TATE Naoko 楯直子

… Alternative Names

楯直子タテナオコ

UTSUNOMIYA Naoko

宇都宮直子ウツノミヤナオコ

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Researcher Number	00201955
Other IDs
Affiliation (Current)	2023: 帝京大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021: 帝京大学, 薬学部, 教授 2012: 帝京大学, 薬学部, 教授 2009 – 2011: Musashino University, 薬学研究所, 教授 2003: Nippon Veterinary and Animal Science University, Veterinary, Associate, 獣医学部, 助教授 2001 – 2002: 日本獣医畜産大学, 獣医畜産学部, 助教授 1998: 杏林大, 医学部, 助手 1995 – 1998: Kyorin University, School of Medicine, 医学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related Except Principal Investigator General pharmacology / Biological pharmacy
Keywords	Principal Investigator アミノ酸 / トランスポーター / アルツハイマー病 / アミロイドβペプチド / 構造 / 腫瘍細胞 / T細胞 / 免疫 / システイン / マクロファージ … More / リンパ球 / 線維化 / 凝集 / D-アミノ酸 / アミロイドβペプチド(Aβ) / Aβフラグメント / アミロイドβペブチド / 老人斑 / 老年性脳疾患 / 物性 / 神経細胞毒性 / 神経細胞 / リーリン / 会合体 / 円偏光二色性 / 層構造 / neuron / Reelin / complex / structure / 異性化アミノ酸 / マルチリガンド受容体RAGE / 老化 / D-Asp … More Except Principal Investigator アミノ酸 / グルタミン酸 / 膜輸送 / トランスポーター / トランスポータ / クローニング / Transporter / Glutamate / Central nervous system / シスチン / 酸化的ストレス / cystine / 神経伝達物質 / 構造機能相関 / グルタミン酸トランスポータ / 輸送 / キメラ解析 / アレルギー・ぜんそく / 老化 / 薬学 / 細胞・組織 / アレルギー・喘息 / アレルギー・せんそく / 気道上皮細胞 / 中枢神経系 / 神経伝達 / 神経毒性 / 興奮毒性 / neuro transmission / neurotoxicity / excitotoxicity / membrane transport / 生体防御 / 輸送担体 / cDNAクローニング / 交換輸送 / amino acid / Oxidative Stress / Cloning / Protection / システイン / 中枢神経 / 分子薬理学 / 神経細胞 / グリオーマ / Membrane transport / amino acids / oxidative stress / cysteine / Molewlar Pharmawlogy / 有機アニオン / 有機アニオントランスポーター / パラアミノ馬尿酸 / エストロン硫酸 / オクラトキシンA / 有機カチオントランスポーター / カルニチントランスポーター / 多選択性基質認識 / 近位尿細管中間部 / ジカルボン酸 / ジカルボン酸トランスポーター / 薬物輸送 / organic anion / organic anion transporter / para-amino hippurate / estron sulfate / ochratoxin A / organic cation transporter / carnitine transporter / multispecific substrate recognition Less

アミロイドβペプチドの「老化」によるアルツハイマー病原性変化の解析Principal Investigator
- Principal Investigator
  
  楯直子
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Teikyo University
Bronchial epithelial cells as the targets of the therapy for refractory asthma of elderly patients.
- Principal Investigator
  
  YAMASHITA Naomi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Musashino University
The mechanism of amyloid fibril formation induced by D-amino acidsPrincipal Investigator
- Principal Investigator
  
  TATE Naoko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Musashino University
The Mechanism of the formation of Reelin complexPrincipal Investigator
- Principal Investigator
  
  TATE Naoko
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nippon Veterinary and Animal Science University
グルタミン酸トランスポータファミリーの基質透過とチャネル形成の分子機房の解明
- Principal Investigator
  
  金井好克
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyorin University
T細胞機能の酸化還元的制御に関わるアミノ酸トランスポーターの同定Principal Investigator
- Principal Investigator
  
