SAKAI KATSUYA 酒井克也

… Alternative Names

Sakai Katsuya 酒井克也

SAKAI Katsuya 酒井克也

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Researcher Number	10523318
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, がん進展制御研究所, 准教授
Affiliation (based on the past Project Information) *help	2025: 金沢大学, がん進展制御研究所, 准教授 2020 – 2022: 金沢大学, がん進展制御研究所, 准教授 2016 – 2018: 金沢大学, がん進展制御研究所, 助教 2014: 金沢大学, がん進展制御研究所, 助教 2011 – 2012: 金沢大学, がん進展制御研究所, 助教 2010: 金沢大学, がん研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / General pharmacology / General anatomy (including Histology/Embryology) Except Principal Investigator Functional biochemistry / Tumor biology / General medical chemistry
Keywords	Principal Investigator ペプチド / 環状ペプチド / 受容体 / 増殖因子 / 高機能ペプチド / 抗体改変 / AFM / lasso-graft / NASH / タンパク質エンジニアリング … More / サイトカイン・増殖因子 / HGF-MET / HS-AFM / タンパク質工学 / mRNA display / 受容体リガンド / 人工リガンド / リガンド / 形態形成 / 分化 / Tetraploid / がん化 / 組織幹細胞 / 再生医学 / 浸潤 … More Except Principal Investigator HGF / 細胞増殖因子 / チロシンキナーゼ / シグナル伝達 / Met / 受容体 / 特殊環状ペプチド / MET / ペプチド / 増殖因子 / 増殖因子受容体 / サイトカイン / MMP / PRC / エピジェネティクス / がん細胞 / 環状ペプチド / 人工アゴニスト / 浸潤 / 薬剤耐性 / 転移 / 形態形成 / 肝再生 / ノックアウトマウス / 再生医学 / 組織再生 Less

変異成長ホルモン受容体の機能検証と人工リガンドによる救済Principal Investigator
- Principal Investigator
  
  酒井克也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Kanazawa University
Mechanism and manipulation of growth factor receptors by bioactive peptides and AFMPrincipal Investigator
- Principal Investigator
  
  Sakai Katsuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Kanazawa University
Establishment of artificial ligands technology for peptide hormone receptors with functional mutationsPrincipal Investigator
- Principal Investigator
  
  Sakai Kastuya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kanazawa University
Signal characteristics of heatero-receptor coupling and generation of artificial ligand
- Principal Investigator
  
  Matsumoto Kunio
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Kanazawa University
Mechanisms for malignant tumor progression based on acquisition of 3-D invasiveness and regulation of epithelial morphogenesis
- Principal Investigator
  
  MATSUMOTO Kunio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Research of dynamic differentiation and morphogenesis in 3-D epithelial tubulogenesisPrincipal Investigator
- Principal Investigator
  
  SAKAI Katsuya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kanazawa University
Research on tissue regeneration regulated by Met/HGF receptor ON-OFF regulation
- Principal Investigator
  
  MATSUMOTO Kunio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa University

[Book] ものづくり技術からみる再生医療ー細胞研究・創薬・治療ー2018
- Author(s)
  酒井克也、松本　邦夫
- Total Pages
  282
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-16K08544
[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術2017
- Author(s)
  酒井克也ら　共著
- Total Pages
  557
- Publisher
  技術情報協会
- ISBN
- Data Source
  KAKENHI-PROJECT-16K08544
[Book] 医療・診断をささえるペプチド科学2017
- Author(s)
  松本邦夫　菅裕明　酒井克也ら　共著
- Total Pages
  315
- Publisher
  シーエムシー出版
- ISBN
  9784781312675
- Data Source
  KAKENHI-PROJECT-16K08544
[Book] Hepatocyte growth factor. In “Reference Module in BiomedicalSciences”2015
- Author(s)
  Sakai K, Nakamura T, Kinoshita T, Matsumoto K.
- Publisher
  Elsevier Inc
- Data Source
  KAKENHI-PROJECT-24300329
[Book] "MspとMsp受容体"サイトカイン・増殖因子キーワード事典2015
- Author(s)
  酒井克也、松本邦夫
- Total Pages
  420
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15K14473
[Book] “MspとMsp受容体（Ron）”「サイトカイン・増殖因子キーワード事典」2015
- Author(s)
  酒井克也、松本邦夫
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24300329
[Book] “Met/HGF受容体の制御”、「細胞膜受容体」（生体の科学）2013
- Author(s)
  酒井克也、松本邦夫
- Total Pages
  522
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-24300329
[Book] “HGF-Met系を標的とするがん創薬の意義と開発”、「次世代がん戦略研究update がん基盤生物学－革新的シーズ育成に向けて－」2013
- Author(s)
  足立恵理、酒井克也、木下富誉、松本邦夫
- Total Pages
  336
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-24300329
[Book] InTech2011
- Author(s)
  Sakai K, Nakamura T, Suzuki Y, Matsumoto K
- Publisher
  Significance, Mechanisms, and Progress of Anticancer Drugs Targeting HGF-Met
- URL
  http://www.intechopen.com/books/advances-in-cancer-therapy/significance-mechanisms-and-progress-ofanticancerdrugs-targeting-hgf-met
- Data Source
  KAKENHI-PROJECT-23790221
[Book] In"Cancer Treatment"(Significance, mechanisms, and progress of anticancer drugs targeting HGF-Met)2011
- Author(s)
  Sakai K, Nakamura T, Suzuki Y, Matsumoto K
- Publisher
  InTech Open Access Publisher, in press
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration2022
- Author(s)
  Hino Naoya、Matsuda Kimiya、Jikko Yuya、Maryu Gembu、Sakai Katsuya、Imamura Ryu、Tsukiji Shinya、Aoki Kazuhiro、Terai Kenta、Hirashima Tsuyoshi、Trepat Xavier、Matsuda Michiyuki
- Journal Title
  
