ODA Shingo 織田進吾

Researcher Number	10725534
Other IDs
Affiliation (Current)	2021: 名古屋大学, 医学系研究科, 特任助教
Affiliation (based on the past Project Information) *help	2016 – 2020: 名古屋大学, 医学系研究科, 特任助教 2016 – 2017: 名古屋大学, 医学系研究科, 助教 2015: 名古屋大学, 医学(系)研究科(研究院), 特任助教 2014: 名古屋大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Medical pharmacy / Pharmacology in pharmacy / Basic Section 47040:Pharmacology-related Except Principal Investigator Applied pharmacology / Medical pharmacy / Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator 肝障害 / 薬物性肝障害 / 薬物代謝 / in vitroアッセイ / 免疫 / 炎症 / 炎症反応 / 細胞アッセイ / 薬剤性肝障害 / DILI … More Except Principal Investigator 薬物性肝障害 / 合成カチノン / 危険ドラッグ / ドーパミン / セロトニン / 神経毒性 / 肝障害予測 / 医薬品開発 / マイクロRNA / 特異体質性肝障害 / バイオマーカー / 動物モデル / 肝類洞内皮細胞 / microRNA / 薬物性腎障害 / 毒性発現機序解析 / 毒性発現予測試験系 / グルタチオン / ラモトリギン / エナラプリル / in vitro cell-based スクリーニング / 酸化ストレス / 毒性発現機序 / 血中マイクロRNA / 薬剤反応性 / 薬学 / 細胞・組織 / 炎症免疫因子 / 特異体質性 / 発症機序 / 前臨床医薬品開発 / エクソソーム / 免疫因子 / 非実質細胞 Less

特異体質性薬物性肝障害発症の個体差の決定因子の解明と予測試験系の開発Ongoing
- Principal Investigator
  
  横井毅
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Nagoya University
Comprehensive functional analysis of lncRNAs in liver fibrosisPrincipal Investigator
- Principal Investigator
  
  織田進吾
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Nagoya University
Establishment of animal models and treatment methods for drug-induced rhabdomyolysisPrincipal Investigator
- Principal Investigator
  
  Oda Shingo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya University
Establishment of a predictive test system for idiosyncratic drug-induced liver injury and study for evaluation of onset biomarkers
- Principal Investigator
  
  Yokoi Tsuyoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya University
Establishment of a novel cell-based assay for detection of potential drug-induced liver injury by considering immune- and inflammatory-related factorsPrincipal Investigator
- Principal Investigator
  
  ODA Shingo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
  Medical pharmacy
- Research Institution
  Nagoya University
Mechanisms by which synthetic cathinones induce neurotoxicity
- Principal Investigator
  
  NAKAJIMA Akira
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Nagoya University

All 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Establishment and characterization of a mouse model of rhabdomyolysis by coadministration of statin and fibrate2019
- Author(s)
  Katsuhito Watanabe, Shingo Oda, Akiko Matsubara, Sho Akai, and Tsuyoshi Yokoi
- Journal Title
  
  Toxicology Letters
  
  Volume: 207 Pages: 49-58
- DOI
  10.1016/j.toxlet.2019.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15503
[Journal Article] Acute kidney injury model established by systemic glutathione depletion in mice2019
- Author(s)
  Matsubara Akiko、Oda Shingo、Jia Ru、Yokoi Tsuyoshi
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: 39 Pages: 919-930
- DOI
  10.1002/jat.3780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15503
[Journal Article] Comprehensive analysis of serum microRNAs in hapatic sinusoidal obstruction syndrome (SOS) in rats: implication as early-phase biomarkers for SOS.2018
- Author(s)
  Takeuchi Masaki、Oda Shingo、Tsuneyama Koichi、Yokoi Tsuyoshi
- Journal Title
  
  Arch. Toxicol.
  
  Volume: 92 Pages: 2947-2962
- DOI
  10.1007/s00204-018-2269-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-16H02616
[Journal Article] Identification of specific microRNA biomarkers in early stage of hepatocellular injury, cholestasis, and steatosis in rat.2018
- Author(s)
  Takumi Kagawa, Yuji Shirai, Shingo Oda and Tsuyoshi Yokoi
- Journal Title
  
  Toxicol. Sci.
  
