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ISHII MASARU  石井 優

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ISHII Masaru  石井 優

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Researcher Number 10324758
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Affiliation (Current) 2025: 大阪大学, 大学院生命機能研究科, 教授
2025: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 創薬デザイン研究センター, 招へいプロジェクトリーダー
Affiliation (based on the past Project Information) *help 2021 – 2024: 大阪大学, 大学院生命機能研究科, 教授
2013 – 2021: 大阪大学, 生命機能研究科, 教授
2018: 大阪大学, 大学院生命機能研究科, 教授
2016: 大阪大学, 大学院医学系研究科, 教授
2014: 大阪大学, 大学院・生命機能研究科, 教授 … More
2014: 大阪大学, 大学院医学系研究科, 教授
2013: 大阪大学, 大学院医学系研究科・医学部, 教授
2011 – 2012: 大阪大学, 免疫学フロンティア研究センター, 特任教授
2010: Osaka University, その他
2009 – 2010: National Hospital Organization Osaka-Minami Medical Center, 免疫学フロンティア研究センター, 特任准教授
2009: 大阪南医療センター(臨床研究部), 免疫異常疾患研究所, 研究員
2008: National Hospital Organization Osaka-Minami Medical Center, 免疫異常疾患研究室, 主任研究員
2006: 大阪南医療センター
2005: Osaka University, Graduate School of Medicine, Assistant professor, 免疫異常疾患研究所, 研究員
2005: 独立行政法人国立病院機構(大阪南医療センター臨床研究部), 免疫異常疾患研究室, 研究員
2000 – 2004: Osaka University Graduate School of Medicine, Assistant Professor, 医学系研究科, 助手 Less
Review Section/Research Field
Principal Investigator
General pharmacology / Biological Sciences / 膠原病・アレルギー・感染症内科学 / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Transformative Research Areas, Section (III) / Medium-sized Section 52:General internal medicine and related fields / Broad Section I / Collagenous pathology/Allergology / General pharmacology
Except Principal Investigator
Functional basic dentistry … More / Biological Sciences / Biological Sciences / Transformative Research Areas, Section (III) / Life / Health / Medical informatics / General physiology / General pharmacology / System genome science / Biological Sciences Less
Keywords
Principal Investigator
医療・福祉 / 関節リウマチ / 破骨細胞 / 細胞動態 / ケモカイン / イメージング / マクロファージ / 生体イメージング / カルモデュリン / 炎症性骨破壊 … More / 免疫学 / 免疫・炎症 / 関節炎 / 骨髄環境 / 骨代謝 / 骨粗鬆症 / 脂質メディエーター / トランスレーショナルリサーチ / 薬理学 / シグナル伝達 / 細胞・組織 / FRET / RGS蛋白質 / G蛋白質サイクル / G蛋白質制御カリウムチャネル / 末梢神経 / 神経関連マクロファージ / イメージング「 / 炎症 / 免疫 / 骨破壊 / リウマチ学 / ニッチ / 細胞分化 / がん幹細胞 / がん細胞 / 骨髄 / ケモタキシス / 細胞内局在 / エンドサイトーシス / ケモカイン受容体 / イノシトールリン脂質 / 脂質ラフト / 脂質マイクロドメイン / G蛋白質シグナル / ホスホリン脂質 / RGS蛋白 / 膜興奮 / カルシウム … More
Except Principal Investigator
FRET / 生体イメージング / グリア / 内向き整流性カリウムチャネル / 細胞遊走 / 細胞追跡 / イメージング / 蛍光イメージング / 脂質ラフト / 数理モデル / カリウムチャネル / RGS蛋白質 / G蛋白質 / 免疫疾患 / 免疫寛容 / 体内環境 / 脳末梢連関 / 神経回路 / バイオインフォマティクス / 炎症反応 / 免疫細胞 / 細胞動態 / 脂肪細胞 / 細胞イメージング解析 / セグメンテーション / イメージング解析 / 細胞イメージング / 受容体拮抗薬 / 赤血球 / 骨吸収 / アディポネクチン / ニコランジル / NO / 活性酸素 / 分化 / 破骨細胞 / S1P / 活性脂質 / Lipid raft / Calmodulin / PDZ protein / RGS protein / G protein-gated potassium channel / カルモデュリン / カルモディリン / G蛋白質制御カリウムチャネル / 蛍光エネルギー共鳴移動法 / カルモジュリン / PDZ蛋白質 / G蛋白制御カリウムチャネル / Glial cells / Kidney / homeostasis / Epithelial cells / Water channels / Inwardly rectifying K+ channels / グリア細胞 / 内向き整流カリウムチャネル / 腎臓 / ホメオスターシス / 上皮細胞 / 水チャネル / Cardio-vascular system / Potassium channel Opener / Sulfonylurea receptor / ATP-sensitive potassium channel / Inwardly rectifying potassium channel / チャネル制御機構 / チャネル開口剤 / 膜2回貫通型カリウムチャネル / スルホニルウレア受容体 / 循環器系 / チャネル開口薬 / スルフォニルウレア受容体 / ATP感受性カリウムチャネル / モデル化とシミュレーション / 細胞トラッキング / バイオイメージインフォマティクス / 画像処理 / 細胞画像解析 / 骨吸収治療薬 / 骨代謝 / グラム陽性菌 / 歯周病 / 免疫 / 炎症 / 骨代謝治療薬 / 自然免疫 / in vivo imaging / Toll-like receptor / 炎症性骨破壊 / 緑色蛍光タンパク質 / 超解像度イメージング / 二光子顕微鏡 / ケミカルバイオロジー / ライブイメージング / 国際研究者交流 / 国際情報交換 / 蛍光生体イメージング / がん / 細胞生物 / 蛍光プローブ / 蛍光タンパク質 / 細胞生物学 / 蛍光顕微鏡 / 脂質代謝 / 心臓生理 / シミュレーション / イオンチャネル / シミユレーション / カルシウムシグナル / 細胞内シグナル Less
  • Research Projects

    (24 results)
  • Research Products

    (186 results)
  • Co-Researchers

    (45 People)
  •  線維化誘導性マクロファージの同定と標的とした新規治療法開発Principal Investigator

    • Principal Investigator
      石井 優
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      Osaka University
  •  Reestablishing immune tolerance and homeostasis in autoimmune and autoinflammatory diseases

    • Principal Investigator
      竹田 潔
    • Project Period (FY)
      2022 – 2028
    • Research Category
      Fund for the Promotion of Joint International Research (International Leading Research )
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Glia decoding: deciphering information critical for brain-body interactions

    • Principal Investigator
      岡部 繁男
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      The University of Tokyo
  •  Dynamic control of immune and inflammatory cell behavios by peropheral nervous systemPrincipal Investigator

    • Principal Investigator
      石井 優
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Osaka University
  •  Identification and control of pathogenic osteoclastsPrincipal Investigator

    • Principal Investigator
      Ishii Masaru
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section I
    • Research Institution
      Osaka University
  •  Identification and conotrol of pathogenic osteoclastsPrincipal Investigator

    • Principal Investigator
      石井 優
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Osaka University
  •  Establishment of in vivo immunopharmacologyPrincipal Investigator

    • Principal Investigator
      ISHII MASARU
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  Comprehensive and Systematic Analysis of Cell Migration Dynamics by Real-Time Bioimaging

    • Principal Investigator
      MATSUDA Hideo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Life / Health / Medical informatics
    • Research Institution
      Osaka University
  •  Development of novel methods for evaluating RA pathogenesis and activityPrincipal Investigator

    • Principal Investigator
      ISHII Masaru
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Osaka University
  •  Effect of lipid mediators on osteoclast differentiation

    • Principal Investigator
      AMANO Hitoshi
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Osaka Dental University
      Showa University
  •  Dynamic analysis for living cell environment by 4D imaging

    • Principal Investigator
      MATSUDA Hideo
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      System genome science
    • Research Institution
      Osaka University
  •  Regulation of inflammation and innate immunity by TLR agonists

    • Principal Investigator
      SUZUKI Keiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Showa University
  •  Multi-dimensional fluorescent live imaging of cellular functions and molecular activities

    • Principal Investigator
      MICHIYUKI Matsuda
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Intravital imaging of bone cell physiology and bone-resident cancersPrincipal Investigator

    • Principal Investigator
      ISHII Masaru
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Systematic analyses of modes of migration, differentiation andfunction of bone-resorbing osteoclasts visualized by intravitalimagingPrincipal Investigator

    • Principal Investigator
      ISHII Masaru
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Osaka University
  •  細胞内ロジスティクスによる破骨細胞の遊走・機能の生理的制御機構の解明Principal Investigator

