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TATE Naoko  楯 直子

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… Alternative Names

楯 直子  タテ ナオコ

UTSUNOMIYA Naoko

宇都宮 直子  ウツノミヤ ナオコ

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Researcher Number 00201955
Other IDs
Affiliation (Current) 2023: 帝京大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2021: 帝京大学, 薬学部, 教授
2012: 帝京大学, 薬学部, 教授
2009 – 2011: Musashino University, 薬学研究所, 教授
2003: Nippon Veterinary and Animal Science University, Veterinary, Associate, 獣医学部, 助教授
2001 – 2002: 日本獣医畜産大学, 獣医畜産学部, 助教授
1998: 杏林大, 医学部, 助手
1995 – 1998: Kyorin University, School of Medicine, 医学部, 助手
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological pharmacy / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
Except Principal Investigator
General pharmacology / Biological pharmacy
Keywords
Principal Investigator
アミノ酸 / トランスポーター / アルツハイマー病 / アミロイドβペプチド / 構造 / 腫瘍細胞 / T細胞 / 免疫 / システイン / マクロファージ … More / リンパ球 / 線維化 / 凝集 / D-アミノ酸 / アミロイドβペプチド(Aβ) / Aβフラグメント / アミロイドβペブチド / 老人斑 / 老年性脳疾患 / 物性 / 神経細胞毒性 / 神経細胞 / リーリン / 会合体 / 円偏光二色性 / 層構造 / neuron / Reelin / complex / structure / 異性化アミノ酸 / マルチリガンド受容体RAGE / 老化 / D-Asp … More
Except Principal Investigator
アミノ酸 / グルタミン酸 / 膜輸送 / トランスポーター / トランスポータ / クローニング / Transporter / Glutamate / Central nervous system / シスチン / 酸化的ストレス / cystine / 神経伝達物質 / 構造機能相関 / グルタミン酸トランスポータ / 輸送 / キメラ解析 / アレルギー・ぜんそく / 老化 / 薬学 / 細胞・組織 / アレルギー・喘息 / アレルギー・せんそく / 気道上皮細胞 / 中枢神経系 / 神経伝達 / 神経毒性 / 興奮毒性 / neuro transmission / neurotoxicity / excitotoxicity / membrane transport / 生体防御 / 輸送担体 / cDNAクローニング / 交換輸送 / amino acid / Oxidative Stress / Cloning / Protection / システイン / 中枢神経 / 分子薬理学 / 神経細胞 / グリオーマ / Membrane transport / amino acids / oxidative stress / cysteine / Molewlar Pharmawlogy / 有機アニオン / 有機アニオントランスポーター / パラアミノ馬尿酸 / エストロン硫酸 / オクラトキシンA / 有機カチオントランスポーター / カルニチントランスポーター / 多選択性基質認識 / 近位尿細管中間部 / ジカルボン酸 / ジカルボン酸トランスポーター / 薬物輸送 / organic anion / organic anion transporter / para-amino hippurate / estron sulfate / ochratoxin A / organic cation transporter / carnitine transporter / multispecific substrate recognition Less
  • Research Projects

    (12 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (13 People)
  •  アミロイドβペプチドの「老化」によるアルツハイマー病原性変化の解析Principal Investigator

    • Principal Investigator
      楯 直子
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Teikyo University
  •  Bronchial epithelial cells as the targets of the therapy for refractory asthma of elderly patients.

    • Principal Investigator
      YAMASHITA Naomi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Musashino University
  •  The mechanism of amyloid fibril formation induced by D-amino acidsPrincipal Investigator

    • Principal Investigator
      TATE Naoko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Musashino University
  •  The Mechanism of the formation of Reelin complexPrincipal Investigator

    • Principal Investigator
      TATE Naoko
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Nippon Veterinary and Animal Science University
  •  グルタミン酸トランスポータファミリーの基質透過とチャネル形成の分子機房の解明

    • Principal Investigator
      金井 好克
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyorin University
  •  T細胞機能の酸化還元的制御に関わるアミノ酸トランスポーターの同定Principal Investigator

    • Principal Investigator
      楯 直子
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyorin University
  •  New roprorective roles of amino acid transporrers

    • Principal Investigator
      KANAI Yoshikatdu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      General pharmacology
    • Research Institution
      Kyorin University
  •  Molecular cloning and functional expression of kidney-specific organic anionic drug transporters

    • Principal Investigator
      ENDOU Hitoshi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kyorin University School of Medicine
  •  グルタミン酸トランスポータファミリーの構造機能相関の解析

    • Principal Investigator
      KANAI Yoshikatsu
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyorin University
  •  T細胞機能の酸化還元的制御に関わるアミノ酸トランスポーターの同定Principal Investigator

    • Principal Investigator
      楯 直子 (宇都宮 直子)
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyorin University
  •  Roles of glutamate transporters in the nervous system

    • Principal Investigator
      KANAI Yoshikatsu
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kyorin University
  •  Molecular identification of cystine / glutamate exchanger

    • Principal Investigator
      KANAI Yoshikatsu
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kyorin University

All 2022 2021 2012 2011 2010 2009

All Journal Article Presentation Book

  • [Book] 薬学生の物理化学2021

    • Author(s)
      楯 直子・平嶋 尚英
    • Total Pages
      270
    • Publisher
      培風館
    • Data Source
      KAKENHI-PROJECT-21K06498
  • [Journal Article] Physicochemical characterization of the G51D mutation of α-synuclein that is responsible for its severe cytotoxicity2021

