MORIGUCHI Takashi 森口尚

Researcher Number	10447253
Affiliation (based on the past Project Information) *help	2016 – 2023: 東北医科薬科大学, 医学部, 教授 2012 – 2015: 東北大学, 医学(系)研究科(研究院), 講師 2014: 東北大学, 大学院医学系研究科・医化学分野, 講師 2010 – 2011: 東北大学, 大学院・医学系研究科, 講師 2007 – 2008: Tohoku University, 大学院・医学系研究科, 講師
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Pathological medical chemistry / General medical chemistry / Developmental biology Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Experimental pathology
Keywords	Principal Investigator GATA2 / GATA転写因子 / 炎症性サイトカイン / トランスジェニックマウス / マスト細胞 / ヒスタミン / GATA因子 / 炎症性疾患 / 感染症 / 感染防御 … More / 敗血症 / 腎集合管 / マクロファージ / 腎集合管細胞 / 腎臓病 / メサンギウム細胞 / 転写因子複合体 / サイトカイン / 血管内皮細胞 / インターロイキン６ / siRNA / 好酸球 / 気管支喘息 / ヒスチジン脱炭酸酵素 / ChIPシーケンス / RNAシーケンス / IL6 / 免疫不全症 / 慢性炎症性疾患 / エピジェネティクス / アレルギー / インビボイメージング / リポポリ多糖 / 遺伝子発現制御 / 慢性腎臓病 / 慢性炎症 / ミトキサントロン / 急性腎臓病 / 腎虚血再還流障害 / 阻害剤 / GATA転写因子群 / 腎虚血再灌流障害 / アナフィラキシー / 細菌人工染色体 / リポ多糖 / 虚血再還流 / アクアポリン / 糸球体腎炎 / GATA3 / 尿細管 / 虚血再還流障害 / AE1 / 糖尿病性腎症 / Aqp2 / 腎尿細管細胞 / エストロゲン受容体融合型GATA-1 / レトロウイルスベクター / GATA-1BAC / エストロゲン受容体合型GATA-1 / ChIP on Chip解析 / GATA-1ノックダウンマウス / 白血病 / 赤血球 / BAC / GATA1 … More Except Principal Investigator GATA転写因子 / 転写因子GATA1 / ANCA関連血管炎 / 好酸球性多発血管炎性肉芽腫症 / 肺上皮細胞分化 / Nrf2－Keap1 / Nrf2-Keap1 / 肺再生 / 遺伝子 / ストレス / 環境 / 発現制御 / エリスロポエチン / 低酸素 / 酸化ストレス / Keap1 / Nrf2 / 環境応答 Less

Therapeutic strategy against infectious and inflammatory diseases by targeting master regulators of mast cells and eosinophilsPrincipal Investigator
- Principal Investigator
  
  森口尚
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
好酸球性多発血管炎性肉芽腫症におけるGATA転写因子の病態への関与
- Principal Investigator
  
  城田祐子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Selective ablation of mast cells and eosinophils by GATA factor inhibition for asthma therapyPrincipal Investigator
- Principal Investigator
  
  Moriguchi Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Epigenetic regulation of cytokiine gene expression underlying inflammatory diseasesPrincipal Investigator
- Principal Investigator
  
  森口尚
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Tohoku Medical and Pharmaceutical University
Proinflammatory role of renal collecting duct cells in kidney diseasePrincipal Investigator
- Principal Investigator
  
  MORIGUCHI Takashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku Medical and Pharmaceutical University
Lung regeneration from iPS by using Nrf2 activator
- Principal Investigator
  
  SATOH Hironori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  National Cancer Center Japan
  Tohoku University
GATA factor-mediated maintenance of renal functionPrincipal Investigator
- Principal Investigator
  
  MORIGUCHI Takashi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku Medical and Pharmaceutical University
  Tohoku University
腎尿細管におけるGATA転写因子を介した生体恒常性維持機構の解明Principal Investigator
- Principal Investigator
  
  森口尚
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Analysis of Gata1 gene transcriptional regulationPrincipal Investigator
- Principal Investigator
  
  MORIGUCHI Takashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Tohoku University
Molecular Mechanisms of Adaptive Responses to Food and Oxygen
- Principal Investigator
  
  YAMAMOTO Masayuki
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Tohoku University

[Book] Hematopoietic Stem Cell Biology2010
- Author(s)
  Moriguchi T, Suzuki M, Engel JD, Yamamoto M.
- Total Pages
  25
- Publisher
  Springer Science
- Data Source
  KAKENHI-PROJECT-22590260
[Book] Diabetes Frontier2010
- Author(s)
  宇留野晃、森口尚、山本雅之
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Exogenous l-fucose attenuates neuroinflammation induced by lipopolysaccharide2024
- Author(s)
  Xu Xing、Fukuda Tomohiko、Takai Jun、Morii Sayaka、Sun Yuhan、Liu Jianwei、Ohno Shiho、Isaji Tomoya、Yamaguchi Yoshiki、Nakano Miyako、Moriguchi Takashi、Gu Jianguo
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 1 Pages: 105513-105513
- DOI
  10.1016/j.jbc.2023.105513
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19443, KAKENHI-PROJECT-22K06615, KAKENHI-PROJECT-22K06913, KAKENHI-PROJECT-21K06547, KAKENHI-PROJECT-23K27133
[Journal Article] Mtc6/Ehg2 is a novel endoplasmic reticulum-resident glycoprotein essential for high-pressure tolerance2024
- Author(s)
  Uemura Satoshi、Mochizuki Takahiro、Kato Yusuke、Mioka Tetsuo、Watanabe Riseko、Fuchita Mai、Yamada Mao、Noda Yoichi、Moriguchi Takashi、Abe Fumiyoshi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 2 Pages: 1-12
- DOI
  10.1093/jb/mvae035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06913, KAKENHI-PROJECT-23K23514
[Journal Article] Perturbed collagen metabolism underlies lymphatic recanalization failure in <i>Gata2</i> heterozygous deficient mice2024
- Author(s)
  Watanabe-Asaka Tomomi、Hayashi Moyuru、Harada Takuya、Uemura Satoshi、Takai Jun、Nakamura Yasuhiro、Moriguchi Takashi、Kawai Yoshiko
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 5 Pages: 1-10
- DOI
  10.1093/jb/mvad122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06913, KAKENHI-PROJECT-23K07165
[Journal Article] Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels2022
- Author(s)
  Satoh Hironori、Arai Yasuhito、Furukawa Eisaku、Moriguchi Takashi、Hama Natuko、Urushidate Tomoko、Totoki Yasushi、Kato Mamoru、Ohe Yuichiro、Yamamoto Masayuki、Shibata Tatsuhiro
- Journal Title
  
  Carcinogenesis
  
  Volume: - Issue: 7 Pages: 613-623
- DOI
  10.1093/carcin/bgac041
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07388, KAKENHI-PROJECT-22K06913
[Journal Article] The Il6 -39 kb enhancer containing clustered GATA2- and PU.1-binding sites is essential for Il6 expression in murine mast cells2022
- Author(s)
  Ohmori Shin’ya、Takai Jun、Uemura Satoshi、Otsuki Akihito、Mori Tetsuya、Ohneda Kinuko、Moriguchi Takashi
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 9 Pages: 104942-104942
- DOI
  10.1016/j.isci.2022.104942
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06816, KAKENHI-PROJECT-22K06913, KAKENHI-PROJECT-22K15376
[Journal Article] Pleiotropic roles of N-glycans for enzyme activities and stabilities of MIPC synthases, Csh1 and Sur1/Csg1, in Saccharomyces cerevisiae2022
- Author(s)
  Uemura Satoshi、Moriguchi Takashi
- Journal Title
  
