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ASANO KEIICHI  浅野 恵一

ORCIDConnect your ORCID iD *help
Researcher Number 10985641
Other IDs
Affiliation (Current) 2026: 筑波大学, 生存ダイナミクス研究センター, 助教
Affiliation (based on the past Project Information) *help 2024 – 2025: 筑波大学, 生存ダイナミクス研究センター, 助教
Review Section/Research Field
Principal Investigator
Basic Section 49010:Pathological biochemistry-related
Except Principal Investigator
Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords
Principal Investigator
空間的トランスクリプトーム解析 / シングルセル解析 / 血管平滑筋細胞 / 血管内皮細胞 / 大動脈瘤
Except Principal Investigator
血管平滑筋細胞 / ECM / 血管平滑筋 / 平滑筋細胞 / 大動脈瘤 … More / 大動脈解離 / マウスモデル / 細胞外マトリクス / ナノパーティクル / 内皮細胞 / 微小領域RNAシークエンシング / 胸部大動脈 / 細胞外マトリックス Less
  • Research Projects

    (2 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (8 People)
  •  平滑筋細胞の形質転換は大動脈瘤の新規治療標的となりうるか?Principal Investigator

    • Principal Investigator
      浅野 恵一
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      University of Tsukuba
  •  Elucidation of the mechanism of thoracic aortic disease based on extracellular matrix and development of novel therapeutic strategy

    • Principal Investigator
      柳沢 裕美
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      University of Tsukuba

All 2025 2024

All Journal Article Presentation

  • [Journal Article] Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice2025

    • Author(s)
      Hossain ASM Sakhawat、Clarin Maria Thea Rane Dela Cruz、Kimura Kenichi、Biggin George、Taga Yuki、Uto Koichiro、Yamagishi Ayana、Motoyama Eri、Narenmandula、Mizuno Kazunori、Nakamura Chikashi、Asano Keiichi、Ohtsuki Sumio、Nakamura Tomoyuki、Kanki Sachiko、Baldock Clair、Raja Erna、Yanagisawa Hiromi
    • Journal Title

      Matrix Biology

      Volume: 135 Pages: 24-38

    • DOI

      10.1016/j.matbio.2024.11.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-23H04323, KAKENHI-PLANNED-23H04937, KAKENHI-PROJECT-23H00431, KAKENHI-PROJECT-23K24098, KAKENHI-PROJECT-23K18226, KAKENHI-PROJECT-21KK0151, KAKENHI-PROJECT-23K07737
  • [Journal Article] A novel genetic mouse model of fatal aortic dissection reveals massive inflammatory cell infiltration in the thoracic aorta2024

    • Author(s)
      Kimura Kenichi、Motoyama Eri、Kanki Sachiko、Asano Keiichi、Sheikh Md Al Amin、Clarin Maria Thea Rane Dela Cruz、Raja Erna、Takeda Mariko、Ishii Ryutaro、Murata Kazuya、Deleeuw Violette、Sips Patrick、Mosquera Laura Muino、De Backer Julie、Mizuno Seiya、Sakai Lynn Y、Nakamura Tomoyuki、Yanagisawa Hiromi
    • Journal Title

      bioRvix

      Volume: -

    • DOI

      10.1101/2024.05.02.592287

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23H00431, KAKENHI-PROJECT-21KK0151, KAKENHI-PROJECT-23KJ0282
  • [Presentation] A novel genetic mouse model of fatal aortic dissection rvealed massive inflammatory cell infiltration in the thoracic aorta2024

    • Author(s)
      Kenichi Kimura,, Eri Motoyama, Sachiko Kanki, Keiichi Asano, Patrick Sips, Md Al Amin Sheikh, Maria Thea Rane Dela Cruz Clarin, Erna Raja, Mariko Takeda, Ryutaro Ishii, Kazuya Murata, Violette Deleeuw, Laura Muino Mosquera, Julie De Backer, Seiya Mizuno, Lynn Y Sakai, Tomoyuki Nakamura, and Hiromi Yanagisawa1
    • Organizer
      IRAD/GenTAC Aortic meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] Fibrillin-1 G234D mutation links mouse skin tightness to elastic fi ber defects and collagen cross-linking2024

    • Author(s)
      ASM Sakhawat Hossain, Maria Thea Rane Dela Cruz, Kenichi Kimura, Yuki Taga, Koichiro Uto, Ayana Yamagishi, Eri Motoyama, Kazunori Mizuno, Chikashi Nakamura, Keiichi Asano, Sumio Ohtsuki, Tomoyuki Nakamura, Sachiko Kanki, Erna Raja, Hiromi Yanagisawa
    • Organizer
      日本結合組織学会
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] フィブリリン1遺伝子変異による大動脈解離病態に関わる血管内皮細胞の機能解析2024

    • Author(s)
      本山絵理, 木村健一、 浅野恵一, 神吉佐智子, 中邨智之, 柳沢裕美
    • Organizer
      エラスチン研究会
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] トロンボスポンジン1はメカニカルストレス応答因子として大動脈壁恒常性の維持に関わる2024

    • Author(s)
      Zou Chenlu、浅野恵一、柳沢裕美
    • Organizer
      MatriCell フォーラム
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] Phenotypic changes of endothelial cells in the pathogenesis of aortic dissection2024

    • Author(s)
      Kenichi Kimura, Eri Motoyama, Sachiko Kanki, Md Al Amin Sheikh, Keiichi Asano Violette Deleeuw, Patrick Sips, Julie De Backer, Lynn Y Sakai, Hiromi Yanagisawa
    • Organizer
      IVBM
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] トロンボスポンジン1はメカニカルストレス応答因子として大動脈壁恒常性の維持に関わる2024

    • Author(s)
      Zou Chenlu、浅野 恵一、柳沢 裕美
    • Organizer
      第8回エラスチン・関連分子研究会学術集会
    • Data Source
      KAKENHI-PROJECT-24K18377
  • [Presentation] 新規Fibrillin-1 点変異マウスモデルを用いた大動脈解離におけるメカノセンシング機構の解明2024

    • Author(s)
      本山絵理、木村健一、Clarin MTRDC、浅野恵一、神吉佐智子、柳沢裕美
    • Organizer
      日本結合組織学会
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] Investigation of the molecular pathogenesis of aortic dissection in new Fibrillin 1 mutant mice by synchrotron imaging and transcriptomics analysis2024

    • Author(s)
      Md Al Amin Sheikh, Kenichi Kimura, Eri Motoyama, Violette Deleeuw, Sachiko Kanki, Keiichi Asano, Patrick Sips, Julie De Backer, Lynn Y Sakai, Hiromi Yanagisawa
    • Organizer
      日本結合組織学会
    • Data Source
      KAKENHI-PROJECT-23H00431
  • [Presentation] 血管平滑筋細胞のメカノセンシング異常が大動脈恒常性に及ぼす影響2024

    • Author(s)
      Zou Chenlu、浅野 恵一、柳沢 裕美
    • Organizer
      第10回MatriCellフォーラム
    • Data Source
      KAKENHI-PROJECT-24K18377
  • 1.  柳沢 裕美 (40746301)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 2.  荏原 充宏 (10452393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  尾崎 遼 (10743346)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  平松 祐司 (30302417)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  徳永 千穂 (30451701)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  臼杵 豊展 (50514535)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  木村 健一 (50633153)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 8.  中邨 智之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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