Ueta Ryo 植田亮

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UETA Ryo 植田亮

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Researcher Number	10445025
Other IDs
Affiliation (based on the past Project Information) *help	2022: 東京大学, 医科学研究所, 助教 2015 – 2020: 東京大学, 医科学研究所, 助教 2012 – 2013: 東京大学, 医科学研究所, 助教 2011: 大阪大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Functional biochemistry / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Medium-sized Section 48:Biomedical structure and function and related fields / General medical chemistry / Biological Sciences
Keywords	Principal Investigator シグナル伝達 / 神経筋シナプス / 神経生物学 / 神経科学 / 神経筋疾患 / 出芽酵母 / ミトコンドリア / 鉄 / ヘム Except Principal Investigator シグナル伝達 … More / 神経科学 / 神経筋シナプス / 神経筋シナプス形成シグナル / 神経筋疾患 / 運動機能障害 / 細胞内シグナル伝達 / 癌 / 蛋白質 / 炎症 / 免疫 / ユビキチン / 細胞・組織 / 免疫学 / 細胞・組織 / タンパク質 / 酵素 Less

Signaling in NMJ formation and therapeutic intervention against neuromuscular disorders
- Principal Investigator
  
  Yamanashi Yuji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  The University of Tokyo
Elucidation of molecules and signaling pathways regulating neuromuscular junction formationPrincipal Investigator
- Principal Investigator
  
  Ueta Ryo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  The University of Tokyo
Signaling in NMJ formation and its synaptopathy
- Principal Investigator
  
  Yamanashi Yuji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
Elucidation of the mechanism underlying the formation of neuromuscular synapsePrincipal Investigator
- Principal Investigator
  
  Ueta Ryo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
molecular mechanism underlying intracellular heme transportPrincipal Investigator
- Principal Investigator
  
  UETA Ryo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Studies on novel NF-kB activation mechanism through linear ubiquitination and its related disorders
- Principal Investigator
  
  TOKUNAGA Fuminori
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
  Osaka University

All 2021 2020 2017 2012

All Journal Article Presentation Patent

[Journal Article] Effect of salbutamol on neuromuscular junction function and structure in a mouse model of DOK7 congenital myasthenia2020
- Author(s)
  Webster RG, Vanhaesebrouck AE, Maxwell SE, Cossins JA, Liu W, Ueta R, Yamanashi Y, Beeson DMW
- Journal Title
  
  Hum. Mol. Genet.
  
  Volume: 29 Issue: 14 Pages: 2325-2336
- DOI
  10.1093/hmg/ddaa116
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00496
[Journal Article] DOK7 Gene Therapy Enhances Neuromuscular Junction Innervation and Motor Function in Aged Mice2020
- Author(s)
  Ueta R, Sugita S, Minegishi Y, Shimotoyodome A, Ota N, Ogiso N, Eguchi T, Yamanashi Y
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 8 Pages: 101385-101385
- DOI
  10.1016/j.isci.2020.101385
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01532, KAKENHI-PROJECT-20H00496, KAKENHI-PROJECT-18K06127
[Journal Article] The carboxyl-terminal region of Dok-7 plays a key, but not essential, role in activation of muscle-specific receptor kinase MuSK and neuromuscular synapse formation2017
- Author(s)
  Ryo Ueta, Tohru Tezuka, Yosuke Izawa, Sadanori Miyoshi, Satoru Nagatoishi, Kouhei Tsumoto, Yuji Yamanashi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 161 Pages: 269-277
- DOI
  10.1093/jb/mvw073
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14J08885, KAKENHI-PROJECT-16K14575, KAKENHI-PROJECT-15K18500
[Journal Article] Iron-induced dissociation of the Aft1p transcriptional regulator from target gene promoters is an initial event in iron-dependent gene suppression2012
- Author(s)
  Ueta R, Fujiwara N, Iwai K, Yamaguchi-Iwai Y
- Journal Title
  
  Mol Cell Biol
  
  Volume: 32 (24) Issue: 24 Pages: 4998-5008
- DOI
  10.1128/mcb.00726-12
- NAID
  120005173382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770121
[Patent] Methods and Compositions for Treatment of Age-Related Dysfunction2021
- Inventor(s)
  山梨　裕司、植田　亮、杉田　聡、峯岸　慶彦
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20H00496
[Patent] Methods and Compositions for Treatment of Age-Related Dysfunction2020
- Inventor(s)
  山梨　裕司、植田　亮、杉田　聡、峯岸　慶彦
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-20H00496
[Patent] Methods and Compositions for Treatment of Age-Related Dysfunction2020
- Inventor(s)
  山梨　裕司、植田　亮、杉田　聡、峯岸　慶彦
- Industrial Property Rights Holder
  国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-17H01532
[Presentation] 神経筋接合部（NMJ）の形成増強治療は老齢マウスにおけるNMJの神経結合を増強し、運動機能と筋力を強化する2020
- Author(s)
  江口貴大、杉田聡、峯岸慶彦、下豊留玲、太田宣康、小木曽昇、植田亮、山梨裕司
- Organizer
  第6回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00496
[Presentation] DOK7発現ベクターの投与は老齢マウスのNMJにおける神経結合を増強し、運動機能と筋力を強化する2020
- Author(s)
  江口貴大、杉田聡、峯岸慶彦、下豊留玲、太田宣康、小木曽昇、植田亮、山梨裕司
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H00496
[Presentation] 神経筋接合部の形成に必要な受容体型キナーゼMuSKのDok-7による活性化機構の解明2017
- Author(s)
  植田亮、手塚徹、井澤洋介、三好貞徳、長門石暁、津本浩平、山梨裕司
- Organizer
  日本筋学会第3回学術集会
- Data Source
  KAKENHI-PROJECT-15K18500

1. Yamanashi Yuji (40202387)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. TOKUNAGA Fuminori (00212069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. NAGATOISHI Satoru (30550248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 手塚徹 (50312319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 江口貴大 (60845056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 荒川正行 (90398868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ueta Ryo 植田 亮

UETA Ryo 植田 亮

Research Projects

Research Products

Co-Researchers

Signaling in NMJ formation and therapeutic intervention against neuromuscular disorders

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of molecules and signaling pathways regulating neuromuscular junction formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Signaling in NMJ formation and its synaptopathy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the mechanism underlying the formation of neuromuscular synapsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

molecular mechanism underlying intracellular heme transportPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on novel NF-kB activation mechanism through linear ubiquitination and its related disorders

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Effect of salbutamol on neuromuscular junction function and structure in a mouse model of DOK7 congenital myasthenia2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DOK7 Gene Therapy Enhances Neuromuscular Junction Innervation and Motor Function in Aged Mice2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The carboxyl-terminal region of Dok-7 plays a key, but not essential, role in activation of muscle-specific receptor kinase MuSK and neuromuscular synapse formation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Iron-induced dissociation of the Aft1p transcriptional regulator from target gene promoters is an initial event in iron-dependent gene suppression2012

Author(s)

Journal Title

DOI

NAID

Data Source

[Patent] Methods and Compositions for Treatment of Age-Related Dysfunction2021

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] Methods and Compositions for Treatment of Age-Related Dysfunction2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] Methods and Compositions for Treatment of Age-Related Dysfunction2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

Ueta Ryo 植田亮

UETA Ryo 植田亮