• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Miyamoto Yoichi  宮本 洋一

… Alternative Names

MIYAMOTO Yoichi  宮本 洋一

宮本 洋一  ミヤモト ヨウイチ

Less
Researcher Number 10379084
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-4016-1119
Affiliation (Current) 2025: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 創薬デザイン研究センター, 主任研究員
Affiliation (based on the past Project Information) *help 2023 – 2024: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 創薬デザイン研究センター, 主任研究員
2022: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 創薬デザイン研究センター, サブプロジェクトリーダー
2020 – 2021: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 細胞核輸送ダイナミクスプロジェクト, サブプロジェクトリーダー
2018: 国立研究開発法人医薬基盤・健康・栄養研究所, 細胞核輸送ダイナミクスプロジェクト, サブプロジェクトリーダー
2015 – 2017: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 細胞核輸送ダイナミクスプロジェクト, サブプロジェクトリーダー … More
2014: 独立行政法人医薬基盤研究所, 創薬基盤研究部, 研究員
2006: 阪大, 助手
2005: 大阪大学, 生命機能研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Cell biology / Basic Section 44010:Cell biology-related / Medium-sized Section 48:Biomedical structure and function and related fields / Basic Section 42030:Animal life science-related / Biological Sciences
Except Principal Investigator
Basic Section 49060:Virology-related / Cell biology
Keywords
Principal Investigator
核輸送 / クロマチン / インポーティン / Importin / 精子細胞形成 / 遺伝子発現制御 / Importin alpha / 細胞核 / 染色体不安定化 / 微小核 … More / 核-細胞質間物質輸送 / 不妊症 / 配偶子形成 / 卵 / 女性不妊症 / 雄性不妊 / KPNA4 / 精子形成 / ノックアウトマウス / 雄性不妊症 / 細胞亜型 / 乳がん / Importin-α / NLS / 核局在化シグナル / 転写調節 / がん / 核移行シグナル / 核-細胞質間輸送 / Importin α / ストレス応答 / ヌクレオポリン / 核膜孔複合体 / 核タンパク質輸送 … More
Except Principal Investigator
細胞核 / ウイルス学 / 代謝フラックス / エネルギー代謝 / 細胞死 / 蛋白質翻訳 / 翻訳 / フラビウイルス / 解糖系 / ワクチン / ATP / デングウイルス / 日本脳炎ウイルス / 老化 / 癌 / 細胞・組織 / ノックアウトマウス / がん細胞 / importin / 核輸送 Less
  • Research Projects

    (9 results)
  • Research Products

    (68 results)
  • Co-Researchers

    (19 People)
  •  微小核の本態解明を目指したImportin-α1の新機能探索Principal Investigator

    • Principal Investigator
      宮本 洋一
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Exploring a novel function of nuclear transport molecules in male and female gametogenesis and elucidation of the infertility mechanismPrincipal Investigator

    • Principal Investigator
      宮本 洋一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Elucidation of the pathogenic mechanism of structural abnormality of sperm caused by Importin-alpha4 deficiency and serach for a new mechanism of sperm morphogenesisPrincipal Investigator

    • Principal Investigator
      MIYAMOTO Yoichi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42030:Animal life science-related
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Elucidation of protein translation shutoff by mosquito-borne flavivirus

    • Principal Investigator
      TORU OKAMOTO
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Juntendo University
      Osaka University
  •  The roles of importin-alpha subfamilies in mammals

    • Principal Investigator
      Yoneda Yoshihiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Elucidation of gene expression regulation mechanism in cancer cells focusing on multifunctionality of Importin-alphaPrincipal Investigator

    • Principal Investigator
      MIYAMOTO Yoichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Importinαの新規分子認識機構の解明Principal Investigator

    • Principal Investigator
      宮本 洋一
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Cell biology
    • Research Institution
      独立行政法人医薬基盤研究所
  •  細胞環境の変化に応答した核膜孔複合体構成分子の動態に関する研究Principal Investigator

    • Principal Investigator
      宮本 洋一
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Importinαの核内における新たな機能の探索と細胞核ストレス応答Principal Investigator

    • Principal Investigator
      宮本 洋一
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cell biology
    • Research Institution
      Osaka University

All 2024 2023 2022 2021 2020 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book Patent

