Inomata Takenori 猪俣武範

Researcher Number	10645667
Other IDs
Affiliation (Current)	2023: 順天堂大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 順天堂大学, 医学部, 准教授 2019 – 2020: 順天堂大学, 医学部, 准教授 2016 – 2018: 順天堂大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56060:Ophthalmology-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Ophthalmology
Keywords	Principal Investigator 制御性T細胞 / 免疫寛容 / 角膜移植 / ドライアイ / 可塑性 / 不均一性 / マルチオミクス / 機械学習 / 眼免疫 / 血管新生 … More / ハイリスク角膜移植 / 角膜移植免疫 / 誘導性制御性T細胞 / GWAS / バイオバンク / モバイルヘルス / ゲノミクス / 免疫 / 多様性 / 炎症 / マルチオミクス機械学習 / RNAseq / マルチオミクス解析 / 移植免疫 / 拒絶反応 / 抗CD80/86抗体 / CTLA-4 / TGF-β / IL-10 / 内在性制御性T細胞 Less

モバイルヘルスとゲノミクスの融合によるドライアイの多様性理解と層別化医療の実現Principal Investigator
- Principal Investigator
  
  猪俣武範
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Juntendo University
マルチオミクス機械学習による制御性T細胞の可塑性と不均一性の解明Principal Investigator
- Principal Investigator
  
  猪俣武範
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Juntendo University
Multi-Omics Profiling of the Dry Eye Microenvironment to explore the Plasticity and Heterogeneity of Immune CellsPrincipal Investigator
- Principal Investigator
  
  猪俣武範
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Juntendo University
Development of a novel corneal transplant immunotolerance therapy using anti-CD80/86 antibody-induced regulatory T cellsPrincipal Investigator
- Principal Investigator
  
  Inomata Takenori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Juntendo University
New immunosuppressive therapy using a subset of regulatory T cellsPrincipal Investigator
- Principal Investigator
  
  Inomata Takenori
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Juntendo University

All 2021 2020 2018 2017 2016

All Journal Article Presentation

[Journal Article] Heterogeneity of eye drop use among symptomatic dry eye individuals in Japan: large-scale crowdsourced research using DryEyeRhythm application2021
- Author(s)
  Eguchi Atsuko、Inomata Takenori、Nakamura Masahiro、Nagino Ken、Iwagami Masao、Sung Jaemyoung、Midorikawa-Inomata Akie、Okumura Yuichi、Fujio Kenta、Fujimoto Keiichi、Miura Maria、Akasaki Yasutsugu、Shokirova Hurramhon、Hirosawa Kunihiko、Kuwahara Mizu、Zhu Jun、Dana Reza、Murakami Akira、Kobayashi Hiroyuki
- Journal Title
  
  Japanese Journal of Ophthalmology
  
  Volume: 65 Issue: 2 Pages: 271-281
- DOI
  10.1007/s10384-020-00798-1
- Data Source
  KAKENHI-PROJECT-20K23168, KAKENHI-PROJECT-20KK0207
[Journal Article] Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation2021
- Author(s)
  Shokirova Hurramhon、Inomata Takenori、Saitoh Tsuyoshi、Zhu Jun、Fujio Kenta、Okumura Yuichi、Yanagawa Ai、Fujimoto Keiichi、Sung Jaemyoung、Eguchi Atsuko、Miura Maria、Nagino Ken、Hirosawa Kunihiko、Kuwahara Mizu、Akasaki Yasutsugu、Nagase Hiroshi、Murakami Akira
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-88118-6
- Data Source
  KAKENHI-PROJECT-20K09810
[Journal Article] Novel immunotherapeutic effects of topically administered ripasudil (K-115) on corneal allograft survival2020
- Author(s)
  Inomata Takenori、Fujimoto Keiichi、Okumura Yuichi、Zhu Jun、Fujio Kenta、Shokirova Hurramhon、Miura Maria、Okano Mikiko、Funaki Toshinari、Sung Jaemyoung、Negishi Naoko、Murakami Akira
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 19817-19817
- DOI
  10.1038/s41598-020-76882-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09810, KAKENHI-PROJECT-19K18041
[Journal Article] Variable Responses to Corneal Grafts: Insights from Immunology and Systems Biology2020
- Author(s)
  Di Zazzo Antonio、Lee Sang-Mok、Sung Jaemyoung、Niutta Matteo、Coassin Marco、Mashaghi Alireza、Inomata Takenori
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 2 Pages: 586-586
- DOI
  10.3390/jcm9020586
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09810, KAKENHI-PROJECT-20KK0207, KAKENHI-PROJECT-18K16935
[Journal Article] Using Medical Big Data to Develop Personalized Medicine for Dry Eye Disease2020
- Author(s)
  Inomata Takenori、Sung Jaemyoung、Nakamura Masahiro、Iwagami Masao、Okumura Yuichi、Iwata Nanami、Midorikawa-Inomata Akie、Fujimoto Keiichi、Eguchi Atsuko、Nagino Ken、Fujio Kenta、Miura Maria、Shokirova Hurramhon、Murakami Akira
- Journal Title
  