    • Principal Investigator
      石井 優
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Dynamic in vivo imaging of osteoclast functions for development of novel therapeutics against bone-resorptive disordersPrincipal Investigator

    • Principal Investigator
      ISHII Masaru
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      National Hospital Organization Osaka-Minami Medical Center
  •  Physiological regulation of G protein signaling by RGS proteins

    • Principal Investigator
      KURACHI Yoshihisa
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  膜マイクロドメインでの脂質・蛋白質間相互作用によるG蛋白質シグナルの生理的制御Principal Investigator

    • Principal Investigator
      石井 優
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      National Hospital Organization Osaka-Minami Medical Center
  •  RGS蛋白質による三量体G蛋白質サイクルの生理的制御機構の解明Principal Investigator

    • Principal Investigator
      石井 優
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  Molecular mechanisms for functional and spatial regulation of the G protein-gated potassium channel

    • Principal Investigator
      KURACHI Yoshihisa
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General physiology
    • Research Institution
      Osaka University
  •  G蛋白質制御カリウムチャネルの生理的活性調節機構の解析Principal Investigator

    • Principal Investigator
      石井 優
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  The physiological roles and molecular basis of polarized localization of K+ channels in the vectorial transports of ions and water.

    • Principal Investigator
      KURACHI Yoshihisa
    • Project Period (FY)
      2000 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Regulation of cardio-vascular ATP-sensitive K channels.

    • Principal Investigator
      KURACHI Yoshihisa
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2006 2005 2004 2003 2002 2001 Other

All Journal Article Presentation Book Patent

  • [Book] Chronic Inflammation2016

    • Author(s)
      Kikuta J, Ishii M
    • Total Pages
      695
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-16H02619
  • [Book] 別冊・医学の歩み( HERGチャネルとKCNQ1/KCNE1チャネル)2005

    • Author(s)
      石井優, 倉智嘉久
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-17079005
  • [Book] イオンチャネル最前線update2005

    • Author(s)
      石井 優
    • Total Pages
      7
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-17079005
  • [Book] Encyclopedia of Endocrinology and Endocrine Diseases2004

    • Author(s)
      Ishii M, et al.
    • Total Pages
      3043
    • Publisher
      Academic Press
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] Group 2 innate lymphoid cells support hematopoietic recovery under stress conditions2021

    • Author(s)
      Sudo Takao、Motomura Yasutaka、Okuzaki Daisuke、Hasegawa Tetsuo、Yokota Takafumi、Kikuta Junichi、Ao Tomoka、Mizuno Hiroki、Matsui Takahiro、Motooka Daisuke、Yoshizawa Ryosuke、Nagasawa Takashi、Kanakura Yuzuru、Moro Kazuyo、Ishii Masaru
    • Journal Title

      Journal of Experimental Medicine

      Volume: 218 Issue: 5 Pages: 20200817-20200817

    • DOI

      10.1084/jem.20200817

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08356, KAKENHI-ORGANIZER-20H05894, KAKENHI-PLANNED-20H05901, KAKENHI-PROJECT-18H05286, KAKENHI-PROJECT-19H05657, KAKENHI-PROJECT-18K08355, KAKENHI-PROJECT-20K17378, KAKENHI-PROJECT-18H03998, KAKENHI-PROJECT-21K08415, KAKENHI-PROJECT-20K16192
  • [Journal Article] Retrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis2021

    • Author(s)
      Ishii M, Tateya T, Matsuda M, Hirashima T.
    • Journal Title

      eLife

      Volume: 10 Pages: 1-16

    • DOI

      10.7554/elife.61092

    • NAID

      120006976053

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-20H05894, KAKENHI-PROJECT-19H00993, KAKENHI-PROJECT-19K09887
  • [Journal Article] SLPI is a critical mediator that controls PTH-induced bone formation2021

    • Author(s)
      Morimoto Akito、Kikuta Junichi、Nishikawa Keizo、Sudo Takao、Uenaka Maki、Furuya Masayuki、Hasegawa Tetsuo、Hashimoto Kunihiko、Tsukazaki Hiroyuki、Seno Shigeto、Nakamura Akira、Okuzaki Daisuke、Sugihara Fuminori、Ninomiya Akinori、Yoshimura Takeshi、Takao-Kawabata Ryoko、Matsuda Hideo、Ishii Masaru
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 2136-2136

    • DOI

      10.1038/s41467-021-22402-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K22938, KAKENHI-ORGANIZER-20H05894, KAKENHI-PLANNED-20H05901, KAKENHI-PROJECT-19H05657, KAKENHI-PROJECT-18H02614, KAKENHI-PROJECT-20K17378, KAKENHI-PROJECT-21H02716, KAKENHI-PROJECT-20K09719
  • [Journal Article] Geometry and the Organizational Principle of Spine Synapses along a Dendrite2020

    • Author(s)
      Parajuli Laxmi Kumar、Urakubo Hidetoshi、Takahashi-Nakazato Ai、Ogelman Roberto、Iwasaki Hirohide、Koike Masato、Kwon Hyung-Bae、Ishii Shin、Oh Won Chan、Fukazawa Yugo、Okabe Shigeo
    • Journal Title

      eneuro

      Volume: 7 Issue: 6 Pages: 0248-20

    • DOI

      10.1523/eneuro.0248-20.2020

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07743, KAKENHI-PROJECT-20K12062, KAKENHI-PUBLICLY-20H05058, KAKENHI-ORGANIZER-20H05894, KAKENHI-PLANNED-20H05895, KAKENHI-PROJECT-20H00481, KAKENHI-PROJECT-19H03323, KAKENHI-PROJECT-17K00404, KAKENHI-PROJECT-19K22469, KAKENHI-PROJECT-18K14842, KAKENHI-PROJECT-18K06499
  • [Journal Article] In vivo visualization of different modes of action of biologic DMARDs inhibiting osteoclastic bone resorption.2018

    • Author(s)
      Matsuura Y, Kikuta J, Kishi Y, Hasegawa T, Okuzaki D, Hirano T, Minoshima M, Kikuchi K, Kumanogoh A, Ishii M
    • Journal Title

      Annals of the Rheumatic Diseases

      Volume: in press

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02619
  • [Journal Article] Direct cell-cell contact between mature osteoblasts and osteoclasts dynamically controls their functions in vivo2018

    • Author(s)
      Masayuki Furuya、Junichi Kikuta、Sayumi Fujimori、Shigeto Seno、et.al
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 300-300

    • DOI

      10.1038/s41467-017-02541-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K00403, KAKENHI-PROJECT-17K11005, KAKENHI-PROJECT-16K12525, KAKENHI-PROJECT-15H05671, KAKENHI-PROJECT-16H02619
  • [Journal Article] Intravital Imaging of Liver Cell Dynamics2018

    • Author(s)
      Matsumoto S, Kikuta J, Ishii M
    • Journal Title

      Methods in Molecular Biology

      Volume: 1763 Pages: 137-143

    • DOI

      10.1007/978-1-4939-7762-8_13

    • ISBN
      9781493977611, 9781493977628
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05815, KAKENHI-PROJECT-16H02619
  • [Journal Article] Bone marrow cavity segmentation using graph-cuts with wavelet-based texture feature2017

    • Author(s)
      Shigeta Hironori、Mashita Tomohiro、Junichi Kikuta、Shigeto Seno、et.al
    • Journal Title

      Journal of Bioinformatics and Computational Biology

      Volume: 15 Issue: 05 Pages: 1740004-1740004

    • DOI

      10.1142/s0219720017400042

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K00403, KAKENHI-PROJECT-16K12525
  • [Journal Article] Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions2017

    • Author(s)
      Matsui Takahiro、Mizuno Hiroki、Sudo Takao、Kikuta Junichi、Haraguchi Naotsugu、Ikeda Jun-ichiro、Mizushima Tsunekazu、Yamamoto Hirofumi、Morii Eiichi、Mori Masaki、Ishii Masaru
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 6959-6959

    • DOI

      10.1038/s41598-017-07244-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08649, KAKENHI-PROJECT-17K19555, KAKENHI-PROJECT-16H02619
  • [Journal Article] TRPM2 channels in alveolar epithelial cells mediate bleomycin-induced lung inflammation2016

    • Author(s)
      Yonezawa R, Yamamoto S, Takenaka M, Kage Y, Negoro T, Toda T, Ohbayashi M, Numata T, Nakano Y, Yamamoto T, Mori Y, Ishii M, Shimizu S
    • Journal Title

