Kunisada Yuki 國定勇希

Researcher Number	10779416
Other IDs	https://orcid.org/0000-0001-6356-0740
Affiliation (Current)	2025: 岡山大学, 医歯薬学域, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 岡山大学, 医歯薬学域, 助教 2021: 岡山大学, 医歯薬学域, 助教 2019 – 2020: 岡山大学, 医歯薬学総合研究科, 助教 2017 – 2019: 岡山大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 57020:Oral pathobiological science-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor therapeutics Except Principal Investigator Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 制御性T細胞 / 腫瘍免疫 / 制御性T細胞（Treg） / がん免疫 / 制御性T細胞（Treg) / 代謝 / 腫瘍浸透ペプチドiRGD / がん免疫療法 / 免疫組織化学 / 脂肪酸合成阻害剤 … More / 免疫細胞 / 脂質代謝 / 癌細胞 / 口腔癌 / 脂肪酸合成 / 癌 / メトホルミン / Treg … More Except Principal Investigator Hedgehog / 癌骨破壊 / ヘッジホッグ / 血管新生 / 破骨細胞 / 顎骨破壊 / 口腔癌 / 骨破壊 / 癌 Less

To elucidate the mechanism of inhibition of Treg induction by tumor penetrating peptide iRGD.Principal Investigator
- Principal Investigator
  
  國定勇希
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Okayama University
Basic research on novel immunosuppression-releasing therapies targeting lipid metabolismPrincipal Investigator
- Principal Investigator
  
  Kunisada Yuki
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Okayama University
The study of the regulatory mechanisms of cancer bone destruction metabolism and immunity in Hedgehog signaling
- Principal Investigator
  
  SHIMO Tsuyoshi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Regulation of function and antitumor effect of regulatory T cells in the tumor microenvironment by metformine, a type 2 diabetes drugPrincipal Investigator
- Principal Investigator
  
  Kunisada Yuki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Okayama University

All 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Expression of Neurokinin B Receptor in the Gingival Squamous Cell Carcinoma Bone Microenvironment2021
- Author(s)
  Shoko Yoshida, Tsuyoshi Shimo, Kiyofumi Takabatake, Yurika Murase, Kyoichi Obata, Tatsuo Okui, Yuki Kunisada, Soichiro Ibaragi, Hitoshi Nagatsuka, Akira Sasaki
- Journal Title
  
  Diagnostics (Basel, Switzerland)
  
  Volume: 11 Pages: 1044-1044
- NAID
  120007116755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02999
[Journal Article] High-mobility group box 1 induces bone destruction associated with advanced oral squamous cancer via RAGE and TLR42020
- Author(s)
  Sakamoto Yumi、Okui Tatsuo、Yoneda Toshiyuki、Ryumon Shoji、Nakamura Tomoya、Kawai Hotaka、Kunisada Yuki、Ibaragi Soichiro、Masui Masanori、Ono Kisho、Obata Kyoichi、Shimo Tsuyoshi、Sasaki Akira
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 531 Issue: 3 Pages: 422-430
- DOI
  10.1016/j.bbrc.2020.07.120
- NAID
  120006890006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17224, KAKENHI-PROJECT-18H02999, KAKENHI-PROJECT-20H03859, KAKENHI-PROJECT-20H03889
[Journal Article] Expression and Role of IL-1β Signaling in Chondrocytes Associated with Retinoid Signaling during Fracture Healing2020
- Author(s)
  Shimo Tsuyoshi、Takebe Hiroaki、Okui Tatsuo、Kunisada Yuki、Ibaragi Soichiro、Obata Kyoichi、Kurio Naito、Shamsoon Karnoon、Fujii Saki、Hosoya Akihiro、Irie Kazuharu、Sasaki Akira、Iwamoto Masahiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 7 Pages: 2365-2365
- DOI
  10.3390/ijms21072365
- NAID
  120007127458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17090, KAKENHI-PROJECT-18K09641, KAKENHI-PROJECT-19K10171, KAKENHI-PROJECT-18H02999
[Journal Article] High mobility group box 1 induces bone pain associated with bone invasion in a mouse model of advanced head and neck cancer2020
- Author(s)
  Nakamura Tomoya、Okui Tatsuo、Hasegawa Kazuaki、Ryumon Shoji、Ibaragi Soichiro、Ono Kisho、Kunisada Yuki、Obata Kyoichi、Masui Masanori、Shimo Tsuyoshi、Sasaki Akira
- Journal Title
  
