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Hirata Yutaka  平田 豊

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HIRATA Yutaka  平田 豊

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Researcher Number 10441247
Other IDs
Affiliation (Current) 2025: 兵庫医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2025: 兵庫医科大学, 医学部, 講師
2016 – 2023: 兵庫医科大学, 医学部, 講師
2012 – 2013: 兵庫医科大学, 医学部, 講師
2007 – 2011: Hyogo College of Medicine, 医学部, 助教
Review Section/Research Field
Principal Investigator
Environmental physiology (including Physical medicine and Nutritional physiology) / Basic Section 52040:Radiological sciences-related / Basic Section 53030:Respiratory medicine-related
Except Principal Investigator
Basic Section 52040:Radiological sciences-related / Radiation science / Fusional basic brain science / Respiratory organ internal medicine
Keywords
Principal Investigator
カルシウム応答 / 延髄 / 中枢化学受容器 / 二酸化炭素 / microRNA / exosome / グリア細胞 / TRP / 培養細胞 / 水素イオン濃度 … More / ラジオ波焼灼術 / 肺転移 / 大腸ガン / 無再発 / DDS / lipiodol / 肝動脈塞栓術 / ガン / 気道上皮細胞 / miRNA / PAR-2 / YKL-40 / IL-33 / 喘息 / ATP / 呼吸調節 / 中枢性呼吸調節 / 環境生理 … More
Except Principal Investigator
肝細胞癌 / 肝動脈塞栓術 / 肝癌 / PD-L1 / siRNA / 動脈塞栓術 / HIF-1 / 低酸素誘導因子 / scRNA-seq / 複合免疫治療 / Abscopal効果 / アテゾリズマブ / 免疫逃避機構 / ラジオ波凝固治療 / TACE治療反応性 / バイオマーカー / トランスポゾン / ドライバー遺伝子 / ラット / ナノ粒子 / W/Oエマルジョン / リピオドール / マクロファージ極性制御 / ガン微小環境 / TGF-β1 / 腫瘍免疫微小環境 / TKI / 腫瘍免疫 / TAE / 腫瘍関連マクロファージ / 塞栓物質 / マイクロ粒子 / サイトカイン / RFA / 急性増悪 / 間質性肺炎 / ラジオ波凝固療法 / 肺 / インターベンショナルラジオジー / 放射線 / ラット肝細胞癌モデル / CCL28 / CCL17 / 免疫寛容 / 低酸素応答 / 免疫チェックポイント / 呼吸リズム生成機構 / カルシウムイメージング / ニューロングリア相互作用 / 加齢 / 気道過分泌 / ステロイド低感受性 / キチナーゼ関連蛋白質 / アレルギー・喘息 / 慢性炎症性気道疾患 / 気道リモデリング / YKL-40 / 喘息 / キチナーゼ関連タンパク質 / 難治性気道疾患 Less
  • Research Projects

    (15 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (19 People)
  •  Role of tumor suppressor miRNAs contained in exosomes in the blood of RFA cancer patientsPrincipal Investigator

    • Principal Investigator
      平田 豊
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Hyogo Medical University
  •  ドライバー遺伝子に基づくTACE治療反応性の血清バイオマーカーの開発

    • Principal Investigator
      上嶋 英介
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Kobe University
  •  ラジオ波凝固治療を軸にしたガン複合免疫療法の開発

    • Principal Investigator
      高木 治行
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Hyogo Medical University
  •  Development of hepatic artery embolization using cancer-accumulating contrast medium for delivery of microRNA therapeutics aiming at recurrence-freePrincipal Investigator

    • Principal Investigator
      平田 豊
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Hyogo Medical University
  •  Development of small interfering RNA system with nanoparticle type oily contrast media and application to transcatheter arterial embolization

    • Principal Investigator
      Taniguchi Junichi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Hyogo Medical University
  •  Elucidation of hypoxia-responsive genes that control recurrence after hepatic artery embolization and development of siRNA-loaded embolization preparations

    • Principal Investigator
      Takaki Haruyuki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Hyogo Medical University
  •  Novel therapeutic strategies based on macrophage polarization in the tumor microenvironment after hepatic arterial embolization.

