AMANO Taku 天野託

Researcher Number	10294547
Other IDs
Affiliation (based on the past Project Information) *help	2010 – 2017: 国際医療福祉大学, 薬学部, 教授 2003 – 2005: Hiroshima University, Graduate School of Biomedical Sciences, Assistant Professor, 大学院・医歯薬学総合研究科, 講師 1999 – 2003: 広島大学, 医学部, 助手 2002: 広島大学, 大学院・医歯薬学総合研究科, 助手
Review Section/Research Field	Principal Investigator Pain science / 疼痛学 / General pharmacology Except Principal Investigator Biological Sciences / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Biological pharmacy / General pharmacology / Community health nursing / Cerebral neurosurgery
Keywords	Principal Investigator 電気生理学 / ナトリウムチャネル / パッチクランプ / ブシ末 / 漢方 / 痛み / 附子末 / 電気生理 / 疼痛 / 六味丸 … More / 牛車腎気丸 / 神経科学 / ナトリウムチャネルサブタイプ / 微小興奮性シナプス後電流 / 視床スライス / HEK293細胞 / 慢性疼痛 / オキシコドン / フェンタニール / モルヒネ / Na+チャネル / 腹側被蓋野 / 精神分裂病様症状 / 感受性 / 逆耐性 / 薬物依存 / メタアンフェタミン / ドーパミン … More Except Principal Investigator トランスジェニックマウス / プロテインキナーゼC / リン酸化 / transgenic mice / 神経興奮伝播 / PDK-1 / adenosine / SER / ライブイメージング / 小脳プルキンエ細胞 / 神経可塑性 / 蛋白質リン酸化 / Propagation on neuronal excitation / Purkinje cell / protein kinase C / protein phosphorylation / プルキンエ細胞 / propagation of neural excitability / protein kinase C (PKC) / phosphorylation / primary culture / neuroprotection / ischemia / gerbil / dementia / necrosis / glutamte / culture / cortex / A1 receptor / ATP / AMP / 神経保護作用 / アデノシン / グルタミン酸 / 初代培養細胞 / スナネズミ / 虚血生神経細胞死 / GABA_A receptor / Ca^<2+> channel / metabotropic glutamate receptor / N-acetyl aspartate / aspartoacetylase gene / epileptic seizure / tremor rat / ASP遺伝子 / パッチクランプ / 海馬CA3ニューロン / アスパルトアセチレース / パッチクランプ法 / N-アセチルアスパルテート / GABA_A受容体 / Ca^<2+>チャネル / 代謝型グルタミン酸受容体 / N-アセチルアスパルテート(NAA) / アスパルトアセチレース遺伝子 / てんかん発作 / トレモアラット / メンタルヘルスリテラシー / 生活習慣 / 精神的健康 / 一次予防 / 養護教諭 / 関連要因 / プログラム / レジリエンス / リテラシー / メンタルヘルス / 中学生 / biotin-avidin system / biotin-avidin / avidin-biotin system / TRAIL / 血管内皮前駆細胞 / 悪性グリオーマ / 神経変性疾患 / 凝集体 / Tet制御システム / プイロテインキナーゼC Less

Elucidation of pain control mechanism via sodium channel of novel target molecule contained in herbal medicine GoshajinkiganPrincipal Investigator
- Principal Investigator
  
  AMANO TAKU
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  International University of Health and Welfare
Research for Support of Adolescence mental health of junior high school students
- Principal Investigator
  
  FUJITA KYOKO
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Community health nursing
- Research Institution
  International University of Health and Welfare
Novel theraputic approach for maligannt glioma using endothelial progenitor cell.
- Principal Investigator
  
  HIROMICHI NAKABAYASHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Oita University of Nursing and Health Sciences
  International University of Health and Welfare
The function of Na^+channel as a novel target molecule for chronic pain treatment in thalamus neuronPrincipal Investigator
- Principal Investigator
  
  AMANO Taku
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  疼痛学
- Research Institution
  International University of Health and Welfare
変異PKCによる神経変性疾患の病因解明 -ターゲティングを指標にした解析-
- Principal Investigator
  
  酒井規雄
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
Functional analysis of protein kinase C(PKC), a molecule involved in plasticity, development and cell death in central nervous system, using gene-manipulated mice.
- Principal Investigator
  
  SAKAI Norio
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  HIROSHIMA UNIVERSITY
Mechanisms of development of ischemic neuronal cell death and protection against ischemic neuronal cell death.
- Principal Investigator
  
  TAMURA Yutaka
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Fukuyama University
Roles of protein kinase C (PKC) in the formation of neural plasticity. -Investigation using GFP-tagged PKC
- Principal Investigator
  