  Developmental Cell
  
  Volume: 57 Issue: 19 Pages: 2290-2304
- DOI
  10.1016/j.devcel.2022.09.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00993, KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-23K21377, KAKENHI-PROJECT-23K23888, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05798, KAKENHI-PLANNED-20H05898
[Journal Article] Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions2022
- Author(s)
  Sakai Katsuya、Sugano-Nakamura Nozomi、Mihara Emiko、Rojas-Chaverra Nichole Marcela、Watanabe Sayako、Sato Hiroki、Imamura Ryu、Voon Dominic Chih-Cheng、Sakai Itsuki、Yamasaki Chihiro、Tateno Chise、Shibata Mikihiro、Suga Hiroaki、Takagi Junichi、Matsumoto Kunio
- Journal Title
  
  Nature Biomedical Engineering
  
  Volume: 7 Issue: 2 Pages: 164-176
- DOI
  10.1038/s41551-022-00955-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-21K15482, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-21H01771, KAKENHI-PROJECT-20K06553, KAKENHI-PUBLICLY-21H00247
[Journal Article] De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist2021
- Author(s)
  Komatsu Yamato、Terasaka Naohiro、Sakai Katsuya、Mihara Emiko、Wakabayashi Risa、Matsumoto Kunio、Hilvert Donald、Takagi Junichi、Suga Hiroaki
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 11 Pages: 103302-103302
- DOI
  10.1016/j.isci.2021.103302
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-21K18250
[Journal Article] Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins2021
- Author(s)
  Mihara E, Watanabe S, Bashiruddin N, Nakamura N, Matoba K, Maini R, Yin Y, Sakai K, Arimori T, Matsumoto K, Suga H, and Takagi J.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1543-1543
- DOI
  10.1038/s41467-021-21875-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-18H02389, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-20K20581
[Journal Article] Macrocyclic Peptide-Conjugated Tip for Fast and Selective Molecular Recognition Imaging by High-Speed Atomic Force Microscopy2021
- Author(s)
  L. Pupplin, D. Kanayama, N. Terasaka, K. Sakai, N. Kodera, K. Umeda, A. Sumino, M. Arin, W. Wei, H. Tanaka, T. Fukuma, H. Suga, K. Matsumoto, M. Shibata
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 13(46) Issue: 46 Pages: 54817-54829
- DOI
  10.1021/acsami.1c17708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19422, KAKENHI-PROJECT-20K21122, KAKENHI-PUBLICLY-21H00247, KAKENHI-PLANNED-21H05251, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-21H01771, KAKENHI-PROJECT-17H05058, KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-21K04849, KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-21H04127
[Journal Article] Dimer interface in natural variant NK1 is dispensable for HGF-dependent Met receptor activation.2021
- Author(s)
  Yumiko Tahira, Katsuya Sakai, Hiroki Sato, Ryu Imamura, and Kunio Matsumoto
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 22 Issue: 17 Pages: 9240-9240
- DOI
  10.3390/ijms22179240
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-21K15482
[Journal Article] The constitutive high affinity Met binding site in the kringle domain is dispensable for the signaling activity of hepatocyte growth factor.2020
- Author(s)
  Umitsu M, Sakai K, Tamura-Kawakami K, Matsumoto K, Takagi J.
- Journal Title
  
