AIBA YUICHIRO 愛場雄一郎

… Alternative Names

Aiba Yuichiro 愛場雄一郎

AIBA Yuichiro 愛場雄一郎

愛場雄一郎アイバユウイチロウ

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Researcher Number	10581085
Other IDs
Affiliation (Current)	2026: 名古屋大学, 理学研究科, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 名古屋大学, 理学研究科, 准教授 2020: 名古屋大学, 理学研究科, 講師 2019: 名古屋大学, 理学研究科, 助教 2016 – 2017: 名古屋大学, 理学研究科, 助教 2015: 筑波大学, 生命領域学際研究センター, 研究員 2010: The University of Tokyo, 先端科学技術研究センター, 特任助教 2007 – 2008: The University of Tokyo, 大学院・工学系研究科, 特別研究員(DC1)
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related / Chemistry related to living body / Bio-related chemistry / Chemistry related to living body Except Principal Investigator Chemistry / Science and Engineering
Keywords	Principal Investigator PNA / 核酸 / DNA / 遺伝子 / インベージョン / ペプチド核酸 / ゲノム / バイオテクノロジー / ペプチド / 人工核酸 … More / セシウム(IV) / 加水分解 / 制限酵素 / 遺伝子組換え / 位置選択的切断 / セリウム(IV) / Argonauto / 蛋白質 / RNA干渉 / Argonaute … More Except Principal Investigator バイテクノロジー / 相同組換え / 人工酵素 / ペプチド / 相同組替え / ゲノム編集 / 遺伝子操作 / 核酸 / バイオテクノロジー / 遺伝子 / ゲノム / セリウム / 遺伝子組換え / ペプチド核酸 / 制限酵素 / DNA Less

Development of PNA toward intracellular nucleic acid manipulationPrincipal Investigator
- Principal Investigator
  
  AIBA Yuichiro
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Nagoya University
Development of peptide nucleic acids recognizing double-stranded DNA with high efficiencyPrincipal Investigator
- Principal Investigator
  
  Aiba Yuichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Nagoya University
DNA scission activity of Thermus thermophilus Argonaute with artificial nucleic acidsPrincipal Investigator
- Principal Investigator
  
  Aiba Yuichiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bio-related chemistry
- Research Institution
  Nagoya University
Construction of stabilized PNA/DNA invasion complex for the analysis of higher-order structure of DNAPrincipal Investigator
- Principal Investigator
  
  AIBA Yuichiro
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Chemistry related to living body
- Research Institution
  The University of Tokyo
Creation of genome manipulation technology using super restriction enzyme
- Principal Investigator
  
  KOMIYAMA Makoto
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  University of Tsukuba
  The University of Tokyo
セリウム触媒を利用した人工制限酵素の高機能化および遺伝子操作への応用Principal Investigator
- Principal Investigator
  
  愛場雄一郎
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Chemistry related to living body
- Research Institution
  The University of Tokyo

[Journal Article] Recognition of mismatched sites in double-stranded DNA by a pair of partially noncomplementary peptide nucleic acids2024
- Author(s)
  Shibata Masanari、Shoji Osami、Aiba Yuichiro
- Journal Title
  
  Chemistry Letters
  
  Volume: 53 Issue: 12
- DOI
  10.1093/chemle/upae234
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05350
[Journal Article] Sequence-Specific Recognition of Double-Stranded DNA by Using Only PNAs in Parallel with Natural Nucleobases2022
- Author(s)
  Shibata Masanari、Aiba Yuichiro、Hibino Masaki、Shoji Osami
- Journal Title
  
  ChemRxiv
  
  Volume: -
- DOI
  10.26434/chemrxiv-2022-wq3dm
- Open Access
- Data Source
  KAKENHI-PROJECT-22K05350
[Journal Article] Sequence-Specific Recognition of Double-Stranded DNA by Peptide Nucleic Acid Forming Double-Duplex Invasion Complex2022
- Author(s)
  Aiba Yuichiro、Shibata Masanari、Shoji Osami
- Journal Title
  
  Applied Sciences
  
  Volume: 12 Issue: 7 Pages: 3677-3677
- DOI
  10.3390/app12073677
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05730, KAKENHI-PROJECT-22KJ1567, KAKENHI-PROJECT-22K05350
[Journal Article] Investigation of the Characteristics of NLS-PNA: Influence of NLS Location on Invasion Efficiency2020
- Author(s)
  Aiba Yuichiro、Urbina Gerardo、Shibata Masanari、Shoji Osami
- Journal Title
  
  Applied Sciences
  
  Volume: 10 Issue: 23 Pages: 8663-8663
- DOI
  10.3390/app10238663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05730
[Journal Article] Cationic Guanine: Positively Charged Nucleobase with Improved DNA Affinity Inhibits Self-Duplex Formation2019
- Author(s)
  Hibino,M.; Aiba,Y.; Shoji,O.
- Journal Title
  
  Chem. Commun
  
  Volume: 56 Issue: 17 Pages: 2546-2549
- DOI
  10.1039/d0cc00169d
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05806, KAKENHI-PROJECT-19K05730
[Journal Article] Promotion of double-duplex invasion of peptide nucleic acid through conjugation with nuclear localization signal peptide2015
- Author(s)
  Y. Aiba, Y. Honda, M. Komiyama
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 21 Issue: 10 Pages: 4021-4026
- DOI
  10.1002/chem.201406085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007
[Journal Article] Affinity-isolation of desired restriction fragment from human genome using double-duplex invasion of biotin-bound pseudo-complementary PNA.2015
- Author(s)
  N. Shigi, A. Rajendran, X. Wang, H. Kunifuda, J. Sumaoka, M. Komiyama
- Journal Title
  
  Chem. Lett.
  
