本乳癌学会総会
- Place of Presentation
  東京ビッグサイト（東京都江東区）
- Year and Date
  2016-06-16
- Invited
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] BRCA機能とそれらを標的とした新規がん治療法の開発2016
- Author(s)
  三木義男
- Organizer
  第37回日本臨床薬理学会学術総会
- Place of Presentation
  米子コンベンションセンター（鳥取県米子市）
- Year and Date
  2016-12-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01570
[Presentation] HBOC発症の分子機構と新規治療戦略2016
- Author(s)
  三木義男, 中西啓
- Organizer
  第24回日本乳癌学会総会
- Place of Presentation
  東京ビッグサイト（東京都江東区）
- Year and Date
  2016-06-16
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01570
[Presentation] エストラジオール誘導によるBRCA2遺伝子発現機構の解析2016
- Author(s)
  佐藤亜美，高岡美帆，中西啓，三木義男
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] DNA損傷修復機能を標的とした新規がん治療戦略2016
- Author(s)
  三木　義男
- Organizer
  第22回日本家族性腫瘍学会学術集会
- Place of Presentation
  ひめぎんホール（愛媛県松山市）
- Year and Date
  2016-06-03
- Invited
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] Development of Lasso clustering method with application to basal-like breast cancer microarray data2016
- Author(s)
  Ushijima M, Miyaguchi K, Mori S, Miki Y, Matsuura M.
- Organizer
  10th AACR-JCA joint conference
- Place of Presentation
  HYATT Regency, Maui, HW
- Year and Date
  2016-02-17
- Data Source
  KAKENHI-PROJECT-25330054
[Presentation] エストラジオール誘導によるBRCA2遺伝子発現機構の解析2016
- Author(s)
  佐藤亜美，高岡美帆，中西啓，三木義男
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14394
[Presentation] M期染色体におけるBRCA2タンパク質のインタラクトーム解析2016
- Author(s)
  大塚菜央，高岡美帆，中西啓，三木義男
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H04693
[Presentation] HBOC発症の分子機構と新規治療戦略2016
- Author(s)
  三木義男, 中西啓
- Organizer
  第24回日本乳癌学会総会
- Place of Presentation
  東京ビッグサイト（東京都江東区）
- Year and Date
  2016-06-16
- Invited
- Data Source
  KAKENHI-PROJECT-15K14394
[Presentation] H3K4 ヒストンメチル化機構におけるBRCA2の新規機能解析2016
- Author(s)
  大塚菜央，高岡美帆，中西啓，三木義男
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PUBLICLY-16H01570
[Presentation] M期染色体におけるBRCA2タンパク質のインタラクトーム解析2016
- Author(s)
  大塚菜央，高岡美帆，中西啓，三木義男；
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K14394
[Presentation] HBOCの基礎研究と家族性乳がんの新たな臨床遺伝学2015
- Author(s)
  三木義男
- Organizer
  日本人類遺伝学会第60回大会、
- Place of Presentation
  京王プラザホテル、東京都新宿区
- Year and Date
  2015-10-14
- Invited
- Data Source
  KAKENHI-PROJECT-15K14394
[Presentation] BRCA遺伝子の基礎から臨床へ2015
- Author(s)
  三木義男
- Organizer
  第27回日本内分泌外科学会総会
- Place of Presentation
  コラッセふくしま、福島県福島市
- Year and Date
  2015-05-28
- Invited
- Data Source
  KAKENHI-PROJECT-15K14394
[Presentation] BRCA2欠損細胞に対する微小管阻害剤による新規合成致死誘導機構の解明2015
- Author(s)
  三木義男
- Organizer
  第23回日本乳癌学会
- Place of Presentation
  東京国際フォーラム、東京都千代田区
- Year and Date
  2015-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K14394
[Presentation] Lasso クラスタリング法の開発とbasal-like 乳がんマイクロアレイデータへの応用2015
- Author(s)
  牛嶋大, 宮口健, 森誠一, 三木義男, 松浦正明
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-25330054
[Presentation] 次世代ゲノム解析による遺伝性乳がんの新規原因遺伝子の探索2013
- Author(s)
  三木義男
- Organizer
  日本人類遺伝学会第58回大会
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] 遺伝性乳癌患者でみられるBRCA2 遺伝子内の変異が細胞質分裂に与える影響2013
- Author(s)
  高岡美帆、斉藤広子、中西啓、三木義男
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-25134709
[Presentation] 新規BRCA機能とそれに基づく合成致死療法の開発2013
- Author(s)
  三木義男
- Organizer
  第51回日本癌治療学会学術集会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25640061
[Presentation] 遺伝性乳癌患者でみられるBRCA2 遺伝子内の変異が細胞質分裂に与える影響．2013
- Author(s)
  高岡美帆、斉藤広子、中西啓、三木義男
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25640061
[Presentation] Functional analysis of a cleavage product of BRCA2 in cancer cell lines2013
