Anzai Naohiko 安西尚彦

… Alternative Names

ANZAI Naohiko 安西尚彦

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Researcher Number	70276054
Other IDs	https://orcid.org/0000-0003-0605-0458
External Links
Affiliation (Current)	2023: 千葉大学, 大学院医学研究院, 教授
Affiliation (based on the past Project Information) *help	2015 – 2023: 千葉大学, 大学院医学研究院, 教授 2015: 千葉大学, 医学(系)研究科(研究院), 教授 2015: 千葉大学, 医学部, 教授 2011 – 2015: 獨協医科大学, 医学部, 教授 2012: 杏林大学、獨協医科大学, 医学部, 准教授(H22)、教授(H23~) … More 2009 – 2010: Kyorin University, 医学部, 准教授 2009: 杏林大学, 医学部, 講師 2006 – 2007: 杏林大学, 医学部, 講師 2006: 杏林大学・医学部 2002 – 2006: Kyorin Univ. School of Medicine, Assistant, 医学部, 助手 1996 – 2000: 北里大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / General pharmacology / Medium-sized Section 48:Biomedical structure and function and related fields / Basic Section 56030:Urology-related / Basic Section 53040:Nephrology-related / Biological Sciences / General physiology Except Principal Investigator Applied pharmacology / Kidney internal medicine / Biological Sciences … More / Basic Section 59040:Nutrition science and health science-related / General pharmacology / 応用薬理学・医療系薬学 / General physiology / General pharmacology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 48030:Pharmacology-related / Basic Section 48020:Physiology-related / Radiation science / Basic Section 56030:Urology-related / Basic Section 48040:Medical biochemistry-related / Basic Section 53030:Respiratory medicine-related / Basic Section 56040:Obstetrics and gynecology-related / General internal medicine and related fields / Basic Section 55020:Digestive surgery-related / Basic Section 42030:Animal life science-related / Urology / Gastroenterology / Cardiovascular surgery Less
Keywords	Principal Investigator トランスポーター / 腎臓 / 高尿酸血症 / 分子標的創薬 / PDZ / COX-2 / PDZ proteins / PDZタンパク質 / 創薬 / 痛風 … More / 尿酸 / 分子キラリティ / AI / リキッドバイオプシー / 泌尿器科がん / Transporter / Anions / Cyclooxigenase / Kidney / Prostaglandin / アニオン / シクロオキシゲナーゼ / プロスタグラジン / Surface biotinylation assay / Surface plasmon resonance / GST pull dow assay / Co-immunoprecipitation / Urate transporter / Yeast Two-hybrid assay / 近位尿細管 / 表面ビオチン化法 / 表面プラズモン共鳴法 / GSTプルダウンアッセイ / 共免疫沈降法 / 尿酸トランスポーター / 酵母Two-hybrid法 / 膜輸送 / 翻訳後修飾 / 細胞膜輸送 / 尿酸降下薬 / 腎臟 / テトラヒドロビオプテリン / 蛋白質 / 遺伝子 / 薬理学 / 腎尿細管 / 治療効果判定 / 腫瘍診断 / LAT2 / イムノアッセイ / 定量PCR / LAT1 / アミノ酸トランスポーター / コルヒチン / サイトカラシン / バソプレッシン / 高浸透圧 / 尿素 / 腎髄質内層集合管 / 遺伝子発現 / 尿素輸送体 … More Except Principal Investigator トランスポーター / アミノ酸トランスポーター / 尿酸 / LAT1 / rBAT / BAT1 / 痛風 / URAT1 / 1,5-アンヒドログルシトール / 前立腺がん / 去勢抵抗性 / 前立腺癌 / 造影剤 / 薬理学 / transporter / 輸送体 / SLC / アミノ酸 / ゲノム / PDZK1 / genetic factor / renal stones / ナトリウム / 環境因子 / 遺伝因子 / 尿路結石 / 重炭酸イオン共輸送体 / シスチン尿症 / 近位尿細管性アシドーシス / Kir7.1 / ROMK1 / ROMK2 / 遺伝子変異 / 薬物輸送 / 腎臓 / 蛋白質間相互作用 / シグナル伝達 / 4F2hc / LAT2 / K^+チャネル / 骨腫瘍 / ガドリニウム / 中性子補足療法 / 乳酸 / アストロサイト / 虚血耐性 / 低栄養 / 体液 / 高齢 / バソプレシン / 肝臓 / アシアロ糖蛋白受容体 / 抗酸化作用 / 膵外分泌 / インスリン分泌 / オルガンバス実験 / Liquid Biopsy / CRPC / cfDNA / ARV7 / LAT3 / L型アミノ酸トランスポーター / スプライシング / 尿酸取り込み実験 / 全ゲノム関連解析 / 佐渡PROSTコホート / ながはまコホート / レアバリアント / カーネル / 統計検定 / まれな変異 / 地域差 / コホート研究 / 遺伝率 / 尿酸値 / SU5416 / 肺動脈性肺高血圧症 / 骨髄移植 / 緑色蛍光タンパク質（GFP）発現ラット / 肺移植 / 血管内皮前駆細胞（EPCs） / 肺動脈性肺高血圧症（PAH） / 酸化的リン酸化阻害剤 / 糖代謝 / sgRNAスクリーニング / 癌代謝 / インスリン抵抗性 / メトホルミン / 肥満 / 子宮体癌 / 治療効果比 / 放射線治療 / BPA / ホウ素中性子補足療法 / LAT2阻害剤 / L-アミノ酸トランスポーター / LAT / ホウ素中性子捕捉療法 / Precision medicine / 近赤外線イメージ / 膵臓癌 / 血小板 / 腫瘍進展 / 癌間質 / 血管内凝固 / 浸潤 / 近赤外線 / 膵癌 / SLCトランスポーター / Slc22a14 / SLC22A14 / 受精能獲得 / 精子 / マウス / 生体分子 / 有機工業化学 / 癌 / 構造活性相関 / 阻害化合物 / マーカー / メタボロミクス / タンパク質 / 血清 / バイオバンク / AR増幅 / cf DNA / 予後 / 血清テストステロン / メタボローム / テストステロン / scaffold protein / Functional regulation / membrane targeting / amino acid / Protein-protein interaction / membrane protein / Pharmacology / 足場タンパク質 / 活性制御 / 細胞膜移行 / 膜蛋白質 / Anti-arrhythmia / Diuretics / Organic cation transport / Kidney / Drug transport / Organic anion transport / 抗不整脈薬 / 利尿薬 / 有機カチオン輸送 / 有機アニオン輸送 / epithelial transport / Heterodimeric protein / postgenome / genome / membrane transport / Amino acid / ヘテロ二量体型タンパク質 / ポストゲノム / 細胞膜輸送 / gout / Organic anion transporter / Hyperuricemia / Familial renal hypouricemia / ベンズブロマロン / ベンズプロマロン / PDZK 1 / イーストツーハイブリド法 / 特発性低尿酸血症 / 尿酸トランスポーター / 有機アニオントランスポーター / 高尿酸血症 / 家族性腎性低尿酸血症 / environmental factor / Sodium-bicarbonate cotransporter / Cystinuria / Proximal tubular acidosis / rBATl / BATl / 近位尿再管性アシドーシス / Na+ / Sertoli cell / Epididymis / SNP / Uric acid / Idopathic renal hypouricemia / Carnitine / Cation transporter / Anion transporter / デヒドロエピアンドロステロン硫酸 / エストロン硫酸 / エクソン / イントロン / 一塩基変異遺伝子多型 / パラアミノ馬尿酸 / 突発性腎性低尿酸血症 / 胎盤 / セルトリ細胞 / 精巣上体 / 一塩基変異遺伝子 / 特発性腎性低尿酸血症 / カルニチン / カチオントランスポーター / アニオントランスポーター / rats / potassium load / congenital heart failure / cardiac infarction / potassium channel / cycloheximide / ウエスタンブロット / 高浸透圧 / NKCC1 mRNA / 腎髄質内層集合管 / K^+負荷ラット / 心筋梗塞ラット / ラット / K+負荷 / うっ血性心不全 / 心筋梗塞 / K+チャネル / renal proximal tubule / Diabetes Mellitus / neonatal rats / glucocorticoid / Na^+-independent glucose transporter / Na^+-dependent glucose transporter / 腎近位尿細管 / 糖尿病 / 新生児ラット / 糖質コルチコイド / Na^+非依存性グルコース輸送体 / Na^+依存性グルコース輸送体 / GLUT10 / グルコーストランスポーター / 動脈屈曲症候群 / アミノ酸欠乏ストレス反応 / アミノ酸欠乏ストレス応答 / T細胞 / 尿酸降下薬 / 有機酸 / HK-2細胞 / 腎尿細管 / コネキシン / 蛋白質相互作用 / 細胞・組織 / タンパク質相互作用 / ギャップ結合 / 薬物代謝酵素 / 細胞内極性輸送 / 極性発現 / 運動後急性腎不全 / 尿酸輸送体 / 腎臓学 / 腎 / PDZタンパク質 / 上皮輸送 / 生体膜 / 複合体 / 膜輸送 / PI3kinase / mTOR / 細胞増殖 / 酵母two-hybrid法 / CD98 / 必須アミノ酸 / 癌治療法 / トランスポーター抑制薬 / BCH / LAT1抑制薬 / 中性アミノ酸トランスポーター / ミトコンドリア / ミネラルコルチコイド / Na^+輸送 / 腎集合管 / 共役蛋白 / K^+ ATPase / Na^+ / イオン輸送機能 / ウエスタンブロット法 / 免疫組織法 / ATP感受性Kチャネル Less

Evaluation of the Effect of Neutron Capture Therapy Using a Novel Gadolinium Preparation on Metastatic Bone Tumors
- Principal Investigator
  
  松川岳久
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Juntendo University
消化器官における糖代謝の調節因子としてみた1,5-AG機能の解明：加齢随伴性を念頭に
- Principal Investigator
  
  大内基司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Chiba University
高齢時の体液貯留かつ低栄養を惹起する鍵分子はバソプレシンなのか？
- Principal Investigator
  
  橋本弘史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Chiba University
脳虚血耐性におけるアストロサイト由来乳酸の役割の解明
- Principal Investigator
  
  平山友里
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Chiba University
Transporter-targeted drug development against urological cancers by utilizing liquid biopsy and AIPrincipal Investigator
- Principal Investigator
  
  安西尚彦
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Chiba University
Development of new BNCT sensitizer based on molecular chirality recognition of amino acid transporter LATPrincipal Investigator
- Principal Investigator
  
  安西尚彦
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Chiba University
ながはまコホートおよび佐渡コホートのゲノム情報解析による、尿酸値関連変異の探索
- Principal Investigator
  
  三澤計治
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Yokohama City University
  Kansai Medical University
Establishment of aminoacid transporter directed prostate cancer therapy based on the liquid biopsy
- Principal Investigator
  
  坂本信一
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Chiba University
抗酸化作用を介した膵内外分泌から紐解く食品含有1,5-AGの生理機能
- Principal Investigator
  
  大内基司
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Dokkyo Medical University
Elucidation of abnormal metabolic profile of endometrial cancer
- Principal Investigator
  
  Mitsuhashi Akira
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Chiba University
The study of pulmonary arterial hypertension with lung and bone marrow transplantation by GFP expressing rats
- Principal Investigator
  
  Sakao Seiichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Chiba University
Development of research on SLC transporters important for sperm function: Toward drug discovery and elucidation of the mechanism of fertility acquisition
- Principal Investigator
  
  Keiichiro Yogo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Shizuoka University
New drug development targeting novel renal tubular rate transporter MCT9 based on the structure-activity relationshipPrincipal Investigator
- Principal Investigator
  
  ANZAI Naohiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Chiba University
Development of precision medicine for pancreatic cancer combining near infrared imaging and biological information
- Principal Investigator
  
  Yoshitomi Hideyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Dokkyo Medical University
  Chiba University
Development of the new diagnostic method and drug discovery based on metabolic loam analysis of the castration-resistant prostate cancer
- Principal Investigator
  
  Sakamoto Shinichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Chiba University
Development of specific inhibitor against tumor-type amino acid transporter LAT3 and analysis for its pathophysiological role
- Principal Investigator
  
  JUTABHA Promsuk
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Dokkyo Medical University
Improvement of BNCT therapeutic gain based on selective protection of normal cells by LAT 2 inhibitor
- Principal Investigator
  
  Hirose Katsumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  General internal medicine and related fields
- Research Institution
  Southen Tohoku Research Institute for Neuroscience
Development of a New Dual Excretion Iodine-Based X-ray Contrast Agent with Hepatocyte Contrast Function
- Principal Investigator
  
  Matsumoto Nobuyuki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  St. Marianna University School of Medicine
Evaluation of 3-factor model (3F) of renal urate transport that may avoid less side-effect of druf-induced hyperuricemia.Principal Investigator
- Principal Investigator
  
  Anzai Naohiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Chiba University
  Dokkyo Medical University
Development of a new Iodine contrast agent excreted into bile and urine based on the transporter selectivity
- Principal Investigator
  
  Matsumoto Nobuyuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  St. Marianna University School of Medicine
Analysis of disease-onset by identifying the transport substrate for Arterial Tortuosity Syndrome (ATS) disease gene GLUT10
- Principal Investigator
  
  Fukuda Hirotsugu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Dokkyo Medical University
Role of LAT1 in T cell activation
- Principal Investigator
  
  HAYASHI Keitaro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Dokkyo Medical University
Molecular target of urate-lowering drugs: Identification and functional characterization of a novel renal urate transporter URAT2
- Principal Investigator
  
  JUTABHA Promsuk
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Dokkyo Medical University
Novel regulatory mechanism of renaltubular transporter function by SUMOylation-deSUMOylationPrincipal Investigator
- Principal Investigator
  
  ANZAI Naohiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Dokkyo Medical University
Elucidation of drug transporting route - association between transporters and gap junction -
- Principal Investigator
  
  MIURA Daisaku
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Hyogo University of Health Sciences
New drug development for hyperuricemia targeting novel urate efflux transporter URATv1Principal Investigator
- Principal Investigator
  
  ANZAI Naohiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Dokkyo Medical University
  Kyorin University
ベンズブロマロン感受性を指標とした腎尿細管テトラヒドロビオプテリン輸送体の探索Principal Investigator
- Principal Investigator
  
  安西尚彦
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
Changing of intracellular trafficking in polarized cells and regulation of serum urate level by the splicing variants of urate transporter URATv1.
- Principal Investigator
  
  KIMURA Toru
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
Elucidation of mechanism for exercise-induced acute renal failure in urate transporter deficient mice
- Principal Investigator
  
  ICHIDA Kimiyoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo University of Pharmacy and Life Science
Role of a novel prostaglandin transporter OAT-PG in sodium transport regulation mechanismPrincipal Investigator
- Principal Investigator
  
  ANZAI Naohiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
Organic solute transportsomes: their molecular assembly and functional significance
- Principal Investigator
  
