Endou Hitoshi 遠藤仁

… Alternative Names

Researcher Number	20101115
External Links
Affiliation (Current)	2021: 杏林大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information) *help	2004: Kyorin University, Professors emeritus, 名誉教授 1993 – 2004: Department of Pharmacology and Toxicology, Kyorin University School of Medicine, 医学部, 教授 1991 – 1992: Department of Pharmacology, Faculty of Medicine, University of Tokyo, 医学部(医), 助教授 1990 – 1992: 東京大学, 医学部, 助教授 1991: Department of Pharmacology, Faculty of Medicine, University of Tokyo Associate P … More
Review Section/Research Field	Principal Investigator 応用薬理学・医療系薬学 / General pharmacology / Biological Sciences Except Principal Investigator Kidney internal medicine / General pharmacology / Otorhinolaryngology / 医学一般 / 応用薬理学・医療系薬学 / Cell biology / Pediatrics
Keywords	Principal Investigator 有機アニオントランスポーター / LAT1 / LAT2 / 必須アミノ酸 / 近位尿細管 / 有機アニオン / ジカルボン酸 / トランスポーター / ジカルボン酸トランスポーター / 中性アミノ酸トランスポーター … More Except Principal Investigator kidney / トランスポーター / LAT1 / organic anion transporter / pharmacokinetics / 尿細管 / 腎 / 膜輸送 / Transporter / Central nervous system / Caspase / Cell cycle / Cell line / purinoceptor / intracellular calcium / ATP / proximal tubules / hOAT1 / transporter / organic anion / 造血幹細胞 / 薬物輸送 / drug transporter / liver / brain / organic anion transporter1 / organic anion transporter2 / organic anion transporter3 / knockout mouse / 安定発現細胞 / 近位尿細管 / 有機アニオントランスポータ / Proximal tubule / BCH / 鼻粘膜 / LAT2 / OAT1 / OAT3 / OAT4 / 多選択性有機アニオントランスポーター / モノカルボン酸トランスポーター / human OAT1 / 自動調節機構 / 腎機能 / ホルモン / 体液 / メサンジウム細胞 / 情報伝達 / 水チャネル / エンドセリン / レセプター / バゾプレッシン / オ-トクリン / カルシウムイオン / 腎尿細管 / cAMP / 体液調節 / 内分泌 / 高血圧 / 利尿 / autoregulation / renal function / hormones / body fluid / mesangium cell / tubular cell / signal transduction / water channel / グルタミン酸 / 中枢神経系 / 神経伝達 / 神経毒性 / 興奮毒性 / Glutamate / neuro transmission / neurotoxicity / excitotoxicity / membrane transport / シスプラチン / アポトーシス / 腎由来細胞株 / c-fos / 活性酸素 / 細胞周期制御 / G_2 arrest / SV40 / ICE family protease / ICE / CPP32 / CrmA / Cisplatin / Apoptosis / Oncogene / Free radical / nephron segment / mesangial cell / purinoreceptor / protein kinase C / phosphorylation / nephron / calcium / P_<2Y> / P_<2U> / 細胞内カルシウム / desensitization / nephron segments / mesangial cells / アミノ酸 / 酸化的ストレス / システイン / シスチン / 中枢神経 / 分子薬理学 / 神経細胞 / クローニング / グリオーマ / Membrane transport / amino acids / oxidative stress / cystine / cysteine / Molewlar Pharmawlogy / 有機酸 / 培養細胞 / 腎臓 / culture cell / トランスジェニックマウス / 機能細胞 / 組織再構成 / T-抗原 / 多能性幹細胞 / トランスゲニックマウス / トランスゲニックラット / 生体組織再構築 / 細胞分化 / transgenic mouse / differentiated cells / tissue reconstruction / T-antigen / multipotent stem cells / 有機アニオン / 有機カチオン / 薬物動態 / 血液・組織関門 / 分子クローニング / placenta / cloning / organic cation / drug transport / blood-brain barrier / molecular cloning / gene targetting / gene targeting / 有機アニオントランスポーター / セファロリジン / セファロスポリン系抗生物質 / 薬物性腎障害 / Organic anion transporter / Cephaloridine / Nephrotoxicity / Ochratoxin A / インヒビター / 骨髄細胞 / 急性リンパ球性白血病 / 急性骨髄性白血病 / 白血病細胞株 / 小児白血病 / 4F2hc / アミノ酸トランスポーター / MTTアッセイ / LD50 / 凍結切片 / ウェスタンブロット / 細胞内局在 / ゼラチンカプセル / 抗原特異性 / 抗LAT1モノクローナル抗体 / 倫理委員会 / インフォームドコンセント / inhibitor / bone marrow cells / acute lymphocytic leukemia / acute myeloid leukemia / cell lines / hematopoietic stem cells / ヒト有機アニオントランスポータ / ヒト有機カチオントランスポータ / 尿細管分泌 / 臨床的意義 / ヒト有機カキオントランスポータ / 有機カチオントランスポータ / 腎排泄 / Human organic anion transporter / Human organic cation transporter / Drug transport / Tubular secretion / Clinical implication / stable cell line Less

リバースオンコロジー;がん胎児性LAT1抑制薬による遺伝子変化の網羅的解析Principal Investigator
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyorin University
がん特異中性アミノ酸トランスポーター(LAT1)の発現と制御機序Principal Investigator
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyorin University
Development of novel anti-uricosuric agents based on the genomic strategy.Principal Investigator
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
がん胎児性中性アミノ酸トランスポーター(LAT1)の発現と細胞のがん化機構と制御Principal Investigator
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyorin University
Genetic Abnormality of Renal Proximal Tubule-Specific Transporters as Causes of Sudden Death Syndrome in South-Eastern AsiaPrincipal Investigator
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
Analysis of Expression of LAT1 in Childhood Leukemia and Effect of Inhibitors on Proliferation Inhibition
- Principal Investigator
  
  BESSHO Fumio
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kyorin University
Clinical implication of organic anion transporters in the proximal tubule
- Principal Investigator
  
  TAKEDA Michio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
がん胎児性中性アミノ酸トランスポーター(LAT1)の発現と細胞のがん化機構と制御Principal Investigator
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyorin University
Identification of transporter genes regulating systemic kinetics of drugs and foreign compounds and their genetic polymorphismPrincipal Investigator
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
In vitro reconstruction of tissue function with the immortalized cell lines from transgenic mouse
- Principal Investigator
  
