ASAI KAZUHISA 浅井一久

… Alternative Names

浅井一久アサイカズヒサ

Asai Kazuhisa 浅井一久

ASAI Kazuhisa 浅井一久

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Researcher Number	10382053
Other IDs
Affiliation (Current)	2025: 大阪公立大学, 大学院医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2023: 大阪公立大学, 大学院医学研究科, 准教授 2019 – 2021: 大阪市立大学, 大学院医学研究科, 准教授 2015 – 2017: 大阪市立大学, 大学院医学研究科, 講師 2012 – 2013: 大阪市立大学, 医学(系)研究科(研究院), 病院講師 2010: Osaka City University, 大学院・医学研究科, 研究員 2009 – 2010: Osaka City University, 大学院・医学研究科, 病院講師
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related Except Principal Investigator Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator COPD / 慢性閉塞性肺疾患 / 気道炎症 / 閉塞性肺疾患 / バルドキソロンメチル / マイオカイン / アイリシン / バルドキソロン / タバコ / Nrf2 … More / PTEN / PI3K / 酸化ストレス / メタボリックシンドローム / 免疫学 / アレルギー・喘息 / アディポサイトカイン / 肥満 / 気管支喘息 … More Except Principal Investigator 慢性閉塞性肺疾患 / 筋肉関連遺伝子多型 / サルコペニア / 身体活動性 / COPD Less

慢性閉塞性肺疾患における筋肉関連遺伝子多型を加味した新規治療戦略に関する検討
- Principal Investigator
  
  渡辺徹也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Osaka Metropolitan University
Mechanism of emphysema formation by controlling the Keap1-Nrf2 system and its application to COPD treatment strategiesPrincipal Investigator
- Principal Investigator
  
  ASAI KAZUHISA
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Osaka City University
PI3K-PTEN imbalance is a potential new therapeutic target in COPDPrincipal Investigator
- Principal Investigator
  
  Asai Kazuhisa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka City University
Regulation of transcription factor in airway epithelial cells for asthma treatmentPrincipal Investigator
- Principal Investigator
  
  ASAI KAZUHISA
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka City University
Adipocytokine as an exacerbation factor for asthma and its possible involvement in therapeutic target for asthmaPrincipal Investigator
- Principal Investigator
  
  ASAI Kazuhisa
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka City University

[Book] 呼吸器疾患-state of arts Ver.6(第4章)主要疾患病態・診断・治療アレルギー性肺疾患アレルギー性気管支肺アスペルギルス症医学のあゆみ別冊呼吸器疾患- state of arts Ver.62013
- Author(s)
  浅井一久,平田一人
- Total Pages
  520
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-24790818
[Book] 医学のあゆみ別冊呼吸器疾患-state of arts Ver.62013
- Author(s)
  浅井一久, 平田一人, 青柴和徹, 秋山一男, 浅井信博, 浅野浩一郎, 吾妻安良太, 荒屋　潤, 生島壮一郎, 池田徳彦, 石井　寛, 石崎武志, 石原陽子, 石本裕士, 伊藤正明, 稲瀬直彦, 井上　彰, 井上博雅, 井上義一, 今岡治樹
- Total Pages
  520
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-24790818
[Book] 最新医学別冊「新しい診断と治療のABC」呼吸器2 喘息(改訂第2版)2011
- Author(s)
  浅井一久, 平田一人
- Publisher
  最新医学社(印刷中)
- Data Source
  KAKENHI-PROJECT-21790779
[Book] 最新医学別冊「新しい診断と治療のABC」呼吸器2喘息(改訂第2版)(第4章管理・治療薬物療法・選択基準)2011
- Author(s)
  浅井一久, 平田一人
- Publisher
  (共著、印刷中)
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] Safety profile and risk factors for bleeding in transbronchial cryobiopsy using a two-scope technique for peripheral pulmonary lesions2022
- Author(s)
  Nakai Toshiyuki、Watanabe Tetsuya、Kaimi Yuto、Ogawa Koichi、Matsumoto Yoshiya、Sawa Kenji、Okamoto Atsuko、Sato Kanako、Asai Kazuhisa、Matsumoto Yuji、Ohsawa Masahiko、Kawaguchi Tomoya
- Journal Title
  
  BMC Pulmonary Medicine
  
  Volume: 22 Issue: 1 Pages: 20-20
- DOI
  10.1186/s12890-021-01817-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08660
[Journal Article] Tumor microenvironment disparity in multiple primary lung cancers: Impact of non-intrinsic factors, histological subtypes, and genetic aberrations2021
- Author(s)
  Izumi Motohiro、Sawa Kenji、Oyanagi Jun、Noura Ikue、Fukui Mitsuru、Ogawa Koichi、Matsumoto Yoshiya、Tani Yoko、Suzumura Tomohiro、Watanabe Tetsuya、Kaneda Hiroyasu、Mitsuoka Shigeki、Asai Kazuhisa、Nishiyama Noritoshi、Ohsawa Masahiko、Yamamoto Nobuyuki、Koh Yasuhiro、Kawaguchi Tomoya
- Journal Title
  