  KANAI Yoshikatsu
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
  Kyorin University
Study on_the protein-protein interaction regulating the function of amino acid transporters
- Principal Investigator
  
  KANAI Yoshikatsu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
癌特異性アミノ酸トランスポーターLAT1発現を個性とする腫瘍の新規診断法の確立Principal Investigator
- Principal Investigator
  
  安西尚彦
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyorin University
腫瘍関連抗原4F2重鎖(CD98)のmTORを介するシグナル機構の解明
- Principal Investigator
  
  金井好克
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyorin University
Regulatory mechanism of urate transport function by urate transporter binding protein PDZK1Principal Investigator
- Principal Investigator
  
  ANZAI Naohiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Study of drug transport mechanism by renal organicion transporters and their clinical significance
- Principal Investigator
  
  HOSOYAMADA Makoto, 武田理夫
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
がん特異中性アミノ酸トランスポーター(LAT1)の発現と制御機序
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyorin University
Development of novel anti-uricosuric agents based on the genomic strategy.
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Identification and functional characterization of all the genes of heterodimeric amino acid transporter family by means of whole genome information
- Principal Investigator
  
  KANAI Yoshikatsu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyorin University
Genetic Abnormality of Renal Proximal Tubule-Specific Transporters as Causes of Sudden Death Syndrome in South-Eastern Asia
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
Identification of transporter genes regulating systemic kinetics of drugs and foreign compounds and their genetic polymorphism
- Principal Investigator
  
  ENDOU Hitoshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyorin University
REGULATION OF BODY WATER AND ELECTROLYTES CONCENTRATIONS BY RENAL NA/K/2CL TRANSPORTER (NKCC2)
- Principal Investigator
  
  KAWAHARA Katsumasa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  KITASATO UNIVERSITY
ラット腎髄質尿細管細胞における尿素輸送体の発現制御Principal Investigator
- Principal Investigator
  
  安西尚彦
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Kitasato University
ATP感受性K+チャネル(Kir6.1)とNa+/K+ポンプの機能的連関
- Principal Investigator
  
  河原克雅
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kitasato University
EXPRESSION OF Na^+-DEPENDENT GLUCOSE TRANSPORTERS (SGLT1, SGLT2) IN RAT KIDNEY PROXIMAL TUBULES.
- Principal Investigator
  
  KAWAHARA Katsumasa
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  KITASATO UNIVERSITY
腎尿細管ATP感受性K^+チャネルのホンプ,輸送体との機能的連関
- Principal Investigator
  
  KAWAHARA Katsumasa
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kitasato University

[Book] エース薬理学2020
- Author(s)
  金井好克、安西尚彦、安藤　仁、浅井　聰
- Total Pages
  303
- Publisher
  南山堂
- ISBN
  9784525140717
- Data Source
  KAKENHI-PROJECT-18K08200
[Book] 有機イオンと尿酸の輸送、臨床腎臓内科学2013
- Author(s)
  安西尚彦
- Data Source
  KAKENHI-PROJECT-23659447
[Book] 臨床腎臓内科学2013
- Author(s)
  安西尚彦
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-23659447
[Book] 青いおむつ症候群、別冊日本臨床新領域別症候群シリーズNo. 20先天性代謝異常症候群(第2版)2012
- Author(s)
  安西尚彦、岡本和久、堂前真理子
- Data Source
  KAKENHI-PROJECT-23659447
[Book] ハートナップ病、別冊日本臨床新領域別症候群シリーズNo. 20 先天性代謝異常症候群(第2版)2012
- Author(s)
  安西尚彦、花田健治、林啓太朗
- Data Source
  KAKENHI-PROJECT-23659447
[Book] 先天性代謝異常症候群（第2版）2012
- Author(s)
  安西尚彦
- Publisher
  株式会社　日本臨床社
- Data Source
  KAKENHI-PROJECT-23659447
[Book] Renal basis of hyperuricemia, In Gout and other crystal arthropathies(ed. Robert Terkertaub)2011
- Author(s)
  Anzai N, Endou H
- Publisher
  Elsevier, Philadelphia
- Data Source
  KAKENHI-PROJECT-21390073
[Book] 4 循環器薬理学 4.6 腎臓、実践臨床薬理学(中谷晴昭、大橋京一、越前宏俊編著)2010
- Author(s)
  安西尚彦
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-21390073
[Book] 薬物トランスポーター2009
- Author(s)
  安西尚彦
- Total Pages
  9
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21390073
[Book] 第3章3 2. URAT1 遺伝子変異と特発性腎性低尿酸血症、薬物トランスポーター最新ライブラリー(乾賢一編)2009
- Author(s)
  安西尚彦、三浦大作
- Publisher
  株式会社羊土社
- Data Source
  KAKENHI-PROJECT-21390073
[Book] 第1章8 27. SLC22A12(URAT1)、薬物トランスポーター最新ライブラリー(乾賢一編)2009
- Author(s)
  安西尚彦、福富俊之
- Publisher
  株式会社羊土社
- Data Source
  KAKENHI-PROJECT-21390073
[Book] 薬物トランスポーター2009
- Author(s)
  安西尚彦
- Total Pages
  9
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21659216
[Book] Drug transport in the kidney2007
- Author(s)
  Naohiko Anzai
- Total Pages
  30
- Publisher
  John Wiley & Sons, Inc.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Book] Annual Review 2004 腎臓2004
- Author(s)
  安西尚彦
- Total Pages
  7
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Book] Annual Review腎臓20042004
- Author(s)
  安西尚彦
- Total Pages
  6
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Book] Annual Review 2004 腎臓2004
- Author(s)
  安西尚彦
- Total Pages
  7
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-16023263
[Book] Annual Review腎臓20042004
- Author(s)
  安西尚彦
- Total Pages
  6
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] L-type amino acid transporter 1 as a target for inflammatory disease and cancer immunotherapy2022
- Author(s)
  Hayashi K, Anzai N.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 148 Issue: 1 Pages: 31-40
- DOI
  10.1016/j.jphs.2021.09.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03065, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K19348
[Journal Article] Contribution of LAT1-4F2hc in Urological Cancers via Toll-like Receptor and Other Vital Pathways2022
- Author(s)
  Zhao Xue、Sakamoto Shinichi、Maimaiti Maihulan、Anzai Naohiko、Ichikawa Tomohiko
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 1 Pages: 229-229
- DOI
  10.3390/cancers14010229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-21H03065, KAKENHI-PROJECT-21K19348
[Journal Article] Effects of 1,5-anhydro-D-glucitol on insulin secretion both in in vitro and ex vivo pancreatic preparations2022
- Author(s)
  Ouchi Motoshi、Morita Asuka、Satoh Keitaro、Kobayashi Shunsuke、Terada Misao、Kon Hiroe、Hayashi Keitaro、Suzuki Tatsuya、Oba Kenzo、Sugihara Hitoshi、Yasutake Masahiro、Anzai Naohiko、Fujita Tomoe
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 149 Issue: 2 Pages: 66-72
- DOI
  10.1016/j.jphs.2022.03.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11629
[Journal Article] Hypouricemia and Urate Transporters2022
- Author(s)
  Otani Naoyuki、Ouchi Motoshi、Misawa Kazuharu、Hisatome Ichiro、Anzai Naohiko
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 3 Pages: 652-652
- DOI
  10.3390/biomedicines10030652
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07316
[Journal Article] The Effects of Trypsin Inhibitor on Insulin Secretion Using Rat Pancreas in an Organ Bath2021
- Author(s)
  MORITA ASUKA、OUCHI MOTOSHI、SATOH KEITARO、KOBAYASHI SHUNSUKE、TERADA MISAO、WAKASHIN HIDEFUMI、KON HIROE、HAYASHI KEITARO、ANZAI NAOHIKO、SHIMIZU AKIRA、SUGIHARA HITOSHI、OBA KENZO、FUJITA TOMOE
- Journal Title
  
  In Vivo
  
  Volume: 35 Issue: 5 Pages: 2551-2558
- DOI
  10.21873/invivo.12537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-19K10051, KAKENHI-PROJECT-20K11629, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K15653
[Journal Article] Prognostic Value of High-Sensitivity Modified Glasgow Prognostic Score in Castration-Resistant Prostate Cancer Patients Who Received Docetaxel2021
- Author(s)
  Ando Keisuke、Sakamoto Shinichi、Saito Shinpei、Maimaiti Maihulan、Imamura Yusuke、Sazuka Tomokazu、Sato Nobuo、Komiya Akira、Anzai Naohiko、Ichikawa Tomohiko
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 4 Pages: 773-773
- DOI
  10.3390/cancers13040773
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-20K09555
[Journal Article] Functional analysis of LAT3 in prostate cancer: Its downstream target and relationship with androgen receptor2021
- Author(s)
  Rii Junryo、Sakamoto Shinichi、Sugiura Masahiro、Kanesaka Manato、Fujimoto Ayumu、Yamada Yasutaka、Maimaiti Maihulan、Ando Keisuke、Wakai Ken、Xu Minhui、Imamura Yusuke、Shindo Norihisa、Hirota Toru、Kaneda Atsushi、Kanai Yoshikatsu、Ikehara Yuzuru、Anzai Naohiko、Ichikawa Tomohiko
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 9 Pages: 3871-3883
- DOI
  10.1111/cas.14991
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07677, KAKENHI-PROJECT-19K07682, KAKENHI-PROJECT-20K21625, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-18H04034, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-21H03065, KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-20K18133, KAKENHI-PROJECT-21K20742
[Journal Article] Clinical Significance of <sup>18</sup>F-fluorodeoxyglucose and Glucose Transporter 1 mRNA in Clear Cell Renal Cell Carcinoma2021
- Author(s)
  BETSUNOH HIRONORI、SAKAMOTO SETSU、KAJI YASUSHI、NUKUI AKINORI、KOBAYASHI MINORU、YASHI MASAHIRO、HAYASHI KEITARO、ANZAI NAOHIKO、KAMAI TAKAO
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 10 Pages: 5179-5188
- DOI
  10.21873/anticanres.15336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-21H03065, KAKENHI-PROJECT-21K06581, KAKENHI-PROJECT-21K19348
[Journal Article] Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer2021
- Author(s)
  Sugiura Masahiro、Sato Hiroaki、Okabe Atsushi、Fukuyo Masaki、Mano Yasunobu、Shinohara Ken-ichi、Rahmutulla Bahityar、Higuchi Kosuke、Maimaiti Maihulan、Kanesaka Manato、Imamura Yusuke、Furihata Tomomi、Sakamoto Shinichi、Komiya Akira、Anzai Naohiko、Kanai Yoshikatsu、Luo Jun、Ichikawa Tomohiko、Kaneda Atsushi
- Journal Title
  
  Translational Oncology
  
  Volume: 14 Issue: 1 Pages: 100915-100915
- DOI
  10.1016/j.tranon.2020.100915
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-20K18133, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-18K16725, KAKENHI-PROJECT-19K16765, KAKENHI-PROJECT-20K09555
[Journal Article] The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-22021
- Author(s)
  Maimaiti Maihulan、Sakamoto Shinichi、Sugiura Masahiro、Kanesaka Manato、Fujimoto Ayumi、Matsusaka Keisuke、Xu Minhui、Ando Keisuke、Saito Shinpei、Wakai Ken、Imamura Yusuke、Nakayama Keiichi、Kanai Yoshikatsu、Kaneda Atsushi、Ikehara Yuzuru、Ikeda Jun-Ichiro、Anzai Naohiko、Ichikawa Tomohiko
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 11478-11478
- DOI
  10.1038/s41598-021-90748-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07457, KAKENHI-PROJECT-19K07682, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-20K09572, KAKENHI-PROJECT-21K06881, KAKENHI-PROJECT-20K18133, KAKENHI-PROJECT-21K20742
[Journal Article] まれな変異に重点を置いた尿酸値の遺伝率の研究2021
- Author(s)
  三澤計治、三島英換、長谷川嵩矩、大内基司、小島要、河合洋介、松尾雅文、安西尚彦、長﨑正朗
- Journal Title
  
  痛風と尿酸・核酸
  
  Volume: 45
- NAID
  130008067609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07316
[Journal Article] Expression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma.2020
- Author(s)
  Maimaiti M, Sakamoto S, Yamada Y, Sugiura M, Rii J, Takeuchi N, Imamura Y, Furihata T, Ando K, Higuchi K, Xu M, Sazuka T, Nakamura K, Kaneda A, Kanai Y, Kyprianou N, Ikehara Y, Anzai N, Ichikawa T.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1292-1292
- DOI
  10.1038/s41598-020-58136-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07682, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-17K11125, KAKENHI-PROJECT-18K19429, KAKENHI-PROJECT-20K09555
[Journal Article] Metabolic Acidosis Alters Expression of Slc22 Transporters in Mouse Kidney.2020
- Author(s)
  Gottier Nwafor J, Nowik M, Anzai N, Endou H, Wagner CA.
- Journal Title
  
  Kidney Blood Press Res
  
  Volume: 45 Issue: 2 Pages: 263-274
- DOI
  10.1159/000506052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08200
[Journal Article] Recent approaches to gout drug discovery: an update.2020
- Author(s)
  Otani N, Ouchi M, Kudo H, Tsuruoka S, Hisatome I, Anzai N.
- Journal Title
  
  Expert Opin Drug Discov.
  
