SATO Yusuke 佐藤悠介

Researcher Number	10735624
Other IDs
External Links
Affiliation (Current)	2019: 北海道大学, 薬学研究院, 助教
Affiliation (based on the past Project Information) *help	2016 – 2019: 北海道大学, 薬学研究院, 助教 2014 – 2015: 北海道大学, 薬学研究科(研究院), 特任助教 2014: 北海道大学, 大学院薬学研究院, 特任助教
Review Section/Research Field	Principal Investigator Physical pharmacy / Medium-sized Section 90:Biomedical engineering and related fields / Biomedical engineering/Biomaterial science and engineering / Medical pharmacy Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 53010:Gastroenterology-related / Drug development chemistry
Keywords	Principal Investigator siRNA / 脂質ナノ粒子 / 粒子径 / ph感受性カチオン性脂質 / in vivoゲノム編集 / pH応答性 / 動態制御 / タンパク質送達 / PEG / がん治療 … More Except Principal Investigator ミトコンドリア遺伝子治療 / 核酸医薬 / 肝線維化 / TLL1 / がん免疫療法 / ヌクレアーゼ抵抗性 / DNMT1 / HCV / SPAAC / 核酸ナノ医療 / miRNA / 細胞内動態制御 / ホスホロチオエート結合 / shRNA / stat3 / 核酸創薬 / PSMA / ホスホジエステル結合 / 組織標的化 / MEND / オリゴヌクレオチド / アンチマイクロRNA / ナノＤＤＳ / 2'-OMe-4'-チオリポヌクレオシド Less

律速段階の解明に基づいたウイルスを凌駕する革新的医薬分子送達システムの創製Ongoing
- Principal Investigator
  
  原島秀吉
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Hokkaido University
Identification of novel therapeutic target for liver fibrosis and elucidation of the mechanismOngoing
- Principal Investigator
  
  田中靖人
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nagoya City University
組織浸透力に優れたsiRNA搭載極小脂質ナノ粒子による新規がん治療Principal InvestigatorOngoing
- Principal Investigator
  
  佐藤悠介
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Hokkaido University
In vivoゲノム編集による肝疾患治療の実現を目指した脂質ナノ粒子の創生Principal InvestigatorOngoing
- Principal Investigator
  
  佐藤悠介
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Hokkaido University
Development of niucleic delivery system for targeting primary and metametastatic tumorPrincipal Investigator
- Principal Investigator
  
  SATO Yusuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Hokkaido University
肝細胞標的siRNA送達システムの創製：体内動態と細胞内動態の真の両立Principal Investigator
- Principal Investigator
  
  佐藤悠介
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Medical pharmacy
- Research Institution
  Hokkaido University
Targeting of the nuclease-resistant functional oligonucleotides
- Principal Investigator
  
  MATSUDA Akira
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hokkaido University

All 2018 2017 2016 2015 2014 2011

All Journal Article Presentation Book

[Book] 医薬ジャーナル　2014年7月号(Vol.50 No.7)2014
- Author(s)
  佐藤悠介・中村孝司・山田勇磨・原島秀吉
- Total Pages
  200
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-26893001
[Book] Advances in Genetics Volume 88 Nonviral Vectors for Gene Therapy Lipid- and Polymer-based Gene Transfer2014
- Author(s)
  Sato Y, Nakamura T, Yamada Y, Akita H, Harashima H.
- Total Pages
  409
- Publisher
  ELSEVIER
- Data Source
  KAKENHI-PROJECT-26893001
[Journal Article] Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers2017
- Author(s)
  Maeki M, Fujishima Y, Sato Y, Yasui T, Kaji N, Ishida A, Tani H, Baba Y, Harashima H, Tokeshi M
- Journal Title
  
  PLoS One
  
  Volume: 12
- DOI
  10.1371/journal.pone.0187962
- Data Source
  KAKENHI-PROJECT-17H05052
[Journal Article] pH-labile PEGylation of siRNA-loaded lipid nanoparticle improves active targeting and gene silencing activity in hepatocytes2017
- Author(s)
  Hashiba K, Sato Y, Harashima H
- Journal Title
  
  J. Control. Release
  
  Volume: 262 Pages: 239-246
- DOI
  10.1016/j.jconrel.2017.07.046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H05052
[Journal Article] Highly specific delivery of siRNA to hepatocytes circumvents endothelial cell-mediated lipid nanoparticle-associated toxicity leading to the safe and efficacious decrease in the hepatitis B virus2017
- Author(s)
  Sato Y, Matsui H, Yamamoto N, Sato R, Munakata T, Kohara M, Harashima H
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 266 Pages: 216-225
- DOI
  10.1016/j.jconrel.2017.09.044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08871, KAKENHI-PROJECT-17H05052, KAKENHI-PROJECT-15K19120
[Journal Article] Innovative Technologies in Nanomedicines: From Passive Targeting to Active Targeting/From Controlled Pharmacokinetics to Controlled Intracellular Pharmacokinetics.2017
- Author(s)
  Sato Y, Sakurai Y, Kajimoto K, Nakamura T, Yamada Y, Akita H, Harashima H.
- Journal Title
  
  Macromol Biosci.
  
