Yoshino Hironori 吉野浩教

… Alternative Names

YOSHINO Hironori 吉野浩教

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Researcher Number	10583734
Other IDs
Affiliation (Current)	2023: 弘前大学, 保健学研究科, 助教
Affiliation (based on the past Project Information) *help	2023: 弘前大学, 保健学研究科, 助教 2011 – 2021: 弘前大学, 保健学研究科, 助教 2014 – 2016: 弘前大学, 大学院保健学研究科, 助教 2010 – 2012: 弘前大学, 大学院・保健学研究科, 助教
Review Section/Research Field	Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related Except Principal Investigator Radiation science / Laboratory medicine / Fundamental nursing / Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator 放射線 / 自然免疫 / 放射線治療 / パターン認識受容体 / RIG-I様受容体 / 放射線抵抗性 / 細胞死 / アポトーシス / 樹状細胞 / レドックス制御 … More / Toll様受容体 / 単球 / マクロファージ / poly(I:C) / 病原体関連分子 / RIG様受容体 / JNK / ダメージ関連分子パターン / 放射線曝露細胞由来馴化培地 / Nrf2 / 細胞移動能 / p53 / DAMPs / 抗酸化ストレス / RIG-I / ミトコンドリア / 放射線増感 / Fas / DAP3 / Fasリガンド / IFN-β / cGAS / 細胞老化 / 分裂期崩壊 / 放射線感受性 / 細胞老化随伴分泌現象 … More Except Principal Investigator 放射線 / 急性放射線症候群 / 被ばく医療 / 造血幹細胞 / 放射線治療 / 放射線防護剤 / エキソソーム / 被ばくマーカー / 遺伝子 / 個体差 / アスコルビン酸 / 癌 / 細胞死 / 併用療法 / ヌードマウス / 腫瘍移植 / 放射線生物学 / 放射縁抵抗性 / 医薬品 / 全身照射 / romiprostim / TPO受容作動薬 / 急性放射性症候群 / TPO受容体作動薬 / 放射線被ばく / 血清中microRNA / バイオマーカー / microRNA / 血清 / 被ばくバイオマーカー / RNA / 放射線看護 / 教育 / 看護教育 / ４－メチルウンベリフェロン / 転移 / サイトカイン / 抗癌作用 / ４-メチルウンベリフェロン / 浸潤 / 4-メチルウンベリフェロン / マイクロRNA / 染色体異常解析 / miRNA / 薬物療法 / トロンボポエチン受容体作動薬 / 骨髄死 / 多臓器不全 / 間葉系幹細胞 / トロンボポエチン受容体 / 放射線緩和剤 / 相分離 / スーパーエンハンサー / DNA損傷 / DNA修復 Less

The role of phase-separation upon radiation-induced DNA damages
- Principal Investigator
  
  羽澤勝治
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kanazawa University
パターン認識受容体cGASが介在する放射線応答制御の解明と癌放射線治療への応用Principal Investigator
- Principal Investigator
  
  吉野浩教
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hirosaki University
The mechanisms by which RIG-I-like receptor pathways modulate cellular radiation responsePrincipal Investigator
- Principal Investigator
  
  Yoshino Hironori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hirosaki University
Development of the optimal medication for individuals exposed to lethal radiation
- Principal Investigator
  
  Kashiwakura Ikuo
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University
Effects of DAMPs from cancer cells exposed to radiation on the properties of cancer cellsPrincipal Investigator
- Principal Investigator
  
  Yoshino Hironori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University
Creation of an Educational Program on Radiation Protection and Safety Management Required in Nursing and Development of Educational Tools
- Principal Investigator
  
  NOTO YUKA
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fundamental nursing
- Research Institution
  Hirosaki University
Application of exosomal molecules as exposure dose assessment markers
- Principal Investigator
  
  KASHIWAKURA IKUO
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University
Life-saving effect and mechanism of action of thrombopoietin receptor agonist in radiation-exposed individuals
- Principal Investigator
  
  KASHIWAKURA IKUO
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University
The development of novel internal radiation dosimetry using circulating exosomal RNAs into body fluids
- Principal Investigator
  
  CHIBA Mitsuru
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Hirosaki University
Enhancement of radiation therapy for cancer treatment by focusing on pattern recognition receptorsPrincipal Investigator
- Principal Investigator
  
  YOSHINO Hironori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University
Protective effects of a combination of multiple pharmaceutical drugs on the survival of mice exposed to lethal ionizing radiation
- Principal Investigator
  
  KASHIWAKURA Ikuo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University
The study of anti-tumor with anti-metastasis under combination of 4-methylumbelliferone on X-irradiation against cancer cell
- Principal Investigator
  
  Hosokawa Yoichiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University
Effects of ionizing radiation on the pattern recognition receptors.Principal Investigator
- Principal Investigator
  
  YOSHINO Hironori
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University
The identification of factor (s) which regulate individual radiosensitivity of human hematopoietic stem/progenitor cells and its application
- Principal Investigator
  
  KASHIWAKURA Ikuo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University
The study of new radiation therapy combined with high concentration ascorbic acid as to achieve high tumor local control rate
- Principal Investigator
  
  HOSOKAWA Yoichiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Hirosaki University

[Journal Article] Discovery of a Novel Small-molecule Interleukin-6 Inhibitor ThroughVirtual Screening Using Artificial Intelligence2022
- Author(s)
  Sato Yoshiaki、Kashiwakura Ikuo、Yamaguchi Masaru、Yoshino Hironori、Tanaka Takeshi、Ikeda Ken、Ye Zhengmao、Komatsu Hirotsugu、Matsuzaki Takao、Hosoda Masato
- Journal Title
  
  Medicinal Chemistry
  
  Volume: 18 Issue: 6 Pages: 694-700
- DOI
  10.2174/1573406418666211116144243
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07691, KAKENHI-PROJECT-21K17887
[Journal Article] Cytotoxic activity of a unique monomeric heterogeneous two-coordinate ligand monovalent gold complex with tiopronin and a heterocyclic mercapto-tetrazole compound2021
- Author(s)
  Sano Naoyuki、Yoshino Hironori、Sato Yoshiaki、Honma Hideo、Cordonier Christopher E. J.、Kashiwakura Ikuo
- Journal Title
  
  Current Medicinal Chemistry
  
  Volume: 28 Issue: 22 Pages: 3973-3982
- DOI
  10.2174/0929867328666211018094206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07691
[Journal Article] DAP3 Is Involved in Modulation of Cellular Radiation Response by RIG-I-Like Receptor Agonist in Human Lung Adenocarcinoma Cells2021
- Author(s)
  Sato Yoshiaki、Yoshino Hironori、Kashiwakura Ikuo、Tsuruga Eichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 1 Pages: 420-420
- DOI
  10.3390/ijms22010420
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07623
[Journal Article] The Effect of High-Dose-Rate Pulsed Radiation on the Survival of Clinically Relevant Radioresistant Cells2021
- Author(s)
  Terashima Shingo、Yoshino Hironori、Kuwahara Yoshikazu、Sakuraba Hiro、Hosokawa Yoichiro
- Journal Title
  
  Life
  
  Volume: 11 Issue: 12 Pages: 1295-1295
- DOI
  10.3390/life11121295
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12326, KAKENHI-PROJECT-18K15537, KAKENHI-PROJECT-19K08141, KAKENHI-PROJECT-21K07691
[Journal Article] Matrix Metalloproteinase-2 Activated by Ultraviolet-B Degrades Human Ciliary Zonules <i>In Vitro</i>2021
- Author(s)
  Yuki Shiroto, Ryo saga, yoichiro Hosokawa, keitaro Isokawa, Eichi Tsuruga
- Journal Title
  