  Translational Oncology
  
  Volume: 14 Issue: 7 Pages: 101102-101102
- DOI
  10.1016/j.tranon.2021.101102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08660
[Journal Article] Phase II Study of the Modified Weekly Nab-paclitaxel Regimen in Previously Treated Patients With Advanced Non?Small Cell Lung Cancer2021
- Author(s)
  Yoshimura Naruo、Sawa Kenji、Nakai Toshiyuki、Matsumoto Yoshiya、Mitsuoka Shigeki、Kimura Tatsuo、Asai Kazuhisa、Yana Takashi、Kawaguchi Tomoya、Hirata Kazuto
- Journal Title
  
  American Journal of Clinical Oncology
  
  Volume: 44 Issue: 12 Pages: 613-618
- DOI
  10.1097/coc.0000000000000876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08660
[Journal Article] 【COPD患者における栄養管理のポイント】COPDにおけるサルコペニア・フレイル2020
- Author(s)
  浅井一久
- Journal Title
  
  臨床栄養
  
  Volume: 136 Pages: 990-996
- Data Source
  KAKENHI-PROJECT-19K08660
[Journal Article] Exercise Ameliorates Emphysema Of Cigarette Smoke-Induced COPD In Mice Through The Exercise-Irisin-Nrf2 Axis.2019
- Author(s)
  Kubo H, Asai K, Kojima K, Sugitani A, Kyomoto Y, Okamoto A, Yamada K, Ijiri N, Watanabe T, Hirata K, Kawaguchi T.
- Journal Title
  
  International Journal of COPD
  
  Volume: 14 Pages: 2507-2516
- DOI
  10.2147/copd.s226623
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08660, KAKENHI-PROJECT-17K07176
[Journal Article] Astaxanthin Suppresses Cigarette Smoke-Induced Emphysema through Nrf2 Activation in Mice.2019
- Author(s)
  Kubo H, Asai K, Kojima K, Sugitani A, Kyomoto Y, Okamoto A, Yamada K, Ijiri N, Watanabe T, Hirata K, Kawaguchi T.
- Journal Title
  
  Marine Drugs
  
  Volume: 17 Issue: 12 Pages: 673-673
- DOI
  10.3390/md17120673
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08660, KAKENHI-PROJECT-17K07176
[Journal Article] Correlation between disease activity and serum ferritin in clinically amyopathic dermatomyositis with rapidly-progressive interstitial lung disease: a case report2018
- Author(s)
  Yamada Kazuhiro、Asai Kazuhisa、Okamoto Atsuko、Watanabe Tetsuya、Kanazawa Hiroshi、Ohata Mai、Ohsawa Masahiko、Hirata Kazuto
- Journal Title
  
  BMC Res Notes
  
  Volume: 11 Issue: 1 Pages: 1-2
- DOI
  10.1186/s13104-018-3146-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] PIK3CA mutation as a distinctive genetic feature of non-small cell lung cancer with chronic obstructive pulmonary disease: A comprehensive mutational analysis from a multi-institutional cohort2017
- Author(s)
  Sawa Kenji、Koh Yasuhiro、Kawaguchi Tomoya、Kambayashi Satoshi、Asai Kazuhisa、Mitsuoka Shigeki、Kimura Tatsuo、Yoshimura Naruo、Yoshimoto Naoki、Kubo Akihito、Saka Hideo、Matsumura Akihide、Wanibuchi Hideki、Yamamoto Nobuyuki、Nishiyama Noritoshi、Hirata Kazuto
- Journal Title
  
  Lung Cancer
  
  Volume: 112 Pages: 96-101
- DOI
  10.1016/j.lungcan.2017.07.039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07128, KAKENHI-PROJECT-17K07176, KAKENHI-PROJECT-17K09162, KAKENHI-PROJECT-15K06878, KAKENHI-PROJECT-15K09185, KAKENHI-PROJECT-15K09226
[Journal Article] Decreased levels of irisin, a skeletal muscle cell-derived myokine, are related to emphysema associated with chronic obstructive pulmonary disease.2017
- Author(s)
  Sugiyama Y, Asai K, Yamada K, Kureya Y, Ijiri N, Watanabe T, Kanazawa H, Hirata K
- Journal Title
  
  International Journal of Chronic Obstructive Pulmonary Disease
  
  Volume: 12 Pages: 765-772
- NAID
  120006330653
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] Atrial natriuretic peptide protects against bleomycin-induced pulmonary fibrosis via vascular endothelial cells in mice : ANP for pulmonary fibrosis.2017
- Author(s)
  Okamoto A, Nojiri T, Konishi K, Tokudome T, Miura K, Hosoda H, Hino J, Miyazato M, Kyomoto Y, Asai K, Hirata K, Kangawa K
- Journal Title
  
  Respir Res
  
  Volume: 18 Issue: 1 Pages: 1-1
- DOI
  10.1186/s12931-016-0492-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05306, KAKENHI-PROJECT-26461393, KAKENHI-PROJECT-15K09185, KAKENHI-PROJECT-16K10700
[Journal Article] Decreased levels of irisin, a skeletal muscle cell-derived myokine, are related to emphysema associated with chronic obstructive pulmonary disease.2017
- Author(s)
  Yukari Sugiyama、Kazuhisa Asai、Kazuhiro Yamada、Yuko Kureya、Naoki Ijiri、Tetsuya Watanabe、Hiroshi Kanazawa、Kazuto Hirata
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis.
  
