Yanagita Ryo 柳田亮

… Alternative Names

YANAGITA Ryo 柳田亮

Less

Researcher Number	10598121
Other IDs
Affiliation (Current)	2022: 香川大学, 農学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2022: 香川大学, 農学部, 准教授 2011 – 2015: 香川大学, 農学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 38040:Bioorganic chemistry-related / Bioproduction chemistry/Bioorganic chemistry / Bioorganic chemistry Except Principal Investigator Science and Engineering / Bioproduction chemistry/Bioorganic chemistry
Keywords	Principal Investigator がん / プロテインキナーゼC / 炎症 / 発がんプロモーション / 白血病 / 希少糖 / D-allose / allose / C1ドメイン / タプシガルギン … More / セスキテルペンラクトン / アナログ設計 / 構造活性相関 / 分子動力学シミュレーション / CH-O水素結合 / 天然物 / 骨格多様性 … More Except Principal Investigator プロテインキナーゼＣ / ホルボールエステル / プロテインキナーゼC / アプリシアトキシン / ブリオスタチン / がん細胞増殖抑制 / 発がんプロモーター / シグナル伝達 / 発がん促進物質 / アルツハイマー病 / アプログ / 抗がん剤 / debromoaplysiatoxin / bryostatin / phorbol ester / 発がん促進 / ヒトがん細胞 / 増殖抑制 / がん細胞 / aplysiatoxin / 細胞増殖抑制活性 / 発がん2段階試験 / TPA / 海洋天然物 / がん / 海綿 / 珪藻 / フサコケムシ / ラン藻 / Epstein-Barrウィルス / 機械学習 / アロタケタール / HIV / 癌 / 有機化学 / 薬理学 / 酵素 / CH/π相互作用 / マクラマイシン / ヒト免疫不全ウイルス Less

Structural optimization of vibsanins with scaffold diversity as protein kinase C activatorPrincipal Investigator
- Principal Investigator
  
  柳田亮
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Kagawa University
Structure–activity study and analysis of mechanism of action of vibsanins focused on pro-/anti-inflammatory switchingPrincipal Investigator
- Principal Investigator
  
  Yanagita Ryo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Kagawa University
Unified comprehension of chemical communication by natural PKC ligands and development of new medicinal seeds
- Principal Investigator
  
  Irie Kazuhiro
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Development of C1 domain ligand with selectivity for non-PKC type C1 domain-containing proteinsPrincipal Investigator
- Principal Investigator
  
  Yanagita Ryo C.
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Kagawa University
Development and mechanistic analysis of new PKC ligands as anti-cancer agents
- Principal Investigator
  
  IRIE Kazuhiro
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Search for novel PKC ligands as therapeutic seeds for intractable diseases
- Principal Investigator
  
  IRIE Kazuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Kyoto University
Development and mechanism of action of rare sugar derivatives with antiproliferative effectPrincipal Investigator
- Principal Investigator
  
  YANAGITA Ryo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Kagawa University

All 2022 2021 2020 2019 2018 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Patent

[Journal Article] Design, synthesis, and biological activity of a synthetically accessible analog of aplysiatoxin with an (R)-(－)-carvone-based conformation-controlling unit2022
- Author(s)
  Suzuki Yoshiyuki、Moritoki Keiichi、Kajiwara Mizuki、Yanagita Ryo C.、Kawanami Yasuhiro、Hanaki Yusuke、Irie Kazuhiro
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 86
- DOI
  10.1093/bbb/zbac084
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06405
[Journal Article] AI and computational chemistry-accelerated development of an alotaketal analogue with conventional PKC selectivity2022
- Author(s)
  Maki Jumpei、Oshimura Asami、Tsukano Chihiro、Yanagita Ryo C、Saito Yutaka、Sakakibara Yasubumi、Irie Kazuhiro
- Journal Title
  
  Chemical Communications
  
  Volume: 58
- DOI
  10.1039/d2cc01759h
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06405
[Journal Article] Analysis of binding mode of vibsanin A with protein kinase C C1 domains: An experimental and molecular dynamics simulation study2022
- Author(s)
  Ryo C. Yanagita, Mao Otani, Satoshi Hatanaka, Hiroto Nishi, Shota Miyake, Yusuke Hanaki, Masashi Sato, Yasuhiro Kawanami, Kazuhiro Irie
- Journal Title
  