  Volume: 44 Issue: 11 Pages: 1569-1571
- DOI
  10.1246/cl.150682
- NAID
  130005108088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007, KAKENHI-PROJECT-15H02189
[Journal Article] PNA-NLS conjugates as single-molecular activators of target sites in double-stranded DNA for site-selective scission2013
- Author(s)
  Y. Aiba, Y. Hamano, W. Kameshima, Y. Araki, T. Wada, A. Accetta, S. Sforza, R. Corradini, R. Marchelli, and M. Komiyama
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 11 Issue: 32 Pages: 5233-5238
- DOI
  10.1039/c3ob40947c
- NAID
  120007130454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007, KAKENHI-PLANNED-24120005, KAKENHI-PROJECT-24245044
[Journal Article] Site-selective scission of double-stranded DNA by combining a triplex-forming bis-PNA and Ce (IV)/EDTA2013
- Author(s)
  Y. Aiba, K. Yasuda. and M. Komiyama
- Journal Title
  
  Chemistry Letters
  
  Volume: 42 Issue: 10 Pages: 1300-1302
- DOI
  10.1246/cl.130650
- NAID
  10031201345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007
[Journal Article] Introduction of multiphosphonate ligand to peptide nucleic acid for metal ion conjugation.2012
- Author(s)
  Y. Aiba
- Journal Title
  
  Artificial DNA: PNA & XNA
  
  Volume: 3 Issue: 2 Pages: 73-79
- DOI
  10.4161/adna.20727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007
[Journal Article] Artificial site-selective DNA cutters to manipulate single-stranded DNA.2012
- Author(s)
  Y. Aiba
- Journal Title
  
  Polym. J.
  
  Volume: 52 Issue: 9 Pages: 413-435
- DOI
  10.1038/pj.2012.37
- NAID
  10031008879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007
[Journal Article] Artificial DNA Cutters for DNA Manipulation and Genome Engineering2011
- Author(s)
  Y.Aiba, J.Sumaoka, M.Komiyama
- Journal Title
  
  Chemical Society Reviews 10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22850004
[Journal Article] Manipulation of Single-Stranded DNA using artificial site-selective DNA cutter composed of Ce(IV)/EDTA and phosphonate-oligonucleotide conjugates.2011
- Author(s)
  Y.Aiba, T,Lonnberg, M.Komiyama
- Journal Title
  
  Chemistry-An Asian Journal
  
  Volume: accepted
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22850004
[Journal Article] Artificial DNA cutters for DNA manipulation and genome engineering.2011
- Author(s)
  Y. Aiba
- Journal Title
  
  Chem. Soc. Rev.
  
  Volume: 40 Issue: 12 Pages: 5657-5668
- DOI
  10.1039/c1cs15039a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007
[Journal Article] Manipulation of Single-Stranded DNA Using Artificial Site-Selective DNA Cutter Composed of Ce(IV)/EDTA and Phosphonate- Oligonucleotide Conjugates2011
- Author(s)
  Y.Aiba, T.Lonnberg, M.Komiyama
- Journal Title
  
  Chemistry-An Asian Journal (accepted.)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22850004
[Journal Article] Artificial DNA cutters for DNA manipulation and genome engineering.2011
- Author(s)
  Y.Aiba, J.Sumaoka, M.Komiyama
- Journal Title
  
  Chemical Society Reviews
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22850004
[Journal Article] Oxidation of Oligonucleotide-bound CeIII/Multiphosphonate Complex for Site-Selective DNA Scission2010
- Author(s)
  T.Lonnberg, Y.Aiba, Y.Hamano, Y.Miyajima, J.Sumaoka, M.Komiyama
- Journal Title
  
  Chemistry-A European Journal 16
  
  Pages: 855-859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-07J03030
[Journal Article] Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5'-monophosphates bearing a biodegradable protecting group2010
- Author(s)
  A.Leisvuori, Y.Aiba, T.Lonnberg, P.Poijarvi-Virta, L.Blatt, L.Beigelman, H.Lonnberg
- Journal Title
  
  Organic & Biomolecular Chemistry (掲載確定, In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-07J03030
[Journal Article] Manipulation of single-stranded DNA using artificial site-selective DNA cutter composed of Ce(IV)/EDTA and phosphonate-oligonucleotide conjugates2010
- Author(s)
  Y.Aiba, M.Komiyama
- Journal Title
  
  Chem.Asian J.
  
  Volume: 6 Pages: 2407-2411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22000007
[Journal Article] Handy and Prompt DNA Separation Using PNA with Internal Disulfide Bond2009
- Author(s)
  Y.Aiba, M.Komiyama
- Journal Title
  
  Nucleic Acids Symp.Ser. 53
  
  Pages: 175-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-07J03030
[Journal Article] Introduction of Disulfide Bond to the Main Chain of PNA to Switch Its Hybridization and Invasion Activity2009
- Author(s)
  Y.Aiba, M.Komiyama
- Journal Title
  
  Organic & Biomolecular Chemistry 7
  
  Pages: 5078-5083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-07J03030
[Journal Article] Introduction of linkers into PNA for versatile applications2008
- Author(s)
  Y. Aiba, M. Komiyama
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 143-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-07J03030
[Journal Article] スーパー制限酵素ARCUTによる新規遺伝子操作法の開発2007
- Author(s)
  愛場雄一郎
- Journal Title
  