- Author(s)
  Nadila Wali, Kana Hosokawa, Hiroko Saito, Shinobu Ohmi, Akira Nakanishi, Yoshio Miki,
- Organizer
  ASCB 2013 Annual meeting
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] Functional analysis of a cleavage product of BRCA2 in cancer cell lines2013
- Author(s)
  Nadila Wali, Kana Hosokawa, Hiroko Saito, Shinobu Ohmi, Akira Nakanishi, Yoshio Miki
- Organizer
  ASCB 2013 Annual meeting
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PUBLICLY-25134709
[Presentation] Development of clustering-based gene selection method with application to breast cancer subtype data2013
- Author(s)
  牛嶋　大、三木義男、松浦正明
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25330054
[Presentation] 新規BRCA機能とそれに基づく合成致死療法の開発2013
- Author(s)
  三木義男
- Organizer
  第51回日本癌治療学会学術集会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] 遺伝性乳癌患者でみられるBRCA2 遺伝子内の変異が細胞質分裂に与える影響2013
- Author(s)
  高岡美帆、斉藤広子、中西啓、三木義男
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] Functional analysis of a cleavage product of BRCA2 in cancer cell lines2013
- Author(s)
  Nadila Wali, Kana Hosokawa, Hiroko Saito, Shinobu Ohmi, Akira Nakanishi, Yoshio Miki,
- Organizer
  ASCB 2013 Annual meeting,
- Place of Presentation
  New Orleans, LA, USA,
- Data Source
  KAKENHI-PROJECT-25640061
[Presentation] 新規BRCA機能とそれに基づく合成致死療法の開発2013
- Author(s)
  三木義男
- Organizer
  第51回日本癌治療学会学術集会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PUBLICLY-25134709
[Presentation] BRCA2の新規機能と合成致死理論に基づく新規乳癌治療法開発の可能性2012
- Author(s)
  三木　義男
- Organizer
  第20回日本乳癌学会学術総会
- Place of Presentation
  熊本市
- Year and Date
  2012-06-28
- Invited
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] Phosphorylation of BRCA2 by Akt is involved in BRCA2-14-3-3 gamma interaction related to centrosome dynamics 中心体制御に関わるBRCA2‐14-3-3γ複合体形成にはAktによるBRCA2のリン酸化が関与する2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] The correlation of decorin and periostin indicated by the proteomics of phyllodes葉状腫瘍のプロテオーム解析から導いたdecorinとperiostinの関連性2012
- Author(s)
  石場俊之,中西啓,高木洋子,笠原舞,杉本斉,永原誠,中川剛士,佐藤隆宣,杉原健一,三木義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] Hereditary breast/ovarian cancer -New development of the molecular diagnosis and treatment-遺伝性乳がん・卵巣がん症候群-分子診断・治療の新たな展開2012
- Author(s)
  三木義男,中西啓
- Organizer
  第71回日本癌学会学術総会シンポジウム
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] 乳癌新規予後予測因子Stathmin1の検討2012
- Author(s)
  三木　義男
- Organizer
  第20回日本乳癌学会学術総会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] 乳癌新規予後予測因子Stathmin1の検討2012
- Author(s)
  三木　義男
- Organizer
  第20回日本乳癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] 遺伝性乳がん卵巣がんの現状問題点と展望遺伝性乳がん原因遺伝子BRCA2の新規機能と新たな治療法開発の試み2012
- Author(s)
  三木義男
- Organizer
  第18回日本家族性腫瘍学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] Proteasome activity affects cancerous centrosome hypertrophy プロテアソームの活性は癌細胞における中心体の肥大化に影響する2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] Phosphorylation of BRCA2 by Akt is involved in BRCA2-14-3-3 gamma interaction related to centrosome dynamics2012
- Author(s)
  Miyaguchi K,Miki Y, Nakanishi A
- Organizer
  15th International Congress on Hormonal Steroids and Hormones& Cancer
- Place of Presentation
  Kanazawa
