Higuchi Kei 樋口慧

… Alternative Names

HIGUCHI Kei 樋口慧

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Researcher Number	10625304
Other IDs
Affiliation (Current)	2025: 東邦大学, 薬学部, 准教授 2025: 帝京大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 東京薬科大学, 薬学部, 講師 2021 – 2022: 東京薬科大学, 薬学部, 助教 2012 – 2018: 帝京大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy
Keywords	Principal Investigator オリゴペプチドトランスポーター / 機能制御 / 消化管上皮細胞 / 促進拡散 / トランスポーター / 小腸上皮細胞 / 側底膜 / 消化管 / 薬物輸送 / 血液脳関門 … More / オーファントランスポーター / 塩基性薬物 / エズリン / 抗アポトーシス / 細胞保護効果 / Slc6a13 / 酸化ストレス / ヒポタウリン … More Except Principal Investigator トランスポーター / 血液脳関門 / 中分子薬 / Mucin / 粘液層 / 血液脳関門モデル細胞 / ヒト血液脳関門モデル細胞 / ヒト脳移行性 / 創薬モダリティ / SLC46A3 / リソソーム / エンドサイトーシス / Mucinase / 吸収改善 / 薬物吸収 / ゲノム編集 / 糖鎖 / 遺伝子編集 / 膜結合型mucin / mucin型糖鎖 / 脂溶性抗がん剤 / Mucin型糖鎖 / Mucin‐薬物相互作用 / 薬物動態 / 吸収 / 核酸 / 輸送 / ヌクレオシド / 側底膜 / CD147 / 促進拡散 / 小腸上皮細胞 / 有機アニオン / オロト酸 / SLC16A5/MCT6 / 有機カチオントランスポーター / 有機カチオン-プロトン交換輸送系 / ヒトiPS細胞 / 塩基性薬物 / 基質認識性 / ヒト不死化脳毛細血管内皮細胞 / ヒトiPS細胞由来脳毛細血管内皮細胞 / プロトン-有機カチオン交換輸送系 / ヒトiPS由来脳毛細血管内皮細胞 / ヒト脳毛細血管モデル / 薬物認識性 / 有機カチオン輸送系 / 脳微小透析法 / オキシコドン / オピオイド受容体 / オピオイド鎮痛薬 / フロー培養システム / 循環培養システム / 有機カチオン性薬物 / 発現解析 / 輸送特性 / 遺伝子抑制 / RNAiライブラリー / ヒト由来不死化細胞株 / スケールアップ / 遺伝子解析 / 脳移行性 / カチオン性薬物 / ヒト細胞株 Less

Elucidation of the molecular mechanism of Mucin-medium molecule drug interaction
- Principal Investigator
  
  岸本久直
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of drug delivery technology using lysosomal transporters
- Principal Investigator
  
  井上勝央
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
医薬品の吸収改善を目指すオリゴペプチドトランスポーターEOPTsの分子制御機構解明Principal Investigator
- Principal Investigator
  
  樋口慧
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Absorption mechanism of nucleosides and their analogs in the gastrointestinal tract
- Principal Investigator
  
  Inoue Katsuhisa
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Identification of novel equilibrative oligopeptide transporters that may regulate drug absorption in the gastrointestinal tractPrincipal Investigator
- Principal Investigator
  
  Higuchi Kei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Evaluation of the molecular mechanism of membrane-bound mucins in intestinal drug absorption.
- Principal Investigator
  
  Kishimoto Hisanao
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
塩基性薬物輸送を担う血液脳関門オーファントランスポーターの機能解明Principal Investigator
- Principal Investigator
  
  樋口慧
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Teikyo University
Elucidation of the drug recognition properties and molecular entities of the organic cation-proton exchange system at the human blood-brain barrier
- Principal Investigator
  
  Deguchi Yoshiharu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Teikyo University
Transport aross the blood-brain barrier in relation to CNS actions of opioid analgesics
- Principal Investigator
  
  Okura Takashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Teikyo University
Development of a novel experimental evaluation method for predicting the drug delivery to the brain in human
- Principal Investigator
  
  DEGUCHI YOSHIHARU
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Teikyo University
Mechanism of hypotaurine transport by Slc6a13 for oxidative stress defensePrincipal Investigator
- Principal Investigator
  
  HIGUCHI Kei
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Teikyo University
Prediction of the human brain distribution for the central nervous system drugs using a novel human immortalized brain capillary endothelial cells
- Principal Investigator
  
  DEGUCHI Yoshiharu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Teikyo University

All 2024 2023 2022 2021 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Other

