matsuda noriyuki 松田憲之

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MATSUDA Noriyuki 松田憲之

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Researcher Number	10332272
Other IDs	https://orcid.org/0000-0001-8199-952X
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 教授 2025: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, プロジェクトリーダー 2025: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, プロジェクトリーダー
Affiliation (based on the past Project Information) *help	2022 – 2023: 東京医科歯科大学, 難治疾患研究所, 教授 2019 – 2021: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, プロジェクトリーダー 2018 – 2021: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, プロジェクトリーダー 2016: 東京都医学総合研究所, 生体分子先端研究分野, プロジェクトリーダー 2013 – 2016: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, プロジェクトリーダー … More 2015: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 副参事研究員 2013: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 副参事研究員 2012: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席研究員 2011: 財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席研究員 2010: 東京都臨床医学総合研究所, 研究員 2009: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員 2008 – 2009: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Functional biochemistry / Basic Section 44010:Cell biology-related Except Principal Investigator Biological Sciences / Cell biology / Neurology
Keywords	Principal Investigator ミトコンドリア / PINK1 / Parkin / パーキンソン病 / ユビキチン / リン酸化 / 加水分解酵素 / Thermal shift assay / メチルグリオキサール / グリオキサール … More / アルデヒド / 加水酵素 / 解毒 / ヒドロキシ酸 / オキソアルデヒド / DJ-1 / 再構成 / RING finger motif / MG53 / 細胞膜修復 … More Except Principal Investigator ユビキチン / オートファジー / マイトファジー / ミトコンドリア / ROCK / 核膜孔複合体 / T細胞 / PKD / ERK / PINK1 / キナーゼ / リン酸化 / プロテオーム / シグナル伝達 / ミトファジー / パーキンソン病 Less

Molecular mechanism and physiological role of mitophagy
- Principal Investigator
  
  Kanki Tomotake
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
Detoxification of aldehyde-conjugation as a new mechanism for preventing onset of Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  MATSUDA Noriyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
翻訳後修飾因子の翻訳後修飾：リン酸化ユビキチンの細胞内機能の解析Principal Investigator
- Principal Investigator
  
  松田憲之
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
PINK1の作動機構解明からミトコンドリアホメオスタシスと神経変性の核心に迫るPrincipal Investigator
- Principal Investigator
  
  松田憲之
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
In vitro reconstitution of Parkin-mediated mitochondria quality controlPrincipal Investigator
- Principal Investigator
  
  MATSUDA Noriyuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Identification and functional analysis of substrates of disease-associated protein kinases using multiple phosphoproteomic technologies
- Principal Investigator
  
  KOSAKO Hidetaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokushima
ユビキチン連結酵素PARKINを活性化するメカニズムPrincipal Investigator
- Principal Investigator
  
  松田憲之
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
パーキンソン病発症を予防するミトコンドリアストレス応答機構の解析Principal Investigator
- Principal Investigator
  
  松田憲之
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Collapse of mitochondrial quality control mediated by PINK1 and Parkin causes Parkinson diseasePrincipal Investigator
- Principal Investigator
  
  MATSUDA Noriyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Effects of mitophagy on cell death in Parkinson's disease model cells
- Principal Investigator
  
  SAIKI Shinji
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Juntendo University
Ubiquitylation involved in Parkinson disease and membrane repairPrincipal Investigator
- Principal Investigator
  
  MATSUDA Noriyuki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

[Journal Article] MARC-3, a membrane-associated ubiquitin ligase, is required for fast polyspermy block in Caenorhabditis elegans2024
- Author(s)
  Kawasaki Ichiro、Sugiura Kenta、Sasaki Taeko、Matsuda Noriyuki、Sato Miyuki、Sato Ken
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 792-792
- DOI
  10.1038/s41467-024-44928-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15097, KAKENHI-PROJECT-23KJ0291, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-23K21307
[Journal Article] Optineurin provides a mitophagy contact site for TBK1 activation2024
- Author(s)
  Yamano Koji、Sawada Momoha、Kikuchi Reika、Nagataki Kafu、Kojima Waka、Endo Ryu、Kinefuchi Hiroki、Sugihara Atsushi、Fujino Tomoshige、Watanabe Aiko、Tanaka Keiji、Hayashi Gosuke、Murakami Hiroshi、Matsuda Noriyuki
- Journal Title
  
  The EMBO Journal
  
  Volume: 43 Issue: 5 Pages: 754-779
- DOI
  10.1038/s44318-024-00036-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05712, KAKENHI-WRAPUP-23H05424, KAKENHI-ORGANIZER-23H04917, KAKENHI-PLANNED-23H04923, KAKENHI-PROJECT-22H00419, KAKENHI-PROJECT-23K23841
[Journal Article] TIM23 facilitates PINK1 activation by safeguarding against OMA1-mediated degradation in damaged mitochondria2023
- Author(s)
  Shiori Akabane, Kiyona Watanabe, Hidetaka Kosako, Shun-ichi Yamashita, Kohei Nishino, Masahiro Kato, Shiori Sekine, Tomotake Kanki, Noriyuki Matsuda, Toshiya Endo, Toshihiko Oka
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 5 Pages: 112454-112454
- DOI
  10.1016/j.celrep.2023.112454
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03257, KAKENHI-PROJECT-22K15107, KAKENHI-PROJECT-20K06628, KAKENHI-PLANNED-20H05929, KAKENHI-PROJECT-20H05689, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-23K23878, KAKENHI-PROJECT-23K27171
[Journal Article] Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid-liquid phase separation-based method2023
- Author(s)
  Hayashida Ryota、Kikuchi Reika、Imai Kenichiro、Kojima Waka、Yamada Tatsuya、Iijima Miho、Sesaki Hiromi、Tanaka Keiji、Matsuda Noriyuki、Yamano Koji
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 2 Pages: 102822-102822
- DOI
  10.1016/j.jbc.2022.102822
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00419, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-23K23841
[Journal Article] Unfolding is the driving force for mitochondrial import and degradation of the Parkinson's disease-related protein DJ-12021
- Author(s)
  Queliconi BB, Kojima W, Kimura M, Imai K, Udagawa C, Motono C, Hirokawa T, Tashiro S, Caaveiro JMM, Tsumoto K, Yamano K, Tanaka K, Matsuda N
- Journal Title
  