  Glycobiology
  
  Volume: 32 Pages: 778-790
- DOI
  10.1093/glycob/cwac035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05561, KAKENHI-PROJECT-22K06913
[Journal Article] An erythroid-to-myeloid cell fate conversion is elicited by LSD1 inactivation2021
- Author(s)
  Yu Lei、Myers Greggory、Ku Chia-Jui、Schneider Emily、Wang Yu、Singh Sharon A.、Jearawiriyapaisarn Natee、White Andrew、Moriguchi Takashi、Khoriaty Rami、Yamamoto Masayuki、Rosenfeld Michael G.、Pedron Julien、Bushweller John H.、Lim Kim-Chew、Engel James Douglas
- Journal Title
  
  Blood
  
  Volume: 138 Issue: 18 Pages: 1691-1704
- DOI
  10.1182/blood.2021011682
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07388
[Journal Article] 転写因子GATA2 の遺伝子変異に伴う免疫不全症．2021
- Author(s)
  高井淳、城田祐子、森口尚．
- Journal Title
  
  血液内科．
  
  Volume: 82． Pages: 642-642
- Data Source
  KAKENHI-PROJECT-21K08444
[Journal Article] Gata2 heterozygous mutant mice exhibit reduced inflammatory responses and impaired bacterial clearance2021
- Author(s)
  Takai Jun、Shimada Takashi、Nakamura Tadaho、Engel James Douglas、Moriguchi Takashi
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 8 Pages: 102836-102836
- DOI
  10.1016/j.isci.2021.102836
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07388
[Journal Article] GATA2 participates in the recanalization of lymphatic vessels after surgical lymph node extirpation2021
- Author(s)
  Watanabe‐Asaka Tomomi、Hayashi Moyuru、Uemura Satoshi、Takai Jun、Suzuki Akane、Moriguchi Takashi、Kawai Yoshiko
- Journal Title
  
  Genes to Cells
  
  Volume: 26 Issue: 7 Pages: 474-484
- DOI
  10.1111/gtc.12852
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07388
[Journal Article] Development and Carcinogenesis: Roles of GATA Factors in the Sympathoadrenal and Urogenital Systems2021
- Author(s)
  Moriguchi Takashi
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 3 Pages: 299-299
- DOI
  10.3390/biomedicines9030299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07388
[Journal Article] 原発性免疫不全症とヒトGATA2遺伝子変異2020
- Author(s)
  高井淳、森口尚
- Journal Title
  
  Bio Clinica
  
  Volume: 35 Pages: 69-72
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Journal Article] 敗血症性肺障害時の肺に集積するヒスタミン産生能を持つ好中球の役割2020
- Author(s)
  森口　尚、高井　淳
- Journal Title
  
  生化学
  
  Volume: 92 Pages: 268-271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07388
[Journal Article] Histamine and histidine decarboxylase: Immunomodulatory functions and regulatory mechanisms2020
- Author(s)
  Moriguchi Takashi、Takai Jun
- Journal Title
  
  Genes to Cells
  
  Volume: - Issue: 7 Pages: 443-449
- DOI
  10.1111/gtc.12774
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05041, KAKENHI-PROJECT-19K07388, KAKENHI-PROJECT-18K15068
[Journal Article] 原発性免疫不全症とヒトGATA2遺伝子変異2020
- Author(s)
  高井　淳、森口　尚
- Journal Title
  
  Bio Clinica
  
  Volume: 35 Pages: 69-72
- Data Source
  KAKENHI-PROJECT-19K07388
[Journal Article] 敗血症性肺障害時の肺に集積するヒスタミン産生能を持つ好中球の役割2020
- Author(s)
  森口尚、高井淳
- Journal Title
  
  生化学
  
  Volume: 92 Pages: 268-271
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Journal Article] GATA2 functions in adrenal chromaffin cells2020
- Author(s)
  Watanabe‐Asaka Tomomi、Hayashi Moyuru、Engel James Douglas、Kawai Yoshiko、Moriguchi Takashi
- Journal Title
  
  Genes to Cells
  
  Volume: 9 Issue: 9 Pages: 607-614
- DOI
  10.1111/gtc.12795
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07388, KAKENHI-PROJECT-18K07241
[Journal Article] Lipopolysaccharide-induced Expansion of Histidine Decarboxylase-Expressing Ly6G + Myeloid Cells Identified by Exploiting Histidine Decarboxylase BAC-GFP Transgenic Mice2019
- Author(s)
  Takai J, Ohtsu H, Sato A, Uemura S, Fujimura T, Yamamoto M, Moriguchi T.
- Journal Title
  
  Sci Rep.
  
  Volume: 9(1) Issue: 1 Pages: 15603-15603
- DOI
  10.1038/s41598-019-51716-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00874, KAKENHI-PROJECT-19K07388, KAKENHI-PROJECT-18K15068, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05041
[Journal Article] Spiral ganglion cell degeneration‐induced deafness as a consequence of reduced GATA factor activity2019
- Author(s)
  Hoshino Tomofumi、Terunuma Tsumoru、Takai Jun、Uemura Satoshi、Nakamura Yasuhiro、Hamada Michito、Takahashi Satoru、Yamamoto Masayuki、Engel James Douglas、Moriguchi Takashi
- Journal Title
  
  Genes to Cells
  
  Volume: 24 Issue: 8 Pages: 534-545
- DOI
  10.1111/gtc.12705
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07388, KAKENHI-PUBLICLY-18H05041
[Journal Article] 転写因子GATA2と免疫不全症2019
- Author(s)
  高井　淳、森口　尚
- Journal Title
  
  Precision Medicine
  
  Volume: 2 Pages: 38-41
- Data Source
  KAKENHI-PROJECT-19K07388
[Journal Article] Spiral ganglion cell degeneration-induced deafness as a consequence of reduced GATA factor activity2019
- Author(s)
  Hoshino Tomofumi, Terunuma Tsumoru, Takai Jun, Uemura Satoshi, Nakamura Yasuhiro, Hamada Michito, Takahashi Satoru, Yamamoto Masayuki, Engel James Douglas and Moriguchi Takashi
- Journal Title
  
  Genes to cells
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05147
[Journal Article] 転写因子GATA2と免疫不全症2019
- Author(s)
  高井淳、森口尚
- Journal Title
  
  Precision Medicine
  
  Volume: 2 Pages: 38-41
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Journal Article] Spiral ganglion cell degeneration-induced deafness as a consequence of reduced GATA factor activity2019
- Author(s)
  Tomofumi Hoshino, Tsumoru Terunuma, Jun Takai, Satoshi Uemura, Yasuhiro Nakamura, Michito Hamada, Satoru Takahashi, Masayuki Yamamoto, James Douglas Engel, TakashiMoriguchi
- Journal Title
  