  楯直子
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyorin University
New roprorective roles of amino acid transporrers
- Principal Investigator
  
  KANAI Yoshikatdu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Molecular cloning and functional expression of kidney-specific organic anionic drug transporters
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University School of Medicine
グルタミン酸トランスポータファミリーの構造機能相関の解析
- Principal Investigator
  
  KANAI Yoshikatsu
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyorin University
T細胞機能の酸化還元的制御に関わるアミノ酸トランスポーターの同定Principal Investigator
- Principal Investigator
  
  楯直子 (宇都宮直子)
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyorin University
Roles of glutamate transporters in the nervous system
- Principal Investigator
  
  KANAI Yoshikatsu
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyorin University
Molecular identification of cystine / glutamate exchanger
- Principal Investigator
  
  KANAI Yoshikatsu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University

All 2022 2021 2012 2011 2010 2009

All Journal Article Presentation Book

[Book] 薬学生の物理化学2021
- Author(s)
  楯　直子・平嶋尚英
- Total Pages
  270
- Publisher
  培風館
- Data Source
  KAKENHI-PROJECT-21K06498
[Journal Article] Physicochemical characterization of the G51D mutation of α-synuclein that is responsible for its severe cytotoxicity2021
- Author(s)
  Murata Takuya、Tochio Naoya、Utsunomiya-Tate Naoko
- Journal Title
  
  Neuroscience Letters
  
  Volume: 760 Pages: 136077-136077
- DOI
  10.1016/j.neulet.2021.136077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06498
[Journal Article] D-Ser containing hymanin shows promotion of fibril formation2012
- Author(s)
  Hayashi, K., Sasabe, J., Chiba, T., Aiso, S. and Utsunomiya-Tate, N
- Journal Title
  
  Amino Acids
  
  Volume: 42 Pages: 2293-2297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590080
[Journal Article] D-Ser-containing humanin shows promotion of fibril formation2012
- Author(s)
  Hayashi, K., Sasabe, J., Chiba, T., Aiso, S., Utsunomiya-Tate, N.
- Journal Title
  
  Amino Acids
  
  Volume: 42 Pages: 2293-2297
- DOI
  10.1088/0957-4484/22/20/205702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590080
[Journal Article] Controlled structure and properties of silicate nanoparticle networks for incorporation of biosystem components2011
- Author(s)
  Sakai-Kato, K., Hasegawa, T., Takaoka, A., Kato, M, Toyo'oka, T., Utsunomiya-Tate, N. and Kawanishi, T
- Journal Title
  
  Nanotechnology
  
  Volume: 22 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590080
[Journal Article] Collagen racemization and de@position on the lung of aged rats2010
- Author(s)
  Kasai A, Yamashita N, Utsunomiya-Tate N
- Journal Title
  
  Biochemistlry Insight
  
  Volume: 3 Pages: 25-33
- Data Source
  KAKENHI-PROJECT-22590075
[Journal Article] Collagen racemization and deposition in the lungs of aged rats2010
- Author(s)
  Kasai, A., Yamashita, N. and Utsunomiya-Tate, N
- Journal Title
  