[Journal Article] The Use of Carboxyfluorescein Reveals the Transport Function of MCT6/SLC16A5 Associated with CD147 as a Chloride-Sensitive Organic Anion Transporter in Mammalian Cells2024
- Author(s)
  Sugiyama K, Shimano H, Takahashi M, Shimura Y, Shimura A, Furuya T, Tomabechi R, Shirasaka Y, Higuchi K, Kishimoto H, Inoue K
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 113 Issue: 4 Pages: 1113-1120
- DOI
  10.1016/j.xphs.2023.12.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06678
[Journal Article] Monocarboxylate Transporter 13 (MCT13/SLC16A13) Functions as a Novel Plasma Membrane Oligopeptide Transporter2023
- Author(s)
  Higuchi K, Kunieda M, Sugiyama K, Tomabechi R, Kishimoto H, Inoue K
- Journal Title
  
  Nutrients
  
  Volume: 15 Issue: 16 Pages: 3527-3527
- DOI
  10.3390/nu15163527
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06678, KAKENHI-PROJECT-21K06694
[Journal Article] Macrolide and Ketolide Antibiotics Inhibit the Cytotoxic Effect of Trastuzumab Emtansine in HER2-Positive Breast Cancer Cells: Implication of a Potential Drug-ADC Interaction in Cancer Chemotherapy2023
- Author(s)
  Kiyomiya K, Tomabechi R, Saito N, Watai K, Takada T, Shirasaka Y, Kishimoto H, Higuchi K, Inoue K
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 20 Issue: 12 Pages: 6130-6139
- DOI
  10.1021/acs.molpharmaceut.3c00490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06678, KAKENHI-PROJECT-20H00568
[Journal Article] SLC46A3 is a lysosomal proton-coupled steroid conjugate and bile acid transporter involved in transport of active catabolites of T-DM12022
- Author(s)
  Tomabechi Ryuto、Kishimoto Hisanao、Sato Taeka、Saito Naoki、Kiyomiya Keisuke、Takada Tappei、Higuchi Kei、Shirasaka Yoshiyuki、Inoue Katsuhisa
- Journal Title
  
  PNAS Nexus
  
  Volume: 1 Issue: 3
- DOI
  10.1093/pnasnexus/pgac063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07165, KAKENHI-PROJECT-21K06678, KAKENHI-PROJECT-20H00568
[Journal Article] Mammalian monocarboxylate transporter 7 (MCT7/Slc16a6) is a novel facilitative taurine transporter2022
- Author(s)
  Higuchi K, Sugiyama K, Tomabechi R, Kishimoto H, Inoue K
- Journal Title
  
  J Biol Chem
  
  Volume: 298 Issue: 4 Pages: 101800-101800
- DOI
  10.1016/j.jbc.2022.101800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06678
[Journal Article] Identification of 5-Carboxyfluorescein as a Probe Substrate of SLC46A3 and Its Application in a Fluorescence-Based In Vitro Assay Evaluating the Interaction with SLC46A32022
- Author(s)
  Tomabechi Ryuto、Miyasato Miki、Sato Taeka、Takada Tappei、Higuchi Kei、Kishimoto Hisanao、Shirasaka Yoshiyuki、Inoue Katsuhisa
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 20 Issue: 1 Pages: 491-499
- DOI
  10.1021/acs.molpharmaceut.2c00741
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07165, KAKENHI-PROJECT-21K06678, KAKENHI-PROJECT-20H00568
[Journal Article] The Glycosylated N-Terminal Domain of MUC1 Is Involved in Chemoresistance by Modulating Drug Permeation Across the Plasma Membrane2022
- Author(s)
  Miyazaki Kaori、Kishimoto Hisanao、Kobayashi Hanai、Suzuki Ayaka、Higuchi Kei、Shirasaka Yoshiyuki、Inoue Katsuhisa
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 103 Issue: 3 Pages: 166-175
- DOI
  10.1124/molpharm.122.000597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07165, KAKENHI-PROJECT-21K06695
[Journal Article] The Blood-Brain Barrier Transport Mechanism Controlling Analgesic Effects of Opioid Drugs in CNS2015
- Author(s)
  黄倉　崇、樋口　慧、出口芳春
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 135 Issue: 5 Pages: 697-702
- DOI
  10.1248/yakushi.14-00234-2
- NAID
  130005066918
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2015-05-01
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590213, KAKENHI-PROJECT-15K08080, KAKENHI-PROJECT-25460199
[Journal Article] Proton-Coupled Organic Cation Antiporter-Mediated Uptake of Apomorphine Enantiomers in Human Brain Capillary Endothelial Cell Line hCMEC/D32014
- Author(s)
  Okura T, Higuchi K, Kitamura A, Deguchi Y
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 37 Issue: 2 Pages: 286-291
- DOI
  10.1248/bpb.b13-00773
- NAID
  130003382121
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590213, KAKENHI-PROJECT-25460199
[Journal Article] System amino acid transporter SNAT2 shows subtype-specific affinity for betaine and hyperosmotic inducibility in placental trophoblasts.2014
- Author(s)
  Nishimura T, Yagi R, Usuda M, Oda K, Yamazaki M, Suda S, Takahashi Y, Okazaki F, Sai Y, Higuchi, K, Maruyama T, Tomi M, Nakashima E
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: VOL. 1838 Issue: 5 Pages: 1306-12
- DOI
  10.1016/j.bbamem.2014.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249076, KAKENHI-PROJECT-24390381, KAKENHI-PROJECT-24790171, KAKENHI-PROJECT-25462574, KAKENHI-PROJECT-25560063, KAKENHI-PROJECT-25670706, KAKENHI-PROJECT-25860396
[Journal Article] Estrogen receptor α induction by mitoxantrone increases Abcg2 expression in placental trophoblast cells.2013
- Author(s)
  Oda K, Nishimura T, Higuchi K, Ishido N, Ochi K, Iizasa H, Sai Y, Tomi M, Nakashima E.
- Journal Title
  
