WADA Toshiki 和田俊樹

… Alternative Names

矢部俊樹

YABE-WADA Toshiki 和田俊樹(矢部俊樹)

和田俊樹ワダトシキ

矢部俊樹

YABE Toshiki 矢部俊樹

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Researcher Number	10451634
Other IDs	https://orcid.org/0000-0002-6208-0590
Affiliation (based on the past Project Information) *help	2015 – 2022: 金沢医科大学, 医学部, 講師 2013 – 2014: 金沢医科大学, 医学部, 助教 2008 – 2009: Tohoku University, 多元物質科学研究所, 特別教育研究教員
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Functional biochemistry / General medical chemistry / Plant molecular biology/Plant physiology Except Principal Investigator Basic Section 49030:Experimental pathology-related / Immunology
Keywords	Principal Investigator サイトカイン / 蛋白質輸送 / Toll様受容体 / 自然免疫 / アレルギー / PCBP1 / Sortilin / マクロファージ / 好酸球 / TLR … More / 生体金属イオン / 転写後発現制御 / 膜蛋白質 / 転写後制御 / RNA結合蛋白質 / 光化学系 / 鉄硫黄クラスター / 葉緑体 / 鉄硫黄蛋白質 … More Except Principal Investigator 発達異常 / 脳 / 生体防御 / 炎症 / 抗原提示 / 胎生期 / 前駆細胞 / 樹状細胞 / 気管支喘息 / 好酸球 / 好塩基球 / セリンプロテアーゼインヒビター / 免疫学 / アレルギー Less

Sortilinの新規リガンド分泌機構の分子基盤とその好酸球における役割Principal Investigator
- Principal Investigator
  
  和田俊樹 (矢部俊樹)
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Kanazawa Medical University
Functional analysis of fetal dendritic cells and elucidation of inflammation-induced brain development abnormality contributed by fetal dendritic cells
- Principal Investigator
  
  ONAI Nobuyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kanazawa Medical University
Regulation mechanisms of novel cytokine production by metal trace elementsPrincipal Investigator
- Principal Investigator
  
  YABE-WADA Toshiki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kanazawa Medical University
Functional analysis of Sortilin in innate immune cellsPrincipal Investigator
- Principal Investigator
  
  YABE-WADA Toshiki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa Medical University
Analysis of the regulatory role of SLPI in the activation of basophils and eosinophils.
- Principal Investigator
  
  NAKAMURA Akira
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kanazawa Medical University
The structural basis of the Fe-S cluster biosynthesisPrincipal Investigator
- Principal Investigator
  
  YABE Toshiki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Plant molecular biology/Plant physiology
- Research Institution
  Tohoku University

All 2021 2020 2018 2017 2016 2015 2014 2013 2009 2008 Other

All Journal Article Presentation Other

[Journal Article] Detailed Structure of Mouse Interferon α2 and Its Interaction with Sortilin2021
- Author(s)
  Honoka Watanabe, Toshiki Yabe-Wada, Nobuyuki Onai, Masaki Unno
- Journal Title
  
  Journal of Biochemistry
  
  Volume: in press Issue: 2 Pages: 265-273
- DOI
  10.1093/jb/mvab038
- NAID
  40022722389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06507, KAKENHI-PROJECT-19K06550, KAKENHI-PROJECT-18H02644
[Journal Article] PCBP2 post‐transcriptionally regulates sortilin expression by binding to a C‐rich element in its 3′ UTR2020
- Author(s)
  Yabe‐Wada Toshiki、Philpott Caroline C.、Onai Nobuyuki
- Journal Title
  
  FEBS Open Bio
  
  Volume: 10 Issue: 3 Pages: 407-413
- DOI
  10.1002/2211-5463.12794
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06550, KAKENHI-PROJECT-18H02644
[Journal Article] Crystal structure of the ligand-free form of the Vps10 ectodomain of dimerized Sortilin at acidic pH.2018
- Author(s)
  Yabe-Wada T, Matsuba S, Unno M, Onai N.
- Journal Title
  
  FEBS Lett.
  