  • [Book] タンパク質・RNAの核―細胞質間輸送、阻害剤・活性化剤ハンドブック2018

    • Author(s)
      宮本洋一、岡正啓、米田悦啓
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16H04789
  • [Book] Nuclear Architecture and Dynamics2018

    • Author(s)
      Miyamoto Y, Yoneda Y, Oka M.
    • Total Pages
      618
    • Publisher
      Academic press
    • Data Source
      KAKENHI-PROJECT-16H04789
  • [Book] 核-細胞質間蛋白質輸送と創薬研究, 医学の歩み2018

    • Author(s)
      宮本洋一,米田悦啓
    • Total Pages
      280
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-16H04789
  • [Book] Nuclear Architecture and Dynamics2017

    • Author(s)
      Miyamoto Y., Yoneda Y., Oka M.
    • Total Pages
      569
    • Publisher
      Academic press
    • ISBN
      9780128034804
    • Data Source
      KAKENHI-PROJECT-15K07068
  • [Journal Article] A Kpna1-deficient psychotropic drug-induced schizophrenia model mouse for studying gene?environment interactions2024

    • Author(s)
      Nomiya Hirotaka、Sakurai Koki、Miyamoto Yoichi、Oka Masahiro、Yoneda Yoshihiro、Hikida Takatoshi、Yamada Masami
    • Journal Title

      Scientific Reports

      Volume: 14 Issue: 1 Pages: 3376-3376

    • DOI

      10.1038/s41598-024-53237-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KK0111, KAKENHI-PROJECT-23K24205, KAKENHI-PROJECT-23K27373
  • [Journal Article] Karyopherin α deficiency contributes to human preimplantation embryo arrest2023

    • Author(s)
      Wang Wenjing、Miyamoto Yoichi、Chen B.、Shi J.、Diao F.、Zheng W.、Li Q.、Yu L.、Li L.、Xu Y.、Wu L.、Mao X.、Fu J.、Li B.、Yan Z.、Shi R.、Xue X.、Mu J.、Zhang Z.、Wu T.、Zhao L.、Wang W.、Zhou Z.、Dong J.、Li Q.、Jin L.、He L.、Sun X.、Lin G.、Kuang Y.、Wang L.、Sang Q.
    • Journal Title

      Journal of Clinical Investigation

      Volume: 133 Issue: 2

    • DOI

      10.1172/jci159951

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KK0111, KAKENHI-PROJECT-20K06455
  • [Journal Article] Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure2023

    • Author(s)
      Oka Masahiro、Otani Mayumi、Miyamoto Yoichi、Oshima Rieko、Adachi Jun、Tomonaga Takeshi、Asally Munehiro、Nagaoka Yuya、Tanaka Kaori、Toyoda Atsushi、Ichikawa Kazuki、Morishita Shinichi、Isono Kyoichi、Koseki Haruhiko、Nakato Ryuichiro、Ohkawa Yasuyuki、Yoneda Yoshihiro
    • Journal Title

      Cell Reports

      Volume: 42 Issue: 8 Pages: 112884-112884

    • DOI

      10.1016/j.celrep.2023.112884

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KK0111, KAKENHI-PROJECT-22K19275, KAKENHI-PLANNED-19H05745, KAKENHI-PUBLICLY-22H04676, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23H00372, KAKENHI-PROJECT-23K27373
  • [Journal Article] Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex2023

    • Author(s)
      Katahira Jun、Ohmae Tatsuya、Yasugi Mayo、Sasaki Ryosuke、Itoh Yumi、Kohda Tomoko、Hieda Miki、Yokota Hirai Masami、Okamoto Toru、Miyamoto Yoichi
    • Journal Title

      Nucleic Acids Research

      Volume: 51 Issue: 14 Pages: 7602-7618

    • DOI

      10.1093/nar/gkad483

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KK0111, KAKENHI-PROJECT-22K06227
  • [Journal Article] ACAGT‐007a, an anti‐cancer compound that modulates ERK MAPK signaling, induces nuclear enrichment of phosphorylated ERK in T3M4 pancreatic cancer cells2023

    • Author(s)
      Khandakar Golam Iftakhar、Miyamoto Yoichi、Satoh Ryosuke、Kishimoto Kenta、Xie Mingzuo、Shih Mengyu、Takasaki Teruaki、Tanabe Genzoh、Oka Masahiro、Sugiura Reiko
    • Journal Title

