Hata Nobuhiro 秦暢宏

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HATA Nobuhiro 秦暢宏

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Researcher Number	10596034
Other IDs	https://orcid.org/0000-0002-5523-7166
Affiliation (Current)	2024: 大分大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 大分大学, 医学部, 准教授 2022: 九州大学, 大学病院, 助教 2017 – 2021: 九州大学, 大学病院, 講師 2016: 独立行政法人国立病院機構九州医療センター(臨床研究センター), その他部局等, 医師 2013: 独立行政法人国立病院機構九州医療センター(臨床研究センター), その他部局等, その他 2013: 独立行政法人国立病院機構九州医療センター, 臨床研究センター 2011 – 2013: 九州大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Cerebral neurosurgery Except Principal Investigator Basic Section 56010:Neurosurgery-related / Cerebral neurosurgery / Basic Section 59010:Rehabilitation science-related / Neurosurgery
Keywords	Principal Investigator glioma / molecular diagnosis / digital PCR / WHO2021 / liquid biopsy / TERT / IDH / H3F3A / glioblastoma / 神経膠腫 … More / 分子診断 / リキッドバイオプシー / cfDNA / CSF / MLPA / H3 / ゲノム / 脳・神経 / トランスレーショナルリサーチ / 癌 / 遺伝子 / point mutation / H3 G34R / H3 K27M / BRAF / HRM / diffuse glioma / WHO2016 / genetic analysis / 1p/19q LOH / chromosome 10 / genome sequencer / micro RNA / cancer stem cell / IDH2 / IDH1 / LOH / next-generation sequencing / 脳腫瘍 … More Except Principal Investigator バイオマーカー / 脳腫瘍 / エクソソーム / グリオーマ / microRNA / 一次運動野 / 左背外側前頭前野 / 特許 / 経頭蓋磁気刺激 / コロナ後遺症 / 下垂体腺腫 / 免疫ゲノム / 直接誘導ミクログリア様細胞 / 免疫微小環境 / ミクログリア / 免疫免疫環境 / リキッドバイオプシー / 頭蓋内胚細胞腫瘍 / 胚細胞腫瘍 / 分子病理学 / exosome / glioma / DNA損傷応答 / 膠芽腫 / micro RNA / マクロファージ / 脳動脈瘤 / 間葉系幹細胞 / エキソソーム / 神経膠腫 Less

Comprehensive molecular diagnosis of glioma by liquid biopsyPrincipal Investigator
- Principal Investigator
  
  秦暢宏
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Oita University
Strategy to Attack Coronavirus Infections Brain Fog-Central Nervous System Sequelae Using a Novel Patented Technology
- Principal Investigator
  
  藤木稔
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Oita University
Elucidation of glioma immune microenvironment heterogeneity based on immunogenomics by liquid biopsy
- Principal Investigator
  
  溝口昌弘
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyushu University
下垂体腺腫における血中cfDNAのエピジェネティクス解析と臨床応用
- Principal Investigator
  
  空閑太亮
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyushu University
Development of non-invasive diagnostic system of glioma by liquid biopsy liquid biopsyPrincipal Investigator
- Principal Investigator
  
  Hata Nobuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Oita University
  Kyushu University
Development of an innovative diagnostic / therapeutic system for intracranial germ cell tumors
- Principal Investigator
  
  KUGA DAISUKE
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyushu University
Development of comprehensive platform for molecular diagnosis of gliomaPrincipal Investigator
- Principal Investigator
  
  Hata Nobuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyushu University
  National Hospital Organization, Kyushu Medical Center (Clinical Institute)
Investigation of brain tumor derived exosomes; the role in tumorigeneity and therapy
- Principal Investigator
  
  Mizoguchi Masahiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyushu University
Potential novel treatment approach for cerebral aneurysm with mesenchymal stem cell
- Principal Investigator
  
  NAKAMIZO AKIRA
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyushu University
The dynamics of DNA damage response in glioblastoma-Toward the development of new therapy-
- Principal Investigator
  
  YOSHIMOTO KOJI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyushu University
Identification of a novel biomarker of brain tumor based on the analysis of exosomal microRNA
- Principal Investigator
  
  MIZOGUCHI Masahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyushu University
Comprehensive analysis of glioma LOH regions using next-generation sequencingPrincipal Investigator
- Principal Investigator
  
  HATA Nobuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kyushu University

All 2022 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Changes in the Relapse Pattern and Prognosis of Glioblastoma After Approval of First-Line Bevacizumab: A Single-Center Retrospective Study2022
- Author(s)
  Funakoshi Y, Takigawa K, Hata N, Kuga D, Hatae R, Sangatsuda Y, Fujioka Y, Otsuji R, Sako A, Yoshitake T, Togao O, Hiwatashi A, Iwaki T, Mizoguchi M, Yoshimoto K.
- Journal Title
  