  Volume: 592 Issue: 15 Pages: 2647-2657
- DOI
  10.1002/1873-3468.13181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02644, KAKENHI-PROJECT-16K18518
[Journal Article] Identification of Secretory Leukoprotease Inhibitor As an Endogenous Negative Regulator in Allergic Effector Cells2017
- Author(s)
  Shintaro Matsuba, Toshiki Yabe-Wada, Kazuya Takeda, Tetsuya Sato, Mikita Suyama, Toshiyuki Takai, Toshiaki Kikuchi, Toshihiro Nukiwa, Akira Nakamura
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 8 Pages: 1538-1538
- DOI
  10.3389/fimmu.2017.01538
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09703, KAKENHI-PROJECT-16K18518
[Journal Article] TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin.2016
- Author(s)
  Yabe-Wada T, Matsuba S, Takeda K, Sato T, Suyama M, Ohkawa Y, Takai T, Shi H, Philpott CC, Nakamura A.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 26566-26566
- DOI
  10.1038/srep26566
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-16K09703, KAKENHI-PROJECT-16K18518
[Journal Article] Monomeric Form of Peptidylarginine Deiminase Type I Revealed by X-ray Crystallography and Small-Angle X-ray Scattering.2016
- Author(s)
  Saijo, S., Nagai, A., Kinjo, S., Mashimo, R., Akimoto, M., Kizawa, K., Yabe-Wada, T., Shimizu, N., Takahara, H., Unno, M.
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 428 Issue: 15 Pages: 3058-3073
- DOI
  10.1016/j.jmb.2016.06.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07261, KAKENHI-PROJECT-16K18518
[Journal Article] The iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase.2014
- Author(s)
  Avery G Frey, Anjali Nandal, Jong Hwan Park, Pamela M Smith, Toshiki Yabe, Moon-Suhn Ryu, Manik C Ghosh, Jaekwon Lee, Tracey A Rouault, Myung Hee Park, Caroline Philpott
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 111 Issue: 22 Pages: 8031-8036
- DOI
  10.1073/pnas.1402732111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870851
[Journal Article] Each member of the PCBP family exhibits iron chaperone activity toward ferritin2013
- Author(s)
  Sebastien Leidgens, Kimberley Z. Bullough, Haifeng Shi, Fengmin Li, Minoo Shakoury-Elizeh, Toshiki Yabe, Poorna Subramanian, Emory Hsu, Navin Natarajan, Anjali Nandal, Timothy L. Stemmler, Caroline C. Philpott
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 24 Pages: 17791-17802
- DOI
  10.1074/jbc.m113.460253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870851
[Journal Article] Structural Analysis of Arabidopsis CnfU Protein : An Iron-Sulfur Cluster Biosynthetic Scaffold in Chloroplasts2008
- Author(s)
  Toshiki Yabe, 他
- Journal Title
  
  Journal of Molecular Biology 381
  
  Pages: 160-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870002
[Journal Article] Structural Analysis of Arabidopsis CnfU Protein : An Iron-Sulfur Cluster Biosynthetic Scaffold in Chloroplasts2008
- Author(s)
  Toshiki Yabe, Eiki Yamashita, Akihiro Kikuchi, Kozo Morimoto, Atsushi Nakagawa, Tomitake Tsukihara, Masato Nakai
- Journal Title
  