  Volume: 166 Pages: 228-239
- DOI
  10.1093/toxsci/kfy200
- NAID
  130007432275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02616
[Journal Article] Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin2018
- Author(s)
  Akiko Matsubara, Shingo Oda, Sho Akai, Koichi Tsuneyama, Tsuyoshi Yokoi
- Journal Title
  
  Toxicology Letters
  
  Volume: 291 Pages: 184-193
- DOI
  10.1016/j.toxlet.2018.04.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15503, KAKENHI-PROJECT-18K07069
[Journal Article] MicroRNA in rat liver sinusoidal endothelial cells and hepatocytes and application to circulating biomarkers that discern pathogenesis of liver injuries.2018
- Author(s)
  Shingo Oda, Masaki Takeuchi, Sho Akai, Yuji Shirai, Koichi Tsuneyama, and Tsuyoshi Yokoi
- Journal Title
  
  Am. J. Pathol.
  
  Volume: 188 Pages: 916-928
- DOI
  10.1016/j.ajpath.2017.12.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02616
[Journal Article] Cell-based assay using glutathione-depleted HepaRG human liver cells for predicting drug-induced liver injury.2018
- Author(s)
  Jieyu Xu, Shingo Oda and Tsuyoshi Yokoi
- Journal Title
  
  Toxicol. In Vitro
  
  Volume: 48 Pages: 286-301
- DOI
  10.1016/j.tiv.2018.01.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02616
[Journal Article] Comprehensive hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK-875)-induced acute liver injury in mice.2018
- Author(s)
  Urano Yuya、Oda Shingo、Tsuneyama Koichi、Yokoi Tsuyoshi
- Journal Title
  
  Chem. Biol. Interact.
  
  Volume: 296 Pages: 185-197
- DOI
  10.1016/j.cbi.2018.09.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-16H02616
[Journal Article] Toxicological role of an acyl glucuronide metabolite in diclofenac-induced acute liver injury in mice.2017
- Author(s)
  Oda S, Shirai Y, Akai S, Nakajima A, Tsuneyama K, Yokoi T.
- Journal Title
  
  J. Appl. Toxicol.
  
  Volume: 37 Pages: 545-553
- DOI
  10.1002/jat.3388
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K21057, KAKENHI-PROJECT-16H02616
[Journal Article] stablishment of a mouse model of enalapril-induced liver injury and investigation of a pathogenesis.2017
- Author(s)
  Shirai Y, Oda S, Makino S, Tsuneyama K, Yokoi T.
- Journal Title
  
  Lab. Invest.
  
  Volume: in press Pages: 545-553
- DOI
  10.1038/labinvest.2017.22
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K21057, KAKENHI-PROJECT-16H02616
[Journal Article] Estabolishment of a novel mouse model for pioglitazone-mediated skeletal muscle injuty.2017
- Author(s)
  Sho Akai, Shingo Oda and Tsuyoshi Yokoi
- Journal Title
  
  Toxicology
  
  Volume: 382 Pages: 1-9
- DOI
  10.1016/j.tox.2017.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02616
[Journal Article] Fluoroquinolones and propionic acid derivatives induce inflammatory responses in vitro2017
- Author(s)
  Akira Nakajima, Hiroki Sato, Shingo Oda, Tsuyoshi Yokoi
- Journal Title
  
  Cell Biology and Toxicology
  
  Volume: 印刷中
- DOI
  10.1007/s10565-017-9391-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21057
[Journal Article] 薬物代謝・薬物動態研究の最近の動向と展望 -医薬品開発研究を中心として-2017
- Author(s)
  横井毅、織田進吾
- Journal Title
  
  化学と生物
  
  Volume: 印刷中
- NAID
  130006742949
- Data Source
  KAKENHI-PROJECT-15K21057
[Journal Article] A novel cell-based assay for the evaluation of immune- and inflammatory-related gene expression as biomarkers for the risk assessment of drug-induced liver injury2016
- Author(s)
  Shingo Oda, Kentaro Matsuo, Akira Nakajima, and Tsuyoshi Yokoi.
- Journal Title
  
  Toxicology Letters
  
  Volume: 241 Pages: 60-70
- DOI
  10.1016/j.toxlet.2015.10.029
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21057
[Journal Article] Allopurinol induces innate immune responses through mitogen-activated protein kinase signaling pathways in HL-60 cells2016
- Author(s)
  Akira Nakajima, Shingo Oda, Tsuyoshi Yokoi
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: 36 Pages: 1120-1128
- DOI
  10.1002/jat.3272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21057
[Journal Article] Micro RNA-mediated Th2 bias in the pathogenesis of methimazole-induced acute liver injury in mice.2016
- Author(s)
  Yasuaki Uematsu, Sho Akai, Tomoaki Tochitani, Shingo Oda, Toru Yamada, Tsuyoshi Yokoi
- Journal Title
  
  Toxicol. Appl. Pharmacol.
  