  Volume: 15 Issue: 8 Pages: 943-954
- DOI
  10.1080/17460441.2020.1755251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08200
[Journal Article] Uric Acid Elevation by Favipiravir, an Antiviral Drug2020
- Author(s)
  Mishima Eikan、Anzai Naohiko、Miyazaki Mariko、Abe Takaaki
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 251 Issue: 2 Pages: 87-90
- DOI
  10.1620/tjem.251.87
- NAID
  130007853931
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-18K08200
[Journal Article] Evidence for Urate Uptake Through Monocarboxylate Transporter 9 Expressed in Mammalian Cells and Its Enhancement by Heat Shock2020
- Author(s)
  Otani Naoyuki、Kurata Yasutaka、Maharani Nani、Kuwabara Masanari、Ikeda Nobuhito、Notsu Tomomi、Li Peili、Miake Junichiro、Yoshida Akio、Sakaguchi Hiromi、Higaki Katsumi、Nakasone Naoe、Tsuneto Motokazu、Shirayoshi Yasuaki、Ouchi Motoshi、Ninomiya Haruaki、Yamamoto Kazuhiro、Anzai Naohiko、Hisatome Ichiro
- Journal Title
  
  Circulation Reports
  
  Volume: 2 Issue: 8 Pages: 425-432
- DOI
  10.1253/circrep.cr-20-0016
- NAID
  130007885744
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08557, KAKENHI-PROJECT-20K20662, KAKENHI-PROJECT-18K08200, KAKENHI-PROJECT-18K08074
[Journal Article] Contribution of Rare Variants of the SLC22A12 Gene to the Missing Heritability of Serum Urate Levels2020
- Author(s)
  Misawa Kazuharu、Hasegawa Takanori、Mishima Eikan、Jutabha Promsuk、Ouchi Motoshi、Kojima Kaname、Kawai Yosuke、Matsuo Masafumi、Anzai Naohiko、Nagasaki Masao
- Journal Title
  
  Genetics
  
  Volume: 214 Issue: 4 Pages: 1079-1090
- DOI
  10.1534/genetics.119.303006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08682, KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-18K08200
[Journal Article] Identification of the multivalent PDZ protein PDZK1 as a binding partner of sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8) and SMCT2 (SLC5A12).2019
- Author(s)
  Srivastava S, Nakagawa K, He X, Kimura T, Fukutomi T, Miyauchi S, Sakurai H, Anzai N.
- Journal Title
  
  J Physiol Sci
  
  Volume: 69 Issue: 2 Pages: 399-408
- DOI
  10.1007/s12576-018-00658-1
- NAID
  40021819085
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08200, KAKENHI-PROJECT-18K06608
[Journal Article] Sodium-coupled monocarboxylate transporter 1 interacts with the RING finger- and PDZ domain-containing protein PDZRN3.2019
- Author(s)
  Otsuka Y, Furihata T, Nakagawa K, Ohno Y, Reien Y, Ouchi M, Wakashin H, Tsuruoka S, Anzai N.
- Journal Title
  
  J Physiol Sci
  
  Volume: 69 Issue: 4 Pages: 635-642
- DOI
  10.1007/s12576-019-00681-w
- NAID
  40021916381
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08200
[Journal Article] Organic anion transporter OAT3 enhances the glucosuric effect of the SGLT2 inhibitor empagliflozin.2018
- Author(s)
  Fu Y, Breljak D, Onishi A, Batz F, Patel R, Huang W, Song P, Freeman B, Mayoux E, Koepsell H, Anzai N, Nigam SK, Sabolic I, Vallon V.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 315 Issue: 2 Pages: F386-F394
- DOI
  10.1152/ajprenal.00503.2017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08200
[Journal Article] Effects of uric acid on vascular endothelial function from bedside to bench2018
- Author(s)
  Otani Naoyuki、Toyoda Shigeru、Sakuma Masashi、Hayashi Keitaro、Ouchi Motoshi、Fujita Tomoe、Anzai Naohiko、Tanaka Atsushi、Node Koichi、Uemura Naoto、Inoue Teruo
- Journal Title
  
  Hypertension Research
  
  Volume: 41 Issue: 11 Pages: 923-931
- DOI
  10.1038/s41440-018-0095-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08603, KAKENHI-PROJECT-18K08200
[Journal Article] Cancer-Type OATP1B3 mRNA in Extracellular Vesicles as a Promising Candidate for a Serum-Based Colorectal Cancer Biomarker2018
- Author(s)
  Morio Hanae、Sun Yuchen、Harada Manami、Ide Hideyuki、Shimozato Osamu、Zhou Xujia、Higashi Kenjirou、Yuki Ryuzaburo、Yamaguchi Naoto、Hofbauer Josefina Pi??n、Guttmann-Gruber Christina、Anzai Naohiko、Akita Hidetaka、Chiba Kan、Furihata Tomomi
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 3 Pages: 445-449
- DOI
  10.1248/bpb.b17-00743
- NAID
  130006407493
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15985, KAKENHI-PROJECT-15K07922, KAKENHI-PROJECT-18K08200
[Journal Article] The uricosuric effects of dihydropyridine calcium channel blockers in vivo using urate under-excretion animal models.2018
- Author(s)
  Hori T, Ouchi M, Otani N, Nohara M, Morita A, Otsuka Y, Jutabha P, Shibasaki I, Matsushita Y, Fujita T, Fukuda H, Anzai N.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 136 Issue: 4 Pages: 196-202
- DOI
  10.1016/j.jphs.2017.11.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08200
[Journal Article] Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation.2018
- Author(s)
  Ohe T, Umezawa R, Kitagawara Y, Yasuda D, Takahashi K, Nakamura S, Abe A, Sekine S, Ito K, Okunushi K, Morio H, Furihata T, Anzai N, Mashino T.
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 28 Issue: 23-24 Pages: 3708-3711
- DOI
  10.1016/j.bmcl.2018.10.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08200, KAKENHI-PROJECT-16K08379
[Journal Article] Roles of organic anion transporters (OATs) in renal proximal tubules and their localization.2017
- Author(s)
  Otani N, Ouchi M, Hayashi K, Jutabha P, Anzai N.
- Journal Title
  
  Anat Sci Int
  
  Volume: 92 Issue: 2 Pages: 200-206
- DOI
  10.1007/s12565-016-0369-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461258
[Journal Article] Molecular mechanism of the urate-lowering effects of calcium channel blockers2016
- Author(s)
  Fukuda H, Anzai N, et al.
- Journal Title
  
  Dokkyo J Med Sci
  
  Volume: 43 Pages: 23-29
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670600
[Journal Article] Molecular mechanism of the irate-lowering effects of calcium channel blockers.2016
- Author(s)
  Tsuchiya G, Hori T, Onizawa N, Omani N, Tanaka-Nakadate S, Iseki T, Ouchi M, Hayashi K, Jutabha P, Oba T, Fukuda H, Anzai N.
- Journal Title
  
  Dokkyo J Med Sci.
  
  Volume: 43 Pages: 23-29
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461258
[Journal Article] Molecular mechanism of urate-lowering effects of anserine nitrate2016
- Author(s)
  Otsuka Y, Ohno Y, Morita A, Otani N, Jutabha P, Ouchi M, Tsuruoka S, Anzai N
- Journal Title
  
  Gout Nucleic Acid Metabol
  
  Volume: 40 Pages: 137-143
- NAID
  130005251395
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461258
[Journal Article] Distribution of organic anion transporters NaDC3 and OAT1-3 along the human nephron.2016
- Author(s)
  Breljak D, Ljubojevic M, Hagos Y, Micek V, Balen Eror D, Vrhovac Madunic I, Brzica H, Karaica D, Radovic N, Kraus O, Anzai N, Koepsell H, Burckhardt G, Burckhardt BC, Sabolic I.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 311 Issue: 1 Pages: F227-F238
- DOI
  10.1152/ajprenal.00113.2016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461258
[Journal Article] 4.Kokura K, Kuromi Y, Endo T, Anzai N, Kazuki Y, Oshimura M, Ohbayashi T.2016
- Author(s)
  Kokura K, Kuromi Y, Endo T, Anzai N, Kazuki Y, Oshimura M, Ohbayashi T.
- Journal Title
  
  J Gene Med.
  
  Volume: 18 Issue: 10 Pages: 273-281
- DOI
  10.1002/jgm.2925
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-26461258, KAKENHI-PROJECT-16K08548
[Journal Article] Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents.2016
- Author(s)
  Mishima M, Anzai N, et al.
- Journal Title
  
  Drug Res
  
  Volume: 66 Issue: 05 Pages: 270-274
- DOI
  10.1055/s-0035-1569405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670600, KAKENHI-PROJECT-25461057, KAKENHI-PROJECT-26461258
[Journal Article] Expression of basolateral organic anion and cation transporters in experimental cadmium nephrotoxicity in rat kidney.2016
- Author(s)
  Ljubojevic M, Breljak D, Herak-Kramberger CM, Anzai N, Sabolic I.
- Journal Title
  
  Arch Toxicol.
  
  Volume: 90 Issue: 3 Pages: 525-541
- DOI
  10.1007/s00204-015-1450-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461258, KAKENHI-PROJECT-25670600
[Journal Article] Interaction of green tea catechins with renal organic cation transporter 2.2015
- Author(s)
  Jaiyen C, Jutabha P, Anzai N, Lungkaphin A, Soodvilai S, Srimaroeng C.
- Journal Title
  
  Xenobiotica
  
  Volume: 17 Pages: 1-10
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461258
[Journal Article] Organic Anion Transporter 5 (Oat5) Urinary Excretion Is a Specific Biomarker of Kidney Injury: Evaluation of Urinary Excretion of Exosomal Oat5 after N-Acetylcysteine Prevention of Cisplatin Induced Nephrotoxicity.2015
- Author(s)
  Bulacio RP, Anzai N, Ouchi M, Torres AM.
- Journal Title
  
  Chem Res Toxicol.
  
  Volume: 28 Issue: 8 Pages: 1595-1602
- DOI
  10.1021/acs.chemrestox.5b00176
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461258
[Journal Article] LAT1 is a central transporter of essential amino acids in human umbilical vein endothelial cells.2014
- Author(s)
  Hayashi K, Jutabha P, Kamai T, Endou H, Anzai N
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 124 Pages: 511-513
- NAID
  130003391512
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590647
[Journal Article] LAT1 is a central transporter of essential amino acids in human umbilical vein endothelial cells.2014
- Author(s)
  Hayashi K, Jutabha P, Kamai T, Endou H, Anzai N
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 124 Pages: 511-513
- NAID
  130003391512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461258
[Journal Article] LAT1 is a central transporter of essential amino acids in human umbilical vein endothelial cells.2014
- Author(s)
  Hayashi K, Jutabha P, Kamai T, Endou H, Anzai N
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 124 Pages: 511-513
- NAID
  130003391512
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670600
[Journal Article] Role of LAT1 in promotion of amino acid incorporation in activated T cells.2014
- Author(s)
  Hayashi K, Anzai N
- Journal Title
  
  Crit Rev Immunol.
  
  Volume: 34 Pages: 467-479
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590328
[Journal Article] Role of LAT1 in the promotion of amino acid incorporation in activated T cells.2014
- Author(s)
  Hayashi K, Anzai N
- Journal Title
  
  Crit Rev Immunol
  
  Volume: 34 Pages: 467-479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461258
[Journal Article] LAT1 is a central transporter of essential amino acids in human umbilical vein endothelial cell.2014
- Author(s)
  Hayashi K, Jutabha P, Kamai T, Endou H, Anzai N
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 124 Pages: 511-513
- NAID
  130003391512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590328
[Journal Article] Evidence for tachykinin NK3 receptors-triggered peptide YY release from isolated guinea-pig distal colon.2014
- Author(s)
  Kojima S, Tohei A, Kojima K, Anzai N
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 740 Pages: 121-126
- DOI
  10.1016/j.ejphar.2014.06.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461258
[Journal Article] Organic solute transporters and diseases: potential therapeutic targets.2013
- Author(s)
  Anzai N
- Journal Title
  
  Curr Mol Pharmacol
  
  Volume: 6 Pages: 65-65
- Data Source
  KAKENHI-PROJECT-25670600
[Journal Article] LAT1 is a critical transporter of essential amino acids for immune reactions in activated human T cells.2013
- Author(s)
  Hayashi K, Jutabha P, et al
- Journal Title
  
  J Immunol.
  
  Volume: 191 Issue: 8 Pages: 4080-4085
- DOI
  10.4049/jimmunol.1300923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590647, KAKENHI-PROJECT-24590328, KAKENHI-PROJECT-25670600
[Journal Article] Sex-dependent expression of Oat3 (Slc22a8) and Oat1 (Slc22a6) proteins in murine kidneys.2013
- Author(s)
  Breljak D, Brzica H, Sweet DH, Anzai N, Sabolic I.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 304巻 Issue: 8 Pages: 1114-1126
- DOI
  10.1152/ajprenal.00201.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659447
[Journal Article] Functional cooperation of URAT1 (SLC22A12) and URATv1 (SLC2A9) in renal reabsorption of urate2013
- Author(s)
  Nakanishi T, Ohya K, Shimada S, Anzai N, Tamai I
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 28巻 Issue: 3 Pages: 603-611
- DOI
  10.1093/ndt/gfs574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659447, KAKENHI-PROJECT-24890073
[Journal Article] Mitochondrial metabolism in the noncancerous liver determine the occurrence of hepatocellular carcinoma: a prospective study.2013
- Author(s)
  Kudo A, Mogushi K, Takayama T, Matsumura S, Ban D, Irie T, Ochiai T, Nakamura N, Tanaka H, Anzai N, Sakamoto M, Tanaka S, Arii S
- Journal Title
  
  J Gastroenterol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659447
[Journal Article] Organic cation transporter 2 (SLC22A2), a low-affinity and high-capacity choline transporter, is preferentially enriched on synaptic vesicles in cholinergic neurons.2013
- Author(s)
  Nakata T, Anzai N, et al.
- Journal Title
  
  Neuroscience
  
  Volume: 252 Pages: 212-221
- DOI
  10.1016/j.neuroscience.2013.08.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670600, KAKENHI-PROJECT-25860152
[Journal Article] Recent advances in renal urate transport : characterization of candidate transporters indicated by genome-wide association studies2012
- Author(s)
  Anzai N, Jutabha P, Amonpatumrat -Takahashi S, Sakurai H
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 16 Issue: 1 Pages: 89-95
- DOI
  10.1007/s10157-011-0532-z
- NAID
  10030342927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] オーバービュー : 疾患発症の基本ユニットとしてのトランスポートソーム2012
- Author(s)
  安西尚彦
- Journal Title
  
  日薬理誌
  
  Volume: 139 Pages: 52-55
- NAID
  10030456120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells.2012
- Author(s)
  Hayashi K, Jutabha P, et al.
- Journal Title
  
  Oncol Rep
  
  Volume: 28 Issue: 3 Pages: 862-866
- DOI
  10.3892/or.2012.1878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590647, KAKENHI-PROJECT-23659447
[Journal Article] A role for endogenous peptide YY in tachykinin NK(2) receptor-triggered 5-HT release from guinea pig isolated colonic mucosa2012
- Author(s)
  Kojima S, Tohei A, Anzai N
- Journal Title
  
  Br J Pharmacol
  
  Volume: 167 Issue: 6 Pages: 1362-1368
- DOI
  10.1111/j.1476-5381.2012.02094.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073, KAKENHI-PROJECT-23659447
[Journal Article] The involvement of L-type amino acid transporters in theanine transport2012
- Author(s)
  Yamamoto S, Kimura T, Tachiki T, Anzai N, Sakurai T, Ushimaru M
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 76巻 Pages: 2230-2235
- NAID
  10031146837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659447
[Journal Article] Recent advances in renal urate transport : characterization of candidate transporters indicated by genome-wide association studies2012
- Author(s)
  Anzai N, et al
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: Vol.16 Pages: 89-95
- NAID
  10030342927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Potent human uric acid transporter 1 inhibitors : in vitro and in vivo metabolism and pharmacokinetic studies2012
- Author(s)
  Wempe MF, Lightner JW, Miller B, Iwen TJ, Rice PJ, Wakui S, Anzai N, Jutabha P, Endou H
- Journal Title
  
  Drug Des Devel Ther
  
  Volume: 6 Pages: 323-339
- DOI
  10.2147/dddt.s35805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073, KAKENHI-PROJECT-23590647
[Journal Article] A role for the organic anion transporter OAT3 in renal creatinine secretion in mice.2012
- Author(s)
  Vallon V, Eraly SA, Rao SR, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 302巻 Issue: 10 Pages: 1293-1299
- DOI
  10.1152/ajprenal.00013.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659447
[Journal Article] c-Myc is crucial for the expression of LAT1 in MIA Paca-2 human pancreatic cancer cells.2012
- Author(s)
  Hayashi, K., Jutabha, P., Endou, H., Anzai, N.
- Journal Title
  
  Oncol. Rep.
  