      Free Radic Biol Med

      Volume: 90 Pages: 101-113

    • DOI

      10.1016/j.freeradbiomed.2015.11.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09557, KAKENHI-PROJECT-25462899, KAKENHI-PROJECT-26460494, KAKENHI-PLANNED-26111004, KAKENHI-PROJECT-24249017, KAKENHI-PROJECT-15K08197
  • [Journal Article] グラフカットを用いた骨髄腔画像の領域分割2015

    • Author(s)
      宇佐見 潤, 繁田 浩功, 間下 以大, 黒田 嘉宏, 菊田 順一, 瀬尾 茂人, 石井 優, 松田 秀雄, 竹村 治雄
    • Journal Title

      情報処理学会論文誌 数理モデル化と応用

      Volume: 8 Pages: 18-27

    • NAID

      110009886640

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24651229
  • [Journal Article] Cell cycle-dependent Rho GTPase activity dynamically regulates cancer cell motility and invasion in vivo.2014

    • Author(s)
      Kagawa Y, Matsumoto S, Kamioka Y, Mimori M, Naito Y, Ishii T, Okuzaki D, Nishida N, Maeda S, Naito A, Kikuta J, Nishikawa K, Nishimura J, Haraguchi N, Takemasa I, Mizushima T, Ikeda M, Yamamoto H, Sekimoto M, Ishii H, Doki Y, Matsuda M, Kikuchi A, Mori M, Ishii M
    • Journal Title

      PLoS One

      Volume: 8 Issue: 12 Pages: e83629-e83629

    • DOI

      10.1371/journal.pone.0083629

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22113007, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-23701053, KAKENHI-PROJECT-25250018, KAKENHI-PROJECT-25253070, KAKENHI-PROJECT-25860211, KAKENHI-PROJECT-25893117
  • [Journal Article] Dynamic visualization of RANKL and Thl7-mediated osteoclast function.2013

    • Author(s)
      菊田 順一
    • Journal Title

      The journal of Clinical Investigation

      Volume: vol.123 Pages: 866-873

    • DOI

      10.1172/jci65054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J10335, KAKENHI-PLANNED-22113007, KAKENHI-PROJECT-22689030, KAKENHI-PROJECT-24750160, KAKENHI-PROJECT-25253070, KAKENHI-PROJECT-25650066, KAKENHI-PLANNED-21116002
  • [Journal Article] CognitionMaster: An Object-Based Image Analysis Framework2013

    • Author(s)
      Wienert S, Heim D, Kotani M, Lindequist B, Stenzinger A, Ishii M, Hufnagl P, Beil M, Dietel M, Denkert C, Klauschen F
    • Journal Title

      Diagn. Pathol

      Volume: 8 Pages: 34-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Sphingosine-1-phosphate signaling controlling osteoclasts and bone homeostasis2013

    • Author(s)
      Ishii M, Kikuta J
    • Journal Title

      Biochim Biophys Acta

      Volume: 1831(1) Pages: 223-227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Depletion of Jarid1b induces cellular senescence in human colorectal cancer2013

    • Author(s)
      Ohta K, Haraguchi N, Kano Y, Kagawa Y, Konno M, Nishikawa S, Hamabe A, Hasegawa S, Ogawa H, Fukusumi T, Uemura M, Nishimura J, Hata T, Takemasa I, Mizushima T, Noguchi Y, Ozaki M, Kudo T, Sakai D, Satoh T, Fukami M, Ishii M, Yamamoto H, Doki Y, Mori M, Is
    • Journal Title

      Int. J. Oncol

      Volume: 42(4) Pages: 1212-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Systemic circulation and bone recruitment of osteoclast precursors tracked by using fluorescent imaging techniques2013

    • Author(s)
      Kotani M, Kikuta J, Klauschen F, Chino T, Kobayashi Y, Yasuda H, Tamai K, Miyawaki A, Kanagawa O, Tomura M, Ishii M
    • Journal Title

      J. Immunol

      Volume: 190(2) Pages: 605-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] 混合正規分布モデルを用いた経時観測蛍光画像からの細胞核の検出と追跡手法2013

    • Author(s)
      瀬尾茂人, 間下以大, 前田栄, 竹中要一, 石井優, 松田秀雄
    • Journal Title

      情報処理学会論文誌 数理モデル化と応用

      Volume: 6(3) Pages: 140-150

    • NAID

      110009550153

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24651229
  • [Journal Article] Layer V cortical neurons require microglial support for survival during postnatal development2013

    • Author(s)
      Ueno M, Fujita Y, Tanaka T, Nakamura Y, Kikuta J, Ishii M, Yamashita T
    • Journal Title

      Nat. Neurosci

      Volume: 16(5) Pages: 543-51

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Dynamic visualization of RANKL and Th17-mediated osteoclast function2013

    • Author(s)
      Kikuta J, Wada Y, Kowada T, Wang Z, Sun-Wada G-H, Nishiyama I, Mizukami S, Maiya N, Yasuda H, Kumanogoh A, Kikuchi K, Germain RN, Ishii M
    • Journal Title

      J. Clin. Invest

      Volume: 123(2) Pages: 866-873

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Dynamic live imaging of bone: opening a new era with 'bone histodynametry'2013

    • Author(s)
      Ishii M, Fujimori S, Kaneko T, Kikuta J.
    • Journal Title

      J Bone Miner Metab

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] S1P-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D2013

    • Author(s)
      Kikuta J, Kawamura S, Okiji F, Shirazaki M, Sakai S, Saito H, Ishii M
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 110(17) Pages: 7009-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] S1P-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D.2013

    • Author(s)
      Kikuta J, Kawamura S, Okiji F, Shirazaki M, Sakai S, Saito H, Ishii M
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 110 Pages: 7009-7013

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Journal Article] S1P-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D.2013

    • Author(s)
      Kikuta J, Kawamura S, Okiji F, Shirazaki M, Sakai S, Saito H, Ishii M
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 110 Pages: 7009-7013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25253070
  • [Journal Article] Dynamic analysis of histamine-mediated attenuation of acetylcholine-induced sweating via GSK3beta activation2013

    • Author(s)
      Matsui S, Murota H, Takahashi A, Yang A, Lee J-B, Omiya K, Ohmi M, Kikuta J, Ishii M, Katayama I
    • Journal Title

      J. Invest. Dermatol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Osteoclast migration, differentiation, and function: novel therapeutic targets for rheumatic diseases2013

    • Author(s)
      Kikuta J, Ishii M
    • Journal Title

      Rheumatology

      Volume: 52(2) Pages: 226-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Recent advances in intravital imaging of dynamic biological systems2012

    • Author(s)
      Kikuta J, Ishii M.
    • Journal Title

      J. Pharmacol. Sci

      Volume: 119(3) Pages: 193-7

    • NAID

      10030986703

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Use of intravital microscopy and in vitro chemotaxis assays to study the roles of sphingosine-1-phosphate in bone homeostasis2012

    • Author(s)
      Ishii T, Kawamura S, Nishiyama I, Kikuta J, Ishii M
    • Journal Title

      Methods Mol. Biol.

      Volume: 874 Pages: 129-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] How do contemporaryimaging techniques contribute to basic and clinical rheumatology?2012

    • Author(s)
      Ishii M
    • Journal Title

      Ann. Rheum. Dis

      Volume: 71 (Suppl 2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice2012

    • Author(s)
      Fukuhara S, Simmons S, Kawamura S, Inoue A, Orba Y, Tokudome T, Sunden Y, Arai Y, Moriwaki K, Ishida J, Uemura A, Kiyonari H, Abe T, Fukamizu A, Hirashima M, Sawa H, Aoki J, Ishii M*, Mochizuki N*
    • Journal Title

      J. Clin. Invest

      Volume: 122(4) Pages: 1416-1426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Intestinal CX3C chemokine receptor 1high (CX3CR1high) myeloid cells prevent T-cell-dependent colitis2012

    • Author(s)
      Kayama H, Ueda Y, Sawa Y, Jeon SG, Ma JS, Okumura R, Kubo A, Ishii M, Okazaki T, Murakami M, Yamamoto M, Yagita H, Takeda K
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 109(13) Pages: 5010-5015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] The role of sphingosine 1-phosphate in migration of osteoclast precursors ; an application of intravital two-photon microscopy.2011

    • Author(s)
      Ishii, et al.
    • Journal Title

      Molecule and Cells

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] The role of sphingosine 1-phosphate in migration of osteoclast precursors ; an application of intravital two-photon microscopy.2011

