Hatano Naoya 波多野直哉

… Alternative Names

HATANO Naoya 波多野直哉

波多野直哉ハタノナオヤ

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Researcher Number	10332280
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2020: 神戸大学, 医学研究科, 医学研究員 2018 – 2020: 岡山大学, ヘルスシステム統合科学研究科, 特任講師 2016: 神戸大学, 医学研究科, 特命助教 2016: 神戸大学, 大学院医学(系)研究科, 特命助教 2014 – 2015: 神戸大学, 医学(系)研究科(研究院), 助教 … More 2013: 神戸大学, 医学(系)研究科(研究院), 特命助教 2012: 神戸大学, 医学(系)研究科(研究院), グローバルCOE研究員 2011: 神戸大学, 医学(系)研究科(研究院), グローバルＣＯＥ研究員 2011: 神戸大学, 医学(系)研究科, 研究員 2008: 神戸大学, 医学研究所, グロバールCOE研究員 2007: Kagawa University, 希少糖研究センター, 客員准教授 2005 – 2006: Kagawa Univ., Rare Suger Res.Center, Associate Prof., 希少糖研究センター, 客員助教授 2004: 香川大学, 医学部, 助手 2002: 香川医科大学, 医学部, 助手 2001: 理化学研究所, 翻訳後修飾による動的調節機構研究チーム, 連携研究員 Less
Review Section/Research Field	Principal Investigator Applied genomics / Basic Section 08030:Family and consumer sciences, and culture and living-related / Tumor diagnostics / Tumor diagnosis / Urology Except Principal Investigator Functional biochemistry / Basic Section 42040:Laboratory animal science-related / 細胞死(アポトーシス)
Keywords	Principal Investigator プロテオーム / がん / 癌 / 動物種鑑別 / 皮革 / ペプチド / 質量分析 / メタボローム / バイオマーカー / プロテオミクス / メタボロミクス / 希少糖 / 腎癌 … More Except Principal Investigator … More CaMKK / シグナル伝達 / 細胞内カルシウム / Numbl / Numb / CaM-KI / CaM-KK / カルモデュリン / CaM-キナーゼカスケード / 膵島障害 / オミクス / 病態発症機構 / 遺伝素因 / 疾患モデル / 糖尿病 / CaMK Cascade / 特異性 / CaMキナーゼI V / AMPキナーゼ / リン酸化反応 / Signal Transduction / Protein Kinase / CaMK cascade / STO-609 / AMPK / Protein phosphorylation / Signal transduction / Intracellular calcium / CaM-kinase cascade / タンパク質リン酸化 / membrane / GPR30 / Estrogen / リガンド探索 / プロテオーム / がん / アポトーシス / 心臓 / オーファン受容体 / Wolframin症候群 / MS / LC-MS / WFS1 / 海馬 / 樹状突起 / カルシウム情報伝達 / シナプス / Calmodulin / LC-MS/MS / 自己リン酸化 / 変異体 / ATPアナログ / Syndapin I / タンパク質リン酸化反 / LC-MS/ MS / GST / 機能プロテオミクス / PRG-1 / Wolframin / CaM-KIV / タンパク質リン酸化反応 / SAD-キナーゼ / CaMKKCaM-KIV / リン酸化 / シナプス可塑性 / 小脳 / IRBIT / IP3レセプター Less

Development of a simple animal species identification method for leather products by a mass spectrometerPrincipal Investigator
- Principal Investigator
  
  Hatano Naoya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Okayama University
Elucidation of genetic factors and mechanisms involved in the development and progression of type 2 diabetes using a novel rat model of the disease
- Principal Investigator
  
  YOKOI Norihide
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Kyoto University
  Kobe University
Development of an early diagnostic system for metastasis using the mass spectrometerPrincipal Investigator
- Principal Investigator
  
  Hatano Naoya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kobe University
Phosphorylation-dependent regulatory mechanism of calmoudlin-kinase cascade
- Principal Investigator
  
  Tokumitsu Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Okayama University
Development of an early diagnostic system of human pancreatic cancer using metabolite profilingPrincipal Investigator
- Principal Investigator
  
  HATANO Naoya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Kobe University
Comprehensive identification and signal transduction analysis of calmodulin-targets by functional proteomics
- Principal Investigator
  
  TOKUMITSU Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kagawa University
Identification and characterization of a novel target for CaM-kinase cascade
- Principal Investigator
  
  TOKUMITSU Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kagawa University
Possible function of IP3 receptor as a non-channel molecule
- Principal Investigator
  
