Yamaguchi Yoko 山口陽子

… Alternative Names

YAMAGUCHI Yoko 山口陽子

FUJITA Yoko 山口陽子

Less

Researcher Number	10328106
Other IDs
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 客員教授
Affiliation (based on the past Project Information) *help	2025: 順天堂大学, 大学院医学研究科, 客員教授 2010 – 2012: 東海大学, 工学部, 教授 2005 – 2007: 東海大学, 工学部, 教授
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Functional biochemistry / Structural biochemistry
Keywords	Principal Investigator downregulation / 単鎖抗体 / Anti-tumor erowth / cancer molecular thera / single chain antibody / Anti-IGF-I receptor / Phage display法 / ヒト単鎖抗体 / 抗IGF-I 受容体 / 抗がん効果 … More / ダウンレギュレーション / がん分子標的治療法 / 抗IGF-I受容体 / 昆虫細胞発現系 / 糖鎖親和性 / 糖鎖結合性 / リフォールディング / 封入体 / 大腸菌発現系 Less

SHAレクチン結合性糖鎖から紐解く膵がん発症機構の解明と早期診断への応用Principal Investigator
- Principal Investigator
  
  山口陽子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Juntendo University
Expression of novel carbohydrate-specific single chain antibodies in E. coli and analyses of carbohydrate-binding activities of purified antibodiesPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Yoko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tokai University
Insulin-like growth factor-I receptor-targeted cancer therapyPrincipal Investigator
- Principal Investigator
  
  FUJITA Yoko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokai University

All 2012 2011 2010 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] Construction and expression of anti-Tn-antigen-specific single chain antibody genes from hybridoma producing MLS128 monoclonal antibody2012
- Author(s)
  Yuasa, N., Ogawa, H., Koizumi, T., Tsukamoto, K., Matsumoto-Takasaki, A., Asanuma, H., Nakada, H., Fujita-Yamaguchi, Y.
- Journal Title
  
  J Biochem.151. Feb 8
  
  Volume: 151(Epub ahead of print)(Not known yet)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Surface plasmon resonance and NMR analyses of anti Tn-antigen MLS128 monoclonal antibody binding to two or three consecutive Tn-antigen cluster2012
- Author(s)
  Matsumoto-Takasaki, A., Hanashima, S., Aoki, A., Yuasa, N., Ogawa, H., Sato, R., Kawakami, H., Mizuno, M., Nakada, H., Yamaguchi, Y., Fujita-Yamaguchi, Y.
- Journal Title
  
  J Biochem.151
  
  Volume: 151 Pages: 273-282
- NAID
  10031166066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Construction and expression of anti-Tn-antigen-specific single chain antibody genes from hybridoma producing MLS128 monoclonal antibody2012
- Author(s)
  Yuasa, N., Ogawa, H., Koizumi, T., Tsukamoto, K., Matsumoto-Takasaki, A., Asanuma, H., Nakada, H., and Fujita- Yamaguchi, Y.
- Journal Title
  
  J Biochem
  
  Volume: 151 Pages: 371-381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Surface plasmon resonance and NMR analyses of anti Tn-antigen MLS128 monoclonal antibody binding to two or three consecutive Tn-antigen cluster2012
- Author(s)
  Matsumoto-Takasaki, A., Hanashima, S.. Aoki, A., Yuasa, N., Ogawa, H., Sato, R., Kawakami, H., Mizuno, M. Nakada, H.,Yamaguchi, Y., and Fujita-Yamaguchi, Y
- Journal Title
  
  J Biochem.
  
  Volume: 151 Pages: 273-282
- NAID
  10031166066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Overproduction of anti-Tn antibody MLS128 single-chain Fv fragment in Escherichia coli cytoplasm using a novel pCold-PDI vector2012
- Author(s)
  Subedi, G.P., Satoh, T., Hanashima, S., Ikeda, A., Nakada, H., Sato, R., Mizuno M., Yuasa, N., Fujita-Yamaguchi Y., Yamaguchi, Y.
- Journal Title
  
  Protein Expr.Puri.
  
