Teshima Yasushi 手嶋泰之

… Alternative Names

TESHIMA Yasushi 手嶋泰之

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Researcher Number	10457608
Other IDs
Affiliation (Current)	2025: 大分大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 大分大学, 医学部, 教授 2015 – 2021: 大分大学, 医学部, 講師 2010 – 2014: 大分大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Emergency medicine / Basic Section 55060:Emergency medicine-related / General physiology Except Principal Investigator Basic Section 90130:Medical systems-related / Basic Section 55060:Emergency medicine-related / Emergency medicine
Keywords	Principal Investigator 活性酸素種 / 虚血再灌流障害 / 心筋障害 / マイクロRNA / 心不全 / 低血糖 / 細胞内カルシウム過負荷 / 慢性心不全 / 低ナトリウム血症 / 心筋虚血再灌流障害 … More / 低ナトリウム / 電解質 / 虚血再灌流 / カルシウム過負荷 / 酸化ストレス / 血糖値変動 / 血糖変動 / 病態生理 … More Except Principal Investigator 心房細動 / 炎症 / 線維化 / 心房線維化 / 心外膜脂肪 / 血管内皮機能 / 脂肪酸 / 心臓自律神経機能 / 血糖値変動 / 冠攣性狭心症 / 多価不飽和脂肪酸 / 不飽和脂肪酸 / 血糖変動 / 冠攣縮性狭心症 / 虚血再灌流障害 / 酸化ストレス / メタボリック症候群 Less

心不全患者における無自覚低血糖の発生実態の解明と新規心不全治療戦略としての応用Principal Investigator
- Principal Investigator
  
  手嶋泰之
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Oita University
Relationship between coronary spastic angina and glycemic fluctuation
- Principal Investigator
  
  Akioka Hidefumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Oita University
Mechanisms of epicardial adipose tissue to cause atrial myocardial fibrosis and screening of compounds to suppress them
- Principal Investigator
  
  Takahashi Naohiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Oita University
Effects of hyponatremia on cardiac susceptibility to ischemia/reperfusion injuryPrincipal Investigator
- Principal Investigator
  
  TESHIMA YASUSHI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Oita University
A new strategy targeting microRNAs for cardiac protection against ischemia/reperfusion injuryPrincipal Investigator
- Principal Investigator
  
  Teshima Yasushi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Oita University
Novel Strategy to prevent ischemia/reperfusion injury that overcomes disadvantages of antioxidant agents
- Principal Investigator
  
  TAKAHASHI NAOHIKO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Oita University
Elucidation of the effect and mechanism of repeated hypoglycemiaon cardiomyocytes in an animal model of diabetes mellitusPrincipal Investigator
- Principal Investigator
  
  TESHIMA Yasushi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Oita University

All 2023 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Detection of fibrotic remodeling of epicardial adipose tissue in patients with atrial fibrillation: Imaging approach based on histological observation2021
- Author(s)
  Ishii Yumi、Abe Ichitaro、Kira Shintaro、Harada Taisuke、Takano Masayuki、Oniki Takahiro、Kondo Hidekazu、Teshima Yasushi、Yufu Kunio、Shuto Takashi、Wada Tomoyuki、Nakagawa Mikiko、Shimada Tatsuo、Asayama Yoshiki、Miyamoto Shinji、Takahashi Naohiko
- Journal Title
  
  Heart Rhythm O2
  
  Volume: 2 Issue: 4 Pages: 311-323
- DOI
  10.1016/j.hroo.2021.05.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04490, KAKENHI-PROJECT-21K12648, KAKENHI-PROJECT-21K19658
[Journal Article] Role of angiopoietin-like protein 2 in atrial fibrosis induced by human epicardial adipose tissue: Analysis using an organo-culture system2020
- Author(s)
  Kira S, Abe I, Ishii Y, Miyoshi M, Oniki T, Arakane M, Daa T, Teshima Y, Yufu K, Shimada T, Takahashi N.
- Journal Title
  
  Heart Rhythm
  
  Volume: 17 Issue: 9 Pages: 1591-1601
- DOI
  10.1016/j.hrthm.2020.04.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04490
[Journal Article] A traditional herbal medicine rikkunshito prevents angiotensin II-Induced atrial fibrosis and fibrillation2020
- Author(s)
  Zhan Yinge、Abe Ichitaro、Nakagawa Mikiko、Ishii Yumi、Kira Shintaro、Miyoshi Miho、Oniki Takahiro、Kondo Hidekazu、Teshima Yasushi、Yufu Kunio、Arakane Motoki、Daa Tsutomu、Takahashi Naohiko
- Journal Title
  