  JOURNAL OF BIOCHEMISTRY
  
  Volume: - Issue: 6 Pages: 577-586
- DOI
  10.1093/jb/mvaa006
- NAID
  40022260383
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-18K19298, KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-19H03499
[Journal Article] Proteasomal degradation of polycomb-group protein CBX6 confers MMP-2 expression essential for mesothelioma invasion2020
- Author(s)
  Sakai Katsuya、Nishiuchi Takumi、Tange Shoichiro、Suzuki Yoshinori、Yano Seiji、Terashima Minoru、Suzuki Takeshi、Matsumoto Kunio
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 16678-16678
- DOI
  10.1038/s41598-020-72448-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07346, KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-18K06057
[Journal Article] Cyclic Peptide-Based Biologics Regulating HGF-MET.2020
- Author(s)
  Hiroki Sato, Ryu Imamura, Hiroaki Suga, Kunio Matsumoto, Katsuya Sakai
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 21 Issue: 21 Pages: 7977-7977
- DOI
  10.3390/ijms21217977
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-18K15306
[Journal Article] Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor2019
- Author(s)
  Katsuya Sakai, Toby Passioura, Hiroki Sato, Kenichiro Ito, Hiroki Furuhashi, Masataka Umitsu, Junichi Takagi, Yukinari Kato, Hidefumi Mukai, Shota Warashina, Maki Zouda, Yasuyoshi Watanabe, Seiji Yano, Mikihiro Shibata, Hiroaki Suga, and Kunio Matsumoto
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08544
[Journal Article] Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist2018
- Author(s)
  Miao Wenyu、Sakai Katsuya、Ozawa Naoya、Nishiuchi Takumi、Suzuki Yoshinori、Ito Kenichiro、Morioka Tomomi、Umitsu Masataka、Takagi Junichi、Suga Hiroaki、Matsumoto Kunio
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 16492-16492
- DOI
  10.1038/s41598-018-34835-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19298, KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-16K08544, KAKENHI-PROJECT-16J05654
[Journal Article] MET Activation by a Macrocyclic Peptide Agonist that Couples to Biological Responses Differently from HGF in a Context-Dependent Manner.2018
- Author(s)
  Miao W, Sakai K, Imamura R, Ito K, Suga H, Sakuma T, Yamamoto T, Matsumoto K.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19 Issue: 10 Pages: 3141-3141
- DOI
  10.3390/ijms19103141
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26220204, KAKENHI-PROJECT-16K08544
[Journal Article] Cell-autonomous changes in Met receptor expression regulate the growth and metastatic characteristics in malignant melanoma.2016
- Author(s)
  Adachi E, Sakai K, Nishiuchi T, Imamura R, Sato H, Matsumoto K.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 43 Pages: 70779-70793
- DOI
  10.18632/oncotarget.12221
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14473
[Journal Article] Non-small cell lung cancer cells acquire resistance to the ALK inhibitor alectinib by activating alternative receptor tyrosine kinases.2016
- Author(s)
  Isozaki H, Ichihara E, Takigawa N, Ohashi K, Ochi N, Yasugi M, Ninomiya T, Yamane H, Hotta K, Sakai K, Matsumoto K, Hosokawa S, Bessho A, Sendo T, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Research
  
  Volume: 76 Issue: 6 Pages: 1506-1516
- DOI
  10.1158/0008-5472.can-15-1010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14473
[Journal Article] Probing conformational and functional states of human hepatocyte growth factor by a panel of monoclonal antibodies.2016
- Author(s)
  Umitsu M, Sakai K, Ogasawara S, Kaneko M, Asaki R, Tamura-Kawakami K, Kato Y, Matsumoto K, Takagi J.
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 33149-33149
- DOI
  10.1038/srep33149
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111006, KAKENHI-PROJECT-15K14473
[Journal Article] Hepatocyte growth factor and Met in drug discovery2015
- Author(s)
  Sakai H, Aoki S, Matsumoto K
- Journal Title
  
  J. Biochem.
  
  Volume: 157 Issue: 5 Pages: 271-284
- DOI
  10.1093/jb/mvv027
- NAID
  120005647661
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460145, KAKENHI-PROJECT-15K14473
[Journal Article] Artificial human Met agonists based on macrocycle scaffolds2015
- Author(s)
  Ito K, Sakai K, Suzuki Y, Ozawa N, Hatta T, Natsume T, Matsumoto K, Suga H.
- Journal Title
  
  Nature Communications
  
  Volume: 6 Issue: 1 Pages: 6373-6373
- DOI
  10.1038/ncomms7373
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-15K14473, KAKENHI-PROJECT-26220204
[Journal Article] Hepatocyte growth factor and Met in drug discovery.2015
- Author(s)
  Sakai K, Aoki S, Matsumoto K.
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 印刷中
- NAID
  120005647661
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300329
[Journal Article] HGF-Met pathway in regeneration and drug discovery.2014
- Author(s)
  Matsumoto K, Funakoshi H, Takahashi H, Sakai K.
- Journal Title
  
  Biomedicines
  
  Volume: 2 Issue: 4 Pages: 275-300
- DOI
  10.3390/biomedicines2040275
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300329
[Journal Article] Inhibition of transforming growth factor-β signaling potentiates tumor cell invasion into collagen matrix induced by fibroblast-derived hepatocyte growth factor.2014
- Author(s)
  Oyanagi, J., Kojima, N., Sato, H., Higashi, S., Kikuchi, K., Sakai, K., Matsumoto, K., Miyazaki, K.
- Journal Title
  
  Exp Cell Res.
  