  OBINATA Masuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  TOHOKU UNIVERSITY
Cloning of transporters for anionic drugs and the application to pharmacokinetic analysis
- Principal Investigator
  
  KANAI Yoshikatsu, 関根孝司
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
FUNCTIONAL ANALYSIS OF THE ANIONIC DRUG TRANSPORTERS USING KNOCKOUT MICE
- Principal Investigator
  
  INATOMI Jun, 車碩鎬
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
The elucidation of cephaloridine-induced nephrotoxicity in cell lines stably expressing organic anion transporters
- Principal Investigator
  
  TAKEDA Michio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
Molecular mechanisms of drug transport across cell membranePrincipal Investigator
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
鼻粘膜薬物吸収におけるトランスポーターの役割に関する研究
- Principal Investigator
  
  長谷川誠
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kyorin University
Development of artificial kidney hybridized with human organic anion transporter expressed cells
- Principal Investigator
  
  HOSOYAMDA Makoto
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
東アジアに多発する尿路結石の実態と素因Principal Investigator
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
有機アニオン輸送の細胞内分子機序Principal Investigator
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyorin University
New roprorective roles of amino acid transporrers
- Principal Investigator
  
  KANAI Yoshikatdu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Molecular cloning and functional expression of kidney-specific organic anionic drug transportersPrincipal Investigator
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University School of Medicine
Elucidation of the intracellular mechanisms of cisplatin-induced apoptosis in renal cell line
- Principal Investigator
  
  TAKEDA Michio
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University School of Medicine
The study toward the development of specific agonist and antagonist for the purinergic receptors in the kidney
- Principal Investigator
  
  SEKINE Takashi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
腎毒性予測法の開発Principal Investigator
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
Role of vanadium in endemic diseases in Northeast ThailandPrincipal Investigator
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyorin University School of Medicine
Roles of glutamate transporters in the nervous system
- Principal Investigator
  
  KANAI Yoshikatsu
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyorin University
新しいvasopressin受容体(Vp)の構造と機能に関する分子薬理学的研究Principal Investigator
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
  The University of Tokyo
Endemic Primary Distal Renal Tubular Acidosis in ThailandPrincipal Investigator
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyorin University School of Medicine
  The University of Tokyo
Establishment of immotalized cell lines from transgenic mouse nephron segmentsPrincipal Investigator
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Department of Pharmacology and Toxicology, Kyorin University School of Medicine
  The University of Tokyo
Study on Autoregulatory Mechanism of Body Fluid with Special Emphasis on Kidney and Hormones
- Principal Investigator
  
  MARUMO Fumiaki
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  医学一般
- Research Institution
  Tokyo Medical and Dental University
Podocalyxinの構造と機能に関する薬理学的研究Principal Investigator
- Principal Investigator
  
  遠藤仁
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo
Establishment of screening systems for evaluating drug actions in the kidneyPrincipal Investigator
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Faculty of Medicine, University of Tokyo
ULTRAMICRO METHODS FOR DETERMINING ENZYME ACTIVITIES AND SUBSTRATES USING COMBINED BIOLUMINESCENT ASSAY WITH ENZYMATIC CYCLINGPrincipal Investigator
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  General pharmacology
- Research Institution
  UNIVERSITY OF TOKYO
Intrarenal actions of atrial natriuretic peptidesPrincipal Investigator
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  University of Tokyo

All 2006 2005 2004 2003 2002 2001 Other

All Journal Article Patent

[Journal Article] A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter.2006
- Author(s)
  Shigeta Y, Kanai Y, Chairoungdua A, Ahmed N, Sakamoto S, Matsuo H, Kim DK, Fujimura M, Anzai N, Mizoguchi K, Ueda T, Akakura K, Ichikawa T, Ito H, Endou H.
- Journal Title
  
  Kidney Int. 69(7)
  
  Pages: 1198-1206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Dual-color imaging of nuclear-cytoplasmic dynamics, viability, and proliferation of cancer cells in the portal vein area.2006
- Author(s)
  Tsuji K, Yamauchi K, Yang M, Jiang P, Bouvet M, Endo H, Kanai Y, Yamashita K, Moossa AR, Hoffman RM.
- Journal Title
  
  Cancer Res. 66(1)
  
  Pages: 303-306
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Molecular physiology of renal organic anion transporters.2006
- Author(s)
  Sekine T, Miyazaki H, Endou H.
- Journal Title
  
  Am J Physiol Renal Physiol. 290(2)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter.2006
- Author(s)
  Shigeta Y, Kanai Y, Chairoungdua A, Ahmed N, Sakamoto S, Matsuo H, Kim DK, Fujimura M, Anzai N, Mizoguchi K, Ueda T, Akakura K, Ichikawa T, Ito H, Endou H.
- Journal Title
  
  Kidney Int. 69(7)
  
  Pages: 1198-1206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Dual-color imaging of nuclear-cytoplasmic dynamics, viability, and proliferation of cancer cells in the portal vein area.2006
- Author(s)
  Tsuji K, Yamauchi K, Yang M, Jiang P, Bouvet M, Endo H, Kanai Y, Yamashita K, Moossa AR, Hoffman RM.
- Journal Title
  
  Cancer Res. 66(1)
  
  Pages: 303-306
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Molecular physiology of renal organic anion transporters.2006
- Author(s)
  Sekine T, Miyazaki H, Endou H.
- Journal Title
  
  Am J Physiol Renal Physiol. 290(2)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction.2005
- Author(s)
  Villar SR, Brandoni A, Anzai N, Endou H, Torres AM.
- Journal Title
  
  Kidney Int. 68(6)
  
  Pages: 2704-2713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Molecular physiology of urate transport.2005
- Author(s)
  Hediger MA, Johnson RJ, Miyazaki H, Endou H.
- Journal Title
  
  Physiology (Bethesda). 20
  
  Pages: 125-133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Neprhrin and podocin expression aroung the onset of puromycin aminonucleoside nephrosis.2005
- Author(s)
  Hosoyamada M, Yan K, Nishibori Y, Takiue Y, Kudo A, Kawkami H, Shibasaki T, Endou H
- Journal Title
  
