TAKAYANAGI Atsushi 高柳淳

… Alternative Names

Researcher Number	80245464
Other IDs
Affiliation (based on the past Project Information) *help	2016: 慶應義塾大学, 医学部(信濃町), 共同研究員 2005 – 2016: 慶應義塾大学, 医学部, 講師 2010: 慶応義塾大学, 医学部, 講師 1996 – 2002: 慶應義塾大学, 医学部, 助手 1998: School of Medicine,KEIO University Instructor, 医学部, 助手 … More
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological Sciences / General surgery / Tumor diagnosis Except Principal Investigator 膠原病・アレルギー・感染症内科学 / Digestive surgery / Molecular biology / General surgery / Ophthalmology / General fisheries … More
Keywords	Principal Investigator 抗体 / 遺伝子治療 / 一本鎖抗体 / イムノジーン / 遺伝子導入 / EGFレセプター / 扁平上皮癌 / EGFR / ヒト型化 / 細胞特異的 … More Except Principal Investigator 遺伝子治療 / 遺伝子導入 / 自己免疫疾患 / ゼブラフィッシュ / HMGB1 / イムノジーン / 劇症肝不全 / 肝移植 / RNA修飾 / 急性肝不全 / EGFレセプター / エンドサイトーシス / モノクローナル抗体 / 肝臓外科学 / 人工抗体 / ノンコーディングRNA / サイトカイン / 体外循環 / リボソーム / 抗RNA抗体 / リボソームRNA / snoRNA / sRAGE / 肝細胞移植 / Autoimmune disease / APECED / APS-1 / AIRE / CBP / downregulation / 細胞増殖シグナル伝達 / アンチセンス発現ベクター / 80K蛋白質 / 改変型MTプロモーター / Bacurovirus / 遺伝子解析 / 部位特異的変異導入法 / 抗体 / イムノポーター / ジフテリア毒素 / 一本鎖抗体 / ターゲッティング / HMGB-1 / 抗サイトカイン療法 / 生体肝移植 / SLE / モルフォリノアンチセンスオリゴ / ファージディスプレイ / 人工杭体 / アデノウィルス / 人工肝臓 / 治療 / 吸着治療 / 翻訳 / 造血異常 / 発がん / 核小体 / p53 / リボソーム病 / 疾患モデル / RNA抗体 / 人工抗体ライブラリー / 肝虚血再灌流 / 肝虚血再灌流障害モデル / 移植・再生医療 / ウィルス / 遺伝子 / バイオリアクター / 遺伝・育種 / イルカ / 形態 / 後肢 / ゲノム解析 / 不死化 / iPS細胞 / Tursiops / ホメオボックス遺伝子 / sTLR / 自己免疫 / snRNA / scaRNA / rRNA / ディスケリン / ゼブラフィッシュモデル / 可溶性受容体 / RAGE / 自己免疫性疾患 / 天疱瘡 / B細胞 / 疾患特異的治療法 / 組換え毒素 / カドヘリン / デスモグレイン / 細胞接着 / Pemphigus / B cell / Disease-specific therapy / Recombinant toxin / Cadherin / Desmoglein / Cell adhesion / 悪性黒色腫 / 眼内腫瘍 / 人工一本鎖抗体 / melanoma / intra ocular tumor / gene therapy / monoclonal antibody / artificial antibody / immunogene / 胸腺 / 抗原提示細胞 / 樹状細胞 / SV40T抗原 / トランスジェニックマウス / 免疫応答 / RelB / 転写調節因子 / Thymus / Antigen presenting cells / Dendritic cells / 網膜神経節細胞 / プロモーター / マウスアミンオキシダーゼ / レーベル病 / イデベノン / ヒトアミンオキシダーゼ / ベクター / retinal ganglion cell / promotor / mause amine oxidase / Leber's disease / idebenone / human amine oxidase / IκB / NFκB / アンチセンス / 肝虚血再灌流障害 / IkB / NFkB / 肝虚血再灌流傷害 / IкB / NFкB / antisence / genetransfer / ischemia-reperfusion injury / liver transplantation / 抗IGF-I受容体 / 単鎖抗体 / がん分子標的治療法 / ダウンレギュレーション / 抗がん効果 / 抗IGF-I 受容体 / ヒト単鎖抗体 / Phage display法 / Anti-IGF-I receptor / single chain antibody / cancer molecular thera / Anti-tumor erowth / human papillomavirus / vaccine / cervical cancer / 子宮頸癌 / ワクチン / ヒトパピローマウイルス / 子宮頸がん / パピローマウイルス / マイクロRNA Less