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] BRCA2 contributes success of cytokinesis through regulation of non-muscle myosin IIC ATPase activity 乳癌原因遺伝子産物 BRCA2 は II型ミオシンIIC の ATPase 活性の制御を通して細胞質分裂に働く2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] Dysregulation of c-Jun/c-Myc expression by depletion of DYRK2 triggers tumorigenesis DYRK2の発現欠失によるc-Jun/c-Mycの制御異常は細胞の腫瘍化を引き起こす2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] BRCA2 contributes success of cytokinesis through regulation of non-muscle myosin IIC ATPase activity 乳癌原因遺伝子産物 BRCA2 は II型ミオシンIIC の ATPase 活性の制御を通して細胞質分裂に働く2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] Phosphorylation of BRCA2 by Akt is involved in BRCA2-14-3-3 gamma interaction related to centrosome dynamics 中心体制御に関わるBRCA2‐14-3-3γ複合体形成にはAktによるBRCA2のリン酸化が関与する2012
- Author(s)
  宮口健,郭甜甜,三木義男,中西啓
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] Dysregulation of c-Jun/c-Myc expression by depletion of DYRK2 triggers tumorigenesis DYRK2の発現欠失によるc-Jun/c-Mycの制御異常は細胞の腫瘍化を引き起こす2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] Proteasome activity affects cancerous centrosome hypertrophy プロテアソームの活性は癌細胞における中心体の肥大化に影響する2012
- Author(s)
  木村仁美,中西啓,三木義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] BRCA2の新規機能と合成致死理論に基づく新規乳癌治療法開発の可能性2012
- Author(s)
  三木義男
- Organizer
  第20回日本乳癌学会学術総会
- Place of Presentation
  熊本市(招待講演)
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] 切断型BRCA2の形成機序および機能解析2012
- Author(s)
  三木　義男
- Organizer
  日本人類遺伝学会第57回大会
- Place of Presentation
  東京
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] BRCA2 contributes success of cytokinesis through regulation ofnon-muscle myosin IIC ATPase activity乳癌原因遺伝子産物BRCA2はII型ミオシンIICのATPase活性の制御を通して細胞質分裂に働く2012
- Author(s)
  高岡美帆,斉藤広子,中西啓,三木義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] 遺伝性乳がん・卵巣がん症候群の分子診断2012
- Author(s)
  三木義男
- Organizer
  田辺市・西牟婁郡・日高三医師会学術講演会
- Place of Presentation
  和歌山県田辺市(招待講演)
- Year and Date
  2012-03-03
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] The correlation of decorin and periostin indicated by the proteomics of phyllodes 葉状腫瘍のプロテオーム解析から導いたdecorinとperiostinの関連性2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] Analysis of a centrosome localization signal （CLS） in BRCA2 BRCA2由来中心体局在化シグナル（CLS）の機能解析2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] 遺伝性乳がん卵巣がんの現状　問題点と展望遺伝性乳がん原因遺伝子BRCA2の新規機能と新たな治療法開発の試み．2012
- Author(s)
  三木　義男
- Organizer
  第18回日本家族性腫瘍学会学術集会
- Place of Presentation
  大阪市
- Invited
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] The correlation of decorin and periostin indicated by the proteomics of phyllodes 葉状腫瘍のプロテオーム解析から導いたdecorinとperiostinの関連性2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] Analysis of a centrosome localization signal （CLS） in BRCA2 BRCA2由来中心体局在化シグナル（CLS）の機能解析2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] Hereditary breast/ovarian cancer -New development of the molecular diagnosis and treatment-遺伝性乳がん・卵巣がん症候群-分子診断・治療の新たな展開-2012
- Author(s)
  三木義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] Hereditary breast/ovarian cancer -New development of the molecular diagnosis and treatment- 遺伝性乳がん・卵巣がん症候群-分子診断・治療の新たな展開-2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Invited
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] 遺伝性乳がん卵巣がんの現状　問題点と展望遺伝性乳がん原因遺伝子BRCA2の新規機能と新たな治療法開発の試み2012
- Author(s)
  三木　義男
- Organizer
  第18回日本家族性腫瘍学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2012-06-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] BRCA2の新規機能と合成致死理論に基づく新規乳癌治療法開発の可能性2012
- Author(s)
  三木義男,中西啓
- Organizer
  第20回日本乳癌学会学術総会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] Hereditary breast/ovarian cancer -New development of the molecular diagnosis and treatment-遺伝性乳がん・卵巣がん症候群-分子診断・治療の新たな展開-2012
- Author(s)