  細胞工学 26
  
  Pages: 1296-1302
- Data Source
  KAKENHI-PROJECT-07J03030
[Patent] インベージョン複合体の形成方法2019
- Inventor(s)
  愛場雄一郎、荘司長三
- Industrial Property Rights Holder
  国立大学法人名古屋大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-132460
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] ペプチド核酸（PNA）を用いた核酸・ペプチド研究2025
- Author(s)
  愛場雄一郎
- Organizer
  13th BRIGHT Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Formation of Invasion Complexes with Shifted Parallel PNAs2025
- Author(s)
  Naoya Mochizuki、Masanari Shibata、Yuichiro Aiba、Kota Ito、Shinya Ariyasu、Osami Shoji
- Organizer
  GTR成果報告会（2024）
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Formation of Invasion Complexes Using Multiple Pairs of Parallel-Stranded PNAs2025
- Author(s)
  望月直哉、柴田将成、愛場雄一郎、伊藤公太、有安真也、荘司長三
- Organizer
  日本化学会第105春季年会（2025）
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸PNAの2本鎖形成を利用したペプチドの膜透過性発現2025
- Author(s)
  窪田英雄、愛場雄一郎、有安真也、荘司長三
- Organizer
  日本化学会第105春季年会（2025）
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチドへのペプチド核酸（PNA）連結によるsplit GFPの蛍光スイッチング2024
- Author(s)
  愛場雄一郎、塩澤駿清、渡瀬瑞希、有安真也、荘司長三
- Organizer
  第34回バイオ・高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] 認識領域をずらしたparallel型PNAによる2本鎖DNAへのインベージョン2024
- Author(s)
  望月直哉、柴田将成、愛場雄一郎、伊藤公太、有安真也、荘司長三
- Organizer
  日本化学会第104春季年会（2024）
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Promotion of DNA recognition by Multiple Pairs of Shifted Parallel PNAs2024
- Author(s)
  Naoya Mochizuki、Masanari Shibata、Yuichiro Aiba、Kota Ito、Shinya Ariyasu、Osami Shoji
- Organizer
  GTR成果報告会（2024）
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Sequence-specific recognition of double-stranded DNA using parallel-stranded peptide nucleic acids2024
- Author(s)
  Yuichiro Aiba、Masanari Shibata、Kotaro Nagoshi、Shinya Ariyasu、Osami Shoji
- Organizer
  20th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Development of artificial biomolecules for functions beyond natural biomolecules2024
- Author(s)
  Yuichiro Aiba
- Organizer
  6th IRTG Joint Symposium University of Munster and Nagoya University
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Recongnition of Double-Stranded DNA with Shifted Parallel PNAs2024
- Author(s)
  望月直哉、柴田将成、愛場雄一郎、伊藤公太、有安真也、荘司長三
- Organizer
  学際統合物質科学研究機構（IRCCS）成果報告会・産学ワークショップ
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸PNAを用いたペプチドおよび核酸研究2024
- Author(s)
  愛場雄一郎
- Organizer
  2024 第13回化学フロンティア研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Improved Double-Stranded DNA Recognition by Invasion Using Multiple Pairs of Parallel PNAs2024
- Author(s)
  Naoya Mochizuki、Masanari Shibata、Yuichiro Aiba、Kota Ito、Shinya Ariyasu、Osami Shoji
- Organizer
  The 3rd International Symposium on Biofunctional Chemistry 2024 (ISBC2024)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Improved Double-Stranded DNA Recognition via Invasion with Multiple Pairs of Parallel-Stranded Peptide Nucleic Acids(PNA)2024
- Author(s)
  Naoya Mochizuki、Masanari Shibata、Yuichiro Aiba、Shinya Ariyasu、Osami Shoji
- Organizer
  20th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Parallel-stranded peptide nucleic acids for specific recognition of double-stranded DNA and their structural analysis2024
- Author(s)
  Yuichiro Aiba、Masanari Shibata、Hiroshi Sugimoto、Osami Shoji
- Organizer
  XXV International Round Table on Nucleosides
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸（PNA）を用いたDNAとペプチドの認識・制御2024
- Author(s)
  愛場雄一郎
- Organizer
  第56回若手ペプチド夏の勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] 配列設計を利用したペプチド核酸（PNA）による2本鎖DNA認識2024
- Author(s)
  愛場雄一郎・柴田将成・日比野柾・有安真也・荘司長三
- Organizer
  第73回高分子討論会
- Invited
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] 核酸認識によるβストランド構造の制御に基づく化学発光のスイッチング2024
- Author(s)
  渡瀬瑞希、愛場雄一郎、塩澤駿清、有安真也、荘司長三
- Organizer
  第14回CSJ化学フェスタ2024
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] 二次構造を形成する核酸を標的としたペプチド核酸による液-液相分離制御2024
- Author(s)
  藤田宏貴、愛場雄一郎、相馬陸杜、有安真也、荘司長三
- Organizer
  第55回中部化学関係学協会支部連合秋季大会
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸（PNA）連結ペプチドによるsplit GFPの蛍光スイッチング2024
- Author(s)
  愛場雄一郎、塩澤駿清、渡瀬瑞希、有安真也、荘司長三
- Organizer
  第50回生体分子科学討論会・第3回生命金属科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸（PNA）の2本鎖形成を利用したペプチドの構造規定2024
- Author(s)
  窪田英雄、愛場雄一郎、有安真也、荘司長三
- Organizer
  第14回CSJ化学フェスタ2024
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Double-Stranded DNA Recognition with Multiple Pairs of Shifted Parallel PNAs2023
- Author(s)
  望月直哉、柴田将成、愛場雄一郎、伊藤公太、有安真也、荘司長三
- Organizer
  2023 International IRCCS-ILR-IRTG Symposium on “New Horizons of Molecular Functions”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸による二次構造を形成する核酸の相分離制御2023
- Author(s)
  藤田宏貴、愛場雄一郎、相馬陸杜、有安真也、荘司長三
- Organizer
  第49回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸PNAによる2本鎖DNAの直接認識2023
- Author(s)
  愛場雄一郎
- Organizer
  第7回 SPIRITS生物-無機-有機融合化学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸PNAによる新規2本鎖DNA認識技術の開発－化学修飾PNAについて－2023
- Author(s)
  愛場雄一郎、柴田将成
- Organizer
  第7回CeSPI-NUSR合同セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] 複数組のparallel型PNAを用いたインベージョンによる高効率なDNA認識2023
- Author(s)
  望月直哉、柴田将成、愛場雄一郎、伊藤公太、有安真也、荘司長三
- Organizer
  日本化学会第103春季年会（2023）
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Improved DNA Recognition by Invasion Using Multiple Consecutive Pairs of Shifted PNAs2023
- Author(s)
  Naoya Mochizuki, Masanari Shibata, Yuichiro Aiba, Kota Ito, Shinya Ariyasu, Osami Shoji
- Organizer
  GTR成果報告会(2023)
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸PNAの新規インベージョン法を用いた高効率なDNA認識2023
- Author(s)
  望月直哉、柴田将成、愛場雄一郎、伊藤公太、有安真也、荘司長三
- Organizer
  IRCCS成果報告会
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸（PNA）を用いた核酸の液-液相分離制御2023
- Author(s)
  愛場雄一郎、相馬陸杜、藤田宏貴、柴田将成、有安真也、荘司長三
- Organizer
  第33回バイオ・高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] N7位修飾グアニンによる人工核酸PNAの効率的なDNA認識2023
- Author(s)
  名越航太郎、愛場雄一郎、柴田将成、日比野柾、有安真也、荘司長三
- Organizer
