FUJIMURA Atsushi 藤村篤史

… Alternative Names

Researcher Number	10771082
Other IDs
Affiliation (Current)	2021: 岡山大学, 医歯薬学域, 助教
Affiliation (based on the past Project Information) *help	2017 – 2020: 岡山大学, 医歯薬学総合研究科, 助教 2016: 熊本大学, 大学院生命科学研究部(医), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / General physiology
Keywords	Principal Investigator tRNA修飾酵素 / 翻訳メカニズム / 癌幹細胞 / 低分子化合物スクリーニング / tRNA修飾 / 薬剤開発 / 癌転移・浸潤 / Hippo経路 / 創薬 / がん幹細胞 … More

膠芽腫幹細胞を標的としたtRNAメチル化酵素阻害剤による制がん戦略の構築Principal InvestigatorOngoing
- Principal Investigator
  
  藤村篤史
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Okayama University
Development of anti-cancer strategy by targeting tRNA modification enzymesPrincipal Investigator
- Principal Investigator
  
  Fujimura Atsushi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Okayama University
Development of anticancer drugs based on the knowledge of the roles of Ftsj1-mediated tRNA modificationPrincipal Investigator
- Principal Investigator
  
  Fujimura Atsushi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Okayama University
  Kumamoto University

All 2020 2019 2018 2017 2016

All Journal Article Presentation Patent

[Journal Article] Intracranial Mesenchymal Chondrosarcoma Lacking the Typical Histopathological Features Diagnosed by <i>HEY1-NCOA2</i> Gene Fusion2020
- Author(s)
  Uneda A, Kurozumi K, Fujimura A, Kamiya A, Hirose T, Yanai H, Date I.
- Journal Title
  
  NMC Case Report Journal
  
  Volume: 7 Issue: 2 Pages: 47-52
- DOI
  10.2176/nmccrj.cr.2019-0123
- ISSN
  2188-4226
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15241
[Journal Article] Annexin A2-STAT3-Oncostatin M receptor axis drives phenotypic and mesenchymal changes in glioblastoma.2020
- Author(s)
  Matsumoto Y , Ichikawa T , Kurozumi K , Otani Y , Fujimura A , Fujii K , Tomita Y , Hattori Y , Uneda A , Tsuboi N , Kaneda K , Makino K , Date I
- Journal Title
  
  Acta Neuropathol Commun.
  
  Volume: ー Pages: 42-42
- DOI
  10.1186/s40478-020-00916-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16560, KAKENHI-PROJECT-17K10865, KAKENHI-PROJECT-18K15241
[Journal Article] 2-Methylthio Conversion of N6-Isopentenyladenosine in Mitochondrial tRNAs by CDK5RAP1 Promotes the Maintenance of Glioma-Initiating Cells.2019
- Author(s)
  Yamamoto Takahiro、Fujimura Atsushi、Wei Fan-Yan、Shinojima Naoki、Kuroda Jun-ichiro、Mukasa Akitake、Tomizawa Kazuhito
- Journal Title
  
  iScience
  
  Volume: 21 Pages: 42-56
- DOI
  10.1016/j.isci.2019.10.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02865, KAKENHI-PROJECT-17KT0054, KAKENHI-PROJECT-18K15241
[Journal Article] Defective mitochondrial tRNA taurine modification activates global protcostress and leads to mitochondrial disease.2018
- Author(s)
  Fakruddin, M., Wei, F. Y., Suzuki, T., Asano, K., Kaieda, T., Omori, A., Izumi, R., Fujimura, A., Kaitsuka, T., Miyata, K., Araki, K., Oike, Y., Scorrano, L., Suzuki, T. and Tomizawa, K.
- Journal Title
  
  Cell Rep
  
  Volume: 22 Pages: 482-496
- DOI
  10.1016/j.celrep.2017.12.051
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0054, KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-16K15482, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K19521, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-16K18989
[Journal Article] Reactive sulfur species regulate tRNA methylthiolation and contribute to insulin secretion2017
- Author(s)
  Takahashi N, Wei FY, Watanabe S, Hirayama M, Ohuchi Y, Fujimura A, Kaitsuka T, Ishii I, Sawa T, Nakayama H, Akaike T, Tomizawa K.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 45 Pages: 435-445
- DOI
  10.1093/nar/gkw745
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-16K15194, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-16K18989, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-15K11296, KAKENHI-PROJECT-16H05107
[Journal Article] Mtu1-mediated thiouridine formation of mitochondrial tRNAs is required for mitochondrial translation and is involved in reversible infantile liver2016
- Author(s)
  Wu, Y., Wei, F. Y., Kawarada, L., Suzuki, T., Araki, K., Komohara, Y., Fujimura, A., Kaitsuka, T., Takeya, M., Oike, Y., Suzuki, T., Tomizawa, K.
- Journal Title
  
  PLoS Genet.
  
