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Morishita Soji  森下 総司

Researcher Number 10635866
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-1081-0130
Affiliation (Current) 2025: 順天堂大学, 医学部, 客員准教授
Affiliation (based on the past Project Information) *help 2023: 順天堂大学, 医学部, 客員准教授
2020 – 2023: 順天堂大学, 医学部, 特任助教
2013 – 2019: 順天堂大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Laboratory medicine / Basic Section 54010:Hematology and medical oncology-related
Except Principal Investigator
Hematology / Basic Section 54010:Hematology and medical oncology-related
Keywords
Principal Investigator
骨髄増殖性腫瘍 / 遺伝子変異検出 / 腫瘍マーカー / 巨核球 / 血小板 / 小胞体ストレス応答因子 / 1細胞解析技術 / 生細胞内イメージング / 予後因子 / 予後予測マーカー … More / 網羅的遺伝子変異解析 / ターゲットリシーケンシング / 骨髄増殖生腫瘍 / 骨髄線維症 / 予後不良因子 / JAK2V617F変異検出 / 次世代シークエンス / JAK2遺伝子 / 真性赤血球増加症 … More
Except Principal Investigator
骨髄増殖性腫瘍 / 癌 / 本態性血小板血症 / 診断マーカー / calreticulin / CALR / JAK2 / CD44 / 原発性骨髄線維症 / JAK2V617F / 転写因子 / 小胞体ストレス / 巨核球 / 血小板 / 小胞体ストレス応答因子 / ゲノム / 細胞 / 遺伝子 / 急性白血病 / 骨髄線維症 / ドライバー遺伝子 / 家族性骨髄増殖性腫瘍 / 網羅的遺伝子解析 / ゲノム編集 / iPS / CRISPR/Cas9 / JAK2V617F変異 / iPS細胞 / 核酸 / 内科 / 疾患マーカー / 血小板増多 / 網羅的遺伝子発現解析 / Calreticulin / thrombopoietin / MPL / トロンボポエチン / シグナル伝達 / 分子シャペロン / サイトカイン受容体 Less
  • Research Projects

    (8 results)
  • Research Products

    (78 results)
  • Co-Researchers

    (9 People)
  •  骨髄増殖性腫瘍における小胞体ストレス応答分子の細胞腫瘍性に及ぼす影響の解明Principal Investigator

    • Principal Investigator
      森下 総司
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Juntendo University
  •  骨髄増殖性腫瘍幹細胞におけるCD44を中心とする接着因子発現・機能の調節機構解明

    • Principal Investigator
      後藤 明彦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Tokyo Medical University
  •  Understanding the mechanism of cell tumorigenesis promoted by essential thrombocythemia specific transcriptional network

    • Principal Investigator
      Komatsu Norio
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Juntendo University
  •  Clarification of the pathogenesis of myeloproliferative neoplasms based on the identification of genetic factors in familial cases

    • Principal Investigator
      Komatsu Norio
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Juntendo University
  •  Elucidation of molecular mechanism of cytokie receptor activation by mutant CALR

    • Principal Investigator
      ARAKI MARITO
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Juntendo University
  •  Finding poor prognostic factors of myelofibrosis targeting tumor cell populationPrincipal Investigator

    • Principal Investigator
      Morishita Soji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Juntendo University
  •  Identification of promising marker(s) for essential thrombocythemia diagnosis by differential gene expression approach

    • Principal Investigator
      KOMATSU Norio
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Juntendo University
  •  Exploring novel JAK2 mutations for definitive diagnostics of polycythemia veraPrincipal Investigator

    • Principal Investigator
      Morishita Soji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Juntendo University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Patent

  • [Journal Article] Non-driver gene mutation analysis in a large cohort of polycythemia vera and essential thrombocythemia2023

    • Author(s)
      Morishita S, Hashimoto Y, Furuya C, Edahiro Y, Ochiai T, Shirane S, Inano T, Yasuda H, Ando M, Araki M, Komatsu N
    • Journal Title

      European Journal of Haematology

      Volume: 110 Issue: 2 Pages: 131-136

    • DOI

      10.1111/ejh.13882

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03715
  • [Journal Article] Reevaluation of cardiovascular risk factors for thrombotic events in 580 Japanese patients with essential thrombocythemia2023

    • Author(s)
      Furuya C, Hashimoto Y, Morishita S, Inano T, Ochiai T, Shirane S, Edahiro Y, Araki M, Ando M, Komatsu N
    • Journal Title

      Journal of Thrombosis and Thrombolysis

      Volume: 55 Pages: 263-272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03715
  • [Journal Article] Clinical features of acquired erythrocytosis: Low levels of serum erythropoietin in a subset of non‐neoplastic erythrocytosis patients2022