  第54回中部化学関係学協会支部連合秋季大会
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] パラレル型PNAを用いたインベージョン手法の開発2023
- Author(s)
  愛場雄一郎、柴田将成、名越航太郎、望月直哉、有安真也、荘司長三
- Organizer
  ITbM/GTRコンソーシアム 2023年度第6回総会・第11回ワークショップ
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] 二本鎖DNAとのインベージョン複合体形成におけるparallel配向ペプチド核酸の特性評価2023
- Author(s)
  柴田将成、愛場雄一郎、日比野柾、荘司長三
- Organizer
  日本化学会第103春季年会（2023）
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸PNAによる新規2本鎖DNA認識技術の開発－Parallel型PNAインベージョンについて－2023
- Author(s)
  柴田将成、愛場雄一郎
- Organizer
  第7回CeSPI-NUSR合同セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Recognition of double-stranded DNA by peptide nucleic acid forming double-duplex invasion complex2023
- Author(s)
  Yuichiro Aiba
- Organizer
  2023 International IRCCS-ILR-IRTG Symposium on “New Horizons of Molecular Functions”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Double-Stranded DNA Recognition via Invasion with Multiple Pairs of Shifted Parallel PNAs2023
- Author(s)
  Naoya Mochizuki、Masanari Shibata、Kota Ito、Shinya Ariyasu、Yuichiro Aiba、Osami Shoji
- Organizer
  FIBER International Summit forNucleic Acids 2023(FISNA 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸による二次構造を形成する核酸の液-液相分離制御2023
- Author(s)
  藤田宏貴、愛場雄一郎、相馬陸杜、有安真也、荘司長三
- Organizer
  日本化学会秋季事業第13回 CSJ化学フェスタ2023
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸PNAの新規インベージョン法を用いた広範な標的DNAの認識2022
- Author(s)
  望月直哉、伊藤公太、柴田将成、愛場雄一郎、有安真也、荘司長三
- Organizer
  日本化学会秋季事業第12回CSJ化学フェスタ2022
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] 炭化水素基修飾グアニンによる人工核酸PNAの効率的なDNA認識2022
- Author(s)
  名越航太郎、愛場雄一郎、柴田将成、日比野柾、有安真也、荘司長三
- Organizer
  日本化学会秋季事業第12回CSJ化学フェスタ2022
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸（PNA）連結ペプチドを用いたsplit GFPシステムの開発2022
- Author(s)
  塩澤駿清、愛場雄一郎、有安真也、荘司長三
- Organizer
  第34回生物無機化学夏季セミナー
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] PNAの新規インベージョン法を用いた広範な標的DNAの認識2022
- Author(s)
  望月直哉、柴田将成、愛場雄一郎、有安真也、荘司長三
- Organizer
  日本化学会生体機能関連化学部会若手の会第33回サマースクール
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸（PNA）融合ペプチドを用いたsplit GFPシステムの開発2022
- Author(s)
  塩澤駿清、愛場雄一郎、有安真也、荘司長三
- Organizer
  第53回中部化学関係学協会支部連合秋季大会
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ペプチド核酸（PNA）によるDNA/RNA認識技術の開発2022
- Author(s)
  愛場雄一郎
- Organizer
  第9回ITbM/GTR コンソーシアムワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] 人工核酸PNAの配向性を利用した二本鎖DNA認識手法の開発2022
- Author(s)
  柴田将成、愛場雄一郎、日比野柾、杉本宏、荘司長三
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] ペプチド核酸（PNA）による核酸の液-液相分離制御2022
- Author(s)
  愛場雄一郎、相馬陸杜、柴田将成、有安真也、荘司長三
- Organizer
  第16回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] New Design of Peptide Nucleic Acids Recognizng Double-Stranded DNA2022
- Author(s)
  Masanari Shibata, Yuichiro Aiba, Masaki Hibino, Osami Shoji
- Organizer
  18th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Development of Modified Peptide Nucleic Acids Directly Recognizing Double-Stranded DNA2022
- Author(s)
  Yuichiro Aiba
- Organizer
  Webinar Universe 24 in 核酸化学ユニバース 14 (FIBER未来大学 FIBER FUTURE COLLEGE)
- Invited
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Improved Double-Stranded DNA Recognition by Chemically Modified Peptide Nucleic Acids (PNAs)2022
- Author(s)
  Yuichiro Aiba, Masaki Hibino, Masanari Shibata, Shinya Ariyasu, Osami Shoji
- Organizer
  10th Asian Biological Inorganic Chemistry (AsBIC10)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Effective Recognition of Target DNA Using a Novel Invasion Method of Peptide Nucleic Acid (PNA)2022
- Author(s)
  Naoya Mochizuki, Kota Ito, Masanari Shibata, Yuichiro Aiba, Shinya Ariyasu, Osami Shoji
- Organizer
  IRCCS-IRTG-GTR Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] 人工核酸PNAを用いたDNAの液-液相分離制御2022
- Author(s)
  相馬陸杜、愛場雄一郎、柴田将成、有安真也、荘司長三
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Development of Chemically Modified Peptide Nucleic Acids (PNAs) to Efficiently Recognize Double-Stranded DNA2022
- Author(s)
  Yuichiro Aiba, Masaki Hibino, Masanari Shibata, Shinya Ariyasu, Osami Shoji
- Organizer
  International Congress on Pure & Applied Chemistry Kota Kinabalu 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] ゲノムスケールDNA合成に向けた修飾PCRプライマーの合成効率向上2022
- Author(s)
  鈴木大輔、野村浩平、恩田馨、稲垣雅仁、阿部奈保子、橋谷文貴、木村康明、愛場雄一郎、阿部洋、荘司長三
- Organizer
  日本化学会秋季事業第12回CSJ化学フェスタ2022
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Positively charged guanine nucleobase to suppress self-duplex formation and improve PNA invasion efficiency2022
- Author(s)
  Yuichiro Aiba, Masaki Hibino, Kotaro Nagoshi, Masanari Shibata, Osami Shoji
- Organizer
  18th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05350
[Presentation] Positively charged nucleobase (G+) for inhibition of self duplex formation and improved PNA invasion efficiency2021
- Author(s)
  Yuichiro Aiba, Masaki Hibino, Kotaro Nagoshi, Masanari Shibata, Osami Shoji
- Organizer
  Pacifichem2021 Satellite Symposium -Modified DNA and XNA for therapeutic application-
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] ペプチド核酸（PNA）を用いた核酸の液-液相分離2021
- Author(s)
  愛場雄一郎、相馬陸杜、柴田将成、有安真也、荘司長三
- Organizer
  第5回LLPS研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 人工核酸PNAを用いた生体分子の液-液相分離2021
- Author(s)
  相馬陸杜、愛場雄一郎、柴田将成、有安真也、荘司長三
- Organizer
  第47回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] ペプチド核酸（PNA）の化学修飾による効率的な2本鎖DNA認識2021
- Author(s)
  愛場雄一郎、日比野柾、柴田将成、伊藤公太、有安真也、荘司長三
- Organizer
  第47回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 核酸認識を目指した核酸塩基修飾ペプチドの開発2021
- Author(s)
  塩澤駿清、愛場雄一郎、柴田将成、有安真也、荘司長三
- Organizer
  第11回CSJ化学フェスタ2021
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 天然核酸塩基からなるペプチド核酸（PNA）による配列特異的な 2本鎖DNA認識2021
- Author(s)
  愛場雄一郎、柴田将成、伊藤公太、日比野柾、有安真也、荘司長三
- Organizer
  第15回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] DNA 認識を目指した核酸塩基修飾 α ヘリックスペプチドの開発2021
- Author(s)
  塩澤駿清、愛場雄一郎、柴田将成、有安真也、荘司長三
- Organizer
  第47回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 連続した複数のペプチド核酸（PNA）を利用した効率的なDNA認識2021