  Volume: 印刷中 Issue: 2 Pages: 267-279
- DOI
  10.1016/j.yexcr.2014.04.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-23112517, KAKENHI-PROJECT-23300351, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-25440033, KAKENHI-PROJECT-26430119
[Journal Article] Inhibitor of transforming growth factor-β potentiates fibroblast-dependent tumor cell invasion into collagen matrix by increasing secretion of hepatocyte growth factor from fibroblasts.2014
- Author(s)
  Oyanagi J, Kojima N, Higashi S, Kikuchi K, Sakai K, Matsumoto K, Miyazaki K.
- Journal Title
  
  Exp Cell Res
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300329
[Journal Article] α-Lipoic acid-induced inhibition of proliferation and met phosphorylation in human non-small cell lung cancer cells2013
- Author(s)
  Michikoshi H, Nakamura T, Sakai K, (他4名)
- Journal Title
  
  Cancer Lett
  
  Volume: 335(2) Issue: 2 Pages: 472-478
- DOI
  10.1016/j.canlet.2013.03.008
- NAID
  120005254051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790221, KAKENHI-PROJECT-24300329
[Journal Article] Met/HGF receptor activation is regulated by juxtamembrane Ser985 phosphorylation in hepatocytes2013
- Author(s)
  Mizuho Nakayama
- Journal Title
  
  Cytokine
  
  Volume: XXX Issue: 3 Pages: 446-452
- DOI
  10.1016/j.cyto.2013.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790221, KAKENHI-PROJECT-24300329
[Journal Article] Suppression of fibrogenic gene expression and liver fibrosis using a synthetic prostacyclin agonist.2013
- Author(s)
  Xu Q, Sakai K, Nakayama M, Suzuki Y, Tambo C, Sakai Y, Matsumoto K.
- Journal Title
  
  Biomed Res
  
  Volume: 34 Pages: 241-250
- NAID
  130004903851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300329
[Journal Article] Lower gefitinib dose led to earlier resistance acquisition before emergence of T790M mutation in epidermal growth factor receptor-mutated lung cancer model.2013
- Author(s)
  Hayakawa H, Ichihara E, Ohashi K, Ninomiya T, Yasugi M, Takata S, Sakai K, Matsumoto K, Takigawa N, Tanimoto M, Kiura K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Issue: 11 Pages: 1440-1446
- DOI
  10.1111/cas.12284
- NAID
  120005468272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24300329
[Journal Article] Beneficial effect of a synthetic prostacyclin agonist, ONO-1301, in rat autoimmune myocarditis model2013
- Author(s)
  Y. Hirata, H. Kurobe, E. Uematsu, S. Yagi, T. Soeki, H. Yamada, D. Fukuda, M. Shimabukuro, M. Nakayama, K. Matsumoto, Y. Sakai, T. Kitagawa, M. Sata
- Journal Title
  
  Eur. J. Pharmacol.
  
  Volume: 699 Issue: 1-3 Pages: 81-87
- DOI
  10.1016/j.ejphar.2012.11.045
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21117007, KAKENHI-PROJECT-22390159, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390331, KAKENHI-PROJECT-24659392, KAKENHI-PROJECT-25293184, KAKENHI-PROJECT-25670390
[Journal Article] Oral administration of a novel long-acting prostacyclin agonist with thromboxane synthase inhibitory activity for pulmonary arterial hypertension.2013
- Author(s)
  Nakamura A, Nagaya N, Obata H, Sakai K, Sakai Y, Yoshikawa M, Hamada K, Matsumoto K, Kimura H.
- Journal Title
  
  Circulation J
  
  Volume: 77 Pages: 2127-2133
- NAID
  10031178685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300329
[Journal Article] A novel long-acting prostacyclin agonist (ONO-1301) with an angiogenic effect: promoting synthesis of hepatocyte growth factor and increasing cyclic AMP concentration via IP receptor signaling.2013
- Author(s)
  Uchida T, Hazekawa M, Yoshida M, Matsumoto K, Sakai Y.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 123 Pages: 392-401
- NAID
  130003382611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300329
[Journal Article] Suppression of acute hepatic injury by a synthetic prostacyclin agonist through hepatocyte growth factor expression2012
- Author(s)
  Qing Xu
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 302 Issue: 4 Pages: 420-429
- DOI
  10.1152/ajpgi.00216.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790221, KAKENHI-PROJECT-23790327
[Journal Article] 3-D collagen-dependent cell surface expression of MT1-MMP and MMP-2 activation regardless of integrin β1 function and matrix stiffness2011
- Author(s)
  Sakai K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 412 Pages: 98-103
- NAID
  120003308573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790221
[Journal Article] Hepatocyte growth factor twenty years on : much more than a growth factor.2011
- Author(s)
  Nakamura T, Sakai K, Nakamura T, Matsumoto K.
- Journal Title
  
  J.Gastroenterol. Hepatol. 26
  
  Pages: 188-202
- NAID
  120003141437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Hepatocyte growth factor twenty years on: much more than a growth factor.2011
- Author(s)
  Nakamura T, Sakai K, Nakamura T, Matsumoto K.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 26 Pages: 188-202
- NAID
  120003141437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Pleural mesothelioma instigates tumor associated fibroblasts to promote prog-ression via malignant cytokine network2011
- Author(s)
  Li Q, Wang W, Yamada T, Matsumoto K, Bando Y, Uehara H, Nishioka Y, Sone S, Iwakiri S, Itoi K, Utsugi T, Yano S.
- Journal Title
  