  J.Mol.Biol. 381
  
  Pages: 160-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20870002
[Presentation] Detailed Structure of Mouse Interferon α2 and Its Interaction with Sortilin2021
- Author(s)
  和田俊樹，渡邊ほのか，海野昌喜，小内伸幸
- Organizer
  第85回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06550
[Presentation] 酸性条件下で2量体化するSortilinの結晶構造2018
- Author(s)
  和田俊樹，松葉慎太郎，海野昌喜，小内伸幸
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K18518
[Presentation] サイトカイン輸送に関与するSortilinの転写後発現制御機2018
- Author(s)
  和田俊樹，松葉慎太郎，小内伸幸
- Organizer
  第28回日本樹状細胞研究会
- Data Source
  KAKENHI-PROJECT-16K18518
[Presentation] ポリC結合蛋白質によるSortilinの転写後発現制御機構2017
- Author(s)
  和田俊樹、松葉慎太郎、小内伸幸
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K18518
[Presentation] A Glutaredoxin-BolA complex serves as an iron-sulfur cluster chaperone for the cytosolic cluster assembly machinery2017
- Author(s)
  Avery Frey, Dan Palenchar, Kym Zumbrennen, Toshiki Yabe, Ajay Vashisht, Justin Wildemann, James Wohlschlegel, Caroline Philpott
- Organizer
  2017 International BioIron Society Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18518
[Presentation] Involvement of poly-rC binding proteins in posttranscriptional regulation of Sortilin, the cytokine trafficking mediator2017
- Author(s)
  Toshiki Yabe-Wada, Shintaro Matsuba, Kazuya Takeda, Akira Nakamura, Caroline C Philpott, Nobuyuki Onai
- Organizer
  Cytokines 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18518
[Presentation] Involvement of poly-rC binding proteins in posttranscriptional regulation of Sortilin, the cytokine trafficking mediator2017
- Author(s)
  Toshiki Yabe-Wada, Shintaro Matsuba, Caroline C. Philpott, Nobuyuki Onai
- Organizer
  RNAフロンティアミーティング2017
- Data Source
  KAKENHI-PROJECT-16K18518
[Presentation] Structural Studies of Peptidylarginine Deiminase Type I using X-ray Crystallography and Small-angle X-ray Scattering2016
- Author(s)
  A.Nagai, S.Saijo, S.Kinjo, R.Mashimo, M.Akimoto, K.Kizawa, T.Yabe-Wada, N.Shimizu, H.Takahara, M.Unno
- Organizer
  14th International Conference of the Asian Crystallographic Association
- Place of Presentation
  Hanoi University of Science and Technology, Hanoi, Vietnam
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18518
[Presentation] X線結晶構造解析とX線小角散乱による蛋白質脱イミノ化酵素PAD1の構造2016
- Author(s)
  永井杏奈，西條慎也，金城沙弥，眞下隆太朗，秋元恵，清水伸隆，高原英成，木澤謙司，和田俊樹，海野昌喜
- Organizer
  日本結晶学会年会2016
- Place of Presentation
  茨城県立県民文化センター（茨城県水戸市）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-16K18518
[Presentation] Involvement of poly-rC binding proteins in posttranscriptional regulation of sortilin2016
- Author(s)
  T.Yabe-Wada, S.Matsuba, CC Philpott
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K18518
[Presentation] TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin2016
- Author(s)
  T.Yabe-Wada, S.Matsuba, K.Takeda, T.Sato, M.Suyama, Y.Ohkawa, H.Shi, C.C.Philpott, A.Nakamura
- Organizer
  Gordon Research Conference on Protein Processing, Trafficking and Secretion
- Place of Presentation
  Colby-Sawyer College in New London NH United States
- Year and Date
  2016-07-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18518
[Presentation] Structural Studies of Peptidylarginine Deiminase Type I using X-ray Crystallography and Small-Angle X-ray Scattering2016
- Author(s)
  A.Nagai, S.Saijo, S.Kinjo, R.Mashimo, M.Akimoto, K.Kizawa, T.Yabe-Wada, N.Shimizu, H.Takahara, M.Unno
- Organizer
  The International Symposium of Quantum Beam Science at Ibaraki University
- Place of Presentation
  Ibaraki University, Mito, JAPAN
- Year and Date
  2016-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18518
[Presentation] Functional analysis of Sortilin in plasmacytoid dendritic cells2015
- Author(s)
  和田俊樹、松葉慎太郎、武田和也、 Caroline C. Philpott、中村晃
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市白石区）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25460601
[Presentation] SLPI regulates eosinophil-mediated allergic inflammation2015
- Author(s)
  松葉慎太郎、武田和也、和田俊樹、高井俊行、中村晃
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市白石区）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25460601
[Presentation] 好塩基　球・好酸球におけるSLPIの制御機構の解明．2014
- Author(s)
  松葉慎太郎，和田俊樹，武田和也，佐藤哲也，須山幹太，高井俊行，中村晃
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  万国津梁館・沖縄県名護市
- Year and Date
  2014-07-02
- Data Source
  KAKENHI-PROJECT-25460601
[Presentation] 好塩基球・好酸球におけるSLPIの制御機構の解明2013
- Author(s)
  松葉慎太郎，和田俊樹，武田和也，佐藤哲也，須山幹太，高井俊行，中村晃
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京・ホテルニューオータニ
- Data Source
  KAKENHI-PROJECT-25870851
[Presentation] A regulatory role of secretory leukoprotease inhibitor (SLPI) in allergic effector cells.2013
- Author(s)
  Shintaro Matsuba, Toshiki Yabe-Wada, Kazuya Takeda, Toshiyuki Takai, Akira Nakamura
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉・幕張メッセ
- Data Source
  KAKENHI-PROJECT-25870851
[Presentation] The structural basis of the iron-sulfur cluster biosynthesis in plant chloroplasts2009
- Author(s)
  Toshiki Yabe, Masaki Unno, Akihiro Kikuchi, Eiki Yamashita, Toshitaka Matsui, Masato Nakai, Masao Ikeda-Saito
- Organizer
  Gordon Research Conferences on Cell Biology of Metals
- Place of Presentation
  Salve Regina University, Newport, RI, USA
- Data Source
  KAKENHI-PROJECT-20870002
[Presentation] The structural basis of the iron-sulfur cluster biosynthesis in plant chloroplasts2009
- Author(s)
  Toshiki Yabe, 他
- Organizer
  ICBIC 14
- Place of Presentation
  名古屋
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-20870002
[Presentation] 鉄硫黄クラスター生合成機構の構造基盤2009
- Author(s)
  矢部俊樹, 海野昌喜, 菊池晶裕, 山下栄樹, 松井敏高, 中井正人, 齋藤正男
- Organizer
  第42回酸化反応討論会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20870002
[Presentation] The structural basis of the iron-sulfur cluster biosynthesis in plant chloroplasts2009
- Author(s)
  Toshiki Yabe, Masaki Unno, Akihiro Kikuchi, Eiki Yamashita, Toshitaka Matsui, Masato Nakai, Masao Ikeda-Saito
- Organizer
  ICBIC 14
- Place of Presentation
  Nagoya Congress Center, Nagoya, JAPAN
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-20870002
[Presentation] 鉄硫黄蛋白質成熟化機構の構造生物学2008
- Author(s)
  矢部俊樹, 海野昌喜, 山下栄樹, 菊池晶裕, 中井正人, 齋藤正男
- Organizer
  日本生物物理学会東北支部例会
- Place of Presentation
  仙台
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-20870002
[Presentation] A regulatory role of secretory leukoprotease inhibitor (SLPI) in allergic effector cells.
- Author(s)
  Shintaro Matsuba, Kazuya Takeda, Toshiki Yabe-Wada, Toshiyuki Takai, Akira Nakamura
- Organizer
  Annual meeting of the Japanese society for immunology
- Place of Presentation
  Makuhari Messe, Chiba
- Data Source
  KAKENHI-PROJECT-25460601
[Presentation] 好塩基球・好酸球におけるSLPIの制御機構の解明
- Author(s)
  松葉慎太郎、和田俊樹、武田和也、佐藤哲也、須山幹太、高井俊行、中村　晃
- Organizer
  日本アレルギー学会秋季学術大会
- Place of Presentation
  ホテルニューオータニ・東京都
- Data Source
  KAKENHI-PROJECT-25460601
[]
[]