    • Author(s)
      Mori Yosuke、Araki Marito、Morishita Soji、Imai Misa、Edahiro Yoko、Ito Masafumi、Ochiai Tomonori、Shirane Shuichi、Hashimoto Yoshinori、Yasuda Hajime、Ando Jun、Ando Miki、Komatsu Norio
    • Journal Title

      Cancer Medicine

      Volume: 12 Issue: 2 Pages: 1079-1089

    • DOI

      10.1002/cam4.4958

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08376, KAKENHI-PROJECT-20H03715
  • [Journal Article] Clinical and biological relevance of CREB3L1 in Philadelphia chromosome-negative myeloproliferative neoplasms2022

    • Author(s)
      De Marchi Federico、Okuda Maho、Morishita Soji、Imai Misa、Baba Terumi、Horino Mei、Mori Yosuke、Furuya Chiho、Ogata Satoko、Yang Yinjie、Ando Jun、Ando Miki、Araki Marito、Komatsu Norio
    • Journal Title

      Leukemia Research

      Volume: 119 Pages: 106883-106883

    • DOI

      10.1016/j.leukres.2022.106883

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08376, KAKENHI-PROJECT-21K16275, KAKENHI-PROJECT-20H03715
  • [Journal Article] Diagnosis of essential thrombocythemia2021

    • Author(s)
      OCHIAI Tomonori、MORISHITA Soji、KOMATSU Norio
    • Journal Title

      Japanese Journal of Thrombosis and Hemostasis

      Volume: 32 Issue: 4 Pages: 370-375

    • DOI

      10.2491/jjsth.32.370

    • NAID

      130008080837

    • ISSN
      0915-7441, 1880-8808
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-20H03715
  • [Journal Article] CREB3L1 overexpression as a potential diagnostic marker of Philadelphia chromosome?negative myeloproliferative neoplasms2020

    • Author(s)
      Morishita Soji、Yasuda Hajime、Yamawaki Saya、Kawaji Hideya、Itoh Masayoshi、Edahiro Yoko、Imai Misa、Kogo Yasushi、Tsuneda Satoshi、Ohsaka Akimichi、Hayashizaki Yoshihide、Ito Masafumi、Araki Marito、Komatsu Norio
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 2 Pages: 884-892

    • DOI

      10.1111/cas.14763

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-19K17871, KAKENHI-PROJECT-20H03715, KAKENHI-PROJECT-18K08372, KAKENHI-PROJECT-19K08848
  • [Journal Article] Clinical and molecular features of patients with prefibrotic primary myelofibrosis previously diagnosed as having essential thrombocythemia in Japan2019

    • Author(s)
      Edahiro Yoko、Araki Marito、Inano Tadaaki、Ito Masafumi、Morishita Soji、Misawa Kyohei、Fukuda Yasutaka、Imai Misa、Ohsaka Akimichi、Komatsu Norio
    • Journal Title

      European Journal of Haematology

      Volume: 00 Issue: 6 Pages: 1-5

    • DOI

      10.1111/ejh.13236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19203, KAKENHI-PROJECT-19K08848, KAKENHI-PROJECT-19K17871
  • [Journal Article] Mutational subtypes of JAK2 and CALR correlate with different clinical features in Japanese patients with myeloproliferative neoplasms.2018

    • Author(s)
      Misawa K, Yasuda H, Araki M, Ochiai T, Morishita S, Shirane S, Edahiro Y, Gotoh A, Ohsaka A, Komatsu N.
    • Journal Title

      Int J Hematol

      Volume: 印刷中 Issue: 6 Pages: 673-680

    • DOI

      10.1007/s12185-018-2421-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-17H04211
  • [Journal Article] Skewed megakaryopoiesis in human induced pluripotent stem cell-derived haematopoietic progenitor cells harbouring calreticulin mutations2018

    • Author(s)
      Hiraku Takei, Yoko Edahiro, Shuichi Mano, Nami Masubuchi, Yoshihsa Mizukami, Misa Imai, Soji Morishita, Kyohei Misawa, Tomonori Ochiai, Satoshi Tsuneda, Hiroshi Endo, Sou Nakamura, Koji Eto, Akimichi Ohsaka, Marito Araki, Norio Komatsu
    • Journal Title

      British Journal of Haematology

      Volume: 印刷中 Issue: 6 Pages: 791-802

    • DOI

      10.1111/bjh.15266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16J11017, KAKENHI-PROJECT-18K06690, KAKENHI-PROJECT-17K16195, KAKENHI-PROJECT-18K16126, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-18H04164
  • [Journal Article] The 2014 BCSH criteria and the 2016 WHO criteria for essential thrombocythemia: A comparison in a large-scale cohort.2018