  J.Pharmacol.Sci. 97
  
  Pages: 234-241
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins.2005
- Author(s)
  Miyazaki H, Anzai N, Ekaratanawong S, Sakata T, Shin HJ, Jutabha P, Hirata T, He X, Nonoguchi H, Tomita K, Kanai Y, Endou H.
- Journal Title
  
  J Am Soc Nephrol. 16(12)
  
  Pages: 3498-3506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Integrated physiology of proximal tubular organic anion transport.2005
- Author(s)
  Anzai N, Jutabha P, Kanai Y, Endou H.
- Journal Title
  
  Curr Opin Nephrol Hypertens. 14(5)
  
  Pages: 472-479
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins.2005
- Author(s)
  Miyazaki H, Anzai N, Ekaratanawong S, Sakata T, Shin HJ, Jutabha P, Hirata T, He X, Nonoguchi H, Tomita K, Kanai Y, Endou H.
- Journal Title
  
  J Am Soc Nephrol. 16(12)
  
  Pages: 3498-3506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Integrated physiology of proximal tubular organic anion transport.2005
- Author(s)
  Anzai N, Jutabha P, Kanai Y, Endou H.
- Journal Title
  
  Curr Opin Nephrol Hypertens. 14(5)
  
  Pages: 472-479
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Molecular physiology of urate transport.2005
- Author(s)
  Hediger MA, Johnson RJ, Miyazaki H, Endou H.
- Journal Title
  
  Physiology (Bethesda). 20
  
  Pages: 125-133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Mutations in human urate transporter 1 gene in presecretory reabsorption defect type of familial renal hypouricemia.2005
- Author(s)
  Wakida N, Tuyen do G, Adachi M, Miyoshi T, Nonoguchi H, Oka T, Ueda O, Tazawa M, Kurihara S, Yoneta Y, Shimada H, Oda T, Kikuchi Y, Matsuo H, Hosoyamada M, Endou H, Otagiri M, Tomita K, Kitamura K.
- Journal Title
  
  J Clin Endocrinol Metab. 90(4)
  
  Pages: 2169-2174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules.2005
- Author(s)
  Anzai N, Jutabha P, Enomoto A, Yokoyama H, Nonoguchi H, Hirata T, Shiraya K, He X, Cha SH, Takeda M, Miyazaki H, Sakata T, Tomita K, Igarashi T, Kanai Y, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther. 315(2)
  
  Pages: 534-544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction.2005
- Author(s)
  Villar SR, Brandoni A, Anzai N, Endou H, Torres AM.
- Journal Title
  
  Kidney Int. 68(6)
  
  Pages: 2704-2713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Neprhrin and podocin expression aroung the onset of puromycin aminonucleoside nephrosis.2005
- Author(s)
  Hosoyamada M, Yan K, Nishibori Y, Takiue Y, Kudo A, Kawkami H, Shibasaki T, Endou H
- Journal Title
  
  J.Pharmacol.Sci. 97
  
  Pages: 234-241
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules.2005
- Author(s)
  Anzai N, Jutabha P, Enomoto A, Yokoyama H, Nonoguchi H, Hirata T, Shiraya K, He X, Cha SH, Takeda M, Miyazaki H, Sakata T, Tomita K, Igarashi T, Kanai Y, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther. 315(2)
  
  Pages: 534-544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Mutations in human urate transporter 1 gene in presecretory reabsorption defect type of familial renal hypouricemia.2005
- Author(s)
  Wakida N, Tuyen do G, Adachi M, Miyoshi T, Nonoguchi H, Oka T, Ueda O, Tazawa M, Kurihara S, Yoneta Y, Shimada H, Oda T, Kikuchi Y, Matsuo H, Hosoyamada M, Endou H, Otagiri M, Tomita K, Kitamura K.
- Journal Title
  
  J Clin Endocrinol Metab. 90(4)
  
  Pages: 2169-2174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Qunatitative evaluation of the drug-drug interactions between methotrexate and nonsteroidal anti-inflammatory drug in the renal uptake process based on the contribution of organic anion transporters and reduced folate carrier.2004
- Author(s)
  Nozaki Y, Kusuhara H, Endou H, Sugiyama Y
- Journal Title
  
  J Pharmacol Exp Ther. 309(1)
  
  Pages: 226-234
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Carrier-mediated uptake of H2-receptor antagonists by the rat choroids plexus : involvement of rat organic anion transporter 3.2004
- Author(s)
  Nagata Y, Kusuhara H, Hirono S, Endou H, Sugiyama Y
- Journal Title
  
  Drug Metab.Dispos. 32
  
  Pages: 1040-1047
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The multispecific organic anion transporter family : properties and pharmacological significance.2004
- Author(s)
  Miyazaki H, Sekine T, Endou H
- Journal Title
  
  Trends Pharmacol Sci. 25(12)
  
  Pages: 654-662
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion.2004
- Author(s)
  Ichida K, Hosoyamada M, Hisatome I, Enomoto A, Hikita M, Endou H, Hosoya T
- Journal Title
  
  J Am Soc Neprol 15
  
  Pages: 164-173
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Involvement of multiple transporters in the efflux of 3-hydroxy-3-methylglutaryl-coA reductase inhibitors across the blood-brain barrier.2004
- Author(s)
  Kikuchi R, Kusuhara H, Abe T, Endou H, Sugiyama Y.
- Journal Title
  
  J Pharmacol Exp Ther 311(3)
  
  Pages: 1147-1153
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Mutation and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis.2004
- Author(s)
  Inatomi J, Horita S, Braverman N, Sekine T, Yamada H, Suzuki Y, Kawahara K, Moriyama N, Kudo A, Kawakami H, Ahimadzu M, Endou H, Fujita T, Seki G, Igarashi T
- Journal Title
  
  Pfluegers Arch-Eur.J.Physiol. 448
  
  Pages: 438-444
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Interactions of human organic anion transporters with diuretics.2004
- Author(s)
  Hasannejad H, Takeda M, Taki K, Shin HJ, Babu E, Jutabha P, Khamdang S, Aleboyeh M, Onozato ML, Tojo A, Enomoto A, Anzai N, Narikawa S, Huang XL, Niwa T, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther. 308(3)
  
  Pages: 1021-1029
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The SLC22 drug transporter family.2004
- Author(s)
  Koepsell H, Endou H.
- Journal Title
  
  Pflugers Arch. 44
  
  Pages: 666-676
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The multivalent PDZ-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.2004
- Author(s)
  Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H.
- Journal Title
  