  Volume: 12 Pages: 765-772
- NAID
  120006330653
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] Down-Regulation of Soluble α-Klotho is Associated with Reduction in Serum Irisin Levels in Chronic Obstructive Pulmonary Disease.2016
- Author(s)
  Kureya Y, Kanazawa H, Ijiri N, Tochino Y, Watanabe T, Asai K, Hirata K.
- Journal Title
  
  Lung.
  
  Volume: 194 Issue: 3 Pages: 345-351
- DOI
  10.1007/s00408-016-9870-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] Impaired nuclear factor erythroid 2-related factor 2 expression increases apoptosis of airway epithelial cells in patients with chronic obstructive pulmonary disease due to cigarette smoking.2016
- Author(s)
  Yamada K, Asai K, Nagayasu F, Sato K, Ijiri N, Yoshii N, Imahashi Y, Watanabe T, Tochino Y, Kanazawa H, Hirata K.
- Journal Title
  
  BMC Pulm Med.
  
  Volume: 16 Issue: 1 Pages: 27-27
- DOI
  10.1186/s12890-016-0189-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] An Intrinsic Strain of Colistin-resistant <i>Acinetobacter</i> Isolated from a Japanese Patient2016
- Author(s)
  Takizawa E., Yamada K., Oinuma K., Sato K., Niki M., Namikawa H., Fujimoto H., Asai K., Kaneko Y. and Kakeya H.
- Journal Title
  
  Intern. Med.
  
  Volume: 55 Issue: 16 Pages: 2301-2306
- DOI
  10.2169/internalmedicine.55.6807
- NAID
  130005169382
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26850060, KAKENHI-PROJECT-15K09185
[Journal Article] Efficacy and safety of indacaterol/glycopyrronium in Japanese patients with COPD: Pooled analysis of SHINE and ARISE.2016
- Author(s)
  Asai K, Hirata K, Hashimoto S, Fukuchi Y, Kitawaki T, Ikeda K, Fogel R, Banerji D.
- Journal Title
  
  Respir Investig.
  
  Volume: 54 Issue: 6 Pages: 428-435
- DOI
  10.1016/j.resinv.2016.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] Epidermal growth factor receptor tyrosine kinase inhibitors in previously treated advanced non-small-cell lung cancer with wild-type EGFR.2016
- Author(s)
  Mitsuoka S, Kawaguchi T, Kubo A, Isa S, Asai K, Uji M, Watanabe T, Sawa K, Yoshimoto N, Oka T, Nakai T, Suzumura T, Tanaka H, Matsuura K, Kimura T, Yoshimura N, Kudoh S, Hirata K.
- Journal Title
  
  Expert Opin Pharmacother.
  
  Volume: 17 Issue: 2 Pages: 193-203
- DOI
  10.1517/14656566.2016.1109635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] Irisin, a newly discovered myokine, is a novel biomarker associated with physical activity in patients with chronic obstructive pulmonary disease.2015
- Author(s)
  Ijiri N, Kanazawa H, Asai K, Watanabe T, Hirata K.
- Journal Title
  
  Respirology
  
  Volume: 20 Issue: 4 Pages: 612-617
- DOI
  10.1111/resp.12513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] The Macroscopic Appearance of Computed Tomography-guided Needle Biopsy Specimens Correlates with Tumor Metastasis in Non-small Cell Lung Cancer.2015
- Author(s)
  Toshiyuki N, Kimura T, Suzumura T, Yoshimoto N, Oka T, Yamamoto N, Matsuura K, Mitsuoka S, Asai K, Tochino Y, Yoshimura N, Kawaguchi T, Kudoh S, Matsuoka T, Ohsawa M, Hirata K.
- Journal Title
  
  Osaka City Med J.
  
  Volume: 61 Pages: 105-112
- NAID
  120006493307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] Phase II study of a combination regimen of gefitinib and pemetrexed as first-line treatment in patients with advanced non-small cell lung cancer harboring a sensitive EGFR mutation.2015
- Author(s)
  Yoshimura N, Kudoh S, Mitsuoka S, Yoshimoto N, Oka T, Nakai T, Suzumira T, Matusura K, Tochino Y, Asai K, Kimura T, Kawaguchi T, Hirata K.
- Journal Title
  
  Lung Cancer
  
  Volume: 90 Issue: 1 Pages: 65-70
- DOI
  10.1016/j.lungcan.2015.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] Primary Pleural Synovial Sarcoma Treated with Pazopanib2015
- Author(s)
  Sugitani A, Asai K, Kojima K, Eguchi Y, Kawaguchi T, Ohsawa M, Hirata K.
- Journal Title
  
  Intern. Med.
  