      Genes to Cells

      Volume: - Issue: 6 Pages: 457-465

    • DOI

      10.1111/gtc.13026

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KK0111, KAKENHI-PROJECT-19H03376, KAKENHI-PROJECT-20H03444, KAKENHI-PROJECT-20K06455, KAKENHI-PROJECT-23K27373
  • [Journal Article] Importin α3 (KPNA3) Deficiency Augments Effortful Reward-Seeking Behavior in Mice2022

    • Author(s)
      Aomine Yoshiatsu、Sakurai Koki、Macpherson Tom、Ozawa Takaaki、Miyamoto Yoichi、Yoneda Yoshihiro、Oka Masahiro、Hikida Takatoshi
    • Journal Title

      Frontiers in Neuroscience

      Volume: 16 Pages: 1-13

    • DOI

      10.3389/fnins.2022.905991

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K18557, KAKENHI-PUBLICLY-21H05694, KAKENHI-PROJECT-20H03444, KAKENHI-PROJECT-20K06455, KAKENHI-PROJECT-21K15210, KAKENHI-PUBLICLY-21H00311, KAKENHI-PROJECT-23K22376, KAKENHI-PROJECT-23K24205
  • [Journal Article] SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication2022

    • Author(s)
      Miyamoto Yoichi、Itoh Yumi、Suzuki Tatsuya、Tanaka Tomohisa、Sakai Yusuke、Koido Masaru、Hata Chiaki、Wang Cai-Xia、Otani Mayumi、Moriishi Kohji、Tachibana Taro、Kamatani Yoichiro、Yoneda Yoshihiro、Okamoto Toru、Oka Masahiro
    • Journal Title

      Communications Biology

      Volume: 5 Issue: 1 Pages: 483-483

    • DOI

      10.1038/s42003-022-03427-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03444, KAKENHI-PROJECT-20H03495, KAKENHI-PROJECT-20K06455
  • [Journal Article] Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques2022

    • Author(s)
      Nagatake T, Kishino S, Urano E, et al.
    • Journal Title

      Mucosal Immunology

      Volume: 15 Issue: 2 Pages: 289-300

    • DOI

      10.1038/s41385-021-00477-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07617, KAKENHI-PROJECT-20K21643, KAKENHI-WRAPUP-20H05613, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H03444, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-20K06455, KAKENHI-PROJECT-20K07333, KAKENHI-PROJECT-22K15004, KAKENHI-PROJECT-21K19395, KAKENHI-PROJECT-23K20389, KAKENHI-PROJECT-21H02757
  • [Journal Article] Establishment of a stable SARS-CoV-2 replicon system for application in high-throughput screening2022

    • Author(s)
      Tanaka Tomohisa、Saito Akatsuki、Suzuki Tatsuya、Miyamoto Yoichi、Takayama Kazuo、Okamoto Toru、Moriishi Kohji
    • Journal Title

      Antiviral Research

      Volume: 199 Pages: 105268-105268

    • DOI

      10.1016/j.antiviral.2022.105268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06382, KAKENHI-PROJECT-20K06455
  • [Journal Article] Importins: Diverse roles in male fertility2022

    • Author(s)
      Nathaniel Benedict, Whiley Penny, Miyamoto Yoichi, Loveland Kate
    • Journal Title

      Seminars in Cell & Developmental Biology

      Volume: 121 Pages: 82-98

    • DOI

      10.1016/j.semcdb.2021.08.002

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06455
  • [Journal Article] Establishment of monoclonal antibodies broadly neutralize infection of hepatitis B virus.2022

    • Author(s)
      Zhang H, Itoh Y, Suzuki T, Ihara KI, Tanaka T, Haga S, Enatsu H, Yumiya M, Kimura M, Takada A, Itoh D, Shibazaki Y, Nakao S, Yoshio S, Miyakawa K, Miyamoto Y, Sasaki H, Kajita T, Sugiyama M, Mizokami M, Tachibana T, Ryo A, Moriishi K, Miyoshi E, Kanto T, Okamoto T, Matsuura Y.
    • Journal Title

      Microbiol Immunol.