  MIZUTANI Akihiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  The Institute of Physical and Chemical Research
  The University of Tokyo
プロテオミクスを用いたD-アロースによる癌細胞増殖抑制機構の解明Principal Investigator
- Principal Investigator
  
  波多野直哉
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied genomics
- Research Institution
  Kagawa University
Analysis of calmodulin-kinase cascade by using functional proteomics.
- Principal Investigator
  
  TOKUMITSU Hiroshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kagawa University
染色体欠失情報とプロテオーム解析を用いた癌抑制遺伝子の網羅的探索Principal Investigator
- Principal Investigator
  
  波多野直哉
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied genomics
- Research Institution
  Kagawa University
Screening of a ligand for hypoxia-induced receptor by negative selection method
- Principal Investigator
  
  MIZUKAMI Yoichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  細胞死(アポトーシス)
- Research Institution
  Yamaguchi University
プロテオーム解析を用いた日本人腎癌患者の腫瘍発生機構の解明Principal Investigator
- Principal Investigator
  
  波多野直哉
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  香川医科大学
   The Institute of Physical and Chemical Research

[Journal Article] Regulation of the tubulin polymerization-promoting protein by Ca2+/S100 proteins2021
- Author(s)
  Doi Seita、Fujioka Naoki、Ohtsuka Satomi、Kondo Rina、Yamamoto Maho、Denda Miwako、Magari Masaki、Kanayama Naoki、Hatano Naoya、Morishita Ryo、Hasegawa Takafumi、Tokumitsu Hiroshi
- Journal Title
  
  Cell Calcium
  
  Volume: 96 Pages: 102404-102404
- DOI
  10.1016/j.ceca.2021.102404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05231, KAKENHI-PROJECT-18K02255, KAKENHI-PROJECT-20K07896
[Journal Article] Identification and Biochemical Characterization of High Mobility Group Protein 20A as a Novel Ca2+/S100A6 Target2021
- Author(s)
  Yamamoto Maho、Kondo Rina、Hozumi Haruka、Doi Seita、Denda Miwako、Magari Masaki、Kanayama Naoki、Hatano Naoya、Morishita Ryo、Tokumitsu Hiroshi
- Journal Title
  
  Biomolecules
  
  Volume: 11 Issue: 4 Pages: 510-510
- DOI
  10.3390/biom11040510
- NAID
  120007037385
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05231, KAKENHI-PROJECT-18K02255
[Journal Article] Both IRBIT and long-IRBIT bind to and coordinately regulate Cl -/HCO 3- exchanger AE2 activity through modulating the lysosomal degradation of AE22021
- Author(s)
  Itoh, R. Hatano, N. Murakami, M. Mitsumori, K. Kawasaki, S. Wakagi, T. Kanzaki, Y. Kojima, H. Kawaai, K. Mikoshiba, K. Hamada, K. Mizutani, A.
- Journal Title
  
  Sci Rep .
  
  Volume: 16 Issue: 1 Pages: 5990-5990
- DOI
  10.1038/s41598-021-85499-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11776, KAKENHI-PROJECT-19K12807, KAKENHI-PROJECT-20K06864, KAKENHI-PROJECT-18K02255, KAKENHI-PROJECT-21K15234
[Journal Article] Occupational respiratory allergy to lettuce in lettuce farmers2020
- Author(s)
  Sekiya Reina、Nagano Tatsuya、Moriyama Tatsuya、Kishi Toshiyuki、Shinke Haruko、Yano Erika、Hatano Naoya、Katsurada Masahiro、Umezawa Kanoko、Katsurada Naoko、Hori Suya、Hazeki Nobuko、Fukunaga Atsushi、Yamamoto Masatsugu、Kamiryo Hiroshi、Shinohara Masakazu、Kobayashi Kazuyuki、Kotani Yoshikazu、Nishimura Yoshihiro
- Journal Title
  
  Clinical & Experimental Allergy
  
  Volume: 50 Issue: 8 Pages: 932-941
- DOI
  10.1111/cea.13682
- NAID
  120006877484
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08651, KAKENHI-PROJECT-19K05919, KAKENHI-PROJECT-18K02255
[Journal Article] Development and Characterization of Novel Molecular Probes for Ca2+/Calmodulin-Dependent Protein Kinase Kinase, Derived from STO-609.2020
- Author(s)
  Ohtsuka S, Ozeki Y, Fujiwara M, Miyagawa T, Kanayama N, Magari M, Hatano N, Suizu F, Ishikawa T, and Tokumitsu H.
- Journal Title
  