  Journal of Cardiology
  
  Volume: 76 Issue: 6 Pages: 626-635
- DOI
  10.1016/j.jjcc.2020.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04490, KAKENHI-PROJECT-17K09308
[Journal Article] Impact of Age on Gender Differences in the Acute Myocardial Infarction Onset–Weather Association　― Oita AMI Registry ―2020
- Author(s)
  Akioka Hidefumi、Yufu Kunio、Hara Masahide、Abe Ichitaro、Kondo Hidekazu、Saito Shotaro、Fukui Akira、Okada Norihiro、Shinohara Tetsuji、Teshima Yasushi、Nakagawa Mikiko、Takahashi Naohiko
- Journal Title
  
  Circulation Reports
  
  Volume: 2 Issue: 3 Pages: 152-157
- DOI
  10.1253/circrep.CR-19-0134
- NAID
  130007807318
- ISSN
  2434-0790
- Year and Date
  2020-03-10
- Language
  English
- Data Source
  KAKENHI-PROJECT-19K09398
[Journal Article] Disruption of actin dynamics regulated by Rho effector mDia1 attenuates pressure overload-induced cardiac hypertrophic responses and exacerbates dysfunction2020
- Author(s)
  Abe Ichitaro、Terabayashi Takeshi、Hanada Katsuhiro、Kondo Hidekazu、Teshima Yasushi、Ishii Yumi、Miyoshi Miho、Kira Shintaro、Saito Shotaro、Tsuchimochi Hirotsugu、Shirai Mikiyasu、Yufu Kunio、Arakane Motoki、Daa Tsutomu、Thumkeo Dean、Narumiya Shuh、Takahashi Naohiko、Ishizaki Toshimasa
- Journal Title
  
  Cardiovascular Research
  
  Volume: 117 Issue: 4 Pages: 1103-1117
- DOI
  10.1093/cvr/cvaa206
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08776, KAKENHI-PROJECT-20K07287, KAKENHI-PROJECT-19H04490
[Journal Article] 冠攣縮性狭心症と多価不飽和脂肪酸の関係における性差2020
- Author(s)
  秋岡秀文、油布邦夫、原田泰輔、米津圭佑、安部一太郎、斎藤聖多郎、福井暁、岡田憲広、篠原徹二、手嶋泰之、中川幹子、髙橋尚彦
- Journal Title
  
  心臓
  
  Volume: 52 Pages: 706-714
- NAID
  130008065376
- Data Source
  KAKENHI-PROJECT-19K09398
[Journal Article] Seasonal Variations of Weather Conditions on Acute Myocardial Infarction Onset: Oita AMI Registry2019
- Author(s)
  Akioka H, Yufu K, Teshima Y, Kawano K, Ishii Y, Abe I, Kondo H, Saito S, Fukui A, Okada N, Nagano Y, Shinohara T, Nakagawa M, Hara M, Takahashi N.
- Journal Title
  
  Heart and Vessels
  
  Volume: 34 Issue: 1 Pages: 9-18
- DOI
  10.1007/s00380-018-1213-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09398
[Journal Article] Hyponatraemia aggravates cardiac susceptibility to ischaemia/reperfusion injury.2019
- Author(s)
  Oniki T, Teshima Y, Nishio S, Ishii Y, Kira S, Abe I, Yufu K, Takahashi N.
- Journal Title
  
  Int J Exp Pathol.
  
  Volume: 100 Issue: 5-6 Pages: 350-358
- DOI
  10.1111/iep.12338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11578
[Journal Article] Interleukin-10 treatment attenuates sinus node dysfunction caused by streptozotocin-induced hyperglycaemia in mice2018
- Author(s)
  Kondo Hidekazu、Kira Shintaro、Oniki Takahiro、Gotoh Koro、Fukui Akira、Abe Ichitaro、Ikebe Yuki、Kawano Kyoko、Saito Shotaro、Aoki Kohei、Okada Norihiro、Nagano Yasuko、Akioka Hidefumi、Shinohara Tetsuji、Akiyoshi Kumiko、Masaki Takayuki、Teshima Yasushi、Yufu Kunio、Nakagawa Mikiko、Takahashi Naohiko
- Journal Title
  
  Cardiovascular Research
  
  Volume: 115 Issue: 1 Pages: 57-70
- DOI
  10.1093/cvr/cvy162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06856, KAKENHI-PROJECT-17K17055, KAKENHI-PROJECT-17K11578
[Journal Article] Role of atrial endothelial cells in the development of atrial fibrosis and fibrillation in response to pressure overload2017
- Author(s)
  Kume O, Teshima Y, Abe I, Ikebe Y, Oniki T, Kondo H, Saito S, Fukui A, Yufu K, Miura M, Shimada T, Takahashi N.
- Journal Title
  