    • Author(s)
      Ochiai T, Yasuda H, Araki M, Misawa K, Morishita S, Nudejima M, Hironaka Y, Shirane S, Edahiro Y, Gotoh A, Ohsaka A, Komatsu N.
    • Journal Title

      Eur J Haematol

      Volume: 印刷中 Issue: 6 Pages: 544-549

    • DOI

      10.1111/ejh.13041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K19559, KAKENHI-PROJECT-18K06690
  • [Journal Article] Hmga2 collaborates with JAK2 V617F in the development of myeloproliferative neoplasms2017

    • Author(s)
      Ueda K, Ikeda K, Ikezoe T, Harada-Shirado K, Ogawa K, Hashimoto Y, Sano T, Ohkawara H, Kimura S, Shichishima-Nakamura A, Nakamura Y, Shikama Y, Mori T, Mason PJ, Bessler M, Morishita S, Komatsu N, Shide K, Shimoda K, Koide S, Aoyama K, Oshima M, Iwama Aand Takeishi Y.
    • Journal Title

      Blood Advances

      Volume: 1 Issue: 15 Pages: 1001-1015

    • DOI

      10.1182/bloodadvances.2017004457

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09852, KAKENHI-PROJECT-17H04210, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K09457, KAKENHI-PROJECT-15K09483, KAKENHI-PROJECT-15K09484, KAKENHI-PROJECT-16K19565, KAKENHI-PROJECT-16K19582, KAKENHI-PROJECT-17K19687
  • [Journal Article] The 2016 WHO diagnostic criteria for polycythemia vera renders an accurate diagnosis to a broader range of patients including masked polycythemia vera: Comparison with the 2008 WHO diagnostic criteria.2017

    • Author(s)
      Misawa K, Yasuda H, Araki M, Ochiai T, Morishita S, Nudejima M, Hironaka Y, Shirane S, Edahiro Y, Gotoh A, Ohsaka A, Komatsu N.
    • Journal Title

      Am J Hematol

      Volume: 92 Issue: 7

    • DOI

      10.1002/ajh.24752

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-16K09859, KAKENHI-PROJECT-17H04211, KAKENHI-PROJECT-15K19559
  • [Journal Article] 骨髄増殖性腫瘍を引き起こす変異型calreticulinによるTPO受容体の活性化.2016

    • Author(s)
      今井美沙, 荒木真理人, 森下総司, 小松則夫.
    • Journal Title

      血液内科

      Volume: 73 Pages: 789-793

    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Journal Article] 骨髄増殖性腫瘍の遺伝子変異 最近の知見.2016

    • Author(s)
      荒木真理人, 森下総司, 小松則夫.
    • Journal Title

      臨床血液.

      Volume: 57 Pages: 2526-2534

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Journal Article] Melting curve analysis after T allele enrichment (MelcaTle) as a highly sensitive and reliable method for detecting the JAK2V617F mutation.2015

    • Author(s)
      Morishita S, Takahashi K, Araki M, Hironaka Y, Sunami Y, Edahiro Y, Tsutsui M, Ohsaka A, Tsuneda S, Komatsu N.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 3 Pages: e0122003-e0122003

    • DOI

      10.1371/journal.pone.0122003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07972, KAKENHI-PROJECT-25860416, KAKENHI-PROJECT-26893264
  • [Journal Article] JAK2, CALR, and MPL mutation status in Japanese myeloproliferative neoplasms patients2015

    • Author(s)
      Shirane S, Araki M, Morishita S, Edahiro Y, Sunami Y, Hironaka Y, Noguchi M, Koike M, Ohsaka A, and Komatsu N
    • Journal Title

      Haematologica

      Volume: 100 Issue: 2 Pages: e46-e48

    • DOI

      10.3324/haematol.2014.115113

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25860416, KAKENHI-PROJECT-26893264
  • [Journal Article] Detection of MPLW515L/K mutations and determination of allele frequencies with a single-tube PCR assay2014

    • Author(s)
      Takei H, Morishita S, Araki M, Edahiro Y, Sunami Y, Hironaka Y, Noda N, Sekiguchi Y, Tsuneda S, Ohsaka A, and Komatsu N
    • Journal Title

      PLoS ONE

      Volume: 9 Issue: 8 Pages: e104958-e104958

    • DOI

      10.1371/journal.pone.0104958

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25860416, KAKENHI-PROJECT-26893264
  • [Journal Article] JAK2V617F mutation status and allele burden in classical Ph-negative myeloproliferative neoplasms in Japan2014