  Biochemistry
  
  Volume: 59(17) Issue: 17 Pages: 1701-1710
- DOI
  10.1021/acs.biochem.0c00149
- NAID
  120007027579
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03447, KAKENHI-PROJECT-18K02255, KAKENHI-PROJECT-18K06113
[Journal Article] Phosphorylation and dephosphorylation of Ca2+/calmodulin-dependent protein kinase kinase β at Thr144 in HeLa cells2020
- Author(s)
  Takabatake Shota、Fukumoto Yusei、Ohtsuka Satomi、Kanayama Naoki、Magari Masaki、Sakagami Hiroyuki、Hatano Naoya、Tokumitsu Hiroshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 525 Issue: 1 Pages: 251-257
- DOI
  10.1016/j.bbrc.2020.02.056
- NAID
  120006961125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K02255, KAKENHI-PROJECT-18K06113
[Journal Article] Identification of specific protein amino acid substitutions of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli ST131: a proteomics approach using mass spectrometry2019
- Author(s)
  Nakamura Akihiro、Komatsu Masaru、Ohno Yuki、Noguchi Nobuyoshi、Kondo Akira、Hatano Naoya
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 8555-8555
- DOI
  10.1038/s41598-019-45051-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K02255
[Journal Article] Glucose-regulated protein 78 (GRP78) binds directly to PIP3 phosphatase SKIP and determines its localization.2016
- Author(s)
  Ijuin T, Hatano N, Takenawa T.
- Journal Title
  
  Genes to Cells
  
  Volume: 21(5) Issue: 5 Pages: 457-465
- DOI
  10.1111/gtc.12353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430143
[Journal Article] Identification of putative biomarkers for prediabetes by metabolome analysis of rat models of type 2 diabetes2015
- Author(s)
  Yokoi N, Beppu M, Yoshida E, Hoshikawa R, Hidaka S, Matsubara T, Shinohara M, Irino Y, Hatano N, Seino S
- Journal Title
  
  Metabolomics
  
  Volume: 印刷中 Issue: 5 Pages: 1277-1286
- DOI
  10.1007/s11306-015-0784-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24500491, KAKENHI-PROJECT-26430143
[Journal Article] Regulation of insulin signaling in skeletal muscle by PIP3 phosphatase, SKIP, and endoplasmic reticulum molecular chaperone glucose-regulated protein 78.2015
- Author(s)
  Ijuin T, Hatano N, Hosooka T, Takenawa T.
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1853(12) Issue: 12 Pages: 3192-3201
- DOI
  10.1016/j.bbamcr.2015.09.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430143, KAKENHI-PROJECT-23227005, KAKENHI-PROJECT-25460365
[Journal Article] Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion2014
- Author(s)
  Gheni G, Ogura M, Iwasaki M, Yokoi N, Minami K, Nakayama Y, Harada K, Hastoy B, Wu X, Takahashi H, Kimura K, Matsubara T, Hoshikawa R, Hatano N, Sugawara K, Shibasaki T, Inagaki N, Bamba T, Mizoguchi A, Fukusaki E, Rorsman P, Seino S
- Journal Title
  
  Cell Rep
  
  Volume: 9 Issue: 2 Pages: 661-673
- DOI
  10.1016/j.celrep.2014.09.030
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24229007, KAKENHI-PROJECT-24500491, KAKENHI-PROJECT-24590320, KAKENHI-PROJECT-24591330, KAKENHI-PROJECT-25293210, KAKENHI-PROJECT-25461351, KAKENHI-PROJECT-25640022, KAKENHI-PROJECT-25860749, KAKENHI-PROJECT-26430143
[Journal Article] Identification of amphiphysin 1 as an endogenous substrate for CDKL5, a protein kinase associated with X-linked neurodevelopmental disorder.2013
- Author(s)
  Sekiguchi M, Katayama S, Hatano N, Shigeri Y, Sueyoshi N, Kameshita I.
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 535(2) Issue: 2 Pages: 257-267
- DOI
  10.1016/j.abb.2013.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501296, KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-25850244
[Journal Article] Serum metabolomics as a novel diagnostic approach for gastrointestinal cancer2012
- Author(s)
  Atsuki Ikeda
- Journal Title
  