Treatment for fulminant hepatitis focusing on soluble receptor for HMGB1 (sRAGE)
- Principal Investigator
  
  Shinoda Masahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Keio University
Elucidation of molecular mechanism of cervical cancer and its clinical application
- Principal Investigator
  
  Fujii Takuma
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Fujita Health University
Developments of A New Antibody Library and Antibody ChipsPrincipal Investigator
- Principal Investigator
  
  TAKAYANAGI Atsushi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Keio University
Development of a new effective therapy of fulminant hepatitis to focus on sTLR.
- Principal Investigator
  
  TANABE Minoru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Keio University
Loss of RNA modification and autoimmune diseases: a novel mechanism of the SLE pathogenesis
- Principal Investigator
  
  KENMOCHI Naoya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Miyazaki
Development of a new effective therapy of ischemia reperfusion injury of liver and small intestine.
- Principal Investigator
  
  SINODA Masahiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Keio University
Ribosomal abnormalities and human diseases: Molecular pathogenesis of ribosomopathies
- Principal Investigator
  
  KENMOCHI Naoya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  University of Miyazaki
RNA modification and self-discrimination : A possible link to the pathogenesis of autoimmune disease
- Principal Investigator
  
  KENMOCHI Naoya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Miyazaki
Molelucar Biological Analysis for the mechanism of the hind limb formation of the dolphin with fin-shaped hind limbs
- Principal Investigator
  
  YOSHIOKA Motoi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General fisheries
- Research Institution
  Mie University
Investigation of the treatment of fulminant hepatitis by inhibition of HMGB1
- Principal Investigator
  
  TANABE Minoru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Keio University
Autoimmune diseases and RNA modifications: Molecular mechanism of pathogenesis of systemic lupus erythematosus.
- Principal Investigator
  
  UECHI Tamayo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Molecular biology
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Miyazaki
Establishment of an effective therapy for fulminant hepatic failure focusing on IL-18 inhibition
- Principal Investigator
  
  TANABE Minoru
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Keio University
Insulin-like growth factor-I receptor-targeted cancer therapy
- Principal Investigator
  
  FUJITA Yoko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokai University
抗体を利用した遺伝子導入法「ヒト型イムノジーン法」の開発Principal Investigator
- Principal Investigator
  
  高柳淳
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Keio University
Prevention of hepatic ischemia-reperfusion injury by gene transfer of IкB antisense and its application to liver transplantation
- Principal Investigator
  
  SHIMAZU Motohide
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Keio University
抗体を利用した遺伝子導入法「組換えイムノジーン法」の改良Principal Investigator
- Principal Investigator
  
  高柳淳
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Study of theretinal ganglion cell specific gene, optic atrophy, and gene threrapy
- Principal Investigator
  
  MASHIMA Yukihiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Roles of the Autoimmune Regulator (AIRE) Gene in Immune Response
- Principal Investigator
  
  SHIMIZU Nobuyoshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Endocrinology
- Research Institution
  Keio University
ヒト型人工抗体を用いた細胞特異的生体内遺伝子導入法の開発Principal Investigator
- Principal Investigator
  
  高柳淳
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
Development of antigen-specific B cell elimination by recombinant toxins in autoimmune diseases
- Principal Investigator
  
  AMAGAI Masayuki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Keio University
Gene Therapy for Melanoma Using Artificial Antibody/DNA Complex
- Principal Investigator
  
  OHTAKE Yuichiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  KEIO University
ヒトEGFレセプターを標的とする人工抗体を用いた生体内遺伝子導入法の開発Principal Investigator
- Principal Investigator
  
  高柳淳
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University
モノクローナル抗体や一本鎖人工抗体を用いた遺伝子導入法による癌の遺伝子治療
- Principal Investigator
  
  清水信義
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Keio University
抗体を利用した生体内遺伝子ターゲッティング法の開発と癌遺伝子治療への応用
- Principal Investigator
  
  清水信義
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Keio University
細胞増殖シグナル伝達に関わる80K蛋白遺伝子の構造解析と転写制御
- Principal Investigator
  
  SHIMIZU Nobuyoshi
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Keio University