  Volume: 12
- DOI
  10.1371/journal.pgen.1006355
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-15K08178, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K18989, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-26220205
[Journal Article] HDAC9 regulates the alternative lengthening of telomere (ALT) pathway via the formation of ALT-associated PML bodies.2016
- Author(s)
  Mohd. Raeed Jamiruddin, Taku Kaitsuka, Farzana Hakim, Atsushi Fujimura, Fan-Yan Wei, Hisato Saitoh, Kazuhito Tomizawa
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 481 Pages: 25-30
- DOI
  10.1016/j.bbrc.2016.11.026
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18971, KAKENHI-PROJECT-15K08178, KAKENHI-PROJECT-16K18989, KAKENHI-PROJECT-15F15110
[Patent] ホウ素中性子捕捉療法の効果を最適化するがん病巣組織評価2018
- Inventor(s)
  藤村篤史、松井秀樹
- Industrial Property Rights Holder
  藤村篤史、松井秀樹
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-18K15241
[Presentation] ミトコンドリアによる細胞障害性修飾核酸の解毒作用は悪性脳腫瘍幹細胞の維持に必須である2020
- Author(s)
  （口頭発表）藤村篤史、山本隆広、魏范研、富澤一仁
- Organizer
  第97回日本生理学会（コロナ禍により、誌上開催）
- Data Source
  KAKENHI-PROJECT-18K15241
[Presentation] Lineage-restricted dedifferentiation of neurons by transient expression of YAP-TAZ2018
- Author(s)
  藤村篤史
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K18989
[Presentation] Defining the molecular characteristics of boron compounds proposes the concept of precision medicine in BNCT field2018
- Author(s)
  Seiji Yasui, Atsushi Fujimura, Hiroyuki Michiue, Yasuaki Ichikawa, Shuichi Furuya, Mitsunobu Kano, Hideki Matsui
- Organizer
  ICNCT 18th
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15241
[Presentation] 修飾ヌクレオチドの排出機構2017
- Author(s)
  森岡太意気、魏范研、藤村篤史、富澤一仁
- Organizer
  第９４回日本生理学会大会
- Place of Presentation
  静岡県浜松市
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K18989
[Presentation] tRNA修飾酵素FTSJ1による癌進展制御機構2017
- Author(s)
  山村遼介、藤村篤史、永芳友、魏范研、貝塚拓、富澤一仁
- Organizer
  第９４回日本生理学会大会
- Place of Presentation
  静岡県浜松市
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K18989
[Presentation] FTSJ1依存性翻訳機構による転写因子ネットワーク維持は悪性脳腫瘍幹細胞に必須である2017
- Author(s)
  藤村篤史、山村遼介、山本隆広、魏范研、貝塚拓、富澤一仁
- Organizer
  第９４回日本生理学会大会
- Place of Presentation
  静岡県浜松市
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K18989
[Presentation] Ftsj1 determines cancer stem cell-related traits of breast and gastric cancer2016
- Author(s)
  Atsushi Fujimura, Ryosuke Yamamura, Yu Nagayoshi, Fan-Yan Wei, Taku Kaitsuka, Kazuhito Tomizawa
- Organizer
  tRNA 26th Conference
- Place of Presentation
  Jeju, South Korea
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18989

1. 石川吉伸 (00305004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 黒住和彦 (20509608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 富澤一仁 (40274287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 安藤隆幸 (40402226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 増本年男 (40715083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中村仁 (50828407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 魏范研 (90555773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. SUZUKI Takeo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. WATANABE Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. NAKAYAMA Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 鈴木勉

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 荒木喜美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 赤池孝章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 澤智裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 石井功

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 市川智継

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 荒木正健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 貝塚拓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. HAKIM FARZANA

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

FUJIMURA Atsushi 藤村 篤史

Fujimura Atsushi 藤村 篤史

Research Projects

Research Products

Co-Researchers

膠芽腫幹細胞を標的としたtRNAメチル化酵素阻害剤による制がん戦略の構築Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of anti-cancer strategy by targeting tRNA modification enzymesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of anticancer drugs based on the knowledge of the roles of Ftsj1-mediated tRNA modificationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Intracranial Mesenchymal Chondrosarcoma Lacking the Typical Histopathological Features Diagnosed by <i>HEY1-NCOA2</i> Gene Fusion2020

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Annexin A2-STAT3-Oncostatin M receptor axis drives phenotypic and mesenchymal changes in glioblastoma.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 2-Methylthio Conversion of N6-Isopentenyladenosine in Mitochondrial tRNAs by CDK5RAP1 Promotes the Maintenance of Glioma-Initiating Cells.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Defective mitochondrial tRNA taurine modification activates global protcostress and leads to mitochondrial disease.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reactive sulfur species regulate tRNA methylthiolation and contribute to insulin secretion2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mtu1-mediated thiouridine formation of mitochondrial tRNAs is required for mitochondrial translation and is involved in reversible infantile liver2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HDAC9 regulates the alternative lengthening of telomere (ALT) pathway via the formation of ALT-associated PML bodies.2016

Author(s)

Journal Title

DOI

Data Source

[Patent] ホウ素中性子捕捉療法の効果を最適化するがん病巣組織評価2018

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] ミトコンドリアによる細胞障害性修飾核酸の解毒作用は悪性脳腫瘍幹細胞の維持に必須である2020

Author(s)

Organizer

Data Source

[Presentation] Lineage-restricted dedifferentiation of neurons by transient expression of YAP-TAZ2018

Author(s)

Organizer

Data Source

[Presentation] Defining the molecular characteristics of boron compounds proposes the concept of precision medicine in BNCT field2018

Author(s)

Organizer

Data Source

[Presentation] 修飾ヌクレオチドの排出機構2017

Author(s)

FUJIMURA Atsushi 藤村篤史

Fujimura Atsushi 藤村篤史