  Volume: 54 Issue: 16 Pages: 2051-2055
- DOI
  10.2169/internalmedicine.54.3570
- NAID
  130005092891
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] Pentraxin-3 as a Biomarker for Febrile Neutropenia in Patients with Lung Cancer.2015
- Author(s)
  Takeda N, Asai K, Ijiri N, Yamamoto N, Watanabe T, Kamoi H, Kanazawa H, Hirata K.
- Journal Title
  
  Osaka City Med J.
  
  Volume: 61 Pages: 43-52
- NAID
  120006493313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09185
[Journal Article] Potential role of pentosidine on susceptibility to small airway closure in elderly and smoking asthma2014
- Author(s)
  Kanazawa H, Kyoh S, Tochino Y, Asai K, Hirata K
- Journal Title
  
  Respir Med
  
  Volume: 108(5) Pages: 709-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] 【段階に応じたCOPD薬物治療】労作時の呼吸困難2014
- Author(s)
  平田一人,栩野吉弘,浅井一久
- Journal Title
  
  日本医事新報
  
  Volume: 4681号 Pages: 29-34
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] 【COPD治療の新時代21世紀の「社会的」生活習慣病】知っておくべき日本のCOPD治療のエビデンスBAREC研究2014
- Author(s)
  平田一人,浅井一久
- Journal Title
  
  内科
  
  Volume: 113巻2号 Pages: 321-324
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] Potential role of pentosidine on susceptibility to small airway closure in elderly and smoking asthma.2014
- Author(s)
  Kanazawa H, Kyoh S, Tochino Y, Asai K, Hirata K
- Journal Title
  
  Respiratory Medicine
  
  Volume: 108巻 Issue: 5 Pages: 709-715
- DOI
  10.1016/j.rmed.2014.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] 【COPD-その病態と最新治療】日本のガイドラインとGOLD2013
- Author(s)
  平田一人,栩野吉弘,浅井一久
- Journal Title
  
  カレントテラピー
  
  Volume: 31巻5号 Pages: 473-479
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] 【日本呼吸器学会 COPDガイドライン第4版をめぐって】増悪期の管理・予後・病診連携2013
- Author(s)
  平田一人,栩野吉弘,浅井一久
- Journal Title
  
  日本胸部臨床
  
  Volume: 72巻11号 Pages: 1228-1238
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] 【呼吸器疾患の増悪を考える】COPD増悪時の治療と予後2013
- Author(s)
  平田一人,栩野吉弘,浅井一久
- Journal Title
  
  THE LUNG perspectives
  
  Volume: 21巻3号 Pages: 262-266
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] 【新たな展開を見せる COPD治療と新治療薬オーキシスへの期待】COPD増悪治療戦略2013
- Author(s)
  平田一人,栩野吉弘,浅井一久
- Journal Title
  
  吸入療法
  
  Volume: 5巻2号 Pages: 46-54
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] 【気管支喘息:診断と治療の進歩】概念　COPDとの鑑別と併存2013
- Author(s)
  栩野吉弘, 浅井一久, 平田一人
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 102巻 Pages: 1352-1358
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] 【気管支喘息 : 診断と治療の進歩】概念COPDとの鑑別と併存2013
- Author(s)
  栩野吉弘,浅井一久,平田一人
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 102巻6号 Pages: 1352-1358
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] 【喘息病態の修飾因子・難治化因子】喫煙2013
- Author(s)
  浅井一久,平田一人
- Journal Title
  
  呼吸と循環
  
  Volume: 61巻6号 Pages: 523-528
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] 【COPD治療のキーポイント】治療吸入ステロイド(配合薬を含む)2013
- Author(s)
  平田一人,栩野吉弘,浅井一久
- Journal Title
  
  Mebio
  
  Volume: 30巻5号 Pages: 58-69
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] 【喘息病態の修飾因子・難治化因子】喫煙2013
- Author(s)
  浅井一久, 平田一人
- Journal Title
  
  呼吸と循環
  
  Volume: 61巻 Pages: 523-528
- Data Source
  KAKENHI-PROJECT-24790818
[Journal Article] Increased levels of HMGB-1 and endogenous secretory RAGE in induced sputum from asthmatic patients.2011
- Author(s)
  Watanabe T, Asai K, Fujimoto H, Tanaka H, Kanazawa H, Hirata K
- Journal Title
  
  Respiratory Medicine
  
  Volume: 105 Pages: 519-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] Potential roles of pentosidine in age-related and disease-related impairment of pulmonary functions in patients with asthma.2011
- Author(s)
  Kanazawa H, Tochino Y, Kyoh S, Ichimaru Y, Asai K, Hirata K.
- Journal Title
  
  J Allergy Clin Immunol. (in press).
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] Increased levels of HMGB-1 and endogenous secretory RAGE in induced sputum from asthmatic patients.2011
- Author(s)
  Watanabe T, Asai K, Fujimoto H, Tanaka H, Kanazawa H, Hirata K.
- Journal Title
  