  ACTA HISTOCHEMICA ET CYTOCHEMICA
  
  Volume: 54 Issue: 1 Pages: 1-9
- DOI
  10.1267/ahc.20-00021
- NAID
  130007991354
- ISSN
  0044-5991, 1347-5800
- Year and Date
  2021-02-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08141, KAKENHI-PROJECT-18K07623
[Journal Article] Not Only Hypoxia- but Radiation-Induced Epithelial-Mesenchymal Transition Is Modulated by Hypoxia-Inducible Factor 1 in A549 Lung Cancer Cells.2021
- Author(s)
  Sato M, Hirose K, Ichise K, Yoshino H, Harada T, Hatayama Y, Kawaguchi H, Tanaka M, Fujioka I, Takai Y, Aoki M.
- Journal Title
  
  Folia Biol (Praha)
  
  Volume: 67 Pages: 62-69
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07691
[Journal Article] Effects and Related Mechanisms of the Senolytic Agent ABT-263 on the Survival of Irradiated A549 and Ca9-22 Cancer Cells2021
- Author(s)
  Sato Kota、Iwasaki Soichiro、Yoshino Hironori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 24 Pages: 13233-13233
- DOI
  10.3390/ijms222413233
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07691
[Journal Article] KPNB1 Inhibitor Importazole Reduces Ionizing Radiation-Increased Cell Surface PD-L1 Expression by Modulating Expression and Nuclear Import of IRF12021
- Author(s)
  Yoshino Hironori、Sato Yoshiaki、Nakano Manabu
- Journal Title
  
  Current Issues in Molecular Biology
  
  Volume: 43 Issue: 1 Pages: 153-162
- DOI
  10.3390/cimb43010013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07691
[Journal Article] Fas Ligand Enhances Apoptosis of Human Lung Cancer Cells Cotreated with RIG-I-Like Receptor Agonist and Radiation2020
- Author(s)
  Sato Yoshiaki、Yoshino Hironori、Tsuruga Eichi、Kashiwakura Ikuo
- Journal Title
  
  Current Cancer Drug Targets
  
  Volume: 20 Issue: 5 Pages: 372-381
- DOI
  10.2174/1568009620666200115161717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07623
[Journal Article] Karyopherin-β1 Regulates Radioresistance and Radiation-Increased Programmed Death-Ligand 1 Expression in Human Head and Neck Squamous Cell Carcinoma Cell Lines2020
- Author(s)
  Hazawa M, Yoshino H, Nakagawa Y, Shimizume R, Nitta K, Sato Y, Sato M, Wong RW, Kashiwakura I
- Journal Title
  
  Cancers
  
  Volume: 12(4) Issue: 4 Pages: 908-908
- DOI
  10.3390/cancers12040908
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08655, KAKENHI-PROJECT-17K16332, KAKENHI-PROJECT-18K07623
[Journal Article] Effects of irradiated cell conditioned medium on the response of human lung cancer cells to anticancer treatment in vitro2019
- Author(s)
  Yoshino Hironori、Nawamaki Mikoto、Murakami Kanna、Kashiwakura Ikuo
- Journal Title
  
  World Academy of Sciences Journal
  
  Volume: 1 Pages: 92-97
- DOI
  10.3892/wasj.2019.11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07623
[Journal Article] Dose-Dependent Increase of Nrf2 Target Gene Expression in Mice Exposed to Ionizing Radiation2019
- Author(s)
  Miura Shuta、Yamaguchi Masaru、Yoshino Hironori、Nakai Yuji、Kashiwakura Ikuo
- Journal Title
  
  Radiation Research
  
  Volume: 191 Issue: 2 Pages: 176-188
- DOI
  10.1667/rr15203.1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07726, KAKENHI-PROJECT-18K18190, KAKENHI-PROJECT-16H02667
[Journal Article] Disease-specific alteration of karyopherin-α subtype establishes feed-forward oncogenic signaling in head and neck squamous cell carcinoma2019
- Author(s)
  Hazawa Masaharu、Sakai Kie、Kobayashi Akiko、Yoshino Hironori、Iga Yoshihiro、Iwashima Yuki、Lim Kee Sing、Chih-Cheng Voon Dominic、Jiang Yan-Yi、Horike Shin-ichi、Lin De-Chen、Wong Richard W.
- Journal Title
  
  Oncogene
  
  Volume: 39 Issue: 10 Pages: 2212-2223
- DOI
  10.1038/s41388-019-1137-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07623, KAKENHI-PROJECT-19K07398, KAKENHI-PROJECT-17K08655, KAKENHI-PROJECT-17K16332
[Journal Article] 制がんにおけるRetinoic acid-inducible gene-I 様受容体の役割2019
- Author(s)
  吉野　浩教
- Journal Title
  
  放射線生物研究
  
  Volume: 54 Pages: 1-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07623
[Journal Article] Involvement of caspase-8 in apoptosis enhancement by cotreatment with retinoic acid-inducible gene-I-like receptor agonist and ionizing radiation in human non-small cell lung cancer2018
- Author(s)
  YOSHIAKI SATO, HIRONORI YOSHINO, YUKA KAZAMA and IKUO KASHIWAKURA
- Journal Title
  
  MOLECULAR MEDICINE REPORTS
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09985
[Journal Article] Effects of Nrf2 knockdown on the properties of irradiated cell conditioned medium from A549 human lung cancer cells.2018
- Author(s)
  H. Yoshino, K. Murakami, M. Nawamaki, I. Kashiwakura.
- Journal Title
  
  Biomed Rep
  
  Volume: 印刷中 Pages: 461-465
- DOI
  10.3892/br.2018.1073
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02667, KAKENHI-PROJECT-15K09985, KAKENHI-PROJECT-18K07623
[Journal Article] Synergistic effects of retinoic acid-inducible gene-I-like receptors activations and ionizing radiation on cytotoxicity against human non-small lung cancer cells.2018
- Author(s)
  H. Yoshino, M. Iwabuchi, Y. Kazama, M. Furukawa, I. Kashiwakura.
- Journal Title
  
  Oncol Lett
  
  Volume: 15 Pages: 4697-4705
- DOI
  10.3892/ol.2018.7867
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02667, KAKENHI-PROJECT-15K09985, KAKENHI-PROJECT-18K07623
[Journal Article] Relationship between the Regulation of Caspase-8-Mediated Apoptosis and Radioresistance in Human THP-1-Derived Macrophages2018
- Author(s)
  Yoshino Hironori、Konno Haruka、Ogura Koya、Sato Yoshiaki、Kashiwakura Ikuo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 10 Pages: 3154-3154
- DOI
  10.3390/ijms19103154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07623
[Journal Article] Involvement of caspase-8 in apoptosis enhancement by cotreatment with retinoic acid-inducible gene-I-like receptor agonist and ionizing radiation in human non-small cell lung cancer2018
- Author(s)
  Sato Yoshiaki、Yoshino Hironori、Kazama Yuka、Kashiwakura Ikuo
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 18 Pages: 5286-5294
- DOI
  10.3892/mmr.2018.9536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07623
[Journal Article] Involvement of reactive oxygen species in ionizing radiation-induced upregulation of cell surface Toll-like receptor 2 and 4 expressions in human monocytic cell.2017
- Author(s)
  Yoshino H, Kashiwakura I
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 印刷中 Issue: 5 Pages: 1-10
- DOI
  10.1093/jrr/rrx011
- NAID
  120006559353
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09985, KAKENHI-PROJECT-16H02667
[Journal Article] Effects of endoplasmic reticulum stress on apoptosis induction in radioresistant macrophages.2017
- Author(s)
  Yoshino H, Kumai Y, Kashiwakura.
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 15(5) Issue: 5 Pages: 2867-2872
- DOI
  10.3892/mmr.2017.6298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02667, KAKENHI-PROJECT-15K15443, KAKENHI-PROJECT-15K09985
[Journal Article] p53-independent structure-activity relationships of 3-ring mesogenic compounds’ activity as cytotoxic effects against human non-small cell lung cancer lines2016
- Author(s)
  Fukushi S, Yoshino H, Yoshizawa A, Kashiwakura I
- Journal Title
  