  J Pharm Sci
  
  Volume: 102 Issue: 9 Pages: 3364-3372
- DOI
  10.1002/jps.23549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590443, KAKENHI-PROJECT-23790199, KAKENHI-PROJECT-24790171, KAKENHI-PROJECT-25860396
[Journal Article] Evaluation of rat in vivo fetal-to-maternal transfer clearances of various xenobiotics by umbilical perfusion.2013
- Author(s)
  Nishimura T, Takanohashi T, Tomi M, Horikoshi M, Higuchi K, Sai Y, Nakashima E.
- Journal Title
  
  J Pharm Sci
  
  Volume: 102(9) Issue: 9 Pages: 3356-3363
- DOI
  10.1002/jps.23551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790171, KAKENHI-PROJECT-25860396
[Presentation] 乳がんに高発現する新規抗がん剤耐性トランスポーター2024
- Author(s)
  國枝美里、樋口慧、大塚唯斗、岸本久直、井上勝央
- Organizer
  日本薬学会144年会
- Data Source
  KAKENHI-PROJECT-21K06694
[Presentation] アクセサリータンパク質によるSlc16a6/MCT7機能制御2023
- Author(s)
  樋口　慧、國枝美里、岸本久直、井上勝央
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06694
[Presentation] ムチン型糖鎖合成酵素阻害剤talniflumateは脂溶性抗がん剤の細胞膜透過を増強する2023
- Author(s)
  伊勢大地、岸本久直、鈴木彩佳、宮崎歌織、樋口慧、井上勝央
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-21K06695
[Presentation] Regulation of localization and function of MCT7 by ancillary proteins CD147 and GP702023
- Author(s)
  K. Higuchi, M. Kunieda, H. Kishimoto, K. Inoue
- Organizer
  The international joint meeting of the 23rd International Conference on Cytochrome P450 (ICCP450) and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics (JSSX)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] 脂溶性抗がん剤の細胞膜透過性に対するムチン型糖鎖の影響2023
- Author(s)
  岸本久直、伊勢大地、鈴木彩佳、宮崎歌織、樋口慧、井上勝央
- Organizer
  第67回薬学会関東支部会
- Data Source
  KAKENHI-PROJECT-21K06695
[Presentation] アクセサリータンパク質によるSlc16a6/MCT7機能制御2023
- Author(s)
  樋口慧、國枝美里、岸本久直、井上勝央
- Organizer
  第67回薬学会関東支部会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] Methotrexate resistance by Slc16a6/MCT7 in cancer cells2023
- Author(s)
  Misato Kunieda, Yuito Otsuka, Kei Higuchi, Hisanao Kishimoto, Katsuhisa Inoue
- Organizer
  2023 International Joint Meeting of the 23rd International Conference on Cytochrome P450 and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06694
[Presentation] Regulation of localization and function of MCT7 by ancillary proteins CD147 and GP702023
- Author(s)
  Kei Higuchi, Misato Kunieda, Hisanao Kishimoto, Katsuhisa Inoue
- Organizer
  2023 International Joint Meeting of the 23rd International Conference on Cytochrome P450 and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06694
[Presentation] Impact of genetic polymorphisms in SLC46A3 on the transport function and efficacy of trastuzumab emtansine2023
- Author(s)
  N. Saito, R. Tomabechi, Y. Kawakita, K. Kiyomiya, H. Kishimoto, K. Higuchi, K. Inoue
- Organizer
  The international joint meeting of the 23rd International Conference on Cytochrome P450 (ICCP450) and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics (JSSX)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] Trastuzumab emtansineの有効性に影響を及ぼすSLC46A3遺伝子多型の探索2023
- Author(s)
  齊藤直希、苫米地隆人、川喜多佑香、清宮啓介、岸本久直、樋口慧、井上勝央
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] 蛍光基質を用いたSLC46A3機能評価系の構築と新規基質探索への応用2023
- Author(s)
  苫米地隆人、井上勝央、宮里美希、佐藤妙華、高田龍平、樋口慧、岸本久直、白坂善之
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] 新規薬剤開発および薬物療法を目指した生体内代謝物トランスポーターの機能解析2023
- Author(s)
  樋口慧
- Organizer
  第67回日本薬学会関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06694
[Presentation] SLC46A3遺伝子多型が輸送機能とトラスツズマブエムタンシンの殺細胞効果へ与える影響2023
- Author(s)
  齊藤直希、苫米地隆人、川喜多佑香、清宮啓介、岸本久直、樋口慧、井上勝央
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] Inhibition of mucin-type glycosyltransferase enhances membrane permeation of lipophilic anticancer drugs2023
- Author(s)
  H. Kishimoto, D. Ise, A. Suzuki, K. Miyazaki, K. Higuchi, K. Inoue
- Organizer
  The international joint meeting of the 23rd International Conference on Cytochrome P450 (ICCP450) and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics (JSSX)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06695
[Presentation] Methotrexate resistance by Slc16a6/MCT7 in cancer cells2023
- Author(s)
  M. Kunieda, Y. Otsuka, K. Higuchi, H. Kishimoto, K. Inoue