  Volume: 82 Pages: 197-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Overproduction of anti-Tn antibody MLS128 single-chain Fv fragment in Escherichia coli cytoplasm using a novel pCold-PDI vector2012
- Author(s)
  Subedi, G.P., Satoh, T., Hanashima,S., Ikeda, A., Nakada, H., Sato, R., Mizuno M., Yuasa, N., Fujita-Yamaguchi, Y., and Yamaguchi, Y.
- Journal Title
  
  Protein Expr. Puri
  
  Volume: 82 Pages: 197-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Effects of two monoclonal antibodies, MLS128 against Tn-antigen and 1H7 against insulin-like growth factor-I receptor, on the growth of colon cancer cells2012
- Author(s)
  Zamri, N., Masuda, N., Oura, F., Yajima, Y., Nakada, H., and Fujita-Yamaguchi, Y
- Journal Title
  
  Biosci Trends
  
  Volume: 6 Pages: 303-312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] がん診断薬・抗体療法向け創薬を目指した糖鎖特異的ヒト型抗体の開発2011
- Author(s)
  山口(藤田)陽子、高崎(松本)綾乃、酒井恵子、湯浅徳行
- Journal Title
  
  Journal of the Society of Japanese Women Scientists
  
  Volume: 11 Pages: 19-28
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Characterization of three different single chain antibodies recognizing non reducing terminal mannose residues expressed in Escherichia coli by an inducible T7 expression system2011
- Author(s)
  Matsumoto-Takasaki, A., Yuasa, N., Katagiri, D., Koyama, T., Sakai, K., Zamri, N., Phung, S., Chen, S., Nakada, H., Nakata, M., Fujita-Yamaguchi, Y.
- Journal Title
  
  J Biochem.150
  
  Volume: 150 Pages: 439-450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Characterization of three different single chain antibodies recognizing nonreducing terminal mannose residues expressed in Escherichia coli by an inducible T7 expression system2011
- Author(s)
  Matsumoto-Takasaki, A., Yuasa, N., Katagiri, D., Koyama, T., Sakai, K., Zamri, N., Phung, S., Chen, S., Nakada, H., Nakata, M., Fujita-Yamaguchi, Y.
- Journal Title
  
  J Biochem
  
  Volume: 150 Pages: 439-450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Preparation of asialo-agalacto-glycophorin A for screening of and-Tn antibodies.2010
- Author(s)
  Koizumi, T., Matsumoto-Takasaki, A., Nakada, H., Nakata, M., Fujita-Yamaguchi, Y.
- Journal Title
  
  Bioscience Trends
  
  Volume: 4 Pages: 308-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Preparation of asialo-agalacto- glycophorin A for screening of anti-Tn antibodies2010
- Author(s)
  Koizumi, T., Matsumoto-Takasaki, A., Nakada, H., Nakata, M., Fujita-Yamaguchi, Y.
- Journal Title
  
  BioScience Trends
  
  Volume: 4 Pages: 308-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Production of anti-carbohydrate antibodies by phage-display technologies: Potential impairment of cell growth as a result of endogenous expression2010
- Author(s)
  Yuasa, N., Zhang, W., Goto, T., Sakaue, H., Matsumoto- Takasaki, A., Kimura, M., Ohshima, H., Tsuchida, Y., Koizumi, T., Sakai, K., Kojima, T., Yamamoto, K., Nakata, M., and Fujita-Yamaguchi, Y.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 30587-30597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Production of anti-carbohydrate antibodies by phage-display technologies : Potential impairment of cell growth as a result of endogenous expression.2010
- Author(s)
  Yuasa, N., Zhang, W., Goto, T., Sakaue, H., Matsumoto- Takasaki, A., Kimura, M., Ohshima, H., Tsuchida, Y., Koizumi, T., Sakai, K., Kojima, T., Yamamoto, K., Nakata, M., Fujita-Yamaguchi, Y.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 30587-30597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570125
[Journal Article] Construction and characterization of single-chain antibodies against human insulin-like growth factor-1 Receptor from hybridomas producing 1H7 and 3B7 monoclonal antibody2008
- Author(s)
  Kusada, Y, Morizono, T., Matsumoto-Takasaki, A., Sakai, K., Sato, S., Asanuma, H., Takayanagi, A., and Fujita-Yamaguchi, Y.
- Journal Title
  