  Am J Pathol
  
  Volume: 179 Issue: 3 Pages: 1483-93
- DOI
  10.1016/j.ajpath.2011.05.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23659434, KAKENHI-PROJECT-23790221, KAKENHI-PROJECT-23790902
[Journal Article] HGF-Antagonists : Structure, Activities, and Anti-cancer Approach.2011
- Author(s)
  Sakai K, Nakamura T, Kinoshita T, Nakamura T, Matsumoto K.
- Journal Title
  
  Current Signal Transduction Therapy 6
  
  Pages: 191-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] HGF-antagonists : structure, activities, and anti-cancer approach.2011
- Author(s)
  Sakai K, Nakamura T, Kinoshita T, Nakamura T, Matsumoto, K.
- Journal Title
  
  Current Signal Transduction Therapy
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] HGF-Antagonists: Structure, Activities, and Anti-cancer Approach2011
- Author(s)
  Sakai K, Nakamura T, Kinoshita T, Nakamura T, Matsumoto K
- Journal Title
  
  Current Signal Transduction Therapy
  
  Volume: 6 Pages: 191-199
- URL
  http://dx.doi.org/10.2174/157436211795659964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790221
[Journal Article] 3-D collagen-dependent cell surface expression of MT1-MMP and MMP-2 activation regardless of integrin β1 function and matrix stiffness2011
- Author(s)
  Sakai K, Nakamura T, Suzuki Y, ImizuT, and Matsumoto K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412 Issue: 1 Pages: 98-103
- DOI
  10.1016/j.bbrc.2011.07.050
- NAID
  120003308573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790221, KAKENHI-PROJECT-23790327
[Journal Article] p27 Nuclear localization and growth arrest caused by perlecan knockdown in human endothelial cells.2010
- Author(s)
  Sakai K Oka K, Matsumoto K, Nakamura T.
- Journal Title
  
  Biochcm.Biophys.Res.Commun.
  
  Volume: 3 Pages: 403-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Anti-cancer approach with NK4 : Bivalent action and mechanisms.2010
- Author(s)
  Nakamura T, Sakai K, Nakamura T, Matsumoto K.
- Journal Title
  
  Anti-Cancer Agent Med. Chem. 10(1)
  
  Pages: 36-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] p27 Nuclear localization and growth arrest caused by perlecan knockdown in human endothelial cells2010
- Author(s)
  Sakai K, Matsumoto K, et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 3
  
  Pages: 403-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] p27 Nuclear localization and growth arrest caused by perlecan knockdown in human endothelial cells.2010
- Author(s)
  Sakai K, Oka K, Matsumoto K, Nakamura T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 392
  
  Pages: 403-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Anti-cancer approach with NK4 : Bivalent action and mechanisms.2010
- Author(s)
  Nakamura T, Sakai K, Nakamura T,Matsumoto K.
- Journal Title
  
  Anti-cancer Agent Med.Chem.
  
  Volume: 10 Pages: 36-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Inhibition of Met/HGF receptor and angiogenesis by NK4 leads to suppression of tumor growth and migration in malignant pleural mesothelioma.2010
- Author(s)
  Suzuki Y, Sakai K, Ueki J, Xu Q, Nakamura T, Shimada H, Nakamura T, Matsumoto K.
- Journal Title
  
  Int.J.Cancer 127
  
  Pages: 1948-1957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Inhibition of Met/HGF receptor and angiogenesis by NK4 leads to suppression of tumor growth and migration in malignant pleural mesothelioma.2010
- Author(s)
  Suzuki Y, Sakai K, Ueki J, Xu Q, Nakamura T, Shimada H, Nakamura T, Matsumoto K.
- Journal Title
  
  Int.J.Cancer
  
  Volume: 127 Pages: 1948-1957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Angioinhibitory action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association2009
- Author(s)
  Sakai K, Matsumoto K, et al.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 22491-22499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Angioinhibitory Action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association.2009
- Author(s)
  Sakai K, Nakamura T, Matsumoto K, Nakamura T.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 22491-22499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Hepatocyte Growth Factor and Met in Tumor Biology and Therapeutic Approach with NK4.2008
- Author(s)
  Matsumoto K, Nakamura T, Sakai K, Nakamura T.
- Journal Title
  