  Cariovasc Pathology
  
  Volume: 27 Pages: 18-25
- DOI
  10.1016/j.carpath.2016.12.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462758, KAKENHI-PROJECT-15K01720
[Journal Article] Macrophage Infiltration Into the Endothelium of Atrial Tissue in Atrial Fibrillation2017
- Author(s)
  Sonoda Y, Teshima Y, Abe I, Ebata Y, Oniki T, Kira S, Kondo H, Saito S, Yufu K, Miyamoto S, Shimada T, Takahashi N
- Journal Title
  
  Circ J
  
  Volume: 81 Issue: 11 Pages: 1742-1744
- DOI
  10.1253/circj.CJ-16-1072
- NAID
  130006179780
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11578, KAKENHI-PROJECT-15K01720
[Journal Article] Hyperleptinemia Exacerbates High-Fat Diet-Mediated Atrial Fibrosis and Fibrillation.2017
- Author(s)
  Fukui A, Ikebe-Ebata Y, Kondo H, Saito S, Aoki K, Fukunaga N, Shinohara T, Masaki T, Teshima Y, Takahashi N.
- Journal Title
  
  J Cardiovasc Electrophysiol.
  
  Volume: 印刷中 Issue: 6 Pages: 702-710
- DOI
  10.1111/jce.13200
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462758, KAKENHI-PROJECT-15K01720, KAKENHI-PROJECT-15K08180, KAKENHI-PROJECT-26350896
[Journal Article] Role of atrial endothelial cells in the development of atrial fibrosis and fibrillation in response to pressure overload2017
- Author(s)
  Kume O, Teshima Y, Abe I, Ikebe Y, Oniki T, Kondo H, Saito S, Fukui A, Yufu K, Miura M, Shimada T, Takahashi N
- Journal Title
  
  Cardiovasc Pathol
  
  Volume: 27 Pages: 18-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11578
[Journal Article] Glucose Fluctuations Aggravate Cardiac Susceptibility to Ischemia/Reperfusion Injury by Modulating MicroRNAs Expression2016
- Author(s)
  Saito S, Thuc LC, Teshima Y, Nakada C, Nishio S, Kondo H, Fukui A, Abe I, Ebata Y, Saikawa T, Moriyama M, Takahashi N.
- Journal Title
  
  Circ J
  
  Volume: 80 Issue: 1 Pages: 186-195
- DOI
  10.1253/circj.CJ-14-1218
- NAID
  130005116977
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01720, KAKENHI-PROJECT-15K08405, KAKENHI-PROJECT-26462758, KAKENHI-PROJECT-15K18972
[Journal Article] Mast Cells Play an Important Role in the Pathogenesis of Hyperglycemia-Induced Atrial Fibrillation2016
- Author(s)
  Uemura K, Kondo H, Ishii Y, Kobukata M, Haraguchi M, Imamura T, Otsubo T, Ikebe-Ebata Y, Abe I, Ayabe R, Saito S, Aoki K, Nagano-Torigoe Y, Akioka H, Shinohara T, Teshima Y, Masaki T, Yufu K, Nakagawa M, Takahashi N
- Journal Title
  
  J Cardiovasc Electrophysiol
  
  Volume: - Issue: 8 Pages: 981-989
- DOI
  10.1111/jce.12995
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08180, KAKENHI-PROJECT-26462758
[Journal Article] Role of Indoxyl Sulfate as a Predisposing Factor for Atrial Fibrillation in Renal Dysfunction.2015
- Author(s)
  Aoki K, Teshima Y, Kondo H, Saito S, Fukui A, Fukunaga N, Nawata T, Shimada T, Takahashi N, Shibata H.
- Journal Title
  
  Journal of American Heart Association
  
  Volume: 4 Issue: 10
- DOI
  10.1161/jaha.115.002023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462758, KAKENHI-PROJECT-25461397
[Journal Article] Production of reactive oxygen species in the diabetic heart. Roles of mitochondria and NADPH oxidase.2014
- Author(s)
  Teshima Y et al
- Journal Title
  
  Circ J
  
  Volume: 78 Pages: 300-306
- NAID
  130003382238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592672
[Journal Article] Glucose fluctuations increase the incidence of atrial fibrillation in diabetic rats2014
- Author(s)
  Saito S, Teshima Y, Fukui A, Kondo H, Nishio S, Nakagawa M, Saikawa T, Takahashi N.
- Journal Title
  
  Cardiovascular Research
  
  Volume: 104 Issue: 1 Pages: 5-14
- DOI
  10.1093/cvr/cvu176
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462758
[Journal Article] Production of reactive oxygen species in the diabetic heart. Roles of mitochondria and NADPH oxidase2014
- Author(s)
  Teshima Y, Takahashi N, Nishio S, Saito S, Kondo H, Fukui A, Aoki K, Yufu K, Nakagawa M, Saikawa T
- Journal Title
  