  Genes to cells
  
  Volume: 印刷中
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Journal Article] A Gata3 3′ Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression2018
- Author(s)
  Moriguchi Takashi、Hoshino Tomofumi、Rao Arvind、Yu Lei、Takai Jun、Uemura Satoshi、Ise Kazue、Nakamura Yasuhiro、Lim Kim-Chew、Shimizu Ritsuko、Yamamoto Masayuki、Engel James Douglas
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 38 Issue: 21 Pages: 21-21
- DOI
  10.1128/mcb.00302-18
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05041, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-15H04759, KAKENHI-PROJECT-16H05147
[Journal Article] Reducing Inflammatory Cytokine Production from Renal Collecting Duct Cells by Inhibiting GATA2 Ameliorates Acute Kidney Injury.2017
- Author(s)
  Yu L, Moriguchi T, Kaneko H, Hayashi M, Hasegawa A, Nezu M, Saya H, Yamamoto M, Shimizu R.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 37 Issue: 22 Pages: 211-217
- DOI
  10.1128/mcb.00211-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-15H04759, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-17J04895
[Journal Article] Transcription Factor MafB Coordinates Epidermal Keratinocyte Differentiation.2017
- Author(s)
  Miyai M, Hamada M, Moriguchi T, Hiruma J, Kamitani-Kawamoto A, Watanabe H, Hara-Chikuma M, Takahashi K, Takahashi S, Kataoka K.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 136 Issue: 9 Pages: 1848-1857
- DOI
  10.1016/j.jid.2016.05.088
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-15K09747, KAKENHI-PROJECT-16K09763
[Journal Article] Derepression of the DNA Methylation Machinery of the <i>Gata1</i> Gene Triggers the Differentiation Cue for Erythropoiesis2017
- Author(s)
  Yu L, Takai J, Otsuki A, Katsuoka F, Suzuki M, Katayama S, Nezu M, Engel JD, Moriguchi T, Yamamoto M.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 37 Issue: 8 Pages: 592-616
- DOI
  10.1128/mcb.00592-16
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-15H06037, KAKENHI-PROJECT-16H07149, KAKENHI-INTERNATIONAL-15K21759
[Journal Article] GATA3 is essential for the maintenance of mesangial cell2016
- Author(s)
  Takashi Moriguchi, Lei Yu, Akihito Otsuki, Keiko Ainoya, Kim-Chew Lim, Masayuki Yamamoto and James Douglas Engel
- Journal Title
  
  Mol Cell Biol
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24590371
[Journal Article] Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription.2016
- Author(s)
  Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, Tanaka N, Moriguchi T, Motohashi H, Nakayama K, Yamamoto M.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Issue: 1 Pages: 11624-11624
- DOI
  10.1038/ncomms11624
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K08257, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-16K15228
[Journal Article] NRF2 intensifies host defense systems to prevent lung carcinogenesis, but after tumor initiation accelerates malignant cell growth.2016
- Author(s)
  Satoh H, Moriguchi T, Saigusa D, Baird L, Yu L, Rokutan H, Igarashi K, Ebina M, Shibata T, Yamamoto M.
- Journal Title
  
  Cancer Res.
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24590371
[Journal Article] Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect.2016
- Author(s)
  Moriguchi T, Yu L, Otsuki A, Ainoya K, Lim KC, Yamamoto M, Engel JD.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 36 Issue: 17 Pages: 2272-2281
- DOI
  10.1128/mcb.00173-16
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-16H07149
[Journal Article] Versatile activity of the master regulator of the antioxidant response in tumor initiation, progression and metastasis2016
- Author(s)
  Moriguchi T
- Journal Title
  
  Cancer Cell & Microenvironment
  
  Volume: 3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05147
[Journal Article] The Human GATA1 Gene Retains a 5' Insulator That Maintains Chromosomal Architecture and GATA1 Expression Levels in Splenic Erythroblasts.2015
- Author(s)
  Moriguchi T, Yu L, Takai J, Hayashi M, Satoh H, Suzuki M, Ohneda K, Yamamoto M.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 35 Issue: 10 Pages: 1825-1837
- DOI
  10.1128/mcb.00011-15
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590359, KAKENHI-PUBLICLY-25118722, KAKENHI-PROJECT-15K08285, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-26670463
[Journal Article] Whole-body in vivo monitoring of inflammatory diseases exploiting human interleukin 6-luciferase transgenic mice2015
- Author(s)
  Hayashi M, Takai J, Yu L, Motohashi H, Moriguchi T, Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 35 Issue: 20 Pages: 3590-3601
- DOI
  10.1128/mcb.00506-15
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-26670150
[Journal Article] Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation.2015
- Author(s)
  Nadine Keleku-Lukwete, Mikiko Suzuki, Akihito Otsuki, Kouhei Tsuchida, Saori Katayama, Makiko Hayashi, Eriko Naganuma, Takashi Moriguchi, Osamu Tanabe, James Douglas Engel, Masue Imaizumi, Masayuki Yamamoto
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 112 Issue: 39 Pages: 12169-12174
- DOI
  10.1073/pnas.1509158112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460355, KAKENHI-PROJECT-26461395, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-26670463
[Journal Article] A regulatory network governing Gata1 and Gata2 gene transcription orchestrates erythroid lineage differentiation.2014
- Author(s)
  Moriguchi T, Yamamoto M.
- Journal Title
  
  Int J Hematol.
  
  Volume: 100 Issue: 5 Pages: 417-424
- DOI
  10.1007/s12185-014-1568-0
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142
[Journal Article] Indoxyl sulfate down-regulates SLCO4C1 transporter through up-regulation of GATA32014
- Author(s)
  Yu L, Moriguchi T, Souma T, Takai J, Satoh H, Morito N, Engel JD, Yamamoto M
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 8 Issue: 11 Pages: 1929-1941
- DOI
  10.1128/mcb.01659-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J07924, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591223, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-26860623
[Journal Article] GATA4 immunolocalization in breast carcinoma as a potent prognostic predictor.2014
- Author(s)
  Takagi K, Moriguchi T, Miki Y, Nakamura Y, Watanabe M, Ishida T, Yamamoto M, Sasano H, Suzuki T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Issue: 5 Pages: 600-607
- DOI
  10.1111/cas.12382
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-25460410
[Journal Article] Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3.2014
- Author(s)
  Udager AM, Prakash A, Saenz DA, Schinke M, Moriguchi T, Jay PY, Lim KC, Engel JD, Gumucio DL.
- Journal Title
  
  Gastroenterology.
  
  Volume: 146 Issue: 1 Pages: 157-165
- DOI
  10.1053/j.gastro.2013.10.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590371
[Journal Article] MafB promotes atherosclerosis by inhibiting foam-cell apoptosis2014
- Author(s)
  Hamada M, Nakamura M, Tran MT, Moriguchi T, Hong C, Ohsumi T, Dinh TT, Kusakabe M, Hattori M, Katsumata T, Arai S, Nakashima K, Kudo T, Kuroda E, Wu CH, Kao PH, Sakai M, Shimano H, Miyazaki T, Tontonz P, Takahashi S
- Journal Title
  
  Nat Commun
  
  Volume: 5 Issue: 1 Pages: 3147-3147
- DOI
  10.1038/ncomms4147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21220009, KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-24390230, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591145, KAKENHI-PUBLICLY-25126701, KAKENHI-PROJECT-25253056, KAKENHI-PROJECT-25461494, KAKENHI-PROJECT-26220207, KAKENHI-PROJECT-26670448
[Journal Article] Overexpression of Mafb in Podocytes Protects against Diabetic Nephropathy.2014
- Author(s)
  Morito N, Yoh K, Ojima M, Okamura M, Nakamura M, Hamada M, Shimohata H, Moriguchi T, Yamagata K, Takahashi S.
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: 印刷中 Issue: 11 Pages: 2546-2557
- DOI
  10.1681/asn.2013090993
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591223, KAKENHI-PROJECT-25860205
[Journal Article] Myeloid lineage-specific deletion of antioxidant system enhances tumor metastasis.2014
- Author(s)
  Hiramoto K, Satoh H, Suzuki T, Moriguchi T, Pi J, Shimosegawa T, Yamamoto M.
- Journal Title
  
  Cancer Prev Res (Phila).
  
  Volume: 7 Pages: 835-844
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590371
[Journal Article] [Network regulation of Gata1 and Gata2 gene-dynamics underlies erythroid differentiation].2014
- Author(s)
  Moriguchi T, Yamamoto M.
- Journal Title
  
  Rinsho Ketsueki.
  