  Proteomics 8
  
  Pages: 3360-3370
- NAID
  120001130499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Patent] 人工タンパク質及び医薬組成物2022
- Inventor(s)
  佐古佑介，平井秀憲，松本邦夫，酒井克也
- Industrial Property Rights Holder
  佐古佑介，平井秀憲，松本邦夫，酒井克也
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20K06553
[Patent] 環状ペプチド2018
- Inventor(s)
  酒井克也
- Industrial Property Rights Holder
  酒井克也
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16K08544
[Presentation] Expanding therapeutic potential of growth factors by lasso-grafting.2022
- Author(s)
  Sakai K, Rojas-Chaverra NM, Sato H, Imamura R, Voon CCD, Suga H, Takagi J, Matsumoto K.
- Organizer
  Duke-NUS-KUCRI Junior Staff Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-20K06553
[Presentation] ラッソグラフトを用いた人工成長因子による治療可能性の拡大2022
- Author(s)
  酒井克也, Rojas-Chaverra NM, 揚山直英, 片貝祐子, 高木淳一, 菅裕明, 松本邦夫
- Organizer
  霊長類医科学フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-20K06553
[Presentation] 環状ペプチドファルマコフォア内挿型の組換えアゴニストによる組織再生治療の試み2021
- Author(s)
  酒井克也，三原恵美子，中村希，渡邉咲耶子，佐藤拓輝，今村龍，菅裕明，高木淳一，松本邦夫
- Organizer
  第94回生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06553
[Presentation] 環状ペプチドとタンパク質エンジニアリングに基づく人工Met受容体アゴニスト2020
- Author(s)
  酒井克也
- Organizer
  第15回生命医科学研究所ネットワーク国際シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06553
[Presentation] MET受容体の人為制御と構造基盤2020
- Author(s)
  酒井克也, 高木淳一, 菅裕明, 柴田幹大, 松本邦夫
- Organizer
  第９３回日本生化学会大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06553
[Presentation] Peptide-grafted Proteins and Nanometorology for Targeting and Understanding of Growth Factor Receptor2020
- Author(s)
  酒井克也
- Organizer
  1st WPI NanoLSI-iCeMS Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06553
[Presentation] Single-molecule nano-scale observation of growth factor and receptor2019
- Author(s)
  Sakai Katsuya
- Organizer
  第78回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08544
[Presentation] 選択的生物活性をもつ環状ペプチドによるMET/HGF受容体アゴニストの創成2018
- Author(s)
  Miao Wenyu、酒井克也、伊藤健一郎、菅裕明、松本邦夫
- Organizer
  第91回日本生化学会
- Data Source
  KAKENHI-PROJECT-16K08544
[Presentation] PET imaging system reflecting activation status of HGF/Met signalling with macro-cyclic peptides.2018
- Author(s)
  Sato H, Sakai K, Mukai H, Watanabe Y, Passioura T, Suga H, Matsumoto K.
- Organizer
  The 1st NanoLSI International Symposium.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08544
[Presentation] Activation and detection of Met/HGF receptor by cyclic peptide technology2017
- Author(s)
  Wenyu Miao, Katsuya Sakai, Naoya Ozawa, Kenichiro Ito, Hiroaki Suga, Kunio Matsumoto
- Organizer
  第76回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08544
[Presentation] Cellular Signaling and Gene Expression Profiles Evoked by Artificial MET/HGF Receptor-Agonist of Macrocyclic Peptide2017
- Author(s)
  Wenyu Miao, Katsuya Sakai, Naoya Ozawa, Kenichiro Ito, Hiroaki Suga, Kunio Matsumoto
- Organizer
  11th International Symposium of The Institute Network
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08544
[Presentation] Cellular Signaling and Gene Expression Profiles Evoked by Artificial MET/HGF Receptor-Agonist of Macrocyclic Peptide2017
- Author(s)
  Wenyu Miao, Katsuya Sakai, Naoya Ozawa, Kenichiro Ito, Hiroaki Suga, Kunio Matsumoto
- Organizer
  第90回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08544
[Presentation] B16F10メラノーマの造腫瘍性/転移性におけるMet階層的発現の意義.2016
- Author(s)
  足立恵理、酒井克也、今村龍、松本邦夫
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] 特殊環状ペプチドによる人工Metアゴニスト.2016
- Author(s)
  Miao Wenyu、酒井克也、小澤直也、伊藤健一郎、菅裕明、松本邦夫
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター・東北大学仙台市
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] Purification and functional analyses of multi-functional cytokine Lect2.2016
- Author(s)
  今村　龍、Jangphattananont Nawaphat、酒井克也、松本邦夫
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] HGF/c-Metシグナリングの解明に向けた二本鎖HGFの構造決定．2016
- Author(s)
  海津　正賢、有森　貴夫、酒井克也、小笠原　諭、北郷悠、金子美華、加藤幸成、松本邦夫、高木　淳一
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] 特殊環状ペプチドによるMet/HGF受容体アゴニストの創製2015
- Author(s)
  松本邦夫、酒井克也、伊藤健一郎、菅裕明
- Organizer
  インターフェロン・サイトカイン学会
- Place of Presentation
  東京工業大学（東京都目黒区大岡山）
- Year and Date
  2015-07-18
- Invited
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] 環状ペプチドによる人工Met受容体アゴニストの創製2015
- Author(s)
  酒井克也、伊藤健一郎、菅裕明、松本邦夫
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] 悪性黒色腫におけるMet受容体の階層的発現に連動する腫瘍特性（薬剤耐性・転移性）制御2015
- Author(s)
  足立恵理、酒井克也、松本邦夫
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] 特殊環状ペプチドによる人工HGFの創製2015
- Author(s)
  松本邦夫、酒井克也、伊藤健一郎、菅裕明
- Organizer
  肝細胞研究会
- Place of Presentation
  米子コンベンションセンター（鳥取県米子）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15K14473
[Presentation] CBX/PRCのプロテアソーム分解を介したヒト悪性中皮腫細胞の浸潤性制御.2014
- Author(s)
  平井智子、酒井克也、鈴木健之、矢野聖二、高橋智聡、西内巧、松本邦夫
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都（京都国際会議場）
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] 三次元コラーゲンゲル共培養モデルを利用したがん浸潤機構の研究: HGFとTGF-βの役割.2014