  World Neurosurg
  
  Volume: 159 Pages: e479-e487
- DOI
  10.1016/j.wneu.2021.12.075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03044
[Journal Article] Liquid biopsy with multiplex ligation-dependent probe amplification targeting cell-free tumor DNA in cerebrospinal fluid from patients with adult diffuse glioma2022
- Author(s)
  Ryosuke Otsuji
- Journal Title
  
  Neuro oncology advance
  
  Volume: 5 Issue: 1 Pages: 1-11
- DOI
  10.1093/noajnl/vdac178
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16690, KAKENHI-PROJECT-21H03044, KAKENHI-PROJECT-20K09392
[Journal Article] A case of ganglioglioma grade 3 with H3 K27M mutation arising in the medial temporal lobe in an elderly patient2022
- Author(s)
  Fujii Yutaro、Hatae Ryusuke、Hata Nobuhiro、Suzuki Satoshi O.、Sangatsuda Yuhei、Takigawa Kosuke、Funakoshi Yusuke、Fujioka Yutaka、Kuga Daisuke、Mizoguchi Masahiro、Iwaki Toru、Yoshimoto Koji
- Journal Title
  
  Neuropathology
  
  Volume: 42 Issue: 3 Pages: 197-203
- DOI
  10.1111/neup.12793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09392
[Journal Article] Clinical implications of molecular analysis in diffuse glioma stratification2021
- Author(s)
  Mizoguchi Masahiro、Hata Nobuhiro、Kuga Daisuke、Hatae Ryusuke、Akagi Yojiro、Sangatsuda Yuhei、Fujioka Yutaka、Takigawa Kosuke、Funakoshi Yusuke、Suzuki Satoshi O.、Iwaki Toru
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 38 Issue: 3 Pages: 210-217
- DOI
  10.1007/s10014-021-00409-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03044, KAKENHI-PROJECT-20K09392
[Journal Article] Current trend in treatment of glioblastoma in Japan: a national survey using the diagnostic procedure combination database (J-ASPECT study-glioblastoma)2021
- Author(s)
  Funakoshi Yusuke、Hata Nobuhiro、Kuga Daisuke、Hatae Ryusuke、Sangatsuda Yuhei、Fujioka Yutaka、Takigawa Kosuke、Yoshimoto Koji、Mizoguchi Masahiro、Iihara Koji
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 26 Issue: 8 Pages: 1441-1449
- DOI
  10.1007/s10147-021-01929-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09392
[Journal Article] Volumetric study reveals the relationship between outcome and early radiographic response during bevacizumab-containing chemoradiotherapy for unresectable glioblastoma2021
- Author(s)
  Takigawa Kosuke、Hata Nobuhiro、Michiwaki Yuhei、Hiwatashi Akio、Yonezawa Hajime、Kuga Daisuke、Hatae Ryusuke、Sangatsuda Yuhei、Fujioka Yutaka、Funakoshi Yusuke、Otsuji Ryosuke、Sako Aki、Togao Osamu、Yoshiura Takashi、Yoshimoto Koji、Mizoguchi Masahiro
- Journal Title
  
  Journal of Neuro-Oncology
  
  Volume: 154 Issue: 2 Pages: 187-196
- DOI
  10.1007/s11060-021-03812-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03044, KAKENHI-PROJECT-20K09392
[Journal Article] Molecular diagnosis of diffuse glioma using a chip-based digital PCR system to analyze IDH, TERT, and H3 mutations in the cerebrospinal fluid2021
- Author(s)
  Fujioka Yutaka、Hata Nobuhiro、Akagi Yojiro、Kuga Daisuke、Hatae Ryusuke、Sangatsuda Yuhei、Michiwaki Yuhei、Amemiya Takeo、Takigawa Kosuke、Funakoshi Yusuke、Sako Aki、Iwaki Toru、Iihara Koji、Mizoguchi Masahiro
- Journal Title
  
  Journal of Neuro-Oncology
  
  Volume: 152 Issue: 1 Pages: 47-54
- DOI
  10.1007/s11060-020-03682-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09392
[Journal Article] CD206 Expression in Induced Microglia-Like Cells From Peripheral Blood as a Surrogate Biomarker for the Specific Immune Microenvironment of Neurosurgical Diseases Including Glioma2021
- Author(s)
  Tanaka Shunya、Ohgidani Masahiro、Hata Nobuhiro、Inamine Shogo、Sagata Noriaki、Shirouzu Noritoshi、Mukae Nobutaka、Suzuki Satoshi O.、Hamasaki Hideomi、Hatae Ryusuke、Sangatsuda Yuhei、Fujioka Yutaka、Takigawa Kosuke、Funakoshi Yusuke、Iwaki Toru、Hosoi Masako、Iihara Koji、Mizoguchi Masahiro、Kato Takahiro A.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 670131-670131
- DOI
  10.3389/fimmu.2021.670131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04042, KAKENHI-PROJECT-21H03044, KAKENHI-PROJECT-20K09392, KAKENHI-PROJECT-19H03752
[Journal Article] Clinical significance of CDKN2A homozygous deletion in combination with methylated <i>MGMT</i> status for <i>IDH</i> ‐wildtype glioblastoma2021
- Author(s)
  Funakoshi Yusuke、Hata Nobuhiro、Takigawa Kosuke、Arita Hideyuki、Kuga Daisuke、Hatae Ryusuke、Sangatsuda Yuhei、Fujioka Yutaka、Sako Aki、Umehara Toru、Yoshitake Tadamasa、Togao Osamu、Hiwatashi Akio、Yoshimoto Koji、Iwaki Toru、Mizoguchi Masahiro
- Journal Title
  