  Volume: 55 Pages: 633-642
- NAID
  130004501870
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590371
[Journal Article] Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice.2014
- Author(s)
  Ohneda K, Moriguchi T, Ohmori S, Ishijima Y, Satoh H, Philipsen S, Yamamoto M.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 34 Issue: 10 Pages: 1812-1826
- DOI
  10.1128/mcb.01524-13
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590359, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142, KAKENHI-PUBLICLY-25118722, KAKENHI-PROJECT-25860221
[Journal Article] Establishment of erythroleukemic GAK14 cells and characterization of GATA1 N-terminal domain2013
- Author(s)
  Mukai HY, Suzuki M, Nagano M, Ohmori S, Otsuki A, Tsuchida K, Moriguchi T, Ohneda K, Shimizu R, Ohneda O, Yamamoto M,
- Journal Title
  
  Genes Cells
  
  Volume: 18 Issue: 10 Pages: 886-898
- DOI
  10.1111/gtc.12084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24590359, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456, KAKENHI-PROJECT-24790735, KAKENHI-PROJECT-24790957, KAKENHI-PUBLICLY-25118722, KAKENHI-PROJECT-25860221
[Journal Article] Nrf2 prevents tumor-initiation but accelerates malignant transformation in lung carcinogenesis through the Kras-signaling pathway.2013
- Author(s)
  Satoh H, Moriguchi T, Takai J, Ebina M, and Yamamoto M.
- Journal Title
  
  Cancer Research
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590371
[Journal Article] Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis.2013
- Author(s)
  Satoh H, Moriguchi T, Takai J, Ebina M, Yamamoto M.
- Journal Title
  
  Cancer Res
  
  Volume: 73 Pages: 4158-4168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590371
[Journal Article] Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis.2013
- Author(s)
  Satoh H, Moriguchi T, Takai J, Ebina M, Yamamoto M.
- Journal Title
  
  Cancer Research
  
  Volume: 73(13) Pages: 4158-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870071
[Journal Article] The nuclear factor erythroid 2-related factor 2 activator oltipraz attenuates chronic hypoxia-induced cardiopulmonary alterations in mice.2013
- Author(s)
  Eba S, Hoshikawa Y, Moriguchi T, Mitsuishi Y, Satoh H, Ishida K, Watanabe T, Shimizu T, Shimokawa H, Okada Y, Yamamoto M, Kondo T
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 49(2 Issue: 2 Pages: 324-333
- DOI
  10.1165/rcmb.2011-0396oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592052, KAKENHI-PROJECT-24590371
[Journal Article] Plasticity of renal erythropoietin-producing cells governs fibrosis2013
- Author(s)
  Souma T, Yamazaki S, Moriguchi T, Suzuki N, Hirano I, Pan X, Minegishi N, Abe M, Kiyomoto H, Ito S, Yamamoto M
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 24 Issue: 10 Pages: 1599-1616
- DOI
  10.1681/asn.2013010030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24116502, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591187, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-25462533, KAKENHI-PROJECT-25670157
[Journal Article] The Gatal 5' region harbors distinct cis-regulatory modules that direct gene activation in erythroid cells and gene inactivation in HSCs2013
- Author(s)
  Takai J, Moriguchi T, Suzuki M, Yu L, Ohneda K, and Yamamoto M.
- Journal Title
  
  Blood.
  
  Volume: 122 Issue: 20 Pages: 3450-3460
- DOI
  10.1182/blood-2013-01-476911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06534, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24590359, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24790957, KAKENHI-PUBLICLY-25118722
[Journal Article] GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation2013
- Author(s)
  Suzuki M, Kobayashi-Osaki M, Tsutsumi S, Pan X, Ohmori S, Takai J, Moriguchi T, Ohneda O, Ohneda K, Shimizu R, Kanki Y, Kodama T, Aburatani H, Yamamoto M
- Journal Title
  
  Genes Cells
  
  Volume: 18 Issue: 11 Pages: 921-933
- DOI
  10.1111/gtc.12086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24590359, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456, KAKENHI-PROJECT-24710227, KAKENHI-PROJECT-24790957, KAKENHI-PUBLICLY-25118709, KAKENHI-PUBLICLY-25118722, KAKENHI-PUBLICLY-25125707, KAKENHI-PROJECT-25440007, KAKENHI-PROJECT-25860221
[Journal Article] UG4 enhancer-driven GATA-2 and bone morphogenetic protein 4 complementation remedies the CAKUT phenotype in Gata2 hypomorphic mutant mice2012
- Author(s)
  Ainoya K, Moriguchi T, Ohmori S, Souma T, Takai J, Morita M, Chandler KJ, Mortlock DP, Shimizu R, Engel JD, Lim KC, Yamamoto M.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 32 Issue: 12 Pages: 2312-2322
- DOI
  10.1128/mcb.06699-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07924, KAKENHI-PROJECT-21390288, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456
[Journal Article] Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation2012
- Author(s)
  Xue M, Rabbani N, Momiji H, Imbasi P, Anwar MM, Kitteringham N, Park BK, Souma T, Moriguchi T, Yamamoto M, Thornalley PJ.
- Journal Title
  
  Biochemical Journal
  
  Volume: 443 Issue: 1 Pages: 213-222
- DOI
  10.1042/bj20111648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07924, KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22590260, KAKENHI-PROJECT-24590371
[Journal Article] The regulation of GATA factor expression is distinct between erythroid and mast cell lineages.2012
- Author(s)
  Ohmori S, Takai J, Ishijima Y, Suzuki M,　Moriguchi T, Philipsen S, Yamamoto M, Ohneda K.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 32 Issue: 23 Pages: 4742-4755
- DOI
  10.1128/mcb.00718-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590359, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24790957, KAKENHI-PUBLICLY-23118525
[Journal Article] Luminal alkalinization attenuates proteinuria-induced oxidative damage in proximal tubular cells2011
- Author(s)
  Souma T, Abe M, Moriguchi T, Takai J, Yanagisawa-Miyazawa N, Shibata E, Akiyama Y, Toyohara T, Suzuki T, Tanemoto M, Abe T, Sato H, Yamamoto M, Ito S
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 22 Issue: 4 Pages: 635-648
- DOI
  10.1681/asn.2009111130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06534, KAKENHI-PROJECT-22590199, KAKENHI-PROJECT-22590260, KAKENHI-PROJECT-22790144, KAKENHI-PROJECT-23590265, KAKENHI-PROJECT-23591224
[Journal Article] MafB interacts with Gcm2 and regulates parathyroid hormone expression and parathyroid development2011
- Author(s)
  Kamitani-Kawamoto A, Hamada M, Moriguchi T, Miyai M, Hitoshi S, Ikenaka K, Hosoya T, Hotta Y, Takahashi S, Kataoka K
- Journal Title
  
  J Bone Mineral Res
  
  Volume: 26 Issue: 10 Pages: 2463-2472
- DOI
  10.1002/jbmr.458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220009, KAKENHI-PLANNED-22115004, KAKENHI-PROJECT-22590260, KAKENHI-PROJECT-22590982
[Journal Article] Luminal alkalization attenuates superoxide production induced by fatty acid-bound albumin in renal proximal tubular cells through Pyk2-dependent pathways2011
- Author(s)
  Souma T, Abe M, Moriguchi T, Yanagisawa-Miyazawa N, Shibata E, Akiyama Y, Toyohara T, Suzuki T, Tanemoto M, Abe T, Sato H, Yamamoto M, Ito S
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: (未定)(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] A NK and T cell enhancer lies 280kbp 3' to the Gata3 structural gene.2011
- Author(s)
  Hosoya-Ohmura S, Lin Y-H, Kuroha T, Rao A, Moriguchi T, Lim K-C,Hosoya T, Engel JD.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590260
[Journal Article] Luminal aikalization attenuate superoxide production induced by Fatty acid-bound albumin in renal proximal tubular cells through Pyk2-dependent pathway.2011
- Author(s)
  Souma T, Abe M, Moriguchi T, Shibata E, Miyazawa N, Akiyoshi Y, Toyohara T, Suzuki T, Tanemoto M, Abe T, Sato H, Cowley AW, Yamamoto M, Ito S.
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590260
[Journal Article] An NK and T cell enhancer lies 280 kilobase pairs 3' to the gata3 structural gene2011
- Author(s)
  Hosoya-Ohmura S, Lin YH, Herrmann M, Kuroha T, Rao A, Moriguchi T, Lim KC, Hosoya T, Engel JD
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31 Issue: 9 Pages: 1894-1904
- DOI
  10.1128/mcb.05065-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590260
[Journal Article] Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung.2010
- Author(s)
  Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT Jr, Raman V, Ebina M, Nukiwa T, Yamamoto M.
- Journal Title
  