  BMC Cancer
  
  Volume: 16 Issue: 1 Pages: 521-521
- DOI
  10.1186/s12885-016-2585-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09985
[Journal Article] Mitigative Effects of a Combination of Multiple Pharmaceutical Drugs on the Survival of Mice Exposed to Lethal Ionizing Radiation.2015
- Author(s)
  T. Hirouchi, K. Ito, M. Nakano, S. Monzen, H. Yoshino, M. Chiba, M. Hazawa, A. Nakano, J. Ishikawa, M. Yamaguchi, K. Tanaka, I. Kashiwakura.
- Journal Title
  
  Current Pharmaceutical Biotechnology
  
  Volume: 17(2) Pages: 190-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15443
[Journal Article] Effects of X-ray irradiation in combination with ascorbic acid on tumor control.2015
- Author(s)
  Hosokawa Y, Monzen S, Yoshino H, Terashima S, Nakano M, Toshima K, Saga R, Kashiwakura I
- Journal Title
  
  Mol Med Rep.
  
  Volume: 12 Pages: 5449-5454
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591831
[Journal Article] Effects of ionizing radiation on retinoic acid-inducible gene-I-like receptors.2015
- Author(s)
  Yoshino H, Saitoh T, Kozakai M, Kashiwakura I.
- Journal Title
  
  Biomedical Reports
  
  Volume: 3 Pages: 59-62
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25861053
[Journal Article] Effects of ionizing radiation on retinoic acid-inducible gene-I-like receptors2015
- Author(s)
  H. Yoshino, T. Saitoh, M. Kozakai, I. Kashiwakura
- Journal Title
  
  Biomedical reports
  
  Volume: 3 (1) Issue: 1 Pages: 59-62
- DOI
  10.3892/br.2014.377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293256
[Journal Article] The report of the 1st Educational Symposium on Radiation and Health by Young Scientists (ESRAH2014).2015
- Author(s)
  Masahiro Hosoda, Hironori Yoshino, Masaru Yamaguchi, Takakiyo Tsujiguchi, Mitsuru Chiba, Toshiya Nakamura.
- Journal Title
  
  Japanese Journal of Health Physics
  
  Volume: 50
- NAID
  130005113883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670264
[Journal Article] Mitigative Effects of a Combination of Multiple Pharmaceutical Drugs on the Survival of Mice Exposed to Lethal Ionizing Radiation.2015
- Author(s)
  T. Hirouchi, K. Ito, M. Nakano, S. Monzen, H. Yoshino, M. Chiba, M. Hazawa, A. Nakano, J. Ishikawa, M. Yamaguchi, K. Tanaka, I. Kashiwakura.
- Journal Title
  
  Current Pharmaceutical Biotechnology
  
  Volume: 17(2) Pages: 190-199
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293256
[Journal Article] 急性放射線症候群およびがん放射線治療におけるToll 様受容体の関与2015
- Author(s)
  吉野浩教
- Journal Title
  
  放射線生物研究
  
  Volume: 50 Pages: 255-268
- NAID
  40020691935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09985
[Journal Article] Effects of ionizing radiation on differentiation of murine bone marrow cells into mast cells.2015
- Author(s)
  S. Murakami , H. Yoshino , J. Ishikawa, M. Yamaguchi , T. Tsujiguchi , A. Nishiyama , K. Yokoyama , I. Kashiwakura .
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 56(6) Issue: 6 Pages: 865-871
- DOI
  10.1093/jrr/rrv061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15443, KAKENHI-PROJECT-25293256
[Journal Article] Long-lasting radioprotective effects of a combination of pharmaceutical drugs on the survival of mice exposed to lethal ionizing radiation2014
- Author(s)
  M. Yamaguchi, T. Hirouchi, M. Nakano, S. Monzen, H. Yoshino, M. Chiba, J. Ishikawa, A. Nishiyama, S. Murakami, K. Ito and I. Kashiwakura
- Journal Title
  
  Radiat. Emerg. Med.
  
  Volume: 3(1) Pages: 50-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659553
[Journal Article] Long-lasting radioprotective effects of a combination of pharmaceutical drugs on the survival of mice exposed to lethal ionizing radiation2014
- Author(s)
  M. Yamaguchi, T. Hirouchi, M. Nakano, S. Monzen, H. Yoshino, M. Chiba, J. Ishikawa, A. Nishiyama, S. Murakami, K. Ito and and I. Kashiwakura
- Journal Title
  
  Radiation Emergency Medicine
  
  Volume: 3 Pages: 50-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659553
[Journal Article] Effects of Liquid-Crystallinity on Anticancer Activity of Benzoate Derivatives Possessing a Terminal Hydroxyl Group2014
- Author(s)
  Yukako Fukushi, Hironori Yoshino, Junya Ishikawa, Masanobu Sagisaka, Ikuo Kashiwakura, Atsushi Yoshizawa
- Journal Title
  
  Liquid Crystals
  
  Volume: 41 Issue: 12 Pages: 1873-1878
- DOI
  10.1080/02678292.2014.956350
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25107702, KAKENHI-PROJECT-25861053
[Journal Article] 4-methylumbelliferone’s addition against human fibrosarucoma cells and the effect of radiation concomitant use2014
- Author(s)
  Ryo Saga, Yoichiro Hosokawa, Hironori Yoshino, Shingo Terashima, Toshiya Nakamura
- Journal Title
  
  The Proceedings of the 5ｔｈ　International Symposium on Radiation Emergency Medicine at Hirosaki University
  
  Volume: 4 Pages: 36-38
- Data Source
  KAKENHI-PROJECT-24591831
[Journal Article] Long-lasting radioprotective effects of a combination of pharmaceutical drugs on the survival of mice exposed to lethal ionizing radiation2014
- Author(s)
  M. Yamaguchi, T. Hirouchi, M. Nakano, S. Monzen, H. Yoshino, M. Chiba, J. Ishikawa, A. Nishiyama, S. Murakami, K. Ito and and I. Kashiwakura.
- Journal Title
  
  Radiat Emerg Med
  
  Volume: 3 Pages: 50-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293256
[Journal Article] Synthesis and Anticancer Properties of Phenyl Benzoate derivatives possessing a terminal hydroxyl group2014
- Author(s)
  Yukako Fukushi, Hironori Yoshino, Junya Ishikawa, Masanobu Sagisaka, Ikuo Kashiwakura, Atsushi Yoshizawa
- Journal Title
  
  J. Mater. Chem. B
  
  Volume: 2 Issue: 10 Pages: 1335-1343
- DOI
  10.1039/c3tb21736a
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25107702, KAKENHI-PROJECT-25861053
[Journal Article] Ionizing radiation affects the expression of Toll-like receptors 2 and 4 in human monocytic cells through c-Jun N-terminal kinase activation2014
- Author(s)
  H. Yoshino, K. Chiba, T. Saitoh, I. Kashiwakura
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 55 (5) Issue: 5 Pages: 876-884
- DOI
  10.1093/jrr/rru040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293256, KAKENHI-PROJECT-25861053
[Journal Article] A liquid crystal-related compound induces cell cycle arrest at the G2/M phase and appotosis in the A549 human non-small cell lung cancer cell line2013
- Author(s)
  Wakasaya T, Yoshino H, Fukushi Y,Yoshizawa A, Kashiwakura I
- Journal Title
  
  International Journal of Oncology
  
  Volume: 42 Pages: 1205-1211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791383
[Journal Article] Effect of ascorbic acid and X-irradiation on HL-60 human leukemia cells: the kinetics of reactive oxygen species.2013
- Author(s)
  Terashima S, Hosokawa Y, Yoshino H, Yamaguchi M, Nakamura T.
- Journal Title
  
  Oncol Rep.
  