  J Cell Sci
  
  Volume: 134 Issue: 22 Pages: 1-1
- DOI
  10.1242/jcs.258653
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11543, KAKENHI-PROJECT-18H02443, KAKENHI-PLANNED-18H05500, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-20H02531
[Journal Article] Molecular mechanisms and physiological functions of mitophagy2021
- Author(s)
  Onishi Mashun、Yamano Koji、Sato Miyuki、Matsuda Noriyuki、Okamoto Koji
- Journal Title
  
  The EMBO Journal
  
  Volume: 40 Issue: 3 Pages: 1-1
- DOI
  10.15252/embj.2020104705
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05500, KAKENHI-PLANNED-19H05712, KAKENHI-PUBLICLY-20H05324, KAKENHI-PROJECT-18H02435, KAKENHI-PROJECT-19F19816, KAKENHI-PROJECT-18K06237, KAKENHI-PROJECT-19H03222
[Journal Article] Loss of peptide: N -glycanase causes proteasome dysfunction mediated by a sugar-recognizing ubiquitin ligase2021
- Author(s)
  Yoshida Yukiko、Asahina Makoto、Murakami Arisa、Kawawaki Junko、Yoshida Meari、Fujinawa Reiko、Iwai Kazuhiro、Tozawa Ryuichi、Matsuda Noriyuki、Tanaka Keiji、Suzuki Tadashi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 27
- DOI
  10.1073/pnas.2102902118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02443, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05499, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-17H06174, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-19H02926
[Journal Article] Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy2021
- Author(s)
  Kojima W, Yamano K, Kosako H, Imai K, Kikuchi R, Tanaka K, Matsuda N
- Journal Title
  
  Autophagy
  
  Volume: - Issue: 8 Pages: 1-26
- DOI
  10.1080/15548627.2021.1874133
- NAID
  120007174412
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11543, KAKENHI-PROJECT-20K06628, KAKENHI-PUBLICLY-19H04966, KAKENHI-PROJECT-18K06237, KAKENHI-PROJECT-18H02443, KAKENHI-PLANNED-18H05500, KAKENHI-PLANNED-19H05712
[Journal Article] Cleaved PGAM5 dephosphorylates nuclear serine/arginine-rich proteins during mitophagy.2021
- Author(s)
  Baba, T., Tanimura, S., Yamaguchi, A., Horikawa, K., Yokozeki, M., Hachiya, S., Iemura, S., Natsume, T., Matsuda, N. and Takeda, K.
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  
  Volume: 11868 Issue: 7 Pages: 119045-119045
- DOI
  10.1016/j.bbamcr.2021.119045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07032, KAKENHI-PROJECT-18H02443, KAKENHI-PLANNED-19H05712
[Journal Article] Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase2021
- Author(s)
  Fukuda Tomoyuki、Sofyantoro Fajar、Tai Yen Teng、Chia Kim Hou、Matsuda Takato、Murase Takaaki、Morozumi Yuichi、Tatebe Hisashi、Kanki Tomotake、Shiozaki Kazuhiro
- Journal Title
  
  eLife
  
  Volume: 10
- DOI
  10.7554/elife.60969
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06564, KAKENHI-PROJECT-20K06552, KAKENHI-PROJECT-19K22419, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-19H03224
[Journal Article] Critical role of mitochondrial ubiquitination and the OPTN?ATG9A axis in mitophagy2020
- Author(s)
  Yamano Koji、Kikuchi Reika、Kojima Waka、Hayashida Ryota、Koyano Fumika、Kawawaki Junko、Shoda Takuji、Demizu Yosuke、Naito Mikihiko、Tanaka Keiji、Matsuda Noriyuki
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 219 Issue: 9 Pages: 1-23
- DOI
  10.1083/jcb.201912144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-19K07009, KAKENHI-PLANNED-18H05500, KAKENHI-PLANNED-18H05502, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-18K06237, KAKENHI-ORGANIZER-18H05497
[Journal Article] Two sides of a coin: Physiological significance and molecular mechanisms for damage-induced mitochondrial localization of PINK1 and Parkin2020
- Author(s)
  Matsuda Noriyuki、Yamano Koji
- Journal Title
  
  Neuroscience Research
  
  Volume: in press Pages: 16-24
- DOI
  10.1016/j.neures.2020.03.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05500, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-18K06237
[Journal Article] PINK1/Parkin 依存性マイトファジーにおける Parkin 活性化の分子機構2019
- Author(s)
  松田憲之
- Journal Title
  
  生化学
  
  Volume: 91(5) Pages: 626-633
- Data Source
  KAKENHI-PROJECT-18H02443
[Journal Article] Cleaved PGAM5 is released from mitochondria depending on proteasome-mediated rupture of the outer mitochondrial membrane during mitophagy2019
- Author(s)
  Yamaguchi Ayane、Ishikawa Hayate、Furuoka Mana、Yokozeki Masashi、Matsuda Noriyuki、Tanimura Susumu、Takeda Kohsuke
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 165 Issue: 1 Pages: 19-25
- DOI
  10.1093/jb/mvy077
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05511, KAKENHI-PROJECT-18H02443, KAKENHI-PROJECT-16K08238, KAKENHI-PROJECT-17K19768
[Journal Article] Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes2019
- Author(s)
  Koyano Fumika、Yamano Koji、Kosako Hidetaka、Kimura Yoko、Kimura Mayumi、Fujiki Yukio、Tanaka Keiji、Matsuda Noriyuki
- Journal Title
  
  EMBO reports
  
  Volume: 20 Issue: 12
- DOI
  10.15252/embr.201947728
- NAID
  120006942558
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08635, KAKENHI-PROJECT-18K06237, KAKENHI-PROJECT-18K14708, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-17H03675, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-18H02443
[Journal Article] 細胞の恒常性維持を担う動的なユビキチン修飾2019
- Author(s)
  松田憲之
- Journal Title
  