  Cancer Medicine
  
  Volume: 10 Issue: 10 Pages: 3177-3187
- DOI
  10.1002/cam4.3860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09392
[Journal Article] Relevance of calcification and contrast enhancement pattern for molecular diagnosis and survival prediction of gliomas based on the 2016 World Health Organization Classification2019
- Author(s)
  Michiwaki Yuhei、Hata Nobuhiro、Mizoguchi Masahiro、Hiwatashi Akio、Kuga Daisuke、Hatae Ryusuke、Akagi Yojiro、Amemiya Takeo、Fujioka Yutaka、Togao Osamu、Suzuki Satoshi O.、Yoshimoto Koji、Iwaki Toru、Iihara Koji
- Journal Title
  
  Clinical Neurology and Neurosurgery
  
  Volume: 187 Pages: 105556-105556
- DOI
  10.1016/j.clineuro.2019.105556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08970
[Journal Article] Pediatric ganglioglioma with an H3 K27M mutation arising from the cervical spinal cord2018
- Author(s)
  Okuda Tomohiro、Hata Nobuhiro、Suzuki Satoshi O、Yoshimoto Koji、Arimura Koichi、Amemiya Takeo、Akagi Yojiro、Kuga Daisuke、Oba Utako、Koga Yuhki、Ohga Shouichi、Iwaki Toru、Iihara Koji
- Journal Title
  
  Neuropathology
  
  Volume: in press Issue: 4 Pages: 422-427
- DOI
  10.1111/neup.12471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10779
[Journal Article] The effectiveness of salvage treatments for recurrent lesions of oligodendrogliomas previously treated with upfront chemotherapy2018
- Author(s)
  Kuga Daisuke、Hata Nobuhiro、Akagi Yojiro、Amemiya Takeo、Sangatsuda Yuhei、Hatae Ryusuke、Yoshimoto Koji、Mizoguchi Masahiro、Iihara Koji
- Journal Title
  
  World Neurosurgery
  
  Volume: in press Pages: e735-e742
- DOI
  10.1016/j.wneu.2018.03.069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-18K08970
[Journal Article] Reclassification of 400 consecutive glioma cases based on the revised 2016WHO classification.2018
- Author(s)
  Akagi Y, Yoshimoto K, Hata N, Kuga D, Hatae R, Amemiya T, Sangatsuda Y, Suzuki SO, Iwaki T, Mizoguchi M, Iihara K.
- Journal Title
  
  Brain tumor pathology
  
  Volume: 35 Issue: 2 Pages: 81-89
- DOI
  10.1007/s10014-018-0313-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20015, KAKENHI-PROJECT-18K08970, KAKENHI-PROJECT-16K10779
[Journal Article] An elderly case of malignant small cell glioma with hemorrhage coexistent with a calcified pilocytic astrocytoma component in the cerebellar hemisphere2018
- Author(s)
  Sangatsuda Yuhei、Hata Nobuhiro、Suzuki Satoshi O.、Akagi Yojiro、Hatae Ryusuke、Kuga Daisuke、Yoshimoto Koji、Momosaki Seiya、Iwaki Toru、Iihara Koji
- Journal Title
  
  Neuropathology
  
  Volume: 38 Issue: 5 Pages: 493-497
- DOI
  10.1111/neup.12478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10779
[Journal Article] High-resolution melting and immunohistochemical analysis efficiently detects mutually exclusive genetic alterations of adamantinomatous and papillary craniopharyngiomas2017
- Author(s)
  Yoshimoto Koji、Hatae Ryusuke、Suzuki Satoshi O.、Hata Nobuhiro、Kuga Daisuke、Akagi Yojiro、Amemiya Takeo、Sangatsuda Yuhei、Mukae Nobutaka、Mizoguchi Masahiro、Iwaki Toru、Iihara Koji
- Journal Title
  
  Neuropathology
  
  Volume: 38 Issue: 1 Pages: 3-10
- DOI
  10.1111/neup.12408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] Prevalence and clinicopathological features of H3.3 G34-mutant high-grade gliomas: a retrospective study of 411 consecutive glioma cases in a single institution.2017
- Author(s)
  Yoshimoto K, Hatae R, Sangatsuda Y, Suzuki SO, Hata N, Akagi Y, Kuga D, Hideki M, Yamashita K, Togao O, Hiwatashi A, Iwaki T, Mizoguchi M, Iihara K.
- Journal Title
  
  Brain Tumor Pathol.
  