  Respir Med. 105(4)
  
  Pages: 519-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] Validity of measurement of two specific biomarkers for the assessment of small airways inflammation in asthma.2010
- Author(s)
  Kanazawa H, Kyoh S, Asai K, Hirata K.
- Journal Title
  
  J Asthma. 47(4)
  
  Pages: 400-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] 喫煙とCOPD2010
- Author(s)
  平田一人, 浅井一久
- Journal Title
  
  喫煙が気管支拡張薬に及ぼす影響呼吸器内科 17巻5号
  
  Pages: 450-455
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] 呼吸不全の実地診療治療ストラテジーの新たな展開2010
- Author(s)
  平田一人, 浅井一久
- Journal Title
  
  呼吸不全の実地診療・セミナー/呼吸不全をきたす疾患の実地診療のポイント気管支喘息急性期から慢性期のアプローチの実際Medical Practice 27巻4
  
  Pages: 633-639
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] 咳の新しい捉え方2010
- Author(s)
  平田一人, 浅井一久
- Journal Title
  
  COPD成人病と生活習慣病 40巻11号
  
  Pages: 1285-1290
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] 吸入療法の新展開吸入去痰薬の新しい動向2010
- Author(s)
  浅井一久, 平田一人
- Journal Title
  
  吸入療法 2巻1号
  
  Pages: 74-81
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] 増加するアレルギー疾患内科医にとっての最良のアプローチとは2010
- Author(s)
  平田一人, 浅井一久
- Journal Title
  
  成人喘息への理解と対応合併病態への対応COPDと喘息の合併内科 105巻4号
  
  Pages: 644-649
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] Increased levels of N(epsilon)-(carboxymethyl)lysine in epithelial lining fluid from peripheral airways in patients with chronic obstructive pulmonary disease : a pilot study.2010
- Author(s)
  Kanazawa H, Kodama T, Asai K, Matsumura S, Hirata K.
- Journal Title
  
  Clin Sci (Lond). 119(3)
  
  Pages: 143-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] 呼吸不全の実地診療治療ストラテジーの新たな展開2010
- Author(s)
  平田一人, 浅井一久
- Journal Title
  
  呼吸不全の実地診療・セミナー/呼吸不全をきたす疾患の実地診療のポイント気管支喘息急性期から慢性期のアプローチの実際Medical Practice 27巻4号
  
  Pages: 633-639
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] 喘息とCOPDをめぐって類似点と相違点2010
- Author(s)
  平田一人, 浅井一久
- Journal Title
  
  治療ステロイドの効果の差アレルギー・免疫 17巻12号
  
  Pages: 2034-2042
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] Validity of measurement of two specific biomarkers for the assessment of small airways inflammation in asthma.2010
- Author(s)
  Kanazawa H, Kyoh S, Asai K, Hirata K
- Journal Title
  
  Journal of Asthma
  
  Volume: 47 Pages: 400-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] 末梢気道をめぐって2009
- Author(s)
  平田一人, 浅井一久
- Journal Title
  
  末梢気道障害が関与する呼吸器疾患(喘息を除く)アレルギー・免疫 17巻1号
  
  Pages: 30-35
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] 最新のCOPD治療大規模臨床試験の結果から2009
- Author(s)
  平田一人, 浅井一久
- Journal Title
  
  COPDにおける早期治療介入の有用性を示したチオトロピウムの長期大規模臨床試験UPLIFT Study医学のあゆみ 231巻4号
  
  Pages: 271-276
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] Increased levels of angiopoietin-2 in induced sputum from smoking asthmatic patients.2009
- Author(s)
  Kanazawa H, Asai K, Tochino Y, Kyoh S, Kodama T, Hirata K.
- Journal Title
  
  Clin Exp Allergy. 39(9)
  
  Pages: 1330-1337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] 咳嗽そのcommonで多様な疾患領域2009
- Author(s)
  平田一人, 浅井一久
- Journal Title
  
  咳嗽の治療綜合臨床 58巻10号
  
  Pages: 2067-2071
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] Potential mechanisms of airway remodeling initiated by activated thrombin in asthma.2009
- Author(s)
  Kanazawa H, Kyoh S, Tochino Y, Kodama T, Asai K, Hirata K.
- Journal Title
  
  Arerugi.(Japanese.) 58(5)
  