- Organizer
  The international joint meeting of the 23rd International Conference on Cytochrome P450 (ICCP450) and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics (JSSX)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] 蛍光プローブを用いたMCT6/SLC16A5の基質特異性の評価2023
- Author(s)
  杉山滉基、嶋野ひろ恵、樋口慧、岸本久直、井上勝央
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] マクロライド系抗菌薬がトラスツズマブエムタンシンの殺細胞効果に与える影響2023
- Author(s)
  清宮啓介、苫米地隆人、齊藤直希、渡井健太、高田龍平、白坂善之、岸本久直、樋口慧、井上勝央
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] モノカルボン酸トランスポーター6（MCT6）の輸送解析2023
- Author(s)
  杉山滉基、嶋野ひろ恵、樋口慧、志村優太、岸本久直、井上勝央
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] Substrate specificity of monocarboxylate transporter 6 (MCT6)2023
- Author(s)
  K. Sugiyama, H. Shimano, K. Higuchi, H. Kishimoto, K. Inoue
- Organizer
  The international joint meeting of the 23rd International Conference on Cytochrome P450 (ICCP450) and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics (JSSX)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] オーファントランスポーターSLC46A3の機能同定2022
- Author(s)
  苫米地隆人、岸本久直、佐藤妙華、齊藤直希、清宮啓介、高田龍平、樋口慧、白坂善之、井上勝央
- Organizer
  第16回トランスポーター研究会年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] リソソーム膜タンパク質SLC46A3の機能同定2022
- Author(s)
  苫米地隆人、岸本久直、佐藤妙華、齊藤直希、清宮啓介、高田龍平、樋口慧、白坂善之、井上勝央
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] Functional identification of SLC46A3 and its implication in the efficacy of trastuzumab emtansine2022
- Author(s)
  Ryuto Tomabechi, Hisanao Kishimoto, Taeka Sato, Naoki Saito, Keisuke Kiyomiya, Tappei Takada, Kei Higuchi, Yoshiyuki Shirasaka, Katsuhisa Inoue
- Organizer
  日本薬物動態学会第37年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] Na+依存性オリゴペプチドトランスポーターを介したβ-amyloid輸送の可能性2022
- Author(s)
  樋口　慧, V Ganapathy
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-21K06694
[Presentation] モノカルボン酸トランスポーター6（MCT6）の輸送解析2022
- Author(s)
  杉山滉基、嶋野ひろ恵、樋口慧、志村優太、岸本久直、井上勝央
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] 抗がん剤の細胞内移行性に与える糖鎖合成酵素阻害剤の影響2022
- Author(s)
  鈴木彩佳、岸本久直、宮崎歌織、樋口慧、井上勝央
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-21K06695
[Presentation] 脂溶性薬物の細胞膜透過性に対する糖鎖合成酵素阻害剤の効果2022
- Author(s)
  岸本久直、鈴木彩佳、宮崎歌織、樋口慧、井上勝央
- Organizer
  第66回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06695
[Presentation] Effect of talniflumate, a glycosyltransferase inhibitor, on mucus barrier function2022
- Author(s)
  H Kishimoto, A Suzuki,　K Miyazaki,K Higuchi, K Inoue
- Organizer
  第16回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06695
[Presentation] MCT6/SLC16A5の細胞内局在の解析と内因性基質の探索2022
- Author(s)
  杉山滉基、樋口慧、志村優太、岸本久直、井上勝央
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] SLC46A3の蛍光基質の新規同定及び基質/阻害剤探索への応用2022
- Author(s)
  苫米地隆人、宮里美希、佐藤妙華、高田龍平、樋口慧、岸本久直、白坂善之、井上勝央
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] オーファントランスポーター MCT7/Slc16a6の内因性基質の同定2022
- Author(s)
  國枝美里、樋口慧、岸本久直、井上勝央
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] The extracellular domain of MUC1 confers anticancer drug resistance and modulates drug permeability.2022
- Author(s)
  H Kishimoto, A Suzuki,　K Miyazaki,K Higuchi, K Inoue
- Organizer
  日本薬物動態学会第37年会
- Data Source
  KAKENHI-PROJECT-21K06695
[Presentation] リソソームトランスポーターSLC46A3を介したトラスツズマブエムタンシン－薬物相互作用に関する検討2022
- Author(s)
  苫米地隆人、岸本久直、佐藤妙華、齊藤直希、清宮啓介、高田龍平、樋口慧、白坂善之、井上勝央
- Organizer
  医療薬学フォーラム2022 第30回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] MCT6/SLC16A5 is a chloride sensitive organic anionic transporter2022
- Author(s)
  Koki Sugiyama, Hiroko Shimano, Kei Higuchi, Hisanao Kishimoto, Katsuhisa Inoue
- Organizer
  日本薬物動態学会第37年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] 気液界面を模倣する疎水性溶媒を用いた上皮系培養細胞における粘液産生と細胞形態への影響2021
- Author(s)
  鷹野遥、岸本久直、樋口慧、井上勝央
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-21K06695
[Presentation] Identification of an endogenous substrate of MCT62021
- Author(s)
  Koki Sugiyama, Kei Higuchi, Yuta Shimura, Hisanao Kishimoto, Katsuhisa Inoue
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-21K06678
[Presentation] ヒトiPS細胞由来脳毛細血管内皮細胞におけるトランスポーターの機能的発現2018
- Author(s)
  8.手賀悠真、黒澤俊樹、樋口　慧、山口朋子、川端健二、出口芳春
- Organizer
  日本薬剤学会第33 年会（静岡）
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] Investigation of SLC35F2 drug transport function in mouse brain and primate BBB models.2018
- Author(s)
  4.Tatsuki Mochizuki, Tadahaya Mizuno, Kei Higuchi, Yuma Tega, Toshiki Kurosawa, Tomoko Yamaguchi, Kenji Kawabata, Yoshiharu Deguchi, Hiroyuki Kusuhara
- Organizer
  第33JSSX第22MDO合同年会（金沢）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] 血液脳関門透過性を有するヒストン脱アセチル化酵素阻害剤の探索研究2018
- Author(s)
  2.住吉孝明，平中誠弥，手賀悠真，樋口慧，黒澤俊樹，出口芳春，本間光貴，新真由美，伊藤昭博，吉田稔，長岡康夫
- Organizer
  第36回メディシナルケミストリーシンポジウム（京都）
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] ヒト血液脳関門モデル細胞を用いたH+/有機カチオン交換輸送体の基質スクリーニング2018
- Author(s)
  1.手賀悠真，北村　敦，大町蕗子，黒澤俊樹，樋口慧，板垣文雄，出口芳春
- Organizer
  第３回トランスポーター研究会関東部会（千葉）
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] Characterization of mesoridazine transport in human cerebral microvessel endothelial cells, hCMEC/D32018
- Author(s)
  6.Yasuyuki Debori1, Tomoko Igari, Masanori Nakakariya, Nobuyuki Amano, Yuma Tega, Kei Higuchi, Takashi Okura and Yoshiharu Deguchi
- Organizer
  第33JSSX第22MDO合同年会（金沢）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] ゲノム編集ヒト血液脳関門細胞における薬物輸送機能評価2018
- Author(s)
  7.樋口　慧、手賀悠真、黒澤俊樹、濱弘太郎、横山和明、出口芳春
- Organizer
  日本薬剤学会第33 年会（静岡）
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] ゲノム編集ヒト血液脳関門細胞における薬物輸送機能評価2018
- Author(s)
  樋口　慧、手賀悠真、黒澤俊樹、濱弘太郎、横山和明、出口芳春
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-17K15521
[Presentation] Screening of proton-coupled organic cation antiporter substrates using hCMEC/D3 cells: an in vitro human blood-brain barrier model2018
- Author(s)
  5.Atsushi Kitamura, Yuma Tega, Toshiki Kurosawa, Kei Higuchi, Yoshiharu Deguchi
- Organizer
  第33JSSX第22MDO合同年会（金沢）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] CRISPR-Cas9システムを用いたヒト血液脳関門細胞の排出輸送系ノックアウト2017
- Author(s)
  樋口　慧、手賀悠真、黒澤俊樹、濱弘太郎、横山和明、出口芳春
- Organizer
  日本薬学会第137年回（仙台）
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] ヒトiPS由来脳毛細血管内皮細胞における薬物輸送能の解明2017
- Author(s)
  黒澤俊樹、手賀悠真、樋口　慧、山口朋子、川端健二、出口芳春
- Organizer
  第39回生体膜と薬物の相互作用シンポジウム（金沢）
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] Gene expression and　function of drug transporters in brain microvascular endothelial cells derived from human iPS cells2017
- Author(s)
  Toshiki Kurosawa, Yuma Tega, Kei Higuchi, Tomoko Yamaguchi, Kenji Kawabata, Yoshiharu Deguchi
- Organizer
  第32日本薬物動態学会年会（東京）
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] ヒト血液脳関門プロトン/有機カチオンアンチポーターの機能制御因子の解析2017
- Author(s)
  樋口　慧、近藤麻美、上松祐貴、黒澤俊樹、黄倉　崇、出口芳春
- Organizer
  日本薬学会第137年回
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] ヒト血液脳関門プロトン/有機カチオンアンチポーターの機能制御因子の解析2017
- Author(s)
  〇樋口　慧、近藤麻美、上松祐貴、黒澤俊樹、黄倉　崇、出口芳春
- Organizer
  日本薬学会第137年会
- Place of Presentation
  宮城県仙台市仙台国際センター
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K08080
[Presentation] CRISPR-Cas9システムを用いたヒト血液脳関門細胞の2017
- Author(s)
  樋口　慧、手賀悠真、黒澤俊樹、濱弘太郎、横山和明、出口芳春
- Organizer
  第39回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15521
[Presentation] H+/有機カチオン交換輸送体を標的としたHDAC阻害剤の脳へのデリバリー2017
- Author(s)
  手賀悠真、平中誠弥、樋口慧、出口芳春、伊藤昭博、吉田稔、長岡康夫、住吉孝明
- Organizer
  第39回生体膜と薬物の相互作用シンポジウム（金沢）
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] 血液脳関門におけるバレニクリンの輸送解析2016
- Author(s)
  樋口　慧、黒澤俊樹、黄倉　崇、楠原洋之、出口芳春
- Organizer
  第38回生体膜と薬物の相互作用シンポジウム（名古屋）
- Place of Presentation
  名古屋
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] Transport characteristics of varenicline in the blood-brain barrier2016
- Author(s)
  Kurosawa T, Higuchi K, Okura T, Kusuhara H, Deguchi Y.
- Organizer
  日本薬物動態学会第31年会
- Place of Presentation
  長野県松本市キッセイ文化ホール
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K08080
[Presentation] Transport characteristics of varenicline in the blood-brain barrier2016
- Author(s)
  Toshiki Kurosawa, Kei Higuchi, Takashi Okura, Hiroyuki Kusuhara, and Yoshiharu Deguchi
- Organizer
  第31日本薬物動態学会年会（松本）
- Place of Presentation
  松本
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K08381
[Presentation] Histamine H1-receptor signaling in human blood-brain barrier cells2015
- Author(s)
  Takashi Okura, Kei Higuchi, Manami Ueno , Hironao Ito, Asami Kondo, Yoshiharu Deguchi
- Organizer
  第30回日本薬物動態学会年会
- Place of Presentation
  東京（東京都江戸川区）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K08080
[Presentation] Blood-to-brain transport of apomorphine enantiomers by proton-coupled organic cation antiporter at the blood-brain barrier2015
- Author(s)
  Okura T, Higuchi K, Kitamura A, Deguchi Y
- Organizer
  11th International Conference on Cerebral Vascular Biology
- Place of Presentation
  Paris (France)
- Year and Date
  2015-07-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] Gene expression profiles in hCMEC/D3 cells with different transport activities of proton/organic cation antiporter2015
- Author(s)
  Kei Higuchi, Takashi Okura, Yuki Uematsu, Asami Kondo, Hironao Ito, Yoshiharu Deguchi
- Organizer
  第30回日本薬物動態学会年会
- Place of Presentation
  東京（東京都江戸川区）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K08080
[Presentation] Histamine H1-receptor signaling in human blood-brain barrier cells2015
- Author(s)
  Okura T, Higuchi K, Ueno M, Ito H, Kondo A, Deguchi Y
- Organizer
  第30回日本薬物動態学会年会
- Place of Presentation
  東京
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] Analysis of gene expression profiles related to the transport activity of the proton/organic cation antiport system in hCMEC/D3 cells2015
- Author(s)
  Higuchi K, Okura T, Uematsu Y, Kondo A, Ito H, Deguchi Y
- Organizer
  Barcelona BioMed Conference, Blood Brain Barrier
- Place of Presentation
  Barcelona (Spain)
- Year and Date
  2015-11-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] Gene expression profiles in hCMEC/D3 cells with different transport activities of proton/organic cation antiporter2015
- Author(s)
  Higuchi K, Okura T, Uematsu Y, Kondo A, Ito H, Deguchi Y
- Organizer
  第30回日本薬物動態学会年会
- Place of Presentation
  東京
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] Memantine uptake mediated by a functionally diverse proton-coupled organic cation antiporter in human brain endothelial cells2015
- Author(s)
  Higuchi K, Okura T, Deguchi Y
- Organizer
  The Asian Federation for Pharmaceutical Sciences (AFPS) Conference 2015
- Place of Presentation
  Bangkok (Thailand)
- Year and Date
  2015-11-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] Involvement of functionally diverse proton-coupled organic cation antiporter in blood-brain barrier transport of memantine2015
- Author(s)
  Kei Higuchi, Atsushi Kitamura, Takashi Okura, Yoshiharu Deguchi
- Organizer
  11th Cerebral Vascular Biology International Conference
- Place of Presentation
  パリ
- Year and Date
  2015-07-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08080
[Presentation] Blood-to-brain transport of apomorphine enantiomers by proton-coupled organic cation antiporter at the blood-brain barrier2015
- Author(s)
  Takashi Okura, Kei Higuchi, Atsushi Kitamura, Yoshiharu Deguchi
- Organizer
  11th Cerebral Vascular Biology International Conference
- Place of Presentation
  パリ
- Year and Date
  2015-07-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08080
[Presentation] Involvement of functionally diverse proton-coupled organic cation antiporter in blood-brain barrier transport of memantine2015
- Author(s)
  Higuchi K, Kitamura A, Okura T, Deguchi Y
- Organizer
  11th International Conference on Cerebral Vascular Biology
- Place of Presentation
  Paris (France)
- Year and Date
  2015-07-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] アポモルヒネの高い脳移行性を担う血液脳関門輸送のインビボ解析2014
- Author(s)
  黄倉　崇、佐藤樹夏、樋口　慧、北村　敦、柄谷礼人、久保敬史、小林俊生、櫻庭美菜子、出口芳春
- Organizer
  第58回薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] hCMEC/D3細胞を用いたカクテル法によるH+/有機カチオン交換輸送体基質探索の基礎的検討2014
- Author(s)
  樋口　慧、北村　敦、黄倉　崇、出口芳春
- Organizer
  日本薬学会第13４年会
- Place of Presentation
  熊本大学（熊本）
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] 脳マイクロダイアリシス法による薬物カクテルの脳移行性評価2014
- Author(s)
  北村敦、黒澤俊樹、樋口慧、黄倉崇、福島貴人、祖父江佳奈、出口芳春
- Organizer
  第58回薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] Slc6a13を介した胎盤へのヒポタウリン供給が示す抗酸化作用.2013
- Author(s)
  杉田友紀、Mariam Duereh、樋口慧、西村友宏、崔吉道、登美斉俊、中島恵美.
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790171
[Presentation] ヒト血液脳関門におけるアポモルヒネのプロトン交換輸送機構2013
- Author(s)
  黄倉　崇、樋口慧、出口芳春
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインク愛知（名古屋）
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] トランスポーターを利用した薬物の脳移行　－ヒト血液脳関門におけるメマンチンの輸送機構解析－2013
- Author(s)
  樋口　慧、黄倉　崇、出口芳春
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  ウインク愛知（名古屋）
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] ヒト血液脳関門細胞hCMEC/D3におけるメマンチンの輸送特性2013
- Author(s)
  樋口　慧、北村敦、黄倉　崇、出口芳春
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] Slc6a13を介した胎盤へのヒポタウリン供給が示す抗酸化作用2013
- Author(s)
  杉田友紀、Mariam Duereh、樋口慧、西村友宏、崔吉道、登美斉俊、中島恵美
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790171
[Presentation] EzrinがSlc6a13の細胞内局在および輸送機能に与える影響.2012
- Author(s)
  荒木光, 樋口慧, 西村友宏, 崔吉道, 登美斉俊, 中島恵美.
- Organizer
  第7回トランスポーター研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790171
[Presentation] EzrinがSlc6a13の細胞内局在および輸送機能に与える影響2012
- Author(s)
  荒木光,樋口慧,西村友宏,崔吉道,登美斉俊,中島恵美
- Organizer
  第7回トランスポーター研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790171
[Presentation] Effect of ezrin on cellular localization and transport function of Slc6a132012
- Author(s)
  Araki H, Higuchi K, Nishimura T, Sai Y, Tomi M, Nakashima E
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790171
[Presentation] ヒポタウリンのヒドロキシラジカル消去活性による胎盤細胞保護効果2012
- Author(s)
  Mariam Duereh、西村友宏、杉田友紀、樋口慧、登美斉俊、中島恵美
- Organizer
  日本動物実験代替法学会第25回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790171
[Presentation] ヒト脳毛細血管内皮細胞株 hCMEC/D3 を用いたカチオン性薬物のヒト血液脳関門透過性予測の試み2012
- Author(s)
  黄倉崇、樋口慧、出口芳春ら
- Organizer
  日本動物実験代替学会第25回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590144
[Presentation] ヒポウリタンによるヒドロキシラジカルからの胎盤細胞保護効果2012
- Author(s)
  Mariam Duereh,樋口慧,杉田友紀,西村友宏,登美斉俊,中島恵美
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790171
[Presentation] ヒポウリタンによるヒドロキシラジカルからの胎盤細胞保護効果.2012
- Author(s)
  Mariam Duereh, 樋口慧, 杉田友紀, 西村友宏, 登美斉俊, 中島恵美.
- Organizer
  日本薬剤学会第27年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790171
[Presentation] Effect of ezrin on cellular localization and transport function of Slc6a13.2012
- Author(s)
  Araki H, Higuchi K, Nishimura T, Sai Y, Tomi M, Nakashima E.
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790171
[Presentation] ヒト脳毛細血管内皮細胞株hCMEC/D3を用いたカチオン性薬物のヒト血液脳関門透過性予測の試み2012
- Author(s)
  黄倉崇、下村慶太、樋口　慧、Pierre-Oliver Couraud、出口芳春
- Organizer
  日本動物実験代替学会第25回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590144
[Presentation] ヒポタウリンのヒドロキシラジカル消去活性による胎盤細胞保護効果.2012
- Author(s)
  Mariam Duereh、西村友宏、杉田友紀、樋口慧、登美斉俊、中島恵美.
- Organizer
  日本動物実験代替法学会第25回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790171
[Presentation] ヒト血液脳関門のトラマドール輸送における
- Author(s)
  北村　敦、樋口　慧、黄倉　崇、出口　芳春
- Organizer
  第57回日本薬学会関東支部大会
- Place of Presentation
  帝京大学板橋キャンパス（東京）
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] IN VIVO AND IN VITRO TRANSPORT OF APOMORPHINE ENANTIOMERS ACROSS THE BLOOD-BRAIN BARRIER
- Author(s)
  Kitamura A, Higuchi K, Okura T, Deguchi Y
- Organizer
  19th North American ISSX Meeting and 29th JSSX Annual Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] 脳マイクロダイアリシス法を用いたカクテル投与による薬物の脳移行性評価
- Author(s)
  北村敦、樋口慧、黄倉崇、祖父江佳奈、福島貴人、出口芳春
- Organizer
  日本薬剤学会第29年回
- Place of Presentation
  埼玉
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] A proton-coupled organic cation antiporter mediated transport of apomorphine in human brain capillary endothelial cell line hCMEC/D3
- Author(s)
  Takashi Okura, Kei Higuchi, Atsushi Kitamura, Yoshiharu Deguchi
- Organizer
  第7回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東北大学片平キャンパス(仙台）
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] TRANSPORT CHARACTERISTICS OF TRAMADOL AT THE BLOOD-BRAIN BARRIER
- Author(s)
  Deguchi Y, Kitamura A, Higuchi K, Okura T
- Organizer
  19th North American ISSX Meeting and 29th JSSX Annual Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-25460199
[Presentation] プロトン交換輸送体によるアポモルヒネのヒト血液脳関門輸送
- Author(s)
  黄倉　崇、樋口　慧、北村敦、出口芳春
- Organizer
  日本薬物動態学会第28年会
- Place of Presentation
  タワーホール船堀（東京
- Data Source
  KAKENHI-PROJECT-25460199
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1. Inoue Katsuhisa (50315892)

# of Collaborated Projects: 6 results

# of Collaborated Products: 37 results
2. Kishimoto Hisanao (80723600)

# of Collaborated Projects: 6 results

# of Collaborated Products: 37 results
3. DEGUCHI Yoshiharu (40254255)

# of Collaborated Projects: 4 results

# of Collaborated Products: 40 results
4. OKURA Takashi (80326123)

# of Collaborated Projects: 4 results

# of Collaborated Products: 30 results
5. KATO Sayaka (70505940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HOSOYAMADA MAKOTO (00291659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 平田圭一 (80424852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中谷絵理子 (90803916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Kawabata Kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. Yamaguchi Tomoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. Kusuhara Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. SHIRASAKA Yoshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. 飯笹久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 丸山哲夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Higuchi Kei 樋口 慧

HIGUCHI Kei 樋口 慧

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医薬品の吸収改善を目指すオリゴペプチドトランスポーターEOPTsの分子制御機構解明Principal Investigator

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Identification of novel equilibrative oligopeptide transporters that may regulate drug absorption in the gastrointestinal tractPrincipal Investigator

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塩基性薬物輸送を担う血液脳関門オーファントランスポーターの機能解明Principal Investigator

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Mechanism of hypotaurine transport by Slc6a13 for oxidative stress defensePrincipal Investigator

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[Journal Article] The Use of Carboxyfluorescein Reveals the Transport Function of MCT6/SLC16A5 Associated with CD147 as a Chloride-Sensitive Organic Anion Transporter in Mammalian Cells2024

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[Journal Article] Monocarboxylate Transporter 13 (MCT13/SLC16A13) Functions as a Novel Plasma Membrane Oligopeptide Transporter2023

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[Journal Article] Macrolide and Ketolide Antibiotics Inhibit the Cytotoxic Effect of Trastuzumab Emtansine in HER2-Positive Breast Cancer Cells: Implication of a Potential Drug-ADC Interaction in Cancer Chemotherapy2023

Higuchi Kei 樋口慧

HIGUCHI Kei 樋口慧