- Author(s)
  宮崎香、小柳潤、東昌市、菊池慶司、酒井克也、松本邦夫
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  横浜（パシフィコ横浜）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] Met/HGF受容体を標的とする環状ペプチドの創製.2014
- Author(s)
  松本邦夫、酒井克也、伊藤健一郎、菅裕明
- Organizer
  第73回日本癌学会総会シンポジウム
- Place of Presentation
  横浜（パシフィコ横浜）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] B16F10メラノーマの造腫瘍性/転移性におけるMet階層的発現の意義.2014
- Author(s)
  足立恵理、酒井克也、松本邦夫
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  横浜（パシフィコ横浜）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] Dysfunction of polycomb group CBX protein is possibly involved in tumor malignancy2013
- Author(s)
  Sakai K, Nakamura T, Suzuki Y, Suzuki T, Yano S, Takahashi C, and Matsumoto K
- Organizer
  第3回新学術領域発がんスパイラル国際シンポジウム&金沢国際がん生物学シンポジウム
- Place of Presentation
  金沢エクセルホテル東急(石川県)
- Data Source
  KAKENHI-PROJECT-23790221
[Presentation] マウス乳腺上皮細胞における4倍体細胞の形成と増殖能の解析2012
- Author(s)
  酒井克也、松本邦夫
- Organizer
  第71回日本癌学会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23790221
[Presentation] マウス乳腺上皮細胞における4倍体細胞の形成と増殖能の解析2012
- Author(s)
  酒井克也
- Organizer
  日本癌学会
- Place of Presentation
  ロイトン札幌 (北海道)
- Data Source
  KAKENHI-PROJECT-23790221
[Presentation] Aberrant Regulation of Epigenetic Silencing in 3-D Tumor Invasion2012
- Author(s)
  Katsuya Sakai
- Organizer
  Japan - Korea Cancer Research Workshop
- Place of Presentation
  Westin Chosun Hotel (Busan, Korea)
- Data Source
  KAKENHI-PROJECT-23790221
[Presentation] Aberrant regulation of epigenetic silencing in 3-D tumor invasion.2012
- Author(s)
  Katsuya Sakai
- Organizer
  The 17th Japan-Korea Cancer Research Workshop
- Place of Presentation
  韓国
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] マウス乳腺上皮細胞における4倍体細胞の形成と増殖能の解析.2012
- Author(s)
  酒井克也
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] Epigenetic dysregulation of MMP-2 expression confers mesothelioma cell invasion2011
- Author(s)
  Sakai K, Yano S, Matsumoto K
- Organizer
  日本分子生物学会第11回春季シンポジウム&金沢国際がん生物学会シンポジウム
- Place of Presentation
  石川県立音楽堂(石川県)
- Data Source
  KAKENHI-PROJECT-23790221
[Presentation] Aberrant Regulation of Epigenetic Silencing in 3-D Tumor Invasion2011
- Author(s)
  Sakai K, Matsumoto K
- Organizer
  Japan - Korea Cancer Research Workshop
- Place of Presentation
  Westin Chosun Hotel (Korea)
- Data Source
  KAKENHI-PROJECT-23790221
[Presentation] Perlecanによるp27の発現ならびに細胞内細胞内局在の制御を介した血管内皮細胞の増殖制御.2010
- Author(s)
  酒井克也、松本邦夫, (他3 名)
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] Pcrlecanによるp27の発現ならびに細胞内細胞内局在の制御を介した血管内皮細胞の増殖制御2010
- Author(s)
  酒井克也、岡清正、中村隆弘、松本邦夫、中村敏一
- Organizer
  第33回日本分子生物学会年会・日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] Perlecanによるp27の発現ならびに細胞内細胞内局在の制御を介した血管内皮細胞の増殖制御2010
- Author(s)
  酒井克也、松本邦夫, (他3名)
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] NK4によるプロテオグリカン結合を介したフィブロネクチン構築阻害2009
- Author(s)
  酒井克也, 松本邦夫, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] NK4による血管新生阻害作用の解析-プロテオグリカン結合を介したフィブロネクチン構築阻害.2009
- Author(s)
  酒井克也、松本邦夫, (他3名)
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] HGF-Met系を介したヒト悪性中皮腫細胞の遊走制御とMet細胞外領域遺伝子変異2009
- Author(s)
  酒井克也、松本邦夫, (他3名)
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] NK4による血管新生阻害作用の解析・プロテオグリカン結合を介したフィブロネクチン構築阻害2009
- Author(s)
  酒井克也, 松本邦夫, 他
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場 (兵庫県)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] NK4によるプロテオグリカン結合を介したフィブロネクチン構築阻害2009
- Author(s)
  酒井克也、松本邦夫, (他3名)
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] MMPに依存したヒト悪性中皮腫のコラーゲンマトリックス内浸潤.2008
- Author(s)
  酒井克也, 松本邦夫, 他
- Organizer
  第31回日本分子生物学余年会・第81回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] マトリックスメタロプロテアーゼに依存したヒト悪性中皮腫のコラーゲンマトリックス内浸潤.2008
- Author(s)
  酒井克也、松本邦夫, (他3名)
- Organizer
  第31回に本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] マトリックスメタロプロテアーゼに依存したヒト悪性中皮腫のコラーゲンマトリックス内浸潤.2008
- Author(s)
  酒井克也、松本邦夫, (他3名)
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] マトリツクスメタロプロテアーゼに依存したヒト悪性中皮腫のコラーゲン内浸潤.2008
- Author(s)
  酒井克也, 松本邦夫, 他
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] TGF-β阻害剤はin vitroにおいて線維芽細胞のHGF産生の亢進を介してがん細胞の浸潤を促進する.
- Author(s)
  小柳潤、東昌市、菊地慶司、酒井克也、松本邦夫、宮崎香
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] Kremenによる肺がん細胞におけるWnt/β-cateninシグナルの調節.
- Author(s)
  中村隆弘、酒井克也、足立恵理、松本邦夫
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] c-Metのダウンレギュレーションを伴わない新規PGI2アゴニスト反復投与の血管新生作用.
- Author(s)
  櫨川舞、松本邦夫、酒井芳紀、原口珠実、吉田都、内田享弘
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本（熊本県）
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] がん悪性化におけるポリコーム群クロモボックスタンパク質の機能.
- Author(s)
  酒井克也、鈴木健之、矢野聖二、高橋智聡、松本邦夫
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] リポ酸によるヒト肺がん細胞増殖抑制機構の解析.
- Author(s)
  松郷誠一、道越洸充、中村隆弘、酒井克也、松本邦夫
- Organizer
  第8回α―リポ酸研究会
- Place of Presentation
  富山国際会議場（富山県）
- Data Source
  KAKENHI-PROJECT-24300329

