KAWAGUCHI Tomoya 川口知哉

… Alternative Names

Researcher Number	70254422
Affiliation (Current)	2019 : 大阪市立大学, 大学院医学研究科, 教授 2019 : 独立行政法人国立病院機構近畿中央呼吸器センター, その他部局等, その他
Affiliation (based on the past Project Information) *help	2017 : 大阪市立大学, 大学院医学研究科, 准教授 2014 : 大阪市立大学, 医学部, 教授
Review Section/Research Field	Except Principal Investigator Tumor biology / Clinical oncology
Keywords	Except Principal Investigator 肺癌 / 発がん / 非小細胞肺癌 / 癌性胸膜炎 / FDG-PET / サイトケラチン / 発癌 / 遺伝子変異 / 分子標的治療 / 肺がん / 薬力学 / 薬物動態 / 化学療法

Mutational analysis on carcinogenesis in multiple primary lung cancersPrincipal InvestigatorOngoing
- Principal Investigator
  
  川口知哉
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Osaka City University
Nobel pharmacodynamics evaluation of molecular targeting agents: PHarmacokinetic/PHarmacodynamic Assessment on Malignant Effusions (PHAME)
- Principal Investigator
  
  KUBO Akihito
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Aichi Medical University

All 2017 2015 2014 2013 2011 Other

All Journal Article Presentation

[Journal Article] Phase I/II study of docetaxel combined with resminostat, an oral hydroxamic acid HDAC inhibitor, for advanced non-small cell lung cancer in patients previously treated with platinum-based chemotherapy2017
- Author(s)
  Tambo Yuichi、Hosomi Yukio、Sakai Hiroshi、Nogami Naoyuki、Atagi Shinji、Sasaki Yasutsuna、Kato Terufumi、Takahashi Toshiaki、Seto Takashi、Maemondo Makoto、Nokihara Hiroshi、Koyama Ryo、Nakagawa Kazuhiko、Kawaguchi Tomoya、Okamura Yuta、Nakamura Osamu、Nishio Makoto、Tamura Tomohide
- Journal Title
  
  Invest New Drugs
  
  Volume : 35 Pages : 217-226
- DOI
  10.1007/s10637-017-0435-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07176
[Journal Article] PIK3CA mutation as a distinctive genetic feature of non-small cell lung cancer with chronic obstructive pulmonary disease: a comprehensive mutational analysis from a multi-institutional cohort.2017
- Author(s)
  Sawa Kenji、Koh Yasuhiro、Kawaguchi Tomoya、Kambayashi Satoshi、Asai Kazuhisa、Mitsuoka Shigeki、Kimura Tatsuo、Yoshimura Naruo、Yoshimoto Naoki、Kubo Akihito、Saka Hideo、Matsumura Akihide、Wanibuchi Hideki、Yamamoto Nobuyuki、Nishiyama Noritoshi、Hirata Kazuto
- Journal Title
  
  Lung Cancer
  
  Volume : 112 Pages : 96-101
- DOI
  10.1016/j.lungcan.2017.07.039
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07128, KAKENHI-PROJECT-17K07176, KAKENHI-PROJECT-17K09162, KAKENHI-PROJECT-15K06878, KAKENHI-PROJECT-15K09185, KAKENHI-PROJECT-15K09226
[Journal Article] Association Between Environmental Tobacco Smoke Exposure and the Occurrence of EGFR Mutations and ALK Rearrangements in Never-smokers With Non?Small-cell Lung Cancer: Analyses From a Prospective Multinational ETS Registry2017
- Author(s)
  Kubo A, Soo RA, Ando M, Kawaguchi T, Ahn MJ, Ou S-HI
- Journal Title
  
  Clinical Lung Cancer
  
  Volume : 18 Pages : 535-42
- DOI
  10.1016/j.cllc.2017.01.005
- Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07128, KAKENHI-PROJECT-17K07176
[Journal Article] Multiplex Ultrasensitive Genotyping of Patients with Non-Small Cell Lung Cancer for Epidermal Growth Factor Receptor (EGFR) Mutations by Means of Picodroplet Digital PCR2017
- Author(s)
  Watanabe Masaru、Kawaguchi Tomoya、Isa Shun-ichi、Ando Masahiko、Tamiya Akihiro、Kubo Akihito、Saka Hideo、Takeo Sadanori、Adachi Hirofumi、Tagawa Tsutomu、Kawashima Osamu、Yamashita Motohiro、Kataoka Kazuhiko、Ichinose Yukito、Takeuchi Yukiyasu、Watanabe Katsuya、Matsumura Akihide、Koh Yasuhiro
- Journal Title
  