  Journal of Molecular Structure
  
  Volume: 1260 Pages: 132866-132866
- DOI
  10.1016/j.molstruc.2022.132866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05846, KAKENHI-PLANNED-17H06405
[Journal Article] Effects of side chain length of 10-methyl-aplog-1, a simplified analog of debromoaplysiatoxin, on PKC binding, anti-proliferative, and pro-inflammatory activities2021
- Author(s)
  Atsuko Gonda, Koji Takada, Ryo C. Yanagita, Shingo Dan, and Kazuhiro Irie*
- Journal Title
  
  Bioscience, Biotechnology and Biochemistry
  
  Volume: 85 Issue: 1 Pages: 168-180
- DOI
  10.1093/bbb/zbaa024
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06405, KAKENHI-PROJECT-16H06276
[Journal Article] Synthesis and biological activities of simplified aplysiatoxin analogs focused on the CH/pi interaction.2020
- Author(s)
  Takumi Kobayashi, Ryo, C. Yanagita, Kazuhiro Irie
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Pages: 127657-127657
- DOI
  10.1016/j.bmcl.2020.127657
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06405, KAKENHI-PROJECT-16H06276
[Journal Article] Synthesis, conformation, and biological activities of a des-A-ring analog of 18-deoxy-aplog-l, a simplified analog of debromoaplysiatoxin2019
- Author(s)
  Ashida, Y., Yanagita, R. C., Kawanami, Y., Okamura, M., Dan, S. and Irie, K.
- Journal Title
  
  Heterocycles
  
  Volume: 99
- DOI
  10.3987/com-18-s(f)60
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06405, KAKENHI-PROJECT-16H06276
[Journal Article] Synthesis and biological activities of acetal analogs at position 3 of 10-methyl-aplog-1, a potential anti-cancer lead derived from debromoaplysiatoxin.2018
- Author(s)
  Hayakawa K, Hanaki Y, Tokuda H, Yanagita RC, Nakagawa Y, Okamura M, Dan S, Irie K.
- Journal Title
  
  Heterocycles.
  
  Volume: 97 Issue: 1 Pages: 478-492
- DOI
  10.3987/com-18-s(t)37
- Description
  in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06405, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H05105
[Journal Article] Structural optimization of 10-methyl-aplog-1, a simplified 1 analog of 2 debromoaplysiatoxin, as an anticancer lead.2016
- Author(s)
  M. Kikumori, R. C. Yanagita, H. Tokuda, K. Suenaga, H. Nagai, and *K. Irie
- Journal Title
  
  Biosci. Biotech. Biochem.
  
  Volume: 80 Pages: 221-231
- DOI
  10.1080/09168451.2015.1091718
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23102011, KAKENHI-PROJECT-16K01911
[Journal Article] Binding mode prediction of aplysiatoxin, a potent agonist of protein kinase C, through moleculer simulation and structure-activity study on simplified analogs of the receptor-recognition domain2016
- Author(s)
  Y Ashida, R. C. Yanagita*, C Takahashi, Y Kawanami, K Irie
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 24 Pages: 4218-4227
- DOI
  10.1016/j.bmc.2016.07.011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102011
[Journal Article] Synthesis and biological activities of the amide derivative of aplog-1, a simplified analog of aplysiatoxin with anti-proliferative and cytotoxic activities2015
- Author(s)
  Yusuke Hanaki, Ryo C. Yanagita, Takahiro Sugahara, Misako Aida, Harukuni Tokuda, Nobutaka Suzuki, Kazuhiro Irie
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 印刷中 Pages: 888-895
- DOI
  10.1080/09168451.2014.1002452
- NAID
  120005676639
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23102011, KAKENHI-PUBLICLY-26102733
[Journal Article] Improved and large-scale synthesis of 10-methyl-aplog-1, a potential lead for an anticancer drug2014
- Author(s)
  Masayuki Kikumori, Ryo C. Yanagita, and Kazuhiro Irie
- Journal Title
  