  Carcinogenesis
  
  Volume: 31 Pages: 1833-1843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590260
[Journal Article] Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung2010
- Author(s)
  Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT Jr, Raman V, Ebina M, Nukiwa T, Yamamoto M
- Journal Title
  
  Carcinogenesis
  
  Volume: 31 Pages: 1833-1843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Gata1遺伝子発現制御領域の血球分化段階特異的な機能的貢献2009
- Author(s)
  森口尚
- Journal Title
  
  東北医学会雑誌 120
  
  Pages: 193-196
- NAID
  120003660438
- Data Source
  KAKENHI-PROJECT-19770187
[Journal Article] Differential Contribution of the Gata1 Gene Hematopoietic to Erythroid Differentiation2009
- Author(s)
  Suzuki M, Moriguchi T, Ohneda K and Yamamoto M
- Journal Title
  
  Mol Cell Biol 29
  
  Pages: 1163-1175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770187
[Journal Article] Transcription Factor Networks SpecifySympathetic and Adrenal ChromaffinCell Differentiation2007
- Author(s)
  Moriguchi, T, Lim, K-C, and Engel J. D.
- Journal Title
  
  Functional Development and Embryology 1
  
  Pages: 130-135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770187
[Journal Article] GATA-3 is required for definitive nephrogenesis.2007
- Author(s)
  Hasegawa SL, Moriguchi T, Rao A, Kuroha T, Grosveld F, Engel JD and Lim KC.
- Journal Title
  
  Developmental Biology 301
  
  Pages: 568-577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770187
[Journal Article] GATA-3 is required for definitive nephrogenesis2007
- Author(s)
  Hasegawa SL, Moriguchi T, Rao A, Kuroha T, Grosveld F, Engel JD and Lim KC
- Journal Title
  
  Dev Biol 301
  
  Pages: 568-577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770187
[Journal Article] Transcription Factor Networks Specify Sympathetic and Adrenal Chromaffin Cell Differentiation.2007
- Author(s)
  Moriguchi T, Lim KC and Engel JD.
- Journal Title
  
  Functional Development and Embryology 1
  
  Pages: 130-135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770187
[Journal Article] GATA1 and GATA2 function in hematopoietic differentiation
- Author(s)
  Moriguchi T, Suzuki M, Engel JD and Yamamoto M
- Journal Title
  
  Hematopoietic Stem Cell Biology(The Human Press Inc) (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770187
[Journal Article] c-Maf is essential for F4/80 expression in macrophages
- Author(s)
  Nakamura M, Hamada M, Kusakabe M, Hasegawa K, Suzuki H, Greaves, DR, Moriguchi T, Kudo T, Takahahi S.
- Journal Title
  
  in vivo. Gene (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770187
[Journal Article] Transcription factor GATA-3 is essential for lens development
- Author(s)
  Maeda A, Moriguchi T*, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim K-C, Engel JD, Takahashi S
- Journal Title
  