  J.Biochem. 143
  
  Pages: 9-19
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17570120
[Journal Article] Construction and characterization of single-chain antibodies against human insulin-like growth factor-1 Receptor from hybridomas producing 1H7 and 3B7 monoclonal antibody2008
- Author(s)
  Kusada, Y, Morizono, T., Matsumoto-Takasaki, A., Sakai, K., Sato, S., Asanuma, H., Takayanagi, A., Fujita-Yamaguchi, Y
- Journal Title
  
  J. Biochem 143
  
  Pages: 9-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Journal Article] An overview of currently available anti-insulin-like growth factor I receptor antibodies2007
- Author(s)
  Kusada, Y. and Fujita-Yamaguchi, Y.
- Journal Title
  
  BisScience Trends 1
  
  Pages: 128-133
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17570120
[Journal Article] An overview of currently available anti-insulin-like growth factor I receptor antibodies2007
- Author(s)
  Kusada, Y., Fujita-Yamaguchi, Y
- Journal Title
  
  Bis Science Trends 1
  
  Pages: 128-133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Journal Article] An overview of currently available anti-insulin-like growth factor I receptor antibodies.2007
- Author(s)
  Kusada, Y. and Fujita-Yamaguchi, Y.
- Journal Title
  
  BisScience Trends 1
  
  Pages: 128-133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17570120
[Journal Article] Downregulation of insulin receptor by antibodies against the type I insulin-like growth factor receptor : implications for anti-insulin-like growth factor therapy in breast cancer2006
- Author(s)
  Sachdev, S., Singh, R., Fujita-Yamaguchi, Y., Yee, D
- Journal Title
  
  Cancer Res 66
  
  Pages: 2391-2402
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Journal Article] Downregulation of insulin receptor by antibodies against the type Iinsulin-like growth factor receptor:implications for anti-insulin-like growth factor therapy in breast cancer2006
- Author(s)
  Sachdev, S., Singh, R., Fujita-Yamaguchi, Y., and Yee, D.
- Journal Title
  