  Volume: 28 Pages: 537-544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590328
[Journal Article] Developing potent human uric acid transporter 1 (hURAT1) inhibitors2011
- Author(s)
  Wempe MW, Anzai N, et al
- Journal Title
  
  J Med Chem
  
  Volume: Vol.54 Pages: 2701-2713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Urate transporters : an evolving field2011
- Author(s)
  Anzai N, Endou H
- Journal Title
  
  Semin Nephrol
  
  Volume: 31 Issue: 5 Pages: 400-409
- DOI
  10.1016/j.semnephrol.2011.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] 尿酸降下薬の分子標的としての腎尿酸トランスポートソーム2011
- Author(s)
  安西尚彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 236 Pages: 863-864
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Increased expression of SLC2A9 decreases urate excretion from the kidney2011
- Author(s)
  Kimura T, Anzai N, et al
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: Vol.30 Pages: 1295-1301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Clinical and functional characterization of URAT1 variants2011
- Author(s)
  Tasic V, Hynes AM, Kitamura K, Cheong HI, Lozanovski VJ, Gucev Z, Jutabha P, Anzai N, Sayer JA
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 12 Pages: e28641-e28641
- DOI
  10.1371/journal.pone.0028641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073, KAKENHI-PROJECT-21591035
[Journal Article] Developing potent human uric acid transporter 1 (hURAT1) inhibitors2011
- Author(s)
  Wempe MF, Jutabha P, Quade B, Iwen TJ, Frick MM, Ross IR, Rice PJ, Anzai N, Endou H
- Journal Title
  
  J Med Chem
  
  Volume: 54 Issue: 8 Pages: 2701-2713
- DOI
  10.1021/jm1015022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] 高尿酸血症のモデル動物2011
- Author(s)
  安西尚彦、内田幸介、林啓太朗
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 33 Pages: 462-467
- NAID
  40019154794
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Human urate transporter 1 (hURAT1) mediates the transport of orotate2011
- Author(s)
  Miura D, Anzai N, Jutabha P, Chanluang S, He X, Fukutomi T, Endou H
- Journal Title
  
  J Physiol Sci
  
  Volume: 61 Issue: 3 Pages: 253-257
- DOI
  10.1007/s12576-011-0136-0
- NAID
  10029050258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073, KAKENHI-PROJECT-23659447, KAKENHI-PROJECT-23790952
[Journal Article] Increased expression of SLC2A9 decreases urate excretion from the kidney2011
- Author(s)
  Kimura T, Amonpatumrat S, Tsukada A, Fukutomi T, Jutabha P, Thammapratip T, Lee EJ, Ichida K, Anzai N, Sakurai H
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 30 Issue: 12 Pages: 1295-1301
- DOI
  10.1080/15257770.2011.628354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073, KAKENHI-PROJECT-23790952
[Journal Article] 尿酸排泄促進薬2011
- Author(s)
  安西尚彦、内田幸介、堂前真理子
- Journal Title
  
  尿酸産生抑制薬の種々の尿酸トランスポーターへの作用、高尿酸血症と痛風
  
  Volume: 19 Pages: 121-125
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Apical voltage-driven urate efflux transporter NPT4 in renal proximal tubule2011
- Author(s)
  Jutabha P, Anzai N, Wempe MF, Wakui S, Endou H, Sakurai H
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids
  
  Volume: 30 Issue: 12 Pages: 1302-1311
- DOI
  10.1080/15257770.2011.616564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073, KAKENHI-PROJECT-23659447
[Journal Article] A novel human organic anion transporter NPT4 mediates the transport of ochratoxin A.2011
- Author(s)
  Jutabha P, Anzai N, et al.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 116 Pages: 392-396
- NAID
  10029895719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659447
[Journal Article] Clinical and functional characterization of URAT1 variants2011
- Author(s)
  Tasic V, Anzai N, et al
- Journal Title
  
  PLoS One
  
  Volume: Vol.6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] A novel human organic anion transporter NPT4 mediates the transport of ochratoxin A2011
- Author(s)
  Jutabha P, Anzai N, Hayashi K, Domae M, Uchida K, Endou H, Sakurai H
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 116 Pages: 392-396
- NAID
  10029895719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659447
[Journal Article] Functional Analysis of Human Sodium-Phosphate Transporter 4 (NPT4/SLC17A3) Polymorphisms.2011
- Author(s)
  Jutabha P, Anzai N, Kimura T, Taniguchi A, Urano W, Yamanaka H, Endou H, Sakurai H.
- Journal Title
  
  J Pharmacol Sci. 115
  
  Pages: 249-253
- NAID
  10029892290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790819
[Journal Article] Human urate transporter 1 (hURAT1) mediates the transport of orotate.2011
- Author(s)
  Miura D, Anzai N, et al.
- Journal Title
  
  J Physiol Sci.
  
  Volume: 61 Pages: 253-257
- NAID
  10029050258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659447
[Journal Article] 新規ヒト有機酸排出トランスポーターhNPT4 (SLC17A3) の輸送特性2011
- Author(s)
  安西尚彦、Jutabha Promsuk、木村徹、遠藤仁、櫻井裕之
- Journal Title
  
  痛風と核酸代謝
  
  Volume: 35 Pages: 31-37
- NAID
  10029325947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Interactions of urate transporter URAT1 in human kidney with uricosuric drugs2011
- Author(s)
  Shin HJ, Takeda M, Enomoto A, Fujimura M, Miyazaki H, Anzai N, Endou H
- Journal Title
  
  Nephrology (Carlton)
  
  Volume: 16 Issue: 2 Pages: 156-162
- DOI
  10.1111/j.1440-1797.2010.01368.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Urate transporters : an evolving field2011
- Author(s)
  Anzai N
- Journal Title
  
  Semin Nephrol
  
  Volume: Vol.31 Pages: 400-409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Apical voltage-driven urate efflux transporter NPT4 in renal proximal tubule.2011
- Author(s)
  Jutabha P, Anzai N, et al.
- Journal Title
  
  Nucleosides Nucleotides Nucleic Acids.
  
  Volume: 30 Pages: 1302-1311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659447
[Journal Article] Concentration-dependent inhibitory effect of irbesartan on renal uric acid transporters2010
- Author(s)
  Nakamura M, Anzai N, Jutabha P, et al
- Journal Title
  
  J Pharmacol Sci 114
  
  Pages: 115-8
- NAID
  10029890030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590965
[Journal Article] Human sodium-phosphate transporter 4 (hNpT4/SLC17A3) as a commonrenal secretory pathway for drugs and urate.2010
- Author(s)
  Jutabha P, Anzai N, Kitamura K, Taniguchi A, Kaneko S, Yan K, Yamada H, Shimada H, Kimura T, et al.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285 Pages: 35123-35132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790819
[Journal Article] Functional Analysis of Human Organic Cation Transporter OCT3 (SLC22A3) Polymorphisms.2010
- Author(s)
  Sakata T, Anzai N, Kimura T, et al.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 113 Pages: 263-266
- NAID
  10029889401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790819
[Journal Article] Sodium-dependent phosphate cotransporter type 1 sequence polymorphisms in male patients with gout2010
- Author(s)
  Urano W, Taniguchi A, Anzai N, Inoue E, Kanai Y, Yamanaka M, Endou H, Kamatani N, Yamanaka H
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 69 Issue: 6 Pages: 1232-1234
- DOI
  10.1136/ard.2008.106856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Association between GLUT9 and gout in Japanese men2010
- Author(s)
  Urano W, Taniguchi A, Anzai N, Inoue E, Sekita C, Endou H, Kamatani N, Yamanaka H
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 69 Issue: 5 Pages: 932-923
- DOI
  10.1136/ard.2009.111096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] 全ゲノム関連解析がひも解く痛風発症因子としての尿酸トランスポーター2010
- Author(s)
  安西尚彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 233 Pages: 498-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Identification of a novel organic anion transporter mediating carnitine transport in mouse liver and kidney2010
- Author(s)
  Tsuchida H, Anzai N, Shin HJ, Wempe MF, Jutabha P, Enomoto A, Cha SH, Satoh T, Ishida M, Sakurai H, Endou H
- Journal Title
  
  Cell Physiol Biochem
  
  Volume: 25 Issue: 4-5 Pages: 511-522
- DOI
  10.1159/000303060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Human sodium-phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate.2010
- Author(s)
  Jutabha P, Anzai N, Kitamura K, Taniguchi A, Kaneko S, Yan K, Yamada H, Shimada H, Kimura T, Katada T, Fukutomi T, Tomita K, Urano W, Yamanaka H, Seki G, Fujita T, Moriyama Y, Yamada A, Uchida S, Wempe MF, Endou H, Sakurai H.
- Journal Title
  
  J Biol Chem. 285
  
  Pages: 35123-35132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790819
[Journal Article] L-type amino acid transporter 1 inhibitors inhibit tumor cell growth.2010
- Author(s)
  Oda K, Hosoda N, Endo H, Saito K, Tsujihara K, Yamamura M, Sakata T, Anzai N, Wempe MF, Kanai Y, Endou H.
- Journal Title
  
  Cancer Sci. 101
  
  Pages: 173-179
- NAID
  10027200053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] A novel transporter of SLC22 family specifically transports prostaglandins and colocalizes with 15- PGDH in renal proximal tubules2010
- Author(s)
  Shiraya K, Hirata T, Hatano R, Nagamori S, Wiriyasermkul P, Jutabha P, Matsubara M, Muto S, Tanaka H, Asano S, Anzai N, Endou H, Yamada A, Sakurai H, Kanai Y
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Issue: 29 Pages: 22141-22151
- DOI
  10.1074/jbc.m109.084426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] A novel transporter of SLC22 family specifically transports prostaglandins and co-localizes with 15-hydroxyprostaglandin dehydrogenase in renal proximal tubules.2010
- Author(s)
  Shiraya K, Hirata T, Hatano R, Nagamori S, Wiriyasermkul P, Jutabha P, Matsubara M, Muto S, Tanaka H, Asano S, Anzai N, Endou H, Yamada A, Sakurai H, Kanai Y
- Journal Title
  
  J Biol Chem. 285
  
  Pages: 22141-22151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Type 1 sodium dependent phosphate transporter (SLC17A1 protein) is a Cl^- -dependent urate exporter2010
- Author(s)
  Iharada, M., Miyaji, T., Fujimoto, T., Hiasa,M., Anzai, N., Omote, H., and Moriyama, Y
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Issue: 34 Pages: 26107-26113
- DOI
  10.1074/jbc.m110.122721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370057, KAKENHI-PROJECT-21390073
[Journal Article] ヒト尿酸トランスポーターURAT1 によるサリチル酸輸送2010
- Author(s)
  大津尚子、安西尚彦、福冨俊之、木村徹、櫻井裕之、遠藤仁
- Journal Title
  
  日腎会誌
  
  Volume: 52 Pages: 499-504
- NAID
  10026409305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Concentration-dependent inhibitory effect of irbesartan on renal uric acid transporters2010
- Author(s)
  Nakamura M, Anzai N, Jutabha P, Sato H, Sakurai H, Ichida K
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 114 Pages: 115-118
- NAID
  10029890030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] 尿酸トランスポーターURAT1トランスジェニックマウスにおける尿酸の体内動態2010
- Author(s)
  塚田愛、木村徹、Promsuk Jutabha、安西尚彦、市田公美、櫻井裕之
- Journal Title
  
  痛風と核酸代謝 34
  
  Pages: 171-178
- NAID
  10027722204
- Data Source
  KAKENHI-PROJECT-21790819
[Journal Article] Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate2010
- Author(s)
  Jutabha P, Anzai N, Kitamura K, Taniguchi A, Kaneko S, Yan K, Yamada H, Shimada H, Kimura T, Katada T, Fukutomi T, Tomita K, Urano W, Yamanaka H, Seki G, Fujita T, Moriyama Y, Yamada A, Uchida S, Wempe MF, Endou H, Sakurai H
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Issue: 45 Pages: 35123-35132
- DOI
  10.1074/jbc.m110.121301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human2010
- Author(s)
  Sato M, Mamada H, Anzai N, Shirasaka Y, Nakanishi T, Tamai I
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 33 Pages: 498-503
- NAID
  130000248105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] 腎臓尿酸輸送の分子機序 : 新規創薬標的としての尿酸トランスポーター、特集高尿酸血症・痛風治療のブレイクスルー2010
- Author(s)
  安西尚彦
- Journal Title
  
  日薬理誌
  
  Volume: 136 Pages: 316-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390073
[Journal Article] regulates the cellular localization and function of ABCB4.2009
- Author(s)
  Ikebuchi Y, Takada T, Ito K, Yoshikado T, Anzai N, Kanai Y, Suzuki H.
- Journal Title
  
  Hepatol Res. 39
  
  Pages: 1091-1097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Receptor for activated C-kinase 1 regulates the cellular localization and function of ABCB4.2009
- Author(s)
  Ikebuchi Y, Takada T, Ito K, Yoshikado T, Anzai N, et al.
- Journal Title
  
  Hepatol Res. 39
  
  Pages: 1091-1107
- NAID
  10027405617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Sodium-dependent phosphate cotransporter type 1 (NPT1) sequence polymorphisms in male patients with gout.2009
- Author(s)
  Urano W, Taniguchi A, Anzai N, Inoue E, Kanai Y, Yamanaka M, Kamatani N, Endou H, Yamanaka H.
- Journal Title
  
  Ann Rheum Dis.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] 新規尿酸排出トランスポーターURATv1の尿酸輸送特性の解析2009
- Author(s)
  木村徹、安西尚彦、Promsuk Jutabha、三浦大作、遠藤仁、櫻井裕之
- Journal Title
  
  痛風と核酸代謝 33
  
  Pages: 177-182
- NAID
  10025596953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790819
[Journal Article] Posttranslational regulation of Abcc2 expression by SUMOylation system2009
- Author(s)
  Minami S, Ito K, Honma M, Ikebuchi Y, Anzai Y, et.al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 296
  
  Pages: 406-413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] 腎臓の尿酸トランスポーター:最近の進歩2009
- Author(s)
  安西尚彦、Promsuk Jutabha、木村徹、櫻井裕之
- Journal Title
  
  痛風と核酸代謝 33
  
  Pages: 7-15
- NAID
  10025596817
- Data Source
  KAKENHI-PROJECT-21790819
[Journal Article] 腎臓の尿酸トランスポーター:最近の進歩2009
- Author(s)
  安西尚彦
- Journal Title
  
  痛風と核酸代謝 33
  
  Pages: 7-15
- NAID
  10025596817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659216
[Journal Article] 新規尿酸排出トランスポータ-URArv1の尿酸輸送特性の解析2009
- Author(s)
  木村徹、安西尚彦、Promsuk Jutabha、三浦大作、遠藤仁、櫻井裕之
- Journal Title
  