    • Author(s)
      EdahiroY, Morishita S, Takahashi K, Hironaka Y, Yahata Y, Sunami Y, Shirane S, Tsutsui M, Noguchi M, Koike M, Imai K, Noda N, Sekiguchi Y, Tsuneda S, Ohsaka A, Araki M, Komatsu N
    • Journal Title

      Int J Hematol

      Volume: 99(5) Issue: 5 Pages: 625-634

    • DOI

      10.1007/s12185-014-1567-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591407, KAKENHI-PROJECT-25860416, KAKENHI-PROJECT-26893264
  • [Patent] 骨髄増殖性腫瘍の診断2018

    • Inventor(s)
      森下総司,小松則夫,山脇紗耶,常田聡,川路英哉,伊藤昌可
    • Industrial Property Rights Holder
      森下総司,小松則夫,山脇紗耶,常田聡,川路英哉,伊藤昌可
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-078074
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-15K15368
  • [Patent] 骨髄増殖性腫瘍の診断2018

    • Inventor(s)
      森下総司, 小松則夫, 他
    • Industrial Property Rights Holder
      森下総司, 小松則夫, 他
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-078074
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Patent] 遺伝子変異の検出方法及びそれに用いる蛍光標識オリゴヌクレオチド2015

    • Inventor(s)
      山口 正裕,蔵田 信也,小松 則夫,森下 総司
    • Industrial Property Rights Holder
      山口 正裕,蔵田 信也,小松 則夫,森下 総司
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-03-31
    • Acquisition Date
      2015-10-02
    • Data Source
      KAKENHI-PROJECT-25860416
  • [Presentation] Hypertriglyceridemia is a strong risk factor for thrombosis in ET patients2022

    • Author(s)
      Chiho Furuya, Yoshinori Hashimoto, Soji Morishita, Miki Ando, Norio Komatsu
    • Organizer
      第84回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03715
  • [Presentation] Clinical relevance of CREB3L1 expression in Ph-negative MPN2022

    • Author(s)
      Soji Morishita, Federico De Marchi, Maho Okuda, Misa Imai, Terumi Baba, Yosuke Mori, Chiho Furuya, Satoko Ogata, Yinjie Yang, Jun Ando, Miki Ando, Marito Araki, Norio Komatsu
    • Organizer
      第84回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03715
  • [Presentation] The MPL mutation is a risk factor for thrombosis in addition to JAK2V617F mutation in ET patients2022

    • Author(s)
      Chiho Furuya, Yoshinori Hashimoto, Soji Morishita, Miki Ando, Norio Komatsu
    • Organizer
      第84回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03715
  • [Presentation] Specific expression of CREB3L1 in megakaryocyte in myeloproliferative neoplasms2021

    • Author(s)
      Okuda M,Araki M,Federico D,Morishita S,Imai M,Mori Y,Horino M,Ochiai T,Shirame S,Edahiro Y,Ando J,Komatsu N
    • Organizer
      第83回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20H03715
  • [Presentation] CREB3L1 Overexpresion Can Reliably Discriminate Ph-MPNs From Reactive Cases2020

    • Author(s)
      Soji Morishita, Hajime Yasuda, Saya Yamawaki, Hideya Kawaji, Masayoshi Itoh, Yoko Edahiro, Misa Imai, Yasushi Kogo, Satoshi Tsuneda, Akimichi Ohsaka, Yoshihide Hayashizaki, Marito Araki, and Norio Komatsu
    • Organizer
      The 63rd American Society of Hematology Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03715
  • [Presentation] CREB3L1 overexpression as a novel diagnostic marker of Philadelphia-negative myeloproliferative neoplasms2020

    • Author(s)
      Soji Morishita, Hajime Yasuda, Saya Yamawaki, Hideya Kawaji, Masayoshi Itoh, Yoko Edahiro, Misa Imai, Yasushi Kogo, Satoshi Tsuneda, Akimichi Ohsaka, Yoshihide Hayashizaki, Marito Araki, and Norio Komatsu
    • Organizer
      The 82nd Annual Meeting of Japanese Society of Hematology
    • Data Source
      KAKENHI-PROJECT-20H03715
  • [Presentation] 心筋梗塞・脳梗塞患者におけるJAK2 V617F変異の頻度.2019

    • Author(s)
      筒井深雪, 森下総司, 西野隆, 枝廣陽子, 常田聡, 荒木真理人, 大坂顯通, 小松則夫.
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] JAK2 V617Fのコピー数はサイトカイン受容体の活性化に重要である.2019