      Volume: 66(4) Issue: 4 Pages: 179-192

    • DOI

      10.1111/1348-0421.12964

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03495, KAKENHI-PROJECT-23K24228
  • [Journal Article] Effects of Importin α1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice2021

    • Author(s)
      Sakurai Koki, Itou Taichi, Morita Makiko, Kasahara Emiko, Moriyama Tetsuji, Macpherson Tom, Ozawa Takaaki, Miyamoto Yoichi, Yoneda Yoshihiro, Sekiyama Atsuo, Oka Masahiro, Hikida Takatoshi
    • Journal Title

      PLOS ONE

      Volume: 16 Issue: 11 Pages: e0258364-e0258364

    • DOI

      10.1371/journal.pone.0258364

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K03385, KAKENHI-PROJECT-18H02542, KAKENHI-PUBLICLY-21H00311, KAKENHI-PUBLICLY-21H05694, KAKENHI-PROJECT-19H01769, KAKENHI-PROJECT-20H03444, KAKENHI-PROJECT-20K06455, KAKENHI-PROJECT-21K18557
  • [Journal Article] Novel anti-flavivirus drugs targeting the nucleolar distribution of core protein2020

    • Author(s)
      Tokunaga Makoto、Miyamoto Yoichi、Suzuki Tatsuya、Otani Mayumi、Inuki Shinsuke、Esaki Tsuyoshi、Nagao Chioko、Mizuguchi Kenji、Ohno Hiroaki、Yoneda Yoshihiro、Okamoto Toru、Oka Masahiro、Matsuura Yoshiharu
    • Journal Title

      Virology

      Volume: 541 Pages: 41-51

    • DOI

      10.1016/j.virol.2019.11.015

    • Peer Reviewed
    • Data Source
      KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-17H03679, KAKENHI-PROJECT-19H03479, KAKENHI-PROJECT-20K06455
  • [Journal Article] Total Synthesis of Dictyodendrins A-F by the Gold‐Catalyzed Cascade Cyclization of Conjugated Diyne with Pyrrole2020

    • Author(s)
      Matsuoka Junpei、Inuki Shinsuke、Matsuda Yuka、Miyamoto Yoichi、Otani Mayumi、Oka Masahiro、Oishi Shinya、Ohno Hiroaki
    • Journal Title

      Chemistry - A European Journal

      Volume: 26 Issue: 49 Pages: 11150-11157

    • DOI

      10.1002/chem.202001950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K06455, KAKENHI-PROJECT-17H03971
  • [Journal Article] Genetic loss of importin α4 causes abnormal sperm morphology and impacts on male fertility in mouse2020

    • Author(s)
      Miyamoto Yoichi、Sasaki Mitsuho、Miyata Haruhiko、Monobe Yoko、Nagai Masahiro、Otani Mayumi、Whiley Penny A. F.、Morohoshi Akane、Oki Shinya、Matsuda Junichiro、Akagi Ken‐ichi、Adachi Jun、Okabe Masaru、Ikawa Masahito、Yoneda Yoshihiro、Loveland Kate L.、Oka Masahiro
    • Journal Title

      The FASEB Journal

      Volume: 34 Issue: 12 Pages: 16224-16242

    • DOI

      10.1096/fj.202000768rr

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06455, KAKENHI-PROJECT-20H03444, KAKENHI-PROJECT-19H03424, KAKENHI-PROJECT-18KT0024
  • [Journal Article] Development of oligonucleotide-based antagonists of Ebola virus protein 24 inhibiting its interaction with karyopherin alpha 12018

    • Author(s)
      Tanaka Keisuke、Kasahara Yuuya、Miyamoto Yoichi、Takumi Okuda、Kasai Tatsuro、Onodera Kentaro、Kuwahara Masayasu、Oka Masahiro、Yoneda Yoshihiro、Obika Satoshi
    • Journal Title

      Organic & Biomolecular Chemistry

      Volume: 16 Issue: 24 Pages: 4456-4463

    • DOI

      10.1039/c8ob00706c

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04789, KAKENHI-PROJECT-17H03679
  • [Journal Article] Correction: Development of oligonucleotide-based antagonists of Ebola virus protein 24 inhibiting its interaction with karyopherin alpha 12018

    • Author(s)
      Tanaka Keisuke、Kasahara Yuuya、Miyamoto Yoichi、Okuda Takumi、Kasai Tatsuro、Onodera Kentaro、Kuwahara Masayasu、Oka Masahiro、Yoneda Yoshihiro、Obika Satoshi
    • Journal Title

      Organic & Biomolecular Chemistry

      Volume: 16 Issue: 40 Pages: 7530-7530

    • DOI

      10.1039/c8ob90140f

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04789, KAKENHI-PROJECT-17H03679
  • [Journal Article] Development of a pipeline for automated, high-throughput analysis of paraspeckle proteins reveals specific roles for importin α proteins.2017

    • Author(s)
      Major A.T., Miyamoto Y., Lo C., Jans D.A., Loveland K.L.
    • Journal Title

      Sci. Rep.