  J Biol Chem. 279(44)
  
  Pages: 45942-45950
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Evidence for a role of human organic anion transporters in the muscular side effects of HMG-GoA reductase inhibitors.2004
- Author(s)
  Takeda M, Norshio R, Onozato ML, Tojo A, Hasannejad H, Hang XL, Narikawa S, Endou H.
- Journal Title
  
  Eur.J.Pharmacol. 483
  
  Pages: 133-138
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese.2004
- Author(s)
  Iwai N, Mino Y, Hosoyamada M, Tago N, Kokubo Y, Endou H.
- Journal Title
  
  Kidney Int. 66
  
  Pages: 935-944
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] A high prevalence of renal hypouricemia caused by inactive SLC22A12 in Japanese.2004
- Author(s)
  Iwai N, Mino Y, Hosoyamada M, Tago N, Kokubo Y, Endou H.
- Journal Title
  
  Kidney Int. 66
  
  Pages: 935-944
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Interactions of human organic anion transporters with diuretics.2004
- Author(s)
  Hasannejad H, Takeda M, Taki K, Jung SH, Babu F, Jutabha P, Khamdang S, Aleboyen M, Onodera ML, Tojo A, Enomoto A, Anzai N, Narikawa S, Huang XL, Niwa T, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther. 308(3)
  
  Pages: 1021-1029
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] The multispecific organic anion transporter family : properties and pharmacological significance.2004
- Author(s)
  Miyazaki H, Sekine T, Endou H
- Journal Title
  
  Trends Pharmacol Sci. 25(12)
  
  Pages: 654-662
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition.2004
- Author(s)
  Ljubojevic M, Herak-Kramberger CM, Hagos Y, Bahn A, Endou H, Burckhardt G, Sabolic I.
- Journal Title
  
  Am J Physiol Renal Physiol. 287(1)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane.2004
- Author(s)
  Nishibori Y, Liu L, Hosoyamada M, Endou H, Kudo A, Takenaka H, Higashihara E, Bessho F, Takahashi S, Kershaw D, Ruotsalainen V, Tryggvason K, Khoshnoodi J, Yan K
- Journal Title
  
  Kidney Int. 66
  
  Pages: 1755-1765
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Human organic anion transporter 4 is a renal apical organic anion / dicarboxylate exchanger in the proximal tubules.2004
- Author(s)
  Ekaratanawong S, Anzai N, Jutabha P, Miyazaki H, Moshiro R, Takeda M, Kanai, Endou, H.
- Journal Title
  
  Pharmacol Sci 94
  
  Pages: 297-304
- NAID
  130000073849
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Involvement of rat organic anion transporter 3 in the uptake of an organic herbicide, 2,4-dichlorophenoxyacetate, by the isolated rat choroids plexus.2004
- Author(s)
  Nagata Y, Kusuhara H, Imaoka T, Endou H., Sugiyama Y
- Journal Title
  
  J Pharm Sci 93(11)
  
  Pages: 2724-2732
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions.2004
- Author(s)
  Sakata T, Anzai N, Shin HJ, Noshiro R, Hirata T, Yokoyama H, Kanai Y, Endou H.
- Journal Title
  
  Biochem Biophys Res Commun. 313(3)
  
  Pages: 789-793
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Carrier-mediated uptake of H2-receptor antagonists by the rat choroids plexus : involvement of rat organic anion transporter 3.2004
- Author(s)
  Nagata Y, Kusuhara H, Hirono S, Endou H, Sugiyama Y
- Journal Title
  
  Drug Metab.Dispos. 32
  
  Pages: 1040-1047
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Human organic anion transporter 4 is a renal apical organis anion / dicarboxylate exchanger in the proximal tubules.2004
- Author(s)
  Ekaratanawong S, Anzai N, Jutabha P, Miyazaki H, Noshiro R, Takeda M, Kanai, Endou H.
- Journal Title
  
  Pharmacol Sci 94
  
  Pages: 297-304
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Expression and functional characterization of the system L amino acid transporter in KB human oral epidermoid carcinoma cells.2004
- Author(s)
  Yoon JH, Kim YB, Kim MS, Park JC, Cook JK, Kook KK, Jung HM, Kim SG, Yoo H, Ko YM, Lee SH, Kim BY, Chun HS, Kanai Y, Endou H, Kim DK
- Journal Title
  
  Cancer Lett. 205
  
  Pages: 215-226
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion.2004
- Author(s)
  Ichida K, Hosoyamada M, Hisatome I, Enomoto A, Hikita M, Endou H, Hosoya T
- Journal Title
  
  J Am Soc Neprol 15
  
  Pages: 164-173
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Expression and Functional characterization of the system L amino acid transporter in KB human oral epidermoid carcinoma cells.2004
- Author(s)
  Yoon J.H., Kim Y.B., Kim M.S., Park J.C., Kook J.K., Jung H.M., Kim S.G., Yoo H., Ko Y.M., Lee S.H., Kim B.Y., Chun H.S., Kanai Y., Endou H., Kim do K.
- Journal Title
  
  Cancer Lett 205
  
  Pages: 215-226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670836
[Journal Article] The SLC22 drug transporter family,2004
- Author(s)
  Koepsell H, Endou H.
- Journal Title
  
  Pflugers Arch. 447
  
  Pages: 666-676
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] 尿酸トランスポーターの分子実体2004
- Author(s)
  細山田真, 金井好克, 遠藤仁
- Journal Title
  
  Gout and Nucleic Acid Metabolism 28(1)
  
  Pages: 1-5
- NAID
  10014068515
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Mutation and functional analysis of SLC4A4 in a patient with proximal renal tubular acidosis.2004
- Author(s)
  Inatomi J, Horita S, Braverman N, Sekine T, Yamada H, Suzuki Y, Kawahara K, Moriyama N, Kudo A, Kawakami H, Shimadzu M, Endou H, Fujita T, Seki G, Igarashi T
- Journal Title
  
  Pfluegers Arch-Eur.J.Physiol. 448
  
  Pages: 438-444
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Interactions of human organic anion transporters with diuretics.2004
- Author(s)
  Hasanne jad H, Takeda M, Taki K, Shin HJ, Babu E, Jutabha P, Khamdang S, Aleboyeh M, Onozato ML, Tojo A, Enomoto A, Anzai N, Narikawa S, Huang XL, Niwa T, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther. 308(3)
  