  痛風と核酸代謝 33
  
  Pages: 177-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790819
[Journal Article] Plasma urate level is directly regulated by a voltage-driven urate efflux transporter uratvl (slc2a9) in humans.2008
- Author(s)
  Anzai N. Ichida K, Jutabha P, Kimura T, Babu E, Jin CJ, Srivastava S, Kitamura K, Hisatome I, Endou H, Sakurai H.
- Journal Title
  
  J Biol Chem. 283
  
  Pages: 26834-26838
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] Plasma Urate Level Is Directly Regulated by a Voltage-Driven Urate Efflux Transporter URATvl(SLC2A9) in Humans.2008
- Author(s)
  N. Anzai
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 26834-26838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590965
[Journal Article] Functional and immunochemical characterization of a novel organic anion transporter Oat8(Slc22a9)in rat renal collecting duct2008
- Author(s)
  Yokoyama. Anzai N, Ljubojevic M, Ohtsu N, Sakata T, et.al.
- Journal Title
  
  Cell Physiol Biochem. 21
  
  Pages: 269-278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] 膜輸送蛋白質Up-to-Date2008
- Author(s)
  安西尚彦
- Journal Title
  
  日本腎臓学会誌 50
  
  Pages: 110-113
- NAID
  10024900277
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans2008
- Author(s)
  Anzai N, Ichida K, Jutabha P, et al
- Journal Title
  
  J Biol Chem 283
  
  Pages: 26834-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590965
[Journal Article] Functional and immunochemical characterization of a novel organic anion transporter Oat8 (Slc22a9) in rat renal collecting duct.2008
- Author(s)
  Yokoyama H, Anzai N. Ljubojevic M, Ohtsu N, Sakata T, Miyazaki H, Nonoguchi H, Islam R, Onozato M, Tojo A, Tomita K, Kanai Y, Igarashi T, Sabolic I, Endou H.
- Journal Title
  
  Cell Physiol Biochem. 21
  
  Pages: 269-278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans2008
- Author(s)
  Anzai N
- Journal Title
  
  J Biol Chem 283
  
  Pages: 26834-26838
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] New insights into renal transport of urate.2007
- Author(s)
  Anzai N. Kanai Y, Endou H.
- Journal Title
  
  Curr Opin Rheumatol. 19
  
  Pages: 151-157
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] New Insights into Renal Transport of Urate.2007
- Author(s)
  Anzai N, et al.
- Journal Title
  
  Curr Opin Rheumatol. 19
  
  Pages: 151-157
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] New Insights into Renal Transport of Urate.2007
- Author(s)
  Anzai N, et al.
- Journal Title
  
  Curr Opin Rheumatol. 19
  
  Pages: 151-157
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Renal expression of organic anion transporter OAT2 in rats and mice is regulated by sex hormones.Am J Physiol Renal Physiol.292:F361-F372,20072007
- Author(s)
  Ljubojevic M, Balen D, Breljak D, Kusan M, Anzai A N, Bahn A, Burckhardt G, Sabolic I.
- Journal Title
  
  Am JPhysiol Renal Physiol 292
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] New Insights into Renal Transport of Urate2007
- Author(s)
  Anzai N, Kanai Y, Endou H.
- Journal Title
  
  Curr Opin Rheumatol 19
  
  Pages: 151-157
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate.2007
- Author(s)
  Shin HJ, Anzai N, Enomoto A, He X, Kim do K, Endou H, Kanai Y.
- Journal Title
  
  Hepatology.
  
  Pages: 1046-1055
- NAID
  130005449292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] New insights into renal transport of urate.2007
- Author(s)
  Anzai N
- Journal Title
  
  Curr Opin Rheumatol 19
  
  Pages: 151-157
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate.2007
- Author(s)
  Shin, HJ・Anzai, N・Enomoto, A・He, X・Kim do, K・Endou, et. al.
- Journal Title
  
  Hepatology 45
  
  Pages: 1046-1055
- NAID
  130005449292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport.2007
- Author(s)
  Cunningham R, Brazie M, Kanumuru S, E X, Biswas R, Wang F, Steplock D, Wade JB, Anzai N. Endou H, Shenolikar S, Weinman EJ.
- Journal Title
  
  J Am Soc Nephrol. 18
  
  Pages: 1419-1425
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] Renal expression of organic anion transporter OAT2 in rats and mice is regulated by sex hormones.2007
- Author(s)
  Ljubojevic, M・Balen, D・Brrljak, D・Kusan, K・Anzai, N, et. al.
- Journal Title
  
  Am J Physiol Renal Physiol. 292
  
  Pages: 361-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] New insights into renal transport of urate.2007
- Author(s)
  Anzai N
- Journal Title
  
  Curr Opin Rheumatol. 19・2
  
  Pages: 151-157
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate.2007
- Author(s)
  Shin HJ, Anzai N, Enomoto A, He X, Kim do K, Endou H, Kanai Y.
- Journal Title
  
  Hepatology. 45
  
  Pages: 1046-1055
- NAID
  130005449292
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] Role of mouse organic anion transporter 3 (m0at3) as a basolateral prostaglandin E2 transport pathway.2007
- Author(s)
  Nilwarangkoon S, Anzai N. Shiraya K, Yu E, Islam R, Cha SH, Onozato ML, Miura D, Jutabha P, Tojo A, Kanai Y, Endou H.
- Journal Title
  
  J Pharmacol Sci. 103
  
  Pages: 48-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] Organic anion transporter family : current knowledge.2006
- Author(s)
  Anzai N, et al.
- Journal Title
  
  Pharmacol Sci. 100
  
  Pages: 411-426
- NAID
  10018238661
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Organic anion transporter family : current knowledge2006
- Author(s)
  Anzai N, Kanai Y, Endou H.
- Journal Title
  
  J Pharmacol Sci. 100
  
  Pages: 411-426
- NAID
  10018238661
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] Organic anion transporter family : current knowledge2006
- Author(s)
  Anzai, N, Kanai, Y, Endou, H
- Journal Title
  
  J Am Soc Nephrol 17
  
  Pages: 1791-1795
- NAID
  10018238661
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] Expression of rat renal cortical OAT1 and OAT3 in response to acute iliary obstruction2006
- Author(s)
  Brandoni A, Villar SR, Picena JC, Anzai N, Endou H, Tones AM
- Journal Title
  
  Hepatology 43
  
  Pages: 1092-1100
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter.2006
- Author(s)
  Shigeta Y, Kanai Y, Chairoungdua A, Ahmed N, Sakamoto S, Matsuo H, Kim DK, Fujimura M, Anzai N, Mizoguchi K, Ueda T, Akakura K, Ichikawa T, Ito H, Endou H.
- Journal Title
  
  Kidney Int. 69(7)
  
  Pages: 1198-1206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Identification and characterization of a novel renal prostaglandin-specific organic anion transporter (OAT-PG) structurally distinct from PGT.2006
- Author(s)
  Anzai N, Shiraya K, Hirata T, Jutabha P, Hatano R, Sanada S, Matsubara M, MutoS, Endou H, Lanai Y.
- Journal Title
  
  J Pharmacol Sci. 100
  
  Pages: 111-111
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] Expression of rat renal cortical OAT1 and OAT3 in response to acute biliary obstruction2006
- Author(s)
  Brandoni, A, Villar, SR, Picena, JC, Anzai, N, Endou, H, Torres, AM
- Journal Title
  
  Hepatology 43
  
  Pages: 1092-1100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter.2006
- Author(s)
  Shigeta Y, Kanai Y, Chairoungdua A, Ahmed N, Sakamoto S, Matsuo H, Kim DK, Fujimura M, Anzai N, Mizoguchi K, Ueda T, Akakura K, Ichikawa T, Ito H, Endou H.
- Journal Title
  
  Kidney Int.
  
  Pages: 1198-1206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity2006
- Author(s)
  Noshiro, R, Anzai, N, Sakata, T, Miyazaki, H, Terada, T, Shin, HJ, He, X, Miura, D, Inui, K, Kanai, Y, Endou, H
- Journal Title
  
  Kidney Int 70
  
  Pages: 275-282
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] Organic anion transporter family : current knowledge.2006
- Author(s)
  Anzai N
- Journal Title
  
  J Pharmacol Sci. 100・5
  
  Pages: 411-426
- NAID
  10018238661
- Data Source
  KAKENHI-PROJECT-18590900
[Journal Article] A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter2006
- Author(s)
  Shigeta, Y, Kanai, Y, Chairoungdua, A, Ahmed, N, Sakamoto, S, Matsuo, H, Kim, DK, Fujimura, M, Anzai, N, Mizoguchi, K, Ueda, T, Akakura, K, Ichikawa, T, Ito, H, Endou, H
- Journal Title
  
  Kidney Int 69
  
  Pages: 1198-1206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] 腎尿酸トランスポーターと血清尿酸値異常2006
- Author(s)
  安西尚彦, 他
- Journal Title
  
  医学のあゆみ 216
  
  Pages: 685-691
- NAID
  130005024538
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Organic anion transporter family : current knowledge.2006
- Author(s)
  Anzai N, et al.
- Journal Title
  
  Pharmacol Sci. 100
  
  Pages: 411-426
- NAID
  10018238661
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] セファロリジン投与ヒト有機アニオントランスポーター1安定発現近位尿細管細胞(S2-hOAT1)における網羅的遺伝子発現解析2006
- Author(s)
  安西尚彦, 他
- Journal Title
  
  腎とフリーラジカル 8
  
  Pages: 67-69
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] A novel missense mutation of SLC7A9 frequent in Japanese cystinuria cases affecting the C-terminus of the transporter.2006
- Author(s)
  Shigeta Y, Kanai Y, Chairoungdua A, Ahmed N, Sakamoto S, Matsuo H, Kim DK, Fujimura M, Anzai N, Mizoguchi K, Ueda T, Akakura K, Ichikawa T, Ito H, Endou H.
- Journal Title
  
  Kidney Int. 69(7)
  
  Pages: 1198-1206
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Renal elimination of p-aminohippurate(PAH)in respose to three days of biliary obstruction in the rat. The role of OAT1 and OAT32006
- Author(s)
  Brandoni, A, Anzai, N, Kanai, Y, Endou, H, Torres, AM
- Journal Title
  
  Biochim Biophys Acta 1762
  
  Pages: 673-682
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] Regulation of steroid hormone biosynthesis enzymes and organic anion transporters by forskolin and DHEAS treatment in adrenocortical cells2006
- Author(s)
  Asif AR, Ljubojevic M, Sabolic I, Shnitsar V, Metten M, Anzai N, Mueller GA Burckhardt G, Hagos Y.
- Journal Title
  
  Am JPhysiol Endocrinol Metab 291
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] The PDZ domain protein PDZK1 interacts with human peptide transporter PEPT2 and enhances its transport activity.2006
- Author(s)
  Noshiro R, Anzai N, Sakata T, Miyazaki H, Terada T, Shin HJ, He X, Miura D, Inui K, Kanai Y, Endou H.
- Journal Title
  
  Kidney Int.
  
  Pages: 275-282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Functional characterization of rat organic anion transporter 5 (Slc22a19( at the apical membrane of renal proximal tubules2005
- Author(s)
  Anzai N
- Journal Title
  
  J Pharmacol Exp Ther 315(2)
  
  Pages: 534-544
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules2005
- Author(s)
  Anzai N
- Journal Title
  
  J Pharmacol Exp Ther 315(2)
  
  Pages: 534-544
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins.2005
- Author(s)
  Miyazaki H, Anzai N, Ekaratanawong S, Sakata T, Shin HJ, Jutabha P, Hirata T, He X, Nonoguchi H, Tomita K, Kanai Y, Endou H.
- Journal Title
  
  J Am Soc Nephrol.
  
  Pages: 3498-3506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Functional Characterization of rat organic anion transporter 5 (Slc 22a19) at the apical membrane of renal proximal tubules.2005
- Author(s)
  Anzai N
- Journal Title
  
  J Pharmacol Exp Ther 315
  
  Pages: 534-544
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Renal urate handling : clinical relevance of recent advances.2005
- Author(s)
  Anzai N
- Journal Title
  
  Curr Rheumatol Rep. 7
  
  Pages: 227-234
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] Immunocytochemical characterization of the incubated rat renal cortical slices.2005
- Author(s)
  Crljen V, Saboiic I, Susac J, Appenroth D, Herak-Kramberger CM, Ljubojevic M, Anzai N, Antolovic R, Burckhardt G, Fleck C, Sabolic I.
- Journal Title
  
  Pflugers Arch. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins.2005
- Author(s)
  Miyazaki H, Anzai N, Ekaratanawong S, Sakata T, Shin HJ, Jutabha P, Hirata T, He X, Nonoguchi H, Tomita K, Kanai Y, Endou H.
- Journal Title
  
  J Am Soc Nephrol. 16(12)
  
  Pages: 3498-3506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Integrated physiology of proximal tubular organic anion transport.2005
- Author(s)
  Anzai N, Jutabha P, Kanai Y, Endou H.
- Journal Title
  
  Curr Opin Nephrol Hypertens. 14(5)
  
  Pages: 472-479
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Integrated physiology of proximal tubular organic anion transport.2005
- Author(s)
  Anzai N, Jutabha P, Kanai Y, Endou H.
- Journal Title
  
  Curr Opin Nephrol Hypertens. 14(5)
  
  Pages: 472-479
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Integrated physiology of proximal tubular organic anion transport2005
- Author(s)
  Anzai N
- Journal Title
  
  Curr Opin Nephrol Hypertens 14(5)
  
  Pages: 472-479
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureera obsfructton2005
- Author(s)
  Villar SR, Brandon A, Anzai N, Endou H, Torres AM.
- Journal Title
  
  Kidney Int 68
  
  Pages: 2704-2713
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction.2005
- Author(s)
  Villar SR, Brandoni A, Anzai N, Endou H, Torres AM.
- Journal Title
  
  Kidney Int. 68(6)
  
  Pages: 2704-2713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Integrated physiology and proximal tubular organic anion transport.2005
- Author(s)
  Anzai N
- Journal Title
  
  Curr Opin Nephrol Hypertens 14
  
  Pages: 472-479
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] Renal urate handling : clinical relevance of recent advances.2005
- Author(s)
  Anzai N
- Journal Title
  
  Curr Rheumatol Rep. 7
  
  Pages: 227-234
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins.2005
- Author(s)
  Miyazaki H, Anzai N, Ekaratanawong S, Sakata T, Shin HJ, Jutabha P, Hirata T, He X, Nonoguchi H, Tomita K, Kanai Y, Endou H.
- Journal Title
  
  J Am Soc Nephrol. 16(12)
  
  Pages: 3498-3506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Functional Characterization of rat organic anion transporter 5 (Slc 22a19) at the apical membrane of renal proximal tubules.2005
- Author(s)
  Anzai N
- Journal Title
  
  J Pharmacol Exp Ther 315
  
  Pages: 534-544
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] Renal urate handling:clinical relevance of recent advances2005
- Author(s)
  Anzai N, Enomoto A, Endou H
- Journal Title
  