  Volume: 07 Pages: 1-9
- DOI
  10.1016/j.taap.2016.07.008
- NAID
  130005260756
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21057, KAKENHI-PROJECT-15K15001
[Journal Article] Zomepirac acyl glucuronide is responsible for zomepirac-induced acute kidney injury in mice.2016
- Author(s)
  Iwamura A, Watanabe K, Akai S, Nishinosono T, Tsuneyama K, Oda S, Kume T, Yokoi T.
- Journal Title
  
  Drug Metab. Dispos.
  
  Volume: 44 Pages: 888-896
- DOI
  10.1124/dmd.116.069575
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15098, KAKENHI-PROJECT-15K21057, KAKENHI-PROJECT-15K15001
[Journal Article] いまさら聞けない薬物動態Q＆A: 薬剤師が知っておきたい抱合酵素とその基質について教えてください2016
- Author(s)
  織田進吾, 横井　毅
- Journal Title
  
  月刊薬事
  
  Volume: 58 Pages: 685-690
- Data Source
  KAKENHI-PROJECT-15K21057
[Journal Article] いまさら聞けない薬物動態Q＆A. 薬剤師が知っておきたい抱合酵素とその基質について教えてください2016
- Author(s)
  織田進吾, 横井　毅
- Journal Title
  
  月刊薬事
  
  Volume: 58 Pages: 685-690
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] ラットにおける胆汁うっ滞性肝障害のバイオマーカーとしての miR-218a-5p の有用性及びその機能解析2020
- Author(s)
  平吹有香，織田進吾，武内太輝，香川匠，横井毅
- Organizer
  第２回医薬品毒性機序研究会
- Data Source
  KAKENHI-PROJECT-19K07099
[Presentation] Transcriptomic landscape in murine plasma of hepatocellular liver injury for biomarker discovery2019
- Author(s)
  Shingo Oda, Ken Ito, Tsuyoshi Yokoi
- Organizer
  15th IUTOX
- Data Source
  KAKENHI-PROJECT-19K07099
[Presentation] Application of microRNAs derived from liver sinusoidal endothelial cells to circulating biomarkers that discern pathogenesis of liver injuries.2019
- Author(s)
  Shingo Oda, Masaki Takeuchi, Sho Akai, Yuji Shirai, and Tsuyoshi Yokoi.
- Organizer
  58th Annual Meeting of Society of Toxicology, March 10-14, 2019, Baltimore Convention Center, Baltimore, Maryland, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] 胆汁酸塩経口負荷ラットにおける薬剤性肝障害の評価2019
- Author(s)
  織田進吾, 楊馥華, 武内太輝, 横井毅
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19K07099
[Presentation] 薬剤性肝障害動物モデルにおけるバイオマーカーとしての血中マイクロRNAの利用2019
- Author(s)
  織田進吾
- Organizer
  安全性評価研究会　第28回夏フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-19K07099
[Presentation] 胆汁うっ滞性肝障害ラットのバイオマーカーとしてのmicroRNA探索2019
- Author(s)
  平吹有香，織田進吾，武内太輝，香川匠，横井毅
- Organizer
  日本薬物動態学会第34回年会
- Data Source
  KAKENHI-PROJECT-19K07099
[Presentation] Systemic glutathione depletion causes acute kidney injury.2018
- Author(s)
  Akiko Matsubara, Shingo Oda, Ru Jia, and Tsuyoshi Yokoi.
- Organizer
  International Meeting of 22nd Microsomes and Drug Oxidations and 33rd Japanese Society of the Study of Xenobiotics, October 1-5, 2018, Ishikawa Ongakudo Hall, Kanazawa, Ishikawa, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] 病型および臓器特異的な毒性予測バイオマーカーとしてのmiRNA2018
- Author(s)
  横井　毅、香川　匠、　織田進吾
- Organizer
  2018年7月18日-７月20日、第45回日本毒性学会学術年会、大阪国際会議場グランキューブ大阪、大阪府大阪市
- Invited
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] 全身性グルタチオン枯渇は急性腎障害を引き起こす2018
- Author(s)
  松原明子, 織田進吾, 横井毅
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-17K15503
[Presentation] 胆汁うっ滞および脂肪肝を病型別に早期予測が可能な血漿miRNAバイオマーカー探索研究．2018
- Author(s)
  香川　匠、白井勇司、Tomas ZARYBNICKY、織田進吾、横井　毅
- Organizer
  2018年7月18日-７月20日、第45回日本毒性学会学術年会、大阪国際会議場グランキューブ大阪、大阪府大阪市
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] ゲフィチニブ誘導性肝障害マウスモデルの作成及びグルタチオン枯渇の影響．2018
- Author(s)
  織田進吾、宮崎菜々華、賈茹、常山幸一、横井　毅
- Organizer
  2018年7月18日-７月20日、第45回日本毒性学会学術年会、大阪国際会議場グランキューブ大阪、大阪府大阪市
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Establishment of gefitinib-induced liver injury and its pathogenic mechanisms in mice.2018
- Author(s)
  Shingo Oda, Nanaka Miyazaki, Ru Jia, Koichi Tsuneyama, and Tsuyoshi Yokoi.
- Organizer
  The 8th International Congress of Asian Society of Toxicology, June 17-20, 2018, The Royal Cliff Grand Hotel, Pattaya, Thailand.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Individual variability of carbamazepine-induced liver injury in mice.2017
- Author(s)
  Yasuaki Uematsu, Sho Akai, Shingo Oda, Toru Yamada, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology, March 12-16, 2017, Baltimore Convention Center, Baltimore, Maryland, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Characterization of microRNAome in rat liver sinusoidal endothelial cells and hepatocytes and their potential application to plasma biomarkers that discern pathogenesis of liver injuries2017
- Author(s)
  Shingo Oda, Masataka Takeuchi, Yuji Shirai, Sho Akai, Koichi Tsuneyama, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology, March 12-16, 2017, Baltimore Convention Center, Baltimore, Maryland, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Individual variability of carbamazepine-induced liver injury in mice2017
- Author(s)