  SAKAI Norio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  HIROSHIMA UNIVERSITY
神経可塑性制御に対するPKCの役割-トランスジェニックマウスを用いた研究-
- Principal Investigator
  
  SAKAI Norio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
  Kobe University
Pharmacological research on Ca^<2+> channel abnormality which induces epileptic seizures
- Principal Investigator
  
  SASA Masashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  HIROSHIMA UNIVERSITY
メタアンフェタミン反復投与によるドーパミンニューロンの機能変化に関する研究Principal Investigator
- Principal Investigator
  
  天野託
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General pharmacology
- Research Institution
  Hiroshima University

All 2017 2016 2015 2014 2013 2012 2011 2010 2004 Other

All Journal Article Presentation

[Journal Article] Yokukansan enhances the proliferation of B65 neuroblastoma.2017
- Author(s)
  Nakatani Y, Amano T, Yamamoto H, Sakai N, Tsuji M, Takeda H.
- Journal Title
  
  J Tradit Complement Med.
  
  Volume: 815 Pages: 381-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460703
[Journal Article] Yokukansan enhances the proliferation of B65 neuroblastoma.2016
- Author(s)
  Nakatani Y, Amano T, Yamamoto H, Sakai N, Tsuji M, Takeda H.
- Journal Title
  
  J Tradit Complement Med.
  
  Volume: 7 Pages: 34-44
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460703
[Journal Article] Corticosterone Inhibits the Proliferation of C6 Glioma Cells via the Translocation of Unphosphorylated Glucocorticoid Receptor2016
- Author(s)
  Nakatani Y, Amano T, Takeda H.
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 39 Pages: 1121-1129
- NAID
  130005160769
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460703
[Journal Article] Yokukansan enhances the proliferation of B65 neuroblastoma2016
- Author(s)
  Yoshihiko Nakatani, Taku Amano, Hikaru Yamamoto, Norio Sakai, Minoru Tsuji, Hiroshi Takeda
- Journal Title
  
  Journal of Traditional and Complementary Medicine
  
  Volume: X Pages: 1-11
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460703
[Journal Article] Neuroprotective effect of yokukansan against cytotoxicity induced by corticosterone on mouse hippocampal neurons.2014
- Author(s)
  Nakatani Y, Tsuji M, Amano T, Miyagawa K, Miyagishi H, Saito A, Imai T, Takeda K, Ishii D and Takeda H.
- Journal Title
  
  Phytomedicine
  
  Volume: 21 Issue: 11 Pages: 1458-1465
- DOI
  10.1016/j.phymed.2014.06.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460703
[Journal Article] Corticosterone Suppresses the Proliferation of RAW264. 7 Macrophage Cells via Glucocorticoid, but not Mineralocorticoid, Receptor.2013
- Author(s)
  Y NAKATANI, T AMANO, H TAKEDA
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: 36(4) Pages: 592-601
- Data Source
  KAKENHI-PROJECT-22600014
[Journal Article] Corticosterone Suppresses the Proliferation of RAW264.7 Macrophage Cells via Glucocorticoid, But Not Mineralocorticoid, Receptor.2013
- Author(s)
  Nakatani Y, Amano T, Takeda H.
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: vol.36 Pages: 592-601
- NAID
  130003361400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600014
[Journal Article] Corticosterone suppresses the proliferation of BV2 microglia cells via glucocorticoid, but not mineralocorticoid receptor.2013
- Author(s)
  Nakatani Y, Amano T, Tsuji M, Takeda H.
- Journal Title
  
  life sciences
  
  Volume: vol.91 Issue: 15-16 Pages: 761-770
- DOI
  10.1016/j.lfs.2012.08.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600014
[Journal Article] Corticosterone Suppresses the Proliferation of BV2 Microglia Cells via Glucocorticoid, but not Mineralocorticoid Receptor.2012
- Author(s)
  Y NAKATANI, T AMANO, M TSUJI, H TAKEDA
- Journal Title
  
  Life Sciences
  
  Volume: 91 Pages: 761-770
- Data Source
  KAKENHI-PROJECT-22600014
[Journal Article] The lipid metabolism abnormality in patients administered with olanzapine.2012
- Author(s)
  T AMANO , S HOSAKA, H TAKAMI, K ODA, R MORIKAWA
- Journal Title
  
  Nihon Shinkei Seishin Yakurigaku Zasshi
  
  Volume: 32(5-6) Pages: 257-61
- NAID
  10031133447
- Data Source
  KAKENHI-PROJECT-22600014
[Journal Article] Antiepileptic effects of single and repeated oral administrations of S-312-d, a novel calcium channel antagonist, on tonic convulsions in spontaneously epileptic rats (SER).2004
- Author(s)
  Amano, T.
- Journal Title
  