    • Principal Investigator
      Ueshima Eisuke
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Kobe University
  •  Factors related with acute exacerbation of interstitial pneumonia after lung radiofrequency ablation

    • Principal Investigator
      Kodama Hiroshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Hyogo Medical University
  •  Elucidation of IL-33 expression mechanism by PAR-2 control aiming at application of asthma treatmentPrincipal Investigator

    • Principal Investigator
      Hirata Yutaka
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Hyogo Medical University
  •  Hepatic artery embolization and hypoxia: roles in the tumor recurrence and application for new treatment strategy

    • Principal Investigator
      TAKAKI Haruyuki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Hyogo Medical University
  •  The elucidation of central chemosensitive respiratory regulation by TRP channels expressed in glial cell.Principal Investigator

    • Principal Investigator
      HIRATA Yutaka
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Hyogo Medical University
  •  Astrocytes drive respiratory rhythm testing a new paradigm

    • Principal Investigator
      OKU Yoshitaka
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Fusional basic brain science
    • Research Institution
      Hyogo Medical University
  •  Role of chitinase like protein in chronic inflammatory airway diseases

    • Principal Investigator
      MATSUMOTO Hisako
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kyoto University
  •  The elucidation of molecular basis on mechanisms for chemosensitive respiratory regulationPrincipal Investigator

    • Principal Investigator
      HIRATA Yutaka
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Hyogo College of Medicine
  •  The elucidation of mechanisms for central chemoreceptorPrincipal Investigator

    • Principal Investigator
      HIRATA Yutaka
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      Hyogo College of Medicine

All 2024 2023 2022 2020 2018 2012 2011 2010 2008

All Journal Article Presentation

  • [Journal Article] Liver regeneration after portal vein embolization: comparison between absolute ethanol and N-butyl-cyanoacrylate in an in vivo rat model2023

    • Author(s)
      Mitsunari Maruyama, Haruyuki Takaki, Naoko Yamada, Yutaka Hirata, Koichiro Yamakado, Hajime Kitagaki
    • Journal Title

      Diagn Interv Radiol

      Volume: Online ahead of print Issue: 4 Pages: 621-627

    • DOI

      10.4274/dir.2022.211144

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17199, KAKENHI-PROJECT-20K08010
  • [Journal Article] Hepatic Artery Embolization Enhances Expression of Programmed Cell Death 1 Ligand 1 in an Orthotopic Rat Hepatocellular Carcinoma Model: In?Vivo and in?Vitro Experimentation2020

    • Author(s)
      Takaki Haruyuki、Hirata Yutaka、Ueshima Eisuke、Kodama Hiroshi、Matsumoto Seiji、Wada Reona、Suzuki Hitomi、Nakasho Keiji、Yamakado Koichiro
    • Journal Title

      Journal of Vascular and Interventional Radiology

      Volume: 31 Issue: 9 Pages: 1475-1482.e2

    • DOI

      10.1016/j.jvir.2020.03.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08010
  • [Journal Article] Interleukin-13 enhanced Ca2+ oscillations in airway smooth muscle cells2012

    • Author(s)
      Matsumoto, Hirata, et al.
    • Journal Title

      Cytokine

      Volume: 57 Pages: 19-24

    • NAID

      120003726117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590839
  • [Journal Article] Interleukin-13 enhanced Ca2+oscillations in airway smooth muscle cells2012

    • Author(s)
      Matsumoto H, Hirata Y, Oku Y. et al
    • Journal Title

      Cytokine

      Volume: 57 Pages: 19-24

    • NAID

      120003726117

    • Data Source
      KAKENHI-PROJECT-22590839
  • [Journal Article] TRP channels are involved in mediating hypercapnic Ca^<2+> responses in rat glia-rich medullary cultures independently of extracellular pH.2010

    • Author(s)
      Hirata Y, Oku Y.
    • Journal Title

      Cell Calcium 48

      Pages: 124-142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790231
  • [Journal Article] Ca2+ overload and sarcoplasmic reticulum instability in tric-a null skeletal muscle.2010

    • Author(s)
      Zhao X, Yamazaki D, Park KH, Komazaki S, Tjondrokoesoemo A, Nishi M, Lin P, Hirata Y, Brotto M, Takeshima H, Ma J.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 26 Pages: 37370-37376

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790231
  • [Journal Article] TRP channels are involved in mediating hypercapnic Ca2+ responses in rat glia-rich medullary cultures independent of extracellular pH.2010

    • Author(s)
      Hirata Y, Oku Y.
    • Journal Title

      Cell Calcium

      Volume: 48 Pages: 124-132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790231
  • [Presentation] 肺RFA患者の血液中exosome由来のmicroRNAのガン増殖作用2024

    • Author(s)
      平田 豊、高木 治行、上嶋 英介、児玉 大志、谷口 純一、和田 玲緒名、山門 亨一郎
    • Organizer
      第2回 日本アブレーション研究会
    • Data Source
      KAKENHI-PROJECT-22K07734
  • [Presentation] 無再発生存のガン患者の血液中のexosome由来のmicroRNA2023

    • Author(s)
      平田 豊、高木 治行、児玉 大志、山門 亨一郎 越久 仁敬
    • Organizer
      第46回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K07734
  • [Presentation] Exosomal microRNAs in the blood of non-recurrent cancer patients2023

    • Author(s)
      Yutaka Hirata, Haruyuki Takaki, Hiroshi Kodama, Eisuke Ueshima, Koichiro Yamakado, Yoshitaka Oku
    • Organizer
      第97回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K07734
  • [Presentation] 肺RFA患者の血液中exosome由来のmicroRNA2023