  Yasuaki Uematsu, Sho Akai, Shingo Oda, Toru Yamada, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Establishment of a mouse model of rhabdomyolysis by combined use of ciprofloxacin and atorvastatin2017
- Author(s)
  Akiko Matsubara, Shingo Oda, Sho Akai, Tsuyoshi Yokoi
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-17K15503
[Presentation] Characterization of microRNAome in rat liver sinusoidal endothelial cells and hepatocytes and their potential application to plasma biomarkers that discern pathogenesis of liver injuries2017
- Author(s)
  Shingo Oda, Masataka Takeuchi, Yuji Shirai, Sho Akai, Koichi Tsuneyama, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Comparison of in vitro cytotoxicity assays using glutathione-depleted HepaRG and HepG2 cells for predicting drug-induced liver injury.2017
- Author(s)
  Jieyu Xu, Shingo Oda, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Comparison of in vitro cytotoxicity assays using glutathione-depleted HepaRG and HepG2 cells for predicting drug-induced liver injury2017
- Author(s)
  Jieyu Xu, Shingo Oda, Tsuyoshi Yokoi
- Organizer
  56th Annual Meeting of Society of Toxicology
- Place of Presentation
  Baltimore Convention Center (Baltimore, USA)
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] Establishment of a novel cell-based assay for drug-induced liver injury (DILI) potential considering immune- and inflammation-related factors.2017
- Author(s)
  Tsuyoshi Yokoi and Shingo Oda.
- Organizer
  56th Annual Meeting of Society of Toxicology, March 12-16, 2017, Baltimore Convention Center, Baltimore, Maryland, USA.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] 抗菌薬シプロフロキサシン及びアトルバスタチンの併用による横紋筋融解症マウスモデルの作出2017
- Author(s)
  松原明子、織田進吾、赤井翔、横井毅
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-17K15503
[Presentation] Characterization of microRNAome in rat liver sinusoidal endothelial cells and hepatocytes and their potential application to plasma biomarkers that discern pathogenesis of liver injuries2017
- Author(s)
  Shingo Oda, Masataka Takeuchi, Yuji Shirai, Sho Akai, Koichi Tsuneyama, Tsuyoshi Yokoi
- Organizer
  56th Annual Meeting of Society of Toxicology
- Place of Presentation
  Baltimore Convention Center (Baltimore, USA)
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] Comparison of in vitro cytotoxicity assays using glutathione-depleted HepaRG and HepG2 cells for predicting drug-induced liver injury.2017
- Author(s)
  Jieyu Xu, Shingo Oda, Tsuyoshi Yokoi.
- Organizer
  56th Annual Meeting of Society of Toxicology, March 12-16, 2017, Baltimore Convention Center, Baltimore, Maryland, USA.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] Establishment and characterization of a mouse model of rhabdomyolysis by administration of statin and fibrate.2017
- Author(s)
  Katsuhiro Watanabe, Shingo Oda, Sho Akai, Akiko Matsubara, and Tsuyoshi Yokoi.
- Organizer
  21th North American ISSX Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02616
[Presentation] 薬剤性肝障害リスク評価におけるグルタチオン枯渇HepaRG細胞の有用性検討2016
- Author(s)
  許潔玉、織田進吾、横井毅
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  愛知県産業労働センターウインクあいち (愛知県名古屋市)
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] ジクロフェナク誘導性肝障害モデルマウスにおけるアシルグルクロン酸代謝物の毒性学的役割の検討2016
- Author(s)
  織田進吾、白井勇司、赤井翔、常山幸一、中島晶、横井毅
- Organizer
  第23回HAB研究機構学術大会
- Place of Presentation
  つくば産業総合技術研究所共用講堂 (茨城県つくば市)
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] In vitro試験系における抗菌剤レボフロキサシンおよび解熱鎮痛消炎剤ロキソプロフェンによる免疫因子の活性化2016
- Author(s)
  中島晶, 佐藤宏樹、織田進吾、横井毅
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  愛知県産業労働センターウインクあいち (愛知県名古屋市)
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] Toxicological role of acylglucuronide metabolite in diclofenac-induced acute liver injury in mice2016
- Author(s)
  Shingo Oda, Yuji Shirai, Sho Akai, Akira Nakajima, Koichi Tsuneyama, Tsuyoshi Yokoi
- Organizer
  The 11th International ISSX Meeting
- Place of Presentation
  BEXCO Convention Center (Busan, Republic of Korea)
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] Mechanisms of drug-induced liver injury (DILI) and establishment of a novel cell-based assay for DILI potential considering immune- and inflammatory-related factors2015
- Author(s)
  Shingo Oda, Tsuyoshi Yokoi
- Organizer
  日本薬物動態学会第30回年会
- Place of Presentation
  タワーホール船堀 (東京都江戸川区)
- Year and Date
  2015-11-12
- Invited
- Data Source
  KAKENHI-PROJECT-15K21057
[Presentation] HepaRG細胞および免疫・炎症関連遺伝子マーカーを用いた薬剤性肝障害リスク評価系の構築2015
- Author(s)
  織田進吾, 松尾研太朗, 深見達基, 中島美紀, 横井毅
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  石川県立音楽堂/金沢市アートホール/ホテル日航金沢 (石川県金沢市)
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-15K21057