  Dev Dyn (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770187
[Presentation] Gata2ヘテロ変異のリンパ管再疎通遅延の要因とコラーゲン添加による再疎通改善効果2023
- Author(s)
  浅香智美、林もゆる、高井　淳、上村聡志、森口　尚、河合佳子
- Organizer
  第47回日本リンパ学会総会
- Data Source
  KAKENHI-PROJECT-22K06913
[Presentation] 転写因子GATA2は炎症関連遺伝子座のクロマチン構造を変換し発現活性化に寄与する2023
- Author(s)
  高井淳, 植木陽向, 大森慎也, 大根田絹子, 上村聡志, 森口尚
- Organizer
  日本生化学会東北支部第89回例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06913
[Presentation] Gata2ヘテロ欠損マウスにおけるリンパ管再疎通障害を惹起するコラーゲン代謝異常について2023
- Author(s)
  河合佳子、浅香智美，林もゆる，高井　淳，上村聡志，中村保宏，森口　尚
- Organizer
  第64回日本脈管学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06913
[Presentation] リンパ管再疎通におけるGata2ヘテロ変異と線維芽細胞の関与2023
- Author(s)
  原田拓弥, 浅香智美, 林もゆる, 高井淳, 上村聡志, 森口尚, 河合住子
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K06913
[Presentation] リンパ管再疎通におけるGata2ヘテロ変異と線維芽細胞の関与2023
- Author(s)
  原田拓弥，浅香智美，林もゆる，高井　淳，上村聡志，森口　尚，河合佳子
- Organizer
  第55回東北生理学懇話会
- Data Source
  KAKENHI-PROJECT-22K06913
[Presentation] Fut8ヘテロノックアウトマウスにおいてL-フコース投与はリポ多糖による神経炎症を抑制する2023
- Author(s)
  徐興, 福田友彦, 高井淳, 中ノ三弥子, 森口尚, 顧建国
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06913
[Presentation] 転写因子GATA2は炎症関連遺伝子を制御する2022
- Author(s)
  高井淳, 大森慎也, 大根田絹子, 上村聡志, 森口尚
- Organizer
  日本生化学会東北支部第88回例会
- Data Source
  KAKENHI-PROJECT-22K06913
[Presentation] HDCレポーターマウスの樹立と炎症刺激に応答して増加するヒスタミン産生好中球の解析.2022
- Author(s)
  高井淳, 森口尚
- Organizer
  第23回日本ヒスタミン学会
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] Gata2ヘテロマウスにおけるリンパ管再疎通遅延の原因解明に向けた新たな取り組み2022
- Author(s)
  浅香智美, 林もゆる, 高井淳, 上村聡志, 森口尚, 河合佳子
- Organizer
  第46回日本リンパ学会総会
- Data Source
  KAKENHI-PROJECT-22K06913
[Presentation] マスト細胞における転写因子GATA2の高度転写活性化機序の解析2022
- Author(s)
  大森慎也, 高井淳, 森口尚, 森哲哉, 大根田絹子
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06913
[Presentation] 研究機器の学際共同利用について2021
- Author(s)
  森口尚
- Organizer
  先端研究基盤共用促進事業新共用＆SHARE利用報告会
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] マウスマスト細胞における新規Il6遺伝子制御領域(Il6-DRE)の同定と解析2021
- Author(s)
  大森慎也, 森口尚, 高井淳, 森哲哉, 大根田絹子
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] 温故知新;古くて新しいGATA転写因子研究の最前線炎症制御因子としてのGATA22021
- Author(s)
  高井淳, 大森慎也, 大根田絹子, 上村聡志, 山本雅之, 森口尚
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] 転写因子GATA2のヘテロ変異マウスは炎症反応と細菌排泄能の低下を示す2021
- Author(s)
  高井淳, 島田昂志, 中村正帆, James Douglas Engel, 森口尚.
- Organizer
  日本生化学会東北支部第87 回例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] LPS刺激に応答して増加するヒスタミン産生好中球の同定と解析2020
- Author(s)
  高井淳, 上村聡志、森口尚
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] GATA2 provokes inflammation and infectous immunity via direct regulation of inflammatory cytokine genes2019
- Author(s)
  高井淳、島田昴志、大津浩、山本雅之、上村聡志、森口尚
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] GATA2へテロ欠損マウスの炎症モニターリング2019
- Author(s)
  島田昂志、高井淳、上村聡志、山本雅之、森口尚
- Organizer
  日本生化学会東北支部第85回例会
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] GATA2 provokes inflammation and infectous immunity via direct regulation of inflammatory cytokine genes2019
- Author(s)
  高井淳、島田昴志、大津浩、山本雅之、上村聡志、森口尚
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] GATA2によるサイトカイン産生亢進を介した炎症促進メカニズム2019
- Author(s)
  森口尚
- Organizer
  新学術領域予防を科学する炎症細胞社会学班会議.(招待講演)
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] リンパ節切除後の再疎通現象におけるGata2遺伝子の及ぼす影響について2019
- Author(s)
  鈴木紅音、浅香智美、林もゆる、高井淳、上村聡志、森口尚、河合佳子
- Organizer
  第51回東北生理談話会
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] ヒスタミン合成酵素レポーターマウスの樹立とリポ多糖刺激に応答して増加するヒスタミン合成酵素陽性好中球の同定.2019
- Author(s)
  高井淳、島田昴志、大津浩、山本雅之、上村聡志、森口尚
- Organizer
  日本生化学会東北支部第85回例会
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] 副腎髄質交感神経系でのGATA2機能解析2019
- Author(s)
  浅香智美，河合佳子，森口尚
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] 副腎髄質交感神経系でのGATA2機能解析2019
- Author(s)
  浅香智美，河合佳子，森口尚
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] GATA2によるサイトカイン産生亢進を介した炎症促進メカニズム2019
- Author(s)
  森口尚
- Organizer
  新学術領域予防を科学する炎症細胞社会学　班会議.
- Invited
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] 2.ヒスタミン合成酵素レポーターマウスの樹立とリポ多糖刺激に応答して増加するヒスタミン合成酵素陽性好中球の同定.2019
- Author(s)
  高井淳、島田昴志、大津浩、山本雅之、上村聡志、森口尚
- Organizer
  日本生化学会東北支部第85回例会.
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] リンパ節切除後の再疎通現象におけるGata2遺伝子の及ぼす影響について2019
- Author(s)
  鈴木　紅音、浅香　智美、林　もゆる、高井　淳、上村　聡志、森口　尚、河合　佳子
- Organizer
  第51回　東北生理談話会
- Data Source
  KAKENHI-PROJECT-19K07388
[Presentation] GATA2へテロ欠損マウスの炎症モニターリング2019
- Author(s)
  島田昂志、高井淳、上村聡志、山本雅之、森口尚
- Organizer
  日本生化学会東北支部第85回例会
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] ヒスチジン脱炭酸酵素レポーターマウスを用いたアレルギー・炎症反応のイメージングの試み2018
- Author(s)
  高井淳、島田昂志、森口尚、大津浩、山本雅之
- Organizer
  In vivoイメージングフォーラム2018
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] A Gata3 3' distal otic vesicle enhancer directs inner ear-specific Gata3 expression2018
- Author(s)
  森口尚, 山本雅之, エンゲルジェームスダグラス
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] A Gata3 3' distal otic vesicle enhancer directs inner ear-specific Gata3 expression2018
- Author(s)
  森口尚
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] 腎集合管細胞での転写因子GATA2機能阻害による急性腎障害抑制効果2018
- Author(s)
  森口尚
- Organizer
  第９１回日本生化学会年会
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] ヒスチジン脱炭酸酵素レポーターマウスを用いたアレルギー・炎症反応のイメージングの試み2018
- Author(s)
  高井淳、島田昂志、森口尚、大津浩、山本雅之
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] 転写因子GATA3 の内耳特異的エンハンサー2018
- Author(s)
  森口尚
- Organizer
  第８４回日本生化学会東北支部会.
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] ヒスチジン脱炭酸酵素レポーターマウスを用いたヒスタミン産生細胞のイメージングの試み2018
- Author(s)
  高井淳、島田昂志、森口尚、大津浩、山本雅之
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] 腎集合管細胞での転写因子GATA2機能阻害による急性腎障害抑制効果2018
- Author(s)
  森口尚
- Organizer
  第９１回日本生化学会年会
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] 転写因子GATA3 の内耳特異的エンハンサー2018
- Author(s)
  森口尚
- Organizer
  第８４回日本生化学会東北支部会.
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] GATA2によるサイトカイン産生亢進を介した炎症促進メカニズム.2018
- Author(s)
  森口　尚
- Organizer
  新学術領域予防を科学する炎症細胞社会学　班会議.
- Invited
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] ヒスチジン脱炭酸酵素レポーターマウスを用いたアレルギー・炎症反応のイメージングの試み2018
- Author(s)
  高井淳、島田昂志、森口尚、大津浩、山本雅之
- Organizer
  In vivoイメージングフォーラム2018
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] ヒスタミン産生細胞レポーターマウスを用いたアレルギー・炎症反応のイメージング2018
- Author(s)
  高井淳、森口尚、大津浩、山本雅之
- Organizer
  新学術領域研究予防を科学する炎症細胞社会学第1回班会議
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] ヒスチジン脱炭酸酵素レポーターマウスを用いたヒスタミン産生細胞のイメージングの試み2018
- Author(s)
  高井淳、島田昂志、森口尚、大津浩、山本雅之３．学会等名
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] Histidine decarboxylase transgenic BAC DNA directs histamine producing cell-specific inducible gene expression2018
- Author(s)
  高井淳、森口尚、大津浩、山本雅之
- Organizer
  日本生化学会東北支部第84回例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] 副腎髄質交感神経系でのZnフィンガー型転写因子GATA2の生理機能2018
- Author(s)
  浅香智美，河合佳子，森口尚
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] ヒスタミン産生細胞レポーターマウスを用いたアレルギー・炎症反応のイメージング2018
- Author(s)
  高井淳、森口尚、大津浩、山本雅之
- Organizer
  第67回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] ヒスタミン産生細胞レポーターマウスを用いたアレルギー・炎症反応のイメージング2018
- Author(s)
  高井淳、森口尚、大津浩、山本雅之
- Organizer
  第67回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] ヒスチジン脱炭酸酵素レポーターマウスを用いたアレルギー・炎症反応のイメージングの試み2018
- Author(s)
  高井淳、島田昂志、森口尚、大津浩、山本雅之
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PUBLICLY-18H05041
[Presentation] 副腎髄質交感神経系でのZnフィンガー型転写因子GATA2の生理機能2018
- Author(s)
  浅香智美，河合佳子，森口尚
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] 生体防御因子Nrf2の遺伝的および薬剤誘導的活性化は多発性硬化症の症状を改善する2016
- Author(s)
  林真貴子, 森口尚, 鈴木未来子, 小林枝里, 山本雅之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect.2016
- Author(s)
  森口尚, 山本雅之, エンゲルジェームスダグラス
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] 転写因子GATA3低発現マウスはメサンギウム増殖性糸球体腎炎を呈する2016
- Author(s)
  森口尚, 于磊, 大槻晃史, 山本雅之. エンゲルジェームスダグラス
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] 抗酸化ストレス転写因子Nrf2過剰発現マウスの著明な肺発癌抑制能を誘導する機構2016
- Author(s)
  佐藤大希, 森口尚, 六反啓文, 海老名雅人, 柴田龍弘, 山本雅之
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H05147
[Presentation] 転写因子GATA2の腎集合管での生理機能について2015
- Author(s)
  森口　尚
- Organizer
  第1回川島カンファランス
- Place of Presentation
  岐阜、内藤記念博物館大ホール
- Year and Date
  2015-11-15
- Invited
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] Mechanisms of Gata1 gene inactivation in hematopoietic stem cells2015
- Author(s)
  森口　尚
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸、神戸国際会議場
- Year and Date
  2015-12-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] Gata1とGata2 遺伝子のネットワーク制御を基盤とした赤血球分化の分子機構2015
- Author(s)
  森口　尚
- Organizer
  日本生化学会東北支部会
- Place of Presentation
  仙台、東北大学片平さくらホール
- Year and Date
  2015-05-11
- Invited
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] 転写因子 GATA2 の尿細管細胞での生理機能.2014
- Author(s)
  森口　尚
- Organizer
  第８０回日本生化学会東北支部会
- Place of Presentation
  秋田県秋田市・アキタパークホテル
- Year and Date
  2014-05-11
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] 赤血球系転写因子GATA1の造血幹細胞での発現抑制メカニズム.2014
- Author(s)
  森口　尚
- Organizer
  第10回麒麟塾
- Place of Presentation
  東京都品川区・コクヨホール.
- Year and Date
  2014-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] Transcription factor GATA2 regulates body-water homeostasis through maintaining Aquaporin 2 expression in the renal collecting duct.2013
- Author(s)
  Yu Lei, 相馬友和, 山本雅之, 森口　尚