  Biomedical chromatography
  
  Volume: (印刷中)(掲載確定) Issue: 5 Pages: 548-558
- DOI
  10.1002/bmc.1671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790645, KAKENHI-PROJECT-23501296, KAKENHI-PROJECT-23686120
[Journal Article] PKL01, an Ndr kinase homologue in plant, shows tyrosine kinase activity2012
- Author(s)
  Katayama S, Sugiyama Y, Hatano N, Terachi T, Sueyoshi N, Kameshita I
- Journal Title
  
  J. Biochem
  
  Volume: 152(4) Issue: 4 Pages: 347-353
- DOI
  10.1093/jb/mvs075
- NAID
  10031166148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501296
[Journal Article] Nitric oxide prevents phosphorylation of neuronal nitric oxide synthase at serine 1412 by inhibiting the Akt/PKB and CaM-K II signaling pathways.2012
- Author(s)
  Song T, Hatano N, Sugimoto K, Horii M, Yamaguchi F, Tokuda M, Miyamoto Y, Kambe T, Watanabe Y.
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 30(1) Pages: 15-20
- DOI
  10.3892/ijmm.2012.971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501296, KAKENHI-PROJECT-24590183
[Journal Article] Diagnosis of gastroenterological diseases by metabolome analysis using gas chromatography-mass spectrometry2012
- Author(s)
  Yoshida M, Hatano N, Nishiumi S, Irino Y, Izumi Y, Takenawa T, Azuma T
- Journal Title
  
  J. Gastroenterol
  
  Volume: 47(1) Issue: 1 Pages: 9-20
- DOI
  10.1007/s00535-011-0493-8
- NAID
  10030295488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501296, KAKENHI-PROJECT-24700455, KAKENHI-PROJECT-24701005
[Journal Article] Tumor suppressor cell adhesion molecule 1 (CADM1) is cleaved by a disintegrin and metalloprotease 10 (ADAM10) and subsequently cleaved by γ-secretase complex2012
- Author(s)
  長柄雄介
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 417 Issue: 1 Pages: 462-467
- DOI
  10.1016/j.bbrc.2011.11.140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J10138, KAKENHI-PROJECT-22300336, KAKENHI-PROJECT-22590653, KAKENHI-PUBLICLY-23115705, KAKENHI-PROJECT-23501296, KAKENHI-PROJECT-23700439
[Journal Article] Generation of Autonomous Activity of Ca^<2+>/ Calmodulin-Dependent Protein Kinase Kinaseβby Autophosphorylation2011
- Author(s)
  Tokumitsu H, Hatano N, Fujimoto T, Yurimoto S, and Kobayashi R
- Journal Title
  
  Biochemistry
  
  Volume: 50 Pages: 8193-8201
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Identification of a novel CaMKK substrate2011
- Author(s)
  Tomohito Fujimoto, et al
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 410 Issue: 1 Pages: 45-51
- DOI
  10.1016/j.bbrc.2011.05.102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J08571, KAKENHI-PROJECT-21570143, KAKENHI-PROJECT-23501296
[Journal Article] Generation of Autonomous Activity of Ca^<2+>/Calmodulin-Dependent Protein Kinase Kinase β by Autophosphorylation2011
- Author(s)
  Tokumitsu H, et al
- Journal Title
  
  Biochemistry
  
  Volume: 50 Issue: 38 Pages: 8193-8201
- DOI
  10.1021/bi201005g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570143, KAKENHI-PROJECT-23501296
[Journal Article] Serum fatty acid profiling of colorectal cancer by gas chromatography/mass spectrometry2011
- Author(s)
  Kondo Y, Nishiumi S, Shinohara M, Hatano N, Ikeda A, Yoshie T, Kobayashi T, Shiomi Y, Iruno Y, Takenawa T, Azuma T, Yoshida M
- Journal Title
  
  Biomark. Med
  
  Volume: 5(4) Issue: 4 Pages: 451-460
- DOI
  10.2217/bmm.11.41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501296
[Journal Article] GC/MS-based profiling of amino acids and TCA cycle-related molecules in ulcerative colitis2011
- Author(s)
  Ooi M, Nishiumi S, Yoshie T, Shiomi Y, Kohashi M, Fukunaga K, Nakamura S, Matsumoto T, Hatano N, Shinohara M, Irino Y, Takenawa T, Azuma T, Yohida M
- Journal Title
  
  Inflamm. Res
  
  Volume: 60(9) Issue: 9 Pages: 831-840
- DOI
  10.1007/s00011-011-0340-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501296
[Journal Article] Identification of a novel CaMKK substrate2011
- Author(s)
  Fujimoto T, Hatano N, Nozaki N, Yurimoto S, Kobayashi R, and Tokumitsu H
- Journal Title
  