  実験医学（増刊号）
  
  Volume: 37(7) Pages: 34-46
- Data Source
  KAKENHI-PROJECT-18H02443
[Journal Article] Parkin recruitment to impaired mitochondria for nonselective ubiquitylation is facilitated by MITOL2019
- Author(s)
  Koyano Fumika、Yamano Koji、Kosako Hidetaka、Tanaka Keiji、Matsuda Noriyuki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 26 Pages: 10300-10314
- DOI
  10.1074/jbc.ra118.006302
- NAID
  120006959752
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08635, KAKENHI-PROJECT-18K06237, KAKENHI-PROJECT-18K14708, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-18H02443
[Journal Article] Endosomal Rab cycles regulate Parkin-mediated mitophagy.2018
- Author(s)
  Yamano K, Wang C, Sarraf SA, Münch C, Kikuchi R, Noda NN, Hizukuri Y, Kanemaki MT, Harper W, Tanaka K, Matsuda N, Youle RJ.
- Journal Title
  
  eLife
  
  Volume: 7
- DOI
  10.7554/elife.31326
- NAID
  120006457172
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15091, KAKENHI-PLANNED-25111004, KAKENHI-PROJECT-16K15095, KAKENHI-PROJECT-16K18545, KAKENHI-PROJECT-26000014, KAKENHI-PUBLICLY-18H04719, KAKENHI-PROJECT-18H02170, KAKENHI-PROJECT-18H02443
[Journal Article] パーキンソン病の病因 2-3-1 “タンパク質・オルガネラ・アルデヒド分解系”2018
- Author(s)
  松田憲之
- Journal Title
  
  日本臨牀
  
  Volume: 76(4) Pages: 156-161
- Data Source
  KAKENHI-PROJECT-18H02443
[Journal Article] マイトファジー：PINK1とParkinによるミトコンドリア蛋白質の品質管理2018
- Author(s)
  松田憲之、山野晃史
- Journal Title
  
  医学のあゆみ
  
  Volume: 267(13) Pages: 1056-1062
- Data Source
  KAKENHI-PROJECT-18H02443
[Journal Article] Discovery and Optimization of Inhibitors of the Parkinson’s Disease Associated Protein DJ-12018
- Author(s)
  Tashiro Shinya、Caaveiro Jose M. M.、Nakakido Makoto、Tanabe Aki、Nagatoishi Satoru、Tamura Yasushi、Matsuda Noriyuki、Liu Dali、Hoang Quyen Q.、Tsumoto Kouhei
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 13 Issue: 9 Pages: 2783-2793
- DOI
  10.1021/acschembio.8b00701
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-18H02443, KAKENHI-PROJECT-17J07322, KAKENHI-PROJECT-17K19338, KAKENHI-PROJECT-15H05705, KAKENHI-PROJECT-16H04710
[Journal Article] ユビキチンリン酸化2018
- Author(s)
  松田憲之
- Journal Title
  
  生体の科学
  
  Volume: 69(5) Pages: 456-457
- Data Source
  KAKENHI-PROJECT-18H02443
[Journal Article] Structural insights into ubiquitin phosphorylation by PINK12018
- Author(s)
  Okatsu Kei、Sato Yusuke、Yamano Koji、Matsuda Noriyuki、Negishi Lumi、Takahashi Akiko、Yamagata Atsushi、Goto-Ito Sakurako、Mishima Masaki、Ito Yutaka、Oka Toshihiko、Tanaka Keiji、Fukai Shuya
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 10382-10382
- DOI
  10.1038/s41598-018-28656-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05887, KAKENHI-PUBLICLY-17H05888, KAKENHI-PLANNED-18H05501, KAKENHI-PROJECT-16H04749, KAKENHI-PROJECT-16H04750, KAKENHI-PROJECT-17H03676, KAKENHI-PROJECT-18H02443, KAKENHI-PROJECT-26000014
[Journal Article] Phospo-ubiquitin: Upending the PINK-Parkin-ubiquitin cascade.2016
- Author(s)
  Matsuda, N.
- Journal Title
  
  J. Biochemistry
  
  Volume: 159 Issue: 4 Pages: 379-385
- DOI
  10.1093/jb/mvv125
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01196
[Journal Article] Constitutive activation of PINK1 leads to proteasome-mediated and non-apoptotic cell death independently of mitochondrial autophagy2016
- Author(s)
  Akabane, S., Matsuzaki, K., Yamashita, S-I, Arai, K., Okatsu, K., Kanki, T., Matsuda, N., and Oka, T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291 Issue: 31 Pages: 16162-16174
- DOI
  10.1074/jbc.m116.714923
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01196, KAKENHI-PUBLICLY-16H01198, KAKENHI-PUBLICLY-16H01384, KAKENHI-PROJECT-26291039, KAKENHI-PROJECT-26440106, KAKENHI-PROJECT-15K18501
[Journal Article] The ubiquitin signal and autophagy : an orchestrated dance leading to mitochondrial degradation2016
- Author(s)
  Koji Yamano, K., Matsuda, N., and Tanaka, K.
- Journal Title
  
  EMBO Rep.
  
  Volume: 17 Issue: 3 Pages: 300-3016
- DOI
  10.15252/embr.201541486
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000014, KAKENHI-PUBLICLY-15H01196
[Journal Article] ミトコンドリアクオリティコントロールとパーキンソン病 - 特に DJ-1 に着目して -2016
- Author(s)
  小島和華、松田憲之
- Journal Title
  
  脳21
  
  Volume: 19 Pages: 13-20
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01196
[Journal Article] パーキンソン病と闘うユビキチンシステム2016
- Author(s)
  松田憲之
- Journal Title
  
  医学のあゆみ
  
  Volume: 256 Pages: 874-879
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01196
[Journal Article] Unexpected mitochondrial matrix localization of Parkinson's disease-related DJ-1 mutants but not wild type DJ-1.2016
- Author(s)
  Kojima, W., Kujuro, Y., Okatsu, K., Bruno, Q., Koyano, F., Kimura, M., Yamano, K., Tanaka, K., and Matsuda, N.
- Journal Title
  
  Genes to Cells
  
  Volume: 21 Issue: 7 Pages: 772-788
- DOI
  10.1111/gtc.12382
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01196, KAKENHI-PROJECT-26000014
[Journal Article] Phosphorylated ubiquitin chain is the genuine Parkin receptor.2015
- Author(s)
  K. Okatsu, F. Koyano, M. Kimura, H. Kosako, Y. Saeki, K. Tanaka and N. Matsuda
- Journal Title
  