  Volume: 30(6) Issue: 6 Pages: 2653-2658
- DOI
  10.3892/or.2013.2758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591831, KAKENHI-PROJECT-25861053
[Journal Article] Impairmentof mature dendritic cells derived from X-irradiated human monocytes depends on the type of maturation stimulus used2012
- Author(s)
  Yoshino H, Kashiwakura I
- Journal Title
  
  Radiation Research
  
  Volume: 178 Pages: 280-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791383
[Journal Article] Impairment of mature dendritic clls derived from X-irradiated human monocytes depends on the type of maturation stimulus used.2012
- Author(s)
  Hironori Yoshino, et al.
- Journal Title
  
  Radiation Research
  
  Volume: 178 Issue: 4 Pages: 280-288
- DOI
  10.1667/rr2997.1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791383
[Journal Article] Response of the Nrf2 protection system in human monocytic cells after ionising irradiation2012
- Author(s)
  Yoshino H, Kiminarita T, Matsushita Y,Kashiwakura I
- Journal Title
  
  Radiation Protection Dosimetry
  
  Volume: 152 Pages: 104-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791383
[Journal Article] Regulation of DNA damage response and cell cycle in radiation-resistant HL60 myeloid leukemia cells2012
- Author(s)
  Hazawa M, Hosokawa Y, Monzen S, Yoshino H, Kashiwakura I
- Journal Title
  
  PLoS One
  
  Volume: 6(11)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591603
[Journal Article] Response of the Nrf2 protection system in human monocytic cells after ionising iIrradiation.2012
- Author(s)
  Hironori Yoshino, et al.
- Journal Title
  
  Radiation Protection Dosimetry
  
  Volume: 152 Issue: 1-3 Pages: 104-108
- DOI
  10.1093/rpd/ncs201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791383
[Journal Article] Individual radiation exposure dose due to support activities at safe shelters in Fukushima Prefecture2011
- Author(s)
  S. Monzen, M. Hosoda, M. Osanai, H. Yoshino, S. Tokonami, Y. Hosokawa, M.A. Yoshida, M. Yamada, Y. Asari, K. Satoh and I. Kashiwakura
- Journal Title
  
  PLos One
  
  Volume: 6(11)
- Data Source
  KAKENHI-PROJECT-21390336
[Journal Article] Terminal maturation of megakaryocytes and platelet production derived from hematopoietic stem cells irradiated to heavy-ion beams2011
- Author(s)
  S. Monzen, K. Takahashi, H. Yoshino, K. Kasai-Eguchi and I. Kashiwakura
- Journal Title
  
  Radiat Res
  
  Volume: 176(1) Pages: 8-16
- Data Source
  KAKENHI-PROJECT-21390336
[Journal Article] Involvement of intracellular reactive oxygen species and mitochondria in the radiosensitivity of human hematopoietic stem cells2011
- Author(s)
  Y. Kaneyuki, H. Yoshino and I. Kashiwakura
- Journal Title
  
  J Radiat Res
  
  Volume: 53(1) Pages: 145-50
- NAID
  10030023889
- Data Source
  KAKENHI-PROJECT-21390336
[Journal Article] Inductive potential of recombinant human granulocyte colony-stimulating factor to mature neutrophils from X-irradiated human peripheral blood hematopoietic progenitor cells2009
- Author(s)
  T. Katsumori, H. Yoshino, K. Takahashi and I. Kashiwakura
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 32(11) Pages: 1849-1853
- NAID
  130000116956
- Data Source
  KAKENHI-PROJECT-21390336
[Journal Article] Heavy ion beam irradiation regulates the mRNA expression in megakaryocytopoiesis from human hematopoietic stem/progenitor cells2009
- Author(s)
  S. Monzen, H. Yoshino, K. Takahashi and I. Kashiwakura
- Journal Title
  
  J Radiat Res
  
  Volume: 50(5) Pages: 477-486
- NAID
  10025912849
- Data Source
  KAKENHI-PROJECT-21390336
[Journal Article] Mitochondrial superoxide production and redox status in human monocytic cells after ionizing irradiation
- Author(s)
  Yoshino H, Kiminarita T, Matsushita Y, Kashiwakura I
- Journal Title
  
