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SASA Masashi
笹 征史
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Researcher Number
20025654
External Links
Affiliation
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1997 – 2001 : 広島大, 医学部, 教授
1992 – 2001 : 広島大学, 医学部, 教授
1986 – 1991 : 京都大学, 医学部, 助教授
1986 : 京大, 医学部, 助教授
Review Section/Research Field
Principal Investigator
General pharmacology
/
応用薬理学・医療系薬学
Except Principal Investigator
General pharmacology
/
Neurology
Keywords
Principal Investigator
自然発症てんかんラット / 欠神様発作 / 強直性けいれん / ノルアドレナリン / 青斑核 / 自然発症てんかんラット(SER) / カルシウムチャネル / Ca^<2+> channel / トレモアラット / 抗てんかん薬
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/ ド-パミン / バルブロ酸 / absence-like seizure / ホルボルエステル / フェノバルビタール / 膀胱 / Absence-like seizure / tonic convulsion / 黒質 / tremor rat / CNK-602A / SER / パッチクランプ法 / α_1受容体 / 麻酔薬 / vaporate / 聴原性発作 / 排尿 / tm因子 / 上行性ニューロン / 長期摂取 / Fura2-AM / CaィイD12+ィエD1 channel / 側坐核 / Spontaneously epileptic rat / てんかん発作 / ド-パミンニュ-ロン / Spontaneously epileptic rat (SER) / long-term-intake / フェノバール / カルシウムチャンネル / 発作自動記録 / epileptic seizure / 尾状核ニューロン / Ca^<2+> channel abnormality / 音刺激プライミング / N-アセチルアスパルテート(NAA) / 強直-間代性けいれん / 高電位棘波群発 / hippocampal CA3 / アスパルトアセチレース遺伝子 / トリメサジオン / 海馬CA3ニューロン / Ca^<2+>チャネル異常 / EEG Absence-like seizure / 海馬CA3 / Phenobarbital / ASP遺伝子 / 腹側被蓋野 / Tonic convulsion / 延命効果 / 長期摂取効果 / プロテインキナーゼC / antiepileptic drug / N-acetyl aspartate / てんかんモデル動物 / Epilepsy / 5-HT_<1A>レセプター / spontaneously epileptic rat / Spontaneously epileptic rat(SER) / 音誘発発作 / アスパルトアセチラーゼ / パッチクランプホールセル記録 / Tremor rat / metabotropic glutamate receptor / 音振幅スパイク / エトスキサミド / アセチルコリン / 高振幅スパイク / パッチクランプ / 軸索内記録 / SCH23390 / 前庭一次求心神経 / ホールセル記録 / 前庭眼反射 / TRH / 脱分極シフト / a double mutant / GABA_A受容体 / NMDA / 前庭神経内側核ニュ-ロン / spontaneously epileptic rat (SER) / 強直性けいれん発作 / tm gene / 仙髄排尿中枢 / 水平半規管 / AMPA / プロティンキン-ゼC / 血中濃度 / autosomal recessive gene / Kyo:Wistarラット / キスカル酸 / てんかん / チッターラット / 前庭神経内側核 / ノダてんかんラット(NER) / 遺伝子解析 / フェニトイン / acoustic priming / phenobarbital / nifedipine / カルシウムイオンチャンネル / ニカルジピン / 前庭神経核 / audiogenic seizure / バルプロ酸(VPA) / Noda epileptic rat (NER) / エタノール / plasma concentration of drug / ドンペリドン / Hippocampal pyramidal cell / 脳波 / グルタミン酸 / カテコラミン / カルシウム電流 / Spontaneously epileptic rats / Antiepileptics / fura2 / TRH analogue / Syb2 / 代謝型グルタミン酸受容体 / グルタミン酸レセプタ- / dopamine / aspartoacetylase gene / カルシウム拮抗薬 / depolarization shift / 海馬錐体細胞 / セロトニン / zitter rat / 8-OHDPAT / ノダてんかんラット / ホールセルパッチクランプ / 副腎クロマフィン細胞 / Ca^<2+> antagonist / aspartpacetylase / fura / アスパルトアセチレース / calcium influx / epileptic model animal / GABA_A receptor / ニフェジピン / tremorラット / 長期効果 / Ca^<2+>チャネル / 常染色体劣性遺伝 / 単離ニューロン / カルシウム流入 / N-アセチルアスパルテート / 血漿中濃度 / キンピロ-ル / prolongation of survival / high-amplitude spike / トピラメート / マイクロイオントホレーシス / てんかん様発作 / 海馬CA3細胞 / 自発発火 / Zitterラット / フェノバルビタ-ル / 単離ニュ-ロン / TRH類緑体 / カイニン酸 / 視運動眼振 / パルプロ酸 / ド-パミンD-2受容体 / プラゾシン / SKF38393 / Tremorラット
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More
Except Principal Investigator