- Author(s)
  伊藤公太、柴田将成、愛場雄一郎、日比野柾、有安真也、荘司長三
- Organizer
  第52回中部化学関係学協会支部連合秋季大会
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 人工核酸PNAを用いたDNAの液-液相分離2021
- Author(s)
  相馬陸杜、愛場雄一郎、柴田将成、有安真也、荘司長三
- Organizer
  第11回CSJ化学フェスタ2021
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] ペプチド核酸（PNA）による2本鎖DNAとのインベージョン複合体形成2021
- Author(s)
  愛場雄一郎、柴田将成、伊藤公太、日比野柾、有安真也、荘司長三
- Organizer
  第70回高分子討論会
- Invited
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] ペプチド核酸の配向性に着目した二本鎖DNA認識手法の開発2021
- Author(s)
  柴田将成、愛場雄一郎、日比野柾、荘司長三
- Organizer
  第31回バイオ・高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] PNAの配向性を利用した配列特異的な二本鎖DNA認識手法の開発2021
- Author(s)
  柴田将成、愛場雄一郎、日比野柾、伊藤公太、荘司長三
- Organizer
  日本化学会第 101 春季年会 (2021)
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] Sequence-selective recognition of double-stranded DNA2020
- Author(s)
  M. Shibata, M. Hibino, Y. Aiba, O. Shoji
- Organizer
  The 3rd IRCCS - The 2nd Reaction Infography Joint International Symposium: “Reaction Imaging Meets Materials Science”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 核酸の配向に着目したペプチド核酸による新規DNA認識法の開発2020
- Author(s)
  柴田将成、愛場雄一郎、日比野柾、荘司長三
- Organizer
  第14回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] ペプチド核酸・PNAによる２本鎖DNA認識2020
- Author(s)
  愛場雄一郎
- Organizer
  核酸化学懇話会 2020 北海道・東地区セミナー（次世代の核酸化学を考える）
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] ペプチド核酸PNAを用いたRNAプローブの開発2020
- Author(s)
  愛場雄一郎
- Organizer
  第11回加藤記念研究助成報告交流会
- Invited
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] インベージョン複合体の安定化による人工核酸PNAの効率的なDNA認識2020
- Author(s)
  伊藤公太、日比野柾、柴田将成、有安真也、愛場雄一郎、荘司長三
- Organizer
  第10回CSJ化学フェスタ2020
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] Peptide Chemistry2019
- Author(s)
  Y. Aiba
- Organizer
  ASUKA Symposium 2019　A New Phase of Regenerative Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] Sequence-selective Recognition of dsDNA by unmodified PNA2019
- Author(s)
  M. Shibata, M. Hibino, Y. Aiba, O. Shoji
- Organizer
  The 46th International Symposium on Nucleic Acids Chemistry (ISNAC 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] Chemically-modified peptide nucleic acids for their in cellulo applications2019
- Author(s)
  M. Shibata, Y. Aiba, M. Hibino, G. Urbina, Osami Shoji
- Organizer
  ASUKA Symposium 2019　A New Phase of Regenerative Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 人工核酸PNAを用いた新規二本鎖DNA認識法の開発2019
- Author(s)
  柴田将成、日比野柾、愛場雄一郎、荘司長三
- Organizer
  統合物質創製化学研究推進機構国内シンポジウム
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 汎用的なDNA認識法に向けた新規PNAインベージョンの開発2019
- Author(s)
  愛場雄一郎、柴田将成、日比野柾、荘司長三
- Organizer
  第13回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 化学の力で生物の機能を制御する-人工核酸を利用したDNA認識-2019
- Author(s)
  愛場雄一郎
- Organizer
  岡崎北高校大学講座
- Invited
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 人工核酸PNAを用いた新規二本鎖DNA認識法の開発2019
- Author(s)
  柴田将成、日比野柾、愛場雄一郎、荘司長三
- Organizer
  第9回CSJ化学フェスタ2019
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] Sequence Specific DNA Damage Induced by Metal-Complex-PNA Conjugate2019
- Author(s)
  M. Hibino, Y. Aiba, Y. Watanabe, O. Shoji
- Organizer
  19th International Conference on Biological Inorganic Chemistry (ICBIC-19)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] Inhibition of Self-duplex Formation by Using Methyl-adducted PNA2019
- Author(s)
  M. Hibino, Y. Aiba, O. Shoji
- Organizer
  Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] Double-duplex invasion complex formed by unmodified PNA for the recognition of double-stranded DNA2019
- Author(s)
  Y. Aiba, M. Shibata, M. Hibino, O. Shoji
- Organizer
  The 46th International Symposium on Nucleic Acids Chemistry (ISNAC 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 人工核酸PNAとペプチド・タンパク質との複合化によるDNA認識効率の向上2019
- Author(s)
  河内奈緒美、日比野柾、愛場雄一郎、荘司長三
- Organizer
  第50回中部化学関係学協会支部連合秋季大会
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] PNA with Metal-Coordinating Peptide for Sequence-Specific DNA Cleavage2019
- Author(s)
  M. Hibino, Y. Aiba, O. Shoji
- Organizer
  The 46th International Symposium on Nucleic Acids Chemistry (ISNAC 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 生理的条件下で機能する化学修飾ペプチド核酸（PNA）の開発2019
- Author(s)
  愛場雄一郎、日比野柾、河内奈緒美、柴田将成、荘司長三
- Organizer
  日本ケミカルバイオロジー学会　第14回年会
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] ペプチド核酸を用いた二本鎖DNAの配列選択的認識法の開発2019
- Author(s)
  柴田将成、日比野柾、愛場雄一郎、荘司長三
- Organizer
  第32回生物無機化学夏季セミナー
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 未修飾PNAによる二本鎖DNAの配列選択的認識2019
- Author(s)
  柴田将成、日比野柾、愛場雄一郎、荘司長三
- Organizer
  核酸化学若手フォーラム2019
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] Inhibition of Intra- and Intermolecular Interaction between Peptide Nucleic Acids2019
- Author(s)
  M. Hibino, Y. Aiba, O. Shoji
- Organizer
  NU-UoE JD and JSPS Core-to-Core Joint-Workshop on "New Horizons in Chemistry and Materials Science"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] Effective Sequence-selective Recognition of Double-stranded DNA via Invasion Complex Formation by Peptide Nucleic Acids2019
- Author(s)
  Y. Aiba, M. Shibata, M. Hibino, O. Shoji
- Organizer
  Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05730
[Presentation] 高度好熱菌由来Argonaute タンパク質への人工核酸の取り込みと効率的なDNA 切断2018
- Author(s)
  山口華苗、愛場雄一郎、荘司長三、渡辺芳人
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 原核生物由来Argonauteタンパク質と人工核酸を用いたＤＮＡ切断ツールの開発2017
- Author(s)
  山口華苗、愛場雄一郎、荘司長三、渡辺芳人
- Organizer
  第11回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 高度好熱菌由来Argonaute（TtAgo)への人工核酸導入によるDNA切断の高活性化2017
- Author(s)
  愛場雄一郎
- Organizer
  第30回生物無機化学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 高度好熱菌由来Argonauteによる位置選択的DNA切断2017
- Author(s)
  愛場雄一郎、山口華苗、荘司長三、渡辺芳人
- Organizer
  生体機能関連化学部会若手の会第29回サマースクール
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 高度好熱菌由来Argonaute(TtAgo)への人工核酸導入によるDNA切断の高活性化2017
- Author(s)
  愛場雄―郎、山口華苗、荘司長三、渡辺芳人
- Organizer
  第27回バイオ・高分子シンポジウム
- Place of Presentation