  Volume: 17 Pages: 1-16
- DOI
  10.1002/mabi.201600179
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26282131, KAKENHI-PROJECT-26282132, KAKENHI-PROJECT-26713002, KAKENHI-PROJECT-15K20831, KAKENHI-PROJECT-16K11180, KAKENHI-PROJECT-26670741
[Journal Article] マイクロ流体デバイスによる脂質ナノ粒子作製とDDSへの応用2016
- Author(s)
  真栄城正寿, 佐藤悠介, 原島秀吉, 渡慶次学
- Journal Title
  
  機能材料
  
  Volume: 36 Pages: 15-21
- Data Source
  KAKENHI-PROJECT-15K20831
[Journal Article] Elucidation of the physicochemical properties and potency of siRNA-loaded small-sized lipid nanoparticles for siRNA delivery2016
- Author(s)
  Yusuke Sato, Yusuke Note, Masatoshi Maeki, Noritada Kaji, Yoshinobu Baba, Manabu Tokeshi, Hideyoshi Harashima
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 229 Pages: 48-57
- DOI
  10.1016/j.jconrel.2016.03.019
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20831
[Journal Article] Development of a multifunctional envelope-type nano device and its application to nanomedicine2016
- Author(s)
  Sato Y, Nakamura T, Yamada Y, Harashima H.
- Journal Title
  
  J Control Release.
  
  Volume: 244 Pages: 194-204
- DOI
  10.1016/j.jconrel.2016.06.042
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26282131, KAKENHI-PROJECT-26713002, KAKENHI-PROJECT-26670741, KAKENHI-PROJECT-15K20831, KAKENHI-PROJECT-16K11180
[Journal Article] pH感受性脂質を基盤とした脂質ナノ粒子の開発と核酸ナノメディシンへの応用2016
- Author(s)
  佐藤悠介, 原島秀吉
- Journal Title
  
  化学工業
  
  Volume: 67 Pages: 21-27
- Data Source
  KAKENHI-PROJECT-15K20831
[Journal Article] Relationship Between the Physicochemical Properties of Lipid Nanoparticles and the Quality of siRNA Delivery to Liver Cells.2016
- Author(s)
  Yusuke Sato, Hiroto Hatakeyama, Mamoru Hyodo, Hideyoshi Harashima
- Journal Title
  
  Mol Ther.
  
  Volume: 24 Pages: 788-795
- DOI
  10.1038/mt.2015.222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K20831, KAKENHI-PROJECT-26830101
[Journal Article] The RNA sensor RIG-I dually functions as an innate sensor and direct antiviral factor for hepatitis B virus2015
- Author(s)
  Sato S, Li K, Kameyama T, Hayashi T, Ishida Y, Murakami S, Watanabe T, Iijima S, Sakurai Y, Watashi K, Tsutsumi S, Sato Y, Akita H, Wakita T, Rice CM, Harashima H, Kohara M, Tanaka Y, Takaoka A
- Journal Title
  
  Immunity
  
  Volume: 42 Pages: 123-132
- DOI
  10.1016/j.immuni.2014.12.016
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390117, KAKENHI-PROJECT-25870015, KAKENHI-PROJECT-25893001, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-26893001, KAKENHI-PUBLICLY-25114712, KAKENHI-PROJECT-25253030
[Journal Article] In vivo therapeutic potential of Dicer-hunting siRNAs targeting infectious hepatitis C virus.2014
- Author(s)
  Watanabe T, Hatakeyama H, Matsuda-Yasui C, Sato Y, Sudoh M, Takagi A, Hirata Y, Ohtsuki T, Arai M, Inoue K, Harashima H, Kohara M
- Journal Title
  
  Sci Rep
  
  Volume: in press Pages: 4750-4750
- DOI
  10.1038/srep04750
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24107502, KAKENHI-PROJECT-24390117, KAKENHI-PROJECT-24590988, KAKENHI-PUBLICLY-25114712, KAKENHI-PROJECT-25860305, KAKENHI-PROJECT-26893001
[Journal Article] Application of apolipoprotein E-modified liposomal nanoparticles as a carrier for delivering DNA and nucleic acid in the brain.2014
- Author(s)
  Tamaru M, Akita H, Nakatani T, Kajimoto K, Sato Y, Hatakeyama H, Harashima H.
- Journal Title
  