  Curr Rheumatol Rep 7
  
  Pages: 227-234
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] Renal Urate Handling : Clinical Relevance of Recent Advances.2005
- Author(s)
  Anzai N.
- Journal Title
  
  Current Rheumatology Report 7
  
  Pages: 227-234
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules.2005
- Author(s)
  Anzai N, Jutabha P, Enomoto A, Yokoyama H, Nonoguchi H, Hirata T, Shiraya K, He X, Cha SH, Takeda M, Miyazaki H, Sakata T, Tomita K, Igarashi T, Kanai Y, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther. 315(2)
  
  Pages: 534-544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Altered renal elimination of organic anions in rats with chronic renal failure.2005
- Author(s)
  Torres AM, Mac Laughlin M, Muller A, Brandoni A, Anzai N, Endou H.
- Journal Title
  
  Biochim Biophys Acta. 1740(1)
  
  Pages: 29-37
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Altered renal elimination of organic anions in rats with chronic renal failure2005
- Author(s)
  Monica Torres A, Mac Laughlin M, Muller A, Brandoni A, Anzai N, Endou H
- Journal Title
  
  Biochim Biophys Acta 1740
  
  Pages: 29-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590226
[Journal Article] Renal Urate Handling Clinical Relevance of Recent Advances.2005
- Author(s)
  Anzai N, Enomoto A, Endou H.
- Journal Title
  
  Curr Rheumatol Report 7(3)
  
  Pages: 227-234
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Integrated Physiology of proximal tubular organic anion transport.2005
- Author(s)
  Anzai N, Jutabha P, Kanai Y, Endou H.
- Journal Title
  
  Curr Opin Nephrol Hypertens (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Functional characterization of rat organic anion transporter 5 (Slc22a19) at the apical membrane of renal proximal tubules.2005
- Author(s)
  Anzai N, Jutabha P, Enomoto A, Yokoyama H, Nonoguchi H, Hirata T, Shiraya K, He X, Cha SH, Takeda M, Miyazaki H, Sakata T, Tomita K, Igarashi T, Kanai Y, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther. 315(2)
  
  Pages: 534-544
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Altered expression of rat renal cortical OAT1 and OAT3 in response to bilateral ureteral obstruction.2005
- Author(s)
  Villar SR, Brandoni A, Anzai N, Endou H, Torres AM.
- Journal Title
  
  Kidney Int. 68(6)
  
  Pages: 2704-2713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Integrated physiology and proximal tubular organic anion transport.2005
- Author(s)
  Anzai N
- Journal Title
  
  Curr Opin Nephrol Hypertens 14
  
  Pages: 472-479
- Data Source
  KAKENHI-PROJECT-17081016
[Journal Article] Integrated physiology of proximal tubular organic anion transport2005
- Author(s)
  Anzai N
- Journal Title
  
  Curr Opin Nephrol Hypertens 14(5)
  
  Pages: 472-479
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal orate-anion exchanger URAT1 via its C terminus.2004
- Author(s)
  Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H.
- Journal Title
  
  J Biol Chem. 279(44)
  
  Pages: 45942-45950
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] 尿酸トランスポーターの分子生物学2004
- Author(s)
  安西尚彦
- Journal Title
  
  生化学 76
  
  Pages: 101-110
- NAID
  10012684851
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions.2004
- Author(s)
  Sakata T, Anzai N, Shin HJ, Noshiro R, Hirata T, Yokoyama H, Kanai Y, Endou H.
- Journal Title
  
  Biochem Biophys Res Commun. 313(3)
  
  Pages: 789-793
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules.2004
- Author(s)
  Ekaratanawong, S., N.Anzai, et al.
- Journal Title
  
  J Pharmacol Sci 94-3
  
  Pages: 297-304
- NAID
  130000073849
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590858
[Journal Article] Mutations in SLC6A19, encoding B^0AT 1, cause Hartnup disorders.2004
- Author(s)
  Kleta R, Romeo E, Ristic Z, Ohura T, Stuart C, Arcos-Burgos M, Dave MH, Wagner CA, Camargo SR, Inoue S, Matsuura N, Helip-Wooley A, Bockenhauer D, Warth R, Bernardini I, Visser G, Eggermann T, Lee P, Chairoungdua A, Jutabha P, Babu E, Nilwarangkoon S, Anzai N, Kanai Y, Verrey F, Gahl WA, Koizumi A.
- Journal Title
  
  Nat Genet. 36(9)
  
  Pages: 999-1002
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Novel single nucleotide polymorphisms of organic cation transporter 1(SLC22A1) affecting transport functions.2004
- Author(s)
  Sakata T, Anzai N, Shin HJ, Noshiro R, Hirata T, Yokoyama H, Kanai Y, Endou H.
- Journal Title
  
  Biochem Biophys Res Commun. 313(3)
  
  Pages: 789-793
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Novel single nucleotide polymorphisms of organic cation transporter 1(SLC22A1) affecting transport functions.2004
- Author(s)
  Sakata T, Anzai N, Shin HJ, Norhiro R, Hirata T, Yokoyama H, Kanai Y, Endou H.
- Journal Title
  
  Biochem Biophys Res Comm. 313
  
  Pages: 789-793
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Novel single nucleotide polymorphisms of organic cation transporter 1(SLC22A1) affecting transport functions.2004
- Author(s)
  Sakata T, Anzai N, Shin HJ, Norhiro R, Hirata T, Yokoyama H, Kanai Y, Endou H.
- Journal Title
  
  Biochem Biophys Res comm. 313
  
  Pages: 789-793
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.2004
- Author(s)
  Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H
- Journal Title
  
  J Biol Chem 279(44)
  
  Pages: 45942-45950
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The multivalent PDZ-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.2004
- Author(s)
  Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H.
- Journal Title
  
  J Biol Chem. 279(44)
  
  Pages: 45942-45950
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] The genetic polymorphism of drub transporters : functional analysis approaches.2004
- Author(s)
  Ishikawa T, Tsuji A, Inui K, Sai Y, Anzai N, Wada M, Endou H, Sumino Y
- Journal Title
  
  Phamacogeneomics 5(1)
  
  Pages: 67-99
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules.2004
- Author(s)
  Ekaratanawong, S., N.Anzai, et al.
- Journal Title
  
  J Pharmacol Sci 94(3)
  
  Pages: 297-304
- NAID
  130000073849
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590858
[Journal Article] Human organic anion transporter 4 is a renal apical organic anion / dicarboxylate exchanger in the proximal tubules.2004
- Author(s)
  Ekaratanawong S, Anzai N, Jutabha P, Miyazaki H, Moshiro R, Takeda M, Kanai, Endou, H.
- Journal Title
  
  Pharmacol Sci 94
  
  Pages: 297-304
- NAID
  130000073849
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Interactions of human organic anion transporters with diuretics.2004
- Author(s)
  Hasannejad H, Takeda M, Taki K, Jung SH, Babu E, Jutabha P, Khamdang S, Aleboyeh M, Onodera ML, Tojo A, Enomoto A, Anzai N, Narikawa S, Huang XL, Niwa T, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther. 308(3)
  
  Pages: 1021-1029
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] The multivalent PDZ -containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus2004
- Author(s)
  Anzai N
- Journal Title
  
  J Biol Chem 279(44)
  
  Pages: 45942-45950
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions.2004
- Author(s)
  Sakata T, Anzai N, Shin HJ, Noshiro R, Hirata T, Yokoyama H, Kanai Y, Endou H.
- Journal Title
  
  Biochem Biophys Res Commun. 313(3)
  
  Pages: 789-793
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C-terminal.2004
- Author(s)
  Anzai N.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 45942-45950
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] The multivalent PDZ -containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus2004
- Author(s)
  Anzai N
- Journal Title
  
  J BIol CHem 279(44)
  
  Pages: 45942-45950
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The multivalent PDZ-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.2004
- Author(s)
  Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H.
- Journal Title
  
  J Biol Chem. 279(44)
  
  Pages: 45942-45950
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.2004
- Author(s)
  Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H
- Journal Title
  
  J Biol Chem 279(44)
  
  Pages: 45942-45950
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570085
[Journal Article] Mutations in SLC6A19, encoding BOAT1, cause Hartnup disorder.2004
- Author(s)
  Kleta R, Romeo E, Ristic Z, Ohura T, Stuart C, Arcos-Burgos M, Dave MH, Wagner CA, Camargo SR, Inoue S, Matsuura N, Helip-Wooley A, Bockenhauer D, Warth R, Bernardini I, Visser G, Eggermann T, Lee P, Chairoungdua A, Jutabha P, Babu E, Nilwarangkoon S, Anzai N, Kanai Y, Verrey F, Gahl WA, Koizumi A
- Journal Title
  
  Nat Genet 36(9)
  
  Pages: 999-1002
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570085
[Journal Article] Human organic anion transporter 4 is a renal apical organis anion / dicarboxylate exchanger in the proximal tubules.2004
- Author(s)
  Ekaratanawong S, Anzai N, Jutabha P, Miyazaki H, Noshiro R, Takeda M, Kanai, Endou H.
- Journal Title
  
  Pharmacol Sci 94
  
  Pages: 297-304
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C-terminal.2004
- Author(s)
  Anzai N.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 45942-45950
- Data Source
  KAKENHI-PROJECT-16023263
[Journal Article] The genetic polymorphism of drub transporters : functional analysis approaches.2004
- Author(s)
  Ishikawa T, Tsuji A, Inui K, Sai Y, Anzai N, Wada M, Endou H, Sumino Y
- Journal Title
  
  Phamacogeneomics 5(1)
  
  Pages: 67-99
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules.2004
- Author(s)
  Ekaratanawong S, Anzai N, Jutabha P, Miyazaki H, Noshiro R, Takeda M, Kanai Y, Sophasan S, Endou H
- Journal Title
  
  J Pharmacol Sci 94(3)
  
  Pages: 297-304
- NAID
  130000073849
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570085
[Journal Article] Interactions of human organic anion transporters with diuretics.2004
- Author(s)
  Hasannejad H, Takeda M, Taki K, Shin HJ, Babu E, Jutabha P, Khamdang S, Aleboyeh M, Onozato ML, Tojo A, Enomoto A, Anzai N, Narikawa S, Huang XL, Niwa T, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther. 308(3)
  
  Pages: 1021-1029
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Interactions of human organic anion transporters with diuretics.2004
- Author(s)
  Hasannejad H, Takeda M, Taki K, Jung SH, Babu F, Jutabha P, Khamdang S, Aleboyen M, Onodera ML, Tojo A, Enomoto A, Anzai N, Narikawa S, Huang XL, Niwa T, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther. 308(3)
  
  Pages: 1021-1029
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.2004
- Author(s)
  Anzai N
- Journal Title
  
  J Biol Chem. 279(44)
  
  Pages: 45942-45950
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570085
[Journal Article] The multivalent PDZ domain-containing protain PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C-terminal.2004
- Author(s)
  Anzai N.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 45942-45950
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Interactions of human organic anion transporters with diuretics.2004
- Author(s)
  Hasanne jad H, Takeda M, Taki K, Shin HJ, Babu E, Jutabha P, Khamdang S, Aleboyeh M, Onozato ML, Tojo A, Enomoto A, Anzai N, Narikawa S, Huang XL, Niwa T, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther. 308(3)
  
  Pages: 1021-1029
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Interactions of human organic anion transporters with diuretics.2004
- Author(s)
  Hasannejad H, Takeda M, Taki K, Jung SH, Babu E, Jutabha P, Khamdang S, Aleboyen M, Onodera ML, Tojo A, Enomoto A, Anzai N, Narikawa S, Huang XL, Niwa T, Endou H.
- Journal Title
  
  J Pharmacol Exp Ther 308(3)
  
  Pages: 1021-1029
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Human organic anion transporter 4 (OAT4) is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules.2004
- Author(s)
  Ekaratanawong S, Anzai N, Jutabha P, Miyazaki H, Noshiro R, Takeda M, Kanai Y, Sophasan S, Endou H
- Journal Title
  
  J Pharmacol Sci. 94(3)
  
  Pages: 297-304
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] The genetic polymorphism of drug transporters : functional analysis approaches.2004
- Author(s)
  Ishikawa T, Tsuji A, Inui K, Sai Y, Anzai N, Wada M, Endou H, Sumino Y
- Journal Title
  
  Pharmacogenomics. 5(1)
  
  Pages: 67-99
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions.2004
- Author(s)
  Sakata T, Anzai N, Shin HJ, Noshiro R, Hirata T, Yokoyama H, Kanai Y, Endou H
- Journal Title
  
  Biochem Biophys Res Commun 313(3)
  
  Pages: 789-793
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570085
[Journal Article] Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubles.2004
- Author(s)
  Ekaratanawong, S., N.Anzai, et al.
- Journal Title
  
  J Pharmacol Sci 94(3)
  
  Pages: 297-304
- Data Source
  KAKENHI-PROJECT-15590858
[Journal Article] The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.2004
- Author(s)
  Anzai N, Miyazaki H, Noshiro R, Khamdang S, Chairoungdua A, Shin HJ, Enomoto A, Sakamoto S, Hirata T, Tomita K, Kanai Y, Endou H
- Journal Title
  
  J Biol Chem 279(44)
  
  Pages: 45942-45950
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule.2003
- Author(s)
  Jutabha P, Kanai Y, Hosoyamada M, Chairoungdua A, Kim do K, Iribe Y, Babu E, Kim JY, Anzai N, Chatsudthipong V, Endou H
- Journal Title
  
  J Biol Chem 278(30)
  
  Pages: 27930-27938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570085
[Journal Article] Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule.2003
- Author(s)
  Jutabha P, Kanai Y, Hosoyamada M, Chairoungdua A, Kim do K, Iribe Y, Babu E, Kim JY, Anzai N, Chatsudthipong V, Endou H.
- Journal Title
  
  J Biol Chem. 278(30)
  
  Pages: 27930-27938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters.2003
- Author(s)
  Babu E, Kanai Y, Chairoungdua A, Kim do K, Iribe Y, Tangtrongsup S, Jutabha P, Li Y, Ahmed N, Sakamoto S, Anzai N, Nagamori S, Endou H.
- Journal Title
  
  J Biol Chem. 278(44)
  
  Pages: 43838-43845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.2003
- Author(s)
  Khamdang S, Takeda M, Babu E, Noshiro R, Onozato ML, Tojo A, Enomoto A, Huang XL, Narikawa S, Anzai N, Piyachaturawat P, Endou H.
- Journal Title
  
  Eur J Pharmacol. 465(1-2)
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters.2003
- Author(s)
  Babu E, Kanai Y, Chairoungdua A, Kim do K, Iribe Y, Tangtrongsup S, Jutabha P, Li Y, Ahmed N, Sakamoto S, Anzai N, Nagamori S, Endou H
- Journal Title
  
  J Biol Chem 278(44)
  