    • Author(s)
      Murata Takuya、Tochio Naoya、Utsunomiya-Tate Naoko
    • Journal Title

      Neuroscience Letters

      Volume: 760 Pages: 136077-136077

    • DOI

      10.1016/j.neulet.2021.136077

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K06498
  • [Journal Article] D-Ser containing hymanin shows promotion of fibril formation2012

    • Author(s)
      Hayashi, K., Sasabe, J., Chiba, T., Aiso, S. and Utsunomiya-Tate, N
    • Journal Title

      Amino Acids

      Volume: 42 Pages: 2293-2297

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Journal Article] D-Ser-containing humanin shows promotion of fibril formation2012

    • Author(s)
      Hayashi, K., Sasabe, J., Chiba, T., Aiso, S., Utsunomiya-Tate, N.
    • Journal Title

      Amino Acids

      Volume: 42 Pages: 2293-2297

    • DOI

      10.1088/0957-4484/22/20/205702

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Journal Article] Controlled structure and properties of silicate nanoparticle networks for incorporation of biosystem components2011

    • Author(s)
      Sakai-Kato, K., Hasegawa, T., Takaoka, A., Kato, M, Toyo'oka, T., Utsunomiya-Tate, N. and Kawanishi, T
    • Journal Title

      Nanotechnology

      Volume: 22 Pages: 1-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Journal Article] Collagen racemization and de@position on the lung of aged rats2010

    • Author(s)
      Kasai A, Yamashita N, Utsunomiya-Tate N
    • Journal Title

      Biochemistlry Insight

      Volume: 3 Pages: 25-33

    • Data Source
      KAKENHI-PROJECT-22590075
  • [Journal Article] Collagen racemization and deposition in the lungs of aged rats2010

    • Author(s)
      Kasai, A., Yamashita, N. and Utsunomiya-Tate, N
    • Journal Title

      Biochemistry Insights

      Volume: 3 Pages: 25-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Journal Article] Stability of folding structure of Zic zinc finger proteins2009

    • Author(s)
      Sakai-Kato, K., Umezawa, Y., Mikoshiba, K., Aruga, J. and Utsunomiya-Tate, N
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 384 Pages: 362-365

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Presentation] 変異型α-synuclein;30PおよびA53Eの線維形成プロセスの解析2022

    • Author(s)
      村田拓哉、小嶋淳也、吉根直加、小澤雅史、楯 直子
    • Organizer
      第142回日本薬学会年会
    • Data Source
      KAKENHI-PROJECT-21K06498
  • [Presentation] 家族性パーキンソン病を惹起する変異型α-synucleinの構造と線維形成の解析2021

    • Author(s)
      村田拓哉、小嶋淳也、吉根直加、小澤雅史、楯 直子
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K06498
  • [Presentation] D-アスパラギン酸含有アミロイドβペプチドの線維・凝集体形成および神経細胞毒性に関する解析2011

    • Author(s)
      林周宏、大平麻里、楯直子
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Presentation] D-アスパラギン酸含有アミロイドβペプチドの線維・凝集体形成および神経細胞毒性に関する解析2011

    • Author(s)
      林周宏、楯直子
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      京都国際会館(京都)
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Presentation] 正常型HumaninおよびD-Ser含有Humaninの構造・物性に関する研究2011

    • Author(s)
      林周宏、楯直子
    • Organizer
      日本薬学会第131回年会
    • Place of Presentation
      ツインメッセ静岡(静岡)
    • Year and Date
      2011-03-29
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Presentation] Preferential domain orientation in HMGB2 protein revealed by NMR spectroscopy2010

    • Author(s)
      Uewaki, J., and Utsunomiya-Tate, N
    • Organizer
      PACIFICHEM2010
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2010-12-18
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Presentation] アミロイドβペプチドのアスパラギン酸残基異性化置換による線維化・凝集機構における構造機能相関解析2010

    • Author(s)
      楯直子
    • Organizer
      日本生化学会第83回大会
    • Place of Presentation
      神戸ポートアイランド(兵庫)
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Presentation] D-Asp含有改変型アミロイドβペプチドの神経細胞毒性に関する研究2010

    • Author(s)
      楯直子
    • Organizer
      日本薬学会第130回年会
    • Place of Presentation
      岡山大学(岡山県)
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Presentation] Analysis of structure stability of HMGB22009

    • Author(s)
      森内寛、楯直子
    • Organizer
      日本生物物理学会第47回年会
    • Place of Presentation
      アクティ徳島(徳島)
    • Year and Date
      2009-10-30
    • Data Source
      KAKENHI-PROJECT-21590080
  • [Presentation] Influence of amino acid isomerization on proteins, which cause senescence-related diseases2009

    • Author(s)
      Moriuchi, H. and Utsunomiya-Tate, N
    • Organizer
      The 1^<st> international conference of D-amino acid research
    • Place of Presentation
      Awaji Yumebutai International Conference Center(Awaji, Hyougo, Japan)
    • Year and Date
      2009-07-02
    • Data Source
      KAKENHI-PROJECT-21590080
  • 1.  KANAI Yoshikatsu (60204533)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  ENDOU Hitoshi (20101115)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  TAKEDA Michio (40255401)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  HOSOYAMADA Makoto (00291659)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  SEKINE Takashi (50255402)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  HEDIGER Matt
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  YAMASHITA Naomi (20239974)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  TAKAHASHI Naoyuki (20337447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  CHA Seok ho (50276200)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  INATOMI Jun (00311960)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  NUSSBERGER Stephan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  HEDIGEL Matthias a
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TROTTI David
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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