  Volume: 印刷中 Issue: 3 Pages: 103-112
- DOI
  10.1007/s10014-017-0287-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15529, KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] A comprehensive analysis identifies BRAF hotspot mutations associated with gliomas with peculiar epithelial morphology.2016
- Author(s)
  Hatae R, Hata N, Suzuki SO, Yoshimoto K, Kuga D, Murata H, Akagi Y, Sangatsuda Y, Iwaki T, Mizoguchi M, Iihara K.
- Journal Title
  
  Neuropathology
  
  Volume: 28 Issue: 3 Pages: 191-199
- DOI
  10.1111/neup.12347
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15529, KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] Add-on bevacizumab can prevent early clinical deterioration and prolong survival in newly diagnosed partially resected glioblastoma patients with a poor performance status.2016
- Author(s)
  Hata N, Yoshimoto K, Hatae R, Kuga D, Akagi Y, Sangatsuda Y, Suzuki SO, Shono T, Mizoguchi M, Iihara K.
- Journal Title
  
  Onco Targets Ther.
  
  Volume: 10 Pages: 429-437
- DOI
  10.2147/ott.s125587
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15529, KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] Insular primary glioblastomas with IDH mutations: Clinical and biological specificities.2016
- Author(s)
  Hata N, Hatae R, Yoshimoto K, Murata H, Kuga D, Akagi Y, Sangatsuda Y, Suzuki SO, Iwaki T, Mizoguchi M, Iihara K.
- Journal Title
  
  Neuropathology
  
  Volume: 24 Issue: 3 Pages: 200-207
- DOI
  10.1111/neup.12362
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15529, KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] Precise Detection of IDH1/2 and BRAF Hotspot Mutations in Clinical Glioma Tissues by a Differential Calculus Analysis of High-Resolution Melting Data.2016
- Author(s)
  Hatae R, Hata N, Yoshimoto K, Kuga D, Akagi Y, Murata H, Suzuki SO, Mizoguchi M, Iihara K.
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 8 Pages: e0160489-e0160489
- DOI
  10.1371/journal.pone.0160489
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K10779
[Journal Article] Deferred radiotherapy and upfront procarbazine-ACNU-vincristine administration for 1p19q codeleted oligodendroglial tumors are associated with favorable outcome without compromising patient performance, regardless of WHO grade.2016
- Author(s)
  Hata N, Yoshimoto K, Hatae R, Kuga D, Akagi Y, Suzuki SO, Iwaki T, Shono T, Mizoguchi M, Iihara K.
- Journal Title
  
  Onco Targets Ther.
  
  Volume: 9 Pages: 7123-7131
- DOI
  10.2147/ott.s115911
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15529, KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] Detection of proneural/mesenchymal marker expression in glioblastoma: temporospatial dynamics and association with chromatin-modifying gene expression2015
- Author(s)
  Hideki Murata･Koji Yoshimoto･Ryusuke Hatae･Yojiro Akagi･Masahiro Mizoguchi･Nobuhiro Hata･Daisuke Kuga･Akira Nakamizo･Toshiyuki Amano･Tetsuro Sayama･Koji Iihara
- Journal Title
  
  Journal of Neuro-oncology
  
  Volume: 125 Issue: 1 Pages: 33-41
- DOI
  10.1007/s11060-015-1886-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462185, KAKENHI-PROJECT-15K15529, KAKENHI-PROJECT-25293311
[Journal Article] Clinical implications of microRNAs in human glioblastoma2013
- Author(s)
  Mizoguchi M, Guan Y, Yoshimoto K, Hata N, Amano T, Nakamizo A, Sasaki T
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 3 Pages: 19-19
- DOI
  10.3389/fonc.2013.00019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390280, KAKENHI-PROJECT-23659691
[Journal Article] Complex DNA repair pathways as possible therapeutic targets to overcome temozolomide resistance in glioblastoma2012
- Author(s)
  Yoshimoto K, Mizoguchi M, Hata N, Murata H, Hatae R, Amano T, Nakamizo A, Sasaki T
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 2 Pages: 186-186
- DOI
  10.3389/fonc.2012.00186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390280, KAKENHI-PROJECT-23659691
[Journal Article] Associations between microRNA expression and mesenchymal marker gene expression in glioblastoma.2012
- Author(s)
  Ma X, Yoshimoto K, Guan Y, Hata N, Mizoguchi M, et. al.
- Journal Title
  
  Neuro Oncol.
  