      Volume: 7 Issue: 1 Pages: 43323-43323

    • DOI

      10.1038/srep43323

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07068
  • [Journal Article] Data on dimer formation between importin α subtypes2016

    • Author(s)
      Miyamoto Y., Oka M.
    • Journal Title

      Data in Brief

      Volume: 7 Pages: 1248-1253

    • DOI

      10.1016/j.dib.2016.03.080

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07068, KAKENHI-PROJECT-16K14676
  • [Journal Article] Molecular Mechanism of HIV-1 Vpr for Binding to Importin-α.2016

    • Author(s)
      Miyatake H., Sanjoh A., Murakami T., Murakami H., Matsuda G., Hagiwara K., Yokoyama M., Sato H., Miyamoto Y., Dohmae N., Aida Y.
    • Journal Title

      J. Mol. Biol.

      Volume: 428 Issue: 13 Pages: 2744-2757

    • DOI

      10.1016/j.jmb.2016.05.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07068, KAKENHI-PROJECT-16K08824
  • [Journal Article] Importin α: a key molecule in nuclear transport and non-transport functions.2016

    • Author(s)
      Miyamoto Y, Yamada K, Yoneda Y.
    • Journal Title

      J Biochem

      Volume: 160 Issue: 2 Pages: 69-75

    • DOI

      10.1093/jb/mvw036

    • NAID

      40020914020

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-25116008, KAKENHI-PROJECT-16H04789, KAKENHI-PROJECT-15K07068, KAKENHI-PROJECT-16K18434
  • [Journal Article] Cell surface localization of importin α1/KPNA2 affects cancer cell proliferation by regulating FGF1 signalling2016

    • Author(s)
      Yamada K., Miyamoto Y., Tsujii A., Moriyama T., Ikuno Y., Shiromizu T., Serada S., Fujimoto M., Tomonaga T., Naka T., Yoneda Y., Oka M.
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 231410-231410

    • DOI

      10.1038/srep21410

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07068, KAKENHI-PROJECT-26870341, KAKENHI-PROJECT-26670614, KAKENHI-PROJECT-25290054, KAKENHI-PLANNED-25116008
  • [Journal Article] Retinoblastoma Binding Protein 4-Regulated Classical Nuclear Transport Is Involved in Cellular Senescence2015

    • Author(s)
      Tsujii A., Miyamoto Y., Moriyama T., Tsuchiya T., Obuse C., Mizuguchi K., Oka M., Yoneda Y.
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 290 Issue: 49 Pages: 29375-29388

    • DOI

      10.1074/jbc.m115.681908

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07068, KAKENHI-PROJECT-26650002, KAKENHI-PROJECT-26870341, KAKENHI-PROJECT-25430186, KAKENHI-PLANNED-25116004, KAKENHI-PLANNED-25116008
  • [Journal Article] Crystal structure of human importin-α1 (Rch1), revealing a potential autoinhibition mode involving homodimerization2015

    • Author(s)
      Miyatake H., Sanjoh A., Unzaic S., Matsuda G., Tatsumi Y., Miyamoto Y., Dohmae N. and Aida Y.
    • Journal Title

      PLoS One

      Volume: 10(2) Issue: 2 Pages: 1-14

    • DOI

      10.1371/journal.pone.0115995

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26891032, KAKENHI-PROJECT-15K06980
  • [Journal Article] Putting things in place for fertilization: Discovering roles for importin proteins in cell fate and spermatogenesis2015

    • Author(s)
      Loveland KL., Major A., Butler R., Young J., Jans DA., Miyamoto Y.
    • Journal Title

      Asian Journal of Andrology

      Volume: 17 Issue: 4 Pages: 1-8

    • DOI

      10.4103/1008-682x.154310

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26891032
  • [Journal Article] Functional Dynamics of Importin α family2015