  EBio Medicine
  
  Volume : 21 Pages : 86-93
- DOI
  10.1016/j.ebiom.2017.06.003
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07128, KAKENHI-PROJECT-17K07176, KAKENHI-PROJECT-15K06878
[Journal Article] Reply to G Spitzer, et al; F Zhou,et al; and B Biswas.2015
- Author(s)
  Kawaguchi T, Ando M, Kubo A.
- Journal Title
  
  J Clin Oncol
  
  Volume : 33 Pages : 526-7
- DOI
  10.1200/jco.2014.58.5315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] The Role of Smoking Status on the Progression-Free Survival of Non-Small Cell Lung Cancer Patients Harboring Activating Epidermal Growth Factor Receptor (EGFR) Mutations Receiving First-Line EGFR Tyrosine Kinase Inhibitor Versus Platinum Doublet Chemotherapy: A Meta-Analysis of Prospective Randomized Trials.2015
- Author(s)
  Hasegawa Y, Ando M, Maemondo M, Yamamoto S, Isa S, Saka H, Kubo A, Kawaguchi T, Takada M, Rosell R, Kurata T, Ou SH.
- Journal Title
  
  Oncologist
  
  Volume : 20 Pages : 1-9
- DOI
  10.1634/theoncologist.2014-0285
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-15K09237, KAKENHI-PROJECT-25460896
[Journal Article] 1.Ultra-sensitive detection of the pretreatment EGFR T790M mutation in non-small-cell lung cancer patients with an EGFR-activating mutation using droplet digital PCR2015
- Author(s)
  Watanabe M, Kawaguchi T, Isa S-I, Ando M, Tamiya A, Kubo A, Saka H, Takeo S, Adachi H, Tagawa T, Kakegawa S, Yamashita M, Kataoka K, Ichinose Y, Takeuchi Y, Sakamoto K, Matsumura A, Koh Y.
- Journal Title
  
  Clin Cancer Res
  
  Volume : in press Pages : 3552-3560
- DOI
  10.1158/1078-0432.ccr-14-2151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-25460896
[Journal Article] Long-term Complete Response in a Patient with Disseminated Pulmonary Pleomorphic Carcinoma Induced by Cisplatin and Gemcitabine2014
- Author(s)
  Tamiya A, Asami K, Shimizu S, Matusmura A, Isa S-I, Okishio K, Kitaichi M, Atagi S, Takada M, Kawaguchi T, Kubo A.
- Journal Title
  
  Internal Medicine
  
  Volume : 53 Issue : 22 Pages : 2625-2628
- DOI
  10.2169/internalmedicine.53.2637
- Language
  English
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Randomized phase III trial of erlotinib versus docetaxel as second- or third-line therapy in patients with advanced non-small cell lung cancer: Docetaxel and Erlotinib Lung cancer TriAl (DELTA)2014
- Author(s)
  Kawaguchi T, Ando M, Asami K, Okano Y, Fukuda M, Nakagawa H, Ibata H, Kozuki T, Endo T, Tamura A, Kamimura M, Sakamoto K, Yoshimi M, Soejima Y, Tomizawa Y, Isa S, Takada M, Saka H, Kubo A.
- Journal Title
  
  J Clin Oncol
  
  Volume : 32 Pages : 1902-8
- DOI
  10.1200/jco.2013.52.4694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-25460896
[Journal Article] Long-term complete response in a patient with disseminated pulmonary pleomorphic carcinoma induced by cisplatin and gemcitabine.2014
- Author(s)
  Tamiya A, Asami K, Shimizu S, Matusmura A, Isa S-I, Okishio K, Kitaichi M, Atagi S, Takada M, Kawaguchi T, Kubo A
- Journal Title
  
  Internal Medicine (in press)
  
  Volume : na
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Role of Consolidation Chemotherapy after Concurrent Chemo-Radiotherapy in Locally Advanced Non-Small-Cell Lung Cancer2014
- Author(s)
  Tsujino K, Kurata T, Kawaguchi T, Kubo A, Takada M, Ando M.
- Journal Title
  
  J Thorac Oncol
  
  Volume : 9
- DOI
  10.1097/jto.0000000000000035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-25460896
[Journal Article] Human papilloma virus in non-small cell lung cancer in never smokers: A systematic review of the literature2014
- Author(s)
  Hasegawa Y, Ando M, Kubo A, Isa SI, Yamamoto S, Tsujino K, Kurata T, Ou SH, Takada M, Kawaguchi T
- Journal Title
  