  Volume: 14 Pages: 1153-1162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791608
[Journal Article] Molecular characteristics of glioblastoma with 1p/19q co-deletion2012
- Author(s)
  Mizoguchi M, Yoshimoto K, Ma X, Guan Y, Hata N, Amano T, Nakamizo A, Suzuki SO, Iwaki T, Sasaki T
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 29(3) Issue: 3 Pages: 148-53
- DOI
  10.1007/s10014-012-0107-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390280, KAKENHI-PROJECT-23500429, KAKENHI-PROJECT-23659691
[Journal Article] Associations between microRNA expression and mesenchymal marker gene expression in glioblastoma2012
- Author(s)
  Xinlong Ma
- Journal Title
  
  Neuro-Oncology
  
  Volume: 14 Issue: 9 Pages: 1153-1162
- DOI
  10.1093/neuonc/nos145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390279, KAKENHI-PROJECT-22390280, KAKENHI-PROJECT-23659691
[Journal Article] MicroRNAs in Human Malignant Gliomas2012
- Author(s)
  Mizoguchi M, Guan Y, Yoshimoto K, Hata N, Amano T, Nakamizo A, Sasaki T
- Journal Title
  
  J Oncol
  
  Volume: 2012 Pages: 732874-732874
- DOI
  10.1155/2012/732874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390280, KAKENHI-PROJECT-23659691
[Journal Article] Molecular biomarkers of glioblastoma: current targets and clinical implications2012
- Author(s)
  Yoshimoto K, Mizoguchi M, Hata N, Amano T, Nakamizo A, Sasaki T
- Journal Title
  
  Current Biomarker Findings
  
  Volume: 2012(2) Pages: 63-76
- URL
  http://dx.doi.org/10.2147/CBF.S25590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659691
[Journal Article] Molecular characteristics of glioblastoma with 1p/19q co-deletion2012
- Author(s)
  Mizoguchi M, Yoshimoto K, Ma X, Guan Y, Hata N, et. al.
- Journal Title
  
  Brain Tumor Pathol.
  
  Volume: 29 Pages: 148-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791608
[Journal Article] Molecular biomarkers of glioblastoma: current targets and clinical implications2012
- Author(s)
  Yoshimoto K, Mizoguchi M, Hata N, et. al.
- Journal Title
  