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] Nrf2ノックアウトマウスはウレタン投与による肺癌形成が阻害され、形成されたNrf2欠損癌結節はNudeマウスへの著しい生着不全を示す2012
- Author(s)
  佐藤大希、森口尚、守田匡伸、海老名雅仁、山本雅之
- Organizer
  平成23年度「個体レベルでのがん研究支援活動」ワークショップ
- Place of Presentation
  滋賀
- Year and Date
  2012-01-18
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 腎エリスロポイエチン産生細胞の機能的可塑性と腎内炎症環境2012
- Author(s)
  相馬友和、山崎舜、森口尚、平野育生、Pan Xiaoqing、鈴木教郎、阿部倫明、峯岸直子、伊藤貞嘉、山本雅之
- Organizer
  文部科学省・科学研究費補助金・新学術領域研究「修飾シグナル病」第二回公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-01-29
- Data Source
  KAKENHI-PROJECT-22590260
[Presentation] 転写因子GATA2と尿管膀胱接合部の正常な形成2011
- Author(s)
  山本雅之, 相野谷慶子, 森口尚
- Organizer
  第20回日本小児泌尿器科学会
- Place of Presentation
  秋田
- Year and Date
  2011-07-13
- Data Source
  KAKENHI-PROJECT-22590260
[Presentation] 転写因子Nrf2欠損はウレタン誘導性肺発癌を減少させ、Nrf2欠損癌組織は免疫不全マウスで著しい生着不全と増殖能低下をきたす2011
- Author(s)
  佐藤大希、森口尚、田口恵子、海老名雅仁、貫和敏博、山本雅之
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] GATA2 function in Urogenital development2011
- Author(s)
  Takashi Moriguchi
- Organizer
  Winter Camp of GCOE 2011 -The Cultivation for New Generation of Scientists-
- Place of Presentation
  Akiu, Sendai city, Japan
- Data Source
  KAKENHI-PROJECT-22590260
[Presentation] Differential contribution of the Gatal gene hematopoietic enhancer to the erythroid and mast cell lineages2011
- Author(s)
  Ohmori Synya, Yasushi Ishijima, Takashi Moriguchi, Sjaak Philipsen, Masayuki Yamamoto, Kinuko Ohneda
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22590260
[Presentation] 尿細管管腔内アルカリ化は蛋白尿による近位尿細管細胞酸化ストレスをPyk2経路を介して改善させる2011
- Author(s)
  相馬友和、阿部倫明、森口尚、高井淳、秋山泰利、豊原敬文、鈴木健弘、種本雅之、阿部高明、山本雅之、伊藤貞嘉
- Organizer
  第40回日本心脈管作動物質学会
- Place of Presentation
  高松
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-22590260
[Presentation] 転写因子Nrf2欠損はウレタン誘導性肺発癌を減少させ、Nrf2欠損癌組織は免疫不全マウスで著しい生着不全と増殖能低下をきたす2011
- Author(s)
  佐藤大希、森口尚、田口恵子、海老名雅仁、貫和敏博、山本雅之
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-12-21
- Data Source
  KAKENHI-PROJECT-22590260
[Presentation] UG4-directed GATA2 Expression is Essential for Proper Development of the Vesicoureteral Junction2011
- Author(s)
  相野谷慶子、森口尚、大森慎也、守田匡伸、清水律子、Kim-Chew Lim、James Douglas Engel、山本雅之
- Organizer
  第99回日本泌尿器科学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-22590260
[Presentation] 転写因子Nrf2は宿主肺における癌転移抑制因子である2010
- Author(s)
  佐藤大希、田口恵子、森口尚、海老名雅仁、貫和敏博、山本雅之
- Organizer
  第50回日本呼吸器学会学術総会
- Place of Presentation
  湯沢
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 宿主におけるNrf2欠損はMDSCs細胞に著明な酸化ストレスの蓄積を誘導し、肺癌転移に対して有利な微小環境を創造する2010
- Author(s)
  佐藤大希、森口尚、田口恵子、海老名雅仁、貫和敏博、山本雅之
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] GATA2 function in Urogenital development2010
- Author(s)
  Takashi Moriguchi
- Organizer
  9^<th> Japanese Biochemical Society (JBS) Bio-Frontier Symposium 2010. 5^<th> International Symposium on GATA factors.
- Place of Presentation
  Tohoku Univ, Sendai city, Japan
- Data Source
  KAKENHI-PROJECT-22590260
[Presentation] 尿細管管腔内アルカリ化は脂肪酸結合アルブミンによる近位尿細管細胞からの活性酸素産生を、Pyk2経路を介して改善する。2009
- Author(s)
  相馬友和、阿部倫明、森口尚、秋山泰利、豊原敬文、鈴木健弘、種本雅之、阿部高明、山本雅之、伊藤貞嘉
- Organizer
  Kidney Frontier 2009
- Place of Presentation
  東京
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Nrf2 acts as a novel metastasis suppressor in the lung2009
- Author(s)
  Satoh H, Taguchi K, Moriguchi T, Suzuki T, Ebina M, Nukiwa T, Yamamoto M.
- Organizer
  68回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Luminal alkalization attenuates superoxide production induced by fatty acid-bound albumin in renal proximal tubular cells through Pyk2-dependent pathways2009
- Author(s)
  Souma T, Abe M, Moriguchi T, Akiyama Y, Toyohara T, Shiwaku H, Suzuki T, Tanemoto M, Abe T, Sato H, Yamamoto M, Ito S
- Organizer
  The 1st International Symposium "Challenge to Medical Innovation"
- Place of Presentation
  仙台
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] New function of host NRF2 in lung cancer2009
- Author(s)
  佐藤大希, 田口恵子, 森口尚, 鈴木隆史, 海老名雅仁, 貫和敏博, 山本雅之
- Organizer
  Interdisciplinary Force 学生成果発表会
- Place of Presentation
  仙台
- Year and Date
  2009-08-04
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Gata1 遺伝子発現制御領域の血球分化段階特異的な機能的貢献2009
- Author(s)
  森口尚
- Organizer
  遺伝情報DECODE 湯沢ワークショップ
- Place of Presentation
  新潟
- Year and Date
  2009-01-19
- Data Source
  KAKENHI-PROJECT-19770187
[Presentation] Differential contribution of GATA1 hematopoietic enhancer to erythroid differentiation2008
- Author(s)
  森口尚、鈴木未来子、山本雅之
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19770187
[Presentation] Differential contribution of GATA1 hematopoietic enhancer to erythroid differentiation2008
- Author(s)
  Moriguchi T, Suzuki M and Yamamoto M
- Organizer
  The 21^<st> Naito Conference
- Place of Presentation
  山梨
- Year and Date
  2008-06-24
- Data Source
  KAKENHI-PROJECT-19770187
[Presentation] 大腸菌人工染色体を用いたGATA-1遺伝子の制御機構の解明2008
- Author(s)
  森口尚
- Organizer
  08'遺伝情報DECODE冬のワークショップ
- Place of Presentation
  湯沢
- Year and Date
  2008-01-24
- Data Source
  KAKENHI-PROJECT-19770187
[Presentation] GATA-1 hematopoietic enhancer confers its early erythroid progenitor-specific regulation2008
- Author(s)
  Moriguchi T, Suzuki M and Yamamoto M
- Organizer
  16th Annual Hemoglobin Switching Conference
- Place of Presentation
  モントレー、カリフォルニア
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-19770187
[Presentation] Differential contribution of GATA1 hematopoietic enhancer to erythroid differentiation2008
- Author(s)
  森口尚、鈴木未来子、山本雅之
- Organizer
  DECODE 湯沢ワークショップ
- Place of Presentation
  新潟
- Year and Date
  2008-01-21
- Data Source
  KAKENHI-PROJECT-19770187
[Presentation] GATA-1 hematopoietic enhancer confers its early erythroid progenitor-specific regulation2007
- Author(s)
  Moriguchi T, Suzuki M and Yamamoto M
- Organizer
  National University of Singapore-Tohoku University/Centre of Excellence Joint Symposium
- Place of Presentation
  シンガポール
- Year and Date
  2007-09-05
- Data Source
  KAKENHI-PROJECT-19770187
[Presentation] High affinity double GATA-binding site is indispensable for proper erythroid development2007
- Author(s)
  Moriguchi T, Suzuki M and Yamamoto M
- Organizer
  The 2nd JST-ERATO symposium
- Place of Presentation
  つくば
- Year and Date
  2007-12-21
- Data Source
  KAKENHI-PROJECT-19770187
[Presentation] Gatal hematopoietic enhancer confers its early erythroid progenitor-specific regulation (oral presentation)2007
- Author(s)
  Takashi Moriguchi
- Organizer
  National University of Singapore-Tohoku University/Centre of Excellence Joint Symposium
- Place of Presentation
  Singapore
- Year and Date
  2007-10-24
- Data Source
  KAKENHI-PROJECT-19770187
[Presentation] GATA2 in renal collecting duct cells contributes to pathogenesis of tubulointerstitial damage after ischemia reperfusion injury.
- Author(s)
  Yu L, Moriguchi T, Souma T, Takai J, Suzuki N, Yamamoto M.
- Organizer
  第11回がんとハイホキシア研究会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] 転写因子 GATA2 の尿細管特異的欠損マウスは尿濃縮障害を呈する.
- Author(s)
  Yu Lei, 森口　尚, 相馬友和, 高井淳, 山本雅之.
- Organizer
  第79回日本生化学会東北支部会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] Gata1 GdC region harbors two-way regulatory modules that direct erythroid-specific gene activation as well as gene inactivation in hematopoietic stem cells.
- Author(s)
  Takai J, Moriguchi T, Yamamoto M.
- Organizer
  18th Annual Hemoglobin Switching Conference
- Place of Presentation
  アメリカ（モントレー）
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] 転写因子Nrf2の欠損はKras経路の抑制と肺発生関連遺伝子の発現低下を介して、ウレタン誘導性肺腺癌悪性化を阻害する
- Author(s)
  佐藤大希、森口　尚、海老名雅仁、山本雅之
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] Real-time in vivo monitoring of inflammatory status exploiting human interleukin-6 BAC luciferase transgenic mice.
- Author(s)
  Takai J, Hayashi M, Moriguchi T, Motohashi H, and Yamamoto M.
- Organizer
  The 4th International conference on Environmental Response
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] 転写因子GATA2の尿細管特異的欠損マウスは尿濃縮障害を呈する
- Author(s)
  森口　尚、Yu Lei、相馬友和、高井淳、山本雅之
- Organizer
  第２３回バゾプレッシン研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] The upstream double GATA-binding site of Gata1 gene is essential for GATA1 expression in hematopoietic progenitors
- Author(s)
  Moriguchi T, Takai J, Yamamoto M.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] 低酸素肺高血圧症の病態解明の進歩
- Author(s)
  星川康、江場俊介、森口尚、光石陽一郎、佐藤大希
- Organizer
  第５２回日本呼吸器学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] 肺高血圧病態における抗酸化転写因子Nrf2の役割
- Author(s)
  江場俊介、星川康、森口尚、光石陽一郎、佐藤大希、山本雅之、近藤丘
- Organizer
  第1回日本肺循環学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] Nrf2-deficency attenuates lung adenocarcinoma progression through suppressing the Kras-oncogenic pathway as well as inactivating the lung cancer-related genes
- Author(s)
  Satoh H, Moriguchi T, Ebina M, and Yamamoto M.
- Organizer
  第５２回日本呼吸器学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590371
[Presentation] The upstream double GATA-binding site is essential for GATA1 expression in hematopoietic progenitors.
- Author(s)
  Moriguchi T, Takai J, Yamamoto M.
- Organizer
  18th Annual Hemoglobin Switching Conference
- Place of Presentation
  アメリカ（モントレー）
- Data Source
  KAKENHI-PROJECT-24590371
[]
[]