  東京
- Year and Date
  2017-07-27
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] Improved DNA scission activity of Thermus thermophiles Argonaute with artificial nucleic acids2017
- Author(s)
  Y. Aiba, K. Yamaguchi, O. Shoji, Y. Watanabe
- Organizer
  The 44th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 高度好熱菌由来Argonaute(TtAgo)への人工核酸導入によるDNA切断の高活性化2017
- Author(s)
  愛場雄一郎、山口華苗、荘司長三、渡辺芳人
- Organizer
  第27回バイオ・高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 高度好熱菌由来Argonauteタンパク質と人工核酸を用いたＤＮＡ切断ツールの開発2017
- Author(s)
  山口華苗、愛場雄一郎、荘司長三、渡辺芳人
- Organizer
  第5回バイオ関連化学シンポジウム若手フォーラム
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 人工核酸を用いた高度好熱菌由来Argonaute (TtAgo)の活性向上2016
- Author(s)
  山口華苗、愛場雄一郎、荘司長三、渡辺芳人
- Organizer
  第6回CSJ化学フェスタ2016
- Place of Presentation
  東京
- Year and Date
  2016-11-14
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 人工核酸による高度好熱菌由来Argonaute(TtAgo)の高活性化2016
- Author(s)
  山口華苗、愛場雄一郎、荘司長三、渡辺芳人
- Organizer
  第４回バイオ関連化学シンポジウム若手フォーラム
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 人工核酸を用いた遺伝子発現制御2016
- Author(s)
  愛場雄一郎
- Organizer
  みちのく分析科学シンポジウム2016
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 人工核酸を用いた高度好熱菌由来Argonaute (TtAgo)による効率的なDNA切断2016
- Author(s)
  愛場雄―郎、山口華苗、荘司長三、渡辺芳人
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 人工核酸を用いた高度好熱菌由来Argonaute(TtAgo)の高活性化2016
- Author(s)
  山口華苗、愛場雄一郎、荘司長三、渡辺芳人
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 核酸を対象とした遺伝子発現制御技術の開発2016
- Author(s)
  愛場雄―郎
- Organizer
  先導物質化学研究所講演会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-16K14032
[Presentation] 人工DNAカッター（ARCUT)による細胞内DNA切断2012
- Author(s)
  愛場　雄一郎 , 本田　祐太 , 韓　悦 , 亀島　渡 , 濱野　悠也 , 須磨岡　淳 , 鴫　成実 , 小宮山　眞
- Organizer
  第6回バイオ関連化学シンポジウム
- Place of Presentation
  北海道大学高等教育推進機構（北海道）
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] PNAへのNLS修飾によるインベージョンの高効率化とDNA切断への応用2012
- Author(s)
  愛場　雄一郎 , 本田　祐太 , 亀島　渡 , 濱野　悠 , Accetta Alessandro , Sforza Stefano , Marchelli Rosangela , Corradini Roberto , 小宮山　眞
- Organizer
  第22回バイオ・高分子シンポジウム
- Place of Presentation
  東京大学先端科学技術研究センター（東京）
- Year and Date
  2012-06-25
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] Ce(IV)/EDTAとペプチド核酸・ペプチドコンジュゲートによる位置選択的DNA切断2011
- Author(s)
  愛場雄一郎・濱野悠也・Accetta Alessandro・Sforza Stefano・Marchelli Rosangela・Corradini Roberto・小宮山眞
- Organizer
  第28回希土類討論会
- Place of Presentation
  タワーホール船堀(口頭発表)
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] 細胞内応用を志向した人工DNAカッター(ARCUT)の開発2011
- Author(s)
  愛場雄一郎・濱野悠也・本田祐太・亀島渡・菊池宏海・鴫成美・須磨岡淳・小宮山眞
- Organizer
  第21回バイオ・高分子シンポジウム
- Place of Presentation
  関西大学(口頭発表予定)
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] PNA-Peptide conjugateを利用したDNA位置選択的切断2011
- Author(s)
  愛場雄一郎・濱野悠也・Accetta Alessandro・Sforza Stefano・Marchelli Rosangela・Corradini Roberto・小宮山眞
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学(口頭発表)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] PNA Peptide eonjugateを利用したDNA位置選択的切断2011
- Author(s)
  愛場雄一郎、小宮山眞
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学(東日本大震災の影響で)(紙面・Web上での開催のみ)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] PNA-Peptide conjugateを利用したDNA位置選択的切断2011
- Author(s)
  ○愛場雄一郎・濱野悠也・A.Accetta・S.Sforza・R.Marchelli・R.Corradini・小宮山眞
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] PNA-peptide conjugateによる2重鎖DNA位置選択的切断への応用2011
- Author(s)
  愛場雄一郎・濱野悠也・亀島渡・Accetta Alessandro・Sforza Stefano・Marchelli Rosangela・Corradini Roberto・小宮山眞
- Organizer
  第60回高分子討論会
- Place of Presentation
  岡山大学(発表予定)
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] Incorporation of a flexible linker into pseudo-complementary PNA for the strict recognition of DNA2010
- Author(s)
  Yuichiro Aiba, Makoto Komiyama
- Organizer
  The 37th International Symposium on Nucleic Acids Chemistry 2010
- Place of Presentation
  Yokohama
- Year and Date
  2010-11-10
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] Incorporation of a flexible linker into pseudo-complementaly PNA for the strict recognition of DNA2010
- Author(s)
  ○Y.Aiba, Y.Nishiyama, M.Komiyama
- Organizer
  International Symposium on Nucleic Acids Chemistry 2010
- Place of Presentation
  Yokohama JAPAN
- Year and Date
  2010-11-10
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] 機能性リンカー導入による新規PNA修飾法の開発2010
- Author(s)
  愛場雄一郎・小宮山眞
- Organizer
  第22回生体機能関連化学部会若手の会サマースクール
- Place of Presentation
  三重県(ポスター発表)
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] 機能性リンカー導入による新規PNA修飾法の開発2010
- Author(s)
  愛場雄一郎、小宮山眞
- Organizer
  第22回生体機能関連化学部会若手の会サマースクール
- Place of Presentation
  三重県
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] 単一のPNA-peptideコンジュゲートを利用した位置選択的DNA切断2010
- Author(s)
  愛場雄一郎、小宮山眞
- Organizer
  第4回バイオ関連化学合同シンポジウム
- Place of Presentation
  大阪大学
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] 機能性リンカー導入による新規PNA修飾法の開発2010
- Author(s)
  愛場雄一郎・小宮山眞
- Organizer
  日本化学会生体機能関連化学部会若手の会サマースクール2010
- Place of Presentation
  三重県
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] 単一のPNA-peptideコンジュゲートを利用した位置選択的DNA切断2010
- Author(s)
  ○愛場雄一郎・濱野悠也・A.Accetta・S.Sforza・R.Marchelli・R.Corradini・小宮山眞
- Organizer
  第25回生体機能関連化学シンポジウム若手フォーラム
- Place of Presentation
  大阪大学
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] Site-selective scission of double-stranded DNA by Ce(IV)/EDTA and only one mixed-base PNA2010
- Author(s)
  Yuichiro Aiba, Makoto Komiyama
- Organizer
  PACIFICHEM 2010
- Place of Presentation
  Honolulu, USA
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] Strict recognition of double- stranded DNA by chemically modified PNA (Peptide Nucleic Acid).2010
- Author(s)
  Y.Aiba・M.Komiyama
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii, USA(ポスター発表)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] 単一のPNA-peptideコンジュゲートを利用した位置選択的DNA切断2010
- Author(s)
  愛場雄一郎、小宮山眞
- Organizer
  第25回生体機能関連化学シンポジウム若手フォーラム
- Place of Presentation
  大阪大学
