IRIYAMA TAKAYUKI 入山高行

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Iriyama Takayuki 入山高行

入山高行イリヤマタカユキ

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Researcher Number	10570442
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 東京大学, 医学部附属病院, 准教授 2017 – 2022: 東京大学, 医学部附属病院, 講師 2015 – 2016: 東京大学, 医学部附属病院, 助教 2012: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields Except Principal Investigator Basic Section 53040:Nephrology-related / Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator 妊娠高血圧腎症 / ASK1 / シグナル伝達 / 炎症 / 早産 Except Principal Investigator 先天性腎尿路生殖器異常 / 女性生殖器形態異常 / 先天性腎尿路異常 / プラバスタチン / アンギオテンシン / 炎症性サイトカイン / 妊娠高血圧腎症 / 胎児脳障害

胎児毒性の排除を実現する、妊娠高血圧腎症に対する多角的な新規治療法の開発Principal Investigator
- Principal Investigator
  
  入山高行
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
先天性腎尿路生殖器症候群の発症メカニズム解明に向けた基礎的・臨床的アプローチ
- Principal Investigator
  
  神田祥一郎
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokyo
妊娠高血圧腎症に起因する児の高次脳機能障害の予防治療にむけた基礎的研究
- Principal Investigator
  
  瀬山貴博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
Development of a Novel Therapeutic Agent for Preeclampsia Using Micellar NanoparticlesPrincipal Investigator
- Principal Investigator
  
  IRIYAMA TAKAYUKI
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
自己免疫機序を標的とした妊娠高血圧腎症に対する新規治療法の開発Principal Investigator
- Principal Investigator
  
  入山高行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
Development of novel drug against preeclampsia targeting renin-angiotensin systemPrincipal Investigator
- Principal Investigator
  
  IRIYAMA TAKAYUKI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  The University of Tokyo
Investigation of placental adenosine signaling in the pathogenesis of preeclampsiaPrincipal Investigator
- Principal Investigator
  
  Iriyama Takayuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo
アデノシンシグナル経路を介した妊娠高血圧腎症の病態機序の解明と治療的可能性の検討Principal Investigator
- Principal Investigator
  
  入山高行
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo
早産発症機序の解明と分子標的治療に向けた基礎的研究Principal Investigator
- Principal Investigator
  
  入山高行
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokyo

All 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] Preeclampsia -Basic, Genomic, and Clinical2018
- Author(s)
  Iriyama T
- Total Pages
  290
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-16H06266
[Journal Article] Atomoxetine, a selective norepinephrine reuptake inhibitor, improves short-term histological outcomes after hypoxic-ischemic brain injury in the neonatal male rat.2018
- Author(s)
  Toshimitsu M, Kamei Y, Ichinose M, Seyama T, Imada S, Iriyama T, Fujii T.
- Journal Title
  
  Int J Dev Neurosci
  
  Volume: - Issue: 1 Pages: 34-45
- DOI
  10.1016/j.ijdevneu.2018.03.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10106, KAKENHI-PROJECT-16H06266
[Journal Article] Impact of Th1/Th2 cytokine polarity induced by invariant NKT cells on the incidence of pregnancy loss in mice2018
- Author(s)
  Hoya Mari、Nagamatsu Takeshi、Fujii Tatsuya、Schust Danny J.、Oda Hiroko、Akiba Naoya、Iriyama Takayuki、Kawana Kei、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 79 Issue: 3
- DOI
  10.1111/aji.12813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09220, KAKENHI-PROJECT-16H06266
[Journal Article] Elevation of maternal serum sFlt-1 in pregnancy with mirror syndrome caused by fetal cardiac failure2018
- Author(s)
  Katoh Yoshihisa、Seyama Takahiro、Mimura Nobuko、Furuya Hitomi、Nakayama Toshio、Iriyama Takayuki、Nagamatsu Takeshi、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Oxford Medical Case Reports
  
  Volume: 2018 Issue: 3
- DOI
  10.1093/omcr/omx112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02943, KAKENHI-PROJECT-16H06266
[Journal Article] Pretreatment with magnesium sulfate attenuates white matter damage by preventing cell death of developing oligodendrocytes.2018
- Author(s)
  Seyama T, Kamei Y, Iriyama T, Imada S, Ichinose M, Toshimitsu M, Fujii T, Asou H.
- Journal Title
  
  J Obstet Gynaecol Res.
  