  Circ J
  
  Volume: 78(2) Pages: 300-306
- NAID
  130003382238
- Data Source
  KAKENHI-PROJECT-23592672
[Journal Article] 糖変動と心疾患2013
- Author(s)
  手嶋泰之
- Journal Title
  
  刊糖尿病
  
  Volume: Vol.5, No2 Pages: 76-81
- Data Source
  KAKENHI-PROJECT-22590209
[Journal Article] Role of leptin signaling in the pathogenesis of angiotensin II-mediated atrial fibrosisand fibrillation2013
- Author(s)
  Fukui A, Takahashi N, Nakada C, Masaki T, Kume O, Shinohara T, Teshima Y, Hara M, Saikawa T
- Journal Title
  
  Circ Arrhythm Electrophysiol
  
  Volume: 6(2) Pages: 402-409
- Data Source
  KAKENHI-PROJECT-23592672
[Journal Article] Role of Leptin Signaling in the Pathogenesis of Angiotensin II-Mediated Atrial Fibrosis and Fibrillation.2013
- Author(s)
  Fukui A, Takahashi N, Nakada C, Masaki T, Kume O, Shinohara T, Teshima Y, Hara M, Saikawa T.
- Journal Title
  
  Circ Arrhythm Electrophysiol
  
  Volume: 2 Issue: 2 Pages: 402-9
- DOI
  10.1161/circep.111.000104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592672, KAKENHI-PROJECT-23790249
[Journal Article] Activation of CaMKII as a key regulator of reactive oxygen species production in diabetic rat heart2012
- Author(s)
  Nishio S, Teshima Y, Takahashi N, Thuc LC, Saito S, Fukui A, Kume O, Fukunaga N, Hara M, Nakagawa M, Saikawa T
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 52 Pages: 1103-1111
- Data Source
  KAKENHI-PROJECT-22590209
[Journal Article] Activation of CaMKII as a key regulator of reactive oxygen species production in diabetic rat heart.2012
- Author(s)
  Nishio S, Teshima Y, Takahashi N, Thuc LC, Saito S, Fukui A, Kume O, Fukunaga N, Hara M, Nakagawa M, Saikawa T.
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 52 Pages: 1103-1111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592672
[Journal Article] Establishment of a model of atrial fibrillation associated with chronic kidney disease in rats and the role of oxidative stress.2012
- Author(s)
  Fukunaga N, Takahashi N, Hagiwara S, Kume O, Fukui A, Teshima Y, Shinohara T, Nawata T, Hara M, Noguchi T, Saikawa T.
- Journal Title
  
  Heart Rhythm
  
  Volume: 12 Issue: 12 Pages: 2023-31
- DOI
  10.1016/j.hrthm.2012.08.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592672
[Journal Article] Inhibition of Na(+) -H(+) exchange as a mechanism of rapid cardioprotection by resveratrol.2012
- Author(s)
  Thuc LC, Teshima Y, Takahashi N, Nishio S, Fukui A, Kume O, Saito S, Nakagawa M, Saikawa T
- Journal Title
  
  Br J Pharmacol
  
  Volume: Epub ahead Issue: 6 Pages: 1745-1755
- DOI
  10.1111/j.1476-5381.2012.01877.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592672
[Journal Article] Activation of CaMKII as a key regulator of reactive oxygen species production in diabetic rat heart2012
- Author(s)
  Satoru Nishio, Yasushi Teshima, Tetsunori Saikawa
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: (In Press) Issue: 5 Pages: 1103-1111
- DOI
  10.1016/j.yjmcc.2012.02.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590209
[Journal Article] Candesartan restored cardiac Hsp72 expression and tolerance against reperfusion injury in hereditary insulin-resistant rats.2011
- Author(s)
  Taniguchi Y, Takahashi N, Fukui A, Nagano-Torigoe Y, Thuc LC, Teshima Y, Shinohara T, Wakisaka O, Ooie T, Murozono Y, Yufu K, Nakagawa M, Hara M, Yoshimatsu H, Saikawa T.
- Journal Title
  