  Biochemistry Insights
  
  Volume: 3 Pages: 25-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590080
[Journal Article] Stability of folding structure of Zic zinc finger proteins2009
- Author(s)
  Sakai-Kato, K., Umezawa, Y., Mikoshiba, K., Aruga, J. and Utsunomiya-Tate, N
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 384 Pages: 362-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590080
[Presentation] 変異型α-synuclein；30PおよびA53Eの線維形成プロセスの解析2022
- Author(s)
  村田拓哉、小嶋淳也、吉根直加、小澤雅史、楯　直子
- Organizer
  第142回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-21K06498
[Presentation] 家族性パーキンソン病を惹起する変異型α-synucleinの構造と線維形成の解析2021
- Author(s)
  村田拓哉、小嶋淳也、吉根直加、小澤雅史、楯　直子
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06498
[Presentation] D-アスパラギン酸含有アミロイドβペプチドの線維・凝集体形成および神経細胞毒性に関する解析2011
- Author(s)
  林周宏、大平麻里、楯直子
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会議場
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21590080
[Presentation] D-アスパラギン酸含有アミロイドβペプチドの線維・凝集体形成および神経細胞毒性に関する解析2011
- Author(s)
  林周宏、楯直子
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都国際会館(京都)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21590080
[Presentation] 正常型HumaninおよびD-Ser含有Humaninの構造・物性に関する研究2011
- Author(s)
  林周宏、楯直子
- Organizer
  日本薬学会第131回年会
- Place of Presentation
  ツインメッセ静岡(静岡)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590080
[Presentation] Preferential domain orientation in HMGB2 protein revealed by NMR spectroscopy2010
- Author(s)
  Uewaki, J., and Utsunomiya-Tate, N
- Organizer
  PACIFICHEM2010
- Place of Presentation
  Honolulu, USA
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-21590080
[Presentation] アミロイドβペプチドのアスパラギン酸残基異性化置換による線維化・凝集機構における構造機能相関解析2010
- Author(s)
  楯直子
- Organizer
  日本生化学会第83回大会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21590080
[Presentation] D-Asp含有改変型アミロイドβペプチドの神経細胞毒性に関する研究2010
- Author(s)
  楯直子
- Organizer
  日本薬学会第130回年会
- Place of Presentation
  岡山大学(岡山県)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21590080
[Presentation] Analysis of structure stability of HMGB22009
- Author(s)
  森内寛、楯直子
- Organizer
  日本生物物理学会第47回年会
- Place of Presentation
  アクティ徳島(徳島)
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21590080
[Presentation] Influence of amino acid isomerization on proteins, which cause senescence-related diseases2009
- Author(s)
  Moriuchi, H. and Utsunomiya-Tate, N
- Organizer
  The 1^<st> international conference of D-amino acid research
- Place of Presentation
  Awaji Yumebutai International Conference Center(Awaji, Hyougo, Japan)
- Year and Date
  2009-07-02
- Data Source
  KAKENHI-PROJECT-21590080

1. KANAI Yoshikatsu (60204533)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. ENDOU Hitoshi (20101115)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. TAKEDA Michio (40255401)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HOSOYAMADA Makoto (00291659)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SEKINE Takashi (50255402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. HEDIGER Matt

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YAMASHITA Naomi (20239974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. TAKAHASHI Naoyuki (20337447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. CHA Seok ho (50276200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. INATOMI Jun (00311960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NUSSBERGER Stephan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HEDIGEL Matthias a

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TROTTI David

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TATE Naoko 楯 直子

楯 直子 タテ ナオコ

UTSUNOMIYA Naoko

宇都宮 直子 ウツノミヤ ナオコ

Research Projects

Research Products

Co-Researchers

アミロイドβペプチドの「老化」によるアルツハイマー病原性変化の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Bronchial epithelial cells as the targets of the therapy for refractory asthma of elderly patients.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of amyloid fibril formation induced by D-amino acidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Mechanism of the formation of Reelin complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

グルタミン酸トランスポータファミリーの基質透過とチャネル形成の分子機房の解明

Principal Investigator

Project Period (FY)

Research Category

Research Institution

T細胞機能の酸化還元的制御に関わるアミノ酸トランスポーターの同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New roprorective roles of amino acid transporrers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular cloning and functional expression of kidney-specific organic anionic drug transporters

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

グルタミン酸トランスポータファミリーの構造機能相関の解析

Principal Investigator

Project Period (FY)

Research Category

Research Institution

T細胞機能の酸化還元的制御に関わるアミノ酸トランスポーターの同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of glutamate transporters in the nervous system

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Molecular identification of cystine / glutamate exchanger

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 薬学生の物理化学2021

Author(s)

Total Pages

Publisher

TATE Naoko 楯直子

楯直子タテナオコ

宇都宮直子ウツノミヤナオコ