  Radiation Emergency Medicine
  
  Volume: 印刷中
- NAID
  40019745067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791383
[Patent] 放射線被ばく治療剤及び放射線被ばく治療方法2012
- Inventor(s)
  柏倉幾郎,伊藤巧一,中野学,門前暁,千葉満,吉野浩教,廣内篤久
- Industrial Property Rights Holder
  弘前大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-250880
- Filing Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-24659553
[Patent] 放射線被ばく治療剤及び放射線被ばく治療方法2012
- Inventor(s)
  柏倉幾郎、伊藤巧一、中野学、門前暁、千葉満、吉野浩教、廣内篤久
- Industrial Property Rights Holder
  弘前大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-250880
- Filing Date
  2012-11-15
- Data Source
  KAKENHI-PROJECT-24659553
[Presentation] 扁平上皮癌細胞の放射線応答における核輸送因子KPNB1の役割2021
- Author(s)
  吉野浩教
- Organizer
  金沢大学　新学術創成研究機構　異分野融合セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] ヒト肺腺癌細胞A549の放射線照射後の細胞周期動態におけるミトコンドリアリボソームタンパク質DAP3の役割2021
- Author(s)
  佐藤嘉晃，吉野浩教，敦賀英知
- Organizer
  第58回日本放射線腫瘍学会生物部会学術大会
- Data Source
  KAKENHI-PROJECT-21K07691
[Presentation] Karyopherin-β1 regulates radioresistance in head and neck squamous cell carcinoma cell lines2021
- Author(s)
  Masaharu Hazawa, Richard Wong, Ikuo kashiwakura, Hironori Yoshino
- Organizer
  日本放射線影響学会　第64回大会
- Data Source
  KAKENHI-PROJECT-21K07691
[Presentation] Roles of cGAS in cellular radiation responses of human head and neck squamous cell carcinoma cells2021
- Author(s)
  Taichi Nyui, Hironori Yoshino, Eichi Tsuruga
- Organizer
  日本放射線影響学会　第64回大会
- Data Source
  KAKENHI-PROJECT-21K07691
[Presentation] Cell cycle regulation by mitochondrial ribosome protein death-associated protein 3 in human lung adenocarcinoma cells exposed to ionizing radiation2021
- Author(s)
  Yoshiaki Sato, Hironori Yoshino, Eichi Tsuruga
- Organizer
  日本放射線影響学会　第64回大会
- Data Source
  KAKENHI-PROJECT-21K07691
[Presentation] Capabilities of dosimetry laboratories in Japan in response to large-scale radiation accidents2021
- Author(s)
  Tomisato Miura, Munehiko Kowatari, Kanya Hamasaki, Yu Abe, Hironori Yoshino
- Organizer
  日本放射線影響学会　第64回大会
- Data Source
  KAKENHI-PROJECT-21K07691
[Presentation] Investigations and recommendations on the assessment and estimation of radiation doses2021
- Author(s)
  Seiji Kodama, Junya Kobayashi, Hiroshi Yasuda, Tomisato Miura, Kento Nagata, Hironori Yoshino
- Organizer
  日本放射線影響学会　第64回大会
- Data Source
  KAKENHI-PROJECT-21K07691
[Presentation] Effect of Fas ligand to enhance apoptosis of human lung cancer cells cotreated with retinoic acid-inducible gene-I-like receptor agonist and X-ray irradiation.2020
- Author(s)
  Sato Y, Yoshino H, Tsuruga E, Kashiwakura I.
- Organizer
  The 3rd Workshop on Radiation Research and Its Related Issue 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] Death-associated protein 3 is involved in radioresistance of human lung adenocarcinoma cell lines2020
- Author(s)
  Sato Y, Yoshino H, Tsuruga E．
- Organizer
  日本放射線影響学会　第63回大会
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] Disease-specific alteration of karyopherin-α subtype establishes feed-forward oncogenic signaling in squamous cell carcinoma2019
- Author(s)
  羽澤勝治，酒井貴恵，吉野浩教，小林亜希子，Richard W Wong．
- Organizer
  第48回制癌シンポジウム・第57回生物部会学術大会
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] The underlying mechanisms of synergistic antitumor effects by cotreatment with retinoic acid-inducible gene-I-like receptor agonist and ionizing radiation.2019
- Author(s)
  Sato Yoshiaki, Yoshino Hironori, Kashiwakura Ikuo.
- Organizer
  16th International Congress of Radiation Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] In vitro radiosensitization effect of importin-β1 inhibitor in the human head and neck squamous cell carcinoma.2019
- Author(s)
  Yoshino Hironori, Nakagawa Yuta, Nitta Keisuke, Kashiwakura Ikuo.
- Organizer
  16th International Congress of Radiation Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] RIG-I様受容体刺激因子によるX線誘発細胞死増強機構の探索2019
- Author(s)
  佐藤嘉晃，吉野浩教，柏倉幾郎．
- Organizer
  第72回　日本酸化ストレス学会
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] ヒト単球系細胞THP1由来マクロファージにおける放射線抵抗性獲得とcaspase-8介在性アポトーシス制御との関連2019
- Author(s)
  吉野浩教，今埜遼香，小倉巧也，佐藤嘉晃，柏倉幾郎．
- Organizer
  令和元年度若手放射線生物学研究会専門研究会
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] RIG-I様受容体刺激因子とX線併用による抗腫瘍効果増強機構の探索2019
- Author(s)
  佐藤嘉晃，吉野浩教，柏倉幾郎．
- Organizer
  第48回制癌シンポジウム・第57回生物部会学術大会
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] Relationship between the regulation of caspase-8-mediated apoptosis and radioresistance in human THP1-derived macrophages2019
- Author(s)
  Yoshino Hironori
- Organizer
  2019 KIRAMS-Hirosaki University Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] Cotreatment with retinoic acid-inducible gene-I-like receptor agonist and ionizing radiation effectively induces apoptosis through caspase-8 mediated apoptotic pathway in human non-small cell lung cancer A5492018
- Author(s)
  Y. Sato, H. Yoshino, Y. Kazama and I. Kashiwakura
- Organizer
  The 5th Educational Symposium on Radiation and Health by young scientists (ESRAH2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02667
[Presentation] IONIZING RADIATION ENHANCES SYNTHETIC DOUBLE-STANDARD RNA-INDUCED APOPTOSIS IN HUMAN LUNG CANCER CELLS THROUGH CASPASE-8 ACTIVATION.2018
- Author(s)
  Sato Yoshiaki, Yoshino Hironori, Kazama Yuka, Kashiwakura Ikuo
- Organizer
  9th International Conference on High Level Environmental Radiation Areas
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] RIG-I様受容体刺激因子と放射線の併用によるヒト肺癌細胞に対する抗癌効果2018
- Author(s)
  吉野　浩教，岩淵　美憂，風間　祐佳，古川真帆，柏倉　幾郎
- Organizer
  平成30年度若手放射線生物学研究会専門研究会
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] Ionizing radiation enhances double-Stranded RNA-induced apoptosis in human lung epithelial cells through Caspase-8 activation2018
- Author(s)
  Y. Sato, H. Yoshino, Y. Kazama and I. Kashiwakura
- Organizer
  9th International Conference on High Levels of Environmental Radiation Areas (ICHLERA) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02667
[Presentation] 看護職に必要な「放射線防護・安全管理」に関する知識を学習するための教育ツールの提案2018
- Author(s)
  野戸結花，漆坂真弓，北島麻衣子，吉野浩教
- Organizer
  第7回日本放射線看護学会学術集会
- Data Source
  KAKENHI-PROJECT-15K11544
[Presentation] 放射線ばく露個体におけるKeap1-Nrf2系生体防御遺伝子発現解析2018
- Author(s)
  三浦柊太，山口平，吉野浩教，中井雄治，柏倉幾郎
- Organizer
  日本放射線腫瘍学会第56回生物部会学術大会
- Data Source
  KAKENHI-PROJECT-16H02667
[Presentation] Cotreatment with retinoic acid-inducible gene-I-like receptor agonist and ionizing radiation effectively induces apoptosis through caspase-8 mediated apoptotic pathway in human non-small cell lung cancer A5492018
- Author(s)
  Sato Yoshiaki, Yoshino Hironori, Kazama Yuka, Kashiwakura Ikuo
- Organizer
  The 5th Educational Symposium on RADIATION AND HEALTH by Young Scientists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] パターン認識受容体に及ぼす放射線の影響解明と癌放射線治療への応用2018
- Author(s)
  吉野　浩教
- Organizer
  日本放射線影響学会　第61回大会
- Data Source
  KAKENHI-PROJECT-18K07623
[Presentation] 放射線誘発Toll様受容体2及び4の細胞表面発現増強における活性酸素種の関与2017
- Author(s)
  吉野浩教，柏倉幾郎
- Organizer
  平成29年度若手放射線生物学研究会専門研究会
- Data Source
  KAKENHI-PROJECT-15K09985
[Presentation] 眼球毛様体小体の紫外線照射による影響2017
- Author(s)
  白戸佑貴，吉野浩教，寺島真悟，細川洋一郎，敦賀英知
- Organizer
  日本放射線影響学会　第60回大会
- Data Source
  KAKENHI-PROJECT-15K09985
[Presentation] ヒト単球系細胞の細胞分化に伴う放射線抵抗性獲得とCASAPSE-8の発現制御の関連.2017
- Author(s)
  吉野浩教, 今埜遼香, 小倉巧也, 柏倉幾郎.
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-16H02667
[Presentation] ヒト単球系細胞の細胞分化に伴う放射線抵抗性獲得とcasapse-8の発現制御の関連2017
- Author(s)
  吉野浩教，今埜遼香，小倉巧也，柏倉幾郎
- Organizer
  日本放射線影響学会　第60回大会
- Data Source
  KAKENHI-PROJECT-15K09985
[Presentation] 放射線によるToll様受容体の細胞表面発現制御機構の探索2016
- Author(s)
  吉野浩教
- Organizer
  日本放射線影響学会第59回大会
- Place of Presentation
  ＪＭＳアステールプラザ（広島県広島市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K15443
[Presentation] 放射線によるToll様受容体の細胞表面発現制御機構の探索2016
- Author(s)
  吉野浩教
- Organizer
  日本放射線影響学会　第59回大会
- Place of Presentation
  JMSアステールプラザ（広島県広島市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-15K09985