All 2016 2014 2013 2012 2011 2010 2008 2007 2006 2005

All Journal Article Presentation Patent

[Journal Article] Therapeutic Potential of Transgenic Mesenchymal Stem Cells Engineered to Mediate Anti-High Mobility Group Box 1 Activity: Targeting of Colon Cancer2014
- Author(s)
  Kikuchi, H., Yagi, H., Hasegawa, H., Ishii, Y., Okabayashi, K., Tsuruta, M. Go, H., Takayanagi, A. Kitagawa, Y.
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 190 Pages: 134-143
- DOI
  10.1016/j.jss.2014.02.047
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24501343
[Journal Article] Recombinant human IgG antibodies recognizing distinct extracellular domains of EGF receptor exhibit different degrees of growth inhibitory effects on human A431 cancer cells2013
- Author(s)
  Chang, C., Takayanagi, A., Yoshida, T., Shimizu, N.
- Journal Title
  
  EXPERIMENTAL CELL RESEARCH
  
  Volume: 319 Pages: 1146-1155
- DOI
  10.1016/j.yexcr.2013.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501343
[Journal Article] Screening of scFv-displaying phages recognizing distinct extracellular domains of EGF receptor by target-guided proximity labeling method2011
- Author(s)
  Chang, C., Takayanagi, A., Yoshida, T. and Shimizu, N.
- Journal Title
  
  J. Immunol. Methods
  
  Volume: 372 Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659186
[Journal Article] Screening of scFv-displaying phages recognizing distinct extracellular domains of EGF receptor by target-guided proximity labeling method.2011
- Author(s)
  Chang C, Takayanagi A, Yoshida T, Shimizu N.
- Journal Title
  
  J Immunol Methods
  
  Volume: 372 Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200070
[Journal Article] Construction and characterization of single-chain antibodies against human insulin-like growth factor-I receptor from hybridomas producing 1H7 or 3B7 monoclonal antibody2008
- Author(s)
  Kusada Y, Morizono T, Matsumoto-Takasaki A, Sakai K, Sato S, Asanuma H, Takayanagi A, Fujita-Yamaguchi Y.
- Journal Title
  
  J Biochem
  
  Volume: 143 Pages: 9-19
- NAID
  10024907273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200070
[Journal Article] Construction and characterization of single-chain antibodies against human insulin-like growth factor-1 Receptor from hybridomas producing 1H7 and 3B7 monoclonal antibody2008
- Author(s)
  Kusada, Y, Morizono, T., Matsumoto-Takasaki, A., Sakai, K., Sato, S., Asanuma, H., Takayanagi, A., and Fujita-Yamaguchi, Y.
- Journal Title
  
  J.Biochem. 143
  
  Pages: 9-19
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17570120
[Journal Article] Construction and characterization of single-chain antibodies against human insulin-like growth factor-1 Receptor from hybridomas producing 1H7 and 3B7 monoclonal antibody2008
- Author(s)
  Kusada, Y, Morizono, T., Matsumoto-Takasaki, A., Sakai, K., Sato, S., Asanuma, H., Takayanagi, A., Fujita-Yamaguchi, Y
- Journal Title
  