  The Journal of Cell Biology
  
  Volume: 209 Issue: 1 Pages: 111-128
- DOI
  10.1083/jcb.201410050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-15K19037, KAKENHI-PUBLICLY-15H01196, KAKENHI-PLANNED-24112008, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-26000014
[Journal Article] Unconventional PINK1 localization mechanism to the outer membrane of depolarized mitochondria drives Parkin recruitment2015
- Author(s)
  Okatsu, K., Kimura, M., Oka, T., Tanaka, K., and Matsuda N.
- Journal Title
  
  J Cell Sci
  
  Volume: 128 Pages: 964-978
- DOI
  10.1242/jcs.161000
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-26440106, KAKENHI-PUBLICLY-15H01196, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26650042
[Journal Article] Site-specific Interaction Mapping of Phosphorylated Ubiquitin to Uncover Parkin Activation.2015
- Author(s)
  Koji Yamano, Bruno B. Queliconi, Fumika Koyano, Yasushi Saeki, Takatsugu Hirokawa, Keiji Tanaka§,and Noriyuki Matsuda
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 290 Issue: 42 Pages: 25199-25211
- DOI
  10.1074/jbc.m115.671446
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19037, KAKENHI-PUBLICLY-15H01196, KAKENHI-PLANNED-24112008, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-26000014
[Journal Article] 遺伝性パーキンソン病関連分子 PINK1 によってリン酸化されたユビキチンが Parkin を活性化する2014
- Author(s)
  松田憲之
- Journal Title
  
  細胞工学
  
  Volume: 33 Pages: 974-976
- Data Source
  KAKENHI-PUBLICLY-25112522
[Journal Article] Ubiquitin is phosphorylated by PINK1 to activate parkin.2014
- Author(s)
  Koyano, F., Okatsu, K., Kosako, H., Tamura, Y., Go, E., Kimura, M., Kimura, Y., Tsuchiya, H., Yoshihara, H., Hirokawa, T., Endo, T., Fon. E. A., Trempe, J. F., Saeki, Y., Tanaka, K., and Matsuda, N.
- Journal Title
  
  Nature
  
  Volume: 510(in press) Issue: 7503 Pages: 162-166
- DOI
  10.1038/nature13392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23570231, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-24657072, KAKENHI-PUBLICLY-25112522, KAKENHI-PROJECT-25870311, KAKENHI-PROJECT-26000014, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26440070, KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-22227003
[Journal Article] 遺伝性パーキンソン病関連分子 PINK1 によってリン酸化されたユビキチンが Parkin を活性化する2014
- Author(s)
  松田憲之
- Journal Title
  
  細胞工学
  
  Volume: 33 Pages: 974-976
- Data Source
  KAKENHI-PUBLICLY-26111729
[Journal Article] 遺伝性パーキンソン病関連分子 PINK1 によってリン酸化されたユビキチンが Parkin を活性化する2014
- Author(s)
  松田憲之
- Journal Title
  
  細胞工学
  
  Volume: 33 Pages: 974-976
- Data Source
  KAKENHI-PROJECT-26650042
[Journal Article] リン酸化ユビキチンは新しいパーキンソン病発症の抑制因子である2014
- Author(s)
  小谷野史香、松田憲之
- Journal Title
  
  実験医学
  
  Volume: 32 Pages: 2616-2620
- Data Source
  KAKENHI-PUBLICLY-26111729
[Journal Article] リン酸化ユビキチンは新しいパーキンソン病発症の抑制因子である2014
- Author(s)
  小谷野史香、松田憲之
- Journal Title
  
  実験医学
  
  Volume: 32 Pages: 2616-2620
- Data Source
  KAKENHI-PUBLICLY-25112522
[Journal Article] リン酸化ユビキチンは新しいパーキンソン病発症の抑制因子である2014
- Author(s)
  小谷野史香、松田憲之
- Journal Title
  
  実験医学
  
  Volume: 32 Pages: 2616-2620
- Data Source
  KAKENHI-PROJECT-26650042
[Journal Article] A dimeric PINK1-containing complex on depolarized mitochondria stimulates Parkin recruitment2013
- Author(s)
  Kei Okatsu, Midori Uno, Fumika Koyano, Etsu Go, Mayumi kimura, Toshihiko Oka, Keiji Tanaka, Noriyuki Matsuda
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288 Issue: 51 Pages: 36372-84
- DOI
  10.1074/jbc.m113.509653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06061, KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23570232, KAKENHI-PROJECT-23687018, KAKENHI-PUBLICLY-24111557, KAKENHI-PUBLICLY-25112522
[Journal Article] Parkin catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation2013
- Author(s)
  Masahiro Iguchi, Yuki Kujuro, Kei Okatsu, Fumika Koyano, Hidetaka Kosako, Mayumi Kimura, Norihiro Suzuki, Shinichiro Uchiyama, Keiji Tanaka, Noriyuki Matsuda
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288 Issue: 30 Pages: 22019-32
- DOI
  10.1074/jbc.m113.467530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06061, KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23570231, KAKENHI-PROJECT-23687018, KAKENHI-PUBLICLY-24111557, KAKENHI-PUBLICLY-25112522, KAKENHI-PROJECT-25860721
[Journal Article] The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential also occur in primary neurons2013
- Author(s)
  Fumika Koyano, Kei Okatsu, Shinsuke Ishigaki, Yusuke Fujioka, Mayumi Kimura, Keiji Tanaka, Noriyuki Matsuda
- Journal Title
  
  Genes to Cells
  
  Volume: 18 Issue: 8 Pages: 672-81
- DOI
  10.1111/gtc.12066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06061, KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23687018, KAKENHI-PUBLICLY-24111557, KAKENHI-PUBLICLY-25112522
[Journal Article] 遺伝性パーキンソン病関連分子PINK1は自己リン酸化を介して「ミトコンドリア異常」シグナルをParkinに伝達する細胞工学2012
- Author(s)
  松田憲之
- Journal Title
  
  Hot Press(秀潤社)
  