[Presentation] 放射線によるToll様受容体の細胞表面発現制御機構の探索.2016
- Author(s)
  吉野浩教
- Organizer
  日本放射線影響学会第59回大会
- Place of Presentation
  ＪＭＳアステールプラザ（広島県広島市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-16H02667
[Presentation] Synergistic effects of RIG-like receptor stimulus and ionizing radiation on anticancer effects2015
- Author(s)
  Yoshino H, Kashiwakura I
- Organizer
  15th International Congress of Radiation Research ICRR 2015
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09985
[Presentation] Thrombopoietin-Mimetic Romiplostim Confers the Complete Survival Rate to Mice Exposed to Lethal Ionizing Radiation.2015
- Author(s)
  M. Yamaguchi, T. Hirouchi, M. Chiba, S. Monzen, H. Yoshino, J. Ishikawa, T. Tsujiguchi, A. Nishiyama, S. Murakami, J. Komura, I. Kashiwakura.
- Organizer
  57th American Society of Hematology (ASH2015)
- Place of Presentation
  Orlande, USA.
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15443
[Presentation] RIG-I様受容体アゴニストと放射線の併用による抗腫瘍効果増強2015
- Author(s)
  吉野浩教，柏倉幾郎
- Organizer
  日本放射線影響学会　放射線ワークショップ
- Place of Presentation
  富山大学（富山県富山市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K09985
[Presentation] Effects of a c-mpl agonist on mice exposed to lethal ionizing radiation.2015
- Author(s)
  M. Yamaguchi, T. Hirouchi, M. Chiba, S. Monzen, H. Yoshino, J. Ishikawa, T. Tsujiguchi, A. Nishiyama, S. Murakami, J. Komura, I. Kashiwakura.
- Organizer
  2st Educational Symposium on Radiation and Health by young scientists (ESRAH2015)
- Place of Presentation
  弘前大学保健学研究科（青森県弘前市）
- Year and Date
  2015-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293256
[Presentation] Thrombopoietin-Mimetic Romiplostim Confers the Complete Survival Rate to Mice Exposed to Lethal Ionizing Radiation.2015
- Author(s)
  M. Yamaguchi, T. Hirouchi, M. Chiba, S. Monzen, H. Yoshino, J. Ishikawa, T. Tsujiguchi, A. Nishiyama, S. Murakami, J. Komura, I. Kashiwakura.
- Organizer
  57th American Society of Hematology (ASH2015)
- Place of Presentation
  Orlande, USA.
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293256
[Presentation] RIG-I様受容体アゴニストと放射線の併用による抗腫瘍効果増強．2015
- Author(s)
  吉野　浩教,　柏倉　幾郎.
- Organizer
  日本放射線影響学会第1回放射線ワークショップ-未来に繋ぐ放射線研究-
- Place of Presentation
  富山大学五福キャンパス黒田講堂（富山県富山市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K15443
[Presentation] Effects of a c-mpl agonist on mice exposed to lethal ionizing radiation.2015
- Author(s)
  M. Yamaguchi, T. Hirouchi, M. Chiba, S. Monzen, H. Yoshino, J. Ishikawa, T. Tsujiguchi, A. Nishiyama, S. Murakami, J. Komura, I. Kashiwakura.
- Organizer
  15th International Congress of Radiation Research (ICRR)
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293256
[Presentation] 小胞体ストレスの放射線抵抗性マクロファージに対するアポトーシス誘導効果2015
- Author(s)
  吉野浩教，柏倉幾郎
- Organizer
  BMB2015　第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K09985
[Presentation] 致死線量放射線ばく露マウスに対するc-mpl作動薬の作用.2015
- Author(s)
  山口　平, 廣内　篤久, 千葉　満, 門前　暁, 吉野　浩教, 小村　潤一郎, 柏倉　幾郎.
- Organizer
  日本放射線影響学会第1回放射線ワークショップ-未来に繋ぐ放射線研究-
- Place of Presentation
  富山大学五福キャンパス黒田講堂（富山県富山市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K15443
[Presentation] Effect of 4-methylumbelliferone and Irradiation Combination on Factors Related to A Variety of Invasion and Metastasis.2015
- Author(s)
  Ryo Saga, Satoru Monzen, Hironori Yoshino, Mitsuru Chiba, Toshiya Nakamura, and Yoichiro Hosokawa
- Organizer
  ICRR2015, 15th International Congress of Radiation Research
- Place of Presentation
  京都国際会館（京都府　京都市）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591831
[Presentation] Effects of a c-mpl agonist on mice exposed to lethal ionizing radiation.2015
- Author(s)
  M. Yamaguchi, T. Hirouchi, M. Chiba, S. Monzen, H. Yoshino, J. Ishikawa, T. Tsujiguchi, A. Nishiyama, S. Murakami, J. Komura, I. Kashiwakura.
- Organizer
  15th International Congress of Radiation Research (ICRR)
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15443
[Presentation] Effects of a c-mpl agonist on mice exposed to lethal ionizing radiation.2015
- Author(s)
  M. Yamaguchi, T. Hirouchi, M. Chiba, S. Monzen, H. Yoshino, J. Ishikawa, T. Tsujiguchi, A. Nishiyama, S. Murakami, J. Komura, I. Kashiwakura.
- Organizer
  2st Educational Symposium on Radiation and Health by young scientists (ESRAH2015)
- Place of Presentation
  弘前大学保健学研究科（青森県弘前市）
- Year and Date
  2015-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15443
[Presentation] Effect of 4-methylumbelliferone and irradiation combination on factors related to a variety of invasion and metastasis.2015
- Author(s)
  R. Saga, S. Monzen, H. Yoshino, M. Chiba, T. Nakamura and Y. Hosokawa
- Organizer
  ESRAH2015, 2nd Educational Symposium on Radiation and Health by Young Scientists
- Place of Presentation
  弘前大学（青森　弘前市）
- Year and Date
  2015-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24591831
[Presentation] 致死線量放射線ばく露マウスに対するc-mpl作動薬の作用.2015
- Author(s)
  山口　平, 廣内　篤久, 千葉　満, 門前　暁, 吉野　浩教, 小村　潤一郎, 柏倉　幾郎.
- Organizer
  日本放射線影響学会第1回放射線ワークショップ-未来に繋ぐ放射線研究-
- Place of Presentation
  富山大学五福キャンパス黒田講堂（富山県富山市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293256
[Presentation] RIG-I様受容体アゴニストと放射線の併用による抗腫瘍効果増強．2015
- Author(s)
  吉野　浩教,　柏倉　幾郎.
- Organizer
  日本放射線影響学会第1回放射線ワークショップ-未来に繋ぐ放射線研究-
- Place of Presentation
  富山大学五福キャンパス黒田講堂（富山県富山市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25293256
[Presentation] ウイルス核酸認識受容体に及ぼす放射線の影響2013
- Author(s)
  古川真帆、吉野浩教、小堺雅貴、柏倉幾郎
- Organizer
  日本放射線影響学会　第56回大会
- Place of Presentation
  ホテルクラウンパレス青森（青森県青森市）
- Data Source
  KAKENHI-PROJECT-25861053
[Presentation] 致死線量放射線ばく露マウスに対する C-Mpl作動薬の作用2013
- Author(s)
  石川純也,廣内篤久,伊藤巧一,千葉満,中野学,門前暁,吉野浩教,羽澤勝治,中野光,山口平,田中公夫,柏倉幾郎
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森市
- Year and Date
  2013-10-18
- Data Source
  KAKENHI-PROJECT-24659553
[Presentation] ヒト単球系細胞の分化に伴う放射線抵抗性獲得機序の解明2013
- Author(s)
  小倉巧也、吉野浩教、今埜遼香、柏倉幾郎
- Organizer
  日本放射線影響学会　第56回大会
- Place of Presentation
  ホテルクラウンパレス青森（青森県青森市）
- Data Source
  KAKENHI-PROJECT-25861053
[Presentation] Beneficial Effects Of Ionizing Radiation To Enhance Anti-Cancer Effects Of RIG-Like Receptor Stimulus2013
- Author(s)
  Yoshino H, Kashiwakura I.
- Organizer
  55th ASH annual meeting and exposition
- Place of Presentation
  Ernest N. Morial Convention Center（New Orleans, USA）
- Data Source
  KAKENHI-PROJECT-25861053
[Presentation] 4-methylumbelliferone’s addition against human fibrosarucoma cells and the effect of radiation concomitant use2013
- Author(s)
  Ryo Saga, Yoichiro Hosokawa, Hironori Yoshino, Shingo Terashima, Toshiya Nakamura
- Organizer
  The 5ｔｈ International Symposium on Radiation Emergency Medicine at Hirosaki University
- Place of Presentation
  青森県青森市
- Data Source
  KAKENHI-PROJECT-24591831
[Presentation] 液晶性化合物の抗腫瘍効果と構造活性相関2013
- Author(s)
  吉野浩教、福士紗織、吉澤篤、柏倉幾郎
- Organizer
  第51回日本放射線腫瘍学会生物部会学術大会
- Place of Presentation
  東北大学（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-25861053
[Presentation] Response of the Nrf2 protection system in human monocytic cells after ionizing irradiation2012
- Author(s)
  Yoshino H, Kiminarita T, Matsushita Y,Kashiwakura I
- Organizer
  International Symposium on the Natural Radiation Exposures and Low Dose Radiation Epidemiological Studies
- Place of Presentation
  HirosakiJapan.
- Data Source
  KAKENHI-PROJECT-23791383
[Presentation] Response of the Nrf2 protection system in human monocytic cells after ionizing irradiation2012
- Author(s)
  H. Yoshino, T. Kiminarita, Y. Matsushita and I. Kashiwakura
- Organizer
  International Symposium on Natural Radiation Exposure and Low Dose Radiation Epidemiological Studies
- Place of Presentation
  Hirosaki, Japan
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] 病原体認識受容体に及ぼす放射線の影響2012
- Author(s)
  吉野浩教,柏倉幾郎
- Organizer
  第50回日本放射線腫瘍学会生物部会学術大会
- Place of Presentation
  沖縄県宜野湾市
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-23791383
[Presentation] Toll様受容体に及ぼす放射線の影響2012