  J. Biochem 143
  
  Pages: 9-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Patent] Antibody and Use Thereof2012
- Inventor(s)
  清水信義、高柳淳、吉田徹彦
- Industrial Property Rights Holder
  慶應義塾大学、東亞合成株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2012-12-04
- Overseas
- Data Source
  KAKENHI-PROJECT-24501343
[Patent] 抗RNA抗体のスクリーニング方法及びRNA抗体の製造方法2011
- Inventor(s)
  剣持直哉、吉浜麻生、高柳淳、清水信義
- Industrial Property Rights Holder
  剣持直哉、吉浜麻生、高柳淳、清水信義
- Industrial Property Number
  2011-098698
- Filing Date
  2011-04-26
- Data Source
  KAKENHI-PROJECT-22370065
[Patent] 抗RNA抗体のスクリーニング方法及びRNA抗体の製造方法2011
- Inventor(s)
  剣持直哉、吉浜麻生、高柳淳、清水信義
- Industrial Property Rights Holder
  宮崎大学、慶應義塾
- Filing Date
  2011-04-26
- Data Source
  KAKENHI-PROJECT-22659186
[Patent] 抗RNA抗体のスクリーニング方法及びRNA抗体の製造方法2011
- Inventor(s)
  剣持直哉,吉浜麻生,高柳淳,清水信義
- Industrial Property Rights Holder
  宮崎大学,慶慮義塾大学
- Industrial Property Number
  2011-098698
- Filing Date
  2011-04-26
- Data Source
  KAKENHI-PROJECT-22370065
[Patent] 抗RNA抗体のスクリーニング方法2011
- Inventor(s)
  剣持直哉, 吉浜麻生, 高柳淳, 清水信義.
- Industrial Property Rights Holder
  宮崎大学, 慶應義塾
- Filing Date
  2011-04-26
- Data Source
  KAKENHI-PROJECT-20200070
[Patent] 抗RNA抗体のスクリーニング方法2011
- Inventor(s)
  剣持直哉、吉浜麻生、高柳淳、清水信義
- Industrial Property Rights Holder
  宮崎大学、慶應義塾
- Industrial Property Number
  2011-098698
- Filing Date
  2011-04-26
- Data Source
  KAKENHI-PROJECT-20200070
[Patent] 抗RNA抗体のスクリーニング方法及びRNA抗体の製造方法2011
- Inventor(s)
  剣持直哉、吉浜麻生、高柳淳、清水信義
- Industrial Property Rights Holder
  剣持直哉、吉浜麻生、高柳淳、清水信義
- Industrial Property Number
  2011-098698
- Filing Date
  2011-04-26
- Data Source
  KAKENHI-PROJECT-22659186
[Presentation] HMGB1 targeting therapy for acute liver failure.2016
- Author(s)
  篠田昌宏、溝田高聖, 雨宮隆介, 西山亮, 高柳淳, 島田薫, 海老沼浩利, 尾原秀明, 板野理, 北川雄光
- Organizer
  第71回日本消化器外科学会総会
- Place of Presentation
  アスティ徳島（徳島県徳島市）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-26430093
[Presentation] HMGB1に着目した急性肝不全の病態理解と治療法の開発2013
- Author(s)
  篠田昌宏, 田中真之, 西山亮, 大島剛, 高野公徳, 海老沼浩利, 高柳淳, 山田晋吾, 宮庄拓, 須田康一, 林田哲, 八木洋, 阿部雄太, 日比泰造, 北郷実, 尾原秀明, 竹内裕也, 板野理, 丸山征郎, 田邉稔, 北川雄光
- Organizer
  第39回日本急性肝不全研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591888
[Presentation] HMGB1に着目した急性肝不全の病態理解と体外循環吸着療法の可能性2013
- Author(s)
  田中真之, 篠田昌宏, 西山亮, 高野公徳, 高柳淳, 丸山征郎, 田邉稔, 北川雄光
- Organizer
  第49回日本移植学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24591888
[Presentation] ラット急性肝不全モデルにおけるHMGB1 A box遺伝子導入の効果2013
- Author(s)
  雨宮隆介, 篠田昌宏, 田中真之, 高柳淳, 西山亮, 大島剛, 山田晋吾, 宮庄拓, 須田康一, 八木洋, 林田哲, 阿部雄太, 日比泰造, 北郷実, 尾原秀明, 竹内裕也, 板野理, 丸山征郎, 田邉稔, 北川雄光
- Organizer
  第20回外科侵襲とサイトカイン研究会
- Place of Presentation
  渋川
- Data Source
  KAKENHI-PROJECT-24591888
[Presentation] HMGB1制御による急性肝不全に対する新治療の開発2013
- Author(s)
  篠田昌宏,田邉稔,田中真之,西山亮,大島剛,高野公徳,海老沼浩利,高柳淳,山田晋吾,宮庄拓,須田康一,林田哲,八木洋,阿部雄太,日比泰造,北郷実,田中克典,尾原秀明,竹内裕也,板野理,丸山征郎,北川雄光
- Organizer
  第40回日本集中治療医学会学術集会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-23591875
[Presentation] HMGB1に着目した急性肝不全の病態理解と治療法の開発2013
- Author(s)
  篠田昌宏,田中真之,西山亮,大島剛,高野公徳,海老沼浩利,高柳淳,山田晋吾,宮庄拓,須田康一,林田哲,八木洋,阿部雄太,日比泰造,北郷実,尾原秀明,竹内裕也,板野理,丸山征郎,田邉稔,北川雄光
- Organizer
  第39回日本急性肝不全研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591875
[Presentation] HMGB1 A box domainの遺伝子導入方法の確立2013
- Author(s)
  田中真之, 篠田昌宏, 高柳淳, 西山亮, 大島剛, 高野公徳, 山田晋吾, 宮庄拓, 須田康一, 林田哲, 八木洋, 阿部雄太, 日比泰造, 北郷実, 尾原秀明, 竹内裕也, 板野理, 丸山征郎, 田邉稔, 北川雄光
- Organizer
  第40回日本臓器保存生物医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591875
[Presentation] HMGB1 A box domainの遺伝子導入方法の確立2013
- Author(s)
  田中真之, 篠田昌宏, 高柳淳, 西山亮, 大島剛, 高野公徳, 山田晋吾, 宮庄拓, 須田康一, 林田哲, 八木洋, 阿部雄太, 日比泰造, 北郷実, 尾原秀明, 竹内裕也, 板野理, 丸山征郎, 田邉稔, 北川雄光
- Organizer
  第40回日本臓器保存生物医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591888
[Presentation] ラット急性肝不全モデルにおけるHMGB1 A box遺伝子導入の効果2013
- Author(s)
  雨宮隆介, 篠田昌宏, 田中真之, 高柳淳, 西山亮, 大島剛, 山田晋吾, 宮庄拓, 須田康一, 八木洋, 林田哲, 阿部雄太, 日比泰造, 北郷実, 尾原秀明, 竹内裕也, 板野理, 丸山征郎, 田邉稔, 北川雄光
- Organizer
  第20回外科侵襲とサイトカイン研究会
- Place of Presentation
  渋川