  Lung Cancer
  
  Volume : 8 Pages : 8-13
- DOI
  10.1016/j.lungcan.2013.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-25460896
[Journal Article] Randomized phase III trial of erlotinib versus docetaxel as second- or third-line therapy in patients with advanced non-small cell lung cancer: Docetaxel and Erlotinib Lung cancer TriAl (DELTA).2014
- Author(s)
  Kawaguchi T, Ando M, Asami K, Okano Y, Fukuda M, Nakagawa H, Ibata H, Kozuki T, Endo T, Tamura A, Kamimura M, Sakamoto K, Yoshimi M, Soejima Y, Tomizawa Y, Isa S, Takada M, Saka H, Kubo A
- Journal Title
  
  J Clin Oncol (in press)
  
  Volume : na
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] A. Rationale and design of Japan Molecular Epidemiology for lung cancer (JME) study2013
- Author(s)
  Kawaguchi T, Ando M, Ito N, Isa SI, Tamiya A, Shimizu S, Saka H, Kubo A, Koh Y, Matsumura A
- Journal Title
  
  Clinical Lung Cancer
  
  Volume : 14 Pages : 596-600
- DOI
  10.1016/j.cllc.2013.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-24501363, KAKENHI-PROJECT-25460896
[Journal Article] Rationale and design of JME study: Japan Molecular Epidemiology for lung cancer study.2013
- Author(s)
  Kawaguchi T
- Journal Title
  
  Clin Lung Cancer (in press)
  
  Volume : 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314
[Journal Article] Is consolidation chemotherapy after concurrent chemo-radiotherapy beneficial for patients with locally advanced non-small cell lung cancer? A pooled analysis of the literature2013
- Author(s)
  Tsujino K, Kurata T, Yamamoto S, Kawaguchi T, Kubo A, Isa S, Hasegawa Y, Ou SH, Takada M, Ando M
- Journal Title
  
  J Thorac Oncol
  
  Volume : 8 Pages : 1181-9
- DOI
  10.1097/jto.0b013e3182988348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501314, KAKENHI-PROJECT-25460896
[Presentation] molecular epidemiology2017
- Author(s)
  Kawaguchi t
- Organizer
  世界肺癌学会総会
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-17K07176
[Presentation] Impacts of environmental tobacco smoke on EGFR mutations and ALK rearrangements in never smokers with non-small cell lung cancer: Analyses on a prospective multinational ETS registry.2013
- Author(s)
  Kubo A, Ando M, Soo RA, Kawaguchi T, Ou S-HI, Ahn M-J.
- Organizer
  15th World Conference on Lung Cancer
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] Impact of environmental tobacco smoke (ETS) on ALK rearrangements in never smokers (NS) with non-small cell lung cancer (NSCLC): Analyses on a prospective multinational ETS registry.2013
- Author(s)
  Kubo A, Ando M, Soo RA, Kawaguchi T, Ou S-HI, Ahn M-J.
- Organizer
  Annual Meeting of the American Society of Clinical Oncology
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] Randomized phase III trial of erlotinib (E) versus (v) docetaxel (D) as second or third line therapy in patients with advanced non-small cell lung cancer (NSCLC) who have wild type or mutant epidermal growth factor receptor (EGFR): Docetaxel and Erlotinib Lung cancer TriAl (DELTA).2013
- Author(s)
  Okano Y, Ando M, Asami K, Fukuda M, Nakagawa H, Ibata H, Kozuki T, Endo T, Tamura A, Kamimura M, Sakamoto K, Yoshimi M, Soejima Y, Tomizawa Y, Isa S, Takada M, Saka H, Kubo A, Kawaguchi T.
- Organizer
  Annual Meeting of the American Society of Clinical Oncology
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] 非小細胞肺癌(NSCLC)の癌性胸膜炎(MPE)におけるゲフィチニブの薬力学・薬物動態・臨床第II相試験2011
- Author(s)
  久保昭仁、洪　泰浩、堀　隆、伊佐俊一、福岡順也、川口知哉、安藤昌彦、岡本　勇、北市正則、安宅信二、河原正明、楠　洋子、山口悦郎、中川和彦、高田　實
- Organizer
  第51回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] Updated overall survival (OS) results of randomized phase III trial of erlotinib (E) versus (v) docetaxel (D) as second or third line therapy in patients with advanced non-small cell lung cancer (NSCLC): Docetaxel and Erlotinib Lung cancer TriAl (DELTA).
- Author(s)
  Ibata H, Ando M, Asami K, Okano Y, Fukuda M, Nakagawa H, Kozuki T, Endo T, Tamura A, Kamimura M, Sakamoto K, Yoshimi M, Soejima Y, Tomizawa Y, Isa S, Takada M, Saka H, Kubo A, Kawaguchi T.
- Organizer
  Annual Meeting of the American Society of Clinical Oncology
- Place of Presentation
  Chicago, IL, USA.
- Year and Date
  2014-05-30 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-23501314
[Presentation] The role of smoking status on the progression-free survival of non-small-cell lung cancer patients harboring activating epidermal growth factor (EGFR) mutations receiving first-line EGFR tyrosine kinase inhibitor: a meta-analysis of prospective randomized trials.
- Author(s)
  Hasegawa Y, Ando M, Maemondo M, Yamamoto S, Isa S, Saka H, Kubo A, Kawaguchi T, Takada M, Kurata T, Ou SH.
- Organizer
  Annual Meeting of the American Society of Clinical Oncology
- Place of Presentation
  Chicago, IL, USA.
- Year and Date
  2014-05-30 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-23501314

