Nojima Iyori 野島伊世里

Researcher Number	10827398
Other IDs
Affiliation (Current)	2026: 札幌医科大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help	2019 – 2025: 札幌医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 53050:Dermatology-related Except Principal Investigator Basic Section 47040:Pharmacology-related
Keywords	Principal Investigator SIRT1 / エクソソーム / 皮膚老化 / 老化 / Prl2c3 / 皮膚 / ERK / MEF / IGFBP5 / 細胞老化 … More Except Principal Investigator … More SIRT1 / オートファジー / サルコペニア / アセチル化修飾 / ミトコンドリア / SIRT3 / MLKL / RIPK3 / ネクロプトーシス / 糖尿病 / 急性腎障害 / 骨格筋 / 老化 / マイトファジー / 心不全 Less

サルコペニアにおけるミトコンドリア蛋白アセチル化修飾の役割解明
- Principal Investigator
  
  細田隆介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Sapporo Medical University
皮膚老化における細胞老化・エクソソームの役割解明Principal Investigator
- Principal Investigator
  
  野島伊世里
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Sapporo Medical University
Roles of interplay between autophagy and necroptosis in aggravation of acute kidney injury by diabetes
- Principal Investigator
  
  久野篤史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Sapporo Medical University
Elucidating the Pathogenesis of Sarcopenia and Developing Therapies by Targeting Protein Acetylation
- Principal Investigator
  
  Hosoda Ryusuke
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Sapporo Medical University
Mechanisms of dysregulation of autophagy in heart failure
- Principal Investigator
  
  Kuno Atsushi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Sapporo Medical University
Identification and functional analysis of skin aging hormonesPrincipal Investigator
- Principal Investigator
  
  Nojima Iyori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Sapporo Medical University

All 2025 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Resveratrol, a SIRT1 activator, attenuates aging-associated alterations in skeletal muscle and heart in mice.2023
- Author(s)
  Hosoda Ryusuke, Nakashima Ryuta, Yano Masaki, Iwahara Naotoshi, Asakura Seidai, Nojima Iyori, Saga Yukika, Kunimoto Risa, Horio Yoshiyuki, Kuno Atsushi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 152 Issue: 2 Pages: 112-122
- DOI
  10.1016/j.jphs.2023.04.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06632, KAKENHI-PROJECT-20K07068
[Journal Article] Downregulation of IGFBP5 contributes to replicative senescence via ERK2 activation in mouse embryonic fibroblasts2022
- Author(s)
  Iyori Nojima, Ryusuke Hosoda, Yuki Toda, Yoshiki Saito, Naohiro Ueda, Kouhei Horimoto, Naotoshi Iwahara, Yoshiyuki Horio, Atsushi Kuno
- Journal Title
  
  Aging
  
  Volume: 14 Issue: 7 Pages: 2966-2988
- DOI
  10.18632/aging.203999
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17806, KAKENHI-PROJECT-20K07068
[Journal Article] Activation of SIRT1 promotes membrane resealing via cortactin2022
- Author(s)
  Iwahara Naotoshi、Azekami Kuya、Hosoda Ryusuke、Nojima Iyori、Hisahara Shin、Kuno Atsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 15328-15328
- DOI
  10.1038/s41598-022-19136-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07541, KAKENHI-PROJECT-20K07068, KAKENHI-PROJECT-21K15629
[Presentation] Aging and SIRT1 deficiency increase lysine acetylation of mitochondrial proteins and in the skeletal muscles: Implication in the pathogenesis in sarcopenia2025
- Author(s)
  Ryusuke Hosoda, Ryuta Nakashima, Naotoshi Iwahara, Iyori Nojima, Tatsuya Sato, Atsushi Kuno
- Organizer
  APPW2025
- Data Source
  KAKENHI-PROJECT-22K06632
[Presentation] サルコペニアの骨格筋において亢進するアセチル化蛋白の同定とそれらの機能的意義2024
- Author(s)
  細田隆介、中島龍汰、岩原直敏、野島伊世里、久野篤史
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06632
[Presentation] 加齢による皮膚菲薄化に対するSIRT1活性化薬レスベラトロールの効果2024
- Author(s)
  田村楓佳、細田隆介、野島伊世里、久野篤史
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06632
[Presentation] レスベラトロールによるSIRT1活性化はドキソルビシンによる骨格筋萎縮を改善する2024
- Author(s)
  岩舩令佳、細田隆介、中島龍汰、岩原直敏、野島伊世里、久野篤史発表標題: レスベラトロールによるSIRT1活性化はドキソルビシンによる骨格筋萎縮を改善する
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06632
[Presentation] SIRT1の活性化薬であるレスベラトロールは加齢に伴う皮膚の菲薄化を抑制する2024
- Author(s)
  田村楓佳、細田隆介、野島伊世里、久野篤史
- Organizer
  第37回北海道薬物作用談話会
- Data Source
  KAKENHI-PROJECT-22K06632
[Presentation] レスベラトロールは加齢による筋委縮と筋機能障害を軽減する2021
- Author(s)
  細田隆介, 久野篤史, 朝倉聖大, 岩原直敏, 野島伊世里, 國本梨沙, 堀尾嘉幸
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07068

1. Kuno Atsushi (30468079)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
2. 藤谷直樹 (10374191)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. Hosoda Ryusuke (20749428)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. 矢野俊之 (40444913)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 堀尾嘉幸 (30181530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 岩原直敏 (00613085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 山田崇史 (50583176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田中希尚 (60533362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 久原真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nojima Iyori 野島 伊世里

Research Projects

Research Products

Co-Researchers

サルコペニアにおけるミトコンドリア蛋白アセチル化修飾の役割解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

皮膚老化における細胞老化・エクソソームの役割解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of interplay between autophagy and necroptosis in aggravation of acute kidney injury by diabetes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the Pathogenesis of Sarcopenia and Developing Therapies by Targeting Protein Acetylation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of dysregulation of autophagy in heart failure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and functional analysis of skin aging hormonesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Resveratrol, a SIRT1 activator, attenuates aging-associated alterations in skeletal muscle and heart in mice.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Downregulation of IGFBP5 contributes to replicative senescence via ERK2 activation in mouse embryonic fibroblasts2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of SIRT1 promotes membrane resealing via cortactin2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Aging and SIRT1 deficiency increase lysine acetylation of mitochondrial proteins and in the skeletal muscles: Implication in the pathogenesis in sarcopenia2025

Author(s)

Organizer

Data Source

[Presentation] サルコペニアの骨格筋において亢進するアセチル化蛋白の同定とそれらの機能的意義2024

Author(s)

Organizer

Data Source

[Presentation] 加齢による皮膚菲薄化に対するSIRT1活性化薬レスベラトロールの効果2024

Author(s)

Organizer

Data Source

[Presentation] レスベラトロールによるSIRT1活性化はドキソルビシンによる骨格筋萎縮を改善する2024

Author(s)

Organizer

Data Source

[Presentation] SIRT1の活性化薬であるレスベラトロールは加齢に伴う皮膚の菲薄化を抑制する2024

Author(s)

Organizer

Data Source

[Presentation] レスベラトロールは加齢による筋委縮と筋機能障害を軽減する2021

Author(s)

Organizer

Data Source

Nojima Iyori 野島伊世里