  Pages: 554-559
- NAID
  110007337983
- Data Source
  KAKENHI-PROJECT-21790779
[Journal Article] Potential roles of pentosidine in age-related and disease-related impairment of pulmonary functions in patients with asthma.
- Author(s)
  Kanazawa H, Tochino Y, Kyoh S, Ichimaru Y, Asai K, Hirata K
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790779
[Presentation] 骨格筋バイオロジーからみた身体活動性の重要性2022
- Author(s)
  浅井一久
- Organizer
  第62回日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08660
[Presentation] 喘息モデルマウスにおけるImmuBalanceの好酸球性炎症抑制効果の検討2022
- Author(s)
  門谷英昭、浅井一久、小林正典、山根健志、宮本篤志、岩﨑剛平、川井隆広、西村美沙子、豊蔵恵里佳、東田充功、岡本敦子、佐藤佳奈子、井尻尚樹、渡辺徹也、金澤博、川口知哉、平田一人
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08660
[Presentation] 骨格筋のバイオロジーからみた身体活動性の重要性2021
- Author(s)
  浅井一久
- Organizer
  第30回日本呼吸ケア・リハビリテーション学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08660
[Presentation] COPDモデルマウスにおいて人参養栄湯は骨格筋合併症を改善する2021
- Author(s)
  宮本篤志、浅井一久、門谷英昭、丸山直美、久保寛明、岡本敦子、佐藤佳奈子、井尻尚樹、渡辺徹也、川口知哉
- Organizer
  第61回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08660
[Presentation] Ninjin-yoeito ameliorates cigarette smoke-induced skeletal muscle complications in mice.2020
- Author(s)
  A. Miyamoto, H. Kadotani, K. Asai, N. Maruyama, H. Kubo, A. Okamoto, N. Ijiri, K. Sato, T. Watanabe, K. Hirata, T. Kawaguchi
- Organizer
  ERS International Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08660
[Presentation] Astaxanthin Suppresses Cigarette Smoke-Induced Emphysema Through Nrf2 Activation in Mice.2020
- Author(s)
  H. Kubo , K. Asai , K. Iwasaki , T. Kawai , M. Nishimura , N. Maruyama , H. Kadotani , A. Miyamoto , A. Okamoto , K. Sato , K. Yamada , N. Ijiri , T. Watanabe , K. Hirata , T. Kawaguchi
- Organizer
  ATS 2020 International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08660
[Presentation] CSE刺激時にLong non coding RNA:NEAT1は炎症性サイトカインの放出を促す2020
- Author(s)
  井尻尚樹, 浅井一久, 佐藤佳奈子, 山田一宏, 山本典雄, 渡辺徹也, 金澤博, 平田一人, 川口知哉
- Organizer
  第60回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08660
[Presentation] 喫煙曝露COPDマウスにおけるアスタキサンチンのCOPD抑制効果の検討2020
- Author(s)
  久保寛明, 浅井一久, 小島和也, 杉谷新, 門谷英昭, 宮本篤志, 丸山直美, 岡本敦子, 渡辺徹也, 金澤博, 川口知哉, 平田一人
- Organizer
  第60回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K08660
[Presentation] ISOFLAVONE AGLYCONES ATTENUATE CIGARETTE SMOKE-INDUCED EMPHYSEMA VIA SUPPRESSION OF NEUTROPHILIC INFLAMMATION IN A COPD MURINE MODEL2019
- Author(s)
  Kazuya Kojima, Kazuhisa Asai, Hiroaki Kubo, Arata Sugitani, Yohkoh Kyomoto, Atsuko Okamoto, Kazuhiro Yamada, Naoki Ijiri, Tetsuya Watanabe, Kazuto Hirata, Tomoya Kawaguchi
- Organizer
  The 24 th Congress of the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08660
[Presentation] Irisin secreted from muscle by exercise ameliorates emphysema of cigarette smoke-induced COPD in mice2019
- Author(s)
  Hiroaki Kubo, Kazuhisa Asai, Atsushi Miyamoto, Hideaki Kadotani, Naomi Maruyama, Kazuya Kojima, Arata Sugitani, Yohkoh Kyomoto, Atsuko Okamoto, Kazuhiro Yamada, Tetsuya Watanabe, Tomoya Kawaguchi, Kazuto Hirata
- Organizer
  European Respiratory Society international Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08660
[Presentation] Relationship between peripheral blood irisin levels and muscle mass, sarcopenia, and pulmonary function measurements in COPD subjects.2016
- Author(s)
  Shinya Yoshida, Kazuhisa Asai, Yukari Sugiyama, Yohkoh Kyomoto, Tamaki Kawamoto, Kanako Sato, Yuko Kureya, Atsuko Okamoto, Kazuhiro Yamada, Naoko Yoshii, Tetsuya Watanabe, Masato Uji, Hiroshi Kanazawa, Kazuto Hirata
- Organizer
  21st Congress of the Asian Pacific Society of Respirology
- Place of Presentation
  バンコク（タイ）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09185
[Presentation] Expression Levels of Developmenal Genes Distinguish Non Specific Interstitial Pneumonia from Idiopathic Pulmonary Fibrosis and Highlight Potential Diagnostic Markers2016
- Author(s)
  Kazuhisa Konishi , Yasuhiro Kondoh , Hiroyuki Taniguchi , Atsuko Okamoto , Kathleen O. Lindell , Kazuhisa Asai , Yingze Zhang , Kevin Gibson , Naftali Kaminski , Dong Soon Kim
- Organizer
  American Thoracic Society 2016 International Conference
- Place of Presentation
  サンフランシスコ（アメリカ合衆国）
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09185
[Presentation] Decreased Nuclear Factor Erythroid 2-Related Factor 2 Expression Enhances Apoptosis of Airway Epithelial Cells in Patients with Chronic Obstructive Pulmonary Disease2016
- Author(s)
  Kazuhiro Yamada , Kazuhisa Asai , Yuko Kubo , Yohkoh Kyomoto , Tamaki Kawamoto , Shinya Yoshida , Kanako Sato , Norio Yamamoto , Naoko Yoshii , Tetsuya Watanabe , Masato Uji , Kazuto Hirata
- Organizer
  American Thoracic Society 2016 International Conference
- Place of Presentation
  サンフランシスコ（アメリカ合衆国）
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09185
[Presentation] Relationships between sarcopenia and pulmonary function, exercise capacity, and prognosis in patients with COPD2016
- Author(s)