  Int J Nanomedicine
  
  Volume: 9 Pages: 4267-4276
- DOI
  10.2147/ijn.s65402
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26893001
[Journal Article] The systematic administration of an anti-miRNA oligonucleotide encapsulated pH-sensitive liposome results in reduced level of hepatic microRNA-122 in mice.2014
- Author(s)
  Hiroto Hatakeyama, Manami Murata, Yusuke Sato, Mayumi Takahashi, Noriyuki Minakawa, Akira Matsuda, Hideyoshi Harashima
- Journal Title
  
  Journal of Controled Release
  
  Volume: 173 Pages: 43-50
- DOI
  10.1016/j.jconrel.2013.10.023
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05557, KAKENHI-PROJECT-23249008, KAKENHI-PUBLICLY-24107502, KAKENHI-PUBLICLY-24107518
[Journal Article] Multifunctional envelope-type nano device for controlled intracellular trafficking and selective targeting in vivo.2014
- Author(s)
  Kazuaki Kajimoto, Yusuke Sato, Takashi Nakamura, Yuma Yamada, Hidesyoshi Harashima.
- Journal Title
  
  J Control Release
  
  Volume: 190 Pages: 593-606
- DOI
  10.1016/j.jconrel.2014.03.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25560219, KAKENHI-PROJECT-26282131, KAKENHI-PROJECT-26893001
[Journal Article] Selective transcription of an unnatural Naphthyridine:Imidazopyridopyrimidine base pair containing four hydrogen bonds with T7 RNA polymerase.2014
- Author(s)
  Nomura, Y.; Kashiwagi, S.; Sato, K.; Matsuda, A.
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 53 Pages: 12844-12848
- DOI
  10.1002/anie.201406402
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249008, KAKENHI-PROJECT-25410165
[Journal Article] An apolipoprotein E modified liposomal nanoparticle: ligand dependent efficiency as a siRNA delivery carrier for mouse-derived brain endothelial cells.2014
- Author(s)
  Mina Tamaru, Hidetaka Akita, Kazuaki Kajimoto, Yusuke Sato, Hiroto Hatakeyama, Hideyoshi Harashima
- Journal Title
  
  Int J Pharm
  
  Volume: 465 Pages: 77-82
- DOI
  10.1016/j.ijpharm.2014.02.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05557, KAKENHI-PROJECT-11J05746, KAKENHI-PROJECT-26893001
[Journal Article] Highly Fluorescent 5-(5,6-Dimethoxy- benzothiazol-2-yl)-2'-Deoxyuridine 5'-Triphosphate as an Efficient Substrate for DNA Polymerases2011
- Author(s)
  Sato, K.
- Journal Title
  