    • Author(s)
      北澤爽汰, 荒木真理人, 塩入香穂, 森下総司, 増渕菜弥, 馬場照美, 山本誠司, 堀内祥行, 今井美沙, 大坂顯通, 小松則夫.
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] JAK2アレルバーデンの高い患者は血小板コントロールが良好でもvWF活性低値のリスクが高い.2019

    • Author(s)
      飯塚和秀, 入山規良, 森下総司, 三浦勝浩, 飯塚芳一, 西崎祐史, 柳澤尚武, 安藤純, 内野慶人, 高橋宏通, 中川優, 濱田高志, 八田善弘, 中山智祥, 武井正美, 小松則夫.
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] The impact of allelic burden of JAK2V617F on human hematopoietic cell differentiation.2019

    • Author(s)
      枝廣陽子, 竹井拓, ChangLiu, 橳島麻衣, 森下総司, 大坂顯通, 荒木真理人, 小松則夫.
    • Organizer
      第29回日本サイトメトリー学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] 真性多血症患者由来iPS細胞におけるJAK2 V617F変異の修正.2019

    • Author(s)
      枝廣陽子, 劉暢, 荒木真理人, 橳島麻衣, 森下総司, 今井美沙, 増渕菜弥, 水上喜久, 眞野修一, 竹井拓, 大坂顯通, 小松則夫.
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] 非ドライバー変異と予後予測システムDIPSS/DIPSS-plus.2019

    • Author(s)
      森下総司, 落合友則, 三澤恭平, 大佐賀智, 稲野資明, 福田泰隆, 黒川安満, 枝廣陽子, 橳島麻衣, 緑川直子, 荒木真理人, 大坂顯通, 小松則夫.
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] 真正トリプルネガティブ本態性血小板血症における臨床的・分子生物学的特異性.2019

    • Author(s)
      稲野資明, 荒木真理人, 森下総司, 落合友則, 三澤恭平, 福田泰隆, 緑川直子, 橳島麻衣, 伊藤雅文, 大佐賀智, 枝廣陽子, 今井美沙, 田口鉄平, 奥田真帆, 大坂顯通, 小松則夫.
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] Mutations in epigenetic and splicing related genes among japanese overt and prefibrotic primary myelofibrosis using target sequencing.2019

    • Author(s)
      Morishita S, Ochiai T, Misawa K, Inano T, Fukuda Y, Kurokawa Y, Edahiro Y, Araki M, Ohsaka A, Komatsu N.
    • Organizer
      The 10th JSH INTERNATIONAL SYMPOSIUM
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] 腫瘍随伴性血管炎を合併した真性多血症.2019

    • Author(s)
      福田泰隆, 枝廣陽子, 森下総司, 筒井深雪, 新田英昭, 安藤純, 荒木真理人, 小松則夫.
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] Copy number of JAK2V617F modulates human hematopoietic cell differentiation.2018

    • Author(s)
      Edahiro Y, Mano S, Takei H, Li L, Morishita S, Gotoh A, Tsuneda S, Ohsaka A, Araki M, Komatsu N.
    • Organizer
      8th International Conference on Myeloproliferative Neoplasms
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] 受容体活性化において野生型JAK2は変異型JAK2を抑制しているようである.2018

    • Author(s)
      北澤爽汰, 荒木真理人, 森下総司, 楊印杰, 今井美沙, 大坂顕通, 小松則夫.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] ターゲット遺伝子シーケンスパネルによる原発性骨髄線維症の遺伝子変異解析.2018

    • Author(s)
      森下総司, 落合友則, 三澤恭平, 稲野資明, 橳島麻衣, 大坂顕道, 小松則夫.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] The Zygosity of JAK2V617F Determines the Disease Entities of Myeloproliferative Neoplasms By Modulating Erythropoiesis but Not Megakaryopoiesis.2018

    • Author(s)
      Takei H, Edahiro Y, Li L, Mizukami Y, Imai M, Morishita S, Ohsaka A, Araki M, Komatsu N.
    • Organizer
      ASH 60th Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] SLAMF7high CD16negative Monocytes Increase in Peripheral Blood of Patients with Myelofibrosis in Correlation with JAK2V617F Mutation2018

    • Author(s)
      Maekawa T, Kato S, Okada Y, Tachi N, Teramoto M, Kawamura T, Osawa Y, Kobayashi S, Sato K, Hashimoto M, Suzu S, Usuki K, Morishita S, Araki M, Komatsu N, Kimura F.
    • Organizer
      60th Annual Meeting & Exposition of American Society of Hematology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] APL細胞の分化誘導におけるATRA標的遺伝子の同定.2018