  Biochem. Biophys. Res. Comm
  
  Volume: 410 Pages: 45-51
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Inactivation of Ca^<2+>/ calmodulin-dependent protein kinase I by S-glutathionylation of the active-site cysteine residue2010
- Author(s)
  Kambe T, Song T, Takata T, Hatano N, Miyamoto Y, Nozaki N, Naito Y, Tokumitsu H, and Watanabe Y
- Journal Title
  
  FEBS Lett
  
  Volume: 584 Pages: 2478-2484
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Identification and characterization of wolframin, the product of the wolfram syndrome gene(WFS1), as a novel calmodulin-binding protein2009
- Author(s)
  Yurimoto S, Hatano N, Tsuchiya M, Kato K, Fujimoto T, Masaki T, Kobayashi R, and Tokumitsu H
- Journal Title
  
  Biochemistry
  
  Volume: 48 Pages: 3946-3955
- Data Source
  KAKENHI-PROJECT-21570143
[Journal Article] Activation of SAD Kinase by Ca2+/Calmodulin-dependent Protein Kinase Kinase2008
- Author(s)
  Fujimoto T, Yurimoto S, Hatano N, Nozaki N, Sueyoshi N, Kameshita I, Mizutani A, Mikoshiba K, Kobayashi R, and Tokumitsu H
- Journal Title
  
  Biochemistry 47(13)
  
  Pages: 4151-4159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570134
[Journal Article] Phosphorylation of Numb regulates its interaction with the clathrin-associated adaptor AP-2.2006
- Author(s)
  H.Tokumitsu, N.Hatano, S.Yokokura, Y.Sueyoshi, N.Nozaki, R.Kobayashi
- Journal Title
  
  FEBS Letters 580(24)
  
  Pages: 5797-5801
- NAID
  120007015428
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570115
[Journal Article] Phosphorylation of Numb family proteins. Possible involvement of Ca2+/calmodulin-dependent protein kinases.2005
- Author(s)
  Tokumitsu H, Hatano N, Inuzuka H, Sueyoshi Y, Yokokura S, Ichimura T, Nozaki N, Kobayashi R.
- Journal Title
  
  J.Biol.Chem. 380(42)
  
  Pages: 35108-35118
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16601002
[Journal Article] Phosphorylation of Numb family proteins. : Possible involvement of Ca^<2+>/calmodulin-dependent protein kinases.2005
- Author(s)
  H.Tokumitsu, N.Hatano, H.Inuzuka, Y.Sueyoshi, S.Yokokura, T.Ichimura, N.Nozaki, R.Kobayashi
- Journal Title
  
  Journal of Biological Chemistry 280(42)
  
  Pages: 35108-35118
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570115
[Journal Article] Mechanism of the generation of autonomous activity of Ca2+/calmodulin-dependent protein kinase IV2004
- Author(s)
  Tokumitsu H, Hatano N, Inuzuka H, Yokokura S, Nozaki N, Kobayashi R.
- Journal Title
  
  J.Biol.Chem. 279(39)
  
  Pages: 40296-40302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16601002
[Journal Article] Calcium/calmodulin-dependent protein kinase I inhibits neuronal nitric-oxide synthase activity through serine 741 phosphorylation.2004
- Author(s)
  Song T, Hatano N, Horii M, Tokumitsu H, Yamaguchi F, Tokuda M, Watanabe Y.
- Journal Title
  
  FEBS Lett. 570(1-3)
  
  Pages: 133-137
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16601002
[Journal Article] Regulatory mechanism of Dictyostelium myosin light chain kinase A.2004
- Author(s)
  Tokumitsu H, Hatano N, Inuzuka H, Ishikawa Y, Uyeda TQ, Smith JL, Kobayashi R.
- Journal Title
  
  J.Biol.Chem. 279(1)
  