    • Author(s)
      宮本洋一、盛山哲嗣
    • Journal Title

      生化学

      Volume: 87 Issue: 1 Pages: 16-21

    • DOI

      10.14952/SEIKAGAKU.2015.870016

    • ISSN
      0037-1017
    • Year and Date
      2015-02-25
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-26891032
  • [Journal Article] Specific interaction with the nuclear transporter importin α2 can modulate paraspeckle protein 1 delivery to nuclear paraspeckles2015

    • Author(s)
      Major A.T., Hogarth C.A., Miyamoto Y., Sarraj M.A., Smith C.L., Koopman P., Kurihara Y., Jans D.A., Loveland K.L.
    • Journal Title

      Mol. Biol. Cell

      Volume: 26 Issue: 8 Pages: 1543-1558

    • DOI

      10.1091/mbc.e14-01-0678

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26891032
  • [Journal Article] Functional characterization of importin α8 as a classical nuclear localization signal receptor2015

    • Author(s)
      Kimoto C., Moriyama T., Tsujii A., IgarashiY., Obuse C., Miyamoto Y., Oka M., Yoneda Y.
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

      Volume: 1853 Issue: 10 Pages: 2676-2683

    • DOI

      10.1016/j.bbamcr.2015.07.017

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07068, KAKENHI-PROJECT-26650002, KAKENHI-PROJECT-26870341, KAKENHI-PLANNED-25116004, KAKENHI-PLANNED-25116008
  • [Journal Article] 創薬ターゲットとしての核-細胞質間物質輸送2015

    • Author(s)
      宮本洋一
    • Journal Title

      バイオサイエンス&インダストリー

      Volume: 73 Pages: 288-291

    • NAID

      40020536325

    • Data Source
      KAKENHI-PROJECT-15K07068
  • [Patent] フラビウイルス感染に対する抗ウイルス治療2018

    • Inventor(s)
      宮本洋一 他
    • Industrial Property Rights Holder
      宮本洋一 他
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-101399
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16H04789
  • [Patent] 精神疾患モデル動物およびその製造方法2017

    • Inventor(s)
      岡正啓、盛山哲嗣、米田悦啓、宮本洋一、辻井聡、疋田貴俊、森田
    • Industrial Property Rights Holder
      岡正啓、盛山哲嗣、米田悦啓、宮本洋一、辻井聡、疋田貴俊、森田
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-026027
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-15K07068
  • [Presentation] A novel functional aspect of Importin α in micronuclei2024

    • Author(s)
      Miyamoto Y., Saitoh H. Oka M.
    • Organizer
      RIKEN International Symposium on Nuclear Structure and Function 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KK0111
  • [Presentation] 核輸送分子Importin α1が微小核に局在する生理的意義の解明2023

    • Author(s)
      宮本洋一, 木佐貫玲央, 大背戸里詠子, 斉藤寿仁, 岡正啓
    • Organizer
      第96回日本生化学会
    • Data Source
      KAKENHI-PROJECT-22KK0111
  • [Presentation] 核輸送分子Importin-αの多機能性と微小核機能2023

    • Author(s)
      宮本洋一, 木佐貫玲央, 斉藤寿仁, 岡正啓
    • Organizer
      第46回日本分子生物学会シンポジウム
    • Data Source
      KAKENHI-PROJECT-22KK0111
  • [Presentation] Importins in Reproduction2023

    • Author(s)
      Yoichi Miyamoto
    • Organizer
      Hudson Institute of Medial Research Centre for Reproductive Health special seminor
    • Invited
    • Data Source
      KAKENHI-PROJECT-22KK0111
  • [Presentation] Importin α and micronucleus2023

    • Author(s)
      Miyamoto Y.
    • Organizer
      Hudson Institute of Medial Research Centre for Reproductive Health Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KK0111
  • [Presentation] 新規微小核マーカーとしてのインポーティンα1の同定と解析2023

    • Author(s)
      宮本洋一, 斉藤寿仁, 岡正啓
    • Organizer
      第45回蛋白質と酵素の構造と機能に関する九州シンポジウム
    • Data Source
      KAKENHI-PROJECT-22KK0111
  • [Presentation] Importin α4 is critical for establishing normal sperm morphology in mice2023

    • Author(s)
      Miyamoto Y., Okada Y., Loveland KL., Oka M.
    • Organizer
      ESA-SRB 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22KK0111
  • [Presentation] 核輸送分子の微小核局在に関する研究2023