  Pages: 1021-1029
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Expression of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (4F2hc) in oral squamous cell carcinoma and its precursor lesions.2004
- Author(s)
  Kim do K., Ahn S.G., Park J.C., Kanai Y., Endou H., Yoon J.H.
- Journal Title
  
  Anticancer Res 24
  
  Pages: 1671-1675
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670836
[Journal Article] Novel single nucleotide polymorphisms of organic cation transporter 1(SLC22A1) affecting transport functions.2004
- Author(s)
  Sakata T, Anzai N, Shin HJ, Norhiro R, Hirata T, Yokoyama H, Kanai Y, Endou H.
- Journal Title
  
  Biochem Biophys Res Comm. 313
  
  Pages: 789-793
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Novel single nucleotide polymorphisms of organic cation transporter 1(SLC22A1) affecting transport functions.2004
- Author(s)
  Sakata T, Anzai N, Shin HJ, Norhiro R, Hirata T, Yokoyama H, Kanai Y, Endou H.
- Journal Title
  
  Biochem Biophys Res comm. 313
  
  Pages: 789-793
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] CATs and HATs : the SLC7 family of amino acid transporters.2004
- Author(s)
  Verrey F, Closs EI, Wagner CA, Palacin M, Endou H, Kanai Y.
- Journal Title
  
  Pflugers Arch. 447
  
  Pages: 532-542
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Interactions of human organic anion transporters with diuretics.2004
- Author(s)
  Hasannejad H, Takeda M, Taki K, Jung SH, Babu E, Jutabha P, Khamdang S, Aleboyen M, Onodera ML, Tojo A, Enomoto A, Anzai N, Narikawa S, Huang XL, Niwa T, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther 308(3)
  
  Pages: 1021-1029
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Involvement of multiple transporters in the efflux of 3-hydroxy-3-methylglutaryl-coA reductase inhibitors across the blood-brain barrier.2004
- Author(s)
  Kikuchi R, Kusuara H, Abe T, Endou H, Sugiyama Y.
- Journal Title
  
  J Pharmacol Exp Ther 311(3)
  
  Pages: 1147-1153
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.2004
- Author(s)
  Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H
- Journal Title
  
  J Biol Chem 279(44)
  
  Pages: 45942-45950
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The multivalent PDZ-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.2004
- Author(s)
  Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H.
- Journal Title
  
  J Biol Chem. 279(44)
  
  Pages: 45942-45950
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Involvement of rat organic anion transporter 3 in the uptake of an organic herbicide, 2,4-dichlorophenoxycetate, by the isolated rat choroids plexus.2004
- Author(s)
  Nagata Y, Kusuhara H, Imaoka T, Endou H., Sugiyama Y
- Journal Title
  
  J Pharm Sci 93(1)
  
  Pages: 2724-2732
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The multispecific organic anion transporter family : properties and pharmacological significance.2004
- Author(s)
  Miyazaki H, Sekine T, Endou H.
- Journal Title
  
  Trends Pharmacol Sci. 25(12)
  
  Pages: 654-662
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Preferential expression of L-type amino acid transporter 1 in ameloblasts during rat tooth development.2004
- Author(s)
  Park JC, Kim YB, Yoon H, Kim HJ, Kim SN, Kanai Y, Endou H, Kim DK
- Journal Title
  
  Anat Histol Embryol 33
  
  Pages: 119-124
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Qunatitative evaluation of the drug-drug interactions between methotrexate and nonsteroidal anti-inflammatory drugs in the renal uptake process based on the contribution of organic anion transporters and reduced folate carrier.2004
- Author(s)
  Nozaki Y, Kusuhara H, Endou H, Sugiyama Y
- Journal Title
  
  J Pharmacol Exp Ther. 309(1)
  
  Pages: 226-234
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Function and localization of urate transporter 1 in mouse kidney.2004
- Author(s)
  Hosoyamada M, Ichida K, Enomoto A, Hosoya T, Endou H.
- Journal Title
  
  J Am Soc Nephrol. 15(2)
  
  Pages: 261-268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] 尿酸トランスポーターの分子実体2004
- Author(s)
  細山田真, 金井好克, 遠藤仁
- Journal Title
  
  Gout and Nucleic Acid Metabolism 28(1)
  
  Pages: 1-5
- NAID
  10014068515
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] The multispecific organic anion transporter family : properties and pharmacological significance.2004
- Author(s)
  Miyazaki H, Sekine T, Endou H.
- Journal Title
  
  Trends Pharmacol Sci. 25(12)
  
  Pages: 654-662
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Evidence for a role of human organic anion transporters in the muscular side effects of HMG-GoA reductase inhibitors.2004
- Author(s)
  Takeda M, Norshio R, Onozato ML, Tojo A, Hasannejad H, Hang XL, Narikawa S, Endou H.
- Journal Title
  
  Eur.J.Phamacol. 483
  
  Pages: 133-138
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions.2004
- Author(s)
  Sakata T, Anzai N, Shin HJ, Noshiro R, Hirata T, Yokoyama H, Kanai Y, Endou H.
- Journal Title
  
  Biochem Biophys Res Commun. 313(3)
  
  Pages: 789-793
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] System L-amino acid transporters are Differently expressed in rat astrocyte and C6 glioma cells.2004
- Author(s)
  Kim do K., Kim I.J., Hwang S., Kook J.H., Lee M.C., Shin B.A., Bae C.S., Yoon J.H., Ahn S.G., Kim S.A., Kanai Y., Endou H., Kim J.K.
- Journal Title
  
  Neurosci Res 50
  
  Pages: 437-446
- NAID
  10023901883
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670836
[Journal Article] Preferential expression of L-type amino acid transporter 1 in ameloblasts during rat tooth development.2004
- Author(s)
  Park J.C., Kim Y.B., Yoon J.H., Kim H.J., Kim S.M., Kanai Y., Endou H., Kim D.K.
- Journal Title
  
  Anat Histol Embryol 33
  
  Pages: 119-124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670836
[Journal Article] The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.2004
- Author(s)
  Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H
- Journal Title
  
  J Biol Chem 279(44)
  
  Pages: 45942-45950
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] CATs and HATs : the SLC7 family of amino acid transporters.2004
- Author(s)
  Verrey F, Closs EI, Wagner CA, Palacin M, Endou H, Kanai Y.
- Journal Title
  