  Pages: 43838-43845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570085
[Journal Article] Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.2003
- Author(s)
  Khamdang S, Takeda M, Babu E, Noshiro R, Onozato ML, Tojo A, Enomoto A, Huang XL, Narikawa S, Anzai N, Piyachaturawat P, Endou H.
- Journal Title
  
  Eur J Pharmacol. 465(1-2)
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters.2003
- Author(s)
  Babu E, Kanai Y, Chairoungdua A, Kim do K, Iribe Y, Tangtrongsup S, Jutabha P, Li Y, Ahmed N, Sakamoto S, Anzai N, Nagamori S, Endou H.
- Journal Title
  
  J Biol Chem. 278(44)
  
  Pages: 43838-43845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule.2003
- Author(s)
  Jutabha P, Kanai Y, Hosoyamada M, Chairoungdua A, Kim do K, Iribe Y, Babu E, Kim JY, Anzai N, Chatsudthipong V, Endou H.
- Journal Title
  
  J Biol Chem. 278(30)
  
  Pages: 27930-27938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Expression of human organic anion transporters in the choroid plexus and their interactions with neurotransmitter metabolites.2003
- Author(s)
  Alebouyeh M, Takeda M, Onozato ML, Tojo A, Noshiro R, Hasannejad H, Inatomi J, Narikawa S, Huang XL, Khamdang S, Anzai N, Endou H.
- Journal Title
  
  J Pharmacol Sci. 93(4)
  
  Pages: 430-436
- NAID
  10011953460
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590233
[Journal Article] Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule.2003
- Author(s)
  Jutabha P, Kanai Y, Hosoyamada M, Chairoungdua A, Kim do K, Iribe Y, Babu E, Kim JY, Anzai N, Chatsudthipong V, Endou H.
- Journal Title
  
  J Biol Chem. 278(30)
  
  Pages: 27930-27938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.2003
- Author(s)
  Khamdang S, Takeda M, Babu E, Noshiro R, Onozato ML, Tojo A, Enomoto A, Huang XL, Narikawa S, Anzai N, Piyachaturawat P, Endou H.
- Journal Title
  
  Eur J Pharmacol. 465(1-2)
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters.2003
- Author(s)
  Babu E, Kanai Y, Chairoungdua A, Kim do K, Iribe Y, Tangtrongsup S, Jutabha P, Li Y, Ahmed N, Sakamoto S, Anzai N, Nagamori S, Endou H.
- Journal Title
  
  J Biol Chem. 278(44)
  
  Pages: 43838-43845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Molecular identication of a novel carnitine transporter specific of human testis.2002
- Author(s)
  Enomoto A, Wempe MF, Tsuchida H, Shin HJ, Cha SH, Anzai N, Goto A, Sakamoto A, niwa T, Kanai Y, Anders MW, Endou H.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 36262-26271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13376004
[Journal Article] Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition.2002
- Author(s)
  Enomoto A, Wempe MF, Tsuchida H, Shin HJ, Cha SH, Anzai N, Goto A, Sakamoto A, Niwa T, Kanai Y, Anders MW, Endou H
- Journal Title
  
  J Biol Chem 277(39)
  
  Pages: 36262-36271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570085
[Journal Article] Molecular identication of a novel carnitine transporter specific of human testis.2002
- Author(s)
  Enomoto A, Wempe MF, Tsuchida H, Shin HJ, Cha SH, Anzai N, Goto A, Sakamoto A, niwa T, Kanai Y, Anders MW, Endou H.
- Journal Title
  
  J Biol Chem 277
  
  Pages: 36262-26271
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207004
[Journal Article] Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells.2002
- Author(s)
  Kim do K, Kanai Y, Choi HW, Tangtrongsup S, Chairoungdua A, Babu E, Tachampa K, Anzai N, Iribe Y, Endou H
- Journal Title
  
  Biochim Biophys Acta 1565(1)
  
  Pages: 112-121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570085
[Journal Article] Sodium-dependent phosphate cotransporter type 1 (NPT1) sequence polymorphisms in male patients with gout.
- Author(s)
  Urano W, Taniguchi A, Anzai N, Inoue E, Kanai Y, et al.
- Journal Title
  
