Hosoyamada Makoto 細山田真

… Alternative Names

HOSOYAMADA Makoto 細山田真

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Researcher Number	00291659
Other IDs
Affiliation (Current)	2022: 帝京大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2011 – 2022: 帝京大学, 薬学部, 教授 2010: 慶應大学, 薬学部, 准教授 2008 – 2010: Keio University, 薬学部, 准教授 2007: Kyoritsu University of Pharmacy, Pharmaootherapeutics, Associate Professor 2006: Kyorin University, School of Medicine, Instructor … More 2005 – 2006: 共立薬科大学, 薬学部, 助教授 2000 – 2004: 杏林大学, 医学部, 講師 2002 – 2003: 杏林大学, 医学部・薬理学教室, 講師 1997 – 2000: 杏林大学, 医学部, 助手 1998 – 1999: 杏林大学, 医学部・薬理学教室, 助手 Less
Review Section/Research Field	Principal Investigator General pharmacology / General pharmacology / Kidney internal medicine / Applied pharmacology / Metabolomics / Kidney internal medicine / Basic Section 53040:Nephrology-related Except Principal Investigator 応用薬理学・医療系薬学 / General pharmacology / Kidney internal medicine … More / Kidney internal medicine / Otorhinolaryngology / Pharmacology in pharmacy / Pediatrics / Environmental pharmacy / General pharmacology / Medical pharmacy / Basic Section 53040:Nephrology-related Less
Keywords	Principal Investigator トランスポーター / 腎臓 / 尿酸 / 高尿酸血症 / hOAT1 / 中性アミノ酸 / cDNAクローニング / ASCT2 / ラット / SNPs … More / プロベネシド / ベンズブロマロン / ピラジンカルボン酸 / マウスOAT1 / プロモーター / CD4^+細胞 / ゲルシフトアッセイ / 薬物治療学 / 病態モデル / 病態モデル動物 / 腎臟 / 病態モドル動物 / 有機酸 / 培養細胞 / transporter / organic anion / culture cell / kidney / 有機アニオン輸送 / 薬物輸送 / 有機カチオン輸送 / 利尿薬 / 抗不整脈薬 / Organic anion transport / Drug transport / Kidney / Organic cation transport / Diuretics / Anti-arrhythmia / ノックアウトマウス / Urate / Transporter / Knockout mice / キサンチンオキシドレダクターゼ / ウリカーゼ / ヒポキサンチンホスホリボシルトランスフェラーゼ / 酵素 / 核酸 / 運動後急性腎障害 … More Except Principal Investigator トランスポーター / URAT1 / 尿酸 / kidney / 有機アニオン / 有機アニオントランスポーター / organic anion transporter / ジカルボン酸 / ジカルボン酸トランスポーター / 高尿酸血症 / 尿酸トランスポーター / パラアミノ馬尿酸 / エストロン硫酸 / 腎臓 / pharmacokinetics / transporter / BAT1 / rBAT / 近位尿細管直部 / 近位尿細管中間部 / 尿酸輸送体 / 痛風 / ABCG2 / 低尿酸血症 / purinoceptor / intracellular calcium / ATP / proximal tubules / アミノ酸 / オクラトキシンA / 薬物輸送 / organic anion / hOAT1 / drug transporter / liver / brain / organic anion transporter1 / organic anion transporter2 / organic anion transporter3 / knockout mouse / 血液脳関門 / Organic anion transporter / Uric acid / 近位尿細管性アシドーシス / シスチン尿症 / 重炭酸イオン共輸送体 / 尿路結石 / 遺伝因子 / 環境因子 / ナトリウム / renal stones / genetic factor / PDZK1 / ベンズブロマロン / プロスタグランジン / β-ラクタム抗生物質 / 腎内輸送 / 腎内蓄積 / 不死化細胞 / 近位尿細管終末部 / 髄質外層集合管 / シスプラチン / アポトーシス / 陰イオン有機酸輸送 / デキサメサゾン / 多選択性トランスポーター / 交換輸送 / 鼻粘膜 / LAT1 / LAT2 / OAT1 / OAT3 / OAT4 / 多選択性有機アニオントランスポーター / モノカルボン酸トランスポーター / human OAT1 / 腎臓学 / 運動後急性腎不全 / 腎外排泄低下型高尿酸血症 / 排泄低下型高尿酸血症 / 産生過剰型高尿酸血症 / 発症年齢 / 腎負荷型高尿酸血症 / GLUT9 / URATv1 / nephron segment / mesangial cell / purinoreceptor / protein kinase C / phosphorylation / nephron / calcium / P_<2Y> / P_<2U> / 尿細管 / 細胞内カルシウム / desensitization / nephron segments / mesangial cells / 膜輸送 / 酸化的ストレス / システイン / シスチン / 中枢神経 / 分子薬理学 / 神経細胞 / クローニング / グリオーマ / Transporter / Membrane transport / amino acids / oxidative stress / cystine / cysteine / Central nervous system / Molewlar Pharmawlogy / 有機カチオントランスポーター / カルニチントランスポーター / 多選択性基質認識 / para-amino hippurate / estron sulfate / ochratoxin A / organic cation transporter / carnitine transporter / multispecific substrate recognition / URATE / TRANSPORTER / 有機カチオン / 薬物動態 / 血液・組織関門 / 腎 / 分子クローニング / placenta / cloning / organic cation / drug transport / blood-brain barrier / molecular cloning / gene targetting / gene targeting / 薬物トランスポーター / 有機陰イオントランスポーター / LATファミリー / 補助因子 / ヘテロダイマー / 芳香族アミノ酸 / トリヨードサイロニン / L-ドーパ / メチル水銀システイン抱合体 / 有機陰イオントランスポーター(OAT) / OATファミリー / サリチル酸 / システイン抱合体 / Drug transporter / LAT family / Associating protein / Heterocllimer / Aromatic amino acid / Triiodethyronie / L-Dopa / アニオントランスポーター / カチオントランスポーター / カルニチン / 特発性腎性低尿酸血症 / 一塩基変異遺伝子 / 精巣上体 / セルトリ細胞 / 胎盤 / 突発性腎性低尿酸血症 / 一塩基変異遺伝子多型 / イントロン / エクソン / デヒドロエピアンドロステロン硫酸 / Anion transporter / Cation transporter / Carnitine / Idopathic renal hypouricemia / SNP / Epididymis / Sertoli cell / Na+ / 近位尿再管性アシドーシス / BATl / rBATl / Proximal tubular acidosis / Cystinuria / Sodium-bicarbonate cotransporter / environmental factor / 家族性腎性低尿酸血症 / ゲノム / 特発性低尿酸血症 / イーストツーハイブリド法 / PDZK 1 / ベンズプロマロン / Familial renal hypouricemia / Hyperuricemia / gout / ポドシン / ネフリン / スリット膜 / 蛋白輸送 / ミスセンス変異 / 蛋白細胞内輸送 / ネフローゼ / Podocin / Nephrin / 細胞内蛋白輸送 / podocin / nephrin / slit membrane / protein transport / missense mutant / 腎性低尿酸血症 / SLC22A12 / プロベネシド / SLCA22A12 / Urate / Renal hypouricemia / 環境 / 重金属 / 毒性 / environment / heavy metals / toxicology / 薬理学 / 輸送体 / 膜蛋白質 / 蛋白質間相互作用 / 細胞膜移行 / 活性制御 / 足場タンパク質 / Pharmacology / membrane protein / Protein-protein interaction / amino acid / membrane targeting / Functional regulation / scaffold protein / 起源 / 動態 / Kidney / Hypouricemia / Oriein / ヒト脳移行性 / 有機カチオン性薬物 / ヒト血液脳関門モデル細胞 / 循環培養システム / フロー培養システム / 血液脳関門モデル細胞 / GLUT9/SLC2A9 / プリン代謝 / 腎不全 / 腎毒性 / プリン代謝関連物質 / HPRT / キサンチンオキシドレダクターゼ / ウリカーゼ / ノックアウトマウス Less

Elucidation of the mechanism of exercise-induced acute kidney injury associated with renal hypouricemia type 1 model micePrincipal Investigator
- Principal Investigator
  
  細山田真
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Teikyo University
Sutudy for substances responsible for renal failure death in xanthine oxidoreductase knockout mice
- Principal Investigator
  
  WATANABE Tamaki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Teikyo University
Generation of human urate metabolism complete model mice by suppressing xanthine dehydrogenase expressionPrincipal Investigator
- Principal Investigator
  
  Hosoyamada Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Teikyo University
Studies on androgenic and angiotensin system inhibitors for inhibiting the progression of chronic kidney disease
- Principal Investigator
  
  WATANABE Tamaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Teikyo University
Elucidation of environmental factors involved in the onset of hyperuricemia using complete model animals of human uric acid metabolismPrincipal Investigator
- Principal Investigator
  
  Hosoyamada Makoto
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Teikyo University
Analysis of genes influencing serum urate levels
- Principal Investigator
  
  Ichida Kimiyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of a novel experimental evaluation method for predicting the drug delivery to the brain in human
- Principal Investigator
  
  DEGUCHI YOSHIHARU
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Teikyo University
Identification and analysis of genes influencing serum uric acid levels
- Principal Investigator
  
  ICHIDA Kimiyoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo University of Pharmacy and Life Science
Elucidation of the pathogenic mechanism of hyperuricemia in obesity and metabolic syndromePrincipal Investigator
- Principal Investigator
  
  HOSOYAMADA Makoto
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Teikyo University
Production of disease model mice for the drug screening of familial juvenile hyperuricemic nephropathyPrincipal Investigator
- Principal Investigator
  
  HOSOYAMADA Makoto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Keio University
Elucidation of mechanism for exercise-induced acute renal failure in urate transporter deficient mice
- Principal Investigator
  
  ICHIDA Kimiyoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo University of Pharmacy and Life Science
Analysis of the mechanism of cadmium nephropathy based on, cadmium kinetics
- Principal Investigator
  
  TOSHIAKI Shibasaki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Kyoritsu University of Pharmacy
Study on_the protein-protein interaction regulating the function of amino acid transporters
- Principal Investigator
  
  KANAI Yoshikatsu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Analysis of the onset mechanism of acute renal failure post exercise using urate transporter knockout micePrincipal Investigator
- Principal Investigator
  
  HOSOYAMADA Makoto
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyoritsu University of Pharmacy
Genetic analysis for uric acid handling in the kidney
- Principal Investigator
  
  KIMIYASHI Ichida
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Jikei University School of Medicine
Study of drug transport mechanism by renal organicion transporters and their clinical significancePrincipal Investigator
- Principal Investigator
  
  HOSOYAMADA Makoto, 武田理夫
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
Development of novel anti-uricosuric agents based on the genomic strategy.
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Protein analysis of steroid resistant congenital nephrotic syndrome gene: podocin
- Principal Investigator
  
  YAN Kunimasa
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyorin University
Genetic analysis for mechanism of underexcretion type hyperuricemia
- Principal Investigator
  
  ICHIDA Kimiyoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Jikei University School of Medicine
ヒト有機アニオントランスポーターhOAT1におけるプロモーター解析Principal Investigator
- Principal Investigator
  
  細山田真
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Genetic Abnormality of Renal Proximal Tubule-Specific Transporters as Causes of Sudden Death Syndrome in South-Eastern Asia
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
Identification of transporter genes regulating systemic kinetics of drugs and foreign compounds and their genetic polymorphism
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
ヒト尿酸トフンスポーター遺伝子のクローニングと機能解析Principal Investigator
- Principal Investigator
  
  細山田真
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Cloning of transporters for anionic drugs and the application to pharmacokinetic analysis
- Principal Investigator
  
  KANAI Yoshikatsu, 関根孝司
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
FUNCTIONAL ANALYSIS OF THE ANIONIC DRUG TRANSPORTERS USING KNOCKOUT MICE
- Principal Investigator
  
  INATOMI Jun, 車碩鎬
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Molecular mechanisms of drug transport across cell membrane
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
鼻粘膜薬物吸収におけるトランスポーターの役割に関する研究
- Principal Investigator
  
  長谷川誠
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kyorin University
Development of artificial kidney hybridized with human organic anion transporter expressed cellsPrincipal Investigator
- Principal Investigator
  
  HOSOYAMDA Makoto
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
ISOLATION AND ANALYSIS OF URATE TRANSPORTER OF HUMAN PROXIMAL TUBULE
- Principal Investigator
  
  ICHIDA Kimiyoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  JIKEI UNIVERSITY SCHOOL OF MEDICINE
有機アニオン輸送の細胞内分子機序
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyorin University
腎特異性グルタミン酸トランスポーターの遺伝子クローニングと機能特性Principal Investigator
- Principal Investigator
  
  細山田真
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
New roprorective roles of amino acid transporrers
- Principal Investigator
  
  KANAI Yoshikatdu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Molecular cloning and functional expression of kidney-specific organic anionic drug transporters
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University School of Medicine
The study toward the development of specific agonist and antagonist for the purinergic receptors in the kidney
- Principal Investigator
  
  SEKINE Takashi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
腎毒性予測法の開発
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University

[Journal Article] SLC23A3 is a renal hypoxanthine transporter2022
- Author(s)
  Makoto Hosoyamada, Naoko H. Tomioka, Tamaki Watanabe, Nobuhiro Yasuno, Shunya Uchida, Shigeru Shibata
- Journal Title
  
  Nucleosides, Nucleotides & Nucleic Acids
  
  Volume: - Pages: 1-8
- DOI
  10.1080/15257770.2022.2028826
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08222, KAKENHI-PROJECT-20K11598
[Journal Article] Perfecting a high hypoxanthine phosphoribosyltransferase activity-uricase KO mice to test the effects of purine- and non-purine-type xanthine dehydrogenase (XDH) inhibitors.2020
- Author(s)
  Hosoya T, Uchida S, Shibata S, Tomioka NH, Hosoyamada M.
- Journal Title
  
  Br J Pharmacol.
  
  Volume: 177(10) Pages: 2274-2285
- DOI
  10.1111/bph.14978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08605
[Journal Article] Renoprotective effect of topiroxostat via antioxidant activity in puromycin aminonucleoside nephrosis rats2017
- Author(s)
  Kawamorita Y, Shiraishi T, Tamura Y, Kumagai T, Shibata S, Fujigaki Y, Hosoyamada M, Nakagawa T, Uchida S.
- Journal Title
  
  Physiological Reports
  
  Volume: 5(15)
- DOI
  10.14814/phy2.13358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00871, KAKENHI-PROJECT-17K08605
[Journal Article] Insulin stimulates uric acid reabsorption via regulating urate transporter 1 and ATP-binding cassette subfamily G member 22017
- Author(s)
  Toyoki D, Shibata S, Kuribayashi-Okuma E, Xu N, Ishizawa K, Hosoyamada M, Uchida S.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 313(3) Pages: 826-834
- DOI
  10.1152/ajprenal.00012.2017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00871, KAKENHI-PROJECT-17K08605, KAKENHI-PROJECT-15H04837
[Journal Article] Podocyte Injury and Albuminuria in Experimental Hyperuricemic Model Rats2017
- Author(s)
  Asakawa S, Shibata S, Morimoto C, Shiraishi T, Nakamura T, Tamura Y, Kumagai T, Hosoyamada M, Uchida S.
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 3759153 Pages: 1-14
- DOI
  10.1155/2017/3759153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04837, KAKENHI-PROJECT-17K08605
[Journal Article] The mechanism of false in vitro elevation of uric acid level in mouse blood.2016
- Author(s)
  Watanabe T, Tomioka NH, Watanabe S, Suzuki Y, Tsuchiya M, Hosoyamada M
- Journal Title
  
  Biol. Pharm. Bull.
- NAID
  130005160780
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460347
[Journal Article] The Mechanism of False <i>in Vitro</i> Elevation of Uric Acid Level in Mouse Blood2016
- Author(s)
  Tamaki Watanabe, Naoko H. Tomioka, Shigekazu Watanabe, Yoshihiko Suzuki, Masao Tsuchiya, Makoto Hosoyamada
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 7 Issue: 7 Pages: 1081-1084
- DOI
  10.1248/bpb.b15-01046
- NAID
  130005160780
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460105
[Journal Article] The mechanism of false in vitro elevation of uric acid level in mouse blood2016
- Author(s)
  Tamaki Watanabe, Naoko H. Tomioka, Shigekazu Watanabe, Yoshihiko Suzuki, Masao Tsuchiya, Makoto Hosoyamada
- Journal Title
  
  Biological & pharmaceutical bulletin
  
  Volume: in press
- NAID
  130005160780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460105
[Journal Article] Urat1-Uox double knockout mice are experimental animal models of renal hypouricemia and exercise-induced acute kidney injury.Urat1-Uox double knockout mice are experimental animal models of renal hypouricemia and exercise-induced acute kidney injury.2016
- Author(s)
  Hosoyamada M, Tsurumi Y, Hirano H, Tomioka NH, Sekine Y, Morisaki T, Uchida S.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids.
  
  Volume: 35 Pages: 543-549
- DOI
  10.1080/15257770.2016.1143559
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460347
[Journal Article] Apoptosis induced by an uromodulin mutant C112Y and its suppression by topiroxostat.2015
- Author(s)
  Utami SB, Mahati E, Li P, Maharani N, Ikeda N, Bahrudin U, Munemura C, Hosoyamada M, Yamamoto Y, Yoshida A, Nakayama Y, Higaki K, Nanba E, Ninomiya H, Shirayoshi Y, Ichida K, Yamamoto K, Hosoya T, Hisatome I.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 00 Pages: 000-0
- DOI
  10.1007/s10157-014-1032-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460347, KAKENHI-PROJECT-26501003
[Journal Article] Identification of a hypouricemia patient with SLC2A9 R380W, a pathogenic mutation for renal hypouricemia type 2.2014
- Author(s)
  Chiba T, Matsuo H, Nagamori S, Nakayama A, Kawamura Y, Shimizu S, Sakiyama M, Hosoyamada M, Kawai S, Okada R, Hamajima N, Kanai Y, Shinomiya N.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids.
  
  Volume: 33 Pages: 261-5
- DOI
  10.1080/15257770.2013.857781
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-26460347
[Journal Article] False in vitro and in vivo elevations of uric acid levels in mouse blood.2014
- Author(s)
  Watanabe T, Tomioka NH, Watanabe S, Tsuchiya M, Hosoyamada M.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids.
  
  Volume: 33 Pages: 192-8
- DOI
  10.1080/15257770.2013.865742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460347
[Journal Article] False in vitro and in vivo elevations of uric acid levels in mouse blood.2014
- Author(s)
  Watanabe T, Tomioka NH, Watanabe S, Tsuchiya M, Hosoyamada M
- Journal Title
  
  Nucleosides, nucleotides & nucleic acids
  
  Volume: 33 Pages: 192-198
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460105
[Journal Article] False in vitro and in vivo elevations of uric acid levels in mouse blood.2014
- Author(s)
  Watanabe T, Tomioka NH, Watanabe S, Tsuchiya M, Hosoyamada M
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591340
[Journal Article] Common dysfunctional variants in ABCG2 are a major cause of early-onset gout2013
- Author(s)
  Matsuo, H.　Ichida, K.　Takada, T. et al.
- Journal Title
  
  Sci Rep.
  
  Volume: 3：2014 Pages: 2014-2014
- DOI
  10.1038/srep02014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23591205, KAKENHI-PROJECT-23591340, KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-24390217, KAKENHI-PROJECT-25293145, KAKENHI-PROJECT-25670307
[Journal Article] Macrophage migration inhibitory factor is a possible candidate for the induction of microalbuminuria in diabetic db/db mice.2013
- Author(s)
  Watanabe T, Tomioka NH, Doshi M, Watanabe S, Tsuchiya M, Hosoyamada M.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: 36(5) Pages: 741-747
- NAID
  130003361408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591340
[Journal Article] Ependymal cells of the mouse brain express urate transporter 1 (URAT1).2013
- Author(s)
  Tomioka NH, Nakamura M, Doshi M, et al
- Journal Title
  
  Fluids and barriers of the CNS
  
  Volume: 10 Pages: 31-31
- DOI
  10.1186/2045-8118-10-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591205, KAKENHI-PROJECT-23591340, KAKENHI-PROJECT-24790051
[Journal Article] Common dys-functional variants in ABCG2 are a major cause of early-onset gout2013
- Author(s)
  Matsuo H, Ichida K, Takada T, Nakayama A, Nakashima H, Nakamura T, Kawamura Y, Takada Y, Yamamoto K, Inoue H, Oikawa Y, Naito M, Hishida A, Wakai K, Okada C, Shimizu S, Sakiyama M, Chiba T, Ogata H, Niwa K, Hosoyamada M, Mori A, Hamajima N, Suzuki H, Kanai Y, Sakurai Y, Hosoya T, Shimizu T, Shinomiya N
- Journal Title
  
  Sci Rep
  
  Volume: 3 Pages: 2014-2014
- Data Source
  KAKENHI-PROJECT-23591340
[Journal Article] Macrophage migration inhibitory factor is a possible candidate for the induction of microalbuminuria in diabetic db/db mice2013
- Author(s)
  Watanabe T, Tomioka NH, Doshi M, Watanabe S, Tsuchiya M, Hosoyamada M
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 36(5) Pages: 741-747
- NAID
  130003361408
- Data Source
  KAKENHI-PROJECT-23591340
[Journal Article] Ependymal cells of the mouse brain express urate transporter 1 (URAT1)2013
- Author(s)
  Tomioka NH, Nakamura M, Doshi M, Deguchi Y, Ichida K, Morisaki T, Hosoyamada M
- Journal Title
  
  Fluids Barriers CNS
  
  Volume: 10(1) Pages: 31-31
- Data Source
  KAKENHI-PROJECT-23591205
[Journal Article] Common dysfunctional variants in ABCG2 are a major cause of early-onset gout2013
- Author(s)
  Matsuo H, Ichida K, Takada T, Nakayama A, Nakashima H, Nakamura T, Kawamura Y, Takada Y, Yamamoto K, Inoue H, Oikawa Y, Naito M, Hishida A, Wakai K, Okada C, Shimizu S, Sakiyama M, Chiba T, Ogata H, Niwa K, Hosoyamada M, Mori A, Hamajima N, Suzuki H, Kanai Y, Sakurai Y, Hosoya T, Shimizu T, Shinomiya N
- Journal Title
  
  Sci Rep
  
  Volume: 3 Pages: 2014-2014
- Data Source
  KAKENHI-PROJECT-23591205
[Journal Article] ウリカーゼ融合タンパク質を用いた細胞内尿酸検出法の開発2013
- Author(s)
  中村　真希子、細山田真, 市田公美
- Journal Title
  
  痛風と核酸代謝
  
  Volume: ３７ Pages: 93-101
- NAID
  130003388381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591205
[Journal Article] Ependymal cells of the mouse brain express urate transporter 1 (URAT1)2013
- Author(s)
  Tomioka NH, Nakamura M, Doshi M, Deguchi Y, Ichida K, Morisaki T, Hosoyamada M
- Journal Title
  
  Fluids Barriers CNS
  
  Volume: 10(1) Pages: 31-31
- Data Source
  KAKENHI-PROJECT-23591340
[Journal Article] Decreased extra-renal urate excretion is a common cause of hyperuricemia2012
- Author(s)
  Ichida K, Matsuo H, Takada T, Nakayama A, Murakami K, Shimizu T, Yamanashi Y, Kasuga H, Nakashima H, Nakamura T, Takada Y, Kawamura Y, Inoue H, Okada C, Utsumi Y, Ikebuchi Y, Ito K, Nakamura M, Shinohara Y, Hosoyamada M, Sakurai Y, Shinomiya N, Hosoya T, Suzuki H
- Journal Title
  
  Nat Commun
  
  Volume: 3 Pages: 764-770
- Data Source
  KAKENHI-PROJECT-23591340
[Journal Article] Decreased Extra−renal Urate Excretion is a Common Cause of Hyperuricemia.2012
- Author(s)
  Kimiyoshi Ichida, Hirotaka Matsuo, Tappei Takada, et al (Hiroshi Suzuki)
- Journal Title
  
  Nature Communications
  
  Volume: 3 Pages: 1-7
- DOI
  10.1038/ncomms1756
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22136001, KAKENHI-PROJECT-22689021, KAKENHI-PROJECT-23300365, KAKENHI-PROJECT-23591205, KAKENHI-PROJECT-23591340, KAKENHI-PROJECT-23659339, KAKENHI-PROJECT-23689008, KAKENHI-PROJECT-24790051, KAKENHI-PLANNED-22136015
[Journal Article] Decreased extra-renal urate excretion is a common cause of hyperuricemia2012
- Author(s)
  Ichida K, Matsuo H, Takada T, Nakayama A, Murakami K, Shimizu T, Yamanashi Y, Kasuga H, Nakashima H, Nakamura T, Takada Y, Kawamura Y, Inoue H, Okada C, Utsumi Y, Ikebuchi Y, Ito K, Nakamura M, Shinohara Y, Hosoyamada M, Sakurai Y, Shinomiya N, Hosoya T, Suzuki H
- Journal Title
  
  Nat Commun
  
  Volume: 3 Pages: 764-764
- Data Source
  KAKENHI-PROJECT-23591205
[Journal Article] The increased protein level of URAT1 was observed in obesity/metabolic syndrome model mice.2011
- Author(s)
  Doshi M, Takiue Y, Saito H, Hosoyamada M.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids.
  
  Volume: 30(12): Pages: 1290-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591340
[Journal Article] Enhancement of Androgen Action in the Kidneys of Transgenic Mice Harboring the Mutant Human UMOD Gene.2011
- Author(s)
  Takiue Y, Hosoyamada M
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 115 Pages: 383-389
- NAID
  10029892818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590547
[Journal Article] The increased protein level of URAT1 was observed in obesity/metabolic syndrome model mice2011
- Author(s)
  Doshi M, Takiue Y, Saito H, Hosoyamada M
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 30(12) Pages: 1290-4
- Data Source
  KAKENHI-PROJECT-23591340
[Journal Article] Enhancement of Androgen Action in the Kidneys of Transgenic Mice Harboring the Mutant Human UMOD Gene.2011
- Author(s)
  Takiue Y, Hosoyamada M, Kimura M, Saito H
- Journal Title
  
  J Pharmacol Sci. 115(3)
  
  Pages: 383-9
- NAID
  10029892818
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590547
[Journal Article] The effect of female hormones upon urate transport systems in the mouse kidney.2011
- Author(s)
  Takiue Y, Hosoyamada M, Kimura M, Saito H
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids. 30(2)
  
  Pages: 113-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590547
[Journal Article] Establishment and analysis of Slc22a12(Urat1)knockout mouse2010
- Author(s)
  Hosoyamada M
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 29(4-6)
  
  Pages: 314-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590547
[Journal Article] Establishment and analysis of SLC22A12(URAT1)knockout mouse.2010
- Author(s)
  Hosoyamada M
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 29 Pages: 314-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590965
[Journal Article] The effect of testosterone upon the urate reabsorptive transport system in mouse kidney.2010
- Author(s)
  Hosoyamada M
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 29 Pages: 574-579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590547
[Journal Article] The effect of testosterone upon the urate reabsorptive transport system in mouse kidney.2010
- Author(s)
  Hosoyamada M, Takiue Y, Shibasaki T, Saito H
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids. 29(7)
  
  Pages: 574-579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590547
[Journal Article] Development of LC-MS method for detection of mutant uromodulin protein.2010
- Author(s)
  Yasuda M, Kaneko K, Hachisu H, Ochiai M, Yamanobe T, Mawatari K, Nakagomi K, Minoura N, Hosoyamada M
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids. 29(4-6)
  
  Pages: 515-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590547
[Journal Article] Establishment and analysis of SLC22A12 (URAT1) knockout mouse.2010
- Author(s)
  Hosoyamada M, Takiue Y, Morisaki H, Cheng J, Ikawa M, Okabe M, Morisaki T, Ichida K, Hosoya T, Shibasaki T
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids. 29(4-6)
  
  Pages: 314-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590547
[Journal Article] Establishment and analysis of SLC22A12 (URAT1) knockout mouse2010
- Author(s)
  Hosoyamada M, Takiue Y, Morisaki H, et al
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 29
  
  Pages: 314-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590965
[Journal Article] Uricosuric action of losartan via the inhibition of urate transporter 1 (URAT 1) in hypertensive patients2008
- Author(s)
  Hamada T, Ichida K, Hosoyamada M, et al
- Journal Title
  
  Am J Hypertens 21
  
  Pages: 1157-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590965
[Journal Article] Normal cadmium uptake in microcytic anemia mk/mk mice suggests that DMT1 is not theonly cadmium transporter in vivo.2008
- Author(s)
  Tomohito Suzuki, Kanae Momoi, Makoto Hosoyamada, Masaki Kimura, Toshiaki Shibasaki
- Journal Title
  
  Toxicology and Applied Pharmacology 227(3)
  
  Pages: 462-467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590106
[Journal Article] Changes of cadmium concentration and expressions of candidates for the cadmium transporter genes in intestine, in short term low dose exposure2008
- Author(s)
  Tomohito, Suzuki, Makoto, Hosoyamada, Makoto, Sato, Yoko, Namikoshi, Kanae, Momoi, Masaki, Kimura, Toshiaki, Shibasaki
- Journal Title
  
  The Journal of Kyoritsu University of Pharmacy 4
  
  Pages: 1-8
- NAID
  120000801789
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590106
[Journal Article] Progressive accumulation of intrinsic mouse uromodulin in the kidneys of transgenic mice harboring the mutant human uromodulin gene.2008
- Author(s)
  Takiue Y, Hosoyamada M, Yokoo T, Kimura M, Shibasaki T
- Journal Title
  
  Biol Pharm Bull 31
  
  Pages: 405-11
- NAID
  110006623065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590547
[Journal Article] Changes of cadmium concentration and expressions of candidates for the cadmium transporter genes in intestine, in short term low dose exposure.2008
- Author(s)
  Tomohito Suzuki, Makoto Hosoyamada, Makoto Sato, Yoko Namikoshi, Kanae Momoi, Masaki
- Journal Title
  
  The Journal of Kyoritsu University of Pharmacy 4
  
  Pages: 1-8
- NAID
  120000801789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590106
[Journal Article] Normal cadmium uptake in microcytic anemia mk/mk mice suggests that DMT1 is not the only cadmium transporter in vivo2008
- Author(s)
  Tomohito Suzuki, Kanae Momoi, Makoto Hosoyamada, Masaki Kimura, Toshiaki Shibasaki
- Journal Title
  
  Toxicology and Applied Pharmacology 227(3)
  
  Pages: 462-467
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590106
[Journal Article] Production and characterization of transgenic mice harboring mutant human UMOD gene.2008
- Author(s)
  Takiue Y, Hosoyamada M, Yokoo T, Kimura M, Ochiai M, Kaneko K, Ichida K, Hosoya T, Shibasaki T.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids. 27
  
  Pages: 596-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590547
[Journal Article] Production and characterization of transgenic mice harboring mutant human UMOD gene2008
- Author(s)
  Takiue Y, Hosoyamada M, Yokoo T, et al
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids 27
  
  Pages: 596-600
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590965
[Journal Article] Normal cadmium uptake in microcytic anemia mk/mk mice suggests that DMT1 is not the only cadmium transporter in vivo2008
- Author(s)
  Tomohito, Suzuki, Kanae, Momoi, Makoto, Hosoyamada, Masaki, Kimura, Toshiaki, Shibasaki
- Journal Title
  
  oxicology and Applied Pharmacology 227(3)
  
  Pages: 462-467
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590106
[Journal Article] Nephrin and Podocin Expression Around the Onset of Puromycin2005
- Author(s)
  Hosoyamada M, et al.
- Journal Title
  
  J Pharmacol Sci 97
  
  Pages: 234-241
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570771
[Journal Article] Neprhrin and podocin expression aroung the onset of puromycin aminonucleoside nephrosis.2005
- Author(s)
  Hosoyamada M, Yan K, Nishibori Y, Takiue Y, Kudo A, Kawkami H, Shibasaki T, Endou H
- Journal Title
  
  J.Pharmacol.Sci. 97
  
  Pages: 234-241
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Nephrin and Podocin Expression Around the Onset of Puromycin Aminonucleoside Nephrosis.2005
- Author(s)
  Hosoyamada M, et al.
- Journal Title
  
  J Pharmacol Sci 97
  
  Pages: 234-234
- NAID
  10025726124
- Data Source
  KAKENHI-PROJECT-14570771
[Journal Article] Mutations in human urate transporter 1 gene in presecretory reabsorption defect type of familial renal hypouricemia.2005
- Author(s)
  Wakida N, Tuyen do G, Adachi M, Miyoshi T, Nonoguchi H, Oka T, Ueda O, Tazawa M, Kurihara S, Yoneta Y, Shimada H, Oda T, Kikuchi Y, Matsuo H, Hosoyamada M, Endou H, Otagiri M, Tomita K, Kitamura K.
- Journal Title
  
  J Clin Endocrinol Metab. 90(4)
  
  Pages: 2169-2174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Neprhrin and podocin expression aroung the onset of puromycin aminonucleoside nephrosis.2005
- Author(s)
  Hosoyamada M, Yan K, Nishibori Y, Takiue Y, Kudo A, Kawkami H, Shibasaki T, Endou H
- Journal Title
  
  J.Pharmacol.Sci. 97
  
  Pages: 234-241
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Nephrin and Podocin Expression Around the Onset of Puromycin Aminonucleoside Nephrosis.2005
- Author(s)
  Hosoyamada M, Yan K, Nishibori Y, Takiue Y, Kudo A, Kawakami H, Shibasaki T, Endou H
- Journal Title
  
  J Pharmacol Sci 97
  
  Pages: 234-241
- NAID
  10025726124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570771
[Journal Article] Mutations in human urate transporter 1 gene in presecretory reabsorption defect type of familial renal hypouricemia.2005
- Author(s)
  Wakida N, Tuyen do G, Adachi M, Miyoshi T, Nonoguchi H, Oka T, Ueda O, Tazawa M, Kurihara S, Yoneta Y, Shimada H, Oda T, Kikuchi Y, Matsuo H, Hosoyamada M, Endou H, Otagiri M, Tomita K, Kitamura K.
- Journal Title
  
  J Clin Endocrinol Metab. 90(4)
  
  Pages: 2169-2174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion.2004
- Author(s)
  Ichida K, Hosoyamada M, Hisatome I, Enomoto A, Hikita M, Endou H, Hosoya T
- Journal Title
  
  J Am Soc Neprol 15
  
  Pages: 164-173
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese.2004
- Author(s)
  Iwai N, Mino Y, Hosoyamada M, Tago N, Kokubo Y, Endou H.
- Journal Title
  
  Kidney Int. 66
  
  Pages: 935-944
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese.2004
- Author(s)
  Iwai N, Mino Y, Hosoyamada M, Tago N, Kokubo Y, Endou H.
- Journal Title
  
  Kidney Int. 66
  
  Pages: 935-944
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane.2004
- Author(s)
  Nishibori Y, Liu L, Hosoyamada M, Endou H, Kudo A, Takenaka H, Higashihara E, Bessho F, Takahashi S, Kershaw D, Ruotsalainen V, Tryggvason K, Khoshnoodi J, Yan K
- Journal Title
  
  Kidney Int. 66
  
  Pages: 1755-1765
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion.2004
- Author(s)
  Ichida K, Hosoyamada M, Hisatome I, Enomoto A, Hikita M, Endou H, Hosoya T
- Journal Title
  
  J Am Soc Neprol 15
  
  Pages: 164-173
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] 尿酸トランスポーターの分子実体2004
- Author(s)
  細山田真, 金井好克, 遠藤仁
- Journal Title
  
  Gout and Nucleic Acid Metabolism 28(1)
  
  Pages: 1-5
- NAID
  10014068515
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Function and localization of urate transporter 1 in mouse kidney.2004
- Author(s)
  Hosoyamada M et al.
- Journal Title
  
  J Am Soc Nephrol 15・2
  
  Pages: 261-268
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571041
[Journal Article] Function and localization of urate transporter 1 in mouse kidney.2004
- Author(s)
  Hosoyamada M, Ichida K, Enomoto A, Hosoya T, Endou H.
- Journal Title
  
  J Am Soc Nephrol. 15(2)
  
  Pages: 261-268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Function and localization of urate transporter 1 in mouse kidney2004
- Author(s)
  Hosoyamada M
- Journal Title
  
  J Am Soc Nephrol 15(2)
  
  Pages: 261-268
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] 尿酸トランスポーターの分子実体2004
- Author(s)
  細山田真, 金井好克, 遠藤仁
- Journal Title
  
  Gout and Nucleic Acid Metabolism 28(1)
  
  Pages: 1-5
- NAID
  10014068515
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Function and localization of urate transporter 1 in mouse kidney2004
- Author(s)
  Hosoyamada M
- Journal Title
  
  J Am Soc Hephrol 15(2)
  
  Pages: 261-268
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Function and localization of urate transporter 1 in mouse kidney.2004
- Author(s)
  Hosoyamada M et al.
- Journal Title
  
  J Am Soc Nephrol 15-2
  
  Pages: 261-268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571041
[Journal Article] Function and localization of urate transporter 1 in mouse kidney.2004
- Author(s)
  Hosoyamada M, Ichida K, Enomoto A, Hosoya T, Endou H.
- Journal Title
  
  J Am Soc Nephrol. 15(2)
  
  Pages: 261-268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane.2004
- Author(s)
  Nishibori Y, Liu L, Hosoyamada M, Endou H, Kudo A, Takenaka H, Higashihara E, Bessho F, Takahashi S, Kershaw D, Ruotsalainen V, Tryggvason K, Khoshnoodi J, Yan K
- Journal Title
  
  Kidney Int 66
  
  Pages: 1755-1765
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570771
[Journal Article] Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane.2004
- Author(s)
  Nishibori Y, Liu L, Hosoyamada M, Endou H, Kudo A, Takenaka H, Higashihara E, Bessho F, Takahashi S, Kershaw D, Ruotsalainen V, Tryggvason K, Khoshnodi J, Yan K
- Journal Title
  
  Kidney Int. 66
  
  Pages: 1755-1765
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule.2003
- Author(s)
  Jutabha P, Kanai Y, Hosoyamada M, Chairoungdua A, Kim do K, Iribe Y, Babu E, Kim JY, Anzai N, Chatsudthipong V, Endou H.
- Journal Title
  
  J Biol Chem. 278(30)
  
  Pages: 27930-27938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule.2003
- Author(s)
  Jutabha P, Kanai Y, Hosoyamada M, Chairoungdua A, Kim do K, Iribe Y, Babu E, Kim JY, Anzai N, Chatsudthipong V, Endou H.
- Journal Title
  
  J Biol Chem. 278(30)
  
  Pages: 27930-27938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Urate transport via human PAH transporter hOAT1 and its gene structure.2003
- Author(s)
  Ichida K, Hosoyamada M, Kimura H, Takeda M, Utsunomiya Y, Hosoya T, Endou H.
- Journal Title
  
  Kidney Int. 63(1)
  
  Pages: 143-155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Urate transport via human PAH transporter hOAT1 and its gene structure.2003
- Author(s)
  Ichida K, Hosoyamada M, Kimura H, Takeda M, Utsunomiya Y, Hosoya T, Endou H.
- Journal Title
  
  Kidney Int. 63(1)
  
  Pages: 143-155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Molecular identification of a renal urate-anion exchanger that regulates blood urate levels.2002
- Author(s)
  Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Cha SH, Hosoyamada M, Takeda M, Sekine T, Igarashi T, Matsuo H, Kikuchi Y, Oda T, Ichida K, Hosoya T, Shimokata K, Niwa T, Kanai Y, Endou H.
- Journal Title
  
  Nature 417
  
  Pages: 447-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Molecular identification of a renal urate-anion exchanger that regulates blood urate levels.2002
- Author(s)
  Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Cha SH, Hosoyamada M, Takeda M, Sekine T, Igarashi T, Matsuo H, Kikuchi Y, Oda T, Ichida K, Hosoya T, Shimokata K, Niwa T, Kanai Y, Endou H.
- Journal Title
  
  Nature 417
  
  Pages: 447-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Characterizaion of organic anion transport inhibitors using cells stably expressing human organic anion tansporters.2001
- Author(s)
  Takeda M, Narikawa S, Hosoyamada M, Cha SH, Sekine T, Endou H.
- Journal Title
  
  Eur J Pharmacol. 419
  
  Pages: 113-120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Patent] ヒト尿酸代謝モデル動物2019
- Inventor(s)
  細山田　真
- Industrial Property Rights Holder
  帝京大学
- Industrial Property Rights Type
  特許
- Patent Publication Number
  2019-033708
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K08605
[Patent] ヒト尿酸代謝モデルマウス2017
- Inventor(s)
  細山田真
- Industrial Property Rights Holder
  細山田真
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-157930
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K08605
[Patent] ヒト尿酸代謝モデル動物2017
- Inventor(s)
  細山田真
- Industrial Property Rights Holder
  細山田真
- Industrial Property Rights Type
  特許
- Patent Publication Number
  2019-033708
- Filing Date
  2017
- Acquisition Date
  2019
- Data Source
  KAKENHI-PROJECT-17K08605
[Presentation] Na+依存性腎ヒポキサンチントランスポーター同定の試み2021
- Author(s)
  細山田真、渡部多真紀、富岡直子、安野伸浩）、柴田茂、内田俊也
- Organizer
  第54回日本痛風・尿酸核酸学会総会
- Data Source
  KAKENHI-PROJECT-18K08222
[Presentation] 新規高尿酸血症モデル HPRT高活性Uox-KOマウスに対するプリン型およ及び非プリン型XOR阻害薬の尿酸代謝に与える影響2019
- Author(s)
  細谷拓司、内田俊也，柴田茂、富岡直子、細山田真
- Organizer
  第52回日本痛風核酸代謝学会
- Data Source
  KAKENHI-PROJECT-17K08605
[Presentation] HPRT高活性XDHノックアウトマウスの寿命延長2019
- Author(s)
  細山田真、渡部多真紀、富岡直子、渡辺茂和、大坪俊夫、市田公美
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K08605
[Presentation] HPRT高活性XDHノックアウトマウスの寿命延長2019
- Author(s)
  細山田真、渡部多真紀、富岡直子、渡辺茂和、大坪俊夫、市田公美
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K08222
[Presentation] Establishment of high hypoxanthine phosphoribosyltransferase activity-uricase knockout mice as novel hyperuricemic model and effects of purine/nonpurine type xanthine oxidoreductase inhibitors2019
- Author(s)
  Takuji Hosoya, Syunya Uchida, Shigeru Shibata, Naoko H. Tomioka, Makoto Hosoyamada
- Organizer
  18th Symposium on Purine and Pyrimidine Metabolism in Man (PP19)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08605
[Presentation] 新規高尿酸血症モデルHPRT高活性Uox-KOマウスに対するプリン型及び非プリン型キサンチン酸化還元酵素阻害薬の効果2019
- Author(s)
  細谷拓司、富岡直子、細山田真
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08605
[Presentation] Life span extension of xanthine oxidoreductase knockout mouse by increase of HPRT activity2018
- Author(s)
  Makoto Hosoyamada, Naoko H Tomioka, Tomoko Fukuuchi, Toshio Ohtsubo, Kiyoko Kaneko, Kimiyoshi Ichida
- Organizer
  18th World Congress of basic and clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08605
[Presentation] ヒポキサンチンホスホリボシルトランスフェラーゼ(Hprt)高活性キサンチンデヒドロゲナーゼ(Xdh)ノックアウトマウスの作出2018
- Author(s)
  細山田真、富岡直子、大坪俊夫、市田公美、内田俊也、鎌谷直之
- Organizer
  第51回日本痛風核酸代謝学会総会
- Data Source
  KAKENHI-PROJECT-17K08605
[Presentation] Hprt高活性Xorノックアウトマウスの寿命延長メカニズムの検討2018
- Author(s)
  細山田真、福内友子、富岡直子、市田公美、金子希代子、大坪俊夫
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08605
[Presentation] キサンチンデヒドロゲナーゼノックアウトマウスが短命である理由の検討2018
- Author(s)
  安藤太介, 細山田真, 福内友子, 藤田恭子, 富岡直子, 金子希代子, 細山田真, 市田公美
- Organizer
  日本薬学会138年会
- Data Source
  KAKENHI-PROJECT-17K08605
[Presentation] HPRT高活性Xorノックアウトマウスの寿命延長メカニズムの検討2018
- Author(s)
  細山田真、福内友子、富岡直子、市田公美、金子希代子、大坪俊夫
- Organizer
  第61回日本腎臓学会学術大会
- Data Source
  KAKENHI-PROJECT-18K08222
[Presentation] HPRT高活性マウスを用いた血漿尿酸値のin vitro上昇メカニズムに関する検討2017
- Author(s)
  渡部多真紀、富岡直子、土屋雅勇、細山田　真
- Organizer
  第50回日本痛風・核酸代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2017-02-16
- Data Source
  KAKENHI-PROJECT-26460105
[Presentation] HPRT高活性マウスを用いた血漿尿酸値のin vitro上昇に関する検討2017
- Author(s)
  渡部多真紀，富岡直子，土屋雅勇，細山田真
- Organizer
  第50回日本痛風・核酸代謝学会
- Place of Presentation
  東京新宿
- Year and Date
  2017-02-17
- Data Source
  KAKENHI-PROJECT-26460347
[Presentation] 腎性低尿酸血症1型疾患モデル動物としてのUrat1-Uox-double KOマウスの検討2015
- Author(s)
  細山田　真、鶴見　ゆう、富岡　直子、関根　祐子、内田　俊也
- Organizer
  第48回日本痛風・核酸代謝学会総会
- Place of Presentation
  東京新宿
- Year and Date
  2015-02-20
- Data Source
  KAKENHI-PROJECT-26460347
[Presentation] 腎性低尿酸血症と運動後急性腎不全の疾患モデル動物としてのUrat1-Uox-ダブルノックアウトマウス2015
- Author(s)
  鶴見　ゆう、富岡　直子、関根　祐子、細山田　真
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18
- Data Source
  KAKENHI-PROJECT-26460347
[Presentation] 11.Urat1-Uox double knockout mice are experimental animal model of renal hypouricemia and exercise-induced acute kidney injury.2015
- Author(s)
  Hosoyamada M, Tsurumi Y, Tomioka NH, Sekine Y, Morisaki T, Uchida S
- Organizer
  16th International Symposium on Purine and Pyrimidine Metabolism in Man
- Place of Presentation
  New York, USA
- Year and Date
  2015-06-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460347
[Presentation] マウス脳内URAT1は脳室上衣細胞脳室側膜に局在する2014
- Author(s)
  富岡直子、中村真希子、市田公美、森崎隆幸、内田俊也、細山田真
- Organizer
  第47回日本痛風核酸代謝学会
- Place of Presentation
  神戸
- Year and Date
  2014-02-21
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] マウスにおける採血前および採血後偽高尿酸血症2014
- Author(s)
  渡部多真紀,富岡直子,渡辺茂和,土屋雅勇,細山田真
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] Urate transporter 1 (URAT1)は脳室上衣細胞に発現する2014
- Author(s)
  富岡直子、中村真希子、出口芳春、市田公美、森崎隆幸、細山田真
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Year and Date
  2014-03-21
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] 尿酸トランスポーターURAT1遺伝子およびウリカーゼ遺伝子ダブルノックアウトマウスの尿酸動態2014
- Author(s)
  細山田　真、鶴見　ゆう、富岡　直子、関根　祐子、内田　俊也
- Organizer
  第44回日本腎臓学会東部学術大会
- Place of Presentation
  東京新宿
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-26460347
[Presentation] ABCG2遺伝子の機能低下型変異は若年発症痛風の主要な病因である2013
- Author(s)
  中山昌喜,松尾洋孝,市田公美,髙田龍平,高田雄三,井上寛規,清水聖子,崎山真幸,細山田真,横尾隆,細谷龍男,清水徹,四ノ宮成祥
- Organizer
  第47回日本痛風・核酸代謝学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23591205
[Presentation] ヘパリン加マウス血液のα受容体刺激による尿酸生成2013
- Author(s)
  細山田真、渡部多真紀、富岡直子、道志勝、土屋雅勇
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] マウスの採血前および採血後偽高尿酸血症2013
- Author(s)
  渡部多真紀,富岡(原)直子,道志勝,渡辺茂和,細山田真,土屋雅勇
- Organizer
  第57回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2013-10-26
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] マウス血清尿酸値のインビトロ上昇2013
- Author(s)
  渡部多真紀、富岡直子、中村真希子、道志勝、金子希代子、内田俊也、藤森新、市田公美、土屋雅勇、細山田真
- Organizer
  第46回　日本痛風・核酸代謝学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] ヘパリン加マウス血液のα受容体刺激による尿酸生成2013
- Author(s)
  細山田真、渡部多真紀、富岡直子、道志勝、土屋雅勇
- Organizer
  第86回　日本薬理学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] FALSE INCREASE OF URIC ACID LEVEL OF MOUSE BLOOD IN VITRO2013
- Author(s)
  Hosoyamada-M, Watanabe-T, Tomioka-NH, Doshi-M, Watanabe-S, Tsuchiya-M
- Organizer
  15th International Symposium on Purine and Pyrimidine Metabolism in Man
- Place of Presentation
  Madrid, Spain
- Year and Date
  2013-06-10
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] 家族性若年性高尿酸血症性腎症1型モデルマウス腎臓では5'-レダクターゼ2発現が増加する2013
- Author(s)
  細山田真、富岡直子、道志勝
- Organizer
  第56回日本腎臓学会総会
- Place of Presentation
  東京
- Year and Date
  2013-05-11
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] 腸管尿酸排泄低下に起因する新たな「腎負荷型」高尿酸血症の解明2013
- Author(s)
  中村　真希子, 松尾　洋孝,高田　龍平, 中山　昌喜, 清水　徹, 細山田　真, 四ノ宮　成祥, 鈴木　洋史, 細谷　龍男, 市田　公美
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591205
[Presentation] マウス血清尿酸値のインビトロ上昇2013
- Author(s)
  渡部多真紀、富岡直子、中村真希子、道志勝、金子希代子、内田俊也、藤森新、市田公美、土屋雅勇、細山田真
- Organizer
  第46回日本痛風・核酸代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2013-02-14
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] Novel common mechanism of hyperuricemia by decreased extra-renal urate excretion2012
- Author(s)
  Ichida K, Matsuo H, Takada T, Nakayama A, Murakami K, Shimizu T, Yamanashi Y, Kasuga H, Nakashima H, Nakamura T, Takada Y, Kawamura Y, Utsumi Y, Nakamura M, Hosoyamada M, Sakurai Y, Shinomiya N, Hosoya T, Suzuki H
- Organizer
  European Human Genetics Conference 2012
- Place of Presentation
  Nürnberg, Germany
- Data Source
  KAKENHI-PROJECT-23591205
[Presentation] ウリカーゼノックアウトマウスにおけるアロプリノール投与の影響2012
- Author(s)
  細山田真、金子希代子、内田俊也、藤森新
- Organizer
  第45回日本痛風・核酸代謝学会総会
- Place of Presentation
  奈良
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] Fluoresceinを用いた尿酸トランスポーター機能評価法の開発2012
- Author(s)
  中村真希子、荒川伸介、松尾広大、細山田真、安西尚彦、市田公美
- Organizer
  第45回日本痛風・核酸代謝学会総会
- Place of Presentation
  奈良
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] The effect of sex hormones upon urate transport systems in the mouse kidney.2011
- Author(s)
  Takiue Y, Hosoyamada M, Kimura M, Saito H
- Organizer
  14th International Symposium on Purine and Pyrimidine Metabolism in Man
- Place of Presentation
  PP11 Tokyo
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] ウロモジュリンと家族性若年性高尿酸血症性腎症1型2011
- Author(s)
  細山田真,滝上裕一,齋藤英胤
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] 家族性若年性高尿酸血症性腎症1型モデルマウス腎臓では5'-レダクターゼ2発現が増加する2011
- Author(s)
  細山田真,岩川奈々,滝上裕一,木村真規,齋藤英胤
- Organizer
  第84回日本薬理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] 抗human URAT1抗体の新規作出2011
- Author(s)
  細山田真
- Organizer
  第44回日本痛風・核酸代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2011-02-17
- Data Source
  KAKENHI-PROJECT-20590965
[Presentation] ウロモジュリンの遺伝子変異によるアンドロゲン作用の増加2011
- Author(s)
  滝上裕一,細山田真,木村真規,齋藤英胤
- Organizer
  第44回日本痛風・核酸代謝学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] シンポジウム2「トランスポーター研究の最前線」腎臓における尿酸輸送2010
- Author(s)
  細山田真
- Organizer
  第54回日本薬学会関東支部大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] 性ホルモンによる尿酸動態の変化2010
- Author(s)
  滝上裕一,細山田真,木村真規,柴崎敏昭
- Organizer
  第43回日本痛風・核酸代謝学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] 尿酸再吸収トランスポーターの性ホルモンによる発現調節2010
- Author(s)
  滝上裕一,細山田真,木村真規,柴崎敏昭
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] Establishment and analysis of Slc22a12(Urat1)knockout mouse2009
- Author(s)
  Hosoyamada M
- Organizer
  13th International Symposium on Purine and Pyrimidine Metabolism in Man
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] 家族性若年性高尿酸血症性腎症モデルマウスの腎臓における内因性マウスウロモジュリンの蓄積2009
- Author(s)
  滝上裕一, 細山田真, 他
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] Development of LC-MS method for detection of the mutated uromodulin.2009
- Author(s)
  Yasuda M, Kaneko K, Hachisu H, Ochiai M, Yamanobe T, Mawatari K, Nakagomi K, Minoura N, Hosoyamada M
- Organizer
  13th International Symposium on Purine and Pyrimidine Metabolism in Man
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] LC-MSを用いた変異ウロモジュリン検出法の開発2009
- Author(s)
  安田誠,蜂須広佳,落合真奈美,金子希代子,山辺智代,馬渡健一,中込和哉,箕浦憲彦,細山田真
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] シンポジウム2「低尿酸血症の臨床的意義」低尿酸血症の分子メカニズム(Urat1ノックアウトマウスの作出と検討)2009
- Author(s)
  細山田真
- Organizer
  第42回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] 家族性若年性高尿酸血症性腎症モデルマウスの腎臓における内因性マウスウロモジュリンの蓄積2009
- Author(s)
  滝上裕一,木村真規,細山田真,柴崎敏昭
- Organizer
  第82回日本薬理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] Single nucleotide polymorphisms in ABCG2 in Japanese hyperuricemic patients.2009
- Author(s)
  Ichida K, Matsuo H, Hosoyamada M, Shinomiya N, Hosoya T
- Organizer
  13th International Symposium on Purine and Pyrimidine Metabolism in Man
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] Establishment and analysis of Slc22a12 (Urat1) knockout mouse.2009
- Author(s)
  Hosoyamada M, Morisaki H, Cheng J, Ikawa M, Okabe M, Morisaki T, Takiue Y, Ichida K, Hosoya T, Shibasaki T
- Organizer
  13th International Symposium on Purine and Pyrimidine Metabolism in Man
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] マウス尿酸トランスポーターmURAT1の性ホルモンによる発現調節機構2009
- Author(s)
  滝上裕一,細山田真,木村真規,柴崎敏昭
- Organizer
  第42回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] LC-MSを用いた変異ウロモジュリン検出法の開発2009
- Author(s)
  安田誠,蜂須広佳,落合真奈美,金子希代子,山辺智代,藤森新,馬渡健一,中込和哉,箕浦憲彦,細山田真
- Organizer
  第42回日本痛風・核酸代謝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] ウロモジュリン蛋白の蓄積は遺伝子変異が原因である2009
- Author(s)
  滝上裕一,中込早苗,木村真規,細山田真,柴崎敏昭
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590547
[Presentation] DMT1 and cadmium transport under iron depletion2007
- Author(s)
  Tomohito, Suzuki, Yoshiki, Ishikubo, Masaki, Kimura, Makoto, Hosoyamada, Toshiaki, Shibasaki
- Organizer
  Forum 2007 hygiene pharmacology environmental toxicology
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590106
[Presentation] 鉄欠乏時のDMT1とカドミウム輸送2007
- Author(s)
  鈴木友人, 石久保義紀, 木村真規, 細山田真, 柴崎敏昭
- Organizer
  フォーラム2007衛生薬学、環境トキシコロジー
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590106
[Presentation] 家族性若年性高尿酸血症性腎症1型モデルマウス腎臓では5’-レダクターゼ2発現が増加する
- Author(s)
  細山田真、富岡直子、道志勝
- Organizer
  第56回日本腎臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] Urate transporter 1 (URAT1) は脳室上衣細胞に発現する
- Author(s)
  富岡直子、中村真希子、出口芳春、市田公美、森崎隆幸、細山田真
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] ウリカーゼノックアウトマウスにおけるアロプリノール投与の影響
- Author(s)
  細山田真、金子希代子、内田俊也、藤森新
- Organizer
  第45回日本痛風・核酸代謝学会総会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] マクロファージ遊走阻止因子（ＭＩＦ）はdb/dbマウスにおける微量アルブミン尿惹起因子である可能性がある
- Author(s)
  細山田真, 渡部多真紀,富岡直子, 渡辺茂和, 土屋雅勇
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-26460105
[Presentation] マウス脳内URAT1は脳室上衣細胞脳室側膜に局在する
- Author(s)
  富岡直子、中村真希子、市田公美、森崎隆幸、内田俊也、細山田真
- Organizer
  第47回日本痛風核酸代謝学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] マウスの採血前および採血後偽高尿酸血症
- Author(s)
  渡部多真紀，富岡（原）直子，道志勝，渡辺茂和，細山田真，土屋雅勇
- Organizer
  第57回日本薬学会関東支部大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591340
[Presentation] マウスにおける採血前および採血後偽高尿酸血症
- Author(s)
  渡部多真紀，富岡直子，渡辺茂和，土屋雅勇，細山田真
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23591340

1. ENDOU Hitoshi (20101115)

# of Collaborated Projects: 13 results

# of Collaborated Products: 21 results
2. KANAI Yoshikatdu (60204533)

# of Collaborated Projects: 11 results

# of Collaborated Products: 8 results
3. SEKINE Takashi (50255402)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
4. TAKEDA Michio (40255401)

# of Collaborated Projects: 10 results

# of Collaborated Products: 3 results
5. ICHIDA Kimiyoshi (80183169)

# of Collaborated Projects: 9 results

# of Collaborated Products: 25 results
6. CHA Seok ho (50276200)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
7. INATOMI Jun (00311960)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
8. ANZAI Naohiko (70276054)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
9. KIM Do Kyung (40327474)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
10. NAKAMURA Makiko (80447557)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
11. HIRATA Taku (60372918)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. HOSOYA Tatsuo (10125031)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
13. MATSUO Hirotaka (00528292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
14. WATANABE Tamaki (40453691)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
15. TATE Naoko (00201955)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. IRIBE Yuji (20348618)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
17. 富岡直子 (60525814)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
18. 金子希代子 (90147075)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
19. SHINOHARA Yoshihiko (00154229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. JUTABHA Promsuk (90541748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. KIMURA Toru (30433725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NAKAMURA Yoshihiro (60415255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
23. YAN Kunimasa (70255389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. KUDO Akihiko (80255398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
25. TOSHIAKI Shibasaki (60100921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
26. KIMURA Masaki (40383666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
27. UENO Takeshi (20406979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KIMIURA Toru (60383668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. MORISAKI Takayuki (30174410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. DEGUCHI YOSHIHARU (40254255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. OKURA TAKASHI (80326123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. HIGUCHI KEI (10625304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 長谷川誠 (70014107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 土屋雅勇 (80398586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
35. 関根祐子 (30567350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
36. TROTTI David

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. HEDIGER Matt

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 横山宏和

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. CHAIROUNGDUA A

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. NAGAMORI Shushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. SHINOMIYA Nariyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 高田龍平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
43. 山本健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 浜嶋信之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 白吉安昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 李佩俐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 鈴木洋史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 内田俊也

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
49. 柴田茂

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Hosoyamada Makoto 細山田 真

HOSOYAMADA Makoto 細山田 真

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Elucidation of the mechanism of exercise-induced acute kidney injury associated with renal hypouricemia type 1 model micePrincipal Investigator

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Generation of human urate metabolism complete model mice by suppressing xanthine dehydrogenase expressionPrincipal Investigator

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Elucidation of environmental factors involved in the onset of hyperuricemia using complete model animals of human uric acid metabolismPrincipal Investigator

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Elucidation of the pathogenic mechanism of hyperuricemia in obesity and metabolic syndromePrincipal Investigator

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Production of disease model mice for the drug screening of familial juvenile hyperuricemic nephropathyPrincipal Investigator

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Analysis of the onset mechanism of acute renal failure post exercise using urate transporter knockout micePrincipal Investigator

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Hosoyamada Makoto 細山田真

HOSOYAMADA Makoto 細山田真