  Tetrahedron
  
  Volume: 70 Pages: 9776-9782
- DOI
  10.1016/j.tet.2014.11.026
- NAID
  120005522771
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J02518, KAKENHI-PLANNED-23102011
[Journal Article] Anti-proliferative activity of 6-O-acyl-D-allose against the human leukemia MOLT-4F cell line2014
- Author(s)
  R. C. Yanagita, K. Kobashi, C. Ogawa, Y. Ashida, H. Yamaashi, Y. Kawanami
- Journal Title
  
  Biosci. Biotechnol. Biochem
  
  Volume: 78 Pages: 190-194
- DOI
  10.1080/09168451.2014.882747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23780117
[Journal Article] Synthesis and biological activities of simplified analogs of the natural PKC ligands, bryostatin-1 and aplysiatoxin2014
- Author(s)
  Kazuhiro Irie, Ryo C. Yanagita
- Journal Title
  
  Chem. Rec.
  
  Volume: 14 Pages: 251-267
- DOI
  10.1002/tcr.201300036
- NAID
  120005651918
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23102011
[Journal Article] Effects of the methoxy group in the side chain of debromoaplysiatoxin on its tumor-promoting and anti-proliferative activities2013
- Author(s)
  Ryo C. Yanagita, Hiroaki Kamachi, Masayuki Kikumori, Harukuni Tokuda, Nobutaka Suzuki, Kiyotake Suenaga, Hiroshi Nagai and Kazuhiro Irie
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23 Pages: 4319-4323
- DOI
  10.1016/j.bmcl.2013.05.096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J02518, KAKENHI-PLANNED-23102011
[Journal Article] Structure-activity studies on the side chain of a simplified analog of aplysiatoxin (aplog-1) with anti-proliferative activity2013
- Author(s)
  Kamachi, H., Tanaka, K., Yanagita, R. C., Murakami, A., Murakami, K., Tokuda, H., Suzuki, N., Nakagawa, Y., Irie, K.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 21 Pages: 2695-2702
- DOI
  10.1016/j.bmc.2013.03.013
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102011
[Journal Article] Identification and Biological Activities of Bryostatins from Japanese Bryozoan2012
- Author(s)
  Sayo Ueno
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 76 Issue: 5 Pages: 1041-1043
- DOI
  10.1271/bbb.120026
- NAID
  10030753324
- ISSN
  0916-8451, 1347-6947
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23658100
[Patent] 新規アプリシアトキシン誘導体及びそれを含有する抗がん剤2013
- Inventor(s)
  入江一浩, 菊森将之, 蒲池弘明, 柳田亮, 中川優
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-04-16
- Acquisition Date
  2017-07-07
- Data Source
  KAKENHI-PLANNED-23102011
[Patent] 新規アプリシアトキシン誘導体及びそれを含有する抗がん剤2012
- Inventor(s)
  入江一浩，菊森将之，蒲池弘明，柳田　亮，中川　優
- Industrial Property Rights Holder
  入江一浩，菊森将之，蒲池弘明，柳田　亮，中川　優
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-092842
- Filing Date
  2012-04-16
- Data Source
  KAKENHI-PLANNED-23102011
[Presentation] B環を除去したAplysiatoxin単純化アナログの合成と生物活性2022
- Author(s)
  関戸智紀、山本剛史、柳田亮、花木祐輔、川浪康弘、入江一浩
- Organizer
  2022年度日本農芸化学会大会（京都）オンライン開催
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] (-)-Carvoneを用いるAplysiatoxin単純化アナログの合成と活性評価2022
- Author(s)
  鈴木芳幸、守時恵一、梶原瑞生、柳田亮、川浪康弘、花木祐輔、入江一浩
- Organizer
  2022年度日本農芸化学会大会（京都）オンライン開催
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] アロタケタール類のトランスデカリン型単純化アナログの合成とPKC結合活性2022
- Author(s)
  眞木準平、押村亜沙美、塚野千尋、柳田亮、入江一浩
- Organizer
  2022年度日本農芸化学会大会（京都）オンライン開催
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] アロタケタール類のシスピラン環型単純化アナログの合成とPKC結合活性2022
- Author(s)
  奥田創元、塚野千尋、柳田亮、入江一浩
- Organizer
  2022年度日本農芸化学会大会（京都）オンライン開催
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] CH/π相互作用に着目したAplysiatoxin単純化アナログの分子動力学解析2021
- Author(s)
  柳田亮、小林巧美、権田敦子、高田晃児、入江一浩
- Organizer
  日本農芸化学会2021年度大会（オンライン開催）