    • Author(s)
      Ishii, et al.
    • Journal Title

      Molecule and Cells

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Journal Article] S1P-targeted therapy for elderly rheumatoid arthritis patients with osteoporosis2011

    • Author(s)
      Kikuta J, Iwai K, Saeki Y, Ishii M
    • Journal Title

      Rheumatol. Int

      Volume: 31 Pages: 967-969

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] PDGFRα-positive cells in bone marrow are mobilized by HMGB1 to regenerate injured epithelia2011

    • Author(s)
      Tamai K, Yamazaki T, Chino T, Ishii M, Otsuru S, Kikuchi Y, Iinuma S, Saga K, Nimura K, Shimbo T, Umegaki N, Katayama I, Miyazaki J, Takeda J, McGrath J, Uitto J, Kaneda Y.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 108(16) Pages: 6609-6614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] The role of sphingosine 1-phosphate in migration of osteoclast precursors; an application of intravital two-photon microscopy2011

    • Author(s)
      Ishii T, Shimazu Y, Nishiyama I, Kikuta J, Ishii M
    • Journal Title

      Mol. Cells

      Volume: 31(5) Pages: 399-403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] In vivo fluorescence imaging of bone-resorbing osteoclasts2011

    • Author(s)
      Kowada T, Kikuta, J, Kubo A, Ishii M, Maeda H, Mizukami S, Kikuchi K
    • Journal Title

      J. Am. Chem. Soc

      Volume: 33(44) Pages: 17772-17776

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] S1P-targeted therapy for elderly rheumatoid arthritis patients with osteoporosis.2011

    • Author(s)
      Kikuta, Ishii, et al.
    • Journal Title

      Rheumatology International

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] S1P-targeted therapy for elderly rheumatoid arthritis patients with osteoporosis.2011

    • Author(s)
      Kikuta, Ishii, et al.
    • Journal Title

      Rheumatology International

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Journal Article] Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo.2010

    • Author(s)
      Ishii, et al.
    • Journal Title

      Journal of Experimental Medicine

      Volume: 207 Pages: 2793-2798

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Journal Article] Intravital two-photon imaging: A versatile tool for dissecting the immune system2010

    • Author(s)
      Ishii T, Ishii M.
    • Journal Title

      Ann. Rheum. Dis

      Volume: 70 (Suppl 1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo2010

    • Author(s)
      Ishii M, Kikuta J, Shimazu Y, Meier-Schellersheim M, Germain RN
    • Journal Title

      J. Exp. Med

      Volume: 207 Pages: 2793-2798

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo.2010

    • Author(s)
      Ishii, et al.
    • Journal Title

      Journal of Experimental Medicine

      Volume: 207 Pages: 2793-2798

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] experiments and simulation to develop a physiological model of G-protein control of muscarinic K+ channels in mammalian atrial cells.2010

    • Author(s)
      Murakami S, Suzuki S, Ishii M, Inanobe A, Kurachi Y. Cellular modeling
    • Journal Title

      Phil Trans Roy Soc A. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079005
  • [Journal Article] Control of osteoclast precursor migration: A novel point of control for osteoclastogenesis and bone homeostasis2010

    • Author(s)
      Ishii T, Kikuta J, Kubo A, Ishii M
    • Journal Title

      IBMS BoneKey

      Volume: 7 Pages: 279-286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Journal Article] Quantifying cellular interaction dynamics in 3-D fluorescence microscopy data.2009

    • Author(s)
      Klauschen, Ishii, et al.
    • Journal Title

      Nature Protocols 4

      Pages: 1305-1311

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21113517
  • [Journal Article] Quantifying cellular interaction dynamics in 3-D fluorescence microscopy data.2009

    • Author(s)
      Klauschen, Ishii, et al.
    • Journal Title

      Nature Protocols 4

      Pages: 1305-1311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Journal Article] Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis.2009

    • Author(s)
      Ishii, et al.
    • Journal Title

      Nature 458

      Pages: 524-528

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21113517
  • [Journal Article] Quantifying cellular interaction dynamics in 3-D fluorescence microscopy data2009

    • Author(s)
      Klauschen F, Ishii M, Qi H, Bajenoff M, Egen JG, Germain RN, Meier-Schellersheim M
    • Journal Title

      Nature Protoc. 4(9)

      Pages: 1305-1311

    • Data Source
      KAKENHI-PROJECT-20790708
  • [Journal Article] Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis2009

    • Author(s)
      Ishii M, Egen JG, Klauschen F, Meier-Schellersheim M, Saeki Y, Vacher J, Praia RL, Germain RN
    • Journal Title

      Nature 458(7237)

      Pages: 524-528

    • Data Source
      KAKENHI-PROJECT-20790708
  • [Journal Article] Visualization and identification of IL-7 producing cells in reporter mice.2009

    • Author(s)
      Mazzucchelli, Ishii, et al.
    • Journal Title

      PLoS One 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21113517
  • [Journal Article] Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis2009

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Nature (published online)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Journal Article] Visualization and identification of IL-7 producing cells in reporter mice2009

    • Author(s)
      Mazzucchelli R. Warming S, Lawrence SM, Ishii M, Abshari M, Feigenbaum L, Washington AV, Warner AC, Sims DJ, Li WQ, Hixon JA, Gray DUD, Rich BE, Morrow M, Anver MR, Cherry J, Naf D, Sternberg LR, McVicar DW, Farr AG, Germain RN, Rogers K, Copeland N, Durum SK
    • Journal Title

      PLoS One 4(11)

    • Data Source
      KAKENHI-PROJECT-20790708
  • [Journal Article] Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis.2009

    • Author(s)
      Ishii, et al.
    • Journal Title

      Nature 458

      Pages: 524-528

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Journal Article] Visualization and identification of IL-7 producing cells in reporter mice.2009

    • Author(s)
      Mazzucchelli, Ishii, et al.
    • Journal Title

      PLoS One 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Journal Article] Osteoclastc ell fusion: Mechanisms and molecules2008

    • Author(s)
      Ishii M, Saeki Y.
    • Journal Title

      Mod Rheumatol. 18

      Pages: 220-227

    • NAID

      10024150622

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Journal Article] Muscarinic acetylcholine receptors.2006

    • Author(s)
      Ishii M et al.
    • Journal Title

      Current Pharmaceutical Design in press

    • Data Source
      KAKENHI-PROJECT-17790170
  • [Journal Article] RANKL-induced expression of tetraspanin CD9 in lipid raft membrane microdomain is essential for cell fusion during osteoclastogenesis.2006

    • Author(s)
      Ishii M, et al.
    • Journal Title

      The Journal of Bone & Mineral Research in press

    • Data Source
      KAKENHI-PROJECT-17790170
  • [Journal Article] Carvedilol blocks cardiac KATP and KG but not IK1 channels by acting at the bundle-crossing regions.2006

    • Author(s)
      Kikuta J, Ishii M, Kishimoto K, Kurachi Y.
    • Journal Title

      Eur J Pharmacol. Vol529

      Pages: 47-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079005
  • [Journal Article] Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins.2006

    • Author(s)
      Roof RA, Jin Y, Ishii M, et al.
    • Journal Title

      Chemical Biology & Drug Design in press

    • Data Source
      KAKENHI-PROJECT-17790170
  • [Journal Article] Muscarinic acetylcholine receptors.2006

    • Author(s)
      Ishii, M.
    • Journal Title

      Curr. Pharm. Des. 12巻・28号

      Pages: 3573-3581

    • Data Source
      KAKENHI-PROJECT-17079005
  • [Journal Article] Muscarinic acetylcholine receptors.2006

    • Author(s)
      Ishii M, Kurachi Y.
    • Journal Title

      Curr Pharm Des. Vol12

      Pages: 3573-3581

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079005
  • [Journal Article] Spot pattern of leopard Danio is caused by mutation in the zebrafish connexin41.8 gene.2006

    • Author(s)
      Watanabe M, Iwashita M, Ishii M, Kurachi Y, Kawakami A, Kondo A, Okada N.
    • Journal Title

      EMBO Rep. Vol7

      Pages: 893-897

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079005
  • [Journal Article] Phosphatidylinositol-3,4,5-trisphosphate and Ca^<2+>/calmodulin competitively bind to the RGS domain of RGS4 and reciprocally regulate its action.2005

    • Author(s)
      Ishii M, et al.
    • Journal Title

      The Biochemical Journal 385・1

      Pages: 65-73

    • Data Source
      KAKENHI-PROJECT-17790170
  • [Journal Article] In vivo interaction between RGS4 and calmodulin visualized with FRET techniques: possible involvement of lipid raft.2005