  Cardiovasc Res
  
  Volume: 23 Pages: 433-435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592672
[Presentation] 血糖変動が及ぼす心筋への影響と心疾患との関連2023
- Author(s)
  手嶋泰之
- Organizer
  第70回日本臨床検査医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K09145
[Presentation] Detecting Fibrotic Remodeling of Epicardial Adipose Tissue in Patients with Atrial Fibrillation2021
- Author(s)
  Ishii Y, Abe I, harada T, Takano M, Kira S, Kondo H, Teshima Y, yufu K, Nakagawa M, Shimada T, Miyamoto S, Takahashi N.
- Organizer
  第85回日本循環器学会学術集会　3.26-28,2021.　横浜web
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04490
[Presentation] Possible Role of Endocardium of Left Atrial Appendage in Preventing the Thrombus2021
- Author(s)
  Ishii Y, Abe I, harada T, Takano M, Kondo H, Shinohara T, Teshima Y, yufu K, Nakagawa M, Shimada T, Miyamoto S, Takahashi N
- Organizer
  第85回日本循環器学会学術集会　3.26-28,2021.　横浜web
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04490
[Presentation] Role of angiopoietin-like protein 2 in atrial fibrosis induced by human epicardial adipose tissue.2020
- Author(s)
  吉良晋太朗安部一太郎, 石井悠海, 三好美帆, 鬼木崇裕, 福井暁, 篠原徹二, 手嶋泰之, 油布邦夫, 島田達夫, 中川幹子, 高橋尚彦
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-19H04490
[Presentation] Role of the intramural adipose tissue of the interatrial septum on incidence of atrial fibrillation.2020
- Author(s)
  Abe I, Miyoshi M, Ishii Y, Kira S, Oniki T, Fukuda T, Fukui A, Shinohara T, Teshima Y, Nakagawa M, Takahashi N.
- Organizer
  第84回日本循環器学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04490
[Presentation] Loss of Rho effector mDia1 attenuates pressure overload-induced hypertrophic responses and exacerbates dysfunction.2020
- Author(s)
  Abe I, Ishii Y, Miyoshi M, Kira S, Kondo H, Saito S, Teshima Y, Yufu K, Terabayashi T, Ishizaki T, Takahashi N.
- Organizer
  第84回日本循環器学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04490
[Presentation] Human epicardial adipose tissue induces rat atrial myocardial fibrosis through paracrine effects: Results of organo-culture experiments2019
- Author(s)
  Shintaro Kira, Ichitaro Abe, Yumi Ishii, Miho Miyoshi, Takahiro Oniki, Akira Fukui, Tetsuji Shinohara, Yasushi Teshima, Kunio Yufu, Tatsuo Shimada, Mikiko Nakagawa, Naohiko Takahashi
- Organizer
  第83回日本循環器学会学術集会 3.29-31, 2019 横浜
- Data Source
  KAKENHI-PROJECT-19H04490
[Presentation] 中年者の冠攣縮性狭心症と不飽和脂肪酸の関係2019
- Author(s)
  秋岡秀文, 油布邦夫, 矢野雄大, 原田泰輔, 高野正幸, 廣田慧, 米津圭佑, 安部一太郎, 齋藤聖太郎, 福井暁, 岡田憲広, 篠原徹二, 秋好久美子, 手嶋泰之, 中川幹子, 高橋尚彦
- Organizer
  日本心血管インターベンション治療学会CVIT2019
- Data Source
  KAKENHI-PROJECT-19K09398
[Presentation] Angiopoietin-like protein(Angptl) 2 secreted from epicardial adipose tissue induces atrial myocardial fibrosis2019
- Author(s)
  Shintaro Kira、 Ichitaro Abe、Yumi Ishii、Miyoshi Miho、Takahiro Oniki、Akira Fukui、Tetsuji Shinohara、 Yasushi Teshima、Kunio Yufu、Tatsuo Shimada、Mikiko Nakagawa、Motoki Arakane、Tsutomu Daa、Naohiko Takahashi
- Organizer
  第66回日本不整脈心電学会学術大会　7.24-27, 2019. 横浜
- Data Source
  KAKENHI-PROJECT-19H04490
[Presentation] Angiopoietin-like protein (Angptl) 2 secreted from epicardial adipose tissue induces atrial myocardial fibrosis2019
- Author(s)
  Shintaro Kira,Ichitaro Abe、Yasushi Teshima、Yumi Ishii、Miho Miyoshi、Takahiro Oniki、Akira Fukui、Tetsuji Shinohara、Kunio Yufu、Naohiko Takahashi
- Organizer
  European Society of Cardiology Congress 2019 8.31-9.4, 2019. パリ／フランス
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04490
[Presentation] Hyponatremia Aggravates Cardiac Susceptibility to Ischemia/Reperfusion Injury2018
- Author(s)
  Oniki T,Teshima Y,Kira S,Miyoshi M,Abe I,Ikebe Y,Yufu K,Takahashi N.
- Organizer
  第2回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-17K11578
[Presentation] Hyponatremia Aggravates Cardiac Susceptibility to Ischemia/Reperfusion Injury2018
- Author(s)
  Oniki T,Teshima Y,Kira S,Miyoshi M,Abe I,Ikebe Y,Yufu K,Takahashi N.
- Organizer
  第65回日本不整脈心電学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11578
[Presentation] 低ナトリウム血症による心筋虚血耐性の低下とその機序について2018
- Author(s)
  鬼木崇裕、手嶋泰之、髙橋尚彦
- Organizer
  第28回日本病態生理学会
- Data Source
  KAKENHI-PROJECT-17K11578
[Presentation] Glucose Fluctuations Impair Cardiac Sinus Node Function in Diabetic Animal Models2017
- Author(s)
  Ikebe Y, Teshima Y, Sonoda Y, Abe I, Yufu K, Shimada T, Miyamoto S, Takahashi N
- Organizer
  第81回日本循環器学会総会学術集会
- Place of Presentation
  ANAクラウンプラザホテル金沢（石川県・金沢市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-26462758