1. Yokoi Tsuyoshi (70135226)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
2. NAKAJIMA Akira (20419237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. SHIRAI Yuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. XU Jieyu

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 常山幸一

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results

ODA Shingo 織田 進吾

Research Projects

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Co-Researchers

特異体質性薬物性肝障害発症の個体差の決定因子の解明と予測試験系の開発Ongoing

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Comprehensive functional analysis of lncRNAs in liver fibrosisPrincipal Investigator

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Establishment of animal models and treatment methods for drug-induced rhabdomyolysisPrincipal Investigator

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Establishment of a predictive test system for idiosyncratic drug-induced liver injury and study for evaluation of onset biomarkers

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Establishment of a novel cell-based assay for detection of potential drug-induced liver injury by considering immune- and inflammatory-related factorsPrincipal Investigator

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Mechanisms by which synthetic cathinones induce neurotoxicity

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[Journal Article] Establishment and characterization of a mouse model of rhabdomyolysis by coadministration of statin and fibrate2019

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[Journal Article] Acute kidney injury model established by systemic glutathione depletion in mice2019

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[Journal Article] Comprehensive analysis of serum microRNAs in hapatic sinusoidal obstruction syndrome (SOS) in rats: implication as early-phase biomarkers for SOS.2018

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[Journal Article] Identification of specific microRNA biomarkers in early stage of hepatocellular injury, cholestasis, and steatosis in rat.2018

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[Journal Article] Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin2018

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[Journal Article] MicroRNA in rat liver sinusoidal endothelial cells and hepatocytes and application to circulating biomarkers that discern pathogenesis of liver injuries.2018

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[Journal Article] Cell-based assay using glutathione-depleted HepaRG human liver cells for predicting drug-induced liver injury.2018

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[Journal Article] Comprehensive hepatic transcriptome analyses revealed possible pathogenic mechanisms of fasiglifam (TAK-875)-induced acute liver injury in mice.2018

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ODA Shingo 織田進吾