    • Author(s)
      Ishii M
    • Journal Title

      Biochem Biophys Res Commun 338(2)

      Pages: 839-846

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] Phosphatidylinositol 3,4,5-trisphosphate and Ca^<2+>/calmodulin competitively bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its action.2005

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Biochem J 385(1)

      Pages: 65-73

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] Phosphatidylinositol 3,4,5-trisphosphate and Cat^<2+>/calmodulin competitively bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its action.2005

    • Author(s)
      Ishii M
    • Journal Title

      Biochem J 385(1)

      Pages: 65-73

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] Phosphatidylinositol-3,4,5-trisphosphate and Ca^<2+>/calmodulin competitively bind to the RGS domain of RGS4 and reciprocally regulate its action.2005

    • Author(s)
      Ishii, M. et al.
    • Journal Title

      Biochemical Journal 385・1

      Pages: 65-73

    • Data Source
      KAKENHI-PROJECT-15790133
  • [Journal Article] Phosphatidylinositol 3, 4, 5-trisphosphate and Ca^<2+>/calmodulin competitively bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its action.2005

    • Author(s)
      Ishii M
    • Journal Title

      Biochem J 385(1)

      Pages: 65-73

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] In vivo interaction between RGS4 and calmodulin visualized with FRET techniques : possible involvement of lipid raft.2005

    • Author(s)
      Ishii, M.
    • Journal Title

      Biochem Biophys Res Commun. 338・2

      Pages: 839-846

    • Data Source
      KAKENHI-PROJECT-17079005
  • [Journal Article] In vivo interaction between RGS4 and calmodulin visualized with FRET techniques: possible involvement of lipid raft.2005

    • Author(s)
      Ishii M, Ikushima M, Kurachi Y.
    • Journal Title

      Biochem Biophys Res Commun. Vol338

      Pages: 839-846

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079005
  • [Journal Article] Phosphatidylinositol 3,4,5-trisphosphate and Ca^<2+>/calmodulin competitively bind to the regulators of G-protein-signaling (RGS) domain of RGS4 and reciprocally regulate its action.2005

    • Author(s)
      Ishii, M.et al.
    • Journal Title

      Biochemical Journal 385・Pt1

      Pages: 65-73

    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] In vivo interaction between RGS4 and calmodulin visualized with FRET techniques : possible involvement of lipid raft.2005

    • Author(s)
      Ishii, M.
    • Journal Title

      Biochem.Biophys.Res.Commun. 338・2

      Pages: 839-846

    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] Phosphatidylinositol 3, 4, 5-trisphosphate and Ca2+/calmodulin competitively bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its action.2005

    • Author(s)
      Ishii M, Fujita S, Yamada M, Hosaka Y, Kurachi Y.
    • Journal Title

      Biochem J. Vol385

      Pages: 65-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17079005
  • [Journal Article] Carvedilol blocks cardiac K_<ATP> and K_G but not l_<k1> channels by acting at the bundle crossing regions.2005

    • Author(s)
      Kikuta J, Ishii M, et al.
    • Journal Title

      European Journal of Pharmacology 529・1-3

      Pages: 47-54

    • Data Source
      KAKENHI-PROJECT-17790170
  • [Journal Article] Phosphatidylinositol 3,4,5-trisphosphate and Ca^<2+>/calmodulin competitively bind to the regulators of G-protein-signaling (RGS) domain of RGS4 and reciprocally regulate its action.2005

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Biochem J 385(1)

      Pages: 65-73

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] In vivo interaction between RGS4 and calmodulin visualized with FRET techniques : possible involvement of lipid raft.2005

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Biochem Biophys Res Commun 338(2)

      Pages: 839-846

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] Phosphatidylinositol-3,4,5-trisphosphate and Ca^<2+>/calmodulin competitively bind to the RGS domain of RGS4 and reciprocally regulate its action.2005

    • Author(s)
      Ishii, M. et al.
    • Journal Title

      Biochemical Journal 385・1

      Pages: 65-73

    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] In vivo interaction between RGS4 and calmodulin visualized with FRET techniques : Possible involvement of lipid raft.2005

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Biochemical & Biophysical Research Communications 338・2

      Pages: 839-846

    • Data Source
      KAKENHI-PROJECT-17790170
  • [Journal Article] In vivo interaction between RGS4 and calmodulin visualized with FRET techniques : possible involvement of lipid raft.2005

    • Author(s)
      Ishii M
    • Journal Title

      Biochem Biophys Res Commun 338(2)

      Pages: 839-846

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] Phosphatidylinositol 3,4,5-trisphosphate and Ca^<2+>/calmodulin competitive bind to the regulators of G-protein-signalling (RGS) domain of RGS4 and reciprocally regulate its action.2005

    • Author(s)
      Ishii, M.
    • Journal Title

      Biochem J. 385・1

      Pages: 65-73

    • Data Source
      KAKENHI-PROJECT-17079005
  • [Journal Article] Assays of RGS protein modulation by phosphatidylinositides and calmodulin.2004

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Methods Enzymol 389

      Pages: 105-118

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] Assays of RGS protein modulation by phosphatidylinositides and calmodulin.2004

    • Author(s)
      Ishii M
    • Journal Title

      Methods Enzymol 389

      Pages: 105-118

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] Mutation in nucleotide-binding domains of sulfonylurea receptor 2 evokes Na-ATP-dependent activation of ATP-sensitive K^+ Channels : Implication for dimerization of nucleotide-binding domains to induce channel opening.2004

    • Author(s)
      Yamada, M., Ishii, M.et al.
    • Journal Title

      Molecular Pharmacology 66・4

      Pages: 807-816

    • Data Source
      KAKENHI-PROJECT-15790133
  • [Journal Article] Cell signal control of the G protein-gated potassium channel and its subcellular localization.2004

    • Author(s)
      Kurachi, Y, Ishii, M.
    • Journal Title

      The Journal of Physiology 554・2

      Pages: 285-294

    • Data Source
      KAKENHI-PROJECT-15790133
  • [Journal Article] Assays of RGS protein modulation by phosphatidylinositides and calmodulin.2004

    • Author(s)
      Ishii, M., Kurachi, Y.
    • Journal Title

      Method Enzymology 389

      Pages: 105-118

    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] Cell signal control of the G protein-gated potassium channel and its subcellular localization.2004

    • Author(s)
      Kurachi, Y., Ishii, M.
    • Journal Title

      The Journal of Physiology 554・2

      Pages: 285-294

    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] Assay of RGS protein modulation by phosphatidylinositides and calmodulin.2004

    • Author(s)
      Ishii, M., Kurachi, Y.
    • Journal Title

      Methods in Enzymology 389

      Pages: 105-118

    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] Mutation in nucleotide-binding domains of sulfonylurea receptor 2 evokes Na-AIP-dependent activation of ATP-Sensitive K^+ Channels : Implication for dimerization of nucleotide-binding domains to induce channel opening.2004

    • Author(s)
      Yamada, M., Ishii, M.et al.
    • Journal Title

      Molecular Pharmacology 66・4

      Pages: 807-816

    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] Assay of RGS protein modulation by phosphatidylinositides and calmodulin.2004

    • Author(s)
      Ishii, M., Kurachi, Y.
    • Journal Title

      Methods in Enzymology 389

      Pages: 105-118

    • Data Source
      KAKENHI-PROJECT-15790133
  • [Journal Article] Physiological actions of regulators of G-protein signaling (RGS) proteins.2003

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Life Sci 74(2-3)

      Pages: 163-171

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] Physiological actions of regulators of G-protein signaling (RGS) proteins2003

    • Author(s)
      Ishii M
    • Journal Title

      Life Sci 74(2-3)

      Pages: 163-171

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K^+ channels in retina.2003

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Am J Physiol Cell Physiol 285(2)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] Differential expression and distribution of Kir5.1 and Kir4.1 inwardly rectifying K^+ channels in retina.2003

    • Author(s)
      Ishii M
    • Journal Title

      Am J Physiol Cell Physiol 285(2)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209008
  • [Journal Article] Physiological actions of regulators of G-protein signaling (RGS) proteins.2003

    • Author(s)
      Ishii, M., Kurachi, Y.
    • Journal Title

      Life Sciences 74・2-3

      Pages: 163-171

    • Data Source
      KAKENHI-PROJECT-15790133
  • [Journal Article] The 14-3-3 protein as a novel regulator of ion channel localisation.2002

    • Author(s)
      Ishii M, et al.
    • Journal Title

      J Physiol 545(1)

      Pages: 2-2

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] PIP_3 inhibition of RGS protein and its reversal by Ca^<2+>/calmodulin mediate voltage-dependent control of the G protein cycle in a cardiac K^+ channel.2002

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Proc Natl Acad Sci USA 99(7)

      Pages: 4325-4330

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] The 14-3-3 protein as a novel regulator of ion channel localisation.2002

    • Author(s)
      Ishii M, et al.
    • Journal Title

      JPhysiol 545(1)

      Pages: 2-2

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] Ca^<2+> elevation evoked by membrane depolarization regulates G protein cycle via RGS proteins in the heart.2001

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Circ Res 89(11)

      Pages: 1045-1050

    • NAID

      110002636883

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Journal Article] G Protein and Effectors.