- Data Source
  KAKENHI-PROJECT-23591875
[Presentation] HMGB1に着目した急性肝不全の病態理解と体外循環吸着療法の可能性2013
- Author(s)
  田中真之, 篠田昌宏, 西山亮, 高野公徳, 高柳淳, 丸山征郎, 田邉稔, 北川雄光
- Organizer
  第49回日本移植学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591875
[Presentation] 急性肝不全患者におけるHMGB1動態と動物モデルにおけるHMGB1制御の効果2012
- Author(s)
  篠田昌宏,田邉稔,高野公徳,大島剛,西山亮,海老沼浩利,高柳淳,山田晋吾,宮庄拓,松原健太郎,須田康一,林田哲,八木洋,尾原秀明,竹内裕也,板野理,河地茂行,斉藤英胤,日比紀文,丸山征郎,北川雄光
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-23591875
[Presentation] A New Periplasmic Chaperon Vector for Improvement of Phage-Displayed Antibody Library2012
- Author(s)
  Atsushi Takayanagi, Tetsuhiko Yoshida, Nobuyoshi Shimizu
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24501343
[Presentation] HMGB1阻害タンパクA boxの遺伝子導入ベクタ-の確立とラット急性肝不全モデルにおける予後改善効果2012
- Author(s)
  篠田昌宏,田邉稔,西山亮,高柳淳,大島剛,田中真之,山田晋吾,宮庄拓,須田康一,福永興壱,八木洋,林田哲,松原健太郎,北郷実,尾原秀明,竹内裕也,板野理,河地茂行,丸山征朗,北川雄光
- Organizer
  第48回日本腹部救急医学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23591875
[Presentation] HMGB1 A box遺伝子導入ベクタ-の樹立とラット急性肝不全モデルにおける予後改善効果2012
- Author(s)
  篠田昌宏,田邉稔,西山亮,高柳淳,大島剛,田中真之,山田晋吾,宮庄拓,須田康一,松原健太郎,八木洋,林田哲,北郷実,尾原秀明,竹内裕也,板野理,福永興壱,河地茂行,丸山征朗,北川雄光
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591875
[Presentation] HMGB1阻害タンパクA boxの遺伝子導入ベクターの確立とラット急性肝不全モデルにおける予後改善効果2012
- Author(s)
  篠田昌宏, 田邉稔, 西山亮, 高柳淳, 大島剛, 田中真之, 山田晋吾, 宮庄拓, 須田康一, 福永興壱, 八木洋, 林田哲, 松原健太郎, 北郷実, 尾原秀明, 竹内裕也, 板野理, 河地茂行, 丸山征朗, 北川雄光
- Organizer
  第48回日本腹部救急医学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Gene transfer of a box domain from high mobility group box 1 in rat acute liver failure model2011
- Author(s)
  Shinoda M, Tanabe M, Takayanagi A, Nishiyama R, Oshima G, Yagi H, Maruyama I, Kitagawa Y
- Organizer
  International Surgical Week ISW 2011
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] HMGB1制御による急性肝不全に対する新治療の開発.2011
- Author(s)
  篠田昌宏, 田邉稔, 高野公徳, 大島剛, 西山亮, 海老沼浩利, 高柳淳, 山田晋吾, 宮庄拓, 福永興壱, 松原健太郎, 須田康一, 林田哲, 八木洋, 尾原秀明, 竹内裕也, 板野理, 河地茂行, 斎藤英胤, 日比紀文, 丸山征郎, 北川雄光
- Organizer
  第1回HMGB1シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2011-02-26
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Gene Transfer of the A box domain of HMGB1 into the Liver in rat acute liver failure model2011
- Author(s)
  Shinoda M, Tanabe M, Nishiyama R, Takayanagi A, Oshima G, Takano K, Yagi H, Kawachi S, Maruyama I, Kitagawa Y
- Organizer
  97th American College of Surgeons Clinical Congre
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Establishment of rat hepatocyte producing high mobility group box 1 inhibitor2011
- Author(s)
  Shinoda M, Nishiyama R, Tanabe M, Takayanagi A, Oshima G, Takano K, Sanuki N, Nagarekawa T, Miyasho T, Yamada S, Fukunaga K, Suda K, Matsubara K, Obara H, Takeuchi H, Itano O, Kawachi S, Maruyama I, Kitagawa Y
- Organizer
  XXXVIII Congress of the European Society for Artificial Organs(ESAO 2011) and IV Biennial Congress of the International Federation on Artificial Organs(IFAO 2011)
- Place of Presentation
  Portugal
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Gene Transfer of the High Mobility Group Box 1 Inhibitor in Rat Acute Liver Failure Model.2011
- Author(s)
  Shinoda M, Tanabe M, Takayanagi A, et al.
- Organizer
  The 2011 Joint International Congress of ILTS, ELITA, & LICAGE
- Place of Presentation
  Valencia
- Data Source
  KAKENHI-PROJECT-23591875
[Presentation] Efficient Production of Recombinant Antibodies in Mammalian Cells by Transient Transfection of Expression Vectors with 2.5K "PEI-MAX"2011
- Author(s)
  高柳淳, 吉田徹彦, 清水信義
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22659186
[Presentation] Gene Transfer of the High Mobility Group Box 1 Inhibitor in Rat Acute Liver Failure Model2011
- Author(s)
  Shinoda M, Tanabe M, Takayanagi A, Nishiyama R, Oshima G, Takano K, Yagi H, Suda K, Takeuchi H, Hayashida T, Yamada S, Miyasho T, Fukunaga K, Obara H, Itano O, Kawachi S, Maruyama I, Kitagawa Y
- Organizer
  The 2011 Joint International Congress of ILTS