    • Author(s)
      角南義孝, 荒木真理人, 山本誠司, 堀内祥行, 辻岡一也, 薫 茂, 今井美沙, 森下総司, 大坂顯通, 小松則夫.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] トリプルネガティブ本態性血小板血症症例の臨床像と遺伝子変異.2018

    • Author(s)
      稲野資明, 荒木真理人, 福田泰隆, 森下総司, 落合友則, 三澤恭平, 伊藤雅文, 山本紘司, 楊印杰, 田口鉄平, 枝廣陽子, 今井美沙, 後藤明彦, 大坂顯通, 小松則夫.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] JAK2V617F変異アレル数はヒト血球分化を変化させる.2018

    • Author(s)
      竹井拓, 枝廣陽子, 李麗華, 水上喜久, 森下総司, 大坂顯通, 荒木真理人, 小松則夫.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] トリプルネガティブ本態性血小板血症症例の臨床像と遺伝子変異.2018

    • Author(s)
      稲野資明, 荒木真理人, 福田泰隆, 森下総司, 落合友則, 三澤恭平, 伊藤雅文, 山本紘司, 楊印杰, 田口鉄平, 枝廣陽子, 今井美沙, 後藤明彦, 大坂顯通, 小松則夫.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] 細胞減少療法はPMF患者における腎機能の悪化を防止する.2018

    • Author(s)
      福田泰隆, 荒木真理人, 山本紘司, 森下総司, 稲野資明, 三澤恭平, 落合友則, 枝廣陽子, 今井美沙, 後藤明彦, 大坂顯通, 小松則夫.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] 細胞減少療法はPMF患者における腎機能の悪化を防止する.2018

    • Author(s)
      福田泰隆, 荒木真理人, 山本紘司, 森下総司, 稲野資明, 三澤恭平, 落合友則, 枝廣陽子, 今井美沙, 後藤明彦, 大坂顯通, 小松則夫.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] 骨髄線維化を伴う骨髄異形成症候群の臨床病態および分子発症機序の解明.2018

    • Author(s)
      新谷直樹, 原田浩徳, 原田結花, 飯塚弘子, 森下総司, 荒木真理人, 大坂顯通, 土岐典子, 大橋一輝, 萩原政夫, 小松則夫.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] JAK2V617F変異アレル数はヒト血球分化を変化させる.2018

    • Author(s)
      竹井拓, 枝廣陽子, 李麗華, 水上喜久, 森下総司, 大坂顯通, 荒木真理人, 小松則夫.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] ターゲット遺伝子シーケンスパネルによる原発性骨髄線維症の遺伝子変異解析2018

    • Author(s)
      森下総司,落合友則,三澤恭平,稲野資明,ぬで島麻衣,大坂顯通,小松則夫
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K19203
  • [Presentation] The Zygosity of JAK2V617F Determines the Disease Entities of Myeloproliferative Neoplasms By Modulating Erythropoiesis but Not Megakaryopoiesis2018

    • Author(s)
      Takei H, Edahiro Y, Li L, Mizukami Y, Imai M, Morishita S, Ohsaka A, Araki M, Komatsu N.
    • Organizer
      60th Annual Meeting & Exposition of American Society of Hematology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] Copy number of JAK2V617F modulates human hematopoietic cell differentiation2018

    • Author(s)
      Edahiro Y, Mano S, Takei H, Morishita S, Tsuneda S, Ohsaka A, Araki M, Komatsu N.
    • Organizer
      8th International Conference on Myeloproliferative Neoplasms
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] Wild-type JAK2 may suppress mutant JAK2 activity in cytokine receptor activation.2018

    • Author(s)
      Kitazawa S, Araki M, Morishita S, Yang Y, Imai M, Ohsaka A, Komatsu N.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] 家族性骨髄増殖性腫瘍患者からの iPS細胞株の樹立.2017

    • Author(s)
      眞野修一, 竹井拓, 森下総司, 水上喜久, 増渕菜弥, 弘中由美, 橳島麻衣, 常田聡, 大坂顯通, 荒木真理人, 小松則夫.
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] Engagement of mutant calreticulin and MPL in a cellular compartment is required for MPL activation2017

    • Author(s)
      Nami Masubuchi, Marito Araki, Erina Hayashi, Yinjie Yang, Misa Imai Yoshihisa Mizukami, Yumi Hironaka, Hiraku Takei, Soji Morishita, Yoshihiko Kihara, Yoko Edahiro, Akimichi Ohsaka, Norio Komatsu
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] Mutant Calreticulin activates the thrombopoietin receptor in myeloproliferative neoplasms.2017