    • Author(s)
      Ishii M, et al.
    • Journal Title

      Encyclopedia of Endocrinology and Endocrine Diseases 2004.

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144207
  • [Patent] 関節炎治療剤2018

    • Inventor(s)
      長谷川哲雄、菊田順一、石井優
    • Industrial Property Rights Holder
      大阪大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-207209
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16H02619
  • [Patent] 評価方法、評価装置およびプログラム2018

    • Inventor(s)
      石井優、菊田順一、松田秀雄、瀬尾茂人
    • Industrial Property Rights Holder
      石井優、菊田順一、松田秀雄、瀬尾茂人
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-007571
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K12525
  • [Patent] 新規抗腫瘍剤及びそのスクリーニング方法2012

    • Inventor(s)
      石井優, 他
    • Industrial Property Rights Holder
      国立大学法人大阪大学
    • Industrial Property Number
      2012-015982
    • Filing Date
      2012-01-30
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Patent] 新規抗腫瘍剤及びそのスクリーニング方法2012

    • Inventor(s)
      石井 優,賀川義規,森 正樹,石井秀始
    • Industrial Property Rights Holder
      国立大学法人大阪大学
    • Industrial Property Number
      2012-015982
    • Filing Date
      2012-01-30
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Patent] 新規抗腫瘍剤及びそのスクリーニング方法2012

    • Inventor(s)
      石井優, 他
    • Industrial Property Rights Holder
      国立大学法人大阪大学
    • Industrial Property Number
      2012-015982
    • Filing Date
      2012-01-30
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Patent] 画像処理装置および方法、並びにプログラム2011

    • Inventor(s)
      石井 優,菊田順一,米谷信男
    • Industrial Property Rights Holder
      国立大学法人大阪大学・ニコン株式会社
    • Industrial Property Number
      2011-232479
    • Filing Date
      2011-10-24
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Patent] 新規骨吸収抑制剤のスクリーニング方法2010

    • Inventor(s)
      石井優
    • Industrial Property Rights Holder
      国立大学法人大阪大学
    • Filing Date
      2010-11-10
    • Overseas
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Patent] 新規骨吸収抑制剤のスクリーニング方法2010

    • Inventor(s)
      石井優
    • Industrial Property Rights Holder
      国立大学法人大阪大学
    • Filing Date
      2010-11-10
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Patent] 脂質メディエーターやケモカインを標的とした骨吸収性疾患に対する新規治療法2009

    • Inventor(s)
      石井優
    • Industrial Property Rights Holder
      大阪大学
    • Industrial Property Number
      2009-260655
    • Filing Date
      2009-11-16
    • Data Source
      KAKENHI-PUBLICLY-21113517
  • [Patent] 新規骨吸収抑制剤のスクリーニング方法2009

    • Inventor(s)
      石井優
    • Industrial Property Rights Holder
      国立大学法人大阪大学
    • Industrial Property Number
      2009-260655
    • Filing Date
      2009-11-16
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Patent] 新規骨吸収抑制剤のスクリーニング方法2009

    • Inventor(s)
      石井 優
    • Industrial Property Rights Holder
      国立大学法人大阪大学
    • Industrial Property Number
      2009-260655
    • Filing Date
      2009-11-16
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Patent] 脂質メディエーターやケモカインを標的とした骨吸収性疾患に対する新規治療法2009

    • Inventor(s)
      石井優
    • Industrial Property Rights Holder
      大阪大学
    • Industrial Property Number
      2009-260655
    • Filing Date
      2009-11-16
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] Novel imaging-based methods for validating immunopharmacology on rheumatic diseases2023

    • Author(s)
      Masaru Ishii
    • Organizer
      19th World Congress of basic and clinical pharmacology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-20H05901
  • [Presentation] Novel imaging-based methods for validating immunopharmacology on rheumatic diseases2023

    • Author(s)
      Masaru Ishii
    • Organizer
      19th World Congress of basic and clinical pharmacology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05657
  • [Presentation] Intravital Imaging-Based Single Cell Transcriptomics Identifies a Novel Macrophage Subset in the Liver2023

    • Author(s)
      Masaru Ishii
    • Organizer
      The second international school on advanced immunology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-20H05901
  • [Presentation] Intravital Imaging-Based Single Cell Transcriptomics Identifies a Novel Macrophage Subset in the Liver2023

    • Author(s)
      Masaru Ishii
    • Organizer
      The second international school on advanced immunology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05657
  • [Presentation] Arthritic osteoclastogenic macrophages2022

    • Author(s)
      Masaru Ishii
    • Organizer
      Annual Meeting of the American College of Rheumatology 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-20H05901
  • [Presentation] Intravital imaging dissecting pathogenic macrophages in vivo2022

    • Author(s)
      Masaru Ishii
    • Organizer
      Cambridge Immunology Seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-20H05901
  • [Presentation] Intravital imaging dissecting pathogenic macrophages in vivo2022

    • Author(s)
      Masaru Ishii
    • Organizer
      Cambridge Immunology Seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05657
  • [Presentation] Intravital Imaging of live bone cells in vivo2022

    • Author(s)
      Masaru Ishii
    • Organizer
      The 49th International Musculoskeletal Biology Workshop
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-20H05901
  • [Presentation] Arthritic osteoclastogenic macrophages2022

    • Author(s)
      Masaru Ishii
    • Organizer
      Annual Meeting of the American College of Rheumatology 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05657
  • [Presentation] Intravital Imaging of live bone cells in vivo2022

    • Author(s)
      Masaru Ishii
    • Organizer
      The 49th International Musculoskeletal Biology Workshop
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05657
  • [Presentation] Function of ILC2 in bone marrow2022

    • Author(s)
      Masaru Ishii
    • Organizer
      VIB-conference on Type 2 Immunity in Homeostasis and Disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05657
  • [Presentation] Function of ILC2 in bone marrow2022

    • Author(s)
      Masaru Ishii
    • Organizer
      VIB-conference on Type 2 Immunity in Homeostasis and Disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-20H05901
  • [Presentation] 蛍光生体イメージングで解く免疫・骨における細胞動態ネットワークの世界2021

    • Author(s)
      石井 優
    • Organizer
      第20回日本再生医療学会総会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-20H05894
  • [Presentation] リウマチ炎症・骨破壊の実体の解明~TNF 阻害剤などのバイオ製剤の新たな可能性~2021

    • Author(s)
      石井 優
    • Organizer
      第61回九州リウマチ学会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-20H05894
  • [Presentation] Dynamics of immune cell migration and interaction visualized by intravital microscopy.2021

    • Author(s)
      Masaru Ishii
    • Organizer
      Annual Congress of European Calcified Tissue Society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05657
  • [Presentation] 生命動態イメージング技術による免疫・炎症ダイナミクスの解明:日本発の“免疫薬理学”の創出に向けて2019

    • Author(s)
      石井 優
    • Organizer
      第92回日本薬理学会年会・第12回江橋節郎賞受賞記念講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H02619
  • [Presentation] Dynamics of immune cell migration and interaction visualized by intravital microscopy.2019

    • Author(s)
      Masaru Ishii
    • Organizer
      14th World Congress of Inflammation
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05657
  • [Presentation] Intravital imaging dissecting immune cell dynamics and modes of pharmacological actions in vivo2018

    • Author(s)
      Masaru Ishii
    • Organizer
      WCP2018 Frontier Session
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02619
  • [Presentation] 細胞個体の移動傾向の違いを考慮したグローバルデータアソシエーションを用いた細胞追跡手法2017

    • Author(s)
      伊藤澄美, 瀬尾茂人, 繁田浩功, 菊田順一, 竹中要一, 石井優, 松田秀雄
    • Organizer
      情報処理学会 第112回数理モデル化と問題解決研究発表会
    • Place of Presentation
      清温荘 (岩手県)
    • Year and Date
      2017-02-27
    • Data Source
      KAKENHI-PROJECT-16K12525
  • [Presentation] Lipid mediators controlling dynamics of immune and bone cells2017