  Volume: 44 Issue: 4 Pages: 601-607
- DOI
  10.1111/jog.13568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10106, KAKENHI-PROJECT-16H06266
[Journal Article] Tokishakuyakusan, a traditional Japanese medicine (Kampo) mitigates iNKT cell-mediated pregnancy loss in mice2018
- Author(s)
  Nagamatsu Takeshi、Fujii Tatsuya、Schust Danny J.、Tsuchiya Naoko、Tokita Yohei、Hoya Mari、Akiba Naoya、Iriyama Takayuki、Kawana Kei、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  American Journal of Reproductive Immunology
  
  Volume: 80 Issue: 4
- DOI
  10.1111/aji.13021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09220, KAKENHI-PROJECT-18H02943, KAKENHI-PROJECT-16H06266
[Journal Article] Enhanced HIF2α expression during human trophoblast differentiation into syncytiotrophoblast suppresses transcription of placental growth factor2017
- Author(s)
  Fujii Tatsuya、Nagamatsu Takeshi、Morita Kazuki、Schust Danny J.、Iriyama Takayuki、Komatsu Atsushi、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 12455-12455
- DOI
  10.1038/s41598-017-12685-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04979, KAKENHI-PROJECT-16H05469, KAKENHI-PROJECT-16H06266, KAKENHI-PROJECT-16K15700
[Presentation] 妊娠高血圧腎症における炎症性サイトカインの役割の検討～治療標的・予知マーカーとしての可能性の探求～2017
- Author(s)
  入山高行
- Organizer
  日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-16H06266
[Presentation] 胎盤での過剰なアデノシグナルを介した妊娠高血圧腎症の発症機序の解明2016
- Author(s)
  入山高行
- Organizer
  日本妊娠高血圧学会
- Place of Presentation
  埼玉県大宮市
- Invited
- Data Source
  KAKENHI-PROJECT-16H06266
[Presentation] Hypoxia-independent upregulation of placental hypoxia-inducible factor-1α contributes to the pathogenesis of preeclampsia2016
- Author(s)
  Takayuki Iriyama, Yutaka Osuga, Tomoyuki Fujii
- Organizer
  第68回日本産科婦人科学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-15H06171
[Presentation] 妊娠高血圧腎症の病態形成における自己抗体の関与2016
- Author(s)
  入山高行
- Organizer
  日本生殖免疫学会
- Place of Presentation
  兵庫県神戸市
- Invited
- Data Source
  KAKENHI-PROJECT-16H06266
[Presentation] 胎盤でのCD73依存的なアデノシンの過剰蓄積とA2Bアデノシン受容体の活性化が妊娠高血圧腎症の発症に関与する2015
- Author(s)
  入山高行、大須賀穣、藤井知行
- Organizer
  第30回日本生殖免疫学会
- Place of Presentation
  熊本県熊本市
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-15H06171

1. 瀬山貴博 (30529079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 熊澤惠一 (90444546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 神田祥一郎 (60632651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 藤代準 (60528438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 西裕志 (90784174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAGAMATSU Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 亀井良政

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 藤井知行

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

IRIYAMA TAKAYUKI 入山 高行

Iriyama Takayuki 入山 高行

入山 高行 イリヤマ タカユキ

Research Projects

Research Products

Co-Researchers

胎児毒性の排除を実現する、妊娠高血圧腎症に対する多角的な新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

先天性腎尿路生殖器症候群の発症メカニズム解明に向けた基礎的・臨床的アプローチ

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

妊娠高血圧腎症に起因する児の高次脳機能障害の予防治療にむけた基礎的研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a Novel Therapeutic Agent for Preeclampsia Using Micellar NanoparticlesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自己免疫機序を標的とした妊娠高血圧腎症に対する新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel drug against preeclampsia targeting renin-angiotensin systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of placental adenosine signaling in the pathogenesis of preeclampsiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アデノシンシグナル経路を介した妊娠高血圧腎症の病態機序の解明と治療的可能性の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

早産発症機序の解明と分子標的治療に向けた基礎的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Preeclampsia -Basic, Genomic, and Clinical2018

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Atomoxetine, a selective norepinephrine reuptake inhibitor, improves short-term histological outcomes after hypoxic-ischemic brain injury in the neonatal male rat.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of Th1/Th2 cytokine polarity induced by invariant NKT cells on the incidence of pregnancy loss in mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elevation of maternal serum sFlt-1 in pregnancy with mirror syndrome caused by fetal cardiac failure2018

Author(s)

Journal Title

DOI

Data Source

IRIYAMA TAKAYUKI 入山高行

Iriyama Takayuki 入山高行

入山高行イリヤマタカユキ