  Cancer Res. 66
  
  Pages: 2391-2402
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Expression and purification of single chain antibodies (scFvs) isolated from aphage-displayed library with LNFPIII (Le^x) probe2011
- Author(s)
  Hiroyuki Kato, Haruhiko Ogawa, Masato Takano, Daiichi Katagiri, Kotaro Kawamoto, Noriyuki Yuasa, Ayano Matsumoto-Takasaki, Yoko Fujita-Yamaguchi
- Organizer
  241^<st> American Chemical Society National Meeting and Exposition
- Place of Presentation
  Anaheim, CA, USA
- Data Source
  KAKENHI-PROJECT-22570125
[Presentation] Purification and characterization of anti-T-antigen single chain antibody expressed in E.coli or the Drosophila Schneider 2 Cell System2011
- Author(s)
  Koyama, T., Matsumoto-Takasaki, A., Yuasa, N., Katagiri, D., Fujita-Yamaguchi, Y.
- Organizer
  The 84th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Kyoto(京都国際会館)
- Data Source
  KAKENHI-PROJECT-22570125
[Presentation] Purification and characterization of anti-LNFPIII single chain antibody (scFv) conjugated with Fc from CHO cells transfected with 3F1 scFv-Fcgene2011
- Author(s)
  Yasunobu Tsuchida, Kaname Funayama, Daisuke Kubo, Noriyuki Yuasa, Yoko Fujita-Yamaguchi
- Organizer
  241^<st> American Chemical Society National Meeting and Exposition
- Place of Presentation
  Anaheim, CA, USA
- Data Source
  KAKENHI-PROJECT-22570125
[Presentation] NMR analysis of an anti-carbohydrate antibody MLS128 single-chain Fv fragment toward elucidation of the multivalent recognition mechanism2011
- Author(s)
  Subedia, G.P., Satoh, T., Hanashima, S., Ikeda, A., Nakada, H., Sato, R., Mizuno, M., Yuasae, N., Fujita-Yamaguchi, Y., Yamaguchi, Y.
- Organizer
  The 50th Memorial Annual Meeting of the Nuclear Magnetic Resonance Society of Japan
- Place of Presentation
  Yokohama (Osanbashi Hall)
- Data Source
  KAKENHI-PROJECT-22570125
[Presentation] In vitro production of anti-carbohydrate antibodies : Purification of anti-trimannose single chain antibodies (scFvs) from inclusion bodies2011
- Author(s)
  Daiichi Katagiri, Tubasa Koyama, Ayano Matsumoto-Takasaki, Nobuyuki Yuasa, Munehiro Nakata, Yoko Fujita-Yamaguchi
- Organizer
  241^<st> American Chemical Society National Meetingand Exposition
- Place of Presentation
  Anaheim, CA, USA
- Data Source
  KAKENHI-PROJECT-22570125
[Presentation] Purification and characterization of anti-Tn-antigen 4E10 single chain antibody expressed in E.coli2011
- Author(s)
  Fukuda, T., Kawamoto, K., Mastumoto-Takasaki, A., Yuasa, N., Fujita-Yamaguchi, Y.
- Organizer
  The 84th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Kyoto(京都国際会館)
- Data Source
  KAKENHI-PROJECT-22570125
[Presentation] Establishment of overproduction procedure for anti-Tn antigen MLS128 single-chain Fv fragment toward the structural studies.2010
- Author(s)
  Subedi, G. P., Satoh, T., Hanashima, S., Ikeda, A, Nakada, H., Sato, R., Mizuno, M., Yuasa, N., Fujita-Yamaguchi, Y., Yamaguchi, Y.
- Organizer
  BMB2010(日本生化学会・分子生物学会)
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Data Source
  KAKENHI-PROJECT-22570125
[Presentation] In vitro production of anti-carbohydrate antibodies : Purification of anti-T-antigen (beta Gall-3GalNAc-Thr/Ser) single chain antibodies (scFvs) from inclusion bodies.2010
- Author(s)
  Matsumoto-Takasaki, A., Yamaguchi, S., Koizumi, T., Yuasa, N., Fujita-Yamaguchi, Y.
- Organizer
  240^<th> American Chemical Society National Meeting and Exposition
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-22570125
[Presentation] Purification and characterization of anti-LNFPIII antibody expressed in CHO cells2010
- Author(s)
  Tsutida, Y., Yuasa, N., Goto, T., Kubo, T., Zhang, W., Fujita-Yamaguchi, Y.
- Organizer
  BMB2010(日本生化学会・分子生物学会)
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Data Source
  KAKENHI-PROJECT-22570125
[Presentation] Establishment of overproduction procedure for anti-Tn antigen MLS128 single-chain Fv fragment toward the structural studies2010
- Author(s)
  Subedi, G. P., Satoh, T., Hanashima, S., Ikeda, A, Nakada, H., Sato, R., Mizuno, M., Yuasa, N., Fujita-Yamaguchi, Y., and Yamaguchi, Y.
- Organizer
  BMB2010 (日本生化学会・分子生物学会)
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Data Source