  Oncology Reports
  
  Volume: 44 Issue: 6 Pages: 2547-2558
- DOI
  10.3892/or.2020.7788
- NAID
  120007004824
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02999, KAKENHI-PROJECT-20H03889
[Journal Article] Ammonium trtrathiomolybdate enhances the anti tumor effect of cisplatin via the suppression of ATPase copper transporting beta in head and neck squamous cell carcinoma2019
- Author(s)
  Ryumon S., Okui T.,Kunisada Y., Kishimoto K., Shimo T., Hasegawa K., Ibaragi S., Akiyama K., Thi Thu Ha N., Hassan NMM., Sasaki A.
- Journal Title
  
  Oncology Reports
  
  Volume: 42 Pages: 2611-2621
- DOI
  10.3892/or.2019.7367
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04405, KAKENHI-PROJECT-18H02999
[Journal Article] Retinoic Receptor Signaling Regulates Hypertrophic Chondrocyte-specific Gene Expression2019
- Author(s)
  SHIMO TSUYOSHI、KOYAMA EIKI、OKUI TATSUO、MASUI MASANORI、KUNISADA YUKI、IBARAGI SOICHIRO、YOSHIOKA NORIE、KURIO NAITO、YOSHIDA SHOKO、SASAKI AKIRA、IWAMOTO MASAHIRO
- Journal Title
  
  In Vivo
  
  Volume: 33 Issue: 1 Pages: 85-91
- DOI
  10.21873/invivo.11443
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02999
[Presentation] 2型糖尿病薬メトホルミンによる腫瘍局所の制御性T細胞抑制による抗腫瘍効果2018
- Author(s)
  國定勇希，佐々木　朗
- Organizer
  第72回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15025
[Presentation] 腫瘍微小環境の代謝改変は免疫を介して腫瘍増殖を抑制する2018
- Author(s)
  鵜殿平一郎，西田充香子，榮川伸吾，國定勇希，上原健敬
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K15025
[Presentation] 2型糖尿病薬メトホルミンによる腫瘍内制御性T細胞の機能抑制2017
- Author(s)
  國定勇希
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-17K15025

1. SHIMO Tsuyoshi (40362991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 佐々木朗 (00170663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 吉田祥子 (00616047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 青山絵理子 (10432650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 滝川正春 (20112063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 奥井達雄 (40610928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 長塚仁 (70237535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 高畠清文 (70736537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 久保田聡 (90221936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 河合穂高 (10803687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. UDONO Heiichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. EIKAWA Shingo

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. IBARAGI Soichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 建部廣明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 岸本晃治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kunisada Yuki 國定 勇希

Research Projects

Research Products

Co-Researchers

To elucidate the mechanism of inhibition of Treg induction by tumor penetrating peptide iRGD.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic research on novel immunosuppression-releasing therapies targeting lipid metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of the regulatory mechanisms of cancer bone destruction metabolism and immunity in Hedgehog signaling

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of function and antitumor effect of regulatory T cells in the tumor microenvironment by metformine, a type 2 diabetes drugPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression of Neurokinin B Receptor in the Gingival Squamous Cell Carcinoma Bone Microenvironment2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] High-mobility group box 1 induces bone destruction associated with advanced oral squamous cancer via RAGE and TLR42020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Expression and Role of IL-1β Signaling in Chondrocytes Associated with Retinoid Signaling during Fracture Healing2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] High mobility group box 1 induces bone pain associated with bone invasion in a mouse model of advanced head and neck cancer2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Ammonium trtrathiomolybdate enhances the anti tumor effect of cisplatin via the suppression of ATPase copper transporting beta in head and neck squamous cell carcinoma2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Retinoic Receptor Signaling Regulates Hypertrophic Chondrocyte-specific Gene Expression2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] 2型糖尿病薬メトホルミンによる腫瘍局所の制御性T細胞抑制による抗腫瘍効果2018

Author(s)

Organizer

Data Source

[Presentation] 腫瘍微小環境の代謝改変は免疫を介して腫瘍増殖を抑制する2018

Author(s)

Organizer

Data Source

[Presentation] 2型糖尿病薬メトホルミンによる腫瘍内制御性T細胞の機能抑制2017

Author(s)

Organizer

Data Source

Kunisada Yuki 國定勇希