[Presentation] Microstructural Features of Atrial Appendage in Patients with Atrial Fibrillation2017
- Author(s)
  Sonoda Y, Teshima Y, Ikebe Y, Abe I, Yufu K, Shimada T, Miyamoto S, Takahashi N
- Organizer
  第81回日本循環器学会総会学術集会
- Place of Presentation
  ANAクラウンプラザホテル金沢（石川県・金沢市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-26462758
[Presentation] Glucose Fluctuations by Repeated Hypoglycemic Episodes Facilitate Atrial Remodeling and Atrial Fibrillation2016
- Author(s)
  Teshima Y, Saito S, Ikebe Y, Abe I, Kondo K, Yufu K, Takahashi N
- Organizer
  第80回日本循環器学会総会学術集会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26462758
[Presentation] 糖尿病における血糖変動は心房細動誘発性を亢進する2015
- Author(s)
  手嶋泰之、斉藤聖多郎、池邉有希、安部一太郎、近藤秀和、高橋尚彦
- Organizer
  第55回日本臨床化学会学術集会
- Place of Presentation
  大阪大学（大阪府、吹田市）
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26462758
[Presentation] 糖尿病患者における血糖変動と心臓自律神経機能2015
- Author(s)
  手嶋泰之、長野徳子、中川幹子、高橋尚彦
- Organizer
  第62回日本臨床検査医学会学術集会
- Place of Presentation
  長良川国際会議場（岐阜市）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-26462758
[Presentation] Glucose Fluctuations Aggravate Myocardial Ischemia/Reperfusion Injury in Type 2 Diabetic Rats2015
- Author(s)
  Saito S, Teshima Y, Abe I, Ikebe Y, Kondo K, Nishio S, Yufu K, Takahashi N
- Organizer
  第79回日本循環器学会総会学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26462758
[Presentation] Takahashi N. Hyperleptinemia exacerbates high fat diet-mediated atrial remodeling and fibrillation2014
- Author(s)
  Fukui A, Kondo H, Saito S, Nishio S, Shinohara T, Teshima Y, Saikawa T
- Organizer
  第78回日本循環器学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23592672
[Presentation] Glucose fluctuations aggravate atrial fibrillation in animal models of Type 1 and Type 2 diabetes mellitus2014
- Author(s)
  Saito S, Teshima Y, Nishio S, Kondo H, Fukui A, Nakagawa M, Saikawa T, Takahashi N
- Organizer
  第78回日本循環器学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23592672
[Presentation] Role of spleen-derived Interleukin-10 in high-fat-diet-induced inflammatory atrial fibrosis and fibrillation2014
- Author(s)
  Kondo H, Takahashi N, Saito S, Fukui A, Nishio S, Aoki K, Shinohara T, Teshima Y, Hara M, Saikawa T
- Organizer
  第78回日本循環器学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23592672
[Presentation] Role of indoxyl sulfate, a major uremic toxin, in pathogenesis of atrial fibrillation associated with chronic kidney disease2014
- Author(s)
  Aoki K, Takahashi N, Kondo H, Saito S, Nishio S, Fukui A, Shinohara T, Teshima Y, Shibata T
- Organizer
  第78回日本循環器学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23592672
[Presentation] Interleukin-10 treatment attenuates sinus node dysfunction and atrial fibrillation vulnerability caused by streptozotocin-induced hyperglycemia2014
- Author(s)
  Kondo H, Saito S, Fukui A, Nishio S, Shinohara T, Teshima Y, Takahashi N
- Organizer
  第78回日本循環器学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23592672
[Presentation] Role of H1 and H2 Receptors in Pathogenesis of Pressure Overload-mediated Atrial Fibrosis and Fibrillation.2013
- Author(s)
  Fukui A, Takahashi N, Masaki T, Konfo H, Saito S, Nishio S< Shinohara T, Teshima Y, Hara M, Saikawa T.
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23592672
[Presentation] Glucose Fluctuations Aggravate Cardiac Fibrosis Resulting in Worse Outcomes Including Atrial Fibrillation in Diabetic Rats.2013
- Author(s)
  Saito S, Teshima Y, Takahashi N, Nishio S, Kondo H, Fukui A, Hara M, Nakagawa M, Saikawa T.
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23592672
[Presentation] Glucose Fluctuations Aggravate the Vulnerability of the Heart Against Ischemia/reperfusion Injury in Diabetic Rat2013
- Author(s)
  Teshima Y, Takahashi N, Saito S, Kondo K, Fukui A, Nishio S, Nakagawa M, Saikawa T
- Organizer
  第77回日本循環器学会総会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Calcineurin plays a key role in diabetes mellitus-induced cardiac fibrosis2013
- Author(s)
  Nishio S, Teshima Y, Takahashi N, Saito S, Kondo K, Fukui A, Nakagawa M, Saikawa T
- Organizer
  第77回日本循環器学会総会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Glucose Fluctuations in Diabetic Rats Aggravate Cardiac Fibrosis Resulting in Worse Outcomes Including Atrial Fibrillation2013
- Author(s)
  Saito S, Teshima Y, Takahashi N, Kondo K, Fukui A, Nishio S, Nakagawa M, Saikawa T
- Organizer
  第77回日本循環器学会総会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Role of microRNAs in glucose fluctuations-induced vulnerability of diabetic heart to ischemia/reperfusion2013