- Place of Presentation
  ELITA, & LICAGE, Valencia
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Gene Transfer of the A box domain of HMGB1 into the Liver in rat acute liver failure model2011
- Author(s)
  Shinoda M, Tanabe M, Nishiyama R, Takayanagi A, Oshima G, Takano K, Yagi H, Kawachi S, Maruyama I, Kitagawa Y
- Organizer
  97th American College of Surgeons Clinical Congress
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-23591875
[Presentation] Gene Transfer of the High Mobility Group Box 1 Inhibitor in Rat Acute Liver Failure Model2011
- Author(s)
  Shinoda M, Tanabe M, Takayanagi A, et al
- Organizer
  The 2011 Joint International Congress of ILTS, ELITA, & LICAGE
- Place of Presentation
  Valencia, Spain
- Year and Date
  2011-06-22
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] ラット急性肝不全モデルにおけるHMGB1阻害タンパク遺伝子導入による治療効果の検討2011
- Author(s)
  西山亮, 篠田昌宏, 田邉稔, 高柳淳, 大島剛, 八木洋, 竹内裕也, 河地茂行, 丸山征郎, 北川雄光
- Organizer
  第66回日本消化器外科学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] HMGB1阻害タンパクA boxの遺伝子導入ベクターの確立とラット急性肝不全モデルにおける予後改善効果2011
- Author(s)
  田中真之, 篠田昌宏, 田邉稔, 西山亮, 高柳淳, 大島剛, 山田晋吾, 宮庄拓, 須田康一, 松原健太郎, 八木洋, 林田哲, 北郷実, 尾原秀明, 竹内裕也, 板野理, 河地茂行, 丸山征郎, 北川雄光
- Organizer
  第18回外科侵襲とサイトカイン研究会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Gene transfer of a box domain from high mobility group box 1 in rat acute liver failure model2011
- Author(s)
  Shinoda M, Tanabe M, Takayanagi A, et al
- Organizer
  International Surgical Week ISW 2011
- Place of Presentation
  Pacifico Yokohama, Japan
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Serum level of high mobility group box 1 in patients with fulminant hepatic failure and its blockade in rat model.2010
- Author(s)
  Oshima G, Shinoda M, Tanabe M, Takayanagi A, Miyasho T, Yamada S, Ebinuma H, Takano K, Hibi T, Suda K, Obara H, Takeuchi H, Kawachi S, Fukunaga K, Hibi T, Maruyama I, Kitagawa Y.
- Organizer
  ILTS 16th Annual International Congress
- Place of Presentation
  Hong Kong
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Serum high-mobility group box 1 level in the patients with fulminant hepatic failure and its blockade effect in rat model2010
- Author(s)
  Oshima G, Shinoda M, Tanabe M, Takayanagi A, Miyasho T, Yamada S, Ebinuma H, Takano K, Hibi T, Suda K, Obara H, Takeuchi H, Kawachi S, Fukunaga K, Hibi T, Maruyama I, Kitagawa Y
- Organizer
  45th Annual Meeting of the European Association for the Study of the Liver(EASL)-The International Liver Congress 2010-
- Place of Presentation
  Vienna
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Serum level of high mobility group box 1 in patients with fulminant hepatic failure and its blockade in rat model2010
- Author(s)
  Oshima G, Shinoda M, Tanabe M, Takayanagi A, Miyasho T, Yamada S, Ebinuma H, Takano K, Hibi T, Suda K, Obara H, Takeuchi H, Kawachi S, Fukunaga K, Hibi T, Maruyama I, Kitagawa Y
- Organizer
  ILTS 16th Annual International Congress
- Place of Presentation
  Hong Kong
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Serum high-mobility group box 1 level in the patients with fulminant hepatic failure and its blockade effect in rat model.2010
- Author(s)
  Oshima G, Shinoda M, Tanabe M, Takayanagi A, Miyasho T, Yamada S, Ebinuma H, Takano K, Hibi T, Suda K, Obara H, Takeuchi H, Kawachi S, Fukunaga K, Hibi T, Maruyama I, Kitagawa Y.
- Organizer
  45th Annual Meeting of the European Association for the Study of the Liver (EASL) -The International Liver Congress 2010-
- Place of Presentation
  Vienna
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Serum high mobility group box 1 level in the patients with fulminant hepatic failure and its blockade in rat model2010
- Author(s)
  Shinoda M, Tanabe M, Oshima G, Takayanagi A, Miyasho T, Yamada S, Ebinuma H, Takano K, Hibi T, Suda K, Obara H, Takeuchi H, Kawachi S, Fukunaga K, Saito H, Hibi T, Maruyama I, Kitagawa Y
- Organizer