- Author(s)
  吉野浩教,柏倉幾郎
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23791383
[Presentation] Toll様受容体に及ぼす放射線の影響2012
- Author(s)
  吉野　浩教，他
- Organizer
  日本放射線影響学会　第55回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23791383
[Presentation] Response of the nrf2 protection system in human monocytic cells after ionizing irradiation2012
- Author(s)
  H.Yoshino, et al.
- Organizer
  International Symposium on the Natural Radiation Exposures and Low Dose Radiation Epidemiological Studies
- Place of Presentation
  弘前市
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] 液晶関連化合物の抗腫瘍作用及び放射線増感作用の可能性2012
- Author(s)
  若佐谷拓也,吉野浩教,吉澤篤,柏倉幾郎
- Organizer
  第50回日本放射線腫瘍学会生物部会学術大会
- Place of Presentation
  沖縄県宜野湾市
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-23791383
[Presentation] 病原体認識受容体に及ぼす放射線の影響2012
- Author(s)
  吉野　浩教，他
- Organizer
  第50回日本放射線腫瘍学会生物部会学術大会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-23791383
[Presentation] 放射線照射細胞におけるNrf2生体防御システムの関与2011
- Author(s)
  吉野浩教、柏倉幾郎
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸市商工会議所会館
- Data Source
  KAKENHI-PROJECT-23791383
[Presentation] 放射線照射細胞におけるNrf2生体防御システムの関与2011
- Author(s)
  吉野浩教, 他
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] 放射線照射細胞におけるNrf2生体防御システムの関与(PB-6)2011
- Author(s)
  吉野浩教,柏倉幾郎
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] Theeffects of ionizing radiation on pattern recognition receptors2011
- Author(s)
  Yoshino H, Kashiwakura I
- Organizer
  14th International Congress of RadiationResearch
- Place of Presentation
  Warsaw, Poland.
- Data Source
  KAKENHI-PROJECT-23791383
[Presentation] 高線量放射線ばく露個体の治療に関する基礎的検討(PF-4)2011
- Author(s)
  石川純也,吉野浩教,門前暁,柏倉幾郎
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] The effects of ionizing radiation on pattern recognition receptors2011
- Author(s)
  吉野浩教、柏倉幾郎
- Organizer
  14th International Congress of Radiation Research
- Place of Presentation
  ワルシャワ、ポーランド
- Data Source
  KAKENHI-PROJECT-23791383
[Presentation] The effects of ionizing radiation on pattern recognition receptors2011
- Author(s)
  H.Yoshino, et al.
- Organizer
  14th International Congress of Radiation Research
- Place of Presentation
  ワルシャワ(ポーランド)
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] ヒト骨髄系造血の分化・増殖に与える電離放射線の影響(PB-17)2011
- Author(s)
  門前暁,吉野浩教,笠井(江口)清美,柏倉幾郎
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] 放射線照射細胞におけるNrf2生体防御システムの関与2011
- Author(s)
  吉野浩教,柏倉幾郎
- Organizer
  日本放射線影響学会第54回大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-23791383
[Presentation] The effects of ionizing radiation on pattern recognition receptors2011
- Author(s)
  H. Yoshino and I. Kashiwakura
- Organizer
  14th International Congress of Radiation Research
- Place of Presentation
  Warsaw, Poland
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] Stimulation type-dependent dendritic cells maturation from human monocytes after X-irradiation.2010
- Author(s)
  H.Yoshino, et al
- Organizer
  56th Amual Meeting Radiation Research Society
- Place of Presentation
  マウイ(ハワイ)
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] Stimulation type-dependent dendritic cells maturation from human monocytes after X-irradiation2010
- Author(s)
  H. Yoshino, K. Takahashi and I. Kashiwakura
- Organizer
  56th Annual Meeting Radiation Research Society
- Place of Presentation
  Grand Wailea Resort Hotel and Spa, Maui, Hawaii
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] ヒト末梢血単球由来樹状細胞の分化誘導における放射線の影響2009
- Author(s)
  吉野浩教、高橋賢次、柏倉幾郎
- Organizer
  第48回日本医学放射線学会生物部会学術大会
- Place of Presentation
  富山
- Year and Date
  2009-07-10
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] 重粒子線照射ヒト造血幹・前駆細胞からの初期造血における発現遺伝子の変化2009
- Author(s)
  門前暁、高橋賢次、吉野浩教、笠井-江口清美、柏倉幾郎
- Organizer
  第48回日本医学放射線学会生物部会学術大会
- Place of Presentation
  富山
- Year and Date
  2009-07-10
- Data Source
  KAKENHI-PROJECT-21390336
[Presentation] ヒト肺がん細胞のウイルス核酸認識受容体の応答性に及ぼす放射線の影響．
- Author(s)
  吉野浩教，柏倉幾郎．
- Organizer
  第43回制癌シンポジウム・第52回生物部会学術大会
- Place of Presentation
  メルパルク京都（京都府京都市）
- Year and Date
  2014-07-11 – 2014-07-12
- Data Source
  KAKENHI-PROJECT-25861053
[Presentation] Effects of ionizing radiation on differentiation and induction of murine bone marrow-derived mast cells
- Author(s)
  S. Murakami, H. Yoshino, J. Ishikawa, M. Yamaguchi, T. Tsujiguchi, A. Nishiyama, K. Yokoyama, I. Kashiwakura
- Organizer
  The 1st Educational Symposium on RADIATION AND HEALTH by Young Scientists
- Place of Presentation
  ホテルニューキャッスル（青森県弘前市）
- Year and Date
  2014-09-21 – 2014-09-22
- Data Source
  KAKENHI-PROJECT-25293256
[Presentation] Inhibition of malignant tumor metastasis by 4-methylumbelliferone on X-irradiation.
- Author(s)
  Ryo Saga, Satoru Monzen, Hironori Yoshino, Mitsuru Chiba, Toshiya Nakamura, Yoichiro Hosokawa
- Organizer
  19th World Congress on Advances in Oncology
- Place of Presentation
  ギリシャ　アテネ
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24591831
[Presentation] 致死線量放射線ばく露マウスに対するC-Mpl作動薬の作用
- Author(s)
  石川純也，廣内篤久，伊藤巧一，千葉満，中野学，門前暁，吉野浩教，羽澤勝治，中野光，山口平，田中公夫，柏倉幾郎
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  クラウンパレス青森（青森市）
- Data Source
  KAKENHI-PROJECT-24659553
[Presentation] 致死線量放射線ばく露マウスに対するC-Mpl作動薬の作用
- Author(s)
  石川純也，廣内篤久，伊藤巧一，千葉満，中野学，門前暁，吉野浩教，羽澤勝治，中野光，山口平，田中公夫，柏倉幾郎
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森市
- Data Source
  KAKENHI-PROJECT-25293256
[Presentation] マウス骨髄細胞由来肥満細胞の分化・増殖に対する放射線の影響
- Author(s)
  村上翔，吉野浩教，山口平，西山彩香，横山昂生，柏倉幾郎
- Organizer
  第43回制癌シンポジウム・第52回生物部会学術大会
- Place of Presentation
  メルパルク京都（京都府京都市）
- Year and Date
  2014-07-11 – 2014-07-12
- Data Source
  KAKENHI-PROJECT-25293256
[Presentation] Synergistic effects of RIG-like receptor stimulus and ionizing radiation on anticancer effects
- Author(s)
  Yoshino H, Kashiwakura I.
- Organizer
  the 15th International Congress of Radiation Research (ICRR2015)
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2015-05-25 – 2015-05-29
- Data Source
  KAKENHI-PROJECT-25861053
[Presentation] 国内承認医薬品を組合せた急性放射線障害治療プロトコールの探索
- Author(s)
  柏倉幾郎，伊藤巧一，中野　学，千葉　満，門前　暁，吉野浩教
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  東北大学川内北キャンパス（仙台市）
- Data Source
  KAKENHI-PROJECT-24659553
[Presentation] Effects of ionizing radiation on retinoic acid-inducible gene-I-like receptors
- Author(s)
  H. Yoshino, T. Saitoh, M. Kozakai, I. Kashiwakura
- Organizer
  The 9th International Symposium on the Natural Radiation Environment
- Place of Presentation
  ホテルニューキャッスル（青森県弘前市）
- Year and Date
  2014-09-22 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-25293256
[Presentation] ヒト肺がん細胞のウイルス核酸認識受容体の応答性に及ぼす放射線の影響
- Author(s)
  吉野浩教，柏倉幾郎
- Organizer
  第43回制癌シンポジウム・第52回生物部会学術大会
- Place of Presentation
  メルパルク京都（京都府京都市）
- Year and Date
  2014-07-11 – 2014-07-12
- Data Source
  KAKENHI-PROJECT-25293256
[Presentation] Effects of a c-mpl Receptor Agonist on Mice Exposed to Lethal Ionizing Radiation
- Author(s)
  M. Yamaguchi, T. Hirouchi, M. Chiba, S. Monzen, H. Yoshino, J. Ishikawa, T. Tsujiguchi, A, Nishiyama, S, Murakami, J. Komura, I. Kashiwakura
- Organizer
  The 9th International Symposium on the Natural Radiation Environment
- Place of Presentation
  ホテルニューキャッスル（青森県弘前市）
- Year and Date
  2014-09-22 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-25293256
[Presentation] マウス骨髄細胞由来肥満細胞の分化・増殖に対する放射線の影響．
- Author(s)
  村上翔，吉野浩教，山口平，西山彩香，横山昂生，柏倉幾郎．
- Organizer
  第43回制癌シンポジウム・第52回生物部会学術大会
- Place of Presentation
  メルパルク京都（京都府京都市）
- Year and Date
  2014-07-11 – 2014-07-12
- Data Source
  KAKENHI-PROJECT-25861053
[Presentation] Effects of ionizing radiation on retinoic acid-inducible gene-I-like receptors.
- Author(s)
  Yoshino H, Saitoh T, Kozakai M, Kashiwakura I.
- Organizer
  The 9th International Symposium on the Natural Radiation Environment (NRE-IX)
- Place of Presentation
  ホテルニューキャッスル（青森県弘前市）
- Year and Date
  2014-09-22 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-25861053