  Current Biomarker Findings
  
  Volume: 2 Pages: 63-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791608
[Journal Article] Loss of heterozygosity analysis in malignant gliomas2011
- Author(s)
  Mizoguchi M, Kuga D, Guan Y, Hata N, Nakamizo A, Yoshimoto K, Sasaki T
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 28(3) Issue: 3 Pages: 191-6
- DOI
  10.1007/s10014-011-0038-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390280, KAKENHI-PROJECT-23659691
[Presentation] 膠芽腫に対する積極的摘出の意義：volumetric解析による検証2022
- Author(s)
  秦暢宏;尾辻亮介;三月田祐平;藤岡寛;瀧川浩介;舟越勇介;空閑太亮;中溝玲;溝口昌弘;吉本幸司
- Organizer
  第81回日本脳神経外科学会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] Diffuse gliomaに対する髄液中cell free DNAを用いたliquid biopsyの現状と課題2022
- Author(s)
  藤岡寛, 尾辻亮介, 舟越勇介, 瀧川浩介, 三月田祐平, 空閑太亮, 秦暢宏, 中溝玲, 溝口昌弘, 吉本幸司
- Organizer
  一般社団法人日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 膠芽腫に対する拡大的摘出は予後を改善するか？2022
- Author(s)
  秦暢宏;尾辻亮介;三月田祐平;藤岡寛;瀧川浩介;舟越勇介;空閑太亮;中溝玲;溝口昌弘;吉本幸司
- Organizer
  第27回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] IDH-mutant神経膠腫におけるCDKN2A/B欠失の予後への影響2022
- Author(s)
  尾辻亮介，秦暢宏，三月田祐平，藤岡寛，瀧川浩介，舟越勇介，野口直樹, 空閑　太亮，中溝　玲，溝口昌弘, 吉本幸司
- Organizer
  第39回日本脳腫瘍学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 当院におけるRosette-forming glioneuronal tumorの経験2022
- Author(s)
  藤岡寛、瀧川浩介、三月田祐平、空閑太亮、秦暢宏、溝口昌弘、吉本幸司
- Organizer
  第39回日本脳腫瘍学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] IDH-mutant神経膠腫におけるCDKN2A/B欠失の予後への影響2022
- Author(s)
  尾辻亮介，秦暢宏，三月田祐平，藤岡寛，瀧川浩介，舟越勇介，野口直樹, 空閑　太亮，中溝　玲，溝口昌弘, 吉本幸司
- Organizer
  一般社団法人日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] ヒト血液由来誘導ミクログリア様細胞の貪食能についての検討2022
- Author(s)
  前原直喜, 白水寛理, 田中俊也, 扇谷昌宏, 三月田祐平, 藤岡寛, 空閑太亮, 秦暢宏, 溝口昌弘, 加藤隆弘, 吉本幸司
- Organizer
  一般社団法人日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 当院のMicrosatellite instabilityを有するGBMにおける遺伝的および免疫学的プロファイルの検討2021
- Author(s)
  瀧川浩介, 波多江龍亮, 三木健嗣, 尾辻亮介, 舟越勇介, 藤岡寛, 三月田祐平, 空閑太亮秦暢宏, 溝口昌弘, 吉本幸司
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 膠芽腫におけるsupra-maximal resection の予後への影響2021
- Author(s)
  尾辻亮介,秦暢宏,舟越勇介,溝口昌弘,空閑太亮,三月田祐平, 藤岡寛, 瀧川浩介, 吉本幸司
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] グリオーマ分子診断に応じた手術治療戦略2021
- Author(s)
  秦暢宏
- Organizer
  第41回日本脳神経外科コングレス
- Invited
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] 膠芽腫におけるsupra-maximal resection の予後への影響2021
- Author(s)
  尾辻亮介,秦暢宏,舟越勇介,溝口昌弘,空閑太亮,三月田祐平, 藤岡寛, 瀧川浩介, 吉本幸司
- Organizer
  第39回日本脳腫瘍学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 1p19q co-del oligodendrogliomaに対するPAVの有効性：分子診断による治療層別化の長期成績2021
- Author(s)
  秦暢宏、溝口昌弘、空閑太亮、三月田祐平、藤岡寛、瀧川浩介、舟越勇介、尾辻亮介、吉本幸司
- Organizer
  第80回日本脳神経外科学会総会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] Gliomaの免疫微小環境バイオマーカーとしてのヒト血液由来ミクログリア様(iMG)細胞の有用性の検討2021
- Author(s)
  田中俊也、扇谷昌宏、秦暢宏、稲嶺翔吾、佐方功明、迎伸孝、波多江龍亮、三月田祐平、岩城徹、細井昌子、溝口昌弘、加藤隆弘
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] Current Trend in Treatment of Glioblastoma in Japan: A National Survey Using the Diagnostic Procedure Combination Database (J-ASPECT Study-Glioblastoma)2021
- Author(s)
  Nobuhiro Hata1), Yusuke Funakoshi1), Daisuke Kuga1), Yuhei Sangatsuda1), Yutaka Fujioka1), Kosuke Takigawa1), Koji Yoshimoto1), Masahiro Mizoguchi1), Koji Iihara2)
- Organizer
  The 39th Annual Meeting of the Japan Society for Neuro-Oncology
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] 初発脳腫瘍における髄液中cell free DNA量の検討2021
- Author(s)
  藤岡寛, 尾辻亮介, 舟越勇介, 瀧川浩介, 三月田祐平, 空閑太亮, 秦暢宏, 溝口昌弘吉本幸司
- Organizer
  第39回日本脳腫瘍学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] Diffuse midline gliomaに対するcell free DNAを用いたliquid biopsy2021
- Author(s)
  藤岡寛、尾辻亮介、舟越勇介、瀧川浩介、三月田祐平、空閑太亮秦　暢宏、溝口昌弘、吉本幸司
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 脳腫瘍に対するがんゲノム医療の現状と展望2021
- Author(s)
  溝口昌弘、秦暢宏、空閑太亮、三月田裕平、藤岡寛、瀧川浩介、舟越勇介
- Organizer
  第29回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 膠芽腫はどこまで摘出すべきか？volumetric解析による検証2021
- Author(s)
  秦暢宏、溝口昌弘，尾辻亮介，舟越勇介，空閑太亮，三月田祐平，藤岡寛，瀧川浩介，吉本幸司
- Organizer
  第26回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] がんゲノム医療時代のグリオーマ治療戦略2021
- Author(s)
  溝口昌弘、秦暢宏、空閑太亮、三月田裕平、藤岡寛、瀧川浩介、舟越勇介、吉本幸司
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 髄液中cell free tumor DNAを用いたDiffuse gliomaの分子診断2020
- Author(s)
  藤岡寛、秦　暢宏、空閑太亮、赤木洋二郎、波多江龍亮、三月田祐平、瀧川浩介、舟越勇介、溝口昌弘.
- Organizer
  日本脳神経外科学会第78回学術総会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] 髄液中cell free DNA解析によるdiffuse gliomaの分子診断2020
- Author(s)
  藤岡寛, 秦暢宏, 空閑太亮, 波多江龍亮, 三月田祐平, 瀧川浩介, 舟越勇介, 溝口昌弘
- Organizer
  第37回日本脳腫瘍学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] The correlation between 1p19q and TERT promoter mutation status in IDH-mutant gliomas2018
- Author(s)
  Nobuhiro Hata, Masahiro MIizoguchi, Yojiro Akagi, Satoshi O Suzuki, Daisuke Kuga, Takeo Amemiya, Ryusuke Hatae, Koji Yoshimoto, Toru Iwaki, Koji Iihara
- Organizer
  The 19th International Congress of Neuropathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] 高解像度融解曲線の２階微分解析による、グリオーマ点変異の高精度判定：HRM-MI法2017