  Volume: Vol.31, No.12 Pages: 1374-75
- Data Source
  KAKENHI-PROJECT-23687018
[Journal Article] Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase2012
- Author(s)
  Okatsu, K., Iemura, S-I., Koyano, F., Go, E., Kimura, M., Natsume, T., Tanaka, K., and Matsuda, N
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 428 (1) Issue: 1 Pages: 197-202
- DOI
  10.1016/j.bbrc.2012.10.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23687018, KAKENHI-PUBLICLY-24111557
[Journal Article] PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria2012
- Author(s)
  尾勝圭
- Journal Title
  
  Nature Communications
  
  Volume: 3 Issue: 1 Pages: 1016-1016
- DOI
  10.1038/ncomms2016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06061, KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-22370042, KAKENHI-PROJECT-22370071, KAKENHI-PROJECT-23570231, KAKENHI-PROJECT-23570232, KAKENHI-PROJECT-23687018, KAKENHI-PROJECT-24657138, KAKENHI-PROJECT-24790896, KAKENHI-PLANNED-23111003, KAKENHI-PUBLICLY-23129506, KAKENHI-PUBLICLY-24111557, KAKENHI-PUBLICLY-24113717
[Journal Article] Parkin mediates apparent E2-independent monoubiquitination in vitro and contains an intrinsic activity that catalyzes polyubiquitination2011
- Author(s)
  Chew, KCM*., Matsuda, M*., Saisho, K., Lim, GGY., Chai, C., Tan, HM., Tanaka, K., Lim, K-L.(*equally contribution)
- Journal Title
  
  PloS ONE.
  
  Volume: 6(5) Issue: 5 Pages: e19720-e19720
- DOI
  10.1371/journal.pone.0019720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23687018
[Journal Article] PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.2010
- Author(s)
  Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier CA, Sou YS, Saiki S, Kawajiri S, Sato F, Kimura M, Komatsu M, Hattori N, Tanaka K.
- Journal Title
  
  J Cell Biol 189
  
  Pages: 211-221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790853
[Journal Article] Clement A Gautier, Yu-shin Sou, Shinji Saiki, Sumihiro Kawajiri, Fumiaki Sato, Mayumi Kimura, Masaaki Komatsu, Nobutaka Hattori and Keiji Tanaka2010
- Author(s)
  Noriyuki Matsuda, Shigeto Sato, Kahori Shiba, Kei Okatsu, Keiko Saisho
- Journal Title
  
  PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. Journal of Cell Biology 189(2)
  
  Pages: 211-221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770112
[Journal Article] PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.2010
- Author(s)
  Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier CA, Sou YS, Saiki S, Kawajiri S, Sato F, Kimura M, Komatsu M, Hattori N, Tanaka K.
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 189 Pages: 211-221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790853
[Journal Article] PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy.2010
- Author(s)
  Noriyuki Matsuda, Keiji Tanaka
- Journal Title
  
  Journal of Cell Biology 189(2)
  
  Pages: 211-221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770112
[Journal Article] MG53 nucleates assembly of cell membrane repair machinery.2009
- Author(s)
  Chuanxi Cai, Haruko Masumiya, Noah Weisleder, Noriyuki Matsuda, Miyuki Nishi, Moonsun Hwang, Jae-Kyun Ko, Peihui Lin, Angela Thornton, Xiaoli Zhao, Zui Panl, Shinji Komazaki, Marco Brotto, Hiroshi Takeshima and Jianjie Ma
- Journal Title
  
  Nature Cell Biology 11(1)
  
  Pages: 56-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770112
[Journal Article] MG53 nucleates assembly of cell membrane repair machinery.2009
- Author(s)
  Chuanxi Cai, Haruko Masumiya, Noah Weisleder, Noriyuki Matsuda, Miyuki Nishi, Moonsun Hwang, Jae-Kyun Ko, Peihui Lin, Angela Thornton, Xiaoli Zhao, Zui Pan1, Shinji Komazaki, Marco Brotto, Hiroshi Takeshima, Jianjie Ma
- Journal Title
  
  Nat Cell Biol 11(1)
  