1. MATSUMOTO Kunio (90201780)

# of Collaborated Projects: 3 results

# of Collaborated Products: 59 results
2. NAKAMURA Takahiro (70414018)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
3. SUGA Hiroaki (00361668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. AOKI Shunsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. WANG Wei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. YAMADA Tadaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. NATSUME Tohru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 高木淳一

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
9. 高田穣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 瀧川奈義夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 市原英基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 木浦勝行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 宮崎香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 矢野聖二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 鈴木健之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 佐田政隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 松田道行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 平島剛志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 角野歩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKAI KATSUYA 酒井 克也

Sakai Katsuya 酒井 克也

SAKAI Katsuya 酒井 克也

Research Projects

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Co-Researchers

変異成長ホルモン受容体の機能検証と人工リガンドによる救済Principal Investigator

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Mechanism and manipulation of growth factor receptors by bioactive peptides and AFMPrincipal Investigator

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Establishment of artificial ligands technology for peptide hormone receptors with functional mutationsPrincipal Investigator

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Signal characteristics of heatero-receptor coupling and generation of artificial ligand

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Mechanisms for malignant tumor progression based on acquisition of 3-D invasiveness and regulation of epithelial morphogenesis

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Research of dynamic differentiation and morphogenesis in 3-D epithelial tubulogenesisPrincipal Investigator

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Research on tissue regeneration regulated by Met/HGF receptor ON-OFF regulation

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[Book] ものづくり技術からみる再生医療ー細胞研究・創薬・治療ー2018

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[Book] ペプチド医薬品の スクリーニング・安定化・製剤化技術2017

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[Book] 医療・診断をささえるペプチド科学2017

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[Book] Hepatocyte growth factor. In “Reference Module in BiomedicalSciences”2015

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[Book] "MspとMsp受容体"サイトカイン・増殖因子キーワード事典2015

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[Book] “MspとMsp受容体（Ron）”「サイトカイン・増殖因子キーワード事典」2015

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[Book] “Met/HGF受容体の制御”、「細胞膜受容体」（生体の科学）2013

Author(s)

SAKAI KATSUYA 酒井克也

Sakai Katsuya 酒井克也

SAKAI Katsuya 酒井克也

[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術2017

[Book] “HGF-Met系を標的とするがん創薬の意義と開発”、「次世代がん戦略研究update がん基盤生物学－革新的シーズ育成に向けて－」2013