  三木義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市(招待講演)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] Hereditary breast/ovarian cancer -New development of the molecular diagnosis and treatment- 遺伝性乳がん・卵巣がん症候群-分子診断・治療の新たな展開-2012
- Author(s)
  三木　義男
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Invited
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] 網羅的遺伝子発現情報のがん個別化治療への展開2011
- Author(s)
  三木義男
- Organizer
  第35回日本頭頸部癌学会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] New insights into the cellular function of BRCA22011
- Author(s)
  Miki Y, Takenaka K, Nakanishi A
- Organizer
  70^<th> Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] 遺伝性乳がん卵巣がんの臨床BRCA1/2遺伝子検査と薬物療法BRCA1/2研究の現状と展望基礎から臨床2011
- Author(s)
  三木義男
- Organizer
  第17回日本家族性腫瘍学会学術集会、シンポジウム
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] BRCA1/2遺伝子の分子生物学－遺伝子の発見から今、そして今後の展望－2011
- Author(s)
  三木義男
- Organizer
  第14回家族性腫瘍セミナー(招待講演)
- Place of Presentation
  東大阪市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] New insights into the cellular function of BRCA2.2011
- Author(s)
  Miki Y, Takenaka K, Nakanishi A.
- Organizer
  70th Annual Meeting of the Japanese Cancer Association(招待講演)
- Place of Presentation
  Nagoya, Japan,
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] BRCA1/2遺伝子検査の先進医療への取組み2011
- Author(s)
  三木義男
- Organizer
  第19回日本乳癌学会学術総会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] 遺伝性乳がん・卵巣がん症候群の分子遺伝2011
- Author(s)
  三木義男
- Organizer
  第47回北九州乳腺カンファレンス(招待講演)
- Place of Presentation
  北九州市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] 遺伝性乳癌・卵巣癌症候群－基礎から臨床－2011
- Author(s)
  三木義男、斉藤広子、中西啓
- Organizer
  日本人類遺伝学会第56回大会・第11回東アジア人類遺伝学会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] 遺伝性乳がん・卵巣がん症候群の分子遺伝2011
- Author(s)
  三木義男
- Organizer
  第47回北九州乳腺カンファレンス、特別講演
- Place of Presentation
  北九州市
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] BRCA1/2遺伝子の分子生物学-遺伝子の発見から今、そして今後の展望-2011
- Author(s)
  三木義男
- Organizer
  第14回家族性腫瘍セミナー
- Place of Presentation
  東大阪市
- Data Source
  KAKENHI-PUBLICLY-23134503
[Presentation] BRCA1/2研究の現状と展望2011
- Author(s)
  三木義男
- Organizer
  第17回日本家族性腫瘍学会学術集会(招待講演)
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] Aurora Kinase B is a novel target for treatment of hepatocellular carcinoma2010
- Author(s)
  Tanaka S, Aihara A, Mahmut Y, Mogushi K, Taira K, Kudo A, Nakamura N, Ito K, Imoto I, EishiY, Miki Y, Inazawa J, Tanaka H, Arii S
- Organizer
  AACR Annual Meeting 2008. 2010. 4. 19. Washington, DC, America
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-20249061
[Presentation] ライブラリー型RNA干渉を用いたアポトーシス誘導関連遺伝子の網羅的探索(The functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in human cancer cells).2009
- Author(s)
  木村純子;平直江;三木義男;吉田清嗣
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 乳癌の新規予後因子の同定.2009
- Author(s)
  吉村慶子;長埼光一;岩瀬拓士;秋山太;三木義男
- Organizer
  第17回日本乳癌学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 遺伝カウンセリング後のhnpcc患者・家族の近親者への医療機関受診勧奨支援の重要性について.2009
- Author(s)
  石井紀子;新井正美;三木義男
- Organizer
  第17回日本乳癌学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] Pim-1はRelA/p65のSer276をリン酸化することでNF-κBの活性化を制御する(Pim-1 kinase controls the transcription activity of NF-kappaB through phosphorylation of the RelA/p65 subunit at Ser276).2009
- Author(s)
  仁平啓史;三木義男;吉田清嗣
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 分子情報を用いた個別化医療のTR乳がんの抗がん剤治療効果予測法の開発(Translational research for personalized medicine based on genome information of cancer patients Genomic study for response prediction of breast cancer chemotherapy)(シンポジウム).2009
- Author(s)
  三木義男;長崎光一;牛嶋大;宮田敏;松浦正明;野田哲生