  Pages: 56-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770112
[Patent] パーキンソン病のバイオマーカーおよびその利用2014
- Inventor(s)
  松田憲之、小谷野史香、尾勝圭、呉越、木村まゆみ、佐伯泰
- Industrial Property Rights Holder
  松田憲之、小谷野史香、尾勝圭、呉越、木村まゆみ、佐伯泰
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-18
- Data Source
  KAKENHI-PUBLICLY-24111557
[Patent] パーキンソン病のバイオマーカーおよびその利用2014
- Inventor(s)
  松田憲之、小谷野史香、尾勝圭、呉越、木村まゆみ、佐伯泰
- Industrial Property Rights Holder
  松田憲之、小谷野史香、尾勝圭、呉越、木村まゆみ、佐伯泰
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-18
- Data Source
  KAKENHI-PROJECT-23687018
[Patent] パーキンソン病のバイオマーカーおよびその利用2014
- Inventor(s)
  松田憲之、小谷野史香、尾勝圭、呉越、木村まゆみ、佐伯泰
- Industrial Property Rights Holder
  松田憲之、小谷野史香、尾勝圭、呉越、木村まゆみ、佐伯泰
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-18
- Data Source
  KAKENHI-PUBLICLY-25112522
[Presentation] パーキンソン病発症に関与するミトコンドリア品質管理と細胞死2023
- Author(s)
  松田憲之
- Organizer
  第３１回日本 Cell Death 学会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05712
[Presentation] PINK1-PARKIN介在性マイトファジー2023
- Author(s)
  松田憲之
- Organizer
  第９回ガンと代謝研究会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05712
[Presentation] FAF2-p97/VCP complex suppresses pexophagy in a ubiquitylation-dependent fashion2022
- Author(s)
  Noriyuki Matsuda, and Fumika Koyano
- Organizer
  The 10th International Symposium on Autophagy
- Data Source
  KAKENHI-PLANNED-19H05712
[Presentation] ミトコンドリアを軸にしたオートファジー制御因子の機能解析2022
- Author(s)
  小島和華, 松田憲之, 山野晃史
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05712
[Presentation] DJ-1のアンフォールディングがミトコンドリア移行と分解を引き起こす2021
- Author(s)
  松田憲之
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] 遺伝性パーキンソン病関連タンパク質DJ-1がミトコンドリアに移行する仕組み2021
- Author(s)
  松田憲之
- Organizer
  第20回日本ミトコンドリア学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] 損傷ミトコンドリア近傍で Parkin が de novo に隔離膜を形成する分子メカニズム2021
- Author(s)
  松田憲之
- Organizer
  第43回神経組織培養研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] ミトコンドリア-リソソーム連携の破綻とパーキンソン病2019
- Author(s)
  松田憲之
- Organizer
  Neuro 2019 (第42回日本神経科学大会第62回日本神経化学会大会)
- Invited
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] PINK1, Parkin, DJ-1はミトコンドリア品質管理やアルデヒド解毒を介してパーキンソン病を防止する2019
- Author(s)
  松田憲之
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] New role for PINK1/Parkin-mediated ubiquitylation2019
- Author(s)
  Noriyuki Matsuda
- Organizer
  Singapore Mitochondrial Mini-Symposium 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] PINK1, Parkin and the ubiquitin system in TP52019
- Author(s)
  Noriyuki Matsuda
- Organizer
  5th WPC (5th World Parkinson Congress)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] New role for PINK1/Parkin-mediated ubiquitylation2019
- Author(s)
  Noriyuki Matsuda
- Organizer
  Singapore Mitochondrial Mini-Symposium 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05712
[Presentation] PINK1, Parkin and the ubiquitin system2019
- Author(s)
  Noriyuki Matsuda
- Organizer
  5th World Parkinson Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05712
[Presentation] 遺伝性パーキンソン病の原因遺伝子産物からミトコンドリア品質管理を考える2019
- Author(s)
  松田憲之
- Organizer
  第二回三融会・武田神経科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] Mitochondria quality control elucidated from Parkinson's disease2018
- Author(s)
  Noriyuki Matsuda
- Organizer
  Keystone Symposia, joint symposium of Mitochondrial Biology (Z1) and Selective Autophagy (Z2)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] 生化学・細胞・構造の視点から見たPINK1とParkinによるミトコンドリア品質管理2018
- Author(s)
  松田憲之
- Organizer
  第１８回日本ミトコンドリア学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] マイトファジーの破綻と遺伝性パーキンソン病2018
- Author(s)
  松田憲之
- Organizer
  千里ライフサイエンスセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] How PINK1 and Parkin catalyze mitochondrial ubiquitylation and the ubiquitin chain prevents Parkinson’s disease2018
- Author(s)
  Noriyuki Matsuda
- Organizer
  第４１回日本神経科学大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] リン酸化ユビキチンの発見とマイトファジー制御2018
- Author(s)
  松田憲之
- Organizer
  第59回日本植物生理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02443
[Presentation] パーキンソン病とミトコンドリア分解2016
- Author(s)
  松田憲之
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01196
[Presentation] ミトコンドリア品質管理マシナリーからパーキンソン病の発症機構を明らかにする2016
- Author(s)
  松田憲之
- Organizer
  第54回日本生物物理学会年会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01196
[Presentation] 修飾酵素と修飾因子のヒエラルキーを逆転させるリン酸化2016
- Author(s)
  松田憲之
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01196
[Presentation] PINK1/Parkin-catalyzed ubiquitylation prevents Parkinson's disease via mitochondrial quality control2016
- Author(s)
  Matsuda N
- Organizer
  KSBMB 2016
- Place of Presentation
  COEX, Seoul, Korea
- Year and Date
  2016-05-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01196
[Presentation] Molecular mechanisms underlying PINK1 and Parkin localization on damaged mitochondria2015
- Author(s)
  Noriyuki Matsuda
- Organizer
  Mitochondrial quality control and neurodegenerative diseases held at the Fondation des Treilles
- Place of Presentation
  Nice, France
- Year and Date
  2015-05-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26650042
[Presentation] Molecular mechanisms underlying PINK1 and Parkin localization on damaged mitochondria.2015
- Author(s)
  Noriyuki Matsuda
- Organizer
  “Mitochondrial quality control and neurodegenerative diseases” held at the Fondation des Treilles
- Place of Presentation
  Nice, France
- Year and Date
  2015-05-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01196
[Presentation] Molecular mechanisms underlying PINK1 and Parkin localization on damaged mitochondria.2015
- Author(s)
  Noriyuki Matsuda
- Organizer
  "Mitochondrial quality control and neurodegenerative diseases” held at the Fondation des Treilles
- Place of Presentation
  Nice, France
- Year and Date
  2015-05-04
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26111729
[Presentation] Identification of the Genuine Substrate of PINK1 that Activates Parkin2014
- Author(s)
  Noriyuki Matsuda
- Organizer
  Keystone Symposium, Mitochondrial Dynamics and Physiology (Q5)
- Place of Presentation
  Santa Fe Community Convention Center, Santa Fe, New Mexico, USA
- Invited
- Data Source
  KAKENHI-PROJECT-23687018
[Presentation] Identification of the Genuine Substrate of PINK1 that Activates Parkin2014
- Author(s)
  Noriyuki Matsuda
- Organizer
  Keystone Symposium, Mitochondrial Dynamics and Physiology (Q5)
- Place of Presentation
  Santa Fe Community Convention Center, Santa Fe, New Mexico, USA
- Invited
- Data Source
  KAKENHI-PUBLICLY-24111557
[Presentation] Identification of the Genuine Substrate of PINK1 that Activates Parkin2014
- Author(s)
  Noriyuki Matsuda
- Organizer
  Keystone Symposium, Mitochondrial Dynamics and Physiology (Q5)
- Place of Presentation
  Santa Fe Community Convention Center, Santa Fe, New Mexico, USA
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112522
[Presentation] 遺伝性パーキンソン病の関連因子 PINK1 と Parkin がミトコンドリア異常をモニターする仕組み2013
- Author(s)
  松田憲之
- Organizer
  第86回日本生化学会大会シンポジウム「ミトコンドリアワールド：エネルギー生産から生体内環境保全まで」
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PUBLICLY-24111557
[Presentation] Parkin catalyzes ubiquitylation on damaged mitochondria via a (ubiquitin-ester)-transfer rather than an E2-recruitment2013
- Author(s)
  Noriyuki Matsuda and Keiji Tanaka
- Organizer
  International Symposium on Mitochondria 2013
- Place of Presentation
  Roppongi Hills
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112522