- Author(s)
  Yasushi Teshima
- Organizer
  第77回日本循環器学会総会学術集会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] 血糖値変動が心筋虚血耐性に及ぼす影響について2012
- Author(s)
  手嶋泰之
- Organizer
  第59回日本臨床検査医学会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] 糖尿病心筋における活性酸素種増加の機序について2012
- Author(s)
  西尾諭、手嶋泰之、高橋尚彦、中川幹子、犀川哲典
- Organizer
  第52回日本臨床化学会学術集会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Role of Leptin Signaling in Pathogenesis of Atrial Fibrosis and Fibrillation.2012
- Author(s)
  Fukui A, Takahashi N, Fukunaga N, Thuc L, Kume O, Miyazaki H, Wzaki K, Shinohara T, Teshima Y, Yufu K, Hara M, Nakagawa M, Yoshimatsu H, Saikawa T.
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23592672
[Presentation] Activation of calmodulin kinase II increases reactive oxygen species in STZ-induced diabetic rat heart2012
- Author(s)
  Nishio S, Teshima Y, Takahashi N, Thuc LC, Saito S, Fukui A, Kume O, Nakagawa M, Saikawa T
- Organizer
  第76回日本循環器学会総会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] 血糖値変動が心筋虚血耐性に及ぼす影響について2012
- Author(s)
  手嶋泰之、高橋尚彦、西尾諭、江崎かおり、宮崎寛子、中川幹子、犀川哲典
- Organizer
  第58回日本臨床検査医学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Repeated hypoglycemia increases the vulnerability of diabetic heart against ischemia/reperfusion2012
- Author(s)
  Thuc LC, Teshima Y, Nishio S, Fukui A, Kume O, Nakagawa M, Takahashi N, Saikawa T
- Organizer
  第76回日本循環器学会総会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Glucose Fluctuations Aggravate the Vulnerability of the Heart Against Ischemia/reperfusion Injury in Diabetic Rat2012
- Author(s)
  Teshima Y, Takahashi N, Saito S, Kondo K, Fukui A, Nishio S, Nakagawa M, Saikawa T
- Organizer
  9th IDF-WPR Congress 2012
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Glucose fluctuations in diabetic rats aggravate cardiac fibrosis resulting in worse outcomes including atrial fibrillation2012
- Author(s)
  Saito S, Teshima Y, Takahashi N, Fukui A, Kondo K, Nishio S, Nakagawa M, Saikawa T
- Organizer
  第29回国際心臓研究学会(ISHR)日本部会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] 糖尿病心臓におけるカルモジュリンキナーゼを介した活性酸素種増加の機序について2012
- Author(s)
  西尾諭、手嶋泰之、高橋尚彦、中川幹子、犀川哲典
- Organizer
  第22回日本病態生理学会
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Glucose Fluctuations Aggravate the Vulnerability of the Heart Against Ischemia/reperfusion Injury in Diabetic Rat2012
- Author(s)
  Yasushi Teshima
- Organizer
  American Heart Association Scientific Sessions 2012
- Place of Presentation
  Los Angels
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Calmodulin kinase II induces mitochondrial dysfunction by increasing ROS production in STZ-induced diabetic rat heart2012
- Author(s)
  Saikawa T, Nishio S, Takahashi N, Thuc LC, Saito S, Fukui A, Kume O, Yufu K, Hara M, Nakagawa M, Teshima Y
- Organizer
  ESC Congress 2012
- Place of Presentation
  Munich, Germany
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Glucose Fluctuations Aggravate the Vulnerability of Diabetic Heart Against Ischemia/reperfusion mediated via microRNAs modulation2012
- Author(s)
  Teshima Y, Takahashi N, Thuc LC, Nishio S, Saito S, Fukui A, Kume O, Nakagawa M Saikawa T
- Organizer
  American Heart Association Scientific Sessions 2012
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Glucose Fluctuations Aggravate the Vulnerability of Diabetic Heart Against Ischemia/reperfusion mediated via microRNAs modulation2012
- Author(s)
  Yasushi Teshima
- Organizer
  9th International Diabetes Federation -Western Pacific Region Congress
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Activation of calmodulin kinase II by increased Na^+-H^+ exchange : as a mechanism of high glucose-induced reactive oxygen species production in cardiomyocytes2011
- Author(s)
  Satoru Nishio, Yasushi Teshima, Tetsunori Saikawa
- Organizer
  第75回日本循環器学会総会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590209
[Presentation] Role of Leptin Signaling in Pathogenesis of Atrial Fibrosis and Fibrillation2011
- Author(s)
  Fukui A, Takahashi N, Teshima Y, Yufu K, Nakagawa M, Saikawa T, Kume O, Wakisaka O, Shinohara T, Hara M, Yoshimatsu H.
- Organizer
  Annual meeting of American Heart Associatoin
- Place of Presentation
  orlando
- Data Source
  KAKENHI-PROJECT-23592672
[Presentation] 高グルコースによる心筋における活性酸素増加のメカニズムについて2010
- Author(s)
  西尾諭、手嶋泰之, 他
- Organizer
  第57回日本臨床検査医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590209