    • Author(s)
      宮本洋一, 斉藤寿仁, 岡正啓
    • Organizer
      2022年度生物機能研究会
    • Data Source
      KAKENHI-PROJECT-22KK0111
  • [Presentation] Importins in Reproduction2023

    • Author(s)
      Yoichi Miyamoto
    • Organizer
      Hudson Institute of Medial Research Centre for Reproductive Health special seminor
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K06455
  • [Presentation] 核輸送分子の微小核局在に関する研究2022

    • Author(s)
      宮本洋一, 斉藤寿仁, 岡正啓
    • Organizer
      生物機能研究会
    • Data Source
      KAKENHI-PROJECT-20K06455
  • [Presentation] Importin αの微小核への分子濃縮2022

    • Author(s)
      木佐貫玲央, 宮本洋一, 岡正啓, 斉藤寿仁
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-20K06455
  • [Presentation] SARS-CoV-2構成因子ORF6による核輸送制御機構2021

    • Author(s)
      宮本洋一, 伊東祐美, 鈴木達也, 田中智久, 坂井祐介, 小井土大, 波田千彰, 王彩霞, 大谷真弓, 森石恆司, 立花太郎, 鎌谷洋一郎, 米田悦啓, 岡本徹, 岡正啓
    • Organizer
      第73回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-20K06455
  • [Presentation] importin α5は統合失調症の環境因子暴露への影響を変動させる2021

    • Author(s)
      野宮廣貴, 疋田貴俊, 宮本洋一, 岡正啓, 山田雅巳
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K06455
  • [Presentation] Importin alpha 5(KPNA1)の神経細胞内における新規機能的役割の解明2021

    • Author(s)
      菅原将樹, 水野克俊, 山口楓香, 加藤諒大, 野宮廣貴, 宮本洋一, 岡正啓, 疋田貴俊, 藤田聡, 山田雅巳
    • Organizer
      第73回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-20K06455
  • [Presentation] インポーティンαの微小核への分子濃縮現象:染色体不安定性とゲノム進化へのインポーティンαの寄与を考える2021

    • Author(s)
      木佐貫玲央, 宮本洋一, 斉藤寿仁
    • Organizer
      第39回染色体ワークショップ・第20回核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-20K06455
  • [Presentation] 核小体形成を標的とした抗フラビウイルス薬の同定2020

    • Author(s)
      宮本洋一、德永詢、鈴木達也、大谷真弓、井貫晋輔、江崎剛史、長尾 知生子、水口賢司、大野浩章、米田悦啓、岡本徹、松浦善治、岡正啓
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-20K06455
  • [Presentation] KPNA1の軸索輸送における機能的役割の解明2020

    • Author(s)
      菅原将樹, 水野克俊, 山口楓香, 野宮廣貴, 宮本洋一, 岡正啓, 疋田貴俊, 藤田聡, 山田雅己
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-20K06455
  • [Presentation] 核輸送因子Kpna1ノックアウトマウスにおける行動異常の環境による増悪2020

    • Author(s)
      櫻井航輝、 宮本洋一、 盛山哲嗣、 森田真規子、伊藤大一、岡正啓、疋田貴俊
    • Organizer
      日本神経科学会
    • Data Source
      KAKENHI-PROJECT-20K06455
  • [Presentation] 統合失調症関連症状を示す核輸送分子importin α4ノックアウトマウスの解析2018

    • Author(s)
      宮本洋一、伊藤大一、森田真規子、永井理博、盛山哲嗣、Kate L. Loveland、米田悦啓、疋田貴俊、岡正啓
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H04789
  • [Presentation] The nuclear transport factor importin α4 is involved in normal male fertility and brain development in mouse.2018

    • Author(s)
      Miyamoto Y, Itou T, Morita M, Nagai M, Sasaki M, Moriyama T, Loveland KL, Yoneda Y, Hikida T, Oka M.
    • Organizer
      第70回日本細胞生物学会
    • Data Source
      KAKENHI-PROJECT-16H04789
  • [Presentation] 統合失調症関連症状を示す核輸送分子importin α4ノックアウトマウスの解析2018

    • Author(s)
      宮本洋一、伊藤大一、森田真規子、永井理博、盛山哲嗣、Kate L. Loveland、米田悦啓、疋田貴俊、岡正啓
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16H04789
  • [Presentation] The role of Crm1, a nuclear export receptor, in the regulation of gene expression.2018