  yukari sugiyama, kazuhisa asai, shinya yoshida, yohkoh kyomoto, tamaki kawamoto, kanako sato, yuko kureya, atsuko okamoto, kazuhiro yamada, naoko yoshii, tetsuya watanabe, masato uji, kazuto hirata,
- Organizer
  ERS International Congress 2016
- Place of Presentation
  ロンドン（イギリス）
- Year and Date
  2016-09-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09185
[Presentation] Atrial Natriuretic Peptide Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice2016
- Author(s)
  Atsuko Okamoto , Kazuhisa Konishi , Takashi Nojiri , Hiroshi Hosoda , Takeshi Tokudome , Kazuhisa Asai , Kazuto Hirata , Kenji Kangawa
- Organizer
  American Thoracic Society 2016 International Conference
- Place of Presentation
  サンフランシスコ（アメリカ合衆国）
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09185
[Presentation] Global gene expression analyses highlight the role of cellular plasma remodeling as a molecular function of airway epithelium in response to interleukin-13 treatment.2015
- Author(s)
  Yuko Kureya, Kazuhisa Konishi, Kazuhiro Yamada, Tetsuya Watanabe, Masato Uji, Kazuhisa Asai, Hiroshi Kanazawa, and Kazuto Hirata
- Organizer
  European Respiratory Society International Congress 2015
- Place of Presentation
  アムステルダム（オランダ）
- Year and Date
  2015-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09185
[Presentation] A case of rapidly progressed primary pleural synovial sarcoma.2015
- Author(s)
  Kazuhisa Asai, Kanako Sato, Yuko Kubo, Atsuko Okamoto, Kazuhiro Yamada, Naoko Yoshii, Tetsuya Watanabe, Kazuhisa Konishi, Masato Uji, Kazuto Hirata
- Organizer
  Chest Annual Meeting 2015
- Place of Presentation
  モントリオール（カナダ）
- Year and Date
  2015-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09185
[Presentation] 当院 COPD患者における GOLD 2011の総合的評価方法のカテゴリー分類における検討2013
- Author(s)
  井尻尚樹,栩野吉弘,吉井直子,玉垣学也,今橋由美子,浅井一久,鴨井博,金澤博,平田一人
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790818
[Presentation] 当院にて施行されたCTガイド下肺生検 92例の検討2013
- Author(s)
  中井俊之,香川直美,杉山由香里,井尻尚樹,山本典雄,玉垣学也,吉井直子,梅川加奈子,今橋由美子,永田光里,松浦邦臣,光岡茂樹,栩野吉弘,浅井一久,木村達郎,鴨井博,吉村成央,金澤博,工藤新三,平田一人
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790818
[Presentation] COPD患者の気道上皮細胞におけるNrf2発現の検討2013
- Author(s)
  今橋由美子, 栩野吉弘, 浅井一久, 井尻尚樹, 吉井直子, 玉垣学也, 鴨井博, 金澤博, 平田一人
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-24790818
[Presentation] COPD患者における運動耐容能と Impulse Oscillation System(IOS)のパラメータとの相関についての検討2013
- Author(s)
  吉井直子,金澤博,井尻尚樹,武田倫子,玉垣学也,今橋由美子,一丸之寿,浅井一久,栩野吉弘,鴨井博,平田一人
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790818
[Presentation] COPD患者の気道上皮細胞におけるNrf2発現の検討2013
- Author(s)
  今橋由美子、栩野吉弘、浅井一久、吉井直子、井尻尚樹、玉垣学也、鴨井博、金澤博、平田一人
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24790818
[Presentation] 当院における肺非結核性抗酸菌症に対する現状ならびに今後の課題2013
- Author(s)
  松浦邦臣,光岡茂樹,浅井一久,栩野吉弘,木村達郎,吉村成央,鴨井博,金澤博,工藤新三,平田一人
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790818
[Presentation] COPD患者における運動耐容能とImpulse Oscillation System(IOS)のパラメータとの相関についての検討2013
- Author(s)
  吉井直子, 金澤博, 井尻尚樹, 武田倫子, 玉垣学也, 今橋由美子, 一丸之寿, 浅井一久, 栩野吉弘, 鴨井博, 平田一人
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-24790818
[Presentation] COPD患者の気道上皮細胞におけるNrf2発現の検討2013
- Author(s)
  今橋由美子,栩野吉弘,浅井一久,井尻尚樹,吉井直子,玉垣学也,鴨井博,金澤博,平田一人
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790818
[Presentation] 当院COPD患者におけるGOLD 2011の総合的評価方法のカテゴリー分類における検討2013
- Author(s)
  井尻尚樹, 栩野吉弘, 吉井直子, 玉垣学也, 今橋由美子, 浅井一久, 鴨井博, 金澤博, 平田一人
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-24790818
[Presentation] 終末糖化産物は気道上皮におけるVascular Endothelial Growth Factorの産生を増強する2010
- Author(s)
  浅井一久, 金澤博, 小林大起, 白土直子, 渡辺徹也, 藤本寛樹, 児玉豊城, 松村佐恵子, 姜成勲, 鴨井博, 平田一人
- Organizer
  第50回日本呼吸器学会学術講演会
- Place of Presentation
  京都
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21790779
[Presentation] 気管支喘息におけるHigh mobility group box1 (HMGB-1)の関与についての検討2010
- Author(s)
  渡辺徹也, 浅井一久, 小林大起, 白土直子, 藤本寛樹, 鴨井博, 金澤博, 平田一人
- Organizer
  第60回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2010-11-25
- Data Source
  KAKENHI-PROJECT-21790779
[Presentation] 終末糖化産物は気道上皮におけるVascular Endothlial Growth Factorの産生を増強する2010
- Author(s)
  浅井一久, 金澤博, 小林大起, 白土直子, 渡辺徹也, 藤本寛樹, 児玉豊城, 松村佐恵子, 姜成勲, 鴨井博, 平田一人
- Organizer
  第50回日本呼吸器学会学術講演会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21790779
[Presentation] Advanced glycation end products stimulate vascular endothelial growth factor production from human airway epithelial cells in vitro and in vivo.2010
- Author(s)
  Asai K, Kanazawa H, Watanabe T, Fujimoto H, Kyoh S, Hirata K.
- Organizer
  American Thoracic Society
- Place of Presentation
  ニューオリンズ
- Year and Date
  2010-05-16
- Data Source
  KAKENHI-PROJECT-21790779
[]
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1. 渡辺徹也 (40735122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KUBO Akihito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. KOU Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 日野純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 宮里幹也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ASAI KAZUHISA 浅井 一久