[Presentation] 遺伝性パーキンソン病の関連因子 PINK1 と Parkin がミトコンドリア異常をモニターする仕組み2013
- Author(s)
  松田憲之
- Organizer
  第86回日本生化学会大会シンポジウム「ミトコンドリアワールド：エネルギー生産から生体内環境保全まで」
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23687018
[Presentation] 遺伝性パーキンソン病の関連因子 PINK1 と Parkin がミトコンドリア異常をモニターする仕組み2013
- Author(s)
  松田憲之
- Organizer
  第86回日本生化学会大会シンポジウム「ミトコンドリアワールド：エネルギー生産から生体内環境保全まで」
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112522
[Presentation] Parkin catalyzes ubiquitylation on damaged mitochondria via a (ubiquitin-ester)-transfer rather than an E2-recruitment2013
- Author(s)
  Noriyuki Matsuda and Keiji Tanaka
- Organizer
  International Symposium on Mitochondria 2013
- Place of Presentation
  Roppongi Hills
- Invited
- Data Source
  KAKENHI-PROJECT-23687018
[Presentation] Parkin catalyzes ubiquitylation on damaged mitochondria via a (ubiquitin-ester)-transfer rather than an E2-recruitment2013
- Author(s)
  Noriyuki Matsuda and Keiji Tanaka
- Organizer
  International Symposium on Mitochondria 2013
- Place of Presentation
  東京（Roppongi Hills）
- Invited
- Data Source
  KAKENHI-PUBLICLY-24111557
[Presentation] 家族性パーキンソン病の責任遺伝子産物 Parkin のE3 酵素活性はミトコンドリアによって制御される2012
- Author(s)
  松田憲之
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡（福岡国際会議場）
- Year and Date
  2012-12-14
- Invited
- Data Source
  KAKENHI-PUBLICLY-24111557
[Presentation] PINK1 による「ミトコンドリア異常」シグナル：膜電位の低下は PINK1 の自己リン酸化を介して伝達される2012
- Author(s)
  松田憲之
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋（名古屋国際会議場）
- Invited
- Data Source
  KAKENHI-PROJECT-23687018
[Presentation] 家族性パーキンソン病の責任遺伝子産物 Parkin のE3 酵素活性はミトコンドリアによって制御される2012
- Author(s)
  松田憲之
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡（福岡国際会議場）
- Invited
- Data Source
  KAKENHI-PROJECT-23687018
[Presentation] PINK1 による「ミトコンドリア異常」シグナル：膜電位の低下は PINK1 の自己リン酸化を介して伝達される2012
- Author(s)
  松田憲之
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋（名古屋国際会議場）
- Year and Date
  2012-09-18
- Invited
- Data Source
  KAKENHI-PUBLICLY-24111557
[Presentation] PINK1による「ミトコンドリア異常」シグナル:膜電位の低下はPINK1の自己リン酸化を介して伝達されるAutophosphorylation of PINK1 upon the dissipation of mitochondrial membrane potential is essential for recruitment of Parkin to damaged mitochondria2012
- Author(s)
  松田憲之,尾勝圭,岡敏彦,小迫英尊,田中啓二
- Organizer
  第35回日本神経科学大会inシンポジウム「神経変性機序解明に向けた新たな展開」
- Place of Presentation
  名古屋(名古屋国際会議場)
- Invited
- Data Source
  KAKENHI-PROJECT-23687018
[Presentation] Phosphorylation and activation of PINK1 in response to dissipation of mitochondrial membrae potential recruits cytosolic Parkin to damaged mitochondria for selective clearance2011
- Author(s)
  松田憲之, 尾勝圭, 岡敏彦, 田中啓二
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23687018
[Presentation] 「ストレスシグナル研究の最前線」ミトコンドリア異常を伝えるPINK1シグナル(PINK1 as a signal component of damaged mitochondria)2011
- Author(s)
  松田憲之,尾勝圭,田中啓二
- Organizer
  第84回日本生化学会大会シンポジウム2S2a
- Place of Presentation
  京都(国立京都国際会館)
- Invited
- Data Source
  KAKENHI-PROJECT-23687018
[Presentation] ミトコンドリア異常を伝えるPINK1シグナル2011
- Author(s)
  松田憲之, 尾勝圭, 田中啓二
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都(国立京都国際会館)(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23687018
[Presentation] ミトコンドリアから見た神経変性機序パーキンソン病を例に2011
- Author(s)
  松田憲之
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋(名古屋国際会議場)(招待講演)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23687018
[Presentation] PINK1 recruits Parkin to damaged mitochondria for degradation.2010
- Author(s)
  Noriyuki Matsuda
- Organizer
  The 2nd International Symposium of NCRC "Mitochondria and Autophagy in Neurodegenerative Diseases"
- Place of Presentation
  Kyung Hee University, Seoul, Korea (招待講演).
- Year and Date
  2010-02-08
- Data Source
  KAKENHI-PROJECT-20770112
[Presentation] PINK1 recruits Parkin to damaged mitochondria for degradation2010
- Author(s)
  Noriyuki Matsuda
- Organizer
  The 2nd International Symposium of NCRC
- Place of Presentation
  韓国・ソウル市・Kyung Hee University
- Year and Date
  2010-02-08
- Data Source
  KAKENHI-PROJECT-20770112
[Presentation] Parkin is retrieved from the cytoplasm to depolarized mitochondria, and triggers its degradation.2009
- Author(s)
  Noriyuki Matsuda
- Organizer
  5th International Symposium on Autophagy
- Place of Presentation
  滋賀県・大津市
- Data Source
  KAKENHI-PROJECT-20770112
[Presentation] パーキンソン病は膜電位を失ったミトコンドリアのQuality control diseaseである.2009
- Author(s)
  松田憲之, 田中啓二
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20770112
[Presentation] Parkin is retrieved from the cytoplasm to depolarized mitochondria, and triggers its degradation.2009
- Author(s)
  Noriyuki Matsuda
- Organizer
  5th International Symposium on Autophagy
- Place of Presentation
  Otsu, Shiga, Japan
- Data Source
  KAKENHI-PROJECT-20770112
[Presentation] パーキンソン病は膜電位を失ったミトコンドリアのQuality control diseaseである2009
- Author(s)
  松田憲之, 田中啓二
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20770112
[Presentation] パーキンソン病は,膜電位を失ったミトコンドリアに対する品質管理不全病である.2009
- Author(s)
  松田憲之, 田中啓二, ら
- Organizer
  第32回日本分子生物学会大会
- Place of Presentation
  パシフイコ横浜
- Data Source
  KAKENHI-PROJECT-20770112
[Presentation] パーキンソン病は, 膜電位を失ったミトコンドリアに対する品質管理不全病である2009
- Author(s)
  松田憲之, 佐藤栄人, 柴佳保里, 尾勝圭, 税所慶子, 曽友深, 斉木臣二, 河尻澄宏, 里史明, 木村まゆみ, 小松雅明, 服部信孝, 田中啓二
- Organizer
  第32回日本分子生物学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-20770112
[Presentation] 内在性Parkinの存在様式および細胞内局在の再検討2008
- Author(s)
  税所慶子, 和栗聡, 上野隆, Klavs Hendil, 佐藤栄人, 服部信孝, 田中啓二, 松田憲之
- Organizer
  第81回日本生化学会大会(日本生化学会+日本分子生物学会, 合同大会)
- Place of Presentation
  神戸(ポートアイランド)
- Data Source
  KAKENHI-PROJECT-20770112
[Presentation] リン酸化ユビキチン：新たな「ミトコンドリア異常」伝達シグナル
- Author(s)
  松田憲之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-26650042
[Presentation] Parkin catalyzes ubiquitylation via a (ubiquitin-ester)-transfer rather than an E2-recruitment
- Author(s)
  Noriyuki Matsuda and Keiji Tanaka
- Organizer
  4th IGAKUKEN International Symposium on Cutting-edge of the Ubiquitin-Proteasome System
- Place of Presentation
  公益財団法人東京都医学総合研究所
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112522
[Presentation] Parkin catalyzes ubiquitylation via a (ubiquitin-ester)-transfer rather than an E2-recruitment
- Author(s)
  Noriyuki Matsuda and Keiji Tanaka
- Organizer
  4th IGAKUKEN International Symposium on Cutting-edge of the Ubiquitin-Proteasome System
- Place of Presentation
  公益財団法人東京都医学総合研究所
- Invited
- Data Source
  KAKENHI-PUBLICLY-24111557
[Presentation] PINK1 によってリン酸化されたユビキチンは Parkin を活性化する
- Author(s)
  小谷野史香、松田憲之
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26650042
[Presentation] リン酸化ユビキチン：新たな「ミトコンドリア異常」伝達シグナル
- Author(s)
  松田憲之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112522
[Presentation] PINK1 によってリン酸化されたユビキチンは Parkin を活性化する
- Author(s)
  小谷野史香、松田憲之
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25112522
[Presentation] Parkin catalyzes ubiquitylation via a (ubiquitin-ester)-transfer rather than an E2-recruitment
- Author(s)
  Noriyuki Matsuda and Keiji Tanaka
- Organizer
  4th IGAKUKEN International Symposium on Cutting-edge of the Ubiquitin-Proteasome System
- Place of Presentation
  公益財団法人東京都医学総合研究所
- Invited
- Data Source
  KAKENHI-PROJECT-23687018
[Presentation] リン酸化ユビキチン：新たな「ミトコンドリア異常」伝達シグナル
- Author(s)
  松田憲之
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PUBLICLY-26111729
[Presentation] PINK1 によってリン酸化されたユビキチンは Parkin を活性化する
- Author(s)
  小谷野史香、松田憲之
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-26111729