  Pflugers Arch. 447
  
  Pages: 532-542
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition.2004
- Author(s)
  Ljubojevic M, Herak-Kramberger CM, Hagos Y, Bahn A, Endou H, Burckhardt G, Sabolic I.
- Journal Title
  
  Am J Physiol Renal Physiol. 287(1)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs.2004
- Author(s)
  Hassannejad H, Takeda M, Narikawa S, Huang XL, Enomoto A, Taki K, Niwa T, Shin HJ, Onozato ML, Tojo A, Endou H
- Journal Title
  
  Euro J Pharmacol. 499
  
  Pages: 45-51
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Expression and functional characterization of the system L amino acid trasporter in KB human oral epidermoid carcinoma cells.2004
- Author(s)
  Yoon JH, Kim YB, Kim MS, Park JC, Cook JK, Kook KK, Jung HM, Kim SG, Yoo H, Ko YM, Lee SH, KIM BY, Chun HS, Kanai Y, Endou H, Kim DK.
- Journal Title
  
  Cancer Lett. 205
  
  Pages: 215-226
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Preferential expression of L-type amino acid transporter 1 in ameloblasts during rat tooth development.2004
- Author(s)
  Park JC, Kim YB, Yoon H, Kim HJ, Kim SN, Kanai Y, Endou H, Kim DK
- Journal Title
  
  Anat Histol Embryol 33
  
  Pages: 119-124
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The genetic polymorphism of drub transporters : functional analysis approaches.2004
- Author(s)
  Ishikawa T, Tsuji A, Inui K, Sai Y, Anzai N, Wada M, Endou H, Sumino Y
- Journal Title
  
  Phamacogeneomics 5(1)
  
  Pages: 67-99
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs.2004
- Author(s)
  Hassannejad H, Takeda M, Narikawa S, Huang XL, Enomoto A, Taki K, Niwa T, Shin HJ, Onozato ML, Tojo A, Endou H
- Journal Title
  
  Euro J Pharmacol. 499
  
  Pages: 45-51
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Function and localization of urate transporter 1 in mouse kidney.2004
- Author(s)
  Hosoyamada M, Ichida K, Enomoto A, Hosoya T, Endou H.
- Journal Title
  
  J Am Soc Nephrol. 15(2)
  
  Pages: 261-268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] The genetic polymorphism of drub transporters : functional analysis approaches.2004
- Author(s)
  Ishikawa T, Tsuji A, Inui K, Sai Y, Anzai N, Wada M, Endou H, Sumino Y
- Journal Title
  
  Phamacogeneomics 5(1)
  
  Pages: 67-99
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Disease-causing missense mutations in NPHS2 gene alter normal nephrin trafficking to the plasma membrane.2004
- Author(s)
  Nishibori Y, Liu L, Hosoyamada M, Endou H, Kudo A, Takenaka H, Higashihara E, Bessho F, Takahashi S, Kershaw D, Ruotsalainen V, Tryggvason K, Khoshnodi J, Yan K
- Journal Title
  
  Kidney Int. 66
  
  Pages: 1755-1765
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Interactions of human organic anion as well as cation transporters with indoxyl sulfate.2003
- Author(s)
  Enomoto A, Takeda M, Taki K, Takayama F, Noshiro R, Niwa T, Endou H.
- Journal Title
  
  Eur J Pharmacol. 466(1-2)
  
  Pages: 13-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Functional properties of multispecific amino acid transporters and their implications to transporter-mediated toxicity.2003
- Author(s)
  Kanai Y, Endou H.
- Journal Title
  
  J Toxicol Sci. 28(1)
  
  Pages: 1-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule.2003
- Author(s)
  Jutabha P, Kanai Y, Hosoyamada M, Chairoungdua A, Kim do K, Iribe Y, Babu E, Kim JY, Anzai N, Chatsudthipong V, Endou H.
- Journal Title
  
  J Biol Chem. 278(30)
  
  Pages: 27930-27938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule.2003
- Author(s)
  Jutabha P, Kanai Y, Hosoyamada M, Chairoungdua A, Kim do K, Iribe Y, Babu E, Kim JY, Anzai N, Chatsudthipong V, Endou H.
- Journal Title
  
  J Biol Chem. 278(30)
  
  Pages: 27930-27938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters.2003
- Author(s)
  Babu E, Kanai Y, Chairoungdua A, Kim do K, Iribe Y, Tangtrongsup S, Jutabha P, Li Y, Ahmed N, Sakamoto S, Anzai N, Nagamori S, Endou H.
- Journal Title
  
  J Biol Chem. 278(44)
  
  Pages: 43838-43845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.2003
- Author(s)
  Khamdang S, Takeda M, Babu E, Noshiro R, Onozato ML, Tojo A, Enomoto A, Huang XL, Narikawa S, Anzai N, Piyachaturawat P, Endou H.
- Journal Title
  
  Eur J Pharmacol. 465(1-2)
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Urate transport via human PAH transporter hOAT1 and its gene structure.2003
- Author(s)
  Ichida K, Hosoyamada M, Kimura H, Takeda M, Utsunomiya Y, Hosoya T, Endou H.
- Journal Title
  
  Kidney Int. 63(1)
  
  Pages: 143-155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters.2003
- Author(s)
  Babu E, Kanai Y, Chairoungdua A, Kim do K, Iribe Y, Tangtrongsup S, Jutabha P, Li Y, Ahmed N, Sakamoto S, Anzai N, Nagamori S, Endou H.
- Journal Title
  
  J Biol Chem. 278(44)
  
  Pages: 43838-43845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Functional properties of multispecific amino acid transporters and their implications to transporter-mediated toxicity.2003
- Author(s)
  Kanai Y., Endou H.
- Journal Title
  
  J Toxicol Sci 28
  
  Pages: 1-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670836
[Journal Article] Functional properties of multispecific amino acid transporters and their implications to transporter-mediated toxicity.2003
- Author(s)
  Kanai Y, Endou H.
- Journal Title
  
  J Toxicol Sci. 28(1)
  
  Pages: 1-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Interactions of human organic anion as well as cation transporters with indoxyl sulfate.2003
- Author(s)
  Enomoto A, Takeda M, Taki K, Takayama F, Noshiro R, Niwa T, Endou H.
- Journal Title
  