Caudate nucleus / 尾状核 / グルタミン酸 / ドーパミン / 細胞内記録 / グルタミン酸輸送蛋白 / 海馬 / L-2-(carboxycyclopropyl)-glycine / 前頭葉 / 小脳 / ドーパミン受容体 / アルツハイマー病 / Intracellular recording / パーキンソン病 / エルゴット・アルカロイド / Dopamine receptor / Vestibular nucleus / 細胞死 / 副腎髓質クロマフィン細胞 / Tachykinin / 側坐核 / コリン作動系 / 神経細胞死 / Muscarinic receptors / Serotonin / 薬物療法 / EPDP / GABA受容体 / Patch clam method / 薬物受容体 / ムスカリン性受容体 / Central neuron / bromocriptine / Electric signals of nerve cells / Endothelin / ブロモクリプチン / Dopamine / Softwares / 中枢ニューロン / アボリポ蛋白E / reverse transpot / カリウムイオンチャンネル / Alzheimer's disease / ソフトウエア / ドーパミン輸送蛋白 / ドパミン / Software for analysis of electric signals / dot blot hybridization / クロマフィン細胞 / Analysis of electrical signals / neuronal death / アルツハイマー型痴呆 / ニコチン / Muscarinic receptor / プレセニリン / 波形解析 / 神経変性疾患 / Nicotine / 老人班 / 一酸化窒素(NO) / エルゴタミン / 電気信号解析用ソフトウェア / ナトリウム / ソフトウェア / Adrenal chromaffin cell / HeLa細胞 / 一本鎖DNA高次構造多型 / 前庭神経核 / Dopamine D-2 receptor / Nucleus accumbens / GLT1 / エタノール / ドンペリドン / 神経細胞電気信号 / ド-パミンDー2受容体 / ブロモクロプチン / ド-パミン受容体 / タウ蛋白 / Bromocriptine / タキキニン受容体 / 副腎髄質 / 連鎖不平衡 / glutamic acid / Nitric Oxide / アミノ酸麦角アルカロイド / GluT1 / Acetylcholine / GABA receptor / セロトニン / L-(カルボキシシクロプロピル)グリシン / ergotamine / sodium ion / 直接塩基配列決定法 / Dopaminergic system / 神経原線維変化 / アセチルコリン / エンドセリン / GluT-1 / 海馬CA1領域 / uNIX / Ethanol / 電気信号波形解析 / ムスカリン受容体 / Depamine / イオントホレシス / パッチクランプ法 / Methamphetamine / 遺伝子多型 / Potassium ion channel / ハロペリドール / 細胞電気信号 / メタンフェタミン / カリウムチャネル / β-アミロイド蛋白 / glutamate transporter / Parkinson's disease / ドーパミン作動系 / EPSP / Drug Receptor
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Research Projects
(
27
results)
Co-Researchers
(
31
People)
Project Start Year(Newest)
Project Start Year(Oldest)
Pharmacological research on Ca^<2+> channel abnormality which induces epileptic seizures
Principal Investigator
Principal Investigator
SASA Masashi
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
General pharmacology
Research Institution
HIROSHIMA UNIVERSITY
神経細胞死予防のためのグルタミン酸・ドーパミン輸送蛋白の研究
Principal Investigator
中村 重信
Project Period (FY)
1999
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Hiroshima University
神経細胞死予防のためのグルタミン酸輸送蛋白の薬理学的研究
Principal Investigator
中村 重信
Project Period (FY)
1998
Research Category
Grant-in-Aid for Scientific Research on Priority Areas (A)
Research Institution
Hiroshima University
アルツハイマー型痴呆の病態と治療に関する基礎研究
Principal Investigator
鍋島 俊隆
Project Period (FY)
1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
General pharmacology
Research Institution
Nagoya University
Development of preventive drugs for neurodenerative diseases through glutamate tranporter.
Principal Investigator
NAKAMURA Shigenobu
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Neurology
Research Institution
Hiroshima University
神経変性疾患におけるグルタミン酸輸送蛋白の薬理学的研究
Principal Investigator
NAKAMURA Shigenobu
Project Period (FY)
1997
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hiroshima University
Pharmacological research on CaィイD12+ィエD1 channel abnormality which induces epileptic seizures.
Principal Investigator
Principal Investigator
SASA Masashi
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
General pharmacology
Research Institution
Hiroshima University
Development and pharmacological application of a newly genetic epilepsy rat (NER)
Principal Investigator
Principal Investigator
SASA Masahi
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
応用薬理学・医療系薬学
Research Institution
HIROSHIMA UNIVERSITY
Production under control of microorganism and pharmacological use of spontaneously epileptic rats.