  J. Pharmacol. Sci. 95
  
  Pages: 355-362
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500243
[Journal Article] Antiepileptic effects of single and repeated oral administrations of S-312-d, a novel calcium channel antagonist, on tonic convulsions in spontaneously epileptic rats (SER).2004
- Author(s)
  Amano, T.
- Journal Title
  
  J.Pharmacol.Sci. 95
  
  Pages: 355-362
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500243
[Journal Article] Acute effects of caffeine on blood pressure and heart rate in habitual and habitual coffee consumers: a randomized, double-blind, placebo-controlled study.
- Author(s)
  H OHIDE, K MIYAGAWA, T TAKEUCHI, Y NAKATANI, H YOKOYAMA, T AMANO, A HARA
- Journal Title
  
  The Journal of Applied Therapeutic Research
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] リン酸化Akt およびMAPK発現変化を介した新規ベンズインドール誘導体の抗グリオーマ作用の解明2017
- Author(s)
  藤野　恵理、八木澤　昂大、渡邊　有加里、高橋　詩織、Nyo Mi SWE、中谷　善彦、渡邊　敏子、天野　託
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-26460703
[Presentation] 牡丹皮を介した六味丸のNav1.7チャネル電流抑制作用2016
- Author(s)
  塚田和代、片所真紀、山内美輝、根来加菜子、山口真里奈、塩川真穂、遠藤沙希子、中谷善彦、矢作忠弘、松﨑桂一、天野託
- Organizer
  第134回日本薬理学会関東部会
- Place of Presentation
  栃木県
- Data Source
  KAKENHI-PROJECT-26460703
[Presentation] 抗悪性腫瘍薬の開発を指向した新規ベンズインドール誘導体の抗グリオーマ作用の検討2015
- Author(s)
  渡邊有加里、高橋詩織、Nyo Mi Swe、中谷善彦、渡邊敏子、天野託
- Organizer
  生体機能と創薬シンポジウム2015
- Place of Presentation
  日本大学薬学部
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-26460703
[Presentation] 甘草含有成分であるliquritinのセロトニン神経由来細胞株B65におけるmenadione誘導酸化ストレスに対する細胞保護効果とそのメカニズムに関する検討2015
- Author(s)
  中谷善彦、天野託、矢作忠弘、辻稔、武田弘志
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-26460703
[Presentation] Neuro2a細胞におけるSNAP25の細胞生存に及ぼす影響2015
- Author(s)
  山本彩佳、大井ありさ、根本佳奈、高木正史、高橋詩織、中谷善彦、天野託
- Organizer
  生体機能と創薬シンポジウム2015
- Place of Presentation
  日本大学薬学部
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-26460703
[Presentation] 牛車腎気丸および六味丸は電位依存性ナトリウムチャネルNav1.7電流を抑制する2014
- Author(s)
  天野　託、中谷善彦、武田弘志
- Organizer
  第131回日本薬理学会関東部会
- Place of Presentation
  横浜市大　福良キャンパス
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-26460703
[Presentation] 国際医療福祉大学薬学部における血圧測定の応用実習(第5 報)-カフェインの急性昇圧作用における性差の解析-2013
- Author(s)
  大出浩子、宮川和也、中谷善彦、宮岸寛子、池田俊也、天野託、原明義
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] 国際医療福祉大学薬学部における血圧測定の応用実習（第5報）-カフェインの急性昇圧作用における性差の解析-2013
- Author(s)
  大出浩子、宮川和也、中谷善彦、宮岸寛子、池田俊也、天野託、原明義
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] 国際医療福祉大学薬学部における新しい尿検査実習の試み2012
- Author(s)
  中谷善彦、大出浩子、宮川和也、竹内智子、横山秀克、天野託、原明義
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] 抑肝散のセロトニン神経系細胞株B65の増殖機能に及ぼす影響2012
- Author(s)
  中谷　善彦、天野　託、辻　稔、武田　弘志
- Organizer
  第42回日本神経精神薬理学会年会
- Place of Presentation
  栃木県総合文化センター（宇都宮）
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] 抑肝散のセロトニン神経系細胞株B65 の増殖機能に及ぼす影響2012
- Author(s)
  中谷善彦、天野託、辻稔、武田弘志
- Organizer
  第42回日本神経精神薬理学会年会
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] 抑肝散のセロトニン神経系細胞株B65の増殖機能に及ぼす影響2012
- Author(s)
  中谷　善彦、天野　託、辻　稔、武田　弘志
- Organizer
  第42回日本神経精神薬理学会年会
- Place of Presentation
  栃木県総合文化センター
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] グルココルチコイドがグリア細胞およびミクログリア細胞に与える影響-2012
- Author(s)
  中谷　善彦、辻　稔、宮川　和也、天野　託
- Organizer
  第2回国際医療福祉大学学会学術大会
- Place of Presentation
  国際医療福祉大学
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] 新規標的分子による視床ニューロンNa+チャネルを介する鎮痛作用機序の解明2012
- Author(s)
  天野　託、中谷　善彦、辻　稔、宮川　和也
- Organizer
  第2回国際医療福祉大学学会学術大会
- Place of Presentation
  国際医療福祉大学
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] 国際医療福祉大学薬学部における血圧測定の応用実習(第4報)-カフェインの急性昇圧作用に及ぼすコーヒーと茶類の飲用習慣の影響-2012
- Author(s)
  大出浩子、宮川和也、中谷善彦、竹内智子、横山秀克、天野託、原明義
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] グリア細胞増殖に及ぼすコルチコステロンの影響とその特徴2011
- Author(s)
  中谷善彦、天野託、宮川和也、加藤英明、辻稔、武田弘志
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] 国際医療福祉大学薬学部における血圧測定の応用実習(第3 報)-カフェインの血圧上昇作用-2011
- Author(s)
  大出浩子、宮川和也、竹内智子、中谷善彦、横山秀克、天野託、原明義
- Organizer
  日本薬学会第131 年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] オランザピン服用者のインスリン上昇と脂質代謝異常2011
- Author(s)
  天野託
- Organizer
  第21回日本臨床精神神経薬理学会・第41回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] 慢性ストレス負荷がアルコール依存形成に及ぼす影響2011
- Author(s)
  加藤英明、辻稔、天野託、武田弘志
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] オランザピン服用患者における糖負荷試験後のインスリン分泌の増加2010
- Author(s)
  天野託
- Organizer
  第106回日本精神神経学会学術総会
- Place of Presentation
  広島国際会議場(広島県)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] オランザピン服用患者における糖負荷試験後のインスリン分泌の増加2010
- Author(s)
  天野託、高見浩、箱守英雄、織田一衛、森川龍一
- Organizer
  第106回日本精神神経学会学術総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-22600014
[Presentation] Herbal medicine Goshajinkigan and Rokumigan inhibit Nav1.7 voltage-gated sodium channel current
- Author(s)
  中谷善彦、宮川和也、辻　稔、武田弘志、天野　託
- Organizer
  第88回日本薬理学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26460703