  Ann Rheum Dis.(電子版) (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17081016
[Patent] 免疫抑制剤2013
- Inventor(s)
  林啓太朗、安西尚彦
- Industrial Property Rights Holder
  ジェイファーマ株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2013-08-20
- Acquisition Date
  2014-02-14
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 前立腺癌細胞におけるアミノ酸トランスポーターLAT3の機能解析及び下流シグナルの同定2021
- Author(s)
  梨井隼菱,坂本信一, 杉浦正洋, 金坂学斗, 若井健, 金田篤志, 池原譲, 安西尚彦, 金井好克, 市川智彦
- Organizer
  第109回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-20K09555
[Presentation] まれな変異に重点を置いた尿酸値の遺伝率の研究2021
- Author(s)
  三澤計治, 長谷川嵩矩, 三島英換, 大内基司, 小島要, 河合洋介, 松尾雅文, 安西尚彦, 長崎正朗
- Organizer
  日本人類遺伝学会第66回大会第28回日本遺伝子診療学会大会合同開催
- Data Source
  KAKENHI-PROJECT-20K07316
[Presentation] Effects of trypsin inhibition on endocrine function in isolated rat pancreas2021
- Author(s)
  Morita Asuka、Ouchi Motoshi、Satoh Keitaro、Kobayashi Shunsuke、Anzai Naohiko、Shimizu Akira、Sugihara Hitoshi、Oba Kenzo、Fujita Tomoe
- Organizer
  Experimental Biology (EB)　2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11629
[Presentation] 尿酸値の失われた遺伝率は、レアバリアントがかなりの部分を説明する2021
- Author(s)
  三澤計治, 長谷川嵩矩, 三島英換, Promsuk Jutabha, 大内基司, 小島要, 河合洋介, 松尾雅文, 安西尚彦, 長崎正朗
- Organizer
  日本遺伝学会第93回大会
- Data Source
  KAKENHI-PROJECT-20K07316
[Presentation] ヒトの尿酸代謝：腸腎連関の解明に向けて2020
- Author(s)
  安西尚彦、大内基司
- Organizer
  第51回日本消化吸収学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08200
[Presentation] ラット摘出膵を用いた簡易インスリン分泌評価実験系の有効性検討と至適化2020
- Author(s)
  森田亜州華、大内基司、佐藤慶太郎、小林俊介、安西尚彦、大庭建三、杉原仁、清水章、藤田朋恵
- Organizer
  第63回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K11629
[Presentation] ラット膵インスリン分泌評価におけるex vivo実験系の応用　―1,5-AGの効果を検証する先行研究―2020
- Author(s)
  大内基司、森田亜州華、佐藤慶太郎、小林俊介、清水章、安西尚彦、杉原仁、大庭建三、藤田朋恵
- Organizer
  第93回　日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K11629
[Presentation] New Drug Development targeting Membrane Transporters2019
- Author(s)
  Anzai N
- Organizer
  The Chiba-Ottawa Joint Session of Pharmacology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08200
[Presentation] URAT1：尿酸輸送体か有機酸輸送体か2019
- Author(s)
  安西尚彦
- Organizer
  第41回生体膜と薬物の相互作用シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K08200
[Presentation] Renal tubular transporters: relation to renal drug disposition and drug-induced nephropathy2019
- Author(s)
  Naohiko Anzai
- Organizer
  第７回日中腎病理カンファレンス
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08200
[Presentation] トランスポーター：疾患発症と治療薬作用の分子機序2019
- Author(s)
  安西尚彦
- Organizer
  第29回臨床内分泌代謝Update MTE16
- Invited
- Data Source
  KAKENHI-PROJECT-18K08200
[Presentation] Hyperuricemia as a rsk factor for CKD: Improvement of acidic urine by basic alkalogenic-drug and urate transporters2019
- Author(s)
  Anzai N
- Organizer
  ISARSH2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08200
[Presentation] 腎尿細管トランスポーターによる尿酸・グルコース輸送とSGLT2阻害薬tofogliflozinの阻害効果2019
- Author(s)
  安西尚彦, 大内基司
- Organizer
  第52回日本痛風・核酸代謝学会総会
- Data Source
  KAKENHI-PROJECT-18K08200
[Presentation] Renal tubular urate transporters as targets of drug development2019
- Author(s)
  Naohiko Anzai
- Organizer
  第22回日韓薬理学合同セミナー
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08200
[Presentation] 腎尿酸トランスポーターと血清尿酸値異常2019
- Author(s)
  安西尚彦
- Organizer
  日本薬学会東海支部講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08200
[Presentation] 栄養代謝における腸管トランスポーターの働き2018
- Author(s)
  安西尚彦, 大内基司
- Organizer
  第41回日本栄養アセスメント研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08200
[Presentation] 近位尿細管上皮輸送：有機溶質の再吸収と分泌2017
- Author(s)
  安西尚彦
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2017-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] モノカルボン酸トランスポーター９(MCT9)によるβヒドロキシ酪酸輸送2017
- Author(s)
  JUTABHA Promsuk、大内基司、安西尚彦
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] 尿酸代謝と腎尿細管尿酸トランスポーター2017
- Author(s)
  安西尚彦、JUTABHA Promsuk、大内基司
- Organizer
  第50回日本痛風・核酸代謝学会総会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2017-02-16
- Invited
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] Substrate Recognition of an Amino Acid Transporter 3 (LAT3)2017
- Author(s)
  Toru Oba, Rino Iwakami, Kota Miyata, Promsuk Jutabha, Naohiko Anzai
- Organizer
  第54回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-17K08959
[Presentation] ヒトの血清尿酸値制御の分子機序2016
- Author(s)
  安西尚彦、大内基司、大谷直由、JUTABHA Promsuk
- Organizer
  第39回日本高血圧学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-30
- Invited
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] Renal tubular urate transporters as targets for new drug discovery and development2016
- Author(s)
  Anzai N
- Organizer
  The 13th Asia Pacific Federation of Pharmacologists (APFP) meeting
- Place of Presentation
  Bangkok (Thailand)
- Year and Date
  2016-02-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] アンセリンによる尿酸降下作用の分子機序解明2016
- Author(s)
  大塚裕介、森田亜州華、堀　貴行、大谷直由、Jutabha P, 大内基氏、鶴岡秀一、安西尚彦
- Organizer
  第49回日本痛風・核酸代謝学会総会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府・豊中市）
- Year and Date
  2016-02-18
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] Monocarboxylate transporter 9 is a novel rate transporter in kidney.2016
- Author(s)
  Jutabha P, Otani N, Ouchi M, Anzai N.
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] 腎排泄低下型動物モデルの創製とカルシウム拮抗薬の尿酸降下作用の検討2016
- Author(s)
  堀貴行, 福田宏嗣, 安西尚彦, et al.
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜市
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25670600
[Presentation] 腎尿酸排泄低下型動物モデルの創製とカルシウム拮抗薬の尿酸降下作用の検討2016
- Author(s)
  堀　貴行、大谷直由、大野雄太、大内基氏、福田宏嗣、安西尚彦
- Organizer
  第８9回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] アミノ酸トランスポーターLAT1阻害薬による血管形成阻害2015
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] Suppressive Effects of LAT1-Specific Inhibitor on the Activation of Human T Cells.2015
- Author(s)
  Hayashi K, H Anzai.
- Organizer
  13th Cytokines & Inflammation Conference
- Place of Presentation
  San Diego
- Year and Date
  2015-01-29
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 必須アミノ酸トランスポーターLAT1の機能阻害による破骨細胞分化の抑制2014
- Author(s)
  林啓太朗、安西尚彦
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-07-04
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 必須アミノ酸トランスポーターLAT1阻害薬の胸腺がんに対する増殖抑制効果2014
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 尿酸トランスポーターの分子同定2013
- Author(s)
  安西尚彦
- Organizer
  第46回日本痛風・核酸代謝学会総会
- Place of Presentation
  新宿区(招待講演)
- Data Source
  KAKENHI-PROJECT-23659447
[Presentation] Induction of expression of LAT1, an essential amino acids transporter, in activated T cells2013
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  米国免疫学会年会
- Place of Presentation
  ホノルル（米国）
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 尿酸トランスポーターの分子同定2013
- Author(s)
  安西尚彦
- Organizer
  第46回日本痛風・核酸代謝学会総会
- Place of Presentation
  新宿区
- Invited
- Data Source
  KAKENHI-PROJECT-23659447
[Presentation] ヒトの尿酸代謝と高尿酸血症治療2012
- Author(s)
  安西尚彦
- Organizer
  第33回日本臨床薬理学会総会
- Place of Presentation
  沖縄県(招待講演)
- Data Source
  KAKENHI-PROJECT-23659447
[Presentation] 腎尿酸輸送の分子機序2012
- Author(s)
  安西尚彦
- Organizer
  第45回日本痛風・核酸代謝学会総会学会賞受賞講演
- Place of Presentation
  奈良
- Year and Date
  2012-02-16
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] トランスポーター研究2012
- Author(s)
  安西尚彦、Promsuk Jutabha
- Organizer
  第45回日本痛風・核酸代謝学会総会シンポジウム1「核酸代謝の研究はいかに生命科学の発展に寄与したか」
- Place of Presentation
  奈良
- Year and Date
  2012-02-16
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] ランスポーター:腎臓からの全身制御を目指して2012
- Author(s)
  安西尚彦
- Organizer
  第47回日本小児腎臓学会学術集会
- Place of Presentation
  千代田区(招待講演)
- Data Source
  KAKENHI-PROJECT-23659447
[Presentation] ヒトの尿酸代謝と高尿酸血症治療2012
- Author(s)
  安西尚彦
- Organizer
  第33回日本臨床薬理学会総会
- Place of Presentation
  沖縄県
- Invited
- Data Source
  KAKENHI-PROJECT-23659447
[Presentation] トランスポーター：腎臓からの全身制御を目指して2012
- Author(s)
  安西尚彦
- Organizer
  第47回日本小児腎臓学会学術集会
- Place of Presentation
  千代田区
- Invited
- Data Source
  KAKENHI-PROJECT-23659447
[Presentation] オーバービュー:疾患発症の基本ユニットとしてのトランスポートソーム2011
- Author(s)
  安西尚彦
- Organizer
  第84回日本薬理学会年会シンポジウムS2C19 トランスポートソームの破綻による疾患と創薬標的としての可能性～次世代のトランスポーター研究を目指して～
- Place of Presentation
  横浜
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 腎尿酸トランスポーター遺伝子改変マウスを用いた高尿酸血症発症機序の解明2011
- Author(s)
  安西尚彦、木村徹^1(^1 杏林大・医)
- Organizer
  第54回日本腎臓学会学術総会ワークショップ1 腎疾患・病態の理解を目指すトランスポーター遺伝子改変動物の利用
- Place of Presentation
  横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] Regulation of serum uric acid levels by epithelial transporters2011
- Author(s)
  Naohiko Anzai
- Organizer
  Epithelial Transport - expanding the boundaries. ASCEPT-AuPS-HBPRCA Joint Meeting
- Place of Presentation
  Perth
- Year and Date
  2011-12-06
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 尿酸と高血圧～臓器保護のための尿酸管理～2011
- Author(s)
  安西尚彦
- Organizer
  第34回日本高血圧学会総会モーニングセミナー4
- Place of Presentation
  宇都宮
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] Renal tubular urate transporters and gout. Symposium 2:Epithelial transporters: properties, regulation and relation to diseases2011
- Author(s)
  Naohiko Anzai
- Organizer
  7th FAOPS Congress
- Place of Presentation
  Taipei
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 研究の推進に向けて2011
- Author(s)
  安西尚彦
- Organizer
  第32回日本臨床薬理学会年会ワークショップ5臨床薬理学のあり方、今後の展望
- Place of Presentation
  浜松
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] Renal urate transporters and hyperuricemia2011
- Author(s)
  Naohiko Anzai
- Organizer
  International Joint Meeting of Cellular and Molecular Physiology in Epithelia
- Place of Presentation
  港区
- Year and Date
  2011-07-30
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] Regulation of serum uric acid levels by epithelial transporters2011
- Author(s)
  Anzai N
- Organizer
  ASCEPT AuPS HBPRCA Joint Meeting
- Place of Presentation
  Perth, Australia(招待講演)
- Year and Date
  2011-12-06
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] Reanl urate reabsorptive transporters : putative roles for the onset of hy peruricemia.2011
- Author(s)
  Naohiko Anzai
- Organizer
  14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP11
- Place of Presentation
  新宿
- Year and Date
  2011-02-19
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] URAT1 阻害の意義2011
- Author(s)
  安西尚彦
- Organizer
  第54回日本腎臓学会学術総会イブニングセミナー
- Place of Presentation
  横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 腎尿細管上皮尿酸輸送とPDZタンパク質2011
- Author(s)
  安西尚彦
- Organizer
  第88回日本生理学会大会第110 回日本解剖学会総会・全国学術集会シンポジウム5 上皮機能の分子機序:細胞内タンパク質が支持する有機溶質トランスポートソーム
- Place of Presentation
  横浜
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] Renal urate reabsorptive transporters: putative roles for the onset of hyperuricemia. Session 3 Association between genomic variation and urate metabolism2011
- Author(s)
  Naohiko Anzai
- Organizer
  14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP11
- Place of Presentation
  新宿
- Year and Date
  2011-02-19
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 新規尿酸トランスポーターの分子同定:ヒト尿酸代謝の全貌解明に向けて2011
- Author(s)
  安西尚彦、Jutabha Promsuk、福冨俊之、木村徹、三浦大作^1(^1 兵庫医療大・薬)
- Organizer
  日本薬学会第131 年会一般シンポジウムS18 痛風・高尿酸血症:最近の進歩
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 利尿薬とトランスポーター:尿酸変動を考慮した高血圧治療2011
- Author(s)
  安西尚彦
- Organizer
  第41回日本腎臓学会東部学術大会ランチョンセミナー
- Place of Presentation
  新宿
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 腎臓における有機酸輸送2010
- Author(s)
  安西尚彦、Jutabha Promsuk、木村徹、福冨俊之
- Organizer
  第54回日本薬学会関東支部大会シンポジウム2「トランスポーター研究の最前線」
- Place of Presentation
  八王子
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] Isoform specific tissue distribution of URATv1/GLUT9 and their trafficking in the polarized cells.2010
- Author(s)
  Toru Kimura, Anzai Naohiko, Hiroyuki Sakurai
- Organizer
  50^<th> The American Society for Cell Biology Annual Meeting
- Place of Presentation
  アメリカフィラデルフィア
- Year and Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-21790819
[Presentation] 腎尿細管利尿薬分泌経路の分子機序:新規ヒト電位依存性有機酸トランスポーターhOATv1 の同定2010
- Author(s)
  安西尚彦、Promsuk Jutabha、福冨俊之、木村徹、遠藤仁、櫻井裕之
- Organizer
  第122 回日本薬理学会関東部会ミニシンポジウム3 チャネル・トランスポーターの薬理学
- Place of Presentation
  静岡
- Year and Date
  2010-06-05
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 高尿酸血症の発症機序解明および新規治療薬創製を目指した尿酸輸送体過剰発現マウスの解析2010
- Author(s)
  木村徹、安西尚彦、金井好克^1、櫻井裕之(^1 阪大院・医)
- Organizer
  第2 回FRONT-J スペシャルシンポジウム「腎尿細管トランスポーター:遺伝子改変動物を用いた疾患・病態の理解」
- Place of Presentation
  中央区
- Year and Date
  2010-08-21
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] ヒト電位依存性尿酸トランスポーターURATv1 (SLC2A9):経尿細管上皮性尿酸再吸収の分子機序2010
- Author(s)
  安西尚彦
- Organizer
  第87回日本生理学会大会シンポジウム6 有機溶質のトランスポーター:基質輸送の電気生理学的特性と病態との関連
- Place of Presentation
  盛岡
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 「尿酸代謝とその異常」基礎2010
- Author(s)
  安西尚彦
- Organizer
  第53回日本腎臓学会学術総会特別企画3よくわかるシリーズ9尿酸代謝とその異常
- Place of Presentation
  神戸
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 腎臓の有機酸輸送:尿細管管腔側有機酸排出の分子機序2010
- Author(s)
  安西尚彦、Jutabha Promsuk、木村徹、福冨俊之
- Organizer
  トランスポーター研究会第4回九州部会シンポジウム「膜輸送研究の最前線」
- Place of Presentation
  長崎
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 高尿酸血症合併高血圧の治療戦略:尿酸トランスポーター制御の観点から2010
- Author(s)
  安西尚彦
- Organizer
  第40回日本腎臓学会東部学術大会ランチョンセミナー
- Place of Presentation
  宇都宮
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 新規尿酸トランスポーターURATv1(SLC2A9)遺伝子変異と腎性低尿酸血症2009
- Author(s)
  安西尚彦
- Organizer
  第42回日本痛風・核酸代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2009-02-19
- Data Source
  KAKENHI-PROJECT-20590965
[Presentation] 腎臓の尿酸トランスポーター:ロサルタンによる尿酸降下作用2009
- Author(s)
  安西尚彦
- Organizer
  第22回多摩アンギオテンシン研究会
- Place of Presentation
  武蔵野
- Year and Date
  2009-06-23
- Data Source
  KAKENHI-PROJECT-21390073
[Presentation] 新規尿酸トランスポーターURATv1(SLC2A9)の輸送特性と腎性低尿酸血症に見られた遺伝子変異2008
- Author(s)
  安西尚彦
- Organizer
  第29回日本臨床薬理学会年会
- Place of Presentation
  東京
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-20590965
[Presentation] Interaction of the multivalent PDZ "domain protein PDZK1 with novel liver-specific organic anion transporter 72008
- Author(s)
  Anzai N. Shin H, Miyao K, Endou H
- Organizer
  Experimental Biology 2008
- Place of Presentation
  San Diego, USA
- Year and Date
  2008-04-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Presentation] Renal Drug Transporters and Nephrotoxicity2007
- Author(s)
  Naohiko Anzai. Hitoshi Endou
- Organizer
  6th World Congress on Alternatives & Animal Use in the Life Sciences
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-08-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Presentation] Immunolocalization of G-protein-coupled receptors for succinate (GPR91) and a -ketoglutarate (GPR99) in the human nephron2007
- Author(s)
  Naohiko Anzai, Vedran Micek, Hrvoje Brzica, Hermann Koepsell, Ivan Sabolic
- Organizer
  5th International Symposium on receptor Mechanisms, Signal Transduction and drug Effects
- Place of Presentation
  Shizuoka, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Presentation] 有機イオンの細胞膜輸送:トランスポーターの基礎と臨床2007
- Author(s)
  安西尚彦
- Organizer
  第3回JPC/JCNRA合同プテリジン研究会
- Place of Presentation
  東京都板橋区
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-18590900
[Presentation] 有機アニオントランスポーター:腎尿細管上皮輸送における新たな展開2007
- Author(s)
  金井好克, 安西尚彦, 平田拓, 木村徹, 上野剛, 福冨俊之
- Organizer
  第84回日本生理学会大会
- Place of Presentation
  大阪
- Year and Date
  2007-03-22
- Data Source
  KAKENHI-PROJECT-17081016
[Presentation] 有機イオンの細胞膜輸送 : トランスポーターの基礎と臨床2007
- Author(s)
  安西尚彦
- Organizer
  第3回JPC/JCNRA合同プテリジン研究会
- Place of Presentation
  東京都板橋区
- Year and Date
  2007-07-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Presentation] Transcellular transport of organic ions: Basic and clinical importance of transporters2007
- Author(s)
  Naohiko Anzai
- Organizer
  3^<rd> joint meeting of JPC/JCNRA
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2007-07-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Presentation] Heterodimeric amino acid transporters : protein-protein interactions for membrane targeting cellular signaling2007
- Author(s)
  Yoshikatsu Kanai, Naohiko Anzai. Taku Hirata, Takeshi Ueno, Toru Kimura, Toshiyuki Fukutomi, Arthit Chairoungdua
- Organizer
  Joint International Symposium Membrane Transport as a Universal Biological Mechanism
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2007-01-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Presentation] Involvement of transporters in nephrotoxicity.2006
- Author(s)
  Endou H, Anzai N
- Organizer
  15th World Congress of Pharmacology (IUPHAR)
- Place of Presentation
  Beijing, China
- Year and Date
  2006-07-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Presentation] Identification of the multivalent PDZ domain protein PDZKl as a binding partner of sodium-coupled monocarboxylate cotransporter 1 (SMCT1).2006
- Author(s)
  Naohiko Anzai, Hiroki Miyazaki, Xin He, Yoshikatsu Kanai, Seiji Miyauchi, Vadivel Ganapathy
- Organizer
  American Society of Nephrology Renal Week 2006
- Place of Presentation
  San Diego
- Year and Date
  2006-11-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590900
[Presentation] アミノ酸トランスポーター抑制よる抗腫瘍効果の検討2005
- Author(s)
  金井好克, 安西尚彦, Chairoungdua A, 遠藤仁
- Organizer
  第64回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2005-09-15
- Data Source
  KAKENHI-PROJECT-17081016
[Presentation] Molecular mechanism of urate-lowering effect of calcium channel blockers
- Author(s)
  土屋豪, 福田宏嗣, 安西尚彦, et al
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-25670600
[Presentation] スキルス胃癌細胞44As3－11におけるLAT1の発現現象による遺伝子発現変化の解析
- Author(s)
  林啓太朗、遠藤仁、安西尚彦
- Organizer
  日本癌学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] LAT1特異的阻害薬によるT細胞活性化の抑制
- Author(s)
  林啓太朗、遠藤仁、安西尚彦
- Organizer
  第41回日本臨床免疫学会総会
- Place of Presentation
  下関
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] Ca拮抗薬による尿酸降下作用の解析
- Author(s)
  土屋豪, 鬼澤信之, 堀貴行, Promsuk Jutabha, 大谷直由, 長谷川元, 福田宏嗣, 安西尚彦
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] 尿酸トランスポーター研究　最近の展開
- Author(s)
  安西尚彦, 大内基司, 大谷直由, Promsuk Jutabha
- Organizer
  第48回日本痛風・核酸代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2015-02-19 – 2015-02-20
- Data Source
  KAKENHI-PROJECT-23590647
[Presentation] Suppressive effects of LAT1-specific inhibitor on the activation of human T cells
- Author(s)
  林啓太朗、安西尚彦
- Organizer
  第7回次世代を担う医療薬科学シンポジウム（日本薬学会）
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 必須アミノ酸トランスポーターLAT1の特異的阻害薬によるヒトT細胞の活性化抑制
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  第124回　日本薬理学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] ヒトの尿酸代謝：オーバービュー
- Author(s)
  安西尚彦, 大内基司, 大谷直由, Promsuk Jutabha
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] ヒトスキルス胃癌におけるLAT1発現減少による遺伝子変化の解析
- Author(s)
  林啓太朗、遠藤仁、安西尚彦
- Organizer
  日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 癌胎児性中性アミノ酸トランスポーターLAT1の発現低下に伴う癌細胞の遺伝子発現変化
- Author(s)
  林啓太朗、遠藤仁、安西尚彦
- Organizer
  日本がん分子標的治療学会学術集会
- Place of Presentation
  北九州市
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 腎尿細管尿酸上皮輸送研究のための尿酸トランスポーター過剰発現マウスの解析
- Author(s)
  安西尚彦, Jutabha Promsuk, et al
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島市
- Data Source
  KAKENHI-PROJECT-23590647
[Presentation] T細胞活性化における必須アミノ酸トランスポーターLAT1の重要性
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  第10回　宮崎サイエンスキャンプ
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-24590328
[Presentation] 尿酸トランスポーター研究　最近の展開
- Author(s)
  安西尚彦, 大内基司, 大谷直由, Promsuk Jutabha
- Organizer
  第48回日本痛風・核酸代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2015-02-19 – 2015-02-20
- Invited
- Data Source
  KAKENHI-PROJECT-26461258
[Presentation] Ca拮抗薬による尿酸降下作用の解析
- Author(s)
  土屋豪, 鬼澤信之, 堀貴行, Promsuk Jutabha, 大谷直由, 長谷川元, 福田宏嗣, 安西尚彦
- Organizer
  日本高血圧学会総会
- Place of Presentation
  横浜
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-25670600
[Presentation] 癌胎児性中性アミノ酸トランスポーターLAT1特異的阻害薬によるT細胞活性化の抑制
- Author(s)
  林啓太朗、Promsuk Jutabha、遠藤仁、安西尚彦
- Organizer
  第129回　日本薬理学会関東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590328

1. KANAI Yoshikatsu (60204533)

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2. PROMSUK Jutabha (90541748)

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3. HOSOYAMADA Makoto (00291659)

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9. IRIBE Yuji (20348618)

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33. HORI TAKAYUKI

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34. OHNO YUTA

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36. NATSUME Tohru (00357683)

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40. SHINOHARA Yoshihiko (00154229)

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41. NAKAMURA Makiko (80447557)

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44. YAN Kunimasa (70255389)

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92. TSUKADA Ai

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94. NOHARA Masakatsu

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95. WAKASHIN Hidefumi

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96. KANO Yuji

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97. ONIZAWA Nobuyuki

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98. OTSUKA Yusuke

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100. AMMONPATUMRAT Sirirat

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101. THAMMAPRATIP Thanapol

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104. CHAIROUNGDUA A

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105. FUKUYO Masaki

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106. MATSUSAKA Keisuke

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112. 李佩俐

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Anzai Naohiko 安西 尚彦

ANZAI Naohiko 安西 尚彦

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Transporter-targeted drug development against urological cancers by utilizing liquid biopsy and AIPrincipal Investigator

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Development of new BNCT sensitizer based on molecular chirality recognition of amino acid transporter LATPrincipal Investigator

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New drug development targeting novel renal tubular rate transporter MCT9 based on the structure-activity relationshipPrincipal Investigator

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Anzai Naohiko 安西尚彦

ANZAI Naohiko 安西尚彦