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] Development of new protein kinase C ligands using a machine learning model2021
- Author(s)
  Irie Kazuhiro、Tsukano Chihiro、Maki Jumpei、Oshimura Asami、Okuda Sogen、Gonda Atsuko、Yanagita Ryo C.、Saito Yutaka、Sakakibara Yasubumi
- Organizer
  2021 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2021) virtual
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] Synthesis and biological activities of des-A-ring analog of 18-deoxy-aplog-1, a simplified analog of debromoaplysiatoxin2021
- Author(s)
  Yanagita Ryo C.、Ashida Yoshiki、Kawanami Yasuhiro、Okamoto Mutsumi、Dan Shingo、Irie Kazuhiro
- Organizer
  2021 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2021) virtual
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] B環を除去したAplysiatoxin単純化アナログの合成研究2021
- Author(s)
  山本剛資、柳田　亮、川浪康弘、入江一浩
- Organizer
  日本農芸化学会中四国支部第58回講演会（オンライン開催）
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] スピロ環をもたないaplysiatoxin単純化アナログの合成とPKCアイソザイム結合活性2019
- Author(s)
  押村亜沙美、早川皓太郎、花木祐輔、柳田亮、入江一浩
- Organizer
  2019年度日本農芸化学会大会（東京農大、東京）
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] Synthesis, conformation, and biological activities of a des-A-ring analog of 18-deoxy-aplog-1, a simplified analog of debromoaplysiatoxin2019
- Author(s)
  Ashida Yoshiki、Yanagita Ryo C.、Kawanami Yasuhiro、Okamura Mutsumi、Dan Shingo、Irie Kazuhiro
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」第1回国際シンポジウム（一橋大学一橋講堂、東京）
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] サンゴジュの花芽に含まれるビブサニン類の分析と生物活性評価2019
- Author(s)
  柳田亮、植松紗和子、西皓冬、川浪康弘、入江一浩
- Organizer
  2019年度日本農芸化学会大会（東京農大、東京）
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] スピロ環を簡略化したアプリシアトキシン単純化アナログの合成，配座，および生物活性2019
- Author(s)
  柳田亮、芦田能基、川浪康弘、旦慎吾、岡村睦美、入江一浩
- Organizer
  2018年度先端モデル動物支援プラットフォーム成果発表会（琵琶湖ホテル、大津市）
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] スピロ環をもたないアプリシアトキシン単純化アナログの合成、配座、および活性2018
- Author(s)
  芦田能基、柳田亮、川浪康弘、入江一浩
- Organizer
  2018年度日本農芸化学会大会（名城大学、名古屋市）
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] サンゴジュに含まれるビブサニン類のプロテインキナーゼC結合活性の評価と結合様式の予測2018
- Author(s)
  植松紗和子、柳田亮、三宅翔太、川浪康弘、入江一浩
- Organizer
  日本農芸化学会2018年度中四国支部大会（島根大学松江キャンパス、松江市）
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] アプリシアトキシン単純化アナログ・10-Me-Aplog-1の3位アセタール型アナログの合成2018
- Author(s)
  早川皓太郎、花木祐輔、徳田春邦、柳田亮、中川優、入江一浩
- Organizer
  2018年度日本農芸化学会大会（名城大学、名古屋市）
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] アプリシアトキシン単純化アナログ・10-Me-aplog-1の側鎖誘導体の合成と活性2018
- Author(s)
  高田晃児、花木祐輔、菊森将之、徳田春邦、柳田亮、入江一浩
- Organizer
  2018年度日本農芸化学会大会（名城大学、名古屋市）
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] 抗腫瘍性Aplysiatoxin単純化アナログ・10-Me-Aplog-1のアセタール型アナログの合成と生物活性2018
- Author(s)
  早川皓太郎、花木祐輔、徳田春邦、柳田亮、中川優、入江一浩
- Organizer
  第60回天然有機化合物討論会（久留米シティープラザ、福岡県久留米市）
- Data Source
  KAKENHI-PLANNED-17H06405
[Presentation] ThapsigarginのC1ドメインに対する結合能と結合選択性の評価2016
- Author(s)
  高橋知世，柳田亮，川浪康弘，入江一浩
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-15K18691
[Presentation] AplysiatoxinのPKC C1ドメイン認識部位の構造活性相関研究2015
- Author(s)
  芦田能基、柳田　亮、川浪康弘、入江一浩
- Organizer
  2015年度日本農芸化学会大会
- Place of Presentation
  岡山大学津島キャンパス（岡山市）
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PLANNED-23102011
[Presentation] Aplysiatoxin 単純化アナログのアミド誘導体の合成と活性2015
- Author(s)
  花木祐輔、柳田　亮、菅原貴弘、相田美砂子、徳田春邦、鈴木信孝、入江一浩
- Organizer
  2015年度日本農芸化学会大会
- Place of Presentation
  岡山大学津島キャンパス（岡山市）
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PLANNED-23102011
[Presentation] Synthesis of 6-O-decanoyl-1,2-didehydro-1,2-dideoxy-D-a llose and Its Biological Activity on Plant Growth2014
- Author(s)
  Md. Tazul Islam Chowdhury, Ryo C. Yanagita, Yasuhiro Kawanami
- Organizer