    • Author(s)
      Oka M, Mura S, Miyamoto Y, Ohkawa Y, Kimura H, Yoneda Y.
    • Organizer
      第70回日本細胞生物学会
    • Data Source
      KAKENHI-PROJECT-16H04789
  • [Presentation] 生殖細胞形成とストレス応答におけるSTK35L1の役割2017

    • Author(s)
      宮本洋一、Penny A.F. Whiley、岡正啓、Kate L. Loveland
    • Organizer
      日本細胞生物学会
    • Data Source
      KAKENHI-PROJECT-15K07068
  • [Presentation] 細胞外放出されるimportinα1の生物活性の解析2016

    • Author(s)
      生野雄大、山田幸司、宮本洋一、米田悦啓、岡正啓
    • Organizer
      第68回日本細胞生物学会大会
    • Place of Presentation
      京都
    • Year and Date
      2016-06-15
    • Data Source
      KAKENHI-PROJECT-16H04789
  • [Presentation] Novel function of nuclear transport factor in cancer <cell surface localization of importin α1 affects cancer cell prokiferation by regulating FGF 1 signalling>2016

    • Author(s)
      山田幸司、宮本洋一、岡正啓、米田悦啓
    • Organizer
      第41回内藤コンファレンス
    • Place of Presentation
      札幌
    • Year and Date
      2016-07-05
    • Data Source
      KAKENHI-PROJECT-16H04789
  • [Presentation] Regulation mechanism of a classical nuclear protein transport through importin α2015

    • Author(s)
      Yoichi Miyamoto
    • Organizer
      International Symposium on Biomolecular Sciences
    • Place of Presentation
      宮崎
    • Year and Date
      2015-12-17
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07068
  • [Presentation] 新規核局在化シグナル受容体importin α8の機能解析2015

    • Author(s)
      宮本洋一、盛山哲嗣、木本千裕、辻井聡、五十嵐芳暢、小布施力史、岡正啓、米田悦啓
    • Organizer
      BMB2015
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K07068
  • [Presentation] A novel regulator of a classical nuclear transport pathway and cellular senescence2015

    • Author(s)
      Yoichi Miyamoto
    • Organizer
      Nuclear Transport Meeting
    • Place of Presentation
      スペイン
    • Year and Date
      2015-09-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07068
  • [Presentation] 細胞ストレスと精子形成を制御するImportin αの機能2014

    • Author(s)
      宮本洋一
    • Organizer
      理研セミナー
    • Place of Presentation
      埼玉
    • Year and Date
      2014-09-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26891032
  • [Presentation] 精製精子細胞を用いたインポーティンα結合分子の同定とその解析

    • Author(s)
      宮本洋一, Arjomand A., Baker M.A., Li C., Buckle A.M., Jans D.A., Loveland K.L.
    • Organizer
      日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26891032
  • [Presentation] 核内輸送因子Importin αとヒストン結合タンパクRBBP4の非典型的結合

    • Author(s)
      辻井聡、宮本洋一、盛山哲嗣、岡正啓、米田悦啓
    • Organizer
      日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26891032
  • [Presentation] STK35は生殖器と眼の発生およびストレス応答に重要である

    • Author(s)
      宮本洋一, Whiley P.A.W., Goh H.Y., Wong C., Higgins G., 立花太郎, McMenamin P., Mayne L., Loveland K.L.
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-26891032
  • [Presentation] 核内輸送因子Importin αとヒストン結合タンパクRBBP4の非典型的結合とその結合意義

    • Author(s)
      辻井聡、宮本洋一、盛山哲嗣、岡正啓、米田悦啓
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-26891032
  • 1.  TOMONAGA Takeshi (80227644)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  OKA Masahiro (40432504)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 18 results
  • 3.  YONEDA Yoshihiro (80191667)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 4.  FUJII Satoshi (30314743)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SHIROMIZU Takashi (00582678)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  YAMADA Kohji (90570979)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  MORIYAMA Tetsuji (50627990)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  HIKIDA Takatoshi (70421378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 9.  TORU OKAMOTO (80628595)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  奥崎 大介 (00346131)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  岡田 由紀 (60546430)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  原 聡史 (80739582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  小井土 大 (40787561)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  小澤 貴明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 15.  松浦 善治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  河岡 義裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  鈴木 信弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  長竹 貴広
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  齊藤 暁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi