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Yan Kunimasa  楊 國昌

ORCIDConnect your ORCID iD *help
… Alternative Names

楊 國昌  ヤン クニマサ

YAN KUNIMASA  楊 國昌

YAN Kunimasa  楊 國昌

楊国 昌  ヤンクニ マサ

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Researcher Number 70255389
Other IDs
External Links
Affiliation (Current) 2022: 杏林大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help 2019 – 2020: 杏林大学, 医学部, 教授
2015 – 2017: 杏林大学, 医学部, 教授
2009 – 2012: Kyorin University, 医学部, 教授
2007: Kyorin University, Faculty of Medicine, Associate Professor
2006: 杏林大学, 医学部, 助教授
2002 – 2004: 杏林大学, 医学部, 助教授
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Pediatrics / Pediatrics / Basic Section 53040:Nephrology-related
Except Principal Investigator
General pharmacology / Pediatrics / Pediatrics
Keywords
Principal Investigator
ネフローゼ / mTOR / ポドサイト / zebrafish / 糖質ステロイド / T細胞 / アポトーシス / Glcci1 / Dlc8 / PAK1 … More / T細胞 / 胸腺 / 細胞内骨格 / ステロイド / 精巣 / 糸球体 / ポドシン / ネフリン / スリット膜 / 蛋白輸送 / ミスセンス変異 / 蛋白細胞内輸送 / Podocin / Nephrin / 細胞内蛋白輸送 / podocin / nephrin / slit membrane / protein transport / missense mutant / アミノ酸輸送体 / 半月体形成性腎炎 / アミノ酸 / 輸送体 / amino acid transporter / podocyte / crescentic glomerulonephritis / 糸球体硬化 / 質量解析 / アドリアマイシン / NEP25 / メタボローム / プロテオーム / 創薬 … More
Except Principal Investigator
LAT1 / BCH / トランスポーター / 尿酸 / 痛風 / 高尿酸血症 / 腎尿細管 / 薬理学 / 遺伝子 / 蛋白質 / 小児腎 / 泌尿器学 / ユビキチン / ネフローゼ / インヒビター / 骨髄細胞 / 急性リンパ球性白血病 / 急性骨髄性白血病 / 白血病細胞株 / 造血幹細胞 / 小児白血病 / 4F2hc / アミノ酸トランスポーター / MTTアッセイ / LD50 / 凍結切片 / ウェスタンブロット / 細胞内局在 / ゼラチンカプセル / 抗原特異性 / 抗LAT1モノクローナル抗体 / 倫理委員会 / インフォームドコンセント / inhibitor / bone marrow cells / acute lymphocytic leukemia / acute myeloid leukemia / cell lines / hematopoietic stem cells Less
  • Research Projects

    (8 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (27 People)
  •  創薬のための統合オミックス解析による難治性ネフローゼの病因・病態探索Principal Investigator

    • Principal Investigator
      楊 國昌
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Kyorin University
  •  Integration of proteomics and metabolomics for drug discovery based on a search for the pathophysiology in glomerulosclerosisPrincipal Investigator

    • Principal Investigator
      YAN KUNIMASA
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Kyorin University
  •  Role of Ubiquitin specific protease 40 in Glomerulus

    • Principal Investigator
      NISHIBORI Yukino
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyorin University
  •  New drug development for hyperuricemia targeting novel urate efflux transporter URATv1

    • Principal Investigator
      ANZAI Naohiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Dokkyo Medical University
      Kyorin University
  •  Functional analysis of glucocorticoid induced transcript 1(GLCCI1)Principal Investigator

    • Principal Investigator
      YAN Kunimasa
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyorin University
  •  Role of System LAmino Acid Transporter in Podocyte Cell BiologyPrincipal Investigator

    • Principal Investigator
      YAN Kunimasa
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Kyorin University
  •  Protein analysis of steroid resistant congenital nephrotic syndrome gene: podocinPrincipal Investigator

    • Principal Investigator
      YAN Kunimasa
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyorin University
  •  Analysis of Expression of LAT1 in Childhood Leukemia and Effect of Inhibitors on Proliferation Inhibition

    • Principal Investigator
      BESSHO Fumio
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kyorin University

All 2015 2012 2010 2007 2005 2004 2003

All Journal Article Presentation

  • [Journal Article] Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate2010

    • Author(s)
      Jutabha P, Anzai N, Kitamura K, Taniguchi A, Kaneko S, Yan K, Yamada H, Shimada H, Kimura T, Katada T, Fukutomi T, Tomita K, Urano W, Yamanaka H, Seki G, Fujita T, Moriyama Y, Yamada A, Uchida S, Wempe MF, Endou H, Sakurai H
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 35123-35132

    • DOI

      10.1074/jbc.m110.121301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390073
  • [Journal Article] Protein Characterization of Na+-Independent System L Amino Acid Transporter 3 in Mice : A Potential Role in Supply of Branched-Chain Amino Acids under Nutrient Starvation2007

    • Author(s)
      Fukuhara, D., Kanai, Y., Chairoungdua, A., Babu, E., Bessho, F., Kawano, T., Akimoto, Y., Endou, H., Yan, K
    • Journal Title

      Am J Pathol 170(3)

      Pages: 888-98

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590901
  • [Journal Article] Nephrin and Podocin Expression Around the Onset of Puromycin Aminonucleoside Nephrosis.2005

    • Author(s)
      Hosoyamada M, Yan K, Nishibori Y, Takiue Y, Kudo A, Kawakami H, Shibasaki T, Endou H
    • Journal Title

      J Pharmacol Sci 97

      Pages: 234-241

    • NAID

      10025726124

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570771
  • [Journal Article] Characterization of the interactions of the nephrin intracellular domain.2005

    • Author(s)
      Liu XL, Kilpelainen P, Hellman U, Sun Y, Wartiovaara J, Morgunova E, Pikkarainen T, Yan K, Jonsson AP, Tryggvason K
    • Journal Title

      FEBS J 272

      Pages: 228-243

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570771
  • [Journal Article] ネフリンの糖鎖異常2004

    • Author(s)
      楊 國昌, 他
    • Journal Title

      Annual Review腎臓 1

      Pages: 27-32

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570771
  • [Journal Article] Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane.2004

    • Author(s)
      Nishibori Y, Liu L, Hosoyamada M, Endou H, Kudo A, Takenaka H, Higashihara E, Bessho F, Takahashi S, Kershaw D, Ruotsalainen V, Tryggvason K, Khoshnoodi J, Yan K
    • Journal Title

      Kidney Int 66

      Pages: 1755-1765

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570771
  • [Journal Article] Defective trafficking of nephrin missense mutants rescued by a chemical chaperone.2004

    • Author(s)
      Liu XL, Done SC, Yan K, Kilpelainen P, Pikkarainen T, Tryggvason K
    • Journal Title

      J Am Soc Nephrol 15

      Pages: 1731-1738

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570771
  • [Journal Article] Variable expression of podocyte-related markers in the glomeruloid bodies in Wilms tumor.2003

    • Author(s)
      Kanemoto K, Takahashi S, Shu Y, Usui J, Tomari S, Yan K, Hamazaki Y, Nagata M
    • Journal Title

      Pathol Int 53

      Pages: 596-601

    • NAID

      10012439208

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570771
  • [Journal Article] 後天性腎疾患におけるネフリンの役割2003

    • Author(s)
      楊 國昌
    • Journal Title

      腎と透析 55

      Pages: 771-776

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570771
  • [Presentation] プロテオーム解析による糸球体硬化の病態解明2015

    • Author(s)
      西堀由紀野,高橋昌兵,福冨俊之,秋元義弘,楊國昌
    • Organizer
      第50回日本小児腎臓病学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2015-06-18
    • Data Source
      KAKENHI-PROJECT-15K09270
  • [Presentation] (Department o Pediatrics,Anatomy, Pharmacology,Lab Membrane Biochemistry and Biophysics Graduate School of Biostudies, Kyoto University)Role of ubiquitin specific protease 40(USP40) in glomerular development.2012

    • Author(s)
      Takagi H, Nishibori Y, Kiuchi Z, Ito Y, Kudo A, Akimoto Y, Kimura T, Takematsu H, Yan K
    • Organizer
      The 4thEMBO meeting 2012
    • Place of Presentation
      Nice
    • Data Source
      KAKENHI-PROJECT-22591191
  • [Presentation] (杏林大・医・小児科・ 薬理学・ 解剖):糸球体の発生に置けるユビキチン特異的プロテアーゼ40(USP40)の役割2012

    • Author(s)
      高木永, 西堀由紀野, 木村徹,宮東昭彦, 楊國昌
    • Organizer
      第47回日本小児腎臓病学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22591191
  • 1.  AKIMOTO Yoshihiro (60184115)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 2.  KANAI Yoshikatsu (60204533)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 3.  FUKUTOMI Toshiyuki (30439187)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 4.  ISHIGAKI Yasuhito (20232275)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  NISHIBORI Yukino (70407021)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 6.  ENDOU Hitoshi (20101115)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  ANZAI Naohiko (70276054)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  UCHIDA Kohsuke (30168695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  KOJIMA Shuichi (60178267)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  DOMAE Mariko (20285878)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HAYASHI Keitaro (10323106)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KIMURA Toru (30433725)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  MIURA Daisaku (60510873)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KAWAHARA Katsumasa (70134525)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  BESSHO Fumio (40010285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YOSHINO Hiroshi (30333032)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HOSOYAMADA Makoto (00291659)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  KUDO Akihiko (80255398)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 19.  OKUNO YASUSHI (20283666)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MATSUSAKA TAIJI (50317749)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  清水 章 (00256942)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  田中 絵里子 (80439827)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  TSUKADA Ai
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  WEMPE Michael F.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 25.  AMMONPATUMRAT Sirirat
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  THAMMAPRATIP Thanapol
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  宮嶋 伸一郎
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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