  日本農芸化学会中四国支部第38回講演会
- Place of Presentation
  高松
- Year and Date
  2014-01-25
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] フラノース型D-アロース中鎖脂肪酸エステルのヒト白血病MOLT-4F細胞増殖抑制活性2014
- Author(s)
  小橋克哉,柳田亮,芦田能基,山足陽和,川浪康弘
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  川崎
- Year and Date
  2014-03-29
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] アプリシアトキシン単純化アナログ（Aplog-1）の抗がん剤シーズとしての構造最適化2014
- Author(s)
  菊森将之、柳田　亮、中川　優、蒲池弘明、徳田春邦、鈴木信孝、入江一浩
- Organizer
  新学術領域研究・がん支援「化学療法基盤支援活動」第3回シンポジウム
- Place of Presentation
  万国津梁館（沖縄県、名護市）
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PLANNED-23102011
[Presentation] D-アロース中鎖脂肪酸エステルのヒト白血病細胞増殖抑制活性2013
- Author(s)
  柳田亮,小川知紗,小橋克哉,川浪康弘
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台
- Year and Date
  2013-03-26
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] Synthesis of 6-O-decanoyl-D-altrose and Its Biological Activity on Plant Growth2013
- Author(s)
  Md. Tazul Islam Chowdhury, Ryo C. Yanagita, Yasuhiro Kawanami
- Organizer
  日本農芸化学会関西・中四国・西日本支部,日本ビタミン学会近畿・中国四国・九州沖縄地区2013年度合同広島大会
- Place of Presentation
  広島
- Year and Date
  2013-09-05
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] 植物生長抑制作用を有する希少糖誘導体の親水性官能基が生物活性に与える影響2012
- Author(s)
  柳田亮，山足陽和，橋谷矩史，川浪康弘
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学（京都市）
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] Synthesis and biological activity of 6-O-D-allose derivatives2012
- Author(s)
  Ryo C. Yanagita, Norifumi Hashitani, Yasuhiro Kawanami
- Organizer
  13^<th> Tetrahedron Symposium–Asia edition
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2012-11-27
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] 日本産フサコケムシに含まれるブリオスタチン類の同定と活性評価2012
- Author(s)
  植野紗代,柳田亮,村上一馬,村上明,徳田春邦,鈴木信孝,藤原健史,入江一浩
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-23658100
[Presentation] D-グロース脂肪酸エステルの合成と植物生長抑制活性2012
- Author(s)
  内藤まどか,柳田亮,川浪康弘
- Organizer
  日本農芸化学会中四国支部第34回講演会
- Place of Presentation
  山口
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] 植物生長抑制活性を有するD-アロース誘導体の構造活性相関2012
- Author(s)
  橋谷矩史,柳田亮,川浪康弘
- Organizer
  日本農芸化学会中四国支部第34回講演会
- Place of Presentation
  山口
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] 植物生長抑制作用を有する希少糖誘導体の親水性官能基が生物活性に与える影響2012
- Author(s)
  柳田亮,山足陽和,橋谷矩史,川浪康弘
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] 植物生長抑制作用を有するD-アロース誘導体の構造活性相関研究2011
- Author(s)
  橋谷矩史,柳田亮,川浪康弘
- Organizer
  2011年日本化学会西日本大会
- Place of Presentation
  徳島
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] 植物生長抑制作用を有するD-アロース誘導体の構造活性相関研究2011
- Author(s)
  柳田亮,橋谷矩史,川浪康弘
- Organizer
  日本農芸化学会中四国支部第30回講演会
- Place of Presentation
  岡山
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] D-グロース脂肪酸エステルの合成と生物活性2011
- Author(s)
  内藤まどか,柳田亮,川浪康弘
- Organizer
  2011年日本化学会西日本大会
- Place of Presentation
  徳島
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] D-グロース脂肪酸エステルの合成と生物活性2011
- Author(s)
  内藤まどか，柳田亮，川浪康弘
- Organizer
  2011年日本化学会西日本大会
- Place of Presentation
  徳島大学（徳島市）
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] フラノース型D-アロース中鎖脂肪酸エステルのヒト白血病MOLT-4F細胞増殖抑制活性
- Author(s)
  小橋克哉，柳田亮，芦田能基，山足陽和，川浪康弘
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス (神奈川県川崎市)
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] D-アロース中鎖脂肪酸エステルのヒト白血病細胞増殖抑制活性
- Author(s)
  柳田亮，小川知紗，小橋克哉，川浪康弘
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学（仙台市）
- Data Source
  KAKENHI-PROJECT-23780117
[Presentation] 日本産フサコケムシに含まれるブリオスタチン類の同定と活性評価
- Author(s)
  植野紗代、柳田亮、村上一馬、村上明、徳田春邦、鈴木信孝、藤原健史、入江一浩
- Organizer
  2012年度日本農芸化学会大会
- Place of Presentation
  京都女子大学（京都市）
- Data Source
  KAKENHI-PROJECT-23658100