- Author(s)
  秦暢宏、波多江龍亮、吉本幸司、空閑大亮、雨宮健生、赤木洋二郎、三月田祐平、溝口昌弘、飯原弘二
- Organizer
  日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] 1p19q co-deletionを有する oligodendrogliomaに対するPAV先行治療：分子診断による治療層別化の長期成績2017
- Author(s)
  秦暢宏、吉本幸司、空閑太亮、波多江龍亮、赤木洋二郎、鈴木諭、岩城徹、溝口昌弘、飯原弘二
- Organizer
  第34回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] 改良HRM解析法による、高精度なグリオーマ分子診断法の開発2017
- Author(s)
  秦暢宏、波多江龍亮、吉本幸司、空閑大亮、赤木洋二郎、三月田祐平、鈴木諭、岩城徹、溝口昌弘、飯原弘二
- Organizer
  日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] 初発膠芽腫に対するBevacizumab承認後の新規治療戦略：現況と展望2016
- Author(s)
  秦暢宏、吉本幸司、溝口昌弘、波多江龍亮、赤木洋二郎、三月田祐平、空閑太亮、庄野禎久、飯原弘二
- Organizer
  第75回日本脳神経外科学会総会
- Place of Presentation
  福岡県　福岡市
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] Deferred Radiotherapy and Upfront Procarbazine-ACNU-Vincristine Administration for 1p19q Codeleted Oligodendroglial Tumors is Associated with Favorable Outcome without Compromising Patient Performance, Regardless of WHO Grade2016
- Author(s)
  Nobuhiro HATA, Koji YOSHIMOTO, Daisuke KUGA, Ryusuke HATAE, Yojiro AKAGI, Satoshi O SUZUKI, Toru IWAKI, Masahiro MIZOGUCHI, Koji IIHARA
- Organizer
  The 14th Young-Honam and Kyushu Neurosurgical Joint Meeting
- Place of Presentation
  福岡県　福岡市
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] 初発神経膠芽腫に対するBevacizumab併用療法の治療成績2016
- Author(s)
  秦暢宏、吉本幸司、空閑太亮、波多江龍亮、赤木洋二郎、三月田祐平、溝口昌弘、、飯原弘二
- Organizer
  第34回日本脳腫瘍学会
- Place of Presentation
  山梨県　甲府市
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] 神経膠芽腫症例におけるBRAF遺伝子点突然変異解析2015
- Author(s)
  波多江龍亮、秦暢宏、鈴木諭、赤木洋二郎、村田秀樹、天野敏之、吉本幸司、溝口昌弘、飯原弘二
- Organizer
  第33回日本脳腫瘍病理学会
- Place of Presentation
  香川県高松市
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-25293311
[Presentation] IDH/TERT変異解析による、グリオーマの分子病理学的層別化：255症例の検討2015
- Author(s)
  波多江龍亮、秦暢宏、赤木洋二郎、村田秀樹、空閑太亮、吉本幸司、溝口昌弘、飯原弘二
- Organizer
  日本脳神経外科学会第74回学術総会
- Place of Presentation
  北海道札幌市
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-25293311
[Presentation] pGBMにおけるIDH/TERT promoter/ch10 LOHの解析2015
- Author(s)
  波多江龍亮、秦暢宏、赤木洋二郎、村田秀樹、空閑太亮、吉本幸司、溝口昌弘、飯原弘二
- Organizer
  第33回日本脳腫瘍学会学術集会
- Place of Presentation
  京都府京都市
- Year and Date
  2015-12-06
- Data Source
  KAKENHI-PROJECT-25293311
[Presentation] High grade glioma 診断における遺伝子解析の役割2013
- Author(s)
  溝口昌弘、吉本幸司、秦暢宏、村田秀樹、波多江龍亮、天野敏之、中溝玲、鈴木論、岩城徹、佐々木富男
- Organizer
  第31回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293311
[Presentation] 神経膠腫におけるmicroRNA発現解析の意義2013
- Author(s)
  溝口昌弘、吉本幸司、村田秀樹、波多江龍亮、秦暢宏、天野敏之、中溝玲
- Organizer
  日本脳神経外科学会第72回学術総会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-25293311
[Presentation] Long-term outcome of patients with oligodendroglial tumors treated up-front with PAV therapy2013
- Author(s)
  秦　暢宏
- Organizer
  Joint Neurosurgical Convention 2013
- Place of Presentation
  Hawaii Wailkoloa Village (Hawaii)
- Data Source
  KAKENHI-PROJECT-23791608
[Presentation] ダイレクトシークエンス法によるIDH1 mutation解析：グリオーマ126例での検討2011
- Author(s)
  秦　暢宏
- Organizer
  第29回日本脳腫瘍病理学会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-23791608
[Presentation] grade II, IIIグリオーマの遺伝子解析と治療成績：IDH1 mutationは予後因子か？2011
- Author(s)
  秦　暢宏
- Organizer
  第70回日本脳神経外科学会総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-23791608
[Presentation] IDH mutant primary GBMの臨床像2011
- Author(s)
  秦　暢宏
- Organizer
  第29回日本脳腫瘍学会
- Place of Presentation
  下呂温泉水明館(岐阜）
- Data Source
  KAKENHI-PROJECT-23791608
[Presentation] HRM法によるIDH1 mutation解析
- Author(s)
  秦　暢宏
- Organizer
  第30回日本脳腫瘍病理学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-23791608
[Presentation] Secondary glioblastoma症例における免疫染色法によるIDH1遺伝子変異同定について～シークエンス法との比較～
- Author(s)
  波多江龍亮、秦暢宏、赤木洋二郎、村田秀樹、天野敏之、中溝玲、鈴木諭、吉本幸司、溝口昌弘、飯原弘二
- Organizer
  第32回脳腫瘍病理学会
- Place of Presentation
  徳島
- Year and Date
  2014-05-23 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25293311
[Presentation] IDH1 /2変異解析簡便化の試み
- Author(s)
  秦　暢宏
- Organizer
  第30回日本脳腫瘍学会学術集会
- Place of Presentation
  グランドプリンスホテル広島（広島）
- Data Source
  KAKENHI-PROJECT-23791608
[Presentation] 高解像度融解曲線法(HRM)によるBRAF V600E 及びH3F3A変異解析の試み
- Author(s)
  波多江龍亮、秦暢宏、赤木洋二郎、村田秀樹、天野敏之、吉本幸司、溝口昌弘、飯原弘二
- Organizer
  第73回脳神経外科学会学術総会
- Place of Presentation
  東京
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25293311
[Presentation] テモダール時代において、PAV療法はOligodendroglial tumorに対する有用な選択肢となり得るか？
- Author(s)
  秦　暢宏
- Organizer
  日本脳神経外科学会第71回学術総会
- Place of Presentation
  大阪国際会議場（大阪）
- Data Source
  KAKENHI-PROJECT-23791608
[Presentation] 高齢者に対するテモダール放射線同期療法の治療成績
- Author(s)
  秦　暢宏
- Organizer
  第26回日本老年脳神経外科学会
- Place of Presentation
  東京ステーションコンファレンス（東京）
- Data Source
  KAKENHI-PROJECT-23791608
[Presentation] GliomaにおけるBRAF点突然変異の解析
- Author(s)
  波多江龍亮、秦暢宏、赤木洋二郎、村田秀樹、天野敏之、吉本幸司、溝口昌弘、飯原弘二
- Organizer
  第32回日本脳腫瘍学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2014-11-30 – 2014-12-02
- Data Source
  KAKENHI-PROJECT-25293311