  ChemBioChem
  
  Volume: 12 Pages: 2341-2346
- DOI
  10.1002/cbic.201100452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249008, KAKENHI-PROJECT-23750178
[Presentation] 優れたsiRNA送達効率と安全性を両立する脂質ナノ粒子の開発2018
- Author(s)
  佐藤悠介, 橋場一毅, 原島秀吉.
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-17H05052
[Presentation] 効率的なin vivo核酸送達を実現する高機能脂質ナノ粒子2018
- Author(s)
  佐藤悠介, 橋場一毅, 原島秀吉.
- Organizer
  第27回インテリジェント材料・システムシンポジウム
- Data Source
  KAKENHI-PROJECT-17H05052
[Presentation] Targeted delivery of siRNAs by manipulating acid dissociation constant of lipid nanoparticles2017
- Author(s)
  Shobaki N, Sato Y, Harashima H.
- Organizer
  The 5th International Life Science Symposium for Young Scientists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05052
[Presentation] 脂質ナノ粒子の膜酸乖離定数の操作による細胞選択的なsiRNA送達2017
- Author(s)
  ショバキヌレ, 佐藤悠介, 原島秀吉.
- Organizer
  第3回日本核酸医薬学会
- Data Source
  KAKENHI-PROJECT-17H05052
[Presentation] メカニズムに基づいた安全性の高いsiRNA搭載脂質ナノ粒子の開発とB型肝炎治療への応用2017
- Author(s)
  佐藤悠介, 松井秀樹, 佐藤里咲, 原島秀吉
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K20831
[Presentation] 機能性脂質を基盤としたin vivo核酸送達システムの開発2017
- Author(s)
  佐藤悠介.
- Organizer
  日本薬学会北海道支部主催第1回若手シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H05052
[Presentation] 肝臓標的型siRNA送達システムの安全性向上に関する検討2017
- Author(s)
  佐藤里咲, 佐藤悠介, 松井秀樹, 原島秀吉
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K20831
[Presentation] 新規pH応答性脂質の開発による効率的なin vivo siRNAデリバリー2017
- Author(s)
  橋場一毅, 佐藤悠介, 原島秀吉.
- Organizer
  第39回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-17H05052
[Presentation] 肝臓を標的としたsiRNA搭載脂質ナノ粒子の物理化学的性質がsiRNA導入効率に及ぼす影響の評価2016
- Author(s)
  佐藤悠介, 野手雄介, ショバキヌレ, 原島秀吉
- Organizer
  第2回日本核酸医薬学会
- Place of Presentation
  東京理科大学（東京都葛飾区）
- Year and Date
  2016-11-15
- Data Source
  KAKENHI-PROJECT-15K20831
[Presentation] Optimizing siRNA delivery using specific multifunctional envelope-type nanodevice for liver sinusoidal endothelial cells2016
- Author(s)
  Shobaki N, Sato Y, Harashima H
- Organizer
  AsiaNANO 2016: Asian Conference on Nanoscience and Nanotechnology
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-10-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20831
[Presentation] pH応答性脂質ナノ粒子による肝実質細胞選択的なsiRNA導入とB型肝炎治療2015
- Author(s)
  佐藤悠介, 畠山浩人, 兵藤守, 山本直樹, 小原道法, 原島秀吉
- Organizer
  第37回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  熊本大学（熊本県熊本市）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15K20831
[Presentation] Elucidation of the physicochemical properties and potency for siRNA delivery of the siRNA-loaded small-sized nanoparticles2015
- Author(s)
  Yusuke Note, Yusuke Sato, Masatoshi Maeki, Manabu Tokeshi, Hideyoshi Harashima
- Organizer
  The 18th Hokkaido University-Seoul National University Joint Sympojium
- Place of Presentation
  Seoul National University（韓国・ソウル）
- Year and Date
  2015-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20831
[Presentation] Development of siRNA delivery system for the treatment of hepatitis B viral infection2015
- Author(s)
  Yusuke Sato, Hiroto Hatakeyama, Naoki Yamamoto, Michinori Kohara, Hideyoshi Harashima
- Organizer
  The 18th Hokkaido University-Seoul National University Joint Sympojium
- Place of Presentation
  Seoul National University（韓国・ソウル）
- Year and Date
  2015-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20831

1. MATSUDA Akira (90157313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. SATO Kosuke (70415686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 原島秀吉 (00183567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 中村孝司 (20604458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 山田勇磨 (60451431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 田中靖人 (90336694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大石久史 (30375513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. AKITA Hidetaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. KITA Tomoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 畠山浩人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 小原道法

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 安井文彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 平田雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 渡邊綱正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 大槻貴博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 佐藤精一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 櫻井遊

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 渡士幸一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 高岡晃教

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 南川典昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 棟方翼

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 山本直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 梶本和昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 兵藤守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SATO Yusuke 佐藤 悠介

Research Projects

Research Products

Co-Researchers

律速段階の解明に基づいたウイルスを凌駕する革新的医薬分子送達システムの創製Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel therapeutic target for liver fibrosis and elucidation of the mechanismOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

組織浸透力に優れたsiRNA搭載極小脂質ナノ粒子による新規がん治療Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In vivoゲノム編集による肝疾患治療の実現を目指した脂質ナノ粒子の創生Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of niucleic delivery system for targeting primary and metametastatic tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肝細胞標的siRNA送達システムの創製：体内動態と細胞内動態の真の両立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Targeting of the nuclease-resistant functional oligonucleotides

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 医薬ジャーナル 2014年7月号(Vol.50 No.7)2014

Author(s)

Total Pages

Publisher

Data Source

[Book] Advances in Genetics Volume 88 Nonviral Vectors for Gene Therapy Lipid- and Polymer-based Gene Transfer2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] pH-labile PEGylation of siRNA-loaded lipid nanoparticle improves active targeting and gene silencing activity in hepatocytes2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Highly specific delivery of siRNA to hepatocytes circumvents endothelial cell-mediated lipid nanoparticle-associated toxicity leading to the safe and efficacious decrease in the hepatitis B virus2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Innovative Technologies in Nanomedicines: From Passive Targeting to Active Targeting/From Controlled Pharmacokinetics to Controlled Intracellular Pharmacokinetics.2017

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[Journal Article] マイクロ流体デバイスによる脂質ナノ粒子作製とDDSへの応用2016

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SATO Yusuke 佐藤悠介

[Book] 医薬ジャーナル　2014年7月号(Vol.50 No.7)2014