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 分子生物学的手法による高分化型脂肪肉腫の鑑別診断の試み.2009
- Author(s)
  五木田茶舞;阿江啓介;下地尚;石田剛;松本誠一;三木義男;四宮謙一
- Organizer
  第82回日本整形外科学会学術総
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] Aurora Kinase B pathway as a novel molecular target in invasive hepatocellular carcinoma2009
- Author(s)
  Tanaka S, Mogushi K, Aihara A, YasenM, Noguchi N, Kudo A, Kurokawa T, Nakamura N, Miki Y, Inazawa J, TanakaH, Arii S
- Organizer
  AACR Annual Meeting 2009
- Place of Presentation
  Denver, CO, USA
- Year and Date
  2009-04-20
- Data Source
  KAKENHI-PROJECT-20249061
[Presentation] Brca2は14-3-3γと結合して中心体の凝集に関与する.2009
- Author(s)
  三木義男;中西啓
- Organizer
  第15回日本家族性腫瘍学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] BRCA2- Myosin IIC complex is localized to the midbody of cytokinesis and required the completion of cytokinesis2009
- Author(s)
  中西啓;斉藤広子;大海忍;福田宏之;高村千鶴子;三木義男
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 細胞周期に関連する網羅的リン酸化タンパクの定量解析(Comprehensive phosphoproteome analysis during the cell cycle of Hela S3 cells).2009
- Author(s)
  斉藤広子;中西啓;三木義男
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 乳がんにおけるstmn1高発現症例の病理学的特徴.2009
- Author(s)
  大石陽子;三浦妙太;佐原八束;川村徹;佐藤康;中嶋昭;三木義男
- Organizer
  第17回日本乳癌学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] Molecular prediction of therapeutic response and adverse effect of chemotherapy in breast cancer2009
- Author(s)
  Miki Y.
- Organizer
  Institute for Genetic Medicine, Hokkaido University, Research Center for Infection-associated Cancer(RCIAC), International Symposium New Frontiers in Cancer Research
- Place of Presentation
  Hokkaido Japan
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] ATMによるDYRK2のリン酸化はMDM2を介したユビキチン化の阻害に必要である(ATM phosphorylation of DYRK2 confers resistance to ubiquitination-mediated degradation by MDM2).2009
- Author(s)
  平直江;三木義男;吉田清嗣
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 乳癌における新規遺伝子多型の同定.2009
- Author(s)
  小松哲;長崎光一;篠原剛;五十嵐淳;藤森芳郎;山岸喜代文;西村博行;藤森実;三木義男
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] トランスフェクションアレイを用いた薬剤感受性遺伝子の機能ネットワーク解析(Functional Screening for Chemo-sensitivity Related Genes by Transfection Cell Array).2009
- Author(s)
  長崎光一;下地尚;星川裕;松浦正明;野田哲生;三木義男
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 乳がん治療の個別化病態に応じた治療法の最近の進歩遺伝子診断による個別化乳癌術前化学療法(Personalized breast cancer therapy: recent adwanees in breast cancer therapy tailored to individual clinical conditions Individualized primary chemotherapy by genetic diagnosis for breast cancer).2009
- Author(s)
  伊藤良則;三木義男;秋山太;松浦正明;長崎光一;岩瀬拓士;畠清彦
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 乳癌における治療効果予測因子の現状と今後の展望化学療法の効果予測因子基礎の立場から(シンポジウム).2009
- Author(s)
  三木義男;牛嶋大;松浦正明;長崎光一
- Organizer
  第17回日本乳癌学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 肝癌再発ネットワーク解析に基づくAurora kinase B分子標的治療の開発(Aurora kinase B addiction as a novel molecular target in hepatocellular carcinoma with aggressive recurrence).2009
- Author(s)
  田中真二;藍原有弘;茂櫛薫;ヤーセン・マームット;野口典男;入江工;工藤篤;中村典明;井本逸勢;三木義男, others.
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 乳がんと膵がんに関連するヒトがん幹細胞の分子学的特性解析(Molecular characterization of human cancer stem cells-associated breast and pancreatic carcinoma).2009
- Author(s)
  塩谷尚志;河口徳一;菅原稔;長崎光一;磯村実;牛嶋大;松浦正明;三木義男;野田哲生
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] パクリタキセルの末梢神経障害を予測する遺伝的マーカーの探索(Genome wide association study to identify genetic marker for prediction of peripheral neuropathy of paclitaxel treatment).2009
- Author(s)
  磯村実;松浦正明;野田哲生;三木義男