  Cornea
  
  Volume: 39 Issue: 1 Pages: S39-S46
- DOI
  10.1097/ico.0000000000002500
- Data Source
  KAKENHI-PROJECT-20KK0207
[Journal Article] The immunoregulatory role of corneal epithelium-derived thrombospondin-1 in dry eye disease2018
- Author(s)
  Tan Xuhua、Chen Yihe、Foulsham William、Amouzegar Afsaneh、Inomata Takenori、Liu Yizhi、Chauhan Sunil K.、Dana Reza
- Journal Title
  
  The Ocular Surface
  
  Volume: 16 Issue: 4 Pages: 470-477
- DOI
  10.1016/j.jtos.2018.07.005
- Data Source
  KAKENHI-PROJECT-18K16935
[Journal Article] Method for selective quantification of immune and inflammatory cells in the cornea using flow cytometry2018
- Author(s)
  Ogawa Mamoru、Inomata Takenori、Shiang Tina、Tsubota Kazuo、Murakami Akira
- Journal Title
  
  Journal of Biological Methods
  
  Volume: 5 Issue: 4 Pages: e102-e102
- DOI
  10.14440/jbm.2018.237
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16935
[Journal Article] Pathological conversion of regulatory T cells is associated with loss of allotolerance2018
- Author(s)
  Hua Jing、Inomata Takenori、Chen Yihe、Foulsham William、Stevenson William、Shiang Tina、Bluestone Jeffrey A.、Dana Reza
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 7059-7059
- DOI
  10.1038/s41598-018-25384-x
- Data Source
  KAKENHI-PROJECT-18K16935
[Journal Article] Regulatory T Cell Modulation of Cytokine and Cellular Networks in Corneal Graft Rejection2018
- Author(s)
  Tahvildari Maryam、Inomata Takenori、Amouzegar Afsaneh、Dana Reza
- Journal Title
  
  Current Ophthalmology Reports
  
  Volume: 6 Issue: 4 Pages: 266-274
- DOI
  10.1007/s40135-018-0191-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16935
[Journal Article] Kinetics of Angiogenic Responses in Corneal Transplantation.2017
- Author(s)
  Inomata T, Mashaghi A, Di Zazzo A, Lee SM, Chiang H, Dana R.
- Journal Title
  