    • Author(s)
      Marito Araki, Yinjie Yang, Nami Masubuchi, Yoshihisa Mizukami, Misa Imai, Erina Hayashi, Yumi Hironaka, Soji Morishita, Yoko Edahiro, Akimichi Ohsaka, Norio Komatsu
    • Organizer
      The annual GAP Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] Establishment of an in vitro model for the skewed megakaryopoiesis by calreticulin mutation in human cells2017

    • Author(s)
      Hiraku Takei, Shuichi Mano, Nami Masubuchi, Yoshihisa Mizukami, Soji Morishita, Misa Imai, Yoko Edahiro, Yumi Hironaka, Mai Nudejima, Satoshi Tsuneda, Hiroshi Endo, Sou Nakamura, Koji Eto, Akimichi Ohsaka, Marito Araki, Norio Komatsu
    • Organizer
      22nd Congress of the European Hematology Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] カルレチキュリン変異を有する血球前駆細胞は巨核球への分化偏向性を有する.2017

    • Author(s)
      竹井拓, 眞野修一, 増渕菜弥, 水上喜久, 今井美沙, 森下総司, 枝廣陽子, 弘中由美, 橳島麻衣, 常田聡, 遠藤大, 中村壮, 江藤浩之, 大坂顯通, 荒木真理人, 小松則夫.
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] Establishment of an in vitro model for the skewed megakaryopoiesis by calreticulin mutation in human cells.2017

    • Author(s)
      Takei H, Mano S, Masubuchi N, Mizukami Y, Morishita S, Imai M, Edahiro Y, Hironaka Y, Nudejima M, Tsuneda S, Endo H, Nakamura S, Eto K, Ohsaka A, Araki M, Komatsu N.
    • Organizer
      22nd Congress of the European Hematology Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] 変異型 CALR による巨核球分化偏向性は GATA2 の発現亢進と相関している.2017

    • Author(s)
      竹井拓, 眞野修一, 増渕菜弥, 水上喜久, 今井美沙, 森下総司, 枝廣陽子, 弘中由美, 橳島麻衣, 遠藤大, 中村壮, 江藤浩之, 大坂顯通, 荒木真理人, 小松則夫.
    • Organizer
      第79回日本血液学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] Engagement of mutant calreticulin and MPL in a cellular compartment is required for MPL activation.2017

    • Author(s)
      Masubuchi N, Araki M, Hayashi E, Yang Y, Imai M, Mizukami Y, Hironaka Y, Takei H, Morishita S, Kihara Y, Edahiro Y, Ohsaka A, Komatsu N.
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] Skewed megakaryopoiesis by mutant calreticulin is associated with increased GATA2 expression2017

    • Author(s)
      Hiraku Takei, Shuichi Mano, Nami Masubuchi, Yoshihisa Mizukami, Misa Imai, Soji Morishita, Yoko Edahiro Yumi Hironaka Mai Nudejima Hiroshi Endo, Sou Nakamura, Koji Eto, Akimichi Ohsaka, Marito Araki, Norio Komatsu
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] BCR-JAK2 陽性骨髄増殖性腫瘍.2017

    • Author(s)
      筒井深雪, 後藤明彦, 森下総司, 荒木真理人, 福田泰隆, 新田英昭, 安藤純, 小松則夫.
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04211
  • [Presentation] Cell surface localization of mutant Calreticulin that induces myeloproliferative neoplasms (MPNs).2016

    • Author(s)
      Masubuchi N, Araki M, Yang Y, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Ohsaka A, Komatsu N.
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] 骨髄増殖生腫瘍を引き起こす変異型Calreticulinの細胞内局在2016

    • Author(s)
      増渕 菜弥, 荒木 真理人, Yinjie Yang, 弘中 由美, 竹井 拓, 森下 総司, 今井 美沙, 水上 喜久, Kan Shin、大坂 顯通, 小松 則夫.
    • Organizer
      第39回日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] Activation of the thrombopoietin receptor by mutant calreticulin in CALR-mutant myeloproliferative neoplasms.2016

    • Author(s)
      Araki M, Yang Y, Masubuchi N, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Shirane S, Edahiro Y, Sunami Y, Ohsaka A, Komatsu N.
    • Organizer
      21st Congress of the European Hematology Association.
    • Place of Presentation
      Copenhagen, Denmark
    • Year and Date
      2016-06-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] Mutant Calreticulin activates the thrombopoietin receptor in myeloproliferative neoplasms.2016

    • Author(s)
      Araki M, Yang Y, Masubuchi N, Hironaka Y, Takei H, Morishita S, Mizukami Y, Kan S, Shirane S, Edahiro Y, Sunami Y, Ohsaka A, Komatsu N.
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] Modeling MPN phenotypes in vitro by using iPSC harboring CALR ins5 mutation.2016