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] Strict recognition of double-stranded DNA by chemically modified PNA (Peptide Nucleic Acid)2010
- Author(s)
  Yuichiro Aiba, Makoto Komiyama
- Organizer
  PACIFICHEM 2010
- Place of Presentation
  Honolulu, USA
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] Site-selective scission of double-stranded DNA by Ce(IV)/EDTA and only one mixed-base PNA2010
- Author(s)
  ○Y.Aiba, Y.Hamano, A.Accetta, S.Sforza, R.Marchelli, R.Corradini, M.Komiyama
- Organizer
  Pacifichem 2010
- Place of Presentation
  Hawaii, USA
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] Site-selective scission of double- stranded DNA by Ce(IV)/EDTA and only one mixed-base PNA.2010
- Author(s)
  Y.Aiba・Y.Hamano・A.Accetta・S.Sforza・R.Marchelli・R.Corradini・M.Komiyama
- Organizer
  2010 International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, Hawaii, USA(ポスター発表)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] 単一のPNA-peptide コンジュゲートを利用した位置選択的DNA切断2010
- Author(s)
  愛場雄一郎・濱野悠也・Accetta Alessandro・Sforza Stefano・Marchelli Rosangela・Corradini Roberto・小宮山眞
- Organizer
  第4回バイオ関連化学シンポジウム
- Place of Presentation
  大阪大学(ポスター発表)
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] 単一のPNA-peptideコンジュゲートを利用した位置選択的DNA 切断2010
- Author(s)
  愛場雄一郎・濱野悠也・Accetta Alessandro・Sforza Stefano・Marchelli Rosangela・Corradini Roberto・小宮山眞
- Organizer
  第25回生体機能関連化学シンポジウム「若手フォーラム」
- Place of Presentation
  大阪大学(ポスター発表)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] 単一のPNA-peptideコンジュゲートを利用した位置選択的DNA切断2010
- Author(s)
  ○愛場雄一郎・濱野悠也・A.Accetta・S.Sforza・R.Marchelli・R.Corradini・小宮山眞
- Organizer
  第25回生体機能関連化学シンポジウム
- Place of Presentation
  大阪大学
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] Incorporation of a flexible linker into pseudo-complementary PNA for the strict recognition of DNA.2010
- Author(s)
  Y.Aiba・Y.Nishiyama・M.Komiyama
- Organizer
  The 37th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  Yokohama, Japan(ポスター発表)
- Year and Date
  2010-11-10
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] Strict recognition of double-stranded DNA by chemically modified PNA(Peptide Nucleic Acid)2010
- Author(s)
  ○Y.Aiba, M.Komiyama
- Organizer
  Pacifichem 2010
- Place of Presentation
  Hawaii, USA
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22850004
[Presentation] リン酸系配位子による人工DNAカッターARCUTの高効率化2009
- Author(s)
  愛場雄一郎・濱野悠也・河邉明博・鈴木裕太・Tuomas Lonnberg・徐岩・須磨岡淳・小宮山眞
- Organizer
  第19回バイオ・高分子シンポジウム
- Place of Presentation
  東京大学
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-07J03030
[Presentation] ジスルフィド結合を導入したPNAによるDNAの認識とその制御2009
- Author(s)
  愛場雄一郎, 小宮山眞
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  日本大学
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-07J03030
[Presentation] Novel modification of Peptide Nucleic Acid(PNA)by functional linkers for versatile applications2009
- Author(s)
  愛場雄一郎・小宮山眞
- Organizer
  2nd Switzerland-Japan Biomolecular Chemistry Symposium 2009
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-07J03030
[Presentation] Novel functionalization of PNA by using linkers for versatile applications2009
- Author(s)
  Yuichiro Aiba, Makoto Komiyam
- Organizer
  U-Tokyo/Yonsei U GCOE Joint Symposium "Chemistry Innovation"
- Place of Presentation
  東京大学
- Year and Date
  2009-01-19
- Data Source
  KAKENHI-PROJECT-07J03030
[Presentation] リン酸系配位子による人工DNAカッターARCUTの高効率化2009
- Author(s)
  愛場雄一郎・小宮山眞
- Organizer
  The 6th International Symposium on Nucleic Acids Chemistry, 2009
- Place of Presentation
  Gifu, Japan
- Year and Date
  2009-09-28
- Data Source
  KAKENHI-PROJECT-07J03030
[Presentation] Introduction of linkers into PNA for versatile applications2008
- Author(s)
  Yuichiro Aiba, Makoto Komiyama
- Organizer
  Joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids and 35th International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  京都大学
- Year and Date
  2008-09-09
- Data Source
  KAKENHI-PROJECT-07J03030
[Presentation] ジスルフィド結合導入PNAによるインベージョンとその制御2008
- Author(s)
  愛場雄一郎, 須磨岡淳, 小宮山眞
- Organizer
  第3回バイオ関連化学合同シンポジウム2008
- Place of Presentation
  東京工業大学
- Year and Date
  2008-09-19
- Data Source
  KAKENHI-PROJECT-07J03030
[Presentation] リン酸系配位子導入によるDNA切断の効率化とその応用2008
- Author(s)
  愛場雄一郎
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  立教大学
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-07J03030
[Presentation] リン酸系配位子導入によるDNA位置選択的切断の高率化と遺伝子操作2008
- Author(s)
  愛場雄一郎, Tuomas Lonnberg, 鈴木裕太, 小宮山眞
- Organizer
  生体機能関連化学若手の会サマースクール
- Place of Presentation
  宮城県
- Year and Date
  2008-08-06
- Data Source
  KAKENHI-PROJECT-07J03030
[Presentation] Rapid site-selective hydrolysis of double-stranded DNA by use of Ce(IV)/EDTA and PNA bearing phosphate group2007
- Author(s)
  Yuichiro Aiba
- Organizer
  International Symposium Series of NanoBio Molecular Assemblies, Yonsei University-The University of Tokyo Joint Symposium
- Place of Presentation
  Yonsei University(韓国)
- Year and Date
  2007-09-07
- Data Source
  KAKENHI-PROJECT-07J03030
[Presentation] Ce(IV)/EDTAとpcPNAを用いた2本鎖DNAの位置選択的切断2007
- Author(s)
  愛場雄一郎
- Organizer
  東京大学生命科学研究ネットワークシンポジウム2007
- Place of Presentation
  東京大学
- Year and Date
  2007-09-15
- Data Source
  KAKENHI-PROJECT-07J03030
[Presentation] PNA-peptide conjugateの2重鎖DNA位置選択的切断への応用
- Author(s)
  愛場　雄一郎
- Organizer
  第60回高分子討論会
- Place of Presentation
  岡山大学　津島キャンパス（岡山県）
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] Ce(IV)/EDTA とペプチド核酸・ペプチドコンジュゲートによる位置選択的 DNA 切断
- Author(s)
  愛場　雄一郎
- Organizer
  第28回希土類討論会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] 細胞内応用を志向した人工DNAカッター（ARCUT）の開発
- Author(s)
  愛場　雄一郎
- Organizer
  第21回バイオ・高分子シンポジウム
- Place of Presentation
  東京大学先端科学技術研究センター（東京都）
- Data Source
  KAKENHI-PROJECT-22000007
[Presentation] 細胞内応用へ向けた人工DNAカッターARCUTの高機能化
- Author(s)
  愛場　雄一郎
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば国際会議場（茨城県）
- Data Source
  KAKENHI-PROJECT-22000007