1. MONNOZEN Satoru (20514136)

# of Collaborated Projects: 9 results

# of Collaborated Products: 29 results
2. KASHIWAKURA Ikuo (00177370)

# of Collaborated Projects: 7 results

# of Collaborated Products: 68 results
3. CHIBA Mitsuru (20583735)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. TERASHIMA Shingo (00583733)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. TAKAHASHI Kenji (00400143)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. HOSOKAWA Yoichiro (70173599)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. HAZAWA Masakatsu (40622460)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. ITO Koichi (90398579)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
9. 三浦富智 (20261456)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. ABE Yoshinao (10167950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KONDO Takashi (40143937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NAKAMURA Toshiya (00155847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. NOTO YUKA (80250629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 漆坂真弓 (70326304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 北島麻衣子 (70455731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 稲波修 (10193559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 渡邉純 (10201188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 中井雄治 (10321788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 細田正洋 (30457832)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 床次眞司 (80247254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 山村仁 (10438228)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 山盛徹 (00512675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 岩岡和輝 (70466051)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 紺野宏記 (80419267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 吉沢篤

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 桑原義和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. WONG W・R

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoshino Hironori 吉野 浩教

YOSHINO Hironori 吉野 浩教

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パターン認識受容体cGASが介在する放射線応答制御の解明と癌放射線治療への応用Principal Investigator

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The mechanisms by which RIG-I-like receptor pathways modulate cellular radiation responsePrincipal Investigator

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Effects of DAMPs from cancer cells exposed to radiation on the properties of cancer cellsPrincipal Investigator

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Enhancement of radiation therapy for cancer treatment by focusing on pattern recognition receptorsPrincipal Investigator

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Effects of ionizing radiation on the pattern recognition receptors.Principal Investigator

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Yoshino Hironori 吉野浩教

YOSHINO Hironori 吉野浩教