1. SAIKI Shinji (00339996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. HATTORI Nobutaka (80218510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. SATO Shigeto (00445537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. HATANO Taku (60338390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. EGUCHI Hiroto (20380868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IMOTO Masaya (60213253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANIDA Isei (30296868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KOMATSU Masaaki (90356254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. TANAKA Keiji (10108871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. AMO Taku (40453922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KOSAKO Hidetaka (10291171)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. NAKAYA Michio (80464387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ISHIZAKI Toshimasa (70293876)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Kanki Tomotake (50398088)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 佐藤美由紀 (70321768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. IMAI Kenichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 出水庸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 檜作洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 佐々木妙子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 山野晃史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 岡敏彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 武田弘資

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. 小谷野史香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 田村康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 尾勝圭

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
26. 伊藤隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 谷村進

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 両角佑一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

matsuda noriyuki 松田 憲之

MATSUDA Noriyuki 松田 憲之

Research Projects

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Co-Researchers

Molecular mechanism and physiological role of mitophagy

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Detoxification of aldehyde-conjugation as a new mechanism for preventing onset of Parkinson's diseasePrincipal Investigator

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翻訳後修飾因子の翻訳後修飾：リン酸化ユビキチンの細胞内機能の解析Principal Investigator

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PINK1の作動機構解明からミトコンドリアホメオスタシスと神経変性の核心に迫るPrincipal Investigator

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In vitro reconstitution of Parkin-mediated mitochondria quality controlPrincipal Investigator

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Identification and functional analysis of substrates of disease-associated protein kinases using multiple phosphoproteomic technologies

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ユビキチン連結酵素PARKINを活性化するメカニズムPrincipal Investigator

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パーキンソン病発症を予防するミトコンドリアストレス応答機構の解析Principal Investigator

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Collapse of mitochondrial quality control mediated by PINK1 and Parkin causes Parkinson diseasePrincipal Investigator

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Effects of mitophagy on cell death in Parkinson's disease model cells

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Ubiquitylation involved in Parkinson disease and membrane repairPrincipal Investigator

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[Journal Article] MARC-3, a membrane-associated ubiquitin ligase, is required for fast polyspermy block in Caenorhabditis elegans2024

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[Journal Article] Optineurin provides a mitophagy contact site for TBK1 activation2024

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matsuda noriyuki 松田憲之

MATSUDA Noriyuki 松田憲之