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] Aurora Kinase B pathway as a novel molecular target in invasive hepatocellular carcinoma.2009
- Author(s)
  Tanaka S, Mogushi K, Aihara A, Yasen M, Noguchi N, Kudo A, Kurokawa T, Nakamura N, Miki Y, Inazawa J, Tanaka H, Arii S.
- Organizer
  AACR Annual Meeting 2009.
- Place of Presentation
  Denver, CO, USA
- Year and Date
  2009-04-20
- Data Source
  KAKENHI-PROJECT-20249061
[Presentation] 乳癌の化学療法感受性予測の試み2008
- Author(s)
  三木義男, 他
- Organizer
  第16回日本乳癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2008-09-26
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 乳がん術前化学療法の効呆予測システム開発の試み2008
- Author(s)
  三木義男
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] 乳癌診療標準化から個別化へ乳癌の化学療法感受性予測の試み2008
- Author(s)
  三木義男, 長崎光一, 牛嶋大, 松浦正明
- Organizer
  第16回日本乳癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] 乳がん術前化学療法の効果予測システム開発の試み2008
- Author(s)
  三木義男
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] Pim-1はRelA/p65のリン酸化を介してNF-kBの活性化を制御する2008
- Author(s)
  仁平啓史、安藤雄祐、山口智子、三木義男、吉田清嗣
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] 乳癌の化学療法感受性予測の試み.2008
- Author(s)
  三木義男, 他
- Organizer
  第16回日本乳癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] Aurora Kinase B is a novel target for treatment of hepatocellular carcinoma.2008
- Author(s)
  Tanaka S, Aihara A, Mahmut Y, Mogushi K, Taira K , Kudo A, Nakamura N, Ito K, Imoto I, Eishi Y, Miki Y, Inazawa J, Tanaka H, Arii S.
- Organizer
  AACR Annual Meeting 2008
- Place of Presentation
  San Diego, USA
- Year and Date
  2008-04-15
- Data Source
  KAKENHI-PROJECT-20249061
[Presentation] 乳がん基礎・病理・1次予防BRCA2-Plectin複合体は中心体の固定に関与する2008
- Author(s)
  三木義男, 丹羽隆善, 斉藤弘子, 中西啓
- Organizer
  第14回日本家族性腫瘍学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] アポトーシス誘導関連遺伝子の網羅的探索によるTAF1の同定と機能解析2008
- Author(s)
  木村純子、グェンティエンスー、平直江、三木義男、吉田清嗣
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] ATMはDYRK2のリン酸化はキナーゼ活性を制御するとともに、MDM2を介したプロテアソーム系による分解からの回避を引き起こす2008
- Author(s)
  平直江、山本宙亨、山口智子、三木義男、吉田清嗣
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] 遺伝性の癌その研究と臨床の最前線遺伝性乳癌卵巣癌が疑われる日本人を対象とするBRCA1/2遺伝子変異の横断的研究(Forefront of Basic and Clinical Researches in Hereditary Cancer Cross-sectional study of BRCA1 and BRCA2 mutations in Japanese patients suspected of hereditary breast/ovarian carcinoma)2008
- Author(s)
  菅野康吉, 中村清吾, 安藤二郎, 神野浩光, 池田正, 青木大輔, 福富隆志, 吉田輝彦, 新井正美, 平井康夫, 霞富士雄, 福井崇史, 三木義男
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] 乳がん術前化学療法の効果予測システム開発の試み(Molecular prediction of the therapeutic response to neoadjuvant chemotherapy in breast cancer)2008
- Author(s)
  三木義男
- Organizer
  第108回日本外科学会定期学術集会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] BRCA2-Plectin複合体は中心体の固定に関与する2008
- Author(s)
  三木義男, 他
- Organizer
  第14回日本家族性腫瘍学会学術集会
- Place of Presentation
  東京
- Year and Date
  2008-06-20
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 肝細胞癌再発様式のオミックス解析による新規分子標的の同定2007
- Author(s)
  田中真二, Yasen Mahmut, 茂櫛薫, 藍原有弘, 工藤篤, 中村典明, 伊東浩次, 井本逸勢, 稲澤譲治, 三木義男, 水島洋, 田中博, 有井滋樹.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  神奈川
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18209043
[Presentation] 酸化ストレス下における、BRCA1およびpRbを介したubiquitinationによるtopoisomerase II alphaの活性阻害(BRCA1-mediated ubiquitination through pRb inhibits topoisomerase II alpha activity in response to oxidative stress)(英語)2007
- Author(s)
  品川弘州, 三木義男, 吉田清嗣
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] BRCA2と相互作用する新規蛋白質プレクチン(Plectin, a novel protein which interacts with BRCA2)(英語)2007
- Author(s)
  丹羽隆善, 中西啓, 大海忍, 上西紀夫, 三木義男
