shida yasuaki 志田泰明

Researcher Number	10721566
Affiliation (based on the past Project Information) *help	2019: 奈良県立医科大学, 医学部, 研究員 2014 – 2018: 奈良県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Pediatrics
Keywords	Principal Investigator 血管内皮細胞 / 血流 / 内科 / 蛋白質 / 生理学 / von Willebrand 因子 / 第VIII因子 / shear stress / 血管内皮 / FVIII … More / 凝固因子 / 血栓止血 / 血液 / フォン･ヴィレブランド病 / ヴォン･ヴィレブランド病 / 血友病 / 血栓 / 凝固 / ずり応力 Less

The response of endothelial cells and the function of coagulation factor VIII under flow conditionsPrincipal Investigator
- Principal Investigator
  
  Shida Yasuaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nara Medical University
Regulation of the function of endothelial cells by shear stressPrincipal Investigator
- Principal Investigator
  
  shida yasuaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nara Medical University

All 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book

[Book] 血液疾患診療ハンドブック　診療の手引と臨床データ集2015
- Author(s)
  志田泰明, 嶋緑倫
- Total Pages
  591
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-26461593
[Book] 新血栓止血血管学2015
- Author(s)
  志田泰明, 嶋緑倫
- Total Pages
  189
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-26461593
[Book] 内科医･小児科医研修医のための小児救急治療ガイドライン2015
- Author(s)
  志田泰明, 嶋緑倫
- Total Pages
  520
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-26461593
[Book] 小児救急治療ガイドライン2015
- Author(s)
  志田泰明, 嶋緑倫
- Total Pages
  524
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-26461593
[Book] 内科外来処方NAVI2014
- Author(s)
  志田泰明, 嶋緑倫
- Total Pages
  224
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-26461593
[Journal Article] Global coagulation function assessed by rotational thromboelastometrypredicts coagulation-steady state in individual hemophilia A patients receiving emicizumab prophylaxis.2019
- Author(s)
  Yada K , Nogami K, Ogiwara K, Shida Y, Furukawa S, Yaoi H, Takeyama M, Kasai R,Shima M.
- Journal Title
  
  International Journal of Haematology
  
  Volume: 110(4) Issue: 4 Pages: 419-430
- DOI
  10.1007/s12185-019-02698-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07798, KAKENHI-PROJECT-17K10125, KAKENHI-PROJECT-17K10126
[Journal Article] Shear stress and platelet-induced tensile forces regulate ADAMTS13-localization within the platelet thrombus.2019
- Author(s)
  Shida Y, Swystun LL, Brown C, Mewburn J, Nesbitt K, Danisment O, Riches JJ, Hough C, Lillicrap D.
- Journal Title
  
  Res Pract Thromb Haemost.
  
  Volume: 2 Issue: 2 Pages: 254-260
- DOI
  10.1002/rth2.12196
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10126
[Journal Article] Factor (F)VIII/VIIa enhances global haemostatic function in the co-presence of bypassing agents and FVIII among patients with haemophilia A with inhibitor2018
- Author(s)
  Nogami K, Matsumoto T, Yada K, Ogiwara K, Furukawa S, Shida Y, Takeyama M, Shima M
- Journal Title
  
  Br J Haematol
  
  Volume: ahead of printing Issue: 4 Pages: 528-536
- DOI
  10.1111/bjh.15209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10126, KAKENHI-PROJECT-17H04231, KAKENHI-PROJECT-15K09663, KAKENHI-PROJECT-15K09664, KAKENHI-PROJECT-17K10127, KAKENHI-PROJECT-18K07798, KAKENHI-PROJECT-18K07885
[Journal Article] A case of moderate haemophilia A with inhibitor, carrying the p.R1800H mutation, complicated with juvenile idiopathic arthritis2018
- Author(s)
  Yuka Kondo Yasuaki Shida Tomoaki Ishikawa Koji Yada Masahiro Takeyama Midori Shima Keiji Nogami
- Journal Title
  
  Haemophilia
  
  Volume: 25(1) Issue: 1 Pages: 51-54
- DOI
  10.1111/hae.13648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10126, KAKENHI-PROJECT-17K10125
[Journal Article] Role of red blood cells in the anemia-associated bleeding under high shear conditions2017
- Author(s)
  H. Yaoi, Y. Shida,, K. Ogiwara, K. Hosokawa, M. Shima and K. Nogami
- Journal Title
  
  hemophilia
  
  Volume: - Issue: 5 Pages: 750-758
- DOI
  10.1111/hae.13252
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461593, KAKENHI-PROJECT-17K10126
[Journal Article] Highly elevated plasma level of von Willebrand factor accelerates the formation of platelet thrombus under high shear stress in plasma with deficient ADAMTS13 activity.2017
- Author(s)
  Yagi H, Yamaguchi N, Shida Y, Sugimoto M, Tubaki K, Fujimura Y, Matsumoto M
- Journal Title
  