  The 4th International HMGB1 Symposium
- Place of Presentation
  Helsinki
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] ヒトゲノム情報と人工抗体ライブラリーを活用したプロテオーム解析の新戦略2010
- Author(s)
  高柳淳
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22659186
[Presentation] Serum high mobility group box 1 level in the patients with fulminant hepatic failure and its blockade in rat model.2010
- Author(s)
  Shinoda M, Tanabe M, Oshima G, Takayanagi A, Miyasho T, Yamada S, Ebinuma H, Takano K, Hibi T, Suda K, Obara H, Takeuchi H, Kawachi S, Fukunaga K, Saito H, Hibi T, Maruyama I, Kitagawa Y.
- Organizer
  The 4th International HMGB1 Symposium
- Place of Presentation
  Helsinki
- Year and Date
  2010-06-22
- Data Source
  KAKENHI-PROJECT-21591762
[Presentation] Comparison of monoclonal antibodies against human IGF-I receptor prepared from mice to those prepared by phage-display technology in votro2007
- Author(s)
  Kusada, Y., Sekine, K., Sato, S., Asanuma, H., Takayanagi, A., Shimizu, N., and Fujita-Yamaguchi, Y.
- Organizer
  WIRC
- Place of Presentation
  Davos,Switzerland
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Comparison of monoclonal antibodies against human IGF-I receptor prepared from mice to those prepared by phage-display technology in vitro2007
- Author(s)
  Kusada, Y., Sekine, K., Sato, S., Asanuma, H., Takayanagi, A., Shimizu, N., Fujita-Yamaguchi, Y
- Place of Presentation
  WIRC, Davos, Switzerland
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of human single-chain antibodies against insulin receptor isoform A by phage-display techniques2007
- Author(s)
  Kusada, Y., Sekine, K., Takayanagi, A., Shimizu, N., and Fujita-Yamaguchi, Y.
- Organizer
  11th Annual Meeting of Japanese Society for Molecular Targeted Therapy for Cancer
- Place of Presentation
  Osaka,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of human single-chain antibodies against insulin receptor isoform A by phage-display techniques2007
- Author(s)
  Kusada, Y, Sekine, K, Takayanagi, A., Shimizu, N., Fujita-Yamaguchi, Y
- Organizer
  11th Annual Meeting of Japanese Society for Molecular Targeted Therapy for Cancer
- Place of Presentation
  Osaka, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Comparison of monoclonal antibodies against human IGF-I receptor prepared from mice to those prepared by phage-display technology in vitro2007
- Author(s)
  Kusada, Y., Sekine, K., Sato, S., Asanuma, H., Takayanagi, A., Shimizu, N., and Fujita-Yamaguchi, Y.
- Organizer
  WIRC
- Place of Presentation
  Davos,Switzerland
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of single-chain antibodies(scFvs)against insulin-like growth factor-I receptor(IGF-IR)and/or insulin receptor isoform A(IR-A)2006
- Author(s)
  Kusada, Y., Sekine, H., Ohtani, M., Sakai, K., Yajima, Y., Takayanagi, A., Shimizu, N., and Fujita-Yamaguchi, Y.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of single-chain antibodies(scFvs) against insulin-like growth factor-I receptor(IGF-IR) and/or insulin receptor isoform A(IR-A)2006
- Author(s)
  Kusada, Y., Sekine, H., Ohtani, M., Sakai, K., Yajima, Y., Takayanagi, A., Shimizu, N., Fujita-Yamaguchi, Y
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of human single-chain antibodies(scFv)against insulin-like growth factor I receptor(IGF-IR)2005
- Author(s)
  Kusada, Y., Morizono, T., Sakai, K., Takayanagi, A., Shimizu, N., and Fujita-Yamaguchi, Y.
- Organizer
  78th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Kobe,Japan.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570120
[Presentation] Isolation and characterization of human single-chain antibodies(scFv) against insulin-like growth factor I receptor(IGF-IR)2005
- Author(s)
  Kusada, Y., Morizono, T., Sakai, K., Takayanagi, A., Shimizu, N., Fujita-Yamaguchi, Y
- Organizer
  78th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Kobe, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570120