1. MATSUBA Shintaro (40367462)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. ONAI Nobuyuki (50323605)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. NAKAMURA Akira (20344723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. 海野昌喜 (10359549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. OHKAWA Yasuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. Wada Kei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WADA Toshiki 和田 俊樹

矢部俊樹

YABE-WADA Toshiki 和田 俊樹(矢部俊樹)

和田 俊樹 ワダ トシキ

矢部 俊樹

YABE Toshiki 矢部 俊樹

Research Projects

Research Products

Co-Researchers

Sortilinの新規リガンド分泌機構の分子基盤とその好酸球における役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of fetal dendritic cells and elucidation of inflammation-induced brain development abnormality contributed by fetal dendritic cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation mechanisms of novel cytokine production by metal trace elementsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of Sortilin in innate immune cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the regulatory role of SLPI in the activation of basophils and eosinophils.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The structural basis of the Fe-S cluster biosynthesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Detailed Structure of Mouse Interferon α2 and Its Interaction with Sortilin2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] PCBP2 post‐transcriptionally regulates sortilin expression by binding to a C‐rich element in its 3′ UTR2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal structure of the ligand-free form of the Vps10 ectodomain of dimerized Sortilin at acidic pH.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Secretory Leukoprotease Inhibitor As an Endogenous Negative Regulator in Allergic Effector Cells2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Monomeric Form of Peptidylarginine Deiminase Type I Revealed by X-ray Crystallography and Small-Angle X-ray Scattering.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase.2014

Author(s)

Journal Title

DOI

WADA Toshiki 和田俊樹

YABE-WADA Toshiki 和田俊樹(矢部俊樹)

和田俊樹ワダトシキ

矢部俊樹

YABE Toshiki 矢部俊樹