  Thromb Res
  
  Volume: 159 Pages: 91-95
- DOI
  10.1016/j.thromres.2017.10.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10126
[Journal Article] Successful haemostatic management of replacement of the ascending aorta for type A acute aortic dissection in a patient with mild haemophilia B2016
- Author(s)
  Takeyama M, Nogami K, Shida Y, Yada K, Hirose T, Hayata Y, Tabayashi N, Taniguchi S, Akasaki Y, Kawaraguchi Y, Kawaguchi M, Shima M
- Journal Title
  
  Haemophilia
  
  Volume: Jan 29 Issue: 2
- DOI
  10.1111/hae.12879
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461593
[Journal Article] Assessing the clinical severity of type 1 von Willebrand disease patients with a microchip flow-chamber system.2016
- Author(s)
  Nogami K1, Ogiwara K1, Yada K1, Shida Y1, Takeyama, Yaoi　H, Minami H, Furukawa S, Hosokawa K, Shima M
- Journal Title
  
  J Thromb Haemost
  
  Volume: 14 Issue: 4 Pages: 667-74
- DOI
  10.1111/jth.13273
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461593
[Journal Article] The utility of VWF multimer analysis in response to the desmopressin administration for the diagnosis of severe type 1 von Willebrand disease.2016
- Author(s)
  Takeyama M, Nogami K, Onaka M, Yada K, Shida Y, Shima M
- Journal Title
  
  Haemophilia
  
  Volume: Jan 29 Issue: 2
- DOI
  10.1111/hae.12874
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461593
[Journal Article] Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation2015
- Author(s)
  1)Shida Y, Rydz N, Stegner D, Brown C , Mewburn J, Sponagle K , Danisment Ozge, Crawford B, Vidal B, Hegadorn C, Pruss C, Nieswandt B and Lillicrap D
- Journal Title
  
  Blood
  
  Volume: 124(11) Issue: 11 Pages: 1799-1807
- DOI
  10.1182/blood-2013-09-521484
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461593
[Journal Article] FVIIIの生合成およびフォン･ヴィレブランド因子との相互作用に関する最新の知見2015
- Author(s)
  志田　泰明,　野上恵嗣
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 26（1） Pages: 49-56
- NAID
  130004847363
- Open Access
- Data Source
  KAKENHI-PROJECT-26461593
[Journal Article] フォン・ヴィレブランド病の病態と診療2015
- Author(s)
  志田　泰明,　野上恵嗣
- Journal Title
  
