HAGIWARA Satoshi 萩原聡

Researcher Number	50527661
Affiliation (based on the past Project Information) *help	2009 – 2015: Oita University, 医学部, 講師
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies Except Principal Investigator Emergency medicine / Anesthesiology/Resuscitation studies / Digestive surgery
Keywords	Principal Investigator 炎症 / 静脈栄養 / エンドトキシン / 敗血症 / オートファジー Except Principal Investigator ビタミンE / 酸化ストレス / 感染症 / 血液浄化療法 / 臓器傷害 … More / 敗血症 / ビタミンＥ / vitamin E / spnal cord injury / ETS-GS / 脊髄損傷 / 虚血再灌流障害 / メタボリック症候群 / 心房細動 / 胃癌 / アポトーシス / 腹膜播種 / 腫瘍増殖 / オートファジー / 抗酸化剤 / 腫瘍学 / 小腸大腸肛門外科学 Less

Development of Novel Therapeutic Strategy for Spinal Cord Injury by New Vitamin E derivative, ETS-GS
- Principal Investigator
  
  Uchino Tomoko
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Oita University
Development of new therapeutic strategies for severe sepsis by blood purification therapy targeting at control of oxidative stress.
- Principal Investigator
  
  HIDAKA SEIGO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Oita University
An establishment of new tumor dormancy therapy based on regulation of radical scavenger
- Principal Investigator
  
  INOMATA MASAFUMI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Oita University
Novel Strategy to prevent ischemia/reperfusion injury that overcomes disadvantages of antioxidant agents
- Principal Investigator
  
  TAKAHASHI NAOHIKO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Oita University
The role and the control method of autophagy at systemic inflammationPrincipal Investigator
- Principal Investigator
  
  HAGIWARA Satoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Oita University

All 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Bolus injection of newly synthesized vitamin E derivative ETS-GS for the treatment of acute severe ulcerative colitis in a mouse model. New vitamin E derivative for acute severe UC.2013
- Author(s)
  Hiratsuka T, Inomata M, Hagiwara S, Kono Y, Shiraishi N, Noguchi T, Kitano S.
- Journal Title
  
  Int J colorectal Dis.
  
  Volume: 28(3) Issue: 3 Pages: 305-11
- DOI
  10.1007/s00384-012-1502-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591967, KAKENHI-PROJECT-24791385, KAKENHI-PROJECT-25462030
[Journal Article] Antiproliferative effects of a new α-lipoic acid derivative, DHL-HisZnNa, in HT29 human colon cancer cells in vitro2012
- Author(s)
  Kono Y,　Inomata M, Hagiwara S, Hiratsuka T, Suzuki K, Koga H, Shiraishi N, Noguchi T, Kitano S
- Journal Title
  
  Expert Opinion On Therapeutic Targets
  
  Volume: 16(S1) Issue: sup1 Pages: S103-S109
- DOI
  10.1517/14728222.2011.640320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591967, KAKENHI-PROJECT-24791385
[Journal Article] A newly synthetic vitamin E derivative, E-Ant-S-GS, attenuates lung injury caused by cecal ligation and puncrure-unduced sepsis in rats2012
- Author(s)
  Kono Y, Inomata M, Hagiwara S, Shiraishi N, Noguchi T, Kitano S
- Journal Title
  
  Surgery
  
  Volume: 151(3) Issue: 3 Pages: 420-426
- DOI
  10.1016/j.surg.2011.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591967, KAKENHI-PROJECT-24791385
[Journal Article] Establishment of a model of atrial fibrillation associated with chronic kidney disease in rats and the role of oxidative stress.2012
- Author(s)
  Fukunaga N, Takahashi N, Hagiwara S, Kume O, Fukui A, Teshima Y, Shinohara T, Nawata T, Hara M, Noguchi T, Saikawa T.
- Journal Title
  
  Heart Rhythm
  
  Volume: 12 Issue: 12 Pages: 2023-31
- DOI
  10.1016/j.hrthm.2012.08.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592672
[Journal Article] Stimulation of autophagy in the liver by lipopolysaccharide-induced systemic inflammation in a rat model of diabetes mellitus2010
- Author(s)
  Hagiwara S, Iwasaka H, Koga H, Hasegawa A, Kudo K, Kusaka J, Oyama Y, Noguchi T
- Journal Title
  
  Biomed Res
- NAID
  130004903804
- Data Source
  KAKENHI-PROJECT-21591977
[Journal Article] Infusion of a Glucose Solution Reduces Autophagy in the Liver after LPS-induced Systemic Inflammation
- Author(s)
  Hagiwara S, Iwasaka H, Hasegawa A, Kudo K, Kusaka J, Oyama Y, Noguchi T
- Journal Title
  