    • Author(s)
      Takei H, Masubuchi N, Mano S, Araki M, Morishita S, Mizukami Y, Kan S, Edahiro Y, Sunami Y, Hironaka Y, Endo H, Nakamura S, Eto K, Ohsaka A, Komatsu N.
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-16K09859
  • [Presentation] A interim analysis of stop trial against CMP-CP in CMR patients who had received sequential TKIs2015

    • Author(s)
      佐藤恵理子,森下総司,野口雅章,小池道明,大津洋,小松則夫
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      石川県金沢市
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25860416
  • [Presentation] Activation of AP-1 by JAK2V617F through induction and stabilization of c-FOS2015

    • Author(s)
      Edahiro Y, Araki M, Hironaka Y, Yang I, Morishita S, Sunami Y, Ohsaka A, and Komatsu N
    • Organizer
      The 57th ASH Annual Meeting
    • Place of Presentation
      Orlando, FL, USA
    • Year and Date
      2015-12-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25860416
  • [Presentation] Melting curve analysis after T allele enrichment: a highly sensitive and reliable method for detecting the JAK2V617F mutation2015

    • Author(s)
      Morishita S, Takahashi K, Araki M, Hironaka Y, Sunami Y, Edahiro Y, Tsutsui M, Ohsaka A, Tsuneda S, and Komatsu N
    • Organizer
      The 6th JSH International Symposium
    • Place of Presentation
      Nagano, Japan
    • Year and Date
      2015-05-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25860416
  • [Presentation] Early disease onset of patients with triple-negative myeloproliferative neoplasms2015

    • Author(s)
      白根脩一,荒木真理人,森下総司,枝廣陽子,竹井拓,津村真知子,弘中由美,落合友則,三澤恭平,大坂顯通,小松則夫
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      石川県金沢市
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25860416
  • [Presentation] Establishment of iPS cells from myeloproliferative neoplasms patients with CALR mutation2015

    • Author(s)
      竹井拓,森下総司,荒木真理人,水上喜久,枝廣陽子,角南義孝,弘中由美,津村真知子,常田聡,遠藤大,中村壮,江藤浩之,大坂顯通,小松則夫
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      石川県金沢市
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25860416
  • [Presentation] A highly specific method for detecting a single copy JAK2V617F mutation2015

    • Author(s)
      森下総司,荒木真理人,弘中由美,角南義孝,枝廣陽子,筒井深雪,大坂顯通,小松則夫
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      石川県金沢市
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-25860416
  • [Presentation] An epidemiologic study of classical Ph-negative myeloproliferative neoplasms (MPNs) in Japan2013

    • Author(s)
      Yoko Edahiro, Soji Morishita, Kochi Takahashi, Yoshitaka Sunami, Yuriko Yahata, Marito Araki, Satoshi Tsuneda, Akimichi Ohsaka, and Norio Komatsu
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-25860416
  • [Presentation] Establishment of a novel assay for MPLW515/K detection and allele burden measurement

    • Author(s)
      竹井拓,森下総司,荒木真理人,枝廣陽子,角南義孝,弘中由美,野田尚宏,関口勇地,常田聡,大坂顯通,小松則夫
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-31 – 2014-11-02
    • Data Source
      KAKENHI-PROJECT-25860416
  • [Presentation] MPL mutation analysis of Ph-negative myeloproliferative neoplasms in Japan

    • Author(s)
      枝廣陽子,白根脩一,竹井拓,森下総司,角南義孝,弘中由美,常田聡,大坂顯通,荒木真理人,小松則夫
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-10-31 – 2014-11-02
    • Data Source
      KAKENHI-PROJECT-25860416
  • [Presentation] Dynamic increase in JAK2V617F allele burden is a predictive parameter for the transformation into myelofibrosis from polycythemia vera and essential thrombocythosis

    • Author(s)
      Shirane S, Araki M, Morishita S, Hironaka Y, Noguchi M, Koike M, Hirano T, Ohsaka A, and Komatsu N
    • Organizer
      The 56th ASH Annual Meeting
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2014-12-06 – 2014-12-09
    • Data Source
      KAKENHI-PROJECT-25860416
  • 1.  KOMATSU Norio (50186798)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 58 results
  • 2.  ARAKI MARITO (80613843)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 52 results
  • 3.  今井 美沙 (50709003)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 4.  河合 純 (30391923)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  久野 敦 (50302287)
    # of Collaborated Projects: 1 results
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  • 6.  後藤 明彦 (00297293)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  高野 直治 (80445410)
    # of Collaborated Projects: 1 results
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  • 8.  ITO akihiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 9.  SHIDE Kotaro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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