  Eur J Pharmacol. 466(1-2)
  
  Pages: 13-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Urate transport via human PAH transporter hOAT1 and its gene structure.2003
- Author(s)
  Ichida K, Hosoyamada M, Kimura H, Takeda M, Utsunomiya Y, Hosoya T, Endou H.
- Journal Title
  
  Kidney Int. 63(1)
  
  Pages: 143-155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.2003
- Author(s)
  Khamdang S, Takeda M, Babu E, Noshiro R, Onozato ML, Tojo A, Enomoto A, Huang XL, Narikawa S, Anzai N, Piyachaturawat P, Endou H.
- Journal Title
  
  Eur J Pharmacol. 465(1-2)
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Immunolocalization of multispecific organic anion transporters, OAT1, OAT2 and OAT3 in rat kidney.2002
- Author(s)
  Kojima R, Sekine T, Kawachi M, Cha S.M., Suzuki Y, Endou H.
- Journal Title
  
  J Am Soc Nephrol. 13
  
  Pages: 848-857
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Identification of novel Na+-independent acidic amino acid transporter with structural similarity to the member of heterodimeric amino acid transporter family associated with unknown heavy chains.2002
- Author(s)
  Matsuo H, Kanai Y, Kim JY, Chairungdua A, Kim DK, Inatomi J, Shigeta, Y, Ishimine H, Chekuntode S, Tachampa K, Choi HW, Babu E, Fukuda J, Endou H.
- Journal Title
  
  J Biol Chem. 277
  
  Pages: 21017-21026
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Transport of amino acid-related compounds mediated by L-type amino acid transorter 1 (LAT1) : Insights into the mechanisms of substrate recognition.2002
- Author(s)
  Uchino H, Kanai Y, Kim DK, Wenpe MF, Chairoungdua A, Morimoto E, Anders MW, Endou H.
- Journal Title
  
  Mol Pharmacol. 61
  
  Pages: 729-737
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1) : Insights into the mechanisms of substrate recognition.2002
- Author(s)
  Uchino H, Kanai Y, Kim DK, Wenpe MF, Chairoungdua A, Morimoto E, Anders MW, Endou H.
- Journal Title
  
  Mol Pharmacol. 61
  
  Pages: 729-737
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Molecular identication of a novel carnitine transporter specific of human testis.2002
- Author(s)
  Enomoto A, Wempe MF, Tsuchida H, Shin HJ, Cha SH, Anzai N, Goto A, Sakamoto A, niwa T, Kanai Y, Anders MW, Endou H.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 36262-26271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] The human T-type amino acid transporter-1 ; Characterization, gene organization, and chromosomal location.2002
- Author(s)
  Kim DK, Kanai Y, Matsuo H, Kim JY, Chairoungdua A, Kobayashi Y, Enomoto A, Cha SH, Goya T, Endou H.
- Journal Title
  
  Genomics 79
  
  Pages: 95-103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The human T-type amino acid transporter-1 ; Characterization, gene organization, and chromosomal location.2002
- Author(s)
  Kim DK, Kanai Y, Matsuo H, Kim JY, Chairoungdua A, Kobayashi Y, Enomoto A, Cha SH, Goya T, Endou H.
- Journal Title
  
  Genomics 79
  
  Pages: 95-103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Identification of novel Na+-independent acidic amino acid transporter with structural similarity to the member of heterodimeric amino acid transporter family associated with unknown heavy chains.2002
- Author(s)
  Matsuo H, Kanai Y, Kim JY, Chairungdua A, Kim DK, Inatomi J, Shigeta, Y, Ishimine H, Chekuntode S, Tachampa K, Choi HW, Babu E, Fukuda J, Endou H.
- Journal Title
  
  J Biol Chem. 277
  
  Pages: 21017-21026
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Immunolocalization of multispecific organic anion transporters, OAT1, OAT2 and OAT3 in rat kidney.2002
- Author(s)
  Kojima R, Sekine T, Kawachi M, Cha S.M., Suzuki Y, Endou H.
- Journal Title
  
  J Am Soc Nephrol. 13
  
  Pages: 848-857
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Molecular identification of a renal urate-anion exchanger that regulates blood urate levels.2002
- Author(s)
  Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Cha SH, Hosoyamada M, Takeda M, Sekine T, Igarashi T, Matsuo H, Kikuchi Y, Oda T, Ichida K, Hosoya T, Shimokata K, Niwa T, Kanai Y, Endou H.
- Journal Title
  
  Nature 417
  
  Pages: 447-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Molecular identication of a novel carnitine transporter specific of human testis.2002
- Author(s)
  Enomoto A, Wempe MF, Tsuchida H, Shin HJ, Cha SH, Anzai N, Goto A, Sakamoto A, niwa T, Kanai Y, Anders MW, Endou H.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 36262-26271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Molecular identification of a renal urate-anion exchanger that regulates blood urate levels.2002
- Author(s)
  Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Cha SH, Hosoyamada M, Takeda M, Sekine T, Igarashi T, Matsuo H, Kikuchi Y, Oda T, Ichida K, Hosoya T, Shimokata K, Niwa T, Kanai Y, Endou H.
- Journal Title
  
  Nature 417
  
  Pages: 447-452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells.2002
- Author(s)
  Kim do K., Kanai Y., Choi H.W., Tangtrongsup S., Chairoungdua A., Babu E., Tachampa K., Anzai N., Iribe Y., Endou H.
- Journal Title
  
  Biochim Biophys Acta 1565
  
  Pages: 112-121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670836
[Journal Article] Human cystine/glutamate transporter : cDNA cloning and upregulation by oxidative stress in glioma cells.2001
- Author(s)
  Kim JY, Kanai Y, Chairoungdua A, Cha SH, Matsuo H, Kim DK, Inatomi J, Sawa. H, Ida Y, Endou H.
- Journal Title
  
  Biochem Biopys Acta 1512
  
  Pages: 335-344
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Human cystinuria-related transporter : Localization and functional characterization.2001
- Author(s)
  Mizoguchi K, Cha SH, Chairoungdua A, Kim DK, Shigeta Y, Matsuo H, Fukushima J, Awa Y, Akakura K, Goya T, Ito H, Endou H, Kanai Y.
- Journal Title
  