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] 網羅的疾患分子病態データベースの構築2007
- Author(s)
  田中博, 有井滋樹, 杉原健一, 三木義男, 稲澤譲治, 水島洋.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  神奈川
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18209043
[Presentation] ゲノム、トランスクリプトーム情報の癌個別化治療への展開2007
- Author(s)
  三木義男
- Organizer
  第44回日本臨床分子医学会学術集会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] DNA損傷に対するアポトーシス反応においてDYRK2は核を標的とし、Ser46リン酸化を介してp53を制御する(DYRK2 is Targeted to the Nucleus and Controlsp53 via Ser46 Phosphorylation in the ApoptoticResponse to DNA Damage)(英語)2007
- Author(s)
  平直江, 三木義男, 吉田清嗣
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] BRCA2における機能的核輸送配列の同定(Identification of a Functional Nuclear Export Sequence in BRCA2)(英語)2007
- Author(s)
  韓香子, 中西啓, 斉藤広子, 三木義男
- Organizer
  第66回日本癌学会学術総
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] Establishment of a Personalized Chemotherapy for Breast Cancer.2007
- Author(s)
  Miki Y, et. al.
- Organizer
  Seventh AACR/JCA Joint International Conference
- Place of Presentation
  Hawaii, USA
- Year and Date
  2007-01-25
- Data Source
  KAKENHI-PROJECT-17013027
[Presentation] 乳がんの分子遺伝学BRCAの機能と乳がん発生における役割(In the Forefront of Breast Cancer Research-Towards Steady Decrease of Cancer Mortality Breast cancer molecular biology and genetics : the role and function of BRCA1 and 2)(英語)2007
- Author(s)
  三木義男
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] 非筋肉型ミオシンIICによる細胞質分裂の制御(Nonmuscle myosin IIC regulates the division of intercellular bridge of cytokinesis)(英語)2007
- Author(s)
  中西啓, 斉藤広子, 太田吉泰, 大海忍, 三木義男
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390083
[Presentation] 肝細胞癌の分子標的治療2007
- Author(s)
  田中真二, 藍原有弘, Mahmut Yasen, 茂櫛薫, 工藤篤, 中村典明, 伊東浩次, 稲澤譲治, 三木義男, 田中博, 有井滋樹.
- Organizer
  第45回日本癌治療学会総会.
- Place of Presentation
  京都
- Year and Date
  2007-10-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18209043
[Presentation] 肝細胞癌の進展機構解析による新規分子標的の同定2007
- Author(s)
  田中真二, Yasen Mahmut, 茂櫛薫, 工藤篤, 中村典明, 伊東浩次, 稲澤譲治, 三木義男, 田中博, 有井滋樹.
- Organizer
  第62回日本消化器外科学会定期学術総会
- Place of Presentation
  東京
- Year and Date
  2007-07-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18209043
[Presentation] M期中心体におけるMT1-MMPのBRCA2タンパク分解
- Author(s)
  １０．高岡美帆、ナディラワリ、斎藤広子、中西啓、三木義男
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25640061
[Presentation] BRCA2欠失乳細胞に合成致死を誘導する有効な低分子化合物の同定
- Author(s)
  清水優香、湯浅磨里、中西啓、三木義男
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] 切断型BRCA2の形成機序および機能解析
- Author(s)
  中西啓,Nadila Wali,斉藤広子,大(1)研究代表者海,三木義男
- Organizer
  日本人類遺伝学会第57回大会
- Place of Presentation
  新宿区
- Data Source
  KAKENHI-PROJECT-23650592
[Presentation] Lasso clustering method for classification of cancer subtypes using microarray data
- Author(s)
  Masaru Ushijima, Shinto Eguchi, Osamu Komori, Yoshio Miki, Masaaki Matsuura
- Organizer
  27th International Biometric Conference
- Place of Presentation
  Florence, Italy
- Year and Date
  2014-07-07 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-25330054
[Presentation] 乳がん患者のパクリタキセル応答性に関わる遺伝子ネットワーク解析
- Author(s)
  １３．宮口健、井元清哉、牛嶋大、松浦正明、玉田嘉紀、山口類、宮野悟、三木義男
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PUBLICLY-25134709
[Presentation] BRCA2の新規機能解明に基づく診断・治療法の開発
- Author(s)
  中西啓、三木義男
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] M期中心体におけるMT1-MMPのBRCA2タンパク分解
- Author(s)
  高岡美帆、ナディラワリ、斎藤広子、中西啓、三木義男
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24300328
[Presentation] 乳がんにおける遺伝子の多様性
- Author(s)
  三木義男
- Organizer
  第14回よこはま乳がんシンポジウム
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24300328
[]