  Cornea
  
  Volume: 36(4) Issue: 4 Pages: 491-496
- DOI
  10.1097/ico.0000000000001127
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20332
[Journal Article] A New Immunotherapy Using Regulatory T-Cells for High-Risk Corneal Transplantation2017
- Author(s)
  Inomata T
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 63 Issue: 1 Pages: 2-7
- DOI
  10.14789/jmj.63.2
- NAID
  130006945293
- ISSN
  2187-9737, 2188-2126
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20332
[Presentation] Inhibitory effect of kappa opioid receptor agonist on corneal neovascularization2021
- Author(s)
  ショキロワフラムホン, 猪俣武範, 長瀬博, 斉藤毅, 藤尾謙太, 奥村雄一, 村上晶
- Organizer
  角膜カンファランス2021
- Data Source
  KAKENHI-PROJECT-20K09810
[Presentation] Ex vivo-induced bone marrow-derived myeloid suppressor cells prevent corneal allograft rejection in mice2021
- Author(s)
  Zhu Jun, Takenori Inomata, Keiichi Fujimoto, Koichiro Uchida, Kenta Fujio, Ken Nagino, Maria Miura, Naoko Negishi, Yuichi Okumura, Yasutsugu Akasaki, Kunihiko Hirosawa, Mizu Kuwahara, Atsuko Eguchi, Shokirova Hurramhon, Ai Yanagawa, Akira Murakami
- Organizer
  角膜カンファランス2021
- Data Source
  KAKENHI-PROJECT-20K09810
[Presentation] Multi-Omics Profiling for the Plasticity and Heterogeneity of Regulatory T Cells in corneal transplantation2021
- Author(s)
  Takenori Inomata
- Organizer
  第125回日本眼科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09810
[Presentation] Immunotherapeutic effects of ripasudil on corneal allograft survival2021
- Author(s)
  Takenori Inomata
- Organizer
  The 7th Asia Cornea Society Biennial Scientific Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09810
[Presentation] Blockade of CD80/86 prolongs corneal allograft survival2020
- Author(s)
  Okumura Y, Inomata T, Fujimoto K, Uchida K, Shiang T, Murakami A
- Organizer
  Gordon Research Conference on Cornea and Ocular Surface Biology and Pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16935
[Presentation] Blockade of CD80/86 prolongs corneal allograft survival2020
- Author(s)
  Yuichi Okumura, Takenori Inomata, Keiichi Fujimoto, Koichiro Uchida, Tina Shiang, Akira Murakami
- Organizer
  Gordon Research Conference on Cornea and Ocular Surface Biology and Pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16935
[Presentation] 制御性T細胞を用いた角膜移植における新規免疫抑制療法開発のための研究2018
- Author(s)
  猪俣武範
- Organizer
  角膜カンファランス2018
- Invited
- Data Source
  KAKENHI-PROJECT-16K20332
[Presentation] 制御性T細胞を用いた角膜移植における新規免疫抑制療法開発のための研究2018
- Author(s)
  猪俣　武範
- Organizer
  角膜カンファランス2018
- Invited
- Data Source
  KAKENHI-PROJECT-18K16935
[Presentation] The effect of Anti-CD80/86 antibody on regulatory T cells in murine corneal transplantation2018
- Author(s)
  Keiichi Fujimoto, Takenori Inomata, Koichiro Uchida, Tina Shiang, Yuichi Okumura, Akira Murakami
- Organizer
  ARVO 2018 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16935
[Presentation] 抗CD80/86抗体のマウス角膜移植における制御性T細胞への影響の検討2018
- Author(s)
  藤本啓一、猪俣武範、内田浩一郎、奥村雄一、村上晶
- Organizer
  第122回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-18K16935
[Presentation] 抗CD80/86抗体の角膜移植における免疫学的効果の検討2018
- Author(s)
  藤本啓一, 猪俣武範, 内田浩一郎, Tina Shiang, 村上晶
- Organizer
  角膜カンファランス2018
- Data Source
  KAKENHI-PROJECT-18K16935
[Presentation] 角膜移植における新規免疫抑制療法と血管新生抑制療法2017
- Author(s)
  猪俣武範
- Organizer
  2017年度応用薬理学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K20332
[Presentation] IMPAIRED FUNCTION OF PERIPHERALLY INDUCED REGULATORY T CELLS IN HOSTS OF HIGH RISK OF GRAFT REJECTION2016
- Author(s)
  Takenori Inomata, Jing Hua, Antonio Di Zazzo,and Reza Dana.
- Organizer
  Tear Film & Ocular Surface Society (TFOS) 2016
- Place of Presentation
  the Corum, Montpellier, France
- Year and Date
  2016-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20332
[Presentation] Kinetics of Angiogenic Responses in High-Risk Corneal Transplantation2016
- Author(s)
  Takenori Inomata, Alireza Mashaghi, Antonio Di Zazzo, Sang-Mok Lee, Chiang Homer and Reza Dana
- Organizer
  第16回日本抗加齢医学会総会
- Place of Presentation
  パシフィコ横浜会議センター、神奈川県、横浜
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-16K20332
[Presentation] ハイリスク角膜移植に対する制御性T細胞のサブセットを用いた新規免疫抑制療法開発のための研究2016
- Author(s)
  岡野美樹子, 猪俣武範, 村上晶
- Organizer
  第36回日本眼薬理学会
- Place of Presentation
  帝京大学板橋キャンパス、東京都、板橋区
- Invited
- Data Source
  KAKENHI-PROJECT-16K20332

1. 中村正裕 (40634449)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. 藤本啓一 (10876684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 布施昇男 (10302134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 清水厚志 (30327655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 猪俣明恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Inomata Takenori 猪俣 武範

Research Projects

Research Products

Co-Researchers

モバイルヘルスとゲノミクスの融合によるドライアイの多様性理解と層別化医療の実現Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マルチオミクス機械学習による制御性T細胞の可塑性と不均一性の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Multi-Omics Profiling of the Dry Eye Microenvironment to explore the Plasticity and Heterogeneity of Immune CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel corneal transplant immunotolerance therapy using anti-CD80/86 antibody-induced regulatory T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New immunosuppressive therapy using a subset of regulatory T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Heterogeneity of eye drop use among symptomatic dry eye individuals in Japan: large-scale crowdsourced research using DryEyeRhythm application2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel immunotherapeutic effects of topically administered ripasudil (K-115) on corneal allograft survival2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Variable Responses to Corneal Grafts: Insights from Immunology and Systems Biology2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Using Medical Big Data to Develop Personalized Medicine for Dry Eye Disease2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The immunoregulatory role of corneal epithelium-derived thrombospondin-1 in dry eye disease2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Method for selective quantification of immune and inflammatory cells in the cornea using flow cytometry2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathological conversion of regulatory T cells is associated with loss of allotolerance2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulatory T Cell Modulation of Cytokine and Cellular Networks in Corneal Graft Rejection2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kinetics of Angiogenic Responses in Corneal Transplantation.2017

Inomata Takenori 猪俣武範