1. MATSUBAYASHI Hiroaki (60165850)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. SAKAI Norio (70263407)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. NAKATANI Yoshihiko (40582169)

# of Collaborated Projects: 4 results

# of Collaborated Products: 28 results
4. SEKI Takahiro (50335650)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TSUJI Minoru (70297307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. MIYAGAWA Kazuya (10453408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. KATOH Hideaki (30438220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. HIROMICHI NAKABAYASHI (70346716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAKAKIBARA IWAO (50581972)

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10. YAHAGI TADAHIRO (40632766)

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11. FUJITA KYOKO (20406169)

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12. SASA Masashi (20025654)

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13. ISHIHARA Kumatoshi (20212912)

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14. SERIKAWA Tadao (30025655)

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15. TAMURA Yutaka (30217202)

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16. 白井康仁 (60263399)

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17. 斎藤尚亮 (60178499)

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18. 遠藤加奈子 (20642416)

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19. 松浦利江子 (50535995)

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20. 石本豪 (70440469)

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21. 瀬戸口ひとみ (90594391)

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22. 谷田部佳代弥 (90458331)

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23. 坪倉繁美 (00521303)

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24. 岸浩一郎 (50161435)

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25. 大塚尚 (60735075)

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26. YOSHIZAWA SACHIKO

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27. OOKADO FUMI

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28. MASHIKO KIMI

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AMANO Taku 天野 託

Research Projects

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Elucidation of pain control mechanism via sodium channel of novel target molecule contained in herbal medicine GoshajinkiganPrincipal Investigator

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The function of Na^+channel as a novel target molecule for chronic pain treatment in thalamus neuronPrincipal Investigator

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メタアンフェタミン反復投与によるドーパミンニューロンの機能変化に関する研究Principal Investigator

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[Journal Article] Yokukansan enhances the proliferation of B65 neuroblastoma.2017

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[Journal Article] Yokukansan enhances the proliferation of B65 neuroblastoma.2016

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[Journal Article] Corticosterone Inhibits the Proliferation of C6 Glioma Cells via the Translocation of Unphosphorylated Glucocorticoid Receptor2016

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[Journal Article] Yokukansan enhances the proliferation of B65 neuroblastoma2016

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[Journal Article] Neuroprotective effect of yokukansan against cytotoxicity induced by corticosterone on mouse hippocampal neurons.2014

AMANO Taku 天野託