1. NAKANISHI Akira (50321790)

# of Collaborated Projects: 7 results

# of Collaborated Products: 37 results
2. Sunada Shigeaki (70807677)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. YANAGISAWA Akio (30137963)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. INAZAWA Jyouji (30193551)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
5. KATO You (20010473)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ARII Shigeki (50151171)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
7. TANAKA Shinji (30253420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
8. MATSUURA Masaaki (40173794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
9. USHIJIMA Masaru (60328565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
10. 高岡美帆 (90770701)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
11. TSUDA Hiroshi (00423880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TAKENAKA Katsuya (20378706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. ARAI Masami (20232027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. UTSUNOMIYA Jyoji (70013901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MUTO Tetsuichiro (20110695)

# of Collaborated Projects: 1 results

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16. TAKAMI Hiroshi (10146714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. IKEDA Yoshihumi (20222870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KODAIRA Susummu (00110015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KAMEYAMA Kaori (10245467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KOKUDO Norihiro (00205361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MIKI Kenji (10242059)

# of Collaborated Projects: 1 results

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22. HOSHIKAWA Yutaka (80280626)

# of Collaborated Projects: 1 results

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23. MIYATA Satoshi (60360343)

# of Collaborated Projects: 1 results

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24. EGUCHI Shinto (10168776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KONISHI Fumio (20142242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
26. KAI Toshihiro (40260830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. TANAKA Hiroshi (60155158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
28. NAKAMURA Noriaki (10372442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
29. HAMANO Yuki (90396680)

# of Collaborated Projects: 1 results

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30. DAN Shingo (70332202)

# of Collaborated Projects: 1 results

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31. 丸山雅一 (60085579)

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32. 相羽恵介 (90150086)

# of Collaborated Projects: 1 results

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33. 中島聰總 (10085590)

# of Collaborated Projects: 1 results

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34. 寺本研一 (80197813)

# of Collaborated Projects: 1 results

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35. 下川卓志 (20608137)

# of Collaborated Projects: 1 results

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36. FUKUTOMI Takeshi

# of Collaborated Projects: 1 results

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37. 菅重尚

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. ITO Hidemi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. LOW SIEWKEE

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 堤修一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 坂本啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 山口朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 吉田清嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIKI Yoshio 三木 義男

三木 義男 ミキ ヨシオ

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Development of a Novel Synthetic Lethal Therapy for Breast Cancer by Targeting DNA Homologous Recombination Repair.Principal Investigator

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Study on novel mechanism of breast cancer development by modulation of mitochondrial controlPrincipal Investigator

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MLL-Menin-BRCA2複合体によるがん抑制機能ネットワークの解析Principal Investigator

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システム的統合理解に基づく乳がん術前化学療法の応答性予測Principal Investigator

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Study on new treatment of breast cancer targeting BRCA gene functionPrincipal Investigator

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Role of BRCA2 in the process of estrogen-dependent cell proliferationPrincipal Investigator

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乳がん分子サブタイプの細胞機能特性の描出と個別化治療への展開Principal Investigator

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Elucidation of the new mechanism for breast carcinogenesis associated with early endosome.Principal Investigator

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Functional analysis of BRCA genes and searching for molecular partner for synthetic lethality.Principal Investigator

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乳癌の分子サブタイプ分類と個別化抗癌剤治療の開発Principal Investigator

Principal Investigator

MIKI Yoshio 三木義男

三木義男ミキヨシオ