    • Author(s)
      Masaru Ishii
    • Organizer
      Pharmacology 2017 (British Pharmacological Society Meeting)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02619
  • [Presentation] Sphingosine 1-phosphate controlling bone remodeling and inflammatio2017

    • Author(s)
      Masaru Ishii
    • Organizer
      FASEB Science Research Conferences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02619
  • [Presentation] A method of bioimage analysis for spatial pattern of cellular interaction and intercalation2017

    • Author(s)
      Shigeto Seno, Masayuki Furuya, Junichi Kikuta, Masaru Ishii, Hideo Matsuda
    • Organizer
      International Conference on Intelligent Systems for Molecular Biology and European Conference on Computational Biology (ISMB/ECCB 2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K12525
  • [Presentation] Analyzing cell migration dynamics from intravital imaging by deformable image matching2017

    • Author(s)
      Hideo Matsuda, Hironori Shigeta, Shigeto Seno, Junichi Kikuta, Masaru Ishii
    • Organizer
      International Conference on Intelligent Systems for Molecular Biology and European Conference on Computational Biology (ISMB/ECCB 2017)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K12525
  • [Presentation] In vivo bone imaging: opening a new era in the field of bone and mineral research2017

    • Author(s)
      Masaru Ishii
    • Organizer
      Australia New Zealand Bone Mineral Society Meeting (ANZBMS)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02619
  • [Presentation] A bone marrow cavity segmentation method using wavelet-based texture feature2016

    • Author(s)
      Hironori Shigeta, Tomohiro Mashita, Junichi Kikuta, Shigeto Seno, Haruo Takemura, Hideo Matsuda, Masaru Ishii
    • Organizer
      International Conference on Pattern Recognition (ICPR2016)
    • Place of Presentation
      Cancun Center, Cancun, Mexico
    • Year and Date
      2016-12-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K12525
  • [Presentation] ウェーブレット特徴量を用いた生体骨組織の骨髄腔の領域分割手法2016

    • Author(s)
      繁田浩功, 間下以大, 菊田順一, 瀬尾茂人, 竹村治雄, 松田秀雄, 石井優
    • Organizer
      バイオイメージ・インフォマティクスワークショップ 2016
    • Place of Presentation
      大阪大学銀杏会館(大阪府)
    • Year and Date
      2016-06-22
    • Data Source
      KAKENHI-PROJECT-16K12525
  • [Presentation] Intravital imaging of bone cell dynamics2016

    • Author(s)
      Ishii M
    • Organizer
      European Calcified Tissue Society
    • Place of Presentation
      Rome (Italy)
    • Year and Date
      2016-05-15
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H02619
  • [Presentation] 模様特徴量とグラフカットを利用した生体骨組織の骨髄腔の領域分割2016

    • Author(s)
      繁田浩功,間下以大,菊田順一,瀬尾茂人,石井優,松田秀雄
    • Organizer
      第5回生命医薬情報学連合大会
    • Place of Presentation
      東京国際交流館プラザ平成(東京都)
    • Year and Date
      2016-09-29
    • Data Source
      KAKENHI-PROJECT-16K12525
  • [Presentation] オプティカルフローとウェーブレット解析を用いた白血球の動態の解析手法2016

    • Author(s)
      松原周平, 瀬尾茂人, 西澤志乃, 菊田順一, 竹中要一, 石井優, 松田秀雄
    • Organizer
      バイオイメージ・インフォマティクスワークショップ 2016
    • Place of Presentation
      大阪大学銀杏会館(大阪府)
    • Year and Date
      2016-06-22
    • Data Source
      KAKENHI-PROJECT-16K12525
  • [Presentation] S1P-mediated control of bone cell dynamics visualized by intra-vital microscopy2014

    • Author(s)
      Masaru Ishii
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Ventura, CA (USA)
    • Invited
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Presentation] S1P-mediated control of bone cell dynamics visualized by intra-vital microscopy2014

    • Author(s)
      Masaru Ishii
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      Ventura, CA (USA)
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253070
  • [Presentation] Effect of sphingosine 1 phosphate on osteoclast differentiation2014

    • Author(s)
      Amano H, Ryu K, Iwai S, Kikuta J, Ishii M, Oguchi K.
    • Organizer
      The 87th Annual Meeting of The Japanese Pharmacological Society
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25462899
  • [Presentation] Intravital multiphoton imaging dissecting cellular dynamics in live animals.2013

    • Author(s)
      Masaru Ishii
    • Organizer
      Cold Spring Harbor Conference Asia
    • Place of Presentation
      Suzhou (China)
    • Invited
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Presentation] 経時観測蛍光画像からのモーションヒストリーイメージを用いた細胞分裂の検出方法2013

    • Author(s)
      福田浩二郎, 瀬尾茂人, 間下以大, 前田栄, 竹中要一, 石井優, 松田秀雄
    • Organizer
      画像の認識・理解シンポジウムMIRU2013
    • Place of Presentation
      国立情報学研究所, 東京
    • Data Source
      KAKENHI-PROJECT-24651229
  • [Presentation] Global Data Associationによる経時観察画像における破骨前駆細胞の自動追跡手法2013

    • Author(s)
      尾野貴広, 瀬尾茂人, 間下以大, 竹中要一, 石井優, 松田秀雄
    • Organizer
      画像の認識・理解シンポジウムMIRU2013
    • Place of Presentation
      国立情報学研究所, 東京
    • Data Source
      KAKENHI-PROJECT-24651229
  • [Presentation] Intravital multiphoton imaging dissecting cellular dynamics in live animals.2013

    • Author(s)
      Masaru Ishii
    • Organizer
      Cold Spring Harbor Conference Asia
    • Place of Presentation
      Suzhou (China)
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253070
  • [Presentation] Roles of S1P in osteoclast regulation and bone physiology2012

    • Author(s)
      Ishii M
    • Organizer
      2012 Gordon Research Conference
    • Place of Presentation
      Il Ciocco, Italy
    • Year and Date
      2012-04-24
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Presentation] Dynamic behaviors of osteoclast function visualized by intravital imaging2012

    • Author(s)
      Masaru Ishii
    • Organizer
      Cold Spring Harbor Asia Conference
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2012-06-11
    • Invited
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Presentation] Dynamic behaviors of osteoclast function visualized by intravital imaging2012

    • Author(s)
      Masaru Ishii
    • Organizer
      Cold Spring Harbor Asia Conference
    • Place of Presentation
      Suzhou, China
    • Invited
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Presentation] Roles of S1P in osteoclast regulation and bone physiology.2012

    • Author(s)
      Masaru Ishii
    • Organizer
      2012 Gordon Research Conference
    • Place of Presentation
      Il Ciocco, Italy
    • Year and Date
      2012-04-22
    • Invited
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Presentation] Roles of S1P in osteoclast regulation and bone physiology.2012

    • Author(s)
      Masaru Ishii
    • Organizer
      2012 Gordon Research Conference
    • Place of Presentation
      Il Ciocco, Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Presentation] Roles of S1P in osteoclast regulation and bone remodeling2011

    • Author(s)
      Ishii M
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Il Ciocco, Italy
    • Year and Date
      2011-08-18
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Presentation] Roles of S1P in osteoclast regulation and bone remodeling2011

    • Author(s)
      Masaru Ishii
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Il Ciocco, Italy(招待講演)
    • Year and Date
      2011-08-18
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Presentation] Roles of S1P in osteoclast regulation and bone remodeling2011

    • Author(s)
      Masaru Ishii
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      II Ciocco, Italy(招待講演)
    • Year and Date
      2011-08-18
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Presentation] Chemokine-mediated migration control of osteoclast precursors visualized by intravital bone imaging: A novel point of regulation for bone homeostasis2010

    • Author(s)
      Masaru Ishii
    • Organizer
      The 14th International Conferences on Endocrinology 2010(ICE2010)
    • Place of Presentation
      京都
    • Year and Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] Chemokine-mediated migration control of osteoclast precursors visualized by dynamic in vivo bone imaging: A novel point of regulation for bone homeostasis2010

    • Author(s)
      石井優
    • Organizer
      第83日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] Chemokine and lipid mediator-mediated control of osteoclast migration visualized by in vivo bone imaging : A novel point of regulation for bone homeostasis.2010

    • Author(s)
      Masaru Ishii
    • Organizer
      International Bone and Mineral Society
    • Place of Presentation
      Davos (Switzerland)
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] Chemokine and lipid mediator-mediated control of osteoclast migration visualized by in vivo bone imaging: A novel point of regulation for bone homeostasis2010