  Inflammation
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21591977
[Presentation] デキストラン硫酸ナトリウム大腸炎に対する光線照射の治療効果―炎症性腸疾患に対する光線を用いた新規治療法の開発―2012
- Author(s)
  平塚孝宏、井聖子、赤木智徳、當寺ヶ盛学、柴田智隆、白下英史、衛藤剛、猪股雅史、小山淑正、萩原聡、野口隆之、白石憲男、北野正剛
- Organizer
  第3回癌・炎症とαリポ酸研究会プログラム
- Place of Presentation
  大分県由布市
- Data Source
  KAKENHI-PROJECT-23591967
[Presentation] The alpha-lipoic acid derivative, sodium zinc dihydrolipoylhistidinate (DHLHZn),reduces chemotherapy-induced alopecia in a rat model2011
- Author(s)
  Masafumi Inomata, Yohei kono, Takahiro Hiratsuka, Fumitaka Yoshizumi, Norio Shiraishi, Satoshi Hagiwara, Tsuyoshi Noguchi, Seigo Kitano
- Organizer
  International Surgical Week 2011
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591967
[Presentation] 新規抗酸化剤αリポ酸誘導体を用いた癌治療法の開発―新たな細胞死Autophagyへの誘導―2011
- Author(s)
  平塚孝宏、河野洋平、　杉田諭、草野徹、　　　中嶋健太郎、赤木智徳、萩原聡、衛藤剛、　　　安田一弘、猪股雅史、　野口剛、白石憲男、　　野口隆之、北野正剛
- Organizer
  第16回癌と遺伝子大分外科フォーラム
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-23591967
[Presentation] αリポ酸誘導体（DHLHZn）の癌幹細胞様細胞を介した抗腫瘍効果の検討2011
- Author(s)
  赤木智徳, 三森功士, 石橋正久, 澤田元太, 高橋佑典, 古後龍之介, 西田尚弘, 岩谷岳, 主藤朝也, 田中文明, 柴田浩平, 猪股雅史, 白石憲男, 北野正剛, 萩原聡, 野口隆之, 森正樹
- Organizer
  第2回癌・炎症とαリポ酸研究会(招待講演)
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-23591967
[Presentation] The alpha-lipoic acid derivative, sodium zinc dihydrolipoylhistidinate (DHLHZn), reduces chemotherapy- induced alopecia in a rat model2011
- Author(s)
  Masafumi Inomata, Yohei kono, Takahiro Hiratsuka, Fumitaka Yoshizumi, Norio Shiraishi, Satoshi Hagiwara, Tsuyoshi Noguchi, Seigo Kitano
- Organizer
  International Surgical Week 2011
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-08-28
- Data Source
  KAKENHI-PROJECT-23591967
[Presentation] 抗癌剤誘発脱毛に対するαリポ酸誘導体の軽減効果2011
- Author(s)
  河野洋平, 吉住文孝, 猪股雅史, 北野正剛, 萩原聡, 野口隆之
- Organizer
  第2回癌・炎症とαリポ酸研究会(招待講演)
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-23591967
[Presentation] 重症患者管理における臓器保護戦略2010
- Author(s)
  萩原聡
- Organizer
  関東甲信越
- Place of Presentation
  集中治療地方会
- Data Source
  KAKENHI-PROJECT-21591977
[Presentation] 敗血症モデルでの病態形成におけるオートファジーの関与について2009
- Author(s)
  今冨良太、岩坂日出男、長谷川輝、萩原聡、野口隆之
- Organizer
  第15回日本エンドトキシン研究会
- Data Source
  KAKENHI-PROJECT-21591977

1. NOGUCHI Takayuki (90156183)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
2. INOMATA MASAFUMI (60315330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. KITANO Seigou (90169871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. MORIYAMA Masatsugu (90239707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ETOH Tsuyoshi (00404369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. HIRATSUKA Takahiro (20600886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. TAKAHASHI NAOHIKO (30263239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. TESHIMA Yasushi (10457608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. SAIKAWA Tetsunori (60145365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. Uchino Tomoko (90404368)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Oyama Yoshimasa (40468012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HIDAKA SEIGO (00404385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KITANO Takaaki (20211196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 緒方一美 (70596048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HAGIWARA Satoshi 萩原 聡

Research Projects

Research Products

Co-Researchers

Development of Novel Therapeutic Strategy for Spinal Cord Injury by New Vitamin E derivative, ETS-GS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new therapeutic strategies for severe sepsis by blood purification therapy targeting at control of oxidative stress.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An establishment of new tumor dormancy therapy based on regulation of radical scavenger

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel Strategy to prevent ischemia/reperfusion injury that overcomes disadvantages of antioxidant agents

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role and the control method of autophagy at systemic inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Bolus injection of newly synthesized vitamin E derivative ETS-GS for the treatment of acute severe ulcerative colitis in a mouse model. New vitamin E derivative for acute severe UC.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antiproliferative effects of a new α-lipoic acid derivative, DHL-HisZnNa, in HT29 human colon cancer cells in vitro2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A newly synthetic vitamin E derivative, E-Ant-S-GS, attenuates lung injury caused by cecal ligation and puncrure-unduced sepsis in rats2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of a model of atrial fibrillation associated with chronic kidney disease in rats and the role of oxidative stress.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stimulation of autophagy in the liver by lipopolysaccharide-induced systemic inflammation in a rat model of diabetes mellitus2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Infusion of a Glucose Solution Reduces Autophagy in the Liver after LPS-induced Systemic Inflammation

Author(s)

Journal Title

Data Source

[Presentation] デキストラン硫酸ナトリウム大腸炎に対する光線照射の治療効果―炎症性腸疾患に対する光線を用いた新規治療法の開発―2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] The alpha-lipoic acid derivative, sodium zinc dihydrolipoylhistidinate (DHLHZn),reduces chemotherapy-induced alopecia in a rat model2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 新規抗酸化剤αリポ酸誘導体を用いた癌治療法の開発―新たな細胞死Autophagyへの誘導―2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] αリポ酸誘導体（DHLHZn）の癌幹細胞様細胞を介した抗腫瘍効果の検討2011

Author(s)

HAGIWARA Satoshi 萩原聡