Principal Investigator
Principal Investigator
SASA Masashi
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
応用薬理学・医療系薬学
Research Institution
HIROSHIMA UNIVERSITY
Drug receptor function and its regulation
Principal Investigator
TODA Noboru
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
General pharmacology
Research Institution
Shiga University of Medical Science
前庭神経核ニューロンに対する縫線核由来セロトニン性抑制機構の解明
Principal Investigator
Principal Investigator
笹 征史
Project Period (FY)
1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Hiroshima University
Establishment of newly found tremor rat as absence seizure model and pharmacological usefulness
Principal Investigator
Principal Investigator
SASA Masashi, 笹征 史
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
応用薬理学・医療系薬学
Research Institution
HIROSHIMA UNIVERSITY
単離前庭神経内側核ニュ-ロンにおけるグルタミン酸レセプタ-の証明
Principal Investigator
Principal Investigator
笹 征史
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto University
腹側被蓋野ド-パミンニュ-ロンにおけるDー1とDー2レセプタ-の役割および相互作用
Principal Investigator
Principal Investigator
笹 征史
Project Period (FY)
1990
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto University
Establishment of evaluation of long-term effects of antiepileptic drugs in the spontaneously epileptic rat
Principal Investigator
Principal Investigator
SASA Masashi
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
応用薬理学・医療系薬学
Research Institution
Kyoto University
Development of Software for Automatic Analysis of Electric Signals of the Nerve Cells Recorded by Patch Clamp Method
Principal Investigator
TAKAORI Shuji
Project Period (FY)
1989 – 1990
Research Category
Grant-in-Aid for Developmental Scientific Research (B).
Research Field
General pharmacology
Research Institution
Kyoto University
中枢排尿機構における青斑核由来ノルアドレナリンと黒質由来ド-パミンの相互作用
Principal Investigator
Principal Investigator
笹 征史
Project Period (FY)
1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto University
前庭神経核細胞の自動能におけるプロテインキナ-ゼCの役割に関する電気生理学的研究
Principal Investigator
Principal Investigator
笹 征史
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto University
仙髄排尿中枢ニューロンに対する青斑核由来ノルアドレナリンの興奮作用
Principal Investigator
Principal Investigator
笹 征史
Project Period (FY)
1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto University
尾状核ニューロン活動におけるプロテインキナーゼCの役割に関する電気生理学的研究
Principal Investigator
Principal Investigator
笹 征史
Project Period (FY)
1988
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto University
Specificity of function of acetylcholinergic receptors in the caudate and vestibular nuclei.
Principal Investigator
TAKAORI Shuji
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
General pharmacology
Research Institution
KYOTO UNIVERSITY
Establishment of long-term maintenance of the spontaneously epileptic rats and their pharmacological use
Principal Investigator
Principal Investigator
SASA Masashi
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
応用薬理学・医療系薬学
Research Institution
KYOTO UNIVERSITY
青斑核由来ノルアドレナリンによる膀胱機能の調節機構
Principal Investigator
Principal Investigator
笹 征史
Project Period (FY)
1987
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto University
前庭一次求心系に対するエタノールおよび各種麻酔薬の作用に関する研究
Principal Investigator
Principal Investigator
笹 征史
Project Period (FY)
1986
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General pharmacology
Research Institution
Kyoto University
Studies on development of softwares to analyze electrical signals from neurons in the central nervous system.
Principal Investigator
TAKAORI Shuji
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
General pharmacology
Research Institution
Kyoto University
Development of spontaneously epileptic rat and pharmacological application of the rat.
Principal Investigator
Principal Investigator
SASA Masashi
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
応用薬理学・医療系薬学
Research Institution
Kyoto University
Uniformity and specificity of function of monoaminergic receptors in the caudate nucleus and nucleus accumbens
Principal Investigator
TAKAORI Shuji
Project Period (FY)
1985 – 1987
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
General pharmacology
Research Institution
Kyoto University
# of Projects (Dsc)
# of Projects (Asc)
1.
SERIKAWA Tadao
(30025655)
# of Collaborated Projects :
8results
# of Collaborated Products :
0results
2.
ISHIHARA Kumatoshi
(20212912)
# of Collaborated Projects :
8results
# of Collaborated Products :
0results
3.
MATSUBAYASHI Hiroaki
(60165850)
# of Collaborated Projects :
5results
# of Collaborated Products :
0results
4.
AKAIKE Akinori
(80135558)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
5.
UJIHARA Hisamitsu
(00213421)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
6.
NAKAMURA Shigenobu
(30026843)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
7.
KAWAKAMI Hideshi
(70253060)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
8.
TAKAORI Shuji
(10025538)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
9.
YAMADA Junzo
(90025651)
# of Collaborated Projects :
4results
# of Collaborated Products :
0results
10.
片山 禎夫
(00211160)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
11.
HARA Mitsuyoshi
(50192282)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
12.
MOMIYAMA Toshihiko
(20230055)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
13.
TODA Noboru
(50025590)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
14.
TAKAYANAGI Issei
(70012599)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
15.
ABIKO Yasushi
(90041821)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
16.
SAITO Hideya
(20000929)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
17.
KURIYAMA Kinya
(20079734)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
18.
KOHNO Shizuko
(30034028)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
19.
AMANO Taku
(10294547)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
20.
FUJIWARA Motokazu
(60093308)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
21.
鍋島 俊隆
(70076751)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
22.
妹尾 久雄
(40135380)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
23.
米田 幸雄
(50094454)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
24.
田平 武
(80112332)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
25.
武田 雅俊
(00179649)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
26.
丸山 博文
(90304443)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
27.
加藤 隆一
(40112685)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
28.
YAMAMOTO Toshiyuki
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
29.
NODA Atsushi
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
30.
MIYAMOTO Masaomi
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
31.
笹征 史
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
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