    • Author(s)
      Masaru Ishii
    • Organizer
      International Bone and Mineral Society (IBMS)
    • Year and Date
      2010-03-14
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] Chemokine and lipid mediator-mediated control of osteoclast migration visualized by in vivo bone imaging : A novel point of regulation for bone homeostasis.2010

    • Author(s)
      Masaru Ishii
    • Organizer
      International Bone and Mineral Society
    • Place of Presentation
      Davos (Switzerland)
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PUBLICLY-21113517
  • [Presentation] Chemokine-mediated migration control of osteoclast precursors visualized by live bone imaging2010

    • Author(s)
      Ishii M
    • Organizer
      3rd International Conference of Osteoimmunology
    • Place of Presentation
      Santorini, Greece
    • Year and Date
      2010-06-21
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Presentation] Chemokine-mediated migration control of osteoclast precursors visualized by live bone imaging2010

    • Author(s)
      Masaru Ishii
    • Organizer
      3rd International Conference of Osteoimmunology
    • Place of Presentation
      Santorini/Greece(招待講演)
    • Year and Date
      2010-06-21
    • Data Source
      KAKENHI-PROJECT-22689030
  • [Presentation] Chemokine-mediated migration control of osteoclast precursors visualized by live bone imaging2010

    • Author(s)
      Masaru Ishii
    • Organizer
      3rd International Conference of Osteoimmunology
    • Place of Presentation
      Santorini/Greece(招待講演)
    • Year and Date
      2010-06-21
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Presentation] Dynamics of osteoclast precursor migration visualized by in vivo bone imaging: A novel point of control for bone homeostasis2010

    • Author(s)
      Masaru Ishii
    • Organizer
      The 14th International Conferences on Endocrinology 2010(ICE2010)
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-31
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] SIP-mediated migration control of osteoclast precursors visualized by in vivo bone imaging: A novel point of regulation for bone metabolism2009

    • Author(s)
      Masaru Ishii
    • Organizer
      PLM2009(国際学会)
    • Place of Presentation
      東京
    • Year and Date
      2009-05-27
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] Chemokine-mediated migration control of osteoclast precursors visualized by in vivo bone imaging: A novel point of regulation for osteoimmunology2009

    • Author(s)
      Masaru Ishii
    • Organizer
      第2回・IFReC国際シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2009-02-11
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] Dynamics of osteoclast precursor migration visualized by in viva bone imaging: A novel point of control for osteoimmunoIogy2009

    • Author(s)
      Masaru Ishii
    • Organizer
      第3回・GCOE国際シンポジウム
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2009-06-11
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] ~見てみて分かった破骨細胞の遊走と位置決めの制御機構~骨組織の生体二光子励起顕微鏡イメージングより2009

    • Author(s)
      石井優
    • Organizer
      免疫サマースクール2009
    • Place of Presentation
      淡路
    • Year and Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] Dynamic in vivo visualizahon of osteoclast precursor migration in living bones elucidating a novel regulatory point for 'osteoimmunologY'2009

    • Author(s)
      石井優
    • Organizer
      第39日本免疫学会大会
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] 二光子励起顕微鏡を駆使した骨組織内のインビボ光イメージング~破骨細胞分化・骨吸収の新しい調節作用点の発見~2009

    • Author(s)
      石井優
    • Organizer
      第31日本分子生物学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] スフィンゴシン1リン酸による破骨前駆細胞の遊走・位置決めの制御機構~生体多光子励起顕微鏡を用いた骨組織内のin vivoイメージングより~2009

    • Author(s)
      石井優
    • Organizer
      第82回・日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] 骨組織のライブイメージング~その方法論と今後の応用~2009

    • Author(s)
      石井優
    • Organizer
      第27回・日本骨代謝学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-24
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] 脂質メディエーターやケモカインによる破骨細胞前駆細胞の遊走・位置決めの制御〜生体多光子励起顕微鏡を用いた骨組織のin vivoイメージングより〜2008

    • Author(s)
      石井優
    • Organizer
      日本生化学・分子生物学合同大会・シンポジウム
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] Chemokine-mediated migration control of osteoclast precursors visualized by in vivo bone imaging: A novel point of control for bone homeostasis2008

    • Author(s)
      Masaru Ishii
    • Organizer
      6th Bone Biology Forum
    • Place of Presentation
      静岡県裾野市
    • Year and Date
      2008-08-21
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] 脂質メディエーターやケモカインによる破骨細胞前駆細胞の遊走・位置決めの制御~生体多光子励起顕微鏡を用いた骨組織のin vivOイメージングより~2008

    • Author(s)
      石井優
    • Organizer
      BMB2008(生化学・分子生物学会合同大会)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20790708
  • [Presentation] Intravital multiphoton imaging revealing immune cell dynamics in bone destruction in vivo.

    • Author(s)
      Masaru Ishii
    • Organizer
      CSHA Conference on Bone and Cartilage: from Development to Human Diseases
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2014-11-04 – 2014-11-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253070
  • [Presentation] Intravital multiphoton imaging revealing immune cell dynamics in inflammation and bone destruction in vivo.

    • Author(s)
      Masaru Ishii
    • Organizer
      Japan-Germany Cancer Workshop
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2014-11-14 – 2014-11-15
    • Invited
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Presentation] Improvement approach of cell tracking accuracy by using inter-frame information

    • Author(s)
      Kohei Kurashige, Shigeto Seno, Tomohiro Mashita, Junichi Kikuta, Yoichi Takenaka, Masaru Ishii, Hideo Matsuda
    • Organizer
      Bioimage Informatics Conference
    • Place of Presentation
      フラームスブラバント州庁舎(ルーベン、ベルギー)
    • Year and Date
      2014-10-08 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-24651229
  • [Presentation] An automatic event detection method using semi-supervised learning for time-lapse imaging data

    • Author(s)
      Kojiro Fukuda, Shigeto Seno, Tomohiro Mashita, Yoichi Takenaka, Masaru Ishii, Hideo Matsuda
    • Organizer
      Bioimage Informatics Conference
    • Place of Presentation
      フラームスブラバント州庁舎(ルーベン、ベルギー)
    • Year and Date
      2014-10-08 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-24651229
  • [Presentation] Intravital multiphoton imaging revealing immune cell dynamics in bone destruction in vivo.

    • Author(s)
      Masaru Ishii
    • Organizer
      CSHA Conference on Bone and Cartilage: from Development to Human Diseases
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2014-11-04 – 2014-11-07
    • Invited
    • Data Source
      KAKENHI-PLANNED-22113007
  • [Presentation] Intravital multiphoton imaging revealing immune cell dynamics in inflammation and bone destruction in vivo.

    • Author(s)
      Masaru Ishii
    • Organizer
      Japan-Germany Cancer Workshop
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2015-11-15 – 2015-11-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-25253070
  • 1.  INANOBE Atsushi (00270851)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 2.  KURACHI Yoshihisa (30142011)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 3.  MICHIYUKI Matsuda (10199812)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  MATSUDA Hideo (50183950)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 5.  SENO Shigeto (30432462)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 15 results
  • 6.  TANEMOTO Masayuki (40303945)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  HIBINO Hiroshi (70314317)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  MURAKAMI Shingo (40437314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  FURUTANI Kazuharu (40452437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  IMAMURA Takeshi (70264421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KIYOKAWA Etsuko (80300929)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MIYAWAKI Atsushi (80251445)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NEMOTO Tomomi (50291084)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  OKADA Takaharu (50452272)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  FUKUHARA Shigetomo (70332880)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SUZUKI Keiko (50119187)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YAMADA Shoji (00111617)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TANIMURA Akihiko (70217149)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  FUJITA Akikazu (60282232)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MORISHIGE Ken-ichiro (90283788)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  MARUYAMA Yoshio (00133942)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  AMANO Hitoshi (90212571)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  山田 充彦 (10263237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 24.  中野 泰子 (20155790)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 25.  岩井 信市 (70317519)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 26.  蛯名 耕介 (70612076)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  岡部 繁男 (60204012)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  星野 歩子 (00819964)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  小泉 修一 (10280752)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  田中 謙二 (30329700)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  津田 誠 (40373394)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 32.  史 蕭逸 (40803656)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 33.  小山 隆太 (90431890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  和氣 弘明 (90455220)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  竹田 潔 (20309446)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  黒崎 知博 (50178125)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  坂口 志文 (30280770)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  茂呂 和世 (90468489)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  IKEDA Junichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  小池 正人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  奥崎 大介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  菊田 順一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 43.  清水 俊一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  根来 孝治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  森本 彬人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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