1. KOU Yasuhiro (80426519)

# of Collaborated Projects : 2results

# of Collaborated Products : 3results
2. KUBO Akihito (60416245)

# of Collaborated Projects : 1results

# of Collaborated Products : 20results
3. FUKUOKA Junya (00324575)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
4. TAKADA Minoru (20373516)

# of Collaborated Projects : 1results

# of Collaborated Products : 12results
5. ISA Shun-Ichi (60421913)

# of Collaborated Projects : 1results

# of Collaborated Products : 13results
6. 鰐渕英機

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
7. 浅井一久

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
8. 安藤昌彦

# of Collaborated Projects : 0results

# of Collaborated Products : 7results
9. 前門戸任

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
10. 長谷哲成

# of Collaborated Projects : 0results

# of Collaborated Products : 3results

KAWAGUCHI Tomoya 川口 知哉

川口 知哉 カワグチ トモヤ

Research Projects

Research Products

Co-Researchers

Mutational analysis on carcinogenesis in multiple primary lung cancersPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Nobel pharmacodynamics evaluation of molecular targeting agents: PHarmacokinetic/PHarmacodynamic Assessment on Malignant Effusions (PHAME)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Phase I/II study of docetaxel combined with resminostat, an oral hydroxamic acid HDAC inhibitor, for advanced non-small cell lung cancer in patients previously treated with platinum-based chemotherapy2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PIK3CA mutation as a distinctive genetic feature of non-small cell lung cancer with chronic obstructive pulmonary disease: a comprehensive mutational analysis from a multi-institutional cohort.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association Between Environmental Tobacco Smoke Exposure and the Occurrence of EGFR Mutations and ALK Rearrangements in Never-smokers With Non?Small-cell Lung Cancer: Analyses From a Prospective Multinational ETS Registry2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multiplex Ultrasensitive Genotyping of Patients with Non-Small Cell Lung Cancer for Epidermal Growth Factor Receptor (EGFR) Mutations by Means of Picodroplet Digital PCR2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reply to G Spitzer, et al; F Zhou,et al; and B Biswas.2015

Author(s)

Journal Title

DOI

Data Source

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 1.Ultra-sensitive detection of the pretreatment EGFR T790M mutation in non-small-cell lung cancer patients with an EGFR-activating mutation using droplet digital PCR2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-term Complete Response in a Patient with Disseminated Pulmonary Pleomorphic Carcinoma Induced by Cisplatin and Gemcitabine2014

Author(s)

Journal Title

DOI

Language

Data Source

[Journal Article] Randomized phase III trial of erlotinib versus docetaxel as second- or third-line therapy in patients with advanced non-small cell lung cancer: Docetaxel and Erlotinib Lung cancer TriAl (DELTA)2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-term complete response in a patient with disseminated pulmonary pleomorphic carcinoma induced by cisplatin and gemcitabine.2014

Author(s)

Journal Title

Data Source

[Journal Article] Role of Consolidation Chemotherapy after Concurrent Chemo-Radiotherapy in Locally Advanced Non-Small-Cell Lung Cancer2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human papilloma virus in non-small cell lung cancer in never smokers: A systematic review of the literature2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Randomized phase III trial of erlotinib versus docetaxel as second- or third-line therapy in patients with advanced non-small cell lung cancer: Docetaxel and Erlotinib Lung cancer TriAl (DELTA).2014

Author(s)

Journal Title

Data Source

KAWAGUCHI Tomoya 川口知哉

川口知哉カワグチトモヤ