  日本小児血液・がん学会雑誌
  
  Volume: 52（1） Pages: 1-9
- NAID
  40020456048
- Open Access
- Data Source
  KAKENHI-PROJECT-26461593
[Journal Article] フォン･ヴィレブランド病の分子生物学的診断と診療への応用2014
- Author(s)
  志田　泰明,　野上恵嗣
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 25(4)
- NAID
  130004687765
- Open Access
- Data Source
  KAKENHI-PROJECT-26461593
[Presentation] Impaired thrombus formation of von Willebrand Disease under high shear flow condition is improved by factor FVIIIa mimetic bispecific antibody(emicizumab)2018
- Author(s)
  Hiroaki Yaoi, Yasuaki Shida, Keiji Nogami, Takehisa Kitazawa, Midori Shima
- Organizer
  world federation of hemophilia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10126
[Presentation] VWD 各病型におけるEmicizumab の高ずり応力下での止血効果2018
- Author(s)
  矢追博章，志田泰明，野上恵嗣，北沢剛久，嶋緑倫
- Organizer
  第40回　日本血栓止血学会
- Data Source
  KAKENHI-PROJECT-17K10126
[Presentation] FVIIIa Mimicking Bispecific Antibody (emicizumab) Improved Thrombus Formation of Type 2N von Willebrand Disease under Both High and Low Shear Conditions2017
- Author(s)
  Hiroaki Yaoi, Yasuaki Shida, Takehisa Kitazawa、Kunihiro Hattori, Midori Shima, Keiji Nogami
- Organizer
  International society of thrombosis and haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10126
[Presentation] Factor VIIIa mimetic bispecific antibody (emicizumab) improves thrombus formation of von Willebrand disease under high shear flow condition2017
- Author(s)
  Yasuaki Shida, Hiroaki Yaoi, Takehisa Kitazawa、Kunihiro Hattori, Midori Shima, Keiji Nogami
- Organizer
  East Asia hemophilia forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10126
[Presentation] Activated FVIII Released From FVIII/VWF Complex Facilitates Thrombus Development Under Flow Condition2017
- Author(s)
  Hiroaki Yaoi, Yasuaki Shida, Takehisa Kitazawa、Kunihiro Hattori, Midori Shima, Keiji Nogami
- Organizer
  East Asia hemophilia forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10126
[Presentation] 抗FIXa/FX-bispecific抗体（Emicizumab）のType2N von Willebrand病での血流下血栓形成能の改善効果2017
- Author(s)
  矢追博章、志田泰明、野上恵嗣、北沢剛久、服部有宏、嶋　緑倫
- Organizer
  第39回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10126
[Presentation] Activated FVIII Released From FVIII/VWF Complex Facilitates Thrombus Development Under Flow Condition2016
- Author(s)
  Hiroaki Yaoi, Yasuaki Shida, Takehisa Kitazawa, Kunihiro Hattori, Midori Shima, Keiji Nogami
- Organizer
  American society of hematology
- Place of Presentation
  San Diego
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461593
[Presentation] Impact of FVIIIa mimicking antibody, emicizumab, on shear dependent thrombus formation2016
- Author(s)
  Hiroaki Yaoi, Yasuaki Shida, Takehisa Kitazawa, Kunihiro Hattori, Midori Shima, Keiji Nogami
- Organizer
  Japanese society of hematology
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-26461593
[Presentation] 血流下血栓形成過程における第Ⅷ因子代替バイスペシフィック抗体ACE910の作用機序2015
- Author(s)
  矢追博章、志田泰明、野上恵嗣、南博明、北沢剛久、服部有宏、嶋　緑倫
- Organizer
  第37回血栓止血学会
- Place of Presentation
  甲府
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-26461593
[Presentation] The impact of red blood cells on hemostasis under whole blood flow conditions2015
- Author(s)
  Yaoi H., Shida Y., Nogami K., Minami H., Matsumoto T, Ogiwara K., Hosokawa K.， Shima M
- Organizer
  25th International Society of Thrombosis and Hemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-26461593
[Presentation] A case of moderate hemophilia A with p.R1800H mutation complicated with juvenile idiopathic arthritis2015
- Author(s)
  Shida Y., Kondo Y., Ishikawa T., Yada K., Takeyama M., Nogami K., Shima M
- Organizer
  25th International Society of Thrombosis and Hemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461593
[Presentation] 全血流動システムによって示される赤血球のずり速度依存性止血効果2015
- Author(s)
  矢追　博章, 志田　泰明, 野上　恵嗣, 松本　智子, 荻原　建一, 細川　和也, 嶋　緑倫
- Organizer
  第77回日本血液学会
- Place of Presentation
  金沢
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-26461593
[Presentation] The impact of Total-Thrombus Analysis System in the management of VWD with severe anemia2014
- Author(s)
  Shida Y., Nogami K., Minami H., Yada K., Takeyama M., Matsumoto T., Ogiwara K., Shima M.
- Organizer
  日本血液学会
- Place of Presentation
  大阪
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-26461593
[Presentation] Distinct localization of coagulation factor VIII, von Willebrand factor and factor VIII-mimetic bispecific antibody contributing to thrombus formation under whole blood flow conditions2014
- Author(s)
  Shida Y., Nogami K., Minami H., Yaoi H., Matsumoto T., Kitazawa T., Hattori K., Shima M
- Organizer
  American Society of Hematology
- Place of Presentation
  サンフランシスコ
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-26461593
[Presentation] Comprehensive characterization of loss and gain-of-function von Willebrand factor collagen binding variants and the role of GPVI using a mouse model system2014
- Author(s)
  Shida Y., Lillicrap D, Shima M.
- Organizer
  日本血栓止血学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-31
- Data Source
  KAKENHI-PROJECT-26461593

1. 野上恵嗣 (50326328)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
2. 矢田弘史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

shida yasuaki 志田 泰明

Research Projects

Research Products

Co-Researchers

The response of endothelial cells and the function of coagulation factor VIII under flow conditionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of the function of endothelial cells by shear stressPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 血液疾患診療ハンドブック 診療の手引と臨床データ集2015

Author(s)

Total Pages

Publisher

Data Source

[Book] 新血栓止血血管学2015

Author(s)

Total Pages

Publisher

Data Source

[Book] 内科医･小児科医研修医のための小児救急治療ガイドライン2015

Author(s)

Total Pages

Publisher

Data Source

[Book] 小児救急治療ガイドライン2015

Author(s)

Total Pages

Publisher

Data Source

[Book] 内科外来処方NAVI2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Global coagulation function assessed by rotational thromboelastometrypredicts coagulation-steady state in individual hemophilia A patients receiving emicizumab prophylaxis.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Shear stress and platelet-induced tensile forces regulate ADAMTS13-localization within the platelet thrombus.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Factor (F)VIII/VIIa enhances global haemostatic function in the co-presence of bypassing agents and FVIII among patients with haemophilia A with inhibitor2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case of moderate haemophilia A with inhibitor, carrying the p.R1800H mutation, complicated with juvenile idiopathic arthritis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of red blood cells in the anemia-associated bleeding under high shear conditions2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Highly elevated plasma level of von Willebrand factor accelerates the formation of platelet thrombus under high shear stress in plasma with deficient ADAMTS13 activity.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Successful haemostatic management of replacement of the ascending aorta for type A acute aortic dissection in a patient with mild haemophilia B2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Assessing the clinical severity of type 1 von Willebrand disease patients with a microchip flow-chamber system.2016

Author(s)

Journal Title

DOI

shida yasuaki 志田泰明

[Book] 血液疾患診療ハンドブック　診療の手引と臨床データ集2015