1. KOMIYAMA Makoto (50133096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SUMAOKA Jun (10280934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. XU Yan (40506763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ITO Yasuhiro (50508108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HIGUCHI Maiko (30420235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SHIGI Narumi (00396780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. SHOJI Osami

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 小宮山真

# of Collaborated Projects: 0 results

# of Collaborated Products: 14 results

AIBA YUICHIRO 愛場 雄一郎

Aiba Yuichiro 愛場 雄一郎

AIBA Yuichiro 愛場 雄一郎

愛場 雄一郎 アイバ ユウイチロウ

Research Projects

Research Products

Co-Researchers

Development of PNA toward intracellular nucleic acid manipulationPrincipal Investigator

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Development of peptide nucleic acids recognizing double-stranded DNA with high efficiencyPrincipal Investigator

Principal Investigator

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DNA scission activity of Thermus thermophilus Argonaute with artificial nucleic acidsPrincipal Investigator

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Research Institution

Construction of stabilized PNA/DNA invasion complex for the analysis of higher-order structure of DNAPrincipal Investigator

Principal Investigator

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Creation of genome manipulation technology using super restriction enzyme

Principal Investigator

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セリウム触媒を利用した人工制限酵素の高機能化および遺伝子操作への応用Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] Recognition of mismatched sites in double-stranded DNA by a pair of partially noncomplementary peptide nucleic acids2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sequence-Specific Recognition of Double-Stranded DNA by Using Only PNAs in Parallel with Natural Nucleobases2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sequence-Specific Recognition of Double-Stranded DNA by Peptide Nucleic Acid Forming Double-Duplex Invasion Complex2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Investigation of the Characteristics of NLS-PNA: Influence of NLS Location on Invasion Efficiency2020

Author(s)

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DOI

Data Source

[Journal Article] Cationic Guanine: Positively Charged Nucleobase with Improved DNA Affinity Inhibits Self-Duplex Formation2019

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DOI

Data Source

[Journal Article] Promotion of double-duplex invasion of peptide nucleic acid through conjugation with nuclear localization signal peptide2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Affinity-isolation of desired restriction fragment from human genome using double-duplex invasion of biotin-bound pseudo-complementary PNA.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] PNA-NLS conjugates as single-molecular activators of target sites in double-stranded DNA for site-selective scission2013

AIBA YUICHIRO 愛場雄一郎

Aiba Yuichiro 愛場雄一郎

AIBA Yuichiro 愛場雄一郎

愛場雄一郎アイバユウイチロウ