1. TAKAHASHI NAOHIKO (30263239)

# of Collaborated Projects: 3 results

# of Collaborated Products: 36 results
2. SAIKAWA Tetsunori (60145365)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
3. HAGIWARA Satoshi (50527661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. NOGUCHI Takayuki (90156183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. Akioka Hidefumi (80795914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 安部一太郎 (00747595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. 宮本伸二 (70253797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 福井暁 (70631381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. 石井悠海 (20835607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Saito Shotaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. Nishio Satoru

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. TERABAYASHI Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 石崎敏理

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 花田克浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 篠原徹二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Teshima Yasushi 手嶋 泰之

TESHIMA Yasushi 手嶋 泰之

Research Projects

Research Products

Co-Researchers

心不全患者における無自覚低血糖の発生実態の解明と新規心不全治療戦略としての応用Principal Investigator

Principal Investigator

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Review Section

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Relationship between coronary spastic angina and glycemic fluctuation

Principal Investigator

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Review Section

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Mechanisms of epicardial adipose tissue to cause atrial myocardial fibrosis and screening of compounds to suppress them

Principal Investigator

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Review Section

Research Institution

Effects of hyponatremia on cardiac susceptibility to ischemia/reperfusion injuryPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

A new strategy targeting microRNAs for cardiac protection against ischemia/reperfusion injuryPrincipal Investigator

Principal Investigator

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Research Institution

Novel Strategy to prevent ischemia/reperfusion injury that overcomes disadvantages of antioxidant agents

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the effect and mechanism of repeated hypoglycemiaon cardiomyocytes in an animal model of diabetes mellitusPrincipal Investigator

Principal Investigator

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Research Category

Research Field

Research Institution

[Journal Article] Detection of fibrotic remodeling of epicardial adipose tissue in patients with atrial fibrillation: Imaging approach based on histological observation2021

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[Journal Article] Role of angiopoietin-like protein 2 in atrial fibrosis induced by human epicardial adipose tissue: Analysis using an organo-culture system2020

Author(s)

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DOI

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[Journal Article] A traditional herbal medicine rikkunshito prevents angiotensin II-Induced atrial fibrosis and fibrillation2020

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[Journal Article] Impact of Age on Gender Differences in the Acute Myocardial Infarction Onset–Weather Association ― Oita AMI Registry ―2020

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[Journal Article] Disruption of actin dynamics regulated by Rho effector mDia1 attenuates pressure overload-induced cardiac hypertrophic responses and exacerbates dysfunction2020

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Data Source

[Journal Article] 冠攣縮性狭心症と多価不飽和脂肪酸の関係における性差2020

Author(s)

Journal Title

NAID

Teshima Yasushi 手嶋泰之

TESHIMA Yasushi 手嶋泰之

[Journal Article] Impact of Age on Gender Differences in the Acute Myocardial Infarction Onset–Weather Association　― Oita AMI Registry ―2020