    • Author(s)
      平田 豊、高木 治行、小林 薫、加古 泰一、小笠原 篤、児玉 大志、谷口 純一、河本 悠、高萩 基仁、吉村 奈穂美、山門 亨一郎
    • Organizer
      第1回総会 日本アブレーション研究会
    • Data Source
      KAKENHI-PROJECT-22K07734
  • [Presentation] Embolization Induced Tumor-Associated Macrophage Polarization in Tumor Immune Microenvironment can be Reprogrammed by Lenvatinib in a Rat Hepatoma Model2022

    • Author(s)
      Ueshima E, Sofue K, Takaki H, Hirata Y, Kodama H, Hamada M, Matsushiro K, Sasaki K, Gentsu T, Okada T, Yamaguchi M, Yamakado K, Sugimoto K, Murakami T
    • Organizer
      Society of Interventional Radiology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08133
  • [Presentation] リピオドールの細胞内取り込みについての検討2022

    • Author(s)
      高木治行、平田豊、上嶋英介、児玉大志、山門亨一郎
    • Organizer
      第71回関西IVR研究会
    • Data Source
      KAKENHI-PROJECT-20K08010
  • [Presentation] 21G電極針を用いたRFA:抗腫瘍効果の検討2022

    • Author(s)
      高木治行、平田豊、上嶋英介、児玉大志、山門亨一郎
    • Organizer
      第71回関西IVR研究会
    • Data Source
      KAKENHI-PROJECT-20K08010
  • [Presentation] Exosomal microRNAs in the blood of lung RFA patients2022

    • Author(s)
      Yutaka Hirata, Haruyuki Takaki, Kaoru Kobayashi, Yasukazu Kako, Atsushi Ogasawara, Hiroshi Kodama, Junichi Taniguchi, Yu Kawamoto, Motonori Takahagi, Taiki Morimura, Nahomi Yoshimura, Koichiro Yamakado
    • Organizer
      JSIR, ISIR & APSCVIR 2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07734
  • [Presentation] IL-33 expression is regulated by YKL-40 in airway epithelial cells.2018

    • Author(s)
      平田 豊、越久 仁敬、松本 久子
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08194
  • [Presentation] TRPチャネルが関与する延髄由来グリア細胞における高CO2負荷に対する細胞外pH非依存的なCa応答2012

    • Author(s)
      平田豊、越久仁敬
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      国立京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-23590292
  • [Presentation] TRPチャネルが関与する、ラット延髄由来グリア細胞における高CO2負荷に対する細胞外pH非依存的なCa応答2012

    • Author(s)
      平田豊, 越久仁敬
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2012-03-14
    • Data Source
      KAKENHI-PROJECT-23590292
  • [Presentation] TRP channels are involved in mediating hypercapnic Ca2+ responses in rat glia-rich medullary cultures independent of extracellular pH2011

    • Author(s)
      平田豊, 越久仁敬
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PROJECT-23590292
  • [Presentation] Glial TRP involved in hypercapnic Ca responses2011

    • Author(s)
      平田豊、越久仁敬
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-23590292
  • [Presentation] Primary-cultured medullary cells, possibly glial cells, respond to hypercapnia and/or hypocapnia independently of extracellular pH in rats2008

    • Author(s)
      Yutaka Hirata & Yoshitaka Oku
    • Organizer
      第6回ヨーロッパ神経科学会
    • Place of Presentation
      スイス、ジュネーブ
    • Year and Date
      2008-07-15
    • Data Source
      KAKENHI-PROJECT-19790182
  • [Presentation] Primary-cultured medullary cells, possibly glial cells, respond to hypercapnia and/or hypocapnia independently of extracellular pH in rats2008

    • Author(s)
      Yutaka Hirata & Yoshitaka Oku
    • Organizer
      第6回ヨーロッパ神経科学会Federation of European Neurosciences Societies(FENS)
    • Place of Presentation
      スイス、ジュネーブ
    • Year and Date
      2008-07-15
    • Data Source
      KAKENHI-PROJECT-19790182
  • 1.  TAKAKI Haruyuki (30378377)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 8 results
  • 2.  山門 亨一郎 (20263022)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 3 results
  • 3.  Kodama Hiroshi (20422834)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 4.  OKU Yoshitaka (20252512)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 5.  MATSUMOTO Hisako (60359809)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 6.  Ueshima Eisuke (40645561)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  祖父江 慶太郎 (90622027)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  ITO Yutaka (80362482)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KUBO Shuji (10441320)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OKADA Yasumasa (80160688)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  IKEGAYA Yuji (10302613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  Taniguchi Junichi (60818714)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  中正 恵二 (00217712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  廣田 省三 (20181216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  善本 知広 (60241171)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  鈴木 亮佑 (80611540)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  村上 卓道 (20252653)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 18.  小松 昇平 (30444590)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  丸山 光也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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