  Pages: 42-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16601002
[Presentation] 肥満糖尿病モデルZFDMラットの膵島におけるタンパク質糖鎖修飾の病態生理学的意義2018
- Author(s)
  横井伯英、速水智英、波多野直哉、日高志保美、川畑綾子、星野貴一、星野雅行、清野　進
- Organizer
  第65回日本実験動物会総会
- Data Source
  KAKENHI-PROJECT-18H02364
[Presentation] Metabolome and proteome analysis of cancer2013
- Author(s)
  波多野直哉
- Organizer
  SYMPOSIUM : A career in calcium signaling
- Place of Presentation
  高松・香川大学医学部
- Year and Date
  2013-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-23501296
[Presentation] 乳がん細胞でのPI3K インヒビターによる代謝変化2013
- Author(s)
  波多野直哉、入野康宏、竹縄忠臣
- Organizer
  第86回日本生化学大会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-23501296
[Presentation] The establishment of metabolic proteome analysis by stable isotope2012
- Author(s)
  波多野直哉、入野康宏、竹縄忠臣
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡・マリンメッセ福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-23501296
[Presentation] Characterization of breast cancer cells with metabolic profiling2012
- Author(s)
  入野康宏、平田悠、竹内由紀子、波多野直哉、竹縄忠臣
- Organizer
  85回日本生化学大会
- Place of Presentation
  福岡・マリンメッセ福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23501296
[Presentation] Identification of a novel target for Ca^<2+>/ CaM-dependent protein kinase kinase by using an ATP analogue2011
- Author(s)
  藤本智仁, 波多野直哉, 野崎直仁, 横倉(揺本)沙紀, 小林良二, 徳光浩
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21570143
[Presentation] Regulatory Mechanism of CaMKK by Autophosphorylation2011
- Author(s)
  徳光浩、横倉(揺本)沙紀、波多野直哉、藤本智仁、小林良二
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21570143
[Presentation] PRG-1(plasticity related gene 1), a novel neuronal calmodulin-binding protein2010
- Author(s)
  徳光浩、波多野直哉、土屋光正、横倉(揺本)沙紀、藤本智仁、小原直樹、小林良二、阪上洋行
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会,合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21570143
[Presentation] 乳がん細胞でのPI3Kインヒビターによる代謝変化
- Author(s)
  波多野直哉、入野康宏、竹縄忠臣
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23501296
[Presentation] The establishment of metabolic proteome analysis by stable isotope
- Author(s)
  Naoya Hatano, Yasuhiro Irino, Tadaomi Takenawa
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23501296
[Presentation] Characterization of breast cancer cells with metabolic profiling
- Author(s)
  入野康宏、平田悠、竹内由紀子、波多野直哉、竹縄忠臣
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23501296
[Presentation] Metabolome and Proteome Analysis of Cancer
- Author(s)
  Naoya Hatano
- Organizer
  SYMPOSIUM: A career in calcium signaling
- Place of Presentation
  高松・香川大学医学部
- Invited
- Data Source
  KAKENHI-PROJECT-23501296

1. TOKUMITSU Hiroshi (20237077)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
2. KOBAYASHI Ryoji (00020917)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. MIZUTANI Akihiro (30242861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MIZUKAMI Yoichi (80274158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. AKI Toshihiko (60304474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. YOKOI Norihide (70311610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 曲正樹 (50359882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 谷口幸雄 (10252496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 須山幹太 (70452365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUKUNAGA Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. SUIZU Futoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 清野進

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 金山直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 濱田浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 長柄雄介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 柴崎忠雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 南幸太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hatano Naoya 波多野 直哉

HATANO Naoya 波多野 直哉

波多野 直哉 ハタノ ナオヤ

Research Projects

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Co-Researchers

Development of a simple animal species identification method for leather products by a mass spectrometerPrincipal Investigator

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Elucidation of genetic factors and mechanisms involved in the development and progression of type 2 diabetes using a novel rat model of the disease

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Development of an early diagnostic system for metastasis using the mass spectrometerPrincipal Investigator

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Phosphorylation-dependent regulatory mechanism of calmoudlin-kinase cascade

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Development of an early diagnostic system of human pancreatic cancer using metabolite profilingPrincipal Investigator

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Comprehensive identification and signal transduction analysis of calmodulin-targets by functional proteomics

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Identification and characterization of a novel target for CaM-kinase cascade

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Possible function of IP3 receptor as a non-channel molecule

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プロテオミクスを用いたD-アロースによる癌細胞増殖抑制機構の解明Principal Investigator

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Analysis of calmodulin-kinase cascade by using functional proteomics.

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染色体欠失情報とプロテオーム解析を用いた癌抑制遺伝子の網羅的探索Principal Investigator

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Screening of a ligand for hypoxia-induced receptor by negative selection method

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プロテオーム解析を用いた日本人腎癌患者の腫瘍発生機構の解明Principal Investigator

Principal Investigator

Hatano Naoya 波多野直哉

HATANO Naoya 波多野直哉

波多野直哉ハタノナオヤ