  Kidney Int. 59
  
  Pages: 1821-1833
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Identification and characterization of a novel member of the heterodimeric amino acid transporter family presumed to be associated with an unknown heavy chain.2001
- Author(s)
  Chairoungdua A, Kanai Y, Matsuo H, Inatomi J, Kim DK, Endou H
- Journal Title
  
  J Biol Chem. 276
  
  Pages: 49390-49399
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Characterizaion of organic anion transport inhibitors using cells stably expressing human organic anion tansporters.2001
- Author(s)
  Takeda M, Narikawa S, Hosoyamada M, Cha SH, Sekine T, Endou H.
- Journal Title
  
  Eur J Pharmacol. 419
  
  Pages: 113-120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.2001
- Author(s)
  Kim DK, Kanai Y, Chairoungdua A, Matsuo H, Cha SH, Endou H.
- Journal Title
  
  J Biol Chem. 276
  
  Pages: 17221-17228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.2001
- Author(s)
  Cha SH, Sekine T, Fukushima J, Kanai Y, Kobayashi Y, Goya T, Endou H.
- Journal Title
  
  Mol Pharmacol. 59
  
  Pages: 1277-1286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Patent] 中性アミノ酸とランスポーターによる癌の検出法及びそのためのキット
- Inventor(s)
  遠藤仁
- Industrial Property Rights Holder
  遠藤仁
- Industrial Property Number
  2004-076282
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Patent] 遠藤仁
- Inventor(s)
  遠藤仁
- Industrial Property Rights Holder
  特願2003-384863
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Patent] 血管障害や高血圧症の治療・予防剤、及びそのスクリーニング法
- Inventor(s)
  遠藤仁
- Industrial Property Rights Holder
  遠藤仁
- Industrial Property Number
  2003-384863
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Patent] 硫酸抱合体を選択的に輸送するトランスポーター及びその遺伝子
- Inventor(s)
  遠藤仁
- Industrial Property Rights Holder
  遠藤仁
- Industrial Property Number
  2002-070985
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Patent] 硫酸抱合体を選択的に輸送するトランスポーター及びその遺伝子
- Inventor(s)
  遠藤仁
- Industrial Property Rights Holder
  遠藤仁
- Industrial Property Number
  2002-070985
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Patent] 精巣型カルチニンとランスポーターとその遺伝子
- Inventor(s)
  遠藤仁
- Industrial Property Rights Holder
  遠藤仁
- Industrial Property Number
  2001-161212
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Patent] 中性アミノ酸トランスポーターによる癌の検出法及びそのためのキット
- Inventor(s)
  遠藤仁
- Industrial Property Rights Holder
  遠藤仁
- Industrial Property Number
  2004-076282
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13376004

1. KANAI Yoshikatsu (60204533)

# of Collaborated Projects: 16 results

# of Collaborated Products: 55 results
2. TAKEDA Michio (40255401)

# of Collaborated Projects: 15 results

# of Collaborated Products: 11 results
3. HOSOYAMADA Makoto (00291659)

# of Collaborated Projects: 13 results

# of Collaborated Products: 21 results
4. SEKINE Takashi (50255402)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
5. CHA Seok ho (50276200)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
6. KIM Do Kyung (40327474)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
7. INATOMI Jun (00311960)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
8. ANZAI Naohiko (70276054)

# of Collaborated Projects: 4 results

# of Collaborated Products: 34 results
9. INABA Yutaka (30010094)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. IGARASHI Takashi (70151256)

# of Collaborated Projects: 3 results

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11. CHIBA Momoko (80095819)

# of Collaborated Projects: 3 results

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12. IRIBE Yuji (20348618)

# of Collaborated Projects: 3 results

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13. TATE Naoko (00201955)

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14. MIZUNO Akiko (60255403)

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15. KOMATSU Yasuhiro (60195849)

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21. SUMALEE Nimm

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22. SUMALEE Nimmannit

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23. SAMAISUKUH Sophasan

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26. SAITO T (10048994)

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32. MATSUI Yasuhisa (40241575)

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38. 東原英二 (00092312)

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39. 長谷川誠 (70014107)

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40. 乾賢一 (70034030)

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41. 猿田享男 (70051571)

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42. 田島陽太郎 (30049796)

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43. VIPADA Chaovakul

# of Collaborated Projects: 1 results

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44. UDOM Chantharaksri

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45. CHAIRAT Shayakul

# of Collaborated Projects: 1 results

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46. SOMKIAT Vasuvattakul

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48. SANGA Nilwarangkur

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49. MURAI Yoshiro

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50. CHUMPOL Pholpramool

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52. UEDA Masatsugu

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53. WATTANACHAI スサエングラット

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54. WATTANACHAI Susaengrat

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56. SAーNGA Nilwa

# of Collaborated Projects: 1 results

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57. JUTAMAAD Sat

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58. PAWINEE Piya

# of Collaborated Projects: 1 results

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59. JUTAMAAD Satayavivad

# of Collaborated Projects: 1 results

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60. PAWINEE Piyachaturawat

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61. SAMAISUKH S

# of Collaborated Projects: 1 results

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62. JUTAMAAD Sa

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63. PAWINEE Piy

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64. CHUMPOL Pho

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65. SUMALEE Nim

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66. HEDIGEL Matthias a

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67. TROTTI David

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68. 宮嶋伸一郎

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69. 横山宏和

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Endou Hitoshi 遠藤 仁

ENDOU Hitoshi 遠藤 仁

Research Projects

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リバースオンコロジー;がん胎児性LAT1抑制薬による遺伝子変化の網羅的解析Principal Investigator

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がん特異中性アミノ酸トランスポーター(LAT1)の発現と制御機序Principal Investigator

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Development of novel anti-uricosuric agents based on the genomic strategy.Principal Investigator

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がん胎児性中性アミノ酸トランスポーター(LAT1)の発現と細胞のがん化機構と制御Principal Investigator

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Genetic Abnormality of Renal Proximal Tubule-Specific Transporters as Causes of Sudden Death Syndrome in South-Eastern AsiaPrincipal Investigator

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がん胎児性中性アミノ酸トランスポーター(LAT1)の発現と細胞のがん化機構と制御Principal Investigator

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Identification of transporter genes regulating systemic kinetics of drugs and foreign compounds and their genetic polymorphismPrincipal Investigator

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Molecular mechanisms of drug transport across cell membranePrincipal Investigator

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Endou Hitoshi 遠藤仁

ENDOU Hitoshi 遠藤仁