1. YAMAMOTO Masayuki (50166823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
2. KATSUOKA Fumiki (30447255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. MINEGISHI Naoko (40271895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MOTOHASHI Hozumi (00282351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. KUROKAWA Hirofumi (80359546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SUZUKI Norio (20447254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. SUZUKI Takafumi (70508308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. TAGUCHI Keiko (20466527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. MORITO Naoki (70463825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. ABE Michiaki (40400246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. SATOH Hironori (90407479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. MORITA Masanobu (10519094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 城田祐子 (20455819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 川上民裕 (20297659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小林匡洋 (70749283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 桑田亮 (10866502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 遠藤智之 (00400317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 関根弘樹 (50506285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. FUJIMURA Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. OHMORI Shinya

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
21. NEZU Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. UEMURA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. ISHIJIMA Yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. SUZUKI Mikiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 佐谷秀行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 山口芳樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 福田友彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 中の三弥子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 顧建国

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 大根田絹子

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
31. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
32. 近藤丘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 岡田克典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 星川康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 田邉修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MORIGUCHI Takashi 森口 尚

Research Projects

Research Products

Co-Researchers

Therapeutic strategy against infectious and inflammatory diseases by targeting master regulators of mast cells and eosinophilsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

好酸球性多発血管炎性肉芽腫症におけるGATA転写因子の病態への関与

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Selective ablation of mast cells and eosinophils by GATA factor inhibition for asthma therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epigenetic regulation of cytokiine gene expression underlying inflammatory diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Proinflammatory role of renal collecting duct cells in kidney diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Lung regeneration from iPS by using Nrf2 activator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GATA factor-mediated maintenance of renal functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

腎尿細管におけるGATA転写因子を介した生体恒常性維持機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Gata1 gene transcriptional regulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Mechanisms of Adaptive Responses to Food and Oxygen

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Book] Hematopoietic Stem Cell Biology2010

Author(s)

Total Pages

Publisher

Data Source

[Book] Diabetes Frontier2010

Author(s)

Publisher

Data Source

[Journal Article] Exogenous l-fucose attenuates neuroinflammation induced by lipopolysaccharide2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mtc6/Ehg2 is a novel endoplasmic reticulum-resident glycoprotein essential for high-pressure tolerance2024

Author(s)

Journal Title

DOI

MORIGUCHI Takashi 森口尚