浅井 一久 アサイ カズヒサ

Asai Kazuhisa 浅井 一久

ASAI Kazuhisa 浅井 一久

Research Projects

Research Products

Co-Researchers

慢性閉塞性肺疾患における筋肉関連遺伝子多型を加味した新規治療戦略に関する検討

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Mechanism of emphysema formation by controlling the Keap1-Nrf2 system and its application to COPD treatment strategiesPrincipal Investigator

Principal Investigator

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PI3K-PTEN imbalance is a potential new therapeutic target in COPDPrincipal Investigator

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Regulation of transcription factor in airway epithelial cells for asthma treatmentPrincipal Investigator

Principal Investigator

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Adipocytokine as an exacerbation factor for asthma and its possible involvement in therapeutic target for asthmaPrincipal Investigator

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[Book] 呼吸器疾患-state of arts Ver.6(第4章)主要疾患病態・診断・治療アレルギー性肺疾患アレルギー性気管支肺アスペルギルス症医学のあゆみ別冊呼吸器疾患- state of arts Ver.62013

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[Book] 医学のあゆみ別冊呼吸器疾患-state of arts Ver.62013

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[Book] 最新医学別冊「新しい診断と治療のABC」呼吸器2 喘息(改訂第2版)2011

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[Book] 最新医学別冊「新しい診断と治療のABC」呼吸器2喘息(改訂第2版)(第4章管理・治療薬物療法・選択基準)2011

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[Journal Article] Safety profile and risk factors for bleeding in transbronchial cryobiopsy using a two-scope technique for peripheral pulmonary lesions2022

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[Journal Article] Tumor microenvironment disparity in multiple primary lung cancers: Impact of non-intrinsic factors, histological subtypes, and genetic aberrations2021

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[Journal Article] Phase II Study of the Modified Weekly Nab-paclitaxel Regimen in Previously Treated Patients With Advanced Non?Small Cell Lung Cancer2021

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[Journal Article] 【COPD患者における栄養管理のポイント】COPDにおけるサルコペニア・フレイル2020

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[Journal Article] Exercise Ameliorates Emphysema Of Cigarette Smoke-Induced COPD In Mice Through The Exercise-Irisin-Nrf2 Axis.2019

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[Journal Article] Astaxanthin Suppresses Cigarette Smoke-Induced Emphysema through Nrf2 Activation in Mice.2019

ASAI KAZUHISA 浅井一久

浅井一久アサイカズヒサ

Asai Kazuhisa 浅井一久

ASAI Kazuhisa 浅井一久