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Sada Masafumi  佐田 政史

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SADA Masafumi  佐田 政史

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Researcher Number 10783508
Other IDs
Affiliation (Current) 2025: 九州大学, 医学研究院, 共同研究員
Affiliation (based on the past Project Information) *help 2023 – 2024: 九州大学, 医学研究院, 共同研究員
2020 – 2022: 九州大学, 大学病院, 助教
2016 – 2019: 九州大学, 医学研究院, 共同研究員
Review Section/Research Field
Principal Investigator
Basic Section 55020:Digestive surgery-related / Digestive surgery
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related / Basic Section 55020:Digestive surgery-related / Digestive surgery
Keywords
Principal Investigator
大腸癌 / ニッチ因子 / 癌関連線維芽細胞 / 膵癌 / 好中球 / 空間的トランスクリプトーム解析 / 癌関連線維芽細胞 (CAF) / 腫瘍微小環境 (TME) / 腫瘍微小環境 / heterogeneity … More / CAF / 転移形成ニッチ因子 / 大腸癌オルガノイド / 大腸癌肝転移 / オルガノイド / 門脈循環腫瘍細胞 / 微小環境因子 / 膵癌肝転移 / CD110 / NETs / 微小転移 / 微小環境 / 遺伝子改変膵癌モデルマウス(KPCマウス) / 微小転移巣 / DNaseⅠ / NETs / 肝微小転移巣形成促進性ニッチ … More
Except Principal Investigator
膵癌 / 樹状細胞 / 腫瘍微小環境 / 樹状細胞(DC) / scRNA-seq / 免疫微小環境 / 大腸癌 / 腫瘍免疫微小環境 / 腫瘍免疫 / オルガノイド / CAF / ゲノムワイドスクリーニング / 癌微小環境 / 免疫療法 / Genom wide screening / CRISPR-Cas9 / 個別化治療 / シングルセル遺伝子発現解析 / 集学的個別化治療 / サブタイプ分類 / 治療の個別化 / 免疫治療 / 膵癌サブタイプ分類 / 癌免疫微小環境 / 微小環境 / 腫瘍関連好中球 / マイクロバイオーム / 抗腫瘍免疫 / single cell RNA-sequence / 食道癌 / single cell RNA sequence / 腸内細菌叢 / CMS / CMS分類 / microbiome / 腫瘍免疫療法 / Autophagy抑制 / 膵癌微小環境 / 膵癌間質 / Autophagy / PSC / clearance / 腹膜播種 / organoid / 脂肪由来間質細胞 / spheroid / leading cell / 腹膜中皮細胞 / 播種 Less
  • Research Projects

    (11 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (14 People)
  •  TIME誘導能に応じた膵癌サブタイプ分類と個別TIME改変を目指した新規治療戦略

    • Principal Investigator
      大内田 研宙
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  網羅的解析による膵癌免疫抑制環境メカニズムの解明

    • Principal Investigator
      三好 圭
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kyushu University
  •  Autophagyに着目した、膵癌における免疫抑制微小環境の解明と新規治療開発

    • Principal Investigator
      当間 宏樹
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  腸内細菌叢による大腸癌subtypingとその免疫微小環境のscRNAseq解析

    • Principal Investigator
      永吉 絹子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  食道癌TMEのscRNA-seq解析によるDC機能不全の解明とその克服に向けて

    • Principal Investigator
      宮坂 義浩
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  マイクロバイオームと腫瘍関連好中球から見た膵がんミニエコシステム

    • Principal Investigator
      池永 直樹
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  Spatial transcriptome analysis reveals CAF-induced colorectal cancer immune remodeling mechanismPrincipal Investigator

    • Principal Investigator
      SADA Masafumi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Identification of niche factors for metastasis formation and development of therapies targeting those factors using colon cancer organoidsPrincipal Investigator

    • Principal Investigator
      SADA Masafumi
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Cellular clearance leading to peritoneal dissemination of pancreatic cancer and a new role of peritoneal mesothelium -From defense to promotion-

    • Principal Investigator
      INOUE Shigetaka
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  To elucidate niche factors promoting micro liver metastasis of pancreatic cancer using genetically engineered model mice.Principal Investigator

    • Principal Investigator
      SADA Masafumi
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  遺伝子改変膵癌モデルマウスを使用した肝微小転移巣形成促進性ニッチ因子の解明Principal Investigator

    • Principal Investigator
      佐田 政史
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University

All 2023 2022 2021 2018

All Journal Article Presentation

  • [Journal Article] Pancreatic stellate cells reorganize matrix components and lead pancreatic cancer invasion via the function of Endo1802018

    • Author(s)
      Koikawa K, Ohuchida K, Takesue S, Ando Y, Kibe S, Nakayama H, Endo S, Abe T, Okumura T, Horioka K, Sada M, Iwamoto C, Moriyama T, Nakata K, Miyasaka Y, Ohuchida R, Manabe T, Ohtsuka T, Nagai E, Mizumoto K, Hashizume M, Nakamura M.
    • Journal Title

      Cancer Letters

      Volume: 412 Pages: 143-154

    • DOI

      10.1016/j.canlet.2017.10.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10597, KAKENHI-PROJECT-16K10599, KAKENHI-PROJECT-16K10601, KAKENHI-PROJECT-17K10700, KAKENHI-PROJECT-17K10701, KAKENHI-PROJECT-17K19607, KAKENHI-PROJECT-17K16563, KAKENHI-PROJECT-17K16566, KAKENHI-PLANNED-26108010, KAKENHI-PROJECT-15H04933, KAKENHI-PROJECT-16H06258, KAKENHI-PROJECT-16J03962, KAKENHI-PROJECT-15K09046, KAKENHI-PROJECT-15K10185, KAKENHI-PROJECT-15K10187, KAKENHI-PROJECT-15K10189, KAKENHI-PROJECT-16K19937, KAKENHI-ORGANIZER-26108001, KAKENHI-PROJECT-16K10600, KAKENHI-INTERNATIONAL-15K21716
  • [Presentation] FAP発癌過程におけるTregの免疫抑制能の変化2023

    • Author(s)
      久野恭子、水内祐介、大内田研宙、片山直樹、堤 親範、中村祥一、奥田 翔、大坪慶志輝、寅田信博、佐田政史、田村公二、永吉絹子、中村雅史
    • Organizer
      第123回日本外科学会定期学術学会
    • Data Source
      KAKENHI-PROJECT-22K07283
  • [Presentation] FAP発癌過程におけるTregの免疫抑制能の変化2023

    • Author(s)
      久野恭子、水内祐介、大内田研宙、片山直樹、堤 親範、中村祥一、奥田 翔、大坪慶志輝、寅田信博、佐田政史、田村公二、永吉絹子、中村雅史
    • Organizer
      第123回日本外科学会定期学術学会
    • Data Source
      KAKENHI-PROJECT-21K08713
  • [Presentation] Single cell RNA sequenceを用いた家族性大腸腺腫症各発がん段階のCD4+ Tcellの比較2022

    • Author(s)
      久野恭子、水内祐介、大内田研宙、堤親範、中村祥一、奥田翔、大坪慶志輝、寅田信博、佐田政史、田村公二、永吉絹子、進藤幸治、仲田興平、森山大樹、中村雅史
    • Organizer
      第29回日本消化器関連学会週間(JDDW 2021)
    • Data Source
      KAKENHI-PROJECT-22K07283
  • [Presentation] Single cell RNA sequenceを用いた家族性大腸腺腫症におけるmacrophageのheterogeneityの解明2021

    • Author(s)
      久野恭子、水内祐介、大内田研宙、中村祥一、奥田翔、大坪慶志輝、佐田政史、永吉絹子、寅田信博、進藤幸治、仲田興平、森山大樹、永井俊太郎、中村雅史
    • Organizer
      第29回日本消化器関連学会週間(JDDW 2021)
    • Data Source
      KAKENHI-PROJECT-21K08713
  • 1.  森山 大樹 (70586859)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 2.  三好 圭 (70755272)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  阿部 俊也 (20722028)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  永吉 絹子 (90761015)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 5.  宮坂 義浩 (40507795)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  大内田 研宙 (20452708)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  INOUE Shigetaka (00529802)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  進藤 幸治 (00788432)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  甲斐 昌也 (10755242)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  藤田 逸人 (40611281)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  当間 宏樹 (80437780)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  池永 直樹 (90759755)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  水内 祐介 (20849088)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  田村 公二 (90909582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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