1. SHINODA Masahiro (50286499)

# of Collaborated Projects: 6 results

# of Collaborated Products: 31 results
2. SHIMIZU Nobuyoshi (50162706)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. TANABE Minoru (50197513)

# of Collaborated Projects: 4 results

# of Collaborated Products: 30 results
4. KENMOCHI Naoya (00133124)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. 蒲生忍 (90122308)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. OHTAKE Yuichiro (30233159)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MASHIMA Yukihiro (40157186)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NISHIYAMA Ryo (70528322)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
9. ASAKAWA Shuichi (30231872)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. KUDOH Jun (80178003)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 陳嘉竝 (10296725)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. UECHI Tamayo (10381104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAKAMI Yasunari (80236356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HIGA Sayomi (20381105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SUZUKI Tsutomu (20292782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YOSHIOKA Motoi (30262992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KATO Hidehiro (30371917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KOIZUMI Kenji (40053342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TANAKA Masayuki (30573414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
20. AMAGAI Masayuki (90212563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SHIMIZU Hiroshi (00146672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NISHIKAWA Takeji (50051579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MINOSHIMA Shinsei (90181966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NAGAFUCHI Seiho (00150441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SAKAGUCHI Shimon (30280770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. KUROSAKA Daijirou (20215099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. SHIMAZU Motohide (70124948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. FUJITA Yoko (10328106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
29. Fujii Takuma (10218969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 雨宮隆介 (60626696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. 岩田卓 (30296652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. IWATA Takeshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKAYANAGI Atsushi 高柳 淳

高柳 淳 タカヤナギ アツシ

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Developments of A New Antibody Library and Antibody ChipsPrincipal Investigator

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抗体を利用した遺伝子導入法「ヒト型イムノジーン法」の開発Principal Investigator

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TAKAYANAGI Atsushi 高柳淳

高柳淳タカヤナギアツシ