1. IRIE Kazuhiro (00168535)

# of Collaborated Projects: 3 results

# of Collaborated Products: 37 results
2. 塚野千尋 (70524255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 村上一馬 (80571281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 川浪康弘 (30169742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 花木祐輔 (70897818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 永井宏史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 小林和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 旦慎吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. 相田美砂子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 高田昌彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yanagita Ryo 柳田 亮

YANAGITA Ryo 柳田 亮

Research Projects

Research Products

Co-Researchers

Structural optimization of vibsanins with scaffold diversity as protein kinase C activatorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structure&#8211;activity study and analysis of mechanism of action of vibsanins focused on pro-/anti-inflammatory switchingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Unified comprehension of chemical communication by natural PKC ligands and development of new medicinal seeds

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of C1 domain ligand with selectivity for non-PKC type C1 domain-containing proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development and mechanistic analysis of new PKC ligands as anti-cancer agents

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for novel PKC ligands as therapeutic seeds for intractable diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development and mechanism of action of rare sugar derivatives with antiproliferative effectPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Design, synthesis, and biological activity of a synthetically accessible analog of aplysiatoxin with an (R)-(－)-carvone-based conformation-controlling unit2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] AI and computational chemistry-accelerated development of an alotaketal analogue with conventional PKC selectivity2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of binding mode of vibsanin A with protein kinase C C1 domains: An experimental and molecular dynamics simulation study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of side chain length of 10-methyl-aplog-1, a simplified analog of debromoaplysiatoxin, on PKC binding, anti-proliferative, and pro-inflammatory activities2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis and biological activities of simplified aplysiatoxin analogs focused on the CH/pi interaction.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis, conformation, and biological activities of a des-A-ring analog of 18-deoxy-aplog-l, a simplified analog of debromoaplysiatoxin2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis and biological activities of acetal analogs at position 3 of 10-methyl-aplog-1, a potential anti-cancer lead derived from debromoaplysiatoxin.2018

Author(s)

Journal Title

Yanagita Ryo 柳田亮

YANAGITA Ryo 柳田亮

Structure–activity study and analysis of mechanism of action of vibsanins focused on pro-/anti-inflammatory switchingPrincipal Investigator