1. MIZOGUCHI Masahiro (50380621)

# of Collaborated Projects: 6 results

# of Collaborated Products: 47 results
2. KUGA DAISUKE (40759932)

# of Collaborated Projects: 6 results

# of Collaborated Products: 40 results
3. NAKAMIZO Akira (80529800)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
4. YOSHIMOTO Koji (70444784)

# of Collaborated Projects: 4 results

# of Collaborated Products: 32 results
5. AMANO Toshiyuki (70448413)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
6. 三月田祐平 (00848640)

# of Collaborated Projects: 4 results

# of Collaborated Products: 27 results
7. 藤岡寛 (10914252)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
8. KIKKAWA Yuichiro (80423515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 赤木洋二郎 (10570773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 波多江龍亮 (20570774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 樋渡昭雄 (30444855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 栂尾理 (10452749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 加藤隆弘 (70546465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. 扇谷昌宏 (60636455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 札場博貴 (00772930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 籾井泰朋 (20534192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 藤木稔 (90231563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MURATA Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 飯原弘二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hata Nobuhiro 秦 暢宏

HATA Nobuhiro 秦 暢宏

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Comprehensive molecular diagnosis of glioma by liquid biopsyPrincipal Investigator

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Development of non-invasive diagnostic system of glioma by liquid biopsy liquid biopsyPrincipal Investigator

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Development of comprehensive platform for molecular diagnosis of gliomaPrincipal Investigator

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Comprehensive analysis of glioma LOH regions using next-generation sequencingPrincipal Investigator

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[Journal Article] Changes in the Relapse Pattern and Prognosis of Glioblastoma After Approval of First-Line Bevacizumab: A Single-Center Retrospective Study2022

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[Journal Article] Liquid biopsy with multiplex ligation-dependent probe amplification targeting cell-free tumor DNA in cerebrospinal fluid from patients with adult diffuse glioma2022

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[Journal Article] A case of ganglioglioma grade 3 with H3 K27M mutation arising in the medial temporal lobe in an elderly patient2022

Hata Nobuhiro 秦暢宏

HATA Nobuhiro 秦暢宏