  KAKENHI-PROJECT-22570125
[Presentation] Refolding and characterization of three anti-mannotriose single chain antibodies2010
- Author(s)
  Katagiri, D., Matsumoto-Takasaki, A., Yuasa, N., Koyama, T., Ogawa, H. Sakai, K., Takayanagi, A., Nakata, M., Fujita-Yamaguchi, Y.
- Organizer
  BMB2010(日本生化学会・分子生物学会)
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Data Source
  KAKENHI-PROJECT-22570125
[Presentation] Comparison of monoclonal antibodies against human IGF-I receptor prepared from mice to those prepared by phage-display technology in votro2007
- Author(s)
  Kusada, Y., Sekine, K., Sato, S., Asanuma, H., Takayanagi, A., Shimizu, N., and Fujita-Yamaguchi, Y.
- Organizer
  WIRC
- Place of Presentation
  Davos,Switzerland
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Comparison of monoclonal antibodies against human IGF-I receptor prepared from mice to those prepared by phage-display technology in vitro2007
- Author(s)
  Kusada, Y., Sekine, K., Sato, S., Asanuma, H., Takayanagi, A., Shimizu, N., Fujita-Yamaguchi, Y
- Place of Presentation
  WIRC, Davos, Switzerland
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Construction and characterzation of single-chain antibodies against insulin-like growth factor-I receptor from hybridomas producing lH7 or 3B7 monoclonal antibody2007
- Author(s)
  Kusada, Y., Matsumoto-Takasaki, A., Asanuma, H., and Fujita-Yamaguchi, Y.
- Organizer
  Antibodies-Euorope.
- Place of Presentation
  Vienna,Austria
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Construction and characterzation of single-chain antibodies against insulin-like growth factor-I receptor from hybridomas producing 1H7 or 3B7 monoclonal antibody2007
- Author(s)
  Kusada, Y., Matsumoto-Takasaki, A., Asanuma, H., Fujita-Yamaguchi, Y
- Organizer
  Antibodies-Euorope
- Place of Presentation
  Vienna, Austria
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Constuction and characterzation of single-chain antibodies against insulin-like growth factor-I receptor from hybridomas producing 1H7 or 3B7 monoclonal antibody2007
- Author(s)
  Kusada, Y, Matsumoto-Takasaki, A., Asanuma, H, and Fujita-Yamaguchi, Y.
- Organizer
  Antibodies-Euorope
- Place of Presentation
  Vienna,Austria
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Down-regulation pathways of insulin-like growth factor I receptor induced by anti-IGFIR antibodies2007
- Author(s)
  Fujita-Yamaguchi, Y., Ohtani, M., Numazaki, M., and Yajima, Y.
- Organizer
  Annual Meeting of ASBMB
- Place of Presentation
  Washington D.C.,USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Down-regulation pathways of insulin-like growth factor I receptor(IGF-IR) induced by anti-IGF-IR antibody in MCF-7 breast cancer cells2007
- Author(s)
  Numazaki, M., Ohtani, M., Yajima, Y., Fujita-Yamaguch, Y
- Organizer
  The 30th Annual Meeting of the Molecular Biology Society of Japan. The 80th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Yokohama, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of human single-chain antibodies against insulin receptor isoform A by phage-display techniques2007
- Author(s)
  Kusada, Y., Sekine, K., Takayanagi, A., Shimizu, N., and Fujita-Yamaguchi, Y.
- Organizer
  11th Annual Meeting of Japanese Society for Molecular Targeted Therapy for Cancer
- Place of Presentation
  Osaka,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Down-regulation pathways of insulin-like growth factor I receptor(IGF-IR)induced by anti-IGF-IR antibody in MCF-7 breast cancer cells2007
- Author(s)
  Numazaki, M., Ohtani, M., Yajima, Y., and Fujita-Yamaguchi, Y.
- Organizer
  The 30tht Annual Meeting of the Molecular Biology Society of Japan.The 80th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Yokohama,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Down-regulation pathways of insulin-like growth factor I receptor (IGF-IR) induced by anti-IGF-IR antibody in MCF-7 breast cancer cells2007
- Author(s)
  Numazaki, M., Ohtani, M., Yajima, Y., and Fujita-Yamachi, Y.
- Organizer
  第30回日本分子生物学会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Down-regulation pathways of insulin-like growth factor I receptor induced by and-IGFIR antibodies2007
- Author(s)
  Fujita-Yamaguchi, Y., Ohtani, M., Numazaki, M., Yajima, Y
- Organizer
  2007 Annual Meeting of ASBMB
- Place of Presentation
  Washington D.C., USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of human single-chain antibodies against insulin receptor isoform A by phage-display techniques2007
- Author(s)
  Kusada, Y, Sekine, K, Takayanagi, A., Shimizu, N., Fujita-Yamaguchi, Y
- Organizer
  11th Annual Meeting of Japanese Society for Molecular Targeted Therapy for Cancer
- Place of Presentation
  Osaka, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Comparison of monoclonal antibodies against human IGF-I receptor prepared from mice to those prepared by phage-display technology in vitro2007
- Author(s)
  Kusada, Y., Sekine, K., Sato, S., Asanuma, H., Takayanagi, A., Shimizu, N., and Fujita-Yamaguchi, Y.
- Organizer
  WIRC
- Place of Presentation
  Davos,Switzerland
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Tokyo,Japan RTK signaling as atarget for cancer intervention strategies:IGF-I receptor signaling intervention2006
- Author(s)
  Yoko Fujita-Yamaguchi
- Organizer
  ICBS2006 RTK Systems Biology Training Course(organized and sponsored by RIKEN Genomic Sciences Center)
- Place of Presentation
  Tokyo,Japan
- Year and Date
  2006-10-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of single-chain antibodies(scFvs)against insulin-like growth factor-I receptor(IGF-IR)and/or insulin receptor isoform A(IR-A)2006
- Author(s)
  Kusada, Y., Sekine, H., Ohtani, M., Sakai, K., Yajima, Y., Takayanagi, A., Shimizu, N., and Fujita-Yamaguchi, Y.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Mechanisms of antibody-mediated insulin-like growth factor I receptor(IGF-IR) down-regulation in MCF-7 breast cancer cells2006
- Author(s)
  Ohtani, M., Yajima, Y., Fujita-Yamaguchi, Y
- Organizer
  The third International Congress of the GRS and the IGF Society
- Place of Presentation
  Kobe, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of single-chain antibodies(scFvs) against insulin-like growth factor-I receptor(IGF-IR) and/or insulin receptor isoform A(IR-A)2006
- Author(s)
  Kusada, Y., Sekine, H., Ohtani, M., Sakai, K., Yajima, Y., Takayanagi, A., Shimizu, N., Fujita-Yamaguchi, Y
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Mechanisms of antibody-mediated insulin-like growth factor I receptor(IGF-IR)down-regulation in MCF-7 breast cancer cells2006
- Author(s)
  Ohtani, M., Yajima, Y., and Fujita-Yamaguchi, Y.
- Organizer
  The third International Congress of the GRS and the IGF Society
- Place of Presentation
  Kobe,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] RTK signaling as atarget for cancer intervention strategies : IGF-I receptor signaling intervention2006
- Author(s)
  Yoko, Fujita-Yamaguchi
- Organizer
  ICBS2006 RTK Systems Biology Training Course(organized and sponsored by RIKEN Genomic Sciences Center)
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2006-10-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of human single-chain antibodies(scFv)against insulin-like growth factor I receptor(IGF-IR)2005
- Author(s)
  Kusada, Y., Morizono, T., Sakai, K., Takayanagi, A., Shimizu, N., and Fujita-Yamaguchi, Y.
- Organizer
  78th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Kobe,Japan.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Mechanisms of antibody-mediated insulin-like growth factor I receptor(IGF-IR)down-regulation2005
- Author(s)
  Ootani, M., Yajima, Y., and Fujita-Yamaguchi, Y.
- Organizer
  78th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Kobe,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of human single-chain antibodies(scFv) against insulin-like growth factor I receptor(IGF-IR)2005
- Author(s)
  Kusada, Y., Morizono, T., Sakai, K., Takayanagi, A., Shimizu, N., Fujita-Yamaguchi, Y
- Organizer
  78th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Kobe, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Mechanisms of antibody-mediated insulin-like growth factor I receptor(IGF-IR) down-regulation2005
- Author(s)
  Ootani, M., Yajima, Y., Fujita-Yamaguchi, Y
- Organizer
  78th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Kobe, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120

1. YAMAGUCHI Yoshiki (90323451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
2. TAKAYANAGI Atsushi (80245464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results

Yamaguchi Yoko 山口 陽子

YAMAGUCHI Yoko 山口 陽子

FUJITA Yoko 山口 陽子

Research Projects

Research Products

Co-Researchers

SHAレクチン結合性糖鎖から紐解く膵がん発症機構の解明と早期診断への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Expression of novel carbohydrate-specific single chain antibodies in E. coli and analyses of carbohydrate-binding activities of purified antibodiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Insulin-like growth factor-I receptor-targeted cancer therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Construction and expression of anti-Tn-antigen-specific single chain antibody genes from hybridoma producing MLS128 monoclonal antibody2012

Author(s)

Journal Title

Data Source

[Journal Article] Surface plasmon resonance and NMR analyses of anti Tn-antigen MLS128 monoclonal antibody binding to two or three consecutive Tn-antigen cluster2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Construction and expression of anti-Tn-antigen-specific single chain antibody genes from hybridoma producing MLS128 monoclonal antibody2012

Author(s)

Journal Title

Data Source

[Journal Article] Surface plasmon resonance and NMR analyses of anti Tn-antigen MLS128 monoclonal antibody binding to two or three consecutive Tn-antigen cluster2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Overproduction of anti-Tn antibody MLS128 single-chain Fv fragment in Escherichia coli cytoplasm using a novel pCold-PDI vector2012

Author(s)

Journal Title

Data Source

[Journal Article] Overproduction of anti-Tn antibody MLS128 single-chain Fv fragment in Escherichia coli cytoplasm using a novel pCold-PDI vector2012

Author(s)

Journal Title

Data Source

[Journal Article] Effects of two monoclonal antibodies, MLS128 against Tn-antigen and 1H7 against insulin-like growth factor-I receptor, on the growth of colon cancer cells2012

Author(s)

Journal Title

Data Source

[Journal Article] がん診断薬・抗体療法向け創薬を目指した糖鎖特異的ヒト型抗体の開発2011

Author(s)

Journal Title

Data Source

[Journal Article] Characterization of three different single chain antibodies recognizing non reducing terminal mannose residues expressed in Escherichia coli by an inducible T7 expression system2011

Author(s)

Journal Title

Data Source

[Journal Article] Characterization of three different single chain antibodies recognizing nonreducing terminal mannose residues expressed in Escherichia coli by an inducible T7 expression system2011

Author(s)

Journal Title

Data Source

[Journal Article] Preparation of asialo-agalacto-glycophorin A for screening of and-Tn antibodies.2010

Author(s)

Journal Title

Data Source

[Journal Article] Preparation of asialo-agalacto- glycophorin A for screening of anti-Tn antibodies2010

Author(s)

Journal Title

Data Source

[Journal Article] Production of anti-carbohydrate antibodies by phage-display technologies: Potential impairment of cell growth as a result of endogenous expression2010

Author(s)

Journal Title

Data Source

[Journal Article] Production of anti-carbohydrate antibodies by phage-display technologies : Potential impairment of cell growth as a result of endogenous expression.2010

Author(s)

Yamaguchi Yoko 山口陽子

